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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PTPRS-ANGPTL4 (FusionGDB2 ID:70529)

Fusion Gene Summary for PTPRS-ANGPTL4

check button Fusion gene summary
Fusion gene informationFusion gene name: PTPRS-ANGPTL4
Fusion gene ID: 70529
HgeneTgene
Gene symbol

PTPRS

ANGPTL4

Gene ID

5802

51129

Gene nameprotein tyrosine phosphatase receptor type Sangiopoietin like 4
SynonymsPTPSIGMA|R-PTP-S|R-PTP-sigmaARP4|FIAF|HARP|HFARP|NL2|PGAR|TGQTL|UNQ171|pp1158
Cytomap

19p13.3

19p13.2

Type of geneprotein-codingprotein-coding
Descriptionreceptor-type tyrosine-protein phosphatase Sprotein tyrosine phosphatase PTPsigmareceptor-type tyrosine-protein phosphatase sigmaangiopoietin-related protein 4PPARG angiopoietin related proteinfasting-induced adipose factorhepatic angiopoietin-related proteinhepatic fibrinogen/angiopoietin-related proteinperoxisome proliferator-activated receptor (PPAR) gamma induced angiopoie
Modification date2020032220200322
UniProtAcc.

Q9BY76

Ensembl transtripts involved in fusion geneENST00000262963, ENST00000348075, 
ENST00000353284, ENST00000357368, 
ENST00000372412, ENST00000587303, 
ENST00000588012, ENST00000590509, 
ENST00000592099, ENST00000588552, 
ENST00000301455, ENST00000393962, 
ENST00000541807, 
Fusion gene scores* DoF score20 X 19 X 8=30404 X 4 X 3=48
# samples 236
** MAII scorelog2(23/3040*10)=-3.72436555738657
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/48*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: PTPRS [Title/Abstract] AND ANGPTL4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPTPRS(5286061)-ANGPTL4(8429090), # samples:2
PTPRS(5286061)-ANGPTL4(8430838), # samples:2
Anticipated loss of major functional domain due to fusion event.PTPRS-ANGPTL4 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
PTPRS-ANGPTL4 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
PTPRS-ANGPTL4 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePTPRS

GO:0006470

protein dephosphorylation

8524829

HgenePTPRS

GO:0099560

synaptic membrane adhesion

23345436

TgeneANGPTL4

GO:0043066

negative regulation of apoptotic process

10698685

TgeneANGPTL4

GO:0043335

protein unfolding

29899144

TgeneANGPTL4

GO:0051005

negative regulation of lipoprotein lipase activity

19542565|29899144


check buttonFusion gene breakpoints across PTPRS (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ANGPTL4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-FX-A3NK-01APTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
ChimerDB4SARCTCGA-FX-A3NK-01APTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
ChimerDB4SARCTCGA-FX-A3NKPTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
ChimerDB4SARCTCGA-QC-AA9N-01APTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
ChimerDB4SARCTCGA-QC-AA9N-01APTPRSchr19

5286061

-ANGPTL4chr19

8430838

+


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Fusion Gene ORF analysis for PTPRS-ANGPTL4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000262963ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000262963ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000262963ENST00000393962PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000262963ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000262963ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000262963ENST00000541807PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000262963ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000348075ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000348075ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000348075ENST00000393962PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000348075ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000348075ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000348075ENST00000541807PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000348075ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000353284ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000353284ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000353284ENST00000393962PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000353284ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000353284ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000353284ENST00000541807PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000353284ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000357368ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000357368ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000357368ENST00000393962PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000357368ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000357368ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000357368ENST00000541807PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000357368ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000372412ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000372412ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000372412ENST00000393962PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000372412ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000372412ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000372412ENST00000541807PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000372412ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000587303ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000587303ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000587303ENST00000393962PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000587303ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000587303ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000587303ENST00000541807PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000587303ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000588012ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000588012ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000588012ENST00000393962PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000588012ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000588012ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000588012ENST00000541807PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000588012ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000590509ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000590509ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000590509ENST00000393962PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000590509ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000590509ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000590509ENST00000541807PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000590509ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000592099ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000592099ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000592099ENST00000393962PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000592099ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5CDS-5UTRENST00000592099ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5CDS-5UTRENST00000592099ENST00000541807PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5CDS-5UTRENST00000592099ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5UTR-3CDSENST00000588552ENST00000301455PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5UTR-3CDSENST00000588552ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5UTR-5UTRENST00000588552ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5UTR-5UTRENST00000588552ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5UTR-5UTRENST00000588552ENST00000393962PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5UTR-5UTRENST00000588552ENST00000393962PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
5UTR-5UTRENST00000588552ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8429090

+
5UTR-5UTRENST00000588552ENST00000541807PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
5UTR-5UTRENST00000588552ENST00000541807PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
Frame-shiftENST00000262963ENST00000301455PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
Frame-shiftENST00000262963ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
Frame-shiftENST00000348075ENST00000301455PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
Frame-shiftENST00000348075ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
Frame-shiftENST00000353284ENST00000301455PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
Frame-shiftENST00000353284ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
Frame-shiftENST00000357368ENST00000301455PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
Frame-shiftENST00000357368ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
Frame-shiftENST00000372412ENST00000301455PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
Frame-shiftENST00000372412ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
In-frameENST00000587303ENST00000301455PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
In-frameENST00000587303ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
In-frameENST00000588012ENST00000301455PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
In-frameENST00000588012ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
In-frameENST00000590509ENST00000301455PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
In-frameENST00000590509ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+
In-frameENST00000592099ENST00000301455PTPRSchr19

5286060

-ANGPTL4chr19

8430837

+
In-frameENST00000592099ENST00000301455PTPRSchr19

5286061

-ANGPTL4chr19

8430838

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000587303PTPRSchr195286060-ENST00000301455ANGPTL4chr198430837+15811911191093324
ENST00000588012PTPRSchr195286060-ENST00000301455ANGPTL4chr198430837+1504114421016324
ENST00000592099PTPRSchr195286060-ENST00000301455ANGPTL4chr198430837+1504114421016324
ENST00000590509PTPRSchr195286060-ENST00000301455ANGPTL4chr198430837+17293392671241324
ENST00000587303PTPRSchr195286061-ENST00000301455ANGPTL4chr198430838+15811911191093324
ENST00000588012PTPRSchr195286061-ENST00000301455ANGPTL4chr198430838+1504114421016324
ENST00000592099PTPRSchr195286061-ENST00000301455ANGPTL4chr198430838+1504114421016324
ENST00000590509PTPRSchr195286061-ENST00000301455ANGPTL4chr198430838+17293392671241324

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000587303ENST00000301455PTPRSchr195286060-ANGPTL4chr198430837+0.0379689370.96203107
ENST00000588012ENST00000301455PTPRSchr195286060-ANGPTL4chr198430837+0.0404598560.9595401
ENST00000592099ENST00000301455PTPRSchr195286060-ANGPTL4chr198430837+0.0404598560.9595401
ENST00000590509ENST00000301455PTPRSchr195286060-ANGPTL4chr198430837+0.0467168880.9532831
ENST00000587303ENST00000301455PTPRSchr195286061-ANGPTL4chr198430838+0.0379689370.96203107
ENST00000588012ENST00000301455PTPRSchr195286061-ANGPTL4chr198430838+0.0404598560.9595401
ENST00000592099ENST00000301455PTPRSchr195286061-ANGPTL4chr198430838+0.0404598560.9595401
ENST00000590509ENST00000301455PTPRSchr195286061-ANGPTL4chr198430838+0.0467168880.9532831

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Fusion Genomic Features for PTPRS-ANGPTL4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PTPRSchr195286060-ANGPTL4chr198430837+1.41E-050.99998593
PTPRSchr195286060-ANGPTL4chr198430837+1.41E-050.99998593
PTPRSchr195286060-ANGPTL4chr198430837+1.41E-050.99998593
PTPRSchr195286060-ANGPTL4chr198430837+1.41E-050.99998593
PTPRSchr195286060-ANGPTL4chr198430837+1.41E-050.99998593
PTPRSchr195286060-ANGPTL4chr198430837+1.41E-050.99998593

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PTPRS-ANGPTL4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:5286061/chr19:8429090)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ANGPTL4

Q9BY76

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism (PubMed:19270337, PubMed:21398697, PubMed:27929370, PubMed:29899144). May also play a role in regulating glucose homeostasis and insulin sensitivity (Probable). Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (PubMed:14583458, PubMed:17068295). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro) (PubMed:17068295). Depending on context, may modulate tumor-related angiogenesis (By similarity). {ECO:0000250|UniProtKB:Q9Z1P8, ECO:0000269|PubMed:14583458, ECO:0000269|PubMed:17068295, ECO:0000269|PubMed:19270337, ECO:0000269|PubMed:21398697, ECO:0000269|PubMed:27929370, ECO:0000269|PubMed:29899144, ECO:0000305|PubMed:29899519}.; FUNCTION: [ANGPTL4 N-terminal chain]: Mediates inactivation of the lipoprotein lipase LPL, and thereby plays an important role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism (PubMed:19270337, PubMed:21398697, PubMed:27929370, PubMed:29899144). Has higher activity in LPL inactivation than the uncleaved protein (PubMed:19270337, PubMed:21398697). {ECO:0000269|PubMed:19270337, ECO:0000269|PubMed:21398697, ECO:0000269|PubMed:27929370, ECO:0000269|PubMed:29899144}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneANGPTL4chr19:5286060chr19:8430837ENST0000030145507179_401106407.0DomainFibrinogen C-terminal
TgeneANGPTL4chr19:5286060chr19:8430837ENST0000039396206179_401106369.0DomainFibrinogen C-terminal
TgeneANGPTL4chr19:5286061chr19:8430838ENST0000030145507179_401106407.0DomainFibrinogen C-terminal
TgeneANGPTL4chr19:5286061chr19:8430838ENST0000039396206179_401106369.0DomainFibrinogen C-terminal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-233641_644301911.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-229641_644301502.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-238641_644301949.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-137641_644301949.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-132641_644301911.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-128641_644301502.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-233641_644301911.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-229641_644301502.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-238641_644301949.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-137641_644301949.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-132641_644301911.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-128641_644301502.0Compositional biasNote=Poly-Pro
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-2331036_1120301911.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-233135_233301911.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-2331393_1648301911.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-2331680_1939301911.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-233245_327301911.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-233334_424301911.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-23333_123301911.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-233429_523301911.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-233527_616301911.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-233621_718301911.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-233723_831301911.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-233832_930301911.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-233931_1033301911.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-2291036_1120301502.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-229135_233301502.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-2291393_1648301502.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-2291680_1939301502.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-229245_327301502.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-229334_424301502.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-22933_123301502.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-229429_523301502.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-229527_616301502.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-229621_718301502.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-229723_831301502.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-229832_930301502.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-229931_1033301502.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-2381036_1120301949.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-238135_233301949.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-2381393_1648301949.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-2381680_1939301949.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-238245_327301949.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-238334_424301949.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-23833_123301949.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-238429_523301949.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-238527_616301949.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-238621_718301949.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-238723_831301949.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-238832_930301949.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-238931_1033301949.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-1371036_1120301949.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-137135_233301949.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-1371393_1648301949.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-1371680_1939301949.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-137245_327301949.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-137334_424301949.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-13733_123301949.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-137429_523301949.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-137527_616301949.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-137621_718301949.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-137723_831301949.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-137832_930301949.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-137931_1033301949.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-1321036_1120301911.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-132135_233301911.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-1321393_1648301911.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-1321680_1939301911.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-132245_327301911.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-132334_424301911.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-13233_123301911.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-132429_523301911.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-132527_616301911.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-132621_718301911.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-132723_831301911.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-132832_930301911.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-132931_1033301911.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-1281036_1120301502.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-128135_233301502.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-1281393_1648301502.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-1281680_1939301502.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-128245_327301502.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-128334_424301502.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-12833_123301502.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-128429_523301502.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-128527_616301502.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-128621_718301502.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-128723_831301502.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-128832_930301502.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-128931_1033301502.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-2331036_1120301911.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-233135_233301911.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-2331393_1648301911.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-2331680_1939301911.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-233245_327301911.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-233334_424301911.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-23333_123301911.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-233429_523301911.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-233527_616301911.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-233621_718301911.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-233723_831301911.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-233832_930301911.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-233931_1033301911.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-2291036_1120301502.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-229135_233301502.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-2291393_1648301502.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-2291680_1939301502.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-229245_327301502.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-229334_424301502.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-22933_123301502.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-229429_523301502.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-229527_616301502.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-229621_718301502.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-229723_831301502.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-229832_930301502.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-229931_1033301502.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-2381036_1120301949.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-238135_233301949.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-2381393_1648301949.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-2381680_1939301949.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-238245_327301949.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-238334_424301949.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-23833_123301949.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-238429_523301949.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-238527_616301949.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-238621_718301949.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-238723_831301949.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-238832_930301949.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-238931_1033301949.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-1371036_1120301949.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-137135_233301949.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-1371393_1648301949.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-1371680_1939301949.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-137245_327301949.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-137334_424301949.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-13733_123301949.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-137429_523301949.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-137527_616301949.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-137621_718301949.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-137723_831301949.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-137832_930301949.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-137931_1033301949.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-1321036_1120301911.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-132135_233301911.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-1321393_1648301911.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-1321680_1939301911.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-132245_327301911.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-132334_424301911.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-13233_123301911.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-132429_523301911.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-132527_616301911.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-132621_718301911.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-132723_831301911.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-132832_930301911.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-132931_1033301911.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-1281036_1120301502.0DomainFibronectin type-III 8
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-128135_233301502.0DomainNote=Ig-like C2-type 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-1281393_1648301502.0DomainTyrosine-protein phosphatase 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-1281680_1939301502.0DomainTyrosine-protein phosphatase 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-128245_327301502.0DomainNote=Ig-like C2-type 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-128334_424301502.0DomainFibronectin type-III 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-12833_123301502.0DomainNote=Ig-like C2-type 1
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-128429_523301502.0DomainFibronectin type-III 2
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-128527_616301502.0DomainFibronectin type-III 3
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-128621_718301502.0DomainFibronectin type-III 4
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-128723_831301502.0DomainFibronectin type-III 5
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-128832_930301502.0DomainFibronectin type-III 6
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-128931_1033301502.0DomainFibronectin type-III 7
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-2331589_1595301911.0RegionSubstrate binding
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-23368_72301911.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-2291589_1595301502.0RegionSubstrate binding
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-22968_72301502.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-2381589_1595301949.0RegionSubstrate binding
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-23868_72301949.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-1371589_1595301949.0RegionSubstrate binding
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-13768_72301949.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-1321589_1595301911.0RegionSubstrate binding
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-13268_72301911.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-1281589_1595301502.0RegionSubstrate binding
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-12868_72301502.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-2331589_1595301911.0RegionSubstrate binding
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-23368_72301911.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-2291589_1595301502.0RegionSubstrate binding
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-22968_72301502.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-2381589_1595301949.0RegionSubstrate binding
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-23868_72301949.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-1371589_1595301949.0RegionSubstrate binding
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-13768_72301949.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-1321589_1595301911.0RegionSubstrate binding
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-13268_72301911.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-1281589_1595301502.0RegionSubstrate binding
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-12868_72301502.0RegionImportant for binding to glycosaminoglycan chains
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-2331304_1948301911.0Topological domainCytoplasmic
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-23330_1282301911.0Topological domainExtracellular
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-2291304_1948301502.0Topological domainCytoplasmic
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-22930_1282301502.0Topological domainExtracellular
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-2381304_1948301949.0Topological domainCytoplasmic
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-23830_1282301949.0Topological domainExtracellular
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-1371304_1948301949.0Topological domainCytoplasmic
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-13730_1282301949.0Topological domainExtracellular
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-1321304_1948301911.0Topological domainCytoplasmic
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-13230_1282301911.0Topological domainExtracellular
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-1281304_1948301502.0Topological domainCytoplasmic
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-12830_1282301502.0Topological domainExtracellular
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-2331304_1948301911.0Topological domainCytoplasmic
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-23330_1282301911.0Topological domainExtracellular
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-2291304_1948301502.0Topological domainCytoplasmic
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-22930_1282301502.0Topological domainExtracellular
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-2381304_1948301949.0Topological domainCytoplasmic
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-23830_1282301949.0Topological domainExtracellular
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-1371304_1948301949.0Topological domainCytoplasmic
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-13730_1282301949.0Topological domainExtracellular
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-1321304_1948301911.0Topological domainCytoplasmic
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-13230_1282301911.0Topological domainExtracellular
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-1281304_1948301502.0Topological domainCytoplasmic
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-12830_1282301502.0Topological domainExtracellular
HgenePTPRSchr19:5286060chr19:8430837ENST00000348075-2331283_1303301911.0TransmembraneHelical
HgenePTPRSchr19:5286060chr19:8430837ENST00000353284-2291283_1303301502.0TransmembraneHelical
HgenePTPRSchr19:5286060chr19:8430837ENST00000357368-2381283_1303301949.0TransmembraneHelical
HgenePTPRSchr19:5286060chr19:8430837ENST00000587303-1371283_1303301949.0TransmembraneHelical
HgenePTPRSchr19:5286060chr19:8430837ENST00000588012-1321283_1303301911.0TransmembraneHelical
HgenePTPRSchr19:5286060chr19:8430837ENST00000592099-1281283_1303301502.0TransmembraneHelical
HgenePTPRSchr19:5286061chr19:8430838ENST00000348075-2331283_1303301911.0TransmembraneHelical
HgenePTPRSchr19:5286061chr19:8430838ENST00000353284-2291283_1303301502.0TransmembraneHelical
HgenePTPRSchr19:5286061chr19:8430838ENST00000357368-2381283_1303301949.0TransmembraneHelical
HgenePTPRSchr19:5286061chr19:8430838ENST00000587303-1371283_1303301949.0TransmembraneHelical
HgenePTPRSchr19:5286061chr19:8430838ENST00000588012-1321283_1303301911.0TransmembraneHelical
HgenePTPRSchr19:5286061chr19:8430838ENST00000592099-1281283_1303301502.0TransmembraneHelical
TgeneANGPTL4chr19:5286060chr19:8430837ENST0000030145507100_143106407.0Coiled coilOntology_term=ECO:0000255
TgeneANGPTL4chr19:5286060chr19:8430837ENST0000039396206100_143106369.0Coiled coilOntology_term=ECO:0000255
TgeneANGPTL4chr19:5286061chr19:8430838ENST0000030145507100_143106407.0Coiled coilOntology_term=ECO:0000255
TgeneANGPTL4chr19:5286061chr19:8430838ENST0000039396206100_143106369.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for PTPRS-ANGPTL4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>70529_70529_1_PTPRS-ANGPTL4_PTPRS_chr19_5286060_ENST00000587303_ANGPTL4_chr19_8430837_ENST00000301455_length(transcript)=1581nt_BP=191nt
CTGCAGACGTTGCCCCATCTGACGCTCGGCTCGAGGCCTCTCTGTGAGGGACCGGGGGGCCATCCCCCTCCAGGGCGGAGATCGGAGGTC
GCTGCCAAGCATGGCGCCCACCTGGGGCCCTGGCATGGTGTCTGTGGTTGGTCCCATGGGCCTCCTTGTGGTCCTGCTCGTTGGAGGCTG
TGCAGCAGAAGACACAACTCAAGGCTCAGAACAGCAGGATCCAGCAACTCTTCCACAAGGTGGCCCAGCAGCAGCGGCACCTGGAGAAGC
AGCACCTGCGAATTCAGCATCTGCAAAGCCAGTTTGGCCTCCTGGACCACAAGCACCTAGACCATGAGGTGGCCAAGCCTGCCCGAAGAA
AGAGGCTGCCCGAGATGGCCCAGCCAGTTGACCCGGCTCACAATGTCAGCCGCCTGCACCGGCTGCCCAGGGATTGCCAGGAGCTGTTCC
AGGTTGGGGAGAGGCAGAGTGGACTATTTGAAATCCAGCCTCAGGGGTCTCCGCCATTTTTGGTGAACTGCAAGATGACCTCAGATGGAG
GCTGGACAGTAATTCAGAGGCGCCACGATGGCTCAGTGGACTTCAACCGGCCCTGGGAAGCCTACAAGGCGGGGTTTGGGGATCCCCACG
GCGAGTTCTGGCTGGGTCTGGAGAAGGTGCATAGCATCACGGGGGACCGCAACAGCCGCCTGGCCGTGCAGCTGCGGGACTGGGATGGCA
ACGCCGAGTTGCTGCAGTTCTCCGTGCACCTGGGTGGCGAGGACACGGCCTATAGCCTGCAGCTCACTGCACCCGTGGCCGGCCAGCTGG
GCGCCACCACCGTCCCACCCAGCGGCCTCTCCGTACCCTTCTCCACTTGGGACCAGGATCACGACCTCCGCAGGGACAAGAACTGCGCCA
AGAGCCTCTCTGGAGGCTGGTGGTTTGGCACCTGCAGCCATTCCAACCTCAACGGCCAGTACTTCCGCTCCATCCCACAGCAGCGGCAGA
AGCTTAAGAAGGGAATCTTCTGGAAGACCTGGCGGGGCCGCTACTACCCGCTGCAGGCCACCACCATGTTGATCCAGCCCATGGCAGCAG
AGGCAGCCTCCTAGCGTCCTGGCTGGGCCTGGTCCCAGGCCCACGAAAGACGGTGACTCTTGGCTCTGCCCGAGGATGTGGCCGTTCCCT
GCCTGGGCAGGGGCTCCAAGGAGGGGCCATCTGGAAACTTGTGGACAGAGAAGAAGACCACGACTGGAGAAGCCCCCTTTCTGAGTGCAG
GGGGGCTGCATGCGTTGCCTCCTGAGATCGAGGCTGCAGGATATGCTCAGACTCTAGAGGCGTGGACCAAGGGGCATGGAGCTTCACTCC
TTGCTGGCCAGGGAGTTGGGGACTCAGAGGGACCACTTGGGGCCAGCCAGACTGGCCTCAATGGCGGACTCAGTCACATTGACTGACGGG
GACCAGGGCTTGTGTGGGTCGAGAGCGCCCTCATGGTGCTGGTGCTGTTGTGTGTAGGTCCCCTGGGGACACAAGCAGGCGCCAATGGTA

>70529_70529_1_PTPRS-ANGPTL4_PTPRS_chr19_5286060_ENST00000587303_ANGPTL4_chr19_8430837_ENST00000301455_length(amino acids)=324AA_BP=24
MAWCLWLVPWASLWSCSLEAVQQKTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPV
DPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKV
HSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFG

--------------------------------------------------------------
>70529_70529_2_PTPRS-ANGPTL4_PTPRS_chr19_5286060_ENST00000588012_ANGPTL4_chr19_8430837_ENST00000301455_length(transcript)=1504nt_BP=114nt
GAGATCGGAGGTCGCTGCCAAGCATGGCGCCCACCTGGGGCCCTGGCATGGTGTCTGTGGTTGGTCCCATGGGCCTCCTTGTGGTCCTGC
TCGTTGGAGGCTGTGCAGCAGAAGACACAACTCAAGGCTCAGAACAGCAGGATCCAGCAACTCTTCCACAAGGTGGCCCAGCAGCAGCGG
CACCTGGAGAAGCAGCACCTGCGAATTCAGCATCTGCAAAGCCAGTTTGGCCTCCTGGACCACAAGCACCTAGACCATGAGGTGGCCAAG
CCTGCCCGAAGAAAGAGGCTGCCCGAGATGGCCCAGCCAGTTGACCCGGCTCACAATGTCAGCCGCCTGCACCGGCTGCCCAGGGATTGC
CAGGAGCTGTTCCAGGTTGGGGAGAGGCAGAGTGGACTATTTGAAATCCAGCCTCAGGGGTCTCCGCCATTTTTGGTGAACTGCAAGATG
ACCTCAGATGGAGGCTGGACAGTAATTCAGAGGCGCCACGATGGCTCAGTGGACTTCAACCGGCCCTGGGAAGCCTACAAGGCGGGGTTT
GGGGATCCCCACGGCGAGTTCTGGCTGGGTCTGGAGAAGGTGCATAGCATCACGGGGGACCGCAACAGCCGCCTGGCCGTGCAGCTGCGG
GACTGGGATGGCAACGCCGAGTTGCTGCAGTTCTCCGTGCACCTGGGTGGCGAGGACACGGCCTATAGCCTGCAGCTCACTGCACCCGTG
GCCGGCCAGCTGGGCGCCACCACCGTCCCACCCAGCGGCCTCTCCGTACCCTTCTCCACTTGGGACCAGGATCACGACCTCCGCAGGGAC
AAGAACTGCGCCAAGAGCCTCTCTGGAGGCTGGTGGTTTGGCACCTGCAGCCATTCCAACCTCAACGGCCAGTACTTCCGCTCCATCCCA
CAGCAGCGGCAGAAGCTTAAGAAGGGAATCTTCTGGAAGACCTGGCGGGGCCGCTACTACCCGCTGCAGGCCACCACCATGTTGATCCAG
CCCATGGCAGCAGAGGCAGCCTCCTAGCGTCCTGGCTGGGCCTGGTCCCAGGCCCACGAAAGACGGTGACTCTTGGCTCTGCCCGAGGAT
GTGGCCGTTCCCTGCCTGGGCAGGGGCTCCAAGGAGGGGCCATCTGGAAACTTGTGGACAGAGAAGAAGACCACGACTGGAGAAGCCCCC
TTTCTGAGTGCAGGGGGGCTGCATGCGTTGCCTCCTGAGATCGAGGCTGCAGGATATGCTCAGACTCTAGAGGCGTGGACCAAGGGGCAT
GGAGCTTCACTCCTTGCTGGCCAGGGAGTTGGGGACTCAGAGGGACCACTTGGGGCCAGCCAGACTGGCCTCAATGGCGGACTCAGTCAC
ATTGACTGACGGGGACCAGGGCTTGTGTGGGTCGAGAGCGCCCTCATGGTGCTGGTGCTGTTGTGTGTAGGTCCCCTGGGGACACAAGCA

>70529_70529_2_PTPRS-ANGPTL4_PTPRS_chr19_5286060_ENST00000588012_ANGPTL4_chr19_8430837_ENST00000301455_length(amino acids)=324AA_BP=24
MAWCLWLVPWASLWSCSLEAVQQKTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPV
DPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKV
HSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFG

--------------------------------------------------------------
>70529_70529_3_PTPRS-ANGPTL4_PTPRS_chr19_5286060_ENST00000590509_ANGPTL4_chr19_8430837_ENST00000301455_length(transcript)=1729nt_BP=339nt
ATTCCATCCCATCACCCCATGATCCTTCCCCATTGTCCCATGACCAGCCCCCGCAGGACCCTCCCCTGCTCCATGTGACCCTCCCTCTGC
CTCCTCCATGAAGGTCTCCTGGATTTCCCCACTCGCCTCTCACAGCCCTCCATTGTCTCTGCAGACGTTGCCCCATCTGACGCTCGGCTC
GAGGCCTCTCTGTGAGGGACCGGGGGGCCATCCCCCTCCAGGGCGGAGATCGGAGGTCGCTGCCAAGCATGGCGCCCACCTGGGGCCCTG
GCATGGTGTCTGTGGTTGGTCCCATGGGCCTCCTTGTGGTCCTGCTCGTTGGAGGCTGTGCAGCAGAAGACACAACTCAAGGCTCAGAAC
AGCAGGATCCAGCAACTCTTCCACAAGGTGGCCCAGCAGCAGCGGCACCTGGAGAAGCAGCACCTGCGAATTCAGCATCTGCAAAGCCAG
TTTGGCCTCCTGGACCACAAGCACCTAGACCATGAGGTGGCCAAGCCTGCCCGAAGAAAGAGGCTGCCCGAGATGGCCCAGCCAGTTGAC
CCGGCTCACAATGTCAGCCGCCTGCACCGGCTGCCCAGGGATTGCCAGGAGCTGTTCCAGGTTGGGGAGAGGCAGAGTGGACTATTTGAA
ATCCAGCCTCAGGGGTCTCCGCCATTTTTGGTGAACTGCAAGATGACCTCAGATGGAGGCTGGACAGTAATTCAGAGGCGCCACGATGGC
TCAGTGGACTTCAACCGGCCCTGGGAAGCCTACAAGGCGGGGTTTGGGGATCCCCACGGCGAGTTCTGGCTGGGTCTGGAGAAGGTGCAT
AGCATCACGGGGGACCGCAACAGCCGCCTGGCCGTGCAGCTGCGGGACTGGGATGGCAACGCCGAGTTGCTGCAGTTCTCCGTGCACCTG
GGTGGCGAGGACACGGCCTATAGCCTGCAGCTCACTGCACCCGTGGCCGGCCAGCTGGGCGCCACCACCGTCCCACCCAGCGGCCTCTCC
GTACCCTTCTCCACTTGGGACCAGGATCACGACCTCCGCAGGGACAAGAACTGCGCCAAGAGCCTCTCTGGAGGCTGGTGGTTTGGCACC
TGCAGCCATTCCAACCTCAACGGCCAGTACTTCCGCTCCATCCCACAGCAGCGGCAGAAGCTTAAGAAGGGAATCTTCTGGAAGACCTGG
CGGGGCCGCTACTACCCGCTGCAGGCCACCACCATGTTGATCCAGCCCATGGCAGCAGAGGCAGCCTCCTAGCGTCCTGGCTGGGCCTGG
TCCCAGGCCCACGAAAGACGGTGACTCTTGGCTCTGCCCGAGGATGTGGCCGTTCCCTGCCTGGGCAGGGGCTCCAAGGAGGGGCCATCT
GGAAACTTGTGGACAGAGAAGAAGACCACGACTGGAGAAGCCCCCTTTCTGAGTGCAGGGGGGCTGCATGCGTTGCCTCCTGAGATCGAG
GCTGCAGGATATGCTCAGACTCTAGAGGCGTGGACCAAGGGGCATGGAGCTTCACTCCTTGCTGGCCAGGGAGTTGGGGACTCAGAGGGA
CCACTTGGGGCCAGCCAGACTGGCCTCAATGGCGGACTCAGTCACATTGACTGACGGGGACCAGGGCTTGTGTGGGTCGAGAGCGCCCTC
ATGGTGCTGGTGCTGTTGTGTGTAGGTCCCCTGGGGACACAAGCAGGCGCCAATGGTATCTGGGCGGAGCTCACAGAGTTCTTGGAATAA

>70529_70529_3_PTPRS-ANGPTL4_PTPRS_chr19_5286060_ENST00000590509_ANGPTL4_chr19_8430837_ENST00000301455_length(amino acids)=324AA_BP=24
MAWCLWLVPWASLWSCSLEAVQQKTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPV
DPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKV
HSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFG

--------------------------------------------------------------
>70529_70529_4_PTPRS-ANGPTL4_PTPRS_chr19_5286060_ENST00000592099_ANGPTL4_chr19_8430837_ENST00000301455_length(transcript)=1504nt_BP=114nt
GAGATCGGAGGTCGCTGCCAAGCATGGCGCCCACCTGGGGCCCTGGCATGGTGTCTGTGGTTGGTCCCATGGGCCTCCTTGTGGTCCTGC
TCGTTGGAGGCTGTGCAGCAGAAGACACAACTCAAGGCTCAGAACAGCAGGATCCAGCAACTCTTCCACAAGGTGGCCCAGCAGCAGCGG
CACCTGGAGAAGCAGCACCTGCGAATTCAGCATCTGCAAAGCCAGTTTGGCCTCCTGGACCACAAGCACCTAGACCATGAGGTGGCCAAG
CCTGCCCGAAGAAAGAGGCTGCCCGAGATGGCCCAGCCAGTTGACCCGGCTCACAATGTCAGCCGCCTGCACCGGCTGCCCAGGGATTGC
CAGGAGCTGTTCCAGGTTGGGGAGAGGCAGAGTGGACTATTTGAAATCCAGCCTCAGGGGTCTCCGCCATTTTTGGTGAACTGCAAGATG
ACCTCAGATGGAGGCTGGACAGTAATTCAGAGGCGCCACGATGGCTCAGTGGACTTCAACCGGCCCTGGGAAGCCTACAAGGCGGGGTTT
GGGGATCCCCACGGCGAGTTCTGGCTGGGTCTGGAGAAGGTGCATAGCATCACGGGGGACCGCAACAGCCGCCTGGCCGTGCAGCTGCGG
GACTGGGATGGCAACGCCGAGTTGCTGCAGTTCTCCGTGCACCTGGGTGGCGAGGACACGGCCTATAGCCTGCAGCTCACTGCACCCGTG
GCCGGCCAGCTGGGCGCCACCACCGTCCCACCCAGCGGCCTCTCCGTACCCTTCTCCACTTGGGACCAGGATCACGACCTCCGCAGGGAC
AAGAACTGCGCCAAGAGCCTCTCTGGAGGCTGGTGGTTTGGCACCTGCAGCCATTCCAACCTCAACGGCCAGTACTTCCGCTCCATCCCA
CAGCAGCGGCAGAAGCTTAAGAAGGGAATCTTCTGGAAGACCTGGCGGGGCCGCTACTACCCGCTGCAGGCCACCACCATGTTGATCCAG
CCCATGGCAGCAGAGGCAGCCTCCTAGCGTCCTGGCTGGGCCTGGTCCCAGGCCCACGAAAGACGGTGACTCTTGGCTCTGCCCGAGGAT
GTGGCCGTTCCCTGCCTGGGCAGGGGCTCCAAGGAGGGGCCATCTGGAAACTTGTGGACAGAGAAGAAGACCACGACTGGAGAAGCCCCC
TTTCTGAGTGCAGGGGGGCTGCATGCGTTGCCTCCTGAGATCGAGGCTGCAGGATATGCTCAGACTCTAGAGGCGTGGACCAAGGGGCAT
GGAGCTTCACTCCTTGCTGGCCAGGGAGTTGGGGACTCAGAGGGACCACTTGGGGCCAGCCAGACTGGCCTCAATGGCGGACTCAGTCAC
ATTGACTGACGGGGACCAGGGCTTGTGTGGGTCGAGAGCGCCCTCATGGTGCTGGTGCTGTTGTGTGTAGGTCCCCTGGGGACACAAGCA

>70529_70529_4_PTPRS-ANGPTL4_PTPRS_chr19_5286060_ENST00000592099_ANGPTL4_chr19_8430837_ENST00000301455_length(amino acids)=324AA_BP=24
MAWCLWLVPWASLWSCSLEAVQQKTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPV
DPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKV
HSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFG

--------------------------------------------------------------
>70529_70529_5_PTPRS-ANGPTL4_PTPRS_chr19_5286061_ENST00000587303_ANGPTL4_chr19_8430838_ENST00000301455_length(transcript)=1581nt_BP=191nt
CTGCAGACGTTGCCCCATCTGACGCTCGGCTCGAGGCCTCTCTGTGAGGGACCGGGGGGCCATCCCCCTCCAGGGCGGAGATCGGAGGTC
GCTGCCAAGCATGGCGCCCACCTGGGGCCCTGGCATGGTGTCTGTGGTTGGTCCCATGGGCCTCCTTGTGGTCCTGCTCGTTGGAGGCTG
TGCAGCAGAAGACACAACTCAAGGCTCAGAACAGCAGGATCCAGCAACTCTTCCACAAGGTGGCCCAGCAGCAGCGGCACCTGGAGAAGC
AGCACCTGCGAATTCAGCATCTGCAAAGCCAGTTTGGCCTCCTGGACCACAAGCACCTAGACCATGAGGTGGCCAAGCCTGCCCGAAGAA
AGAGGCTGCCCGAGATGGCCCAGCCAGTTGACCCGGCTCACAATGTCAGCCGCCTGCACCGGCTGCCCAGGGATTGCCAGGAGCTGTTCC
AGGTTGGGGAGAGGCAGAGTGGACTATTTGAAATCCAGCCTCAGGGGTCTCCGCCATTTTTGGTGAACTGCAAGATGACCTCAGATGGAG
GCTGGACAGTAATTCAGAGGCGCCACGATGGCTCAGTGGACTTCAACCGGCCCTGGGAAGCCTACAAGGCGGGGTTTGGGGATCCCCACG
GCGAGTTCTGGCTGGGTCTGGAGAAGGTGCATAGCATCACGGGGGACCGCAACAGCCGCCTGGCCGTGCAGCTGCGGGACTGGGATGGCA
ACGCCGAGTTGCTGCAGTTCTCCGTGCACCTGGGTGGCGAGGACACGGCCTATAGCCTGCAGCTCACTGCACCCGTGGCCGGCCAGCTGG
GCGCCACCACCGTCCCACCCAGCGGCCTCTCCGTACCCTTCTCCACTTGGGACCAGGATCACGACCTCCGCAGGGACAAGAACTGCGCCA
AGAGCCTCTCTGGAGGCTGGTGGTTTGGCACCTGCAGCCATTCCAACCTCAACGGCCAGTACTTCCGCTCCATCCCACAGCAGCGGCAGA
AGCTTAAGAAGGGAATCTTCTGGAAGACCTGGCGGGGCCGCTACTACCCGCTGCAGGCCACCACCATGTTGATCCAGCCCATGGCAGCAG
AGGCAGCCTCCTAGCGTCCTGGCTGGGCCTGGTCCCAGGCCCACGAAAGACGGTGACTCTTGGCTCTGCCCGAGGATGTGGCCGTTCCCT
GCCTGGGCAGGGGCTCCAAGGAGGGGCCATCTGGAAACTTGTGGACAGAGAAGAAGACCACGACTGGAGAAGCCCCCTTTCTGAGTGCAG
GGGGGCTGCATGCGTTGCCTCCTGAGATCGAGGCTGCAGGATATGCTCAGACTCTAGAGGCGTGGACCAAGGGGCATGGAGCTTCACTCC
TTGCTGGCCAGGGAGTTGGGGACTCAGAGGGACCACTTGGGGCCAGCCAGACTGGCCTCAATGGCGGACTCAGTCACATTGACTGACGGG
GACCAGGGCTTGTGTGGGTCGAGAGCGCCCTCATGGTGCTGGTGCTGTTGTGTGTAGGTCCCCTGGGGACACAAGCAGGCGCCAATGGTA

>70529_70529_5_PTPRS-ANGPTL4_PTPRS_chr19_5286061_ENST00000587303_ANGPTL4_chr19_8430838_ENST00000301455_length(amino acids)=324AA_BP=24
MAWCLWLVPWASLWSCSLEAVQQKTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPV
DPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKV
HSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFG

--------------------------------------------------------------
>70529_70529_6_PTPRS-ANGPTL4_PTPRS_chr19_5286061_ENST00000588012_ANGPTL4_chr19_8430838_ENST00000301455_length(transcript)=1504nt_BP=114nt
GAGATCGGAGGTCGCTGCCAAGCATGGCGCCCACCTGGGGCCCTGGCATGGTGTCTGTGGTTGGTCCCATGGGCCTCCTTGTGGTCCTGC
TCGTTGGAGGCTGTGCAGCAGAAGACACAACTCAAGGCTCAGAACAGCAGGATCCAGCAACTCTTCCACAAGGTGGCCCAGCAGCAGCGG
CACCTGGAGAAGCAGCACCTGCGAATTCAGCATCTGCAAAGCCAGTTTGGCCTCCTGGACCACAAGCACCTAGACCATGAGGTGGCCAAG
CCTGCCCGAAGAAAGAGGCTGCCCGAGATGGCCCAGCCAGTTGACCCGGCTCACAATGTCAGCCGCCTGCACCGGCTGCCCAGGGATTGC
CAGGAGCTGTTCCAGGTTGGGGAGAGGCAGAGTGGACTATTTGAAATCCAGCCTCAGGGGTCTCCGCCATTTTTGGTGAACTGCAAGATG
ACCTCAGATGGAGGCTGGACAGTAATTCAGAGGCGCCACGATGGCTCAGTGGACTTCAACCGGCCCTGGGAAGCCTACAAGGCGGGGTTT
GGGGATCCCCACGGCGAGTTCTGGCTGGGTCTGGAGAAGGTGCATAGCATCACGGGGGACCGCAACAGCCGCCTGGCCGTGCAGCTGCGG
GACTGGGATGGCAACGCCGAGTTGCTGCAGTTCTCCGTGCACCTGGGTGGCGAGGACACGGCCTATAGCCTGCAGCTCACTGCACCCGTG
GCCGGCCAGCTGGGCGCCACCACCGTCCCACCCAGCGGCCTCTCCGTACCCTTCTCCACTTGGGACCAGGATCACGACCTCCGCAGGGAC
AAGAACTGCGCCAAGAGCCTCTCTGGAGGCTGGTGGTTTGGCACCTGCAGCCATTCCAACCTCAACGGCCAGTACTTCCGCTCCATCCCA
CAGCAGCGGCAGAAGCTTAAGAAGGGAATCTTCTGGAAGACCTGGCGGGGCCGCTACTACCCGCTGCAGGCCACCACCATGTTGATCCAG
CCCATGGCAGCAGAGGCAGCCTCCTAGCGTCCTGGCTGGGCCTGGTCCCAGGCCCACGAAAGACGGTGACTCTTGGCTCTGCCCGAGGAT
GTGGCCGTTCCCTGCCTGGGCAGGGGCTCCAAGGAGGGGCCATCTGGAAACTTGTGGACAGAGAAGAAGACCACGACTGGAGAAGCCCCC
TTTCTGAGTGCAGGGGGGCTGCATGCGTTGCCTCCTGAGATCGAGGCTGCAGGATATGCTCAGACTCTAGAGGCGTGGACCAAGGGGCAT
GGAGCTTCACTCCTTGCTGGCCAGGGAGTTGGGGACTCAGAGGGACCACTTGGGGCCAGCCAGACTGGCCTCAATGGCGGACTCAGTCAC
ATTGACTGACGGGGACCAGGGCTTGTGTGGGTCGAGAGCGCCCTCATGGTGCTGGTGCTGTTGTGTGTAGGTCCCCTGGGGACACAAGCA

>70529_70529_6_PTPRS-ANGPTL4_PTPRS_chr19_5286061_ENST00000588012_ANGPTL4_chr19_8430838_ENST00000301455_length(amino acids)=324AA_BP=24
MAWCLWLVPWASLWSCSLEAVQQKTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPV
DPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKV
HSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFG

--------------------------------------------------------------
>70529_70529_7_PTPRS-ANGPTL4_PTPRS_chr19_5286061_ENST00000590509_ANGPTL4_chr19_8430838_ENST00000301455_length(transcript)=1729nt_BP=339nt
ATTCCATCCCATCACCCCATGATCCTTCCCCATTGTCCCATGACCAGCCCCCGCAGGACCCTCCCCTGCTCCATGTGACCCTCCCTCTGC
CTCCTCCATGAAGGTCTCCTGGATTTCCCCACTCGCCTCTCACAGCCCTCCATTGTCTCTGCAGACGTTGCCCCATCTGACGCTCGGCTC
GAGGCCTCTCTGTGAGGGACCGGGGGGCCATCCCCCTCCAGGGCGGAGATCGGAGGTCGCTGCCAAGCATGGCGCCCACCTGGGGCCCTG
GCATGGTGTCTGTGGTTGGTCCCATGGGCCTCCTTGTGGTCCTGCTCGTTGGAGGCTGTGCAGCAGAAGACACAACTCAAGGCTCAGAAC
AGCAGGATCCAGCAACTCTTCCACAAGGTGGCCCAGCAGCAGCGGCACCTGGAGAAGCAGCACCTGCGAATTCAGCATCTGCAAAGCCAG
TTTGGCCTCCTGGACCACAAGCACCTAGACCATGAGGTGGCCAAGCCTGCCCGAAGAAAGAGGCTGCCCGAGATGGCCCAGCCAGTTGAC
CCGGCTCACAATGTCAGCCGCCTGCACCGGCTGCCCAGGGATTGCCAGGAGCTGTTCCAGGTTGGGGAGAGGCAGAGTGGACTATTTGAA
ATCCAGCCTCAGGGGTCTCCGCCATTTTTGGTGAACTGCAAGATGACCTCAGATGGAGGCTGGACAGTAATTCAGAGGCGCCACGATGGC
TCAGTGGACTTCAACCGGCCCTGGGAAGCCTACAAGGCGGGGTTTGGGGATCCCCACGGCGAGTTCTGGCTGGGTCTGGAGAAGGTGCAT
AGCATCACGGGGGACCGCAACAGCCGCCTGGCCGTGCAGCTGCGGGACTGGGATGGCAACGCCGAGTTGCTGCAGTTCTCCGTGCACCTG
GGTGGCGAGGACACGGCCTATAGCCTGCAGCTCACTGCACCCGTGGCCGGCCAGCTGGGCGCCACCACCGTCCCACCCAGCGGCCTCTCC
GTACCCTTCTCCACTTGGGACCAGGATCACGACCTCCGCAGGGACAAGAACTGCGCCAAGAGCCTCTCTGGAGGCTGGTGGTTTGGCACC
TGCAGCCATTCCAACCTCAACGGCCAGTACTTCCGCTCCATCCCACAGCAGCGGCAGAAGCTTAAGAAGGGAATCTTCTGGAAGACCTGG
CGGGGCCGCTACTACCCGCTGCAGGCCACCACCATGTTGATCCAGCCCATGGCAGCAGAGGCAGCCTCCTAGCGTCCTGGCTGGGCCTGG
TCCCAGGCCCACGAAAGACGGTGACTCTTGGCTCTGCCCGAGGATGTGGCCGTTCCCTGCCTGGGCAGGGGCTCCAAGGAGGGGCCATCT
GGAAACTTGTGGACAGAGAAGAAGACCACGACTGGAGAAGCCCCCTTTCTGAGTGCAGGGGGGCTGCATGCGTTGCCTCCTGAGATCGAG
GCTGCAGGATATGCTCAGACTCTAGAGGCGTGGACCAAGGGGCATGGAGCTTCACTCCTTGCTGGCCAGGGAGTTGGGGACTCAGAGGGA
CCACTTGGGGCCAGCCAGACTGGCCTCAATGGCGGACTCAGTCACATTGACTGACGGGGACCAGGGCTTGTGTGGGTCGAGAGCGCCCTC
ATGGTGCTGGTGCTGTTGTGTGTAGGTCCCCTGGGGACACAAGCAGGCGCCAATGGTATCTGGGCGGAGCTCACAGAGTTCTTGGAATAA

>70529_70529_7_PTPRS-ANGPTL4_PTPRS_chr19_5286061_ENST00000590509_ANGPTL4_chr19_8430838_ENST00000301455_length(amino acids)=324AA_BP=24
MAWCLWLVPWASLWSCSLEAVQQKTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPV
DPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKV
HSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFG

--------------------------------------------------------------
>70529_70529_8_PTPRS-ANGPTL4_PTPRS_chr19_5286061_ENST00000592099_ANGPTL4_chr19_8430838_ENST00000301455_length(transcript)=1504nt_BP=114nt
GAGATCGGAGGTCGCTGCCAAGCATGGCGCCCACCTGGGGCCCTGGCATGGTGTCTGTGGTTGGTCCCATGGGCCTCCTTGTGGTCCTGC
TCGTTGGAGGCTGTGCAGCAGAAGACACAACTCAAGGCTCAGAACAGCAGGATCCAGCAACTCTTCCACAAGGTGGCCCAGCAGCAGCGG
CACCTGGAGAAGCAGCACCTGCGAATTCAGCATCTGCAAAGCCAGTTTGGCCTCCTGGACCACAAGCACCTAGACCATGAGGTGGCCAAG
CCTGCCCGAAGAAAGAGGCTGCCCGAGATGGCCCAGCCAGTTGACCCGGCTCACAATGTCAGCCGCCTGCACCGGCTGCCCAGGGATTGC
CAGGAGCTGTTCCAGGTTGGGGAGAGGCAGAGTGGACTATTTGAAATCCAGCCTCAGGGGTCTCCGCCATTTTTGGTGAACTGCAAGATG
ACCTCAGATGGAGGCTGGACAGTAATTCAGAGGCGCCACGATGGCTCAGTGGACTTCAACCGGCCCTGGGAAGCCTACAAGGCGGGGTTT
GGGGATCCCCACGGCGAGTTCTGGCTGGGTCTGGAGAAGGTGCATAGCATCACGGGGGACCGCAACAGCCGCCTGGCCGTGCAGCTGCGG
GACTGGGATGGCAACGCCGAGTTGCTGCAGTTCTCCGTGCACCTGGGTGGCGAGGACACGGCCTATAGCCTGCAGCTCACTGCACCCGTG
GCCGGCCAGCTGGGCGCCACCACCGTCCCACCCAGCGGCCTCTCCGTACCCTTCTCCACTTGGGACCAGGATCACGACCTCCGCAGGGAC
AAGAACTGCGCCAAGAGCCTCTCTGGAGGCTGGTGGTTTGGCACCTGCAGCCATTCCAACCTCAACGGCCAGTACTTCCGCTCCATCCCA
CAGCAGCGGCAGAAGCTTAAGAAGGGAATCTTCTGGAAGACCTGGCGGGGCCGCTACTACCCGCTGCAGGCCACCACCATGTTGATCCAG
CCCATGGCAGCAGAGGCAGCCTCCTAGCGTCCTGGCTGGGCCTGGTCCCAGGCCCACGAAAGACGGTGACTCTTGGCTCTGCCCGAGGAT
GTGGCCGTTCCCTGCCTGGGCAGGGGCTCCAAGGAGGGGCCATCTGGAAACTTGTGGACAGAGAAGAAGACCACGACTGGAGAAGCCCCC
TTTCTGAGTGCAGGGGGGCTGCATGCGTTGCCTCCTGAGATCGAGGCTGCAGGATATGCTCAGACTCTAGAGGCGTGGACCAAGGGGCAT
GGAGCTTCACTCCTTGCTGGCCAGGGAGTTGGGGACTCAGAGGGACCACTTGGGGCCAGCCAGACTGGCCTCAATGGCGGACTCAGTCAC
ATTGACTGACGGGGACCAGGGCTTGTGTGGGTCGAGAGCGCCCTCATGGTGCTGGTGCTGTTGTGTGTAGGTCCCCTGGGGACACAAGCA

>70529_70529_8_PTPRS-ANGPTL4_PTPRS_chr19_5286061_ENST00000592099_ANGPTL4_chr19_8430838_ENST00000301455_length(amino acids)=324AA_BP=24
MAWCLWLVPWASLWSCSLEAVQQKTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPV
DPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKV
HSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PTPRS-ANGPTL4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PTPRS-ANGPTL4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PTPRS-ANGPTL4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource