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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PTPRU-C10orf76 (FusionGDB2 ID:70568)

Fusion Gene Summary for PTPRU-C10orf76

check button Fusion gene summary
Fusion gene informationFusion gene name: PTPRU-C10orf76
Fusion gene ID: 70568
HgeneTgene
Gene symbol

PTPRU

C10orf76

Gene ID

10076

79591

Gene nameprotein tyrosine phosphatase receptor type Uarmadillo like helical domain containing 3
SynonymsFMI|PCP-2|PTP|PTP-J|PTP-PI|PTP-RO|PTPPSI|PTPRO|PTPU2|R-PTP-PSI|R-PTP-U|hPTP-JC10orf76
Cytomap

1p35.3

10q24.32

Type of geneprotein-codingprotein-coding
Descriptionreceptor-type tyrosine-protein phosphatase UPTP piReceptor protein tyrosine phosphatase hPTP-Jpancreatic carcinoma phosphatase 2pi R-PTP-Psiprotein-tyrosine phosphatase Jprotein-tyrosine phosphatase piprotein-tyrosine phosphatase receptor omicronrarmadillo-like helical domain-containing protein 3UPF0668 protein C10orf76
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000323874, ENST00000345512, 
ENST00000356870, ENST00000373779, 
ENST00000428026, ENST00000460170, 
ENST00000415600, 		ENST00000311122, 
ENST00000495001, ENST00000370033, 
Fusion gene scores* DoF score8 X 6 X 7=3368 X 6 X 5=240
# samples 109
** MAII scorelog2(10/336*10)=-1.74846123300404
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/240*10)=-1.41503749927884
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PTPRU [Title/Abstract] AND C10orf76 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPTPRU(29587415)-C10orf76(103699695), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePTPRU

GO:0006470

protein dephosphorylation

12501215

HgenePTPRU

GO:0008285

negative regulation of cell proliferation

16574648

HgenePTPRU

GO:0030336

negative regulation of cell migration

12501215|16574648

HgenePTPRU

GO:0034394

protein localization to cell surface

16574648

HgenePTPRU

GO:0090090

negative regulation of canonical Wnt signaling pathway

16574648

HgenePTPRU

GO:2000049

positive regulation of cell-cell adhesion mediated by cadherin

16574648


check buttonFusion gene breakpoints across PTPRU (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across C10orf76 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-A4GN-01APTPRUchr1

29587415

+C10orf76chr10

103699695

-


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Fusion Gene ORF analysis for PTPRU-C10orf76

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000323874ENST00000311122PTPRUchr1

29587415

+C10orf76chr10

103699695

-
5CDS-intronENST00000323874ENST00000495001PTPRUchr1

29587415

+C10orf76chr10

103699695

-
5CDS-intronENST00000345512ENST00000311122PTPRUchr1

29587415

+C10orf76chr10

103699695

-
5CDS-intronENST00000345512ENST00000495001PTPRUchr1

29587415

+C10orf76chr10

103699695

-
5CDS-intronENST00000356870ENST00000311122PTPRUchr1

29587415

+C10orf76chr10

103699695

-
5CDS-intronENST00000356870ENST00000495001PTPRUchr1

29587415

+C10orf76chr10

103699695

-
5CDS-intronENST00000373779ENST00000311122PTPRUchr1

29587415

+C10orf76chr10

103699695

-
5CDS-intronENST00000373779ENST00000495001PTPRUchr1

29587415

+C10orf76chr10

103699695

-
5CDS-intronENST00000428026ENST00000311122PTPRUchr1

29587415

+C10orf76chr10

103699695

-
5CDS-intronENST00000428026ENST00000495001PTPRUchr1

29587415

+C10orf76chr10

103699695

-
5CDS-intronENST00000460170ENST00000311122PTPRUchr1

29587415

+C10orf76chr10

103699695

-
5CDS-intronENST00000460170ENST00000495001PTPRUchr1

29587415

+C10orf76chr10

103699695

-
In-frameENST00000323874ENST00000370033PTPRUchr1

29587415

+C10orf76chr10

103699695

-
In-frameENST00000345512ENST00000370033PTPRUchr1

29587415

+C10orf76chr10

103699695

-
In-frameENST00000356870ENST00000370033PTPRUchr1

29587415

+C10orf76chr10

103699695

-
In-frameENST00000373779ENST00000370033PTPRUchr1

29587415

+C10orf76chr10

103699695

-
In-frameENST00000428026ENST00000370033PTPRUchr1

29587415

+C10orf76chr10

103699695

-
In-frameENST00000460170ENST00000370033PTPRUchr1

29587415

+C10orf76chr10

103699695

-
intron-3CDSENST00000415600ENST00000370033PTPRUchr1

29587415

+C10orf76chr10

103699695

-
intron-intronENST00000415600ENST00000311122PTPRUchr1

29587415

+C10orf76chr10

103699695

-
intron-intronENST00000415600ENST00000495001PTPRUchr1

29587415

+C10orf76chr10

103699695

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000345512PTPRUchr129587415+ENST00000370033C10orf76chr10103699695-356712731291637502
ENST00000373779PTPRUchr129587415+ENST00000370033C10orf76chr10103699695-356712731291637502
ENST00000356870PTPRUchr129587415+ENST00000370033C10orf76chr10103699695-354812541101618502
ENST00000323874PTPRUchr129587415+ENST00000370033C10orf76chr10103699695-354812541101618502
ENST00000428026PTPRUchr129587415+ENST00000370033C10orf76chr10103699695-35341240961604502
ENST00000460170PTPRUchr129587415+ENST00000370033C10orf76chr10103699695-3444115061514502

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000345512ENST00000370033PTPRUchr129587415+C10orf76chr10103699695-0.0062523830.9937476
ENST00000373779ENST00000370033PTPRUchr129587415+C10orf76chr10103699695-0.0062523830.9937476
ENST00000356870ENST00000370033PTPRUchr129587415+C10orf76chr10103699695-0.0063830350.99361694
ENST00000323874ENST00000370033PTPRUchr129587415+C10orf76chr10103699695-0.0063830350.99361694
ENST00000428026ENST00000370033PTPRUchr129587415+C10orf76chr10103699695-0.0062327920.99376726
ENST00000460170ENST00000370033PTPRUchr129587415+C10orf76chr10103699695-0.0053138920.9946861

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Fusion Genomic Features for PTPRU-C10orf76


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PTPRU-C10orf76


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:29587415/chr10:103699695)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+731190_2753811447.0DomainNote=Ig-like C2-type
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+73125_1883811447.0DomainMAM
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+731288_3833811447.0DomainFibronectin type-III 1
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+730190_2753811437.0DomainNote=Ig-like C2-type
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+73025_1883811437.0DomainMAM
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+730288_3833811437.0DomainFibronectin type-III 1
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+730190_2753811434.0DomainNote=Ig-like C2-type
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+73025_1883811434.0DomainMAM
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+730288_3833811434.0DomainFibronectin type-III 1
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+731190_2753811441.0DomainNote=Ig-like C2-type
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+73125_1883811441.0DomainMAM
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+731288_3833811441.0DomainFibronectin type-III 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+7311176_14393811447.0DomainTyrosine-protein phosphatase 2
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+731386_4843811447.0DomainFibronectin type-III 2
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+731485_5913811447.0DomainFibronectin type-III 3
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+731592_6743811447.0DomainFibronectin type-III 4
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+731888_11443811447.0DomainTyrosine-protein phosphatase 1
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+7301176_14393811437.0DomainTyrosine-protein phosphatase 2
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+730386_4843811437.0DomainFibronectin type-III 2
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+730485_5913811437.0DomainFibronectin type-III 3
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+730592_6743811437.0DomainFibronectin type-III 4
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+730888_11443811437.0DomainTyrosine-protein phosphatase 1
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+7301176_14393811434.0DomainTyrosine-protein phosphatase 2
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+730386_4843811434.0DomainFibronectin type-III 2
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+730485_5913811434.0DomainFibronectin type-III 3
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+730592_6743811434.0DomainFibronectin type-III 4
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+730888_11443811434.0DomainTyrosine-protein phosphatase 1
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+7311176_14393811441.0DomainTyrosine-protein phosphatase 2
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+731386_4843811441.0DomainFibronectin type-III 2
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+731485_5913811441.0DomainFibronectin type-III 3
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+731592_6743811441.0DomainFibronectin type-III 4
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+731888_11443811441.0DomainTyrosine-protein phosphatase 1
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+7311085_10913811447.0RegionSubstrate binding
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+7301085_10913811437.0RegionSubstrate binding
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+7301085_10913811434.0RegionSubstrate binding
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+7311085_10913811441.0RegionSubstrate binding
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+73119_7493811447.0Topological domainExtracellular
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+731771_14463811447.0Topological domainCytoplasmic
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+73019_7493811437.0Topological domainExtracellular
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+730771_14463811437.0Topological domainCytoplasmic
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+73019_7493811434.0Topological domainExtracellular
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+730771_14463811434.0Topological domainCytoplasmic
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+73119_7493811441.0Topological domainExtracellular
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+731771_14463811441.0Topological domainCytoplasmic
HgenePTPRUchr1:29587415chr10:103699695ENST00000345512+731750_7703811447.0TransmembraneHelical
HgenePTPRUchr1:29587415chr10:103699695ENST00000373779+730750_7703811437.0TransmembraneHelical
HgenePTPRUchr1:29587415chr10:103699695ENST00000428026+730750_7703811434.0TransmembraneHelical
HgenePTPRUchr1:29587415chr10:103699695ENST00000460170+731750_7703811441.0TransmembraneHelical
TgeneC10orf76chr1:29587415chr10:103699695ENST000003700332126520_538568690.0TransmembraneHelical


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Fusion Gene Sequence for PTPRU-C10orf76


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>70568_70568_1_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000323874_C10orf76_chr10_103699695_ENST00000370033_length(transcript)=3548nt_BP=1254nt
GCCGCGCCGCTCCGCTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCCCCCGCGCCGGGCCCCGGGA
CGGGCGGCGACGCTCCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGG
CAGCTGGCTGCACCTTCGAGGAGGCAAGTGACCCAGCAGTGCCCTGCGAGTACAGCCAGGCCCAGTACGATGACTTCCAGTGGGAGCAAG
TGCGAATCCACCCTGGCACCCGGGCACCTGCGGACCTGCCCCACGGCTCCTACTTGATGGTCAACACTTCCCAGCATGCCCCAGGCCAGC
GAGCCCATGTCATCTTCCAGAGCCTGAGCGAGAATGATACCCACTGTGTGCAGTTCAGCTACTTCCTGTACAGCCGGGACGGGCACAGCC
CGGGCACCCTGGGCGTCTACGTGCGCGTTAATGGGGGCCCCCTGGGCAGTGCTGTGTGGAATATGACTGGATCCCACGGCCGTCAGTGGC
ACCAGGCTGAGCTGGCTGTCAGCACTTTCTGGCCCAATGAATATCAGGTGCTGTTTGAGGCCCTCATCTCCCCAGACCGCAGGGGCTACA
TGGGCCTAGATGACATCCTGCTTCTCAGCTACCCCTGCGCAAAGGCCCCACACTTCTCCCGCCTGGGCGACGTGGAGGTCAACGCGGGCC
AGAACGCGTCGTTCCAGTGCATGGCCGCGGGCAGAGCGGCCGAGGCCGAACGCTTCCTCTTGCAACGGCAGAGCGGGGCGCTGGTGCCGG
CGGCGGGCGTGCGGCACATCAGCCACCGGCGCTTCCTGGCCACTTTCCCGCTGGCTGCCGTGAGCCGCGCCGAGCAGGACCTGTACCGCT
GTGTGTCCCAGGCCCCGCGCGGCGCGGGCGTCTCTAACTTCGCGGAGCTCATCGTCAAGGAGCCCCCAACTCCCATCGCGCCCCCACAGC
TGCTGCGTGCTGGCCCCACCTACCTCATCATCCAGCTCAACACCAACTCCATCATTGGCGACGGGCCGATCGTGCGCAAGGAGATTGAGT
ACCGCATGGCGCGCGGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAGACCTACAAGCTGTGGCACCTCGACCCCGACACAGAGTATG
AGATCAGCGTGCTGCTCACGCGTCCCGGAGACGGCGGCACTGGCCGCCCTGGGCCACCCCTCATCAGCCGCACCAAATGCGCAGTCCTGA
GGCTTTCTACCAATGCAGGCCAGTGGAAGGAAGCAGCTAGCAAGGTGACCCATGCATTGGTTAATATCAGAGCCATCATCAACCACTTTA
ACCCCAAAATTGAGTCCTACGCTGCTGTGAATCACATATCCCAACTGTCAGAGGAGCAGGTGCTGGAGGTGGTGAGAGCCAACTATGACA
CGCTCACGCTGAAGCTGCAGGATGGCCTGGACCAGTATGAGCGCTACTCAGAGCAGCACAAGGAAGCTGCCTTCTTCAAAGAGCTGGTTC
GATCCATTAGCACCAACGTCCGGAGAAACCTGGCCTTCCACACACTCAGCCAAGAAGTCCTGCTCAAGGAGTTCTCCACTATCTCCTGAG
GCCACGCCTACCTGAGCAGCCTCTGACTGCCCTTACCCATGAGGATCATGGGCTGGAGGGGGAGCGAGGGGAGAGGGGGCTGCCCCCGAG
GTTGGAGAGAAACACAGATACCAAGTTCTCTTGGTGAAGACCGCACTTCAATGGAGCTTGGGCAGCAGGGGCAGGAGGGTCAAGCCAGGG
ATAATCTTATTTGGGGAGGAATGGGTGGGCACAGTGGGGAGAGGCCTCCAGGAATGTGGGGACTTCCAGAGTGGGCTCCCTAAACAGCCC
CTCACATTTCCAATCTTGAGGTTACAAGCTGTAGCTACTGACTAATTTTCGGGAGCTGGTGAGGCAAGCCTCAGGGTAATGCCAGCACCC
TGAAAGTCAGTGGCTCTGCTCGGCTTCTGAAAACAGATCAACTCTCAGATATAGCTGGAGCTACATCCTGCTTCCTTTGGGCCTGGGGCT
GTGCTTGGCTTGAAATCTGTGTCCCCTGCCTGCACTGGCACTTTGTCCAGTCATCGGGACCTTTGGCTCAGATTTAGGGTAAGATAGGAA
TAGGGTACCTTTTTCCTTTTTTTTCTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAATGCAGTGGCGTGATCTCGGCTTTACTGCAG
CCTCCGCTTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGAGCGTGTGCCACGCCCGGCTAATTTTT
TGTATTTTTAGTAGAGATGGGGTTTCACCATGTTACCCAGGATGGTCTCAATATCCTGAGTTCATGATCCACCCACCTTGGCCTCCCAAA
GTGCTGGGATTACAGGCGTGAGCCACCACACCCAGCCAGTTTTCCTATTTTCTGAATTCAGAATTGACTTCTCTGGGAAAACTGGAGATG
AGAATCTGCCCAGTGCTCTGCTGTCCAGTCACCGCCTTTTGAATTTTAGTTTTGGCACCAGGAGTACCGTTAGCTTTCCCCTTCTTCTGG
CCCATTTGACTCATCAGCACAATAGGGTCACCACCTTAACTTTTAATTTCTAATCTGCTTTACTGTCTTTAGGGTGTGTATGAAATAAAC
ATTGACAGGCTTTCTGGAGCCCTCAAGGTGCCTACTTTGCTGGTTCCCTTTCCAGCAGCTCCCCCACCTCCCTTAGCCCCCCCTCCTCTG
GCAGCCTCTCCTGCCTCTGCTGAGCTCCCCTCCACGTGTTCCACCCCCTTACCCTGCTGTTGTTTACATCCAACCTGCCTGAGAATTTCC
TCTGGGGAGGAATCTATTCCTGTCATGGTCTAGTGCCTGGGAGGGAGAGAACTTTCTGGGGGTAGGGTGCCCTCCATCTGAAACAGGCCA
GGTGAGCATCATGCATAAGGCCTCCATTCTGTCCGCTCAGATTCTGGGTGGGGCCACAGGCAAATCTCCTGACTTATGGGGAGTTGGCTT
GTGGTTCCTCCCTTGGATAGCCTCCATGGAACCACTATAGGCTTTCCCAACAGCTGCCTCTGAAATAGCTGCTGCTTCGAGATCCTCCCT
TTTTAAAGCACTTTCTAAAGCCCTCAGGATGGCGGGAGCAAACAGCACTGGTATATTCTAGGAGTAAGTGCAGGAATTCAGCAGTGAGAG
CATGTCTGGGACCACCTGGACTGCCATCCATTTAACCTCAAATCTCTTTGGGATACTCGCCCTCCCTGGGAACCAGAGTTCTGGCTCTAA
CATTGAGCAGCTATGCACTAGTTCCAGAGAAGCCACTAACAGGCTGCCATGTGTAGATGTAGGTTCTTAAGAGATCACAGGCTGGGTCAT
CTGATCACTGGATGGATAGCTCAGCCTGGGGCATTTAGTGTTTTCCCTGGTGATAAATCCCCAAGGCAGCTGGATTTGGAGCTGGTGGCA

>70568_70568_1_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000323874_C10orf76_chr10_103699695_ENST00000370033_length(amino acids)=502AA_BP=380
MARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQ
SLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLDDIL
LLSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFLLQRQSGALVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPR
GAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEISVLLT
RPGDGGTGRPGPPLISRTKCAVLRLSTNAGQWKEAASKVTHALVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQ

--------------------------------------------------------------
>70568_70568_2_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000345512_C10orf76_chr10_103699695_ENST00000370033_length(transcript)=3567nt_BP=1273nt
GGCGCCAGTCCCGCTCCGCGCCGCGCCGCTCCGCTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCC
CCCGCGCCGGGCCCCGGGACGGGCGGCGACGCTCCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCG
CCGGAGACCGAGACTCCGGCAGCTGGCTGCACCTTCGAGGAGGCAAGTGACCCAGCAGTGCCCTGCGAGTACAGCCAGGCCCAGTACGAT
GACTTCCAGTGGGAGCAAGTGCGAATCCACCCTGGCACCCGGGCACCTGCGGACCTGCCCCACGGCTCCTACTTGATGGTCAACACTTCC
CAGCATGCCCCAGGCCAGCGAGCCCATGTCATCTTCCAGAGCCTGAGCGAGAATGATACCCACTGTGTGCAGTTCAGCTACTTCCTGTAC
AGCCGGGACGGGCACAGCCCGGGCACCCTGGGCGTCTACGTGCGCGTTAATGGGGGCCCCCTGGGCAGTGCTGTGTGGAATATGACTGGA
TCCCACGGCCGTCAGTGGCACCAGGCTGAGCTGGCTGTCAGCACTTTCTGGCCCAATGAATATCAGGTGCTGTTTGAGGCCCTCATCTCC
CCAGACCGCAGGGGCTACATGGGCCTAGATGACATCCTGCTTCTCAGCTACCCCTGCGCAAAGGCCCCACACTTCTCCCGCCTGGGCGAC
GTGGAGGTCAACGCGGGCCAGAACGCGTCGTTCCAGTGCATGGCCGCGGGCAGAGCGGCCGAGGCCGAACGCTTCCTCTTGCAACGGCAG
AGCGGGGCGCTGGTGCCGGCGGCGGGCGTGCGGCACATCAGCCACCGGCGCTTCCTGGCCACTTTCCCGCTGGCTGCCGTGAGCCGCGCC
GAGCAGGACCTGTACCGCTGTGTGTCCCAGGCCCCGCGCGGCGCGGGCGTCTCTAACTTCGCGGAGCTCATCGTCAAGGAGCCCCCAACT
CCCATCGCGCCCCCACAGCTGCTGCGTGCTGGCCCCACCTACCTCATCATCCAGCTCAACACCAACTCCATCATTGGCGACGGGCCGATC
GTGCGCAAGGAGATTGAGTACCGCATGGCGCGCGGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAGACCTACAAGCTGTGGCACCTC
GACCCCGACACAGAGTATGAGATCAGCGTGCTGCTCACGCGTCCCGGAGACGGCGGCACTGGCCGCCCTGGGCCACCCCTCATCAGCCGC
ACCAAATGCGCAGTCCTGAGGCTTTCTACCAATGCAGGCCAGTGGAAGGAAGCAGCTAGCAAGGTGACCCATGCATTGGTTAATATCAGA
GCCATCATCAACCACTTTAACCCCAAAATTGAGTCCTACGCTGCTGTGAATCACATATCCCAACTGTCAGAGGAGCAGGTGCTGGAGGTG
GTGAGAGCCAACTATGACACGCTCACGCTGAAGCTGCAGGATGGCCTGGACCAGTATGAGCGCTACTCAGAGCAGCACAAGGAAGCTGCC
TTCTTCAAAGAGCTGGTTCGATCCATTAGCACCAACGTCCGGAGAAACCTGGCCTTCCACACACTCAGCCAAGAAGTCCTGCTCAAGGAG
TTCTCCACTATCTCCTGAGGCCACGCCTACCTGAGCAGCCTCTGACTGCCCTTACCCATGAGGATCATGGGCTGGAGGGGGAGCGAGGGG
AGAGGGGGCTGCCCCCGAGGTTGGAGAGAAACACAGATACCAAGTTCTCTTGGTGAAGACCGCACTTCAATGGAGCTTGGGCAGCAGGGG
CAGGAGGGTCAAGCCAGGGATAATCTTATTTGGGGAGGAATGGGTGGGCACAGTGGGGAGAGGCCTCCAGGAATGTGGGGACTTCCAGAG
TGGGCTCCCTAAACAGCCCCTCACATTTCCAATCTTGAGGTTACAAGCTGTAGCTACTGACTAATTTTCGGGAGCTGGTGAGGCAAGCCT
CAGGGTAATGCCAGCACCCTGAAAGTCAGTGGCTCTGCTCGGCTTCTGAAAACAGATCAACTCTCAGATATAGCTGGAGCTACATCCTGC
TTCCTTTGGGCCTGGGGCTGTGCTTGGCTTGAAATCTGTGTCCCCTGCCTGCACTGGCACTTTGTCCAGTCATCGGGACCTTTGGCTCAG
ATTTAGGGTAAGATAGGAATAGGGTACCTTTTTCCTTTTTTTTCTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAATGCAGTGGCGT
GATCTCGGCTTTACTGCAGCCTCCGCTTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGAGCGTGTG
CCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTACCCAGGATGGTCTCAATATCCTGAGTTCATGATCCA
CCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCCAGCCAGTTTTCCTATTTTCTGAATTCAGAATTGACTTC
TCTGGGAAAACTGGAGATGAGAATCTGCCCAGTGCTCTGCTGTCCAGTCACCGCCTTTTGAATTTTAGTTTTGGCACCAGGAGTACCGTT
AGCTTTCCCCTTCTTCTGGCCCATTTGACTCATCAGCACAATAGGGTCACCACCTTAACTTTTAATTTCTAATCTGCTTTACTGTCTTTA
GGGTGTGTATGAAATAAACATTGACAGGCTTTCTGGAGCCCTCAAGGTGCCTACTTTGCTGGTTCCCTTTCCAGCAGCTCCCCCACCTCC
CTTAGCCCCCCCTCCTCTGGCAGCCTCTCCTGCCTCTGCTGAGCTCCCCTCCACGTGTTCCACCCCCTTACCCTGCTGTTGTTTACATCC
AACCTGCCTGAGAATTTCCTCTGGGGAGGAATCTATTCCTGTCATGGTCTAGTGCCTGGGAGGGAGAGAACTTTCTGGGGGTAGGGTGCC
CTCCATCTGAAACAGGCCAGGTGAGCATCATGCATAAGGCCTCCATTCTGTCCGCTCAGATTCTGGGTGGGGCCACAGGCAAATCTCCTG
ACTTATGGGGAGTTGGCTTGTGGTTCCTCCCTTGGATAGCCTCCATGGAACCACTATAGGCTTTCCCAACAGCTGCCTCTGAAATAGCTG
CTGCTTCGAGATCCTCCCTTTTTAAAGCACTTTCTAAAGCCCTCAGGATGGCGGGAGCAAACAGCACTGGTATATTCTAGGAGTAAGTGC
AGGAATTCAGCAGTGAGAGCATGTCTGGGACCACCTGGACTGCCATCCATTTAACCTCAAATCTCTTTGGGATACTCGCCCTCCCTGGGA
ACCAGAGTTCTGGCTCTAACATTGAGCAGCTATGCACTAGTTCCAGAGAAGCCACTAACAGGCTGCCATGTGTAGATGTAGGTTCTTAAG
AGATCACAGGCTGGGTCATCTGATCACTGGATGGATAGCTCAGCCTGGGGCATTTAGTGTTTTCCCTGGTGATAAATCCCCAAGGCAGCT

>70568_70568_2_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000345512_C10orf76_chr10_103699695_ENST00000370033_length(amino acids)=502AA_BP=380
MARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQ
SLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLDDIL
LLSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFLLQRQSGALVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPR
GAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEISVLLT
RPGDGGTGRPGPPLISRTKCAVLRLSTNAGQWKEAASKVTHALVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQ

--------------------------------------------------------------
>70568_70568_3_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000356870_C10orf76_chr10_103699695_ENST00000370033_length(transcript)=3548nt_BP=1254nt
GCCGCGCCGCTCCGCTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCCCCCGCGCCGGGCCCCGGGA
CGGGCGGCGACGCTCCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGG
CAGCTGGCTGCACCTTCGAGGAGGCAAGTGACCCAGCAGTGCCCTGCGAGTACAGCCAGGCCCAGTACGATGACTTCCAGTGGGAGCAAG
TGCGAATCCACCCTGGCACCCGGGCACCTGCGGACCTGCCCCACGGCTCCTACTTGATGGTCAACACTTCCCAGCATGCCCCAGGCCAGC
GAGCCCATGTCATCTTCCAGAGCCTGAGCGAGAATGATACCCACTGTGTGCAGTTCAGCTACTTCCTGTACAGCCGGGACGGGCACAGCC
CGGGCACCCTGGGCGTCTACGTGCGCGTTAATGGGGGCCCCCTGGGCAGTGCTGTGTGGAATATGACTGGATCCCACGGCCGTCAGTGGC
ACCAGGCTGAGCTGGCTGTCAGCACTTTCTGGCCCAATGAATATCAGGTGCTGTTTGAGGCCCTCATCTCCCCAGACCGCAGGGGCTACA
TGGGCCTAGATGACATCCTGCTTCTCAGCTACCCCTGCGCAAAGGCCCCACACTTCTCCCGCCTGGGCGACGTGGAGGTCAACGCGGGCC
AGAACGCGTCGTTCCAGTGCATGGCCGCGGGCAGAGCGGCCGAGGCCGAACGCTTCCTCTTGCAACGGCAGAGCGGGGCGCTGGTGCCGG
CGGCGGGCGTGCGGCACATCAGCCACCGGCGCTTCCTGGCCACTTTCCCGCTGGCTGCCGTGAGCCGCGCCGAGCAGGACCTGTACCGCT
GTGTGTCCCAGGCCCCGCGCGGCGCGGGCGTCTCTAACTTCGCGGAGCTCATCGTCAAGGAGCCCCCAACTCCCATCGCGCCCCCACAGC
TGCTGCGTGCTGGCCCCACCTACCTCATCATCCAGCTCAACACCAACTCCATCATTGGCGACGGGCCGATCGTGCGCAAGGAGATTGAGT
ACCGCATGGCGCGCGGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAGACCTACAAGCTGTGGCACCTCGACCCCGACACAGAGTATG
AGATCAGCGTGCTGCTCACGCGTCCCGGAGACGGCGGCACTGGCCGCCCTGGGCCACCCCTCATCAGCCGCACCAAATGCGCAGTCCTGA
GGCTTTCTACCAATGCAGGCCAGTGGAAGGAAGCAGCTAGCAAGGTGACCCATGCATTGGTTAATATCAGAGCCATCATCAACCACTTTA
ACCCCAAAATTGAGTCCTACGCTGCTGTGAATCACATATCCCAACTGTCAGAGGAGCAGGTGCTGGAGGTGGTGAGAGCCAACTATGACA
CGCTCACGCTGAAGCTGCAGGATGGCCTGGACCAGTATGAGCGCTACTCAGAGCAGCACAAGGAAGCTGCCTTCTTCAAAGAGCTGGTTC
GATCCATTAGCACCAACGTCCGGAGAAACCTGGCCTTCCACACACTCAGCCAAGAAGTCCTGCTCAAGGAGTTCTCCACTATCTCCTGAG
GCCACGCCTACCTGAGCAGCCTCTGACTGCCCTTACCCATGAGGATCATGGGCTGGAGGGGGAGCGAGGGGAGAGGGGGCTGCCCCCGAG
GTTGGAGAGAAACACAGATACCAAGTTCTCTTGGTGAAGACCGCACTTCAATGGAGCTTGGGCAGCAGGGGCAGGAGGGTCAAGCCAGGG
ATAATCTTATTTGGGGAGGAATGGGTGGGCACAGTGGGGAGAGGCCTCCAGGAATGTGGGGACTTCCAGAGTGGGCTCCCTAAACAGCCC
CTCACATTTCCAATCTTGAGGTTACAAGCTGTAGCTACTGACTAATTTTCGGGAGCTGGTGAGGCAAGCCTCAGGGTAATGCCAGCACCC
TGAAAGTCAGTGGCTCTGCTCGGCTTCTGAAAACAGATCAACTCTCAGATATAGCTGGAGCTACATCCTGCTTCCTTTGGGCCTGGGGCT
GTGCTTGGCTTGAAATCTGTGTCCCCTGCCTGCACTGGCACTTTGTCCAGTCATCGGGACCTTTGGCTCAGATTTAGGGTAAGATAGGAA
TAGGGTACCTTTTTCCTTTTTTTTCTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAATGCAGTGGCGTGATCTCGGCTTTACTGCAG
CCTCCGCTTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGAGCGTGTGCCACGCCCGGCTAATTTTT
TGTATTTTTAGTAGAGATGGGGTTTCACCATGTTACCCAGGATGGTCTCAATATCCTGAGTTCATGATCCACCCACCTTGGCCTCCCAAA
GTGCTGGGATTACAGGCGTGAGCCACCACACCCAGCCAGTTTTCCTATTTTCTGAATTCAGAATTGACTTCTCTGGGAAAACTGGAGATG
AGAATCTGCCCAGTGCTCTGCTGTCCAGTCACCGCCTTTTGAATTTTAGTTTTGGCACCAGGAGTACCGTTAGCTTTCCCCTTCTTCTGG
CCCATTTGACTCATCAGCACAATAGGGTCACCACCTTAACTTTTAATTTCTAATCTGCTTTACTGTCTTTAGGGTGTGTATGAAATAAAC
ATTGACAGGCTTTCTGGAGCCCTCAAGGTGCCTACTTTGCTGGTTCCCTTTCCAGCAGCTCCCCCACCTCCCTTAGCCCCCCCTCCTCTG
GCAGCCTCTCCTGCCTCTGCTGAGCTCCCCTCCACGTGTTCCACCCCCTTACCCTGCTGTTGTTTACATCCAACCTGCCTGAGAATTTCC
TCTGGGGAGGAATCTATTCCTGTCATGGTCTAGTGCCTGGGAGGGAGAGAACTTTCTGGGGGTAGGGTGCCCTCCATCTGAAACAGGCCA
GGTGAGCATCATGCATAAGGCCTCCATTCTGTCCGCTCAGATTCTGGGTGGGGCCACAGGCAAATCTCCTGACTTATGGGGAGTTGGCTT
GTGGTTCCTCCCTTGGATAGCCTCCATGGAACCACTATAGGCTTTCCCAACAGCTGCCTCTGAAATAGCTGCTGCTTCGAGATCCTCCCT
TTTTAAAGCACTTTCTAAAGCCCTCAGGATGGCGGGAGCAAACAGCACTGGTATATTCTAGGAGTAAGTGCAGGAATTCAGCAGTGAGAG
CATGTCTGGGACCACCTGGACTGCCATCCATTTAACCTCAAATCTCTTTGGGATACTCGCCCTCCCTGGGAACCAGAGTTCTGGCTCTAA
CATTGAGCAGCTATGCACTAGTTCCAGAGAAGCCACTAACAGGCTGCCATGTGTAGATGTAGGTTCTTAAGAGATCACAGGCTGGGTCAT
CTGATCACTGGATGGATAGCTCAGCCTGGGGCATTTAGTGTTTTCCCTGGTGATAAATCCCCAAGGCAGCTGGATTTGGAGCTGGTGGCA

>70568_70568_3_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000356870_C10orf76_chr10_103699695_ENST00000370033_length(amino acids)=502AA_BP=380
MARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQ
SLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLDDIL
LLSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFLLQRQSGALVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPR
GAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEISVLLT
RPGDGGTGRPGPPLISRTKCAVLRLSTNAGQWKEAASKVTHALVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQ

--------------------------------------------------------------
>70568_70568_4_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000373779_C10orf76_chr10_103699695_ENST00000370033_length(transcript)=3567nt_BP=1273nt
GGCGCCAGTCCCGCTCCGCGCCGCGCCGCTCCGCTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCC
CCCGCGCCGGGCCCCGGGACGGGCGGCGACGCTCCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCG
CCGGAGACCGAGACTCCGGCAGCTGGCTGCACCTTCGAGGAGGCAAGTGACCCAGCAGTGCCCTGCGAGTACAGCCAGGCCCAGTACGAT
GACTTCCAGTGGGAGCAAGTGCGAATCCACCCTGGCACCCGGGCACCTGCGGACCTGCCCCACGGCTCCTACTTGATGGTCAACACTTCC
CAGCATGCCCCAGGCCAGCGAGCCCATGTCATCTTCCAGAGCCTGAGCGAGAATGATACCCACTGTGTGCAGTTCAGCTACTTCCTGTAC
AGCCGGGACGGGCACAGCCCGGGCACCCTGGGCGTCTACGTGCGCGTTAATGGGGGCCCCCTGGGCAGTGCTGTGTGGAATATGACTGGA
TCCCACGGCCGTCAGTGGCACCAGGCTGAGCTGGCTGTCAGCACTTTCTGGCCCAATGAATATCAGGTGCTGTTTGAGGCCCTCATCTCC
CCAGACCGCAGGGGCTACATGGGCCTAGATGACATCCTGCTTCTCAGCTACCCCTGCGCAAAGGCCCCACACTTCTCCCGCCTGGGCGAC
GTGGAGGTCAACGCGGGCCAGAACGCGTCGTTCCAGTGCATGGCCGCGGGCAGAGCGGCCGAGGCCGAACGCTTCCTCTTGCAACGGCAG
AGCGGGGCGCTGGTGCCGGCGGCGGGCGTGCGGCACATCAGCCACCGGCGCTTCCTGGCCACTTTCCCGCTGGCTGCCGTGAGCCGCGCC
GAGCAGGACCTGTACCGCTGTGTGTCCCAGGCCCCGCGCGGCGCGGGCGTCTCTAACTTCGCGGAGCTCATCGTCAAGGAGCCCCCAACT
CCCATCGCGCCCCCACAGCTGCTGCGTGCTGGCCCCACCTACCTCATCATCCAGCTCAACACCAACTCCATCATTGGCGACGGGCCGATC
GTGCGCAAGGAGATTGAGTACCGCATGGCGCGCGGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAGACCTACAAGCTGTGGCACCTC
GACCCCGACACAGAGTATGAGATCAGCGTGCTGCTCACGCGTCCCGGAGACGGCGGCACTGGCCGCCCTGGGCCACCCCTCATCAGCCGC
ACCAAATGCGCAGTCCTGAGGCTTTCTACCAATGCAGGCCAGTGGAAGGAAGCAGCTAGCAAGGTGACCCATGCATTGGTTAATATCAGA
GCCATCATCAACCACTTTAACCCCAAAATTGAGTCCTACGCTGCTGTGAATCACATATCCCAACTGTCAGAGGAGCAGGTGCTGGAGGTG
GTGAGAGCCAACTATGACACGCTCACGCTGAAGCTGCAGGATGGCCTGGACCAGTATGAGCGCTACTCAGAGCAGCACAAGGAAGCTGCC
TTCTTCAAAGAGCTGGTTCGATCCATTAGCACCAACGTCCGGAGAAACCTGGCCTTCCACACACTCAGCCAAGAAGTCCTGCTCAAGGAG
TTCTCCACTATCTCCTGAGGCCACGCCTACCTGAGCAGCCTCTGACTGCCCTTACCCATGAGGATCATGGGCTGGAGGGGGAGCGAGGGG
AGAGGGGGCTGCCCCCGAGGTTGGAGAGAAACACAGATACCAAGTTCTCTTGGTGAAGACCGCACTTCAATGGAGCTTGGGCAGCAGGGG
CAGGAGGGTCAAGCCAGGGATAATCTTATTTGGGGAGGAATGGGTGGGCACAGTGGGGAGAGGCCTCCAGGAATGTGGGGACTTCCAGAG
TGGGCTCCCTAAACAGCCCCTCACATTTCCAATCTTGAGGTTACAAGCTGTAGCTACTGACTAATTTTCGGGAGCTGGTGAGGCAAGCCT
CAGGGTAATGCCAGCACCCTGAAAGTCAGTGGCTCTGCTCGGCTTCTGAAAACAGATCAACTCTCAGATATAGCTGGAGCTACATCCTGC
TTCCTTTGGGCCTGGGGCTGTGCTTGGCTTGAAATCTGTGTCCCCTGCCTGCACTGGCACTTTGTCCAGTCATCGGGACCTTTGGCTCAG
ATTTAGGGTAAGATAGGAATAGGGTACCTTTTTCCTTTTTTTTCTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAATGCAGTGGCGT
GATCTCGGCTTTACTGCAGCCTCCGCTTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGAGCGTGTG
CCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTACCCAGGATGGTCTCAATATCCTGAGTTCATGATCCA
CCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCCAGCCAGTTTTCCTATTTTCTGAATTCAGAATTGACTTC
TCTGGGAAAACTGGAGATGAGAATCTGCCCAGTGCTCTGCTGTCCAGTCACCGCCTTTTGAATTTTAGTTTTGGCACCAGGAGTACCGTT
AGCTTTCCCCTTCTTCTGGCCCATTTGACTCATCAGCACAATAGGGTCACCACCTTAACTTTTAATTTCTAATCTGCTTTACTGTCTTTA
GGGTGTGTATGAAATAAACATTGACAGGCTTTCTGGAGCCCTCAAGGTGCCTACTTTGCTGGTTCCCTTTCCAGCAGCTCCCCCACCTCC
CTTAGCCCCCCCTCCTCTGGCAGCCTCTCCTGCCTCTGCTGAGCTCCCCTCCACGTGTTCCACCCCCTTACCCTGCTGTTGTTTACATCC
AACCTGCCTGAGAATTTCCTCTGGGGAGGAATCTATTCCTGTCATGGTCTAGTGCCTGGGAGGGAGAGAACTTTCTGGGGGTAGGGTGCC
CTCCATCTGAAACAGGCCAGGTGAGCATCATGCATAAGGCCTCCATTCTGTCCGCTCAGATTCTGGGTGGGGCCACAGGCAAATCTCCTG
ACTTATGGGGAGTTGGCTTGTGGTTCCTCCCTTGGATAGCCTCCATGGAACCACTATAGGCTTTCCCAACAGCTGCCTCTGAAATAGCTG
CTGCTTCGAGATCCTCCCTTTTTAAAGCACTTTCTAAAGCCCTCAGGATGGCGGGAGCAAACAGCACTGGTATATTCTAGGAGTAAGTGC
AGGAATTCAGCAGTGAGAGCATGTCTGGGACCACCTGGACTGCCATCCATTTAACCTCAAATCTCTTTGGGATACTCGCCCTCCCTGGGA
ACCAGAGTTCTGGCTCTAACATTGAGCAGCTATGCACTAGTTCCAGAGAAGCCACTAACAGGCTGCCATGTGTAGATGTAGGTTCTTAAG
AGATCACAGGCTGGGTCATCTGATCACTGGATGGATAGCTCAGCCTGGGGCATTTAGTGTTTTCCCTGGTGATAAATCCCCAAGGCAGCT

>70568_70568_4_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000373779_C10orf76_chr10_103699695_ENST00000370033_length(amino acids)=502AA_BP=380
MARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQ
SLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLDDIL
LLSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFLLQRQSGALVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPR
GAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEISVLLT
RPGDGGTGRPGPPLISRTKCAVLRLSTNAGQWKEAASKVTHALVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQ

--------------------------------------------------------------
>70568_70568_5_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000428026_C10orf76_chr10_103699695_ENST00000370033_length(transcript)=3534nt_BP=1240nt
CTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCCCCCGCGCCGGGCCCCGGGACGGGCGGCGACGCT
CCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGGCAGCTGGCTGCACC
TTCGAGGAGGCAAGTGACCCAGCAGTGCCCTGCGAGTACAGCCAGGCCCAGTACGATGACTTCCAGTGGGAGCAAGTGCGAATCCACCCT
GGCACCCGGGCACCTGCGGACCTGCCCCACGGCTCCTACTTGATGGTCAACACTTCCCAGCATGCCCCAGGCCAGCGAGCCCATGTCATC
TTCCAGAGCCTGAGCGAGAATGATACCCACTGTGTGCAGTTCAGCTACTTCCTGTACAGCCGGGACGGGCACAGCCCGGGCACCCTGGGC
GTCTACGTGCGCGTTAATGGGGGCCCCCTGGGCAGTGCTGTGTGGAATATGACTGGATCCCACGGCCGTCAGTGGCACCAGGCTGAGCTG
GCTGTCAGCACTTTCTGGCCCAATGAATATCAGGTGCTGTTTGAGGCCCTCATCTCCCCAGACCGCAGGGGCTACATGGGCCTAGATGAC
ATCCTGCTTCTCAGCTACCCCTGCGCAAAGGCCCCACACTTCTCCCGCCTGGGCGACGTGGAGGTCAACGCGGGCCAGAACGCGTCGTTC
CAGTGCATGGCCGCGGGCAGAGCGGCCGAGGCCGAACGCTTCCTCTTGCAACGGCAGAGCGGGGCGCTGGTGCCGGCGGCGGGCGTGCGG
CACATCAGCCACCGGCGCTTCCTGGCCACTTTCCCGCTGGCTGCCGTGAGCCGCGCCGAGCAGGACCTGTACCGCTGTGTGTCCCAGGCC
CCGCGCGGCGCGGGCGTCTCTAACTTCGCGGAGCTCATCGTCAAGGAGCCCCCAACTCCCATCGCGCCCCCACAGCTGCTGCGTGCTGGC
CCCACCTACCTCATCATCCAGCTCAACACCAACTCCATCATTGGCGACGGGCCGATCGTGCGCAAGGAGATTGAGTACCGCATGGCGCGC
GGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAGACCTACAAGCTGTGGCACCTCGACCCCGACACAGAGTATGAGATCAGCGTGCTG
CTCACGCGTCCCGGAGACGGCGGCACTGGCCGCCCTGGGCCACCCCTCATCAGCCGCACCAAATGCGCAGTCCTGAGGCTTTCTACCAAT
GCAGGCCAGTGGAAGGAAGCAGCTAGCAAGGTGACCCATGCATTGGTTAATATCAGAGCCATCATCAACCACTTTAACCCCAAAATTGAG
TCCTACGCTGCTGTGAATCACATATCCCAACTGTCAGAGGAGCAGGTGCTGGAGGTGGTGAGAGCCAACTATGACACGCTCACGCTGAAG
CTGCAGGATGGCCTGGACCAGTATGAGCGCTACTCAGAGCAGCACAAGGAAGCTGCCTTCTTCAAAGAGCTGGTTCGATCCATTAGCACC
AACGTCCGGAGAAACCTGGCCTTCCACACACTCAGCCAAGAAGTCCTGCTCAAGGAGTTCTCCACTATCTCCTGAGGCCACGCCTACCTG
AGCAGCCTCTGACTGCCCTTACCCATGAGGATCATGGGCTGGAGGGGGAGCGAGGGGAGAGGGGGCTGCCCCCGAGGTTGGAGAGAAACA
CAGATACCAAGTTCTCTTGGTGAAGACCGCACTTCAATGGAGCTTGGGCAGCAGGGGCAGGAGGGTCAAGCCAGGGATAATCTTATTTGG
GGAGGAATGGGTGGGCACAGTGGGGAGAGGCCTCCAGGAATGTGGGGACTTCCAGAGTGGGCTCCCTAAACAGCCCCTCACATTTCCAAT
CTTGAGGTTACAAGCTGTAGCTACTGACTAATTTTCGGGAGCTGGTGAGGCAAGCCTCAGGGTAATGCCAGCACCCTGAAAGTCAGTGGC
TCTGCTCGGCTTCTGAAAACAGATCAACTCTCAGATATAGCTGGAGCTACATCCTGCTTCCTTTGGGCCTGGGGCTGTGCTTGGCTTGAA
ATCTGTGTCCCCTGCCTGCACTGGCACTTTGTCCAGTCATCGGGACCTTTGGCTCAGATTTAGGGTAAGATAGGAATAGGGTACCTTTTT
CCTTTTTTTTCTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAATGCAGTGGCGTGATCTCGGCTTTACTGCAGCCTCCGCTTCCTGG
GTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGAGCGTGTGCCACGCCCGGCTAATTTTTTGTATTTTTAGTAG
AGATGGGGTTTCACCATGTTACCCAGGATGGTCTCAATATCCTGAGTTCATGATCCACCCACCTTGGCCTCCCAAAGTGCTGGGATTACA
GGCGTGAGCCACCACACCCAGCCAGTTTTCCTATTTTCTGAATTCAGAATTGACTTCTCTGGGAAAACTGGAGATGAGAATCTGCCCAGT
GCTCTGCTGTCCAGTCACCGCCTTTTGAATTTTAGTTTTGGCACCAGGAGTACCGTTAGCTTTCCCCTTCTTCTGGCCCATTTGACTCAT
CAGCACAATAGGGTCACCACCTTAACTTTTAATTTCTAATCTGCTTTACTGTCTTTAGGGTGTGTATGAAATAAACATTGACAGGCTTTC
TGGAGCCCTCAAGGTGCCTACTTTGCTGGTTCCCTTTCCAGCAGCTCCCCCACCTCCCTTAGCCCCCCCTCCTCTGGCAGCCTCTCCTGC
CTCTGCTGAGCTCCCCTCCACGTGTTCCACCCCCTTACCCTGCTGTTGTTTACATCCAACCTGCCTGAGAATTTCCTCTGGGGAGGAATC
TATTCCTGTCATGGTCTAGTGCCTGGGAGGGAGAGAACTTTCTGGGGGTAGGGTGCCCTCCATCTGAAACAGGCCAGGTGAGCATCATGC
ATAAGGCCTCCATTCTGTCCGCTCAGATTCTGGGTGGGGCCACAGGCAAATCTCCTGACTTATGGGGAGTTGGCTTGTGGTTCCTCCCTT
GGATAGCCTCCATGGAACCACTATAGGCTTTCCCAACAGCTGCCTCTGAAATAGCTGCTGCTTCGAGATCCTCCCTTTTTAAAGCACTTT
CTAAAGCCCTCAGGATGGCGGGAGCAAACAGCACTGGTATATTCTAGGAGTAAGTGCAGGAATTCAGCAGTGAGAGCATGTCTGGGACCA
CCTGGACTGCCATCCATTTAACCTCAAATCTCTTTGGGATACTCGCCCTCCCTGGGAACCAGAGTTCTGGCTCTAACATTGAGCAGCTAT
GCACTAGTTCCAGAGAAGCCACTAACAGGCTGCCATGTGTAGATGTAGGTTCTTAAGAGATCACAGGCTGGGTCATCTGATCACTGGATG
GATAGCTCAGCCTGGGGCATTTAGTGTTTTCCCTGGTGATAAATCCCCAAGGCAGCTGGATTTGGAGCTGGTGGCAAGTTGAAATTATTA

>70568_70568_5_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000428026_C10orf76_chr10_103699695_ENST00000370033_length(amino acids)=502AA_BP=380
MARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQ
SLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLDDIL
LLSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFLLQRQSGALVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPR
GAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEISVLLT
RPGDGGTGRPGPPLISRTKCAVLRLSTNAGQWKEAASKVTHALVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQ

--------------------------------------------------------------
>70568_70568_6_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000460170_C10orf76_chr10_103699695_ENST00000370033_length(transcript)=3444nt_BP=1150nt
CCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGGCAGCTGGCTGCACC
TTCGAGGAGGCAAGTGACCCAGCAGTGCCCTGCGAGTACAGCCAGGCCCAGTACGATGACTTCCAGTGGGAGCAAGTGCGAATCCACCCT
GGCACCCGGGCACCTGCGGACCTGCCCCACGGCTCCTACTTGATGGTCAACACTTCCCAGCATGCCCCAGGCCAGCGAGCCCATGTCATC
TTCCAGAGCCTGAGCGAGAATGATACCCACTGTGTGCAGTTCAGCTACTTCCTGTACAGCCGGGACGGGCACAGCCCGGGCACCCTGGGC
GTCTACGTGCGCGTTAATGGGGGCCCCCTGGGCAGTGCTGTGTGGAATATGACTGGATCCCACGGCCGTCAGTGGCACCAGGCTGAGCTG
GCTGTCAGCACTTTCTGGCCCAATGAATATCAGGTGCTGTTTGAGGCCCTCATCTCCCCAGACCGCAGGGGCTACATGGGCCTAGATGAC
ATCCTGCTTCTCAGCTACCCCTGCGCAAAGGCCCCACACTTCTCCCGCCTGGGCGACGTGGAGGTCAACGCGGGCCAGAACGCGTCGTTC
CAGTGCATGGCCGCGGGCAGAGCGGCCGAGGCCGAACGCTTCCTCTTGCAACGGCAGAGCGGGGCGCTGGTGCCGGCGGCGGGCGTGCGG
CACATCAGCCACCGGCGCTTCCTGGCCACTTTCCCGCTGGCTGCCGTGAGCCGCGCCGAGCAGGACCTGTACCGCTGTGTGTCCCAGGCC
CCGCGCGGCGCGGGCGTCTCTAACTTCGCGGAGCTCATCGTCAAGGAGCCCCCAACTCCCATCGCGCCCCCACAGCTGCTGCGTGCTGGC
CCCACCTACCTCATCATCCAGCTCAACACCAACTCCATCATTGGCGACGGGCCGATCGTGCGCAAGGAGATTGAGTACCGCATGGCGCGC
GGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAGACCTACAAGCTGTGGCACCTCGACCCCGACACAGAGTATGAGATCAGCGTGCTG
CTCACGCGTCCCGGAGACGGCGGCACTGGCCGCCCTGGGCCACCCCTCATCAGCCGCACCAAATGCGCAGTCCTGAGGCTTTCTACCAAT
GCAGGCCAGTGGAAGGAAGCAGCTAGCAAGGTGACCCATGCATTGGTTAATATCAGAGCCATCATCAACCACTTTAACCCCAAAATTGAG
TCCTACGCTGCTGTGAATCACATATCCCAACTGTCAGAGGAGCAGGTGCTGGAGGTGGTGAGAGCCAACTATGACACGCTCACGCTGAAG
CTGCAGGATGGCCTGGACCAGTATGAGCGCTACTCAGAGCAGCACAAGGAAGCTGCCTTCTTCAAAGAGCTGGTTCGATCCATTAGCACC
AACGTCCGGAGAAACCTGGCCTTCCACACACTCAGCCAAGAAGTCCTGCTCAAGGAGTTCTCCACTATCTCCTGAGGCCACGCCTACCTG
AGCAGCCTCTGACTGCCCTTACCCATGAGGATCATGGGCTGGAGGGGGAGCGAGGGGAGAGGGGGCTGCCCCCGAGGTTGGAGAGAAACA
CAGATACCAAGTTCTCTTGGTGAAGACCGCACTTCAATGGAGCTTGGGCAGCAGGGGCAGGAGGGTCAAGCCAGGGATAATCTTATTTGG
GGAGGAATGGGTGGGCACAGTGGGGAGAGGCCTCCAGGAATGTGGGGACTTCCAGAGTGGGCTCCCTAAACAGCCCCTCACATTTCCAAT
CTTGAGGTTACAAGCTGTAGCTACTGACTAATTTTCGGGAGCTGGTGAGGCAAGCCTCAGGGTAATGCCAGCACCCTGAAAGTCAGTGGC
TCTGCTCGGCTTCTGAAAACAGATCAACTCTCAGATATAGCTGGAGCTACATCCTGCTTCCTTTGGGCCTGGGGCTGTGCTTGGCTTGAA
ATCTGTGTCCCCTGCCTGCACTGGCACTTTGTCCAGTCATCGGGACCTTTGGCTCAGATTTAGGGTAAGATAGGAATAGGGTACCTTTTT
CCTTTTTTTTCTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAATGCAGTGGCGTGATCTCGGCTTTACTGCAGCCTCCGCTTCCTGG
GTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGAGCGTGTGCCACGCCCGGCTAATTTTTTGTATTTTTAGTAG
AGATGGGGTTTCACCATGTTACCCAGGATGGTCTCAATATCCTGAGTTCATGATCCACCCACCTTGGCCTCCCAAAGTGCTGGGATTACA
GGCGTGAGCCACCACACCCAGCCAGTTTTCCTATTTTCTGAATTCAGAATTGACTTCTCTGGGAAAACTGGAGATGAGAATCTGCCCAGT
GCTCTGCTGTCCAGTCACCGCCTTTTGAATTTTAGTTTTGGCACCAGGAGTACCGTTAGCTTTCCCCTTCTTCTGGCCCATTTGACTCAT
CAGCACAATAGGGTCACCACCTTAACTTTTAATTTCTAATCTGCTTTACTGTCTTTAGGGTGTGTATGAAATAAACATTGACAGGCTTTC
TGGAGCCCTCAAGGTGCCTACTTTGCTGGTTCCCTTTCCAGCAGCTCCCCCACCTCCCTTAGCCCCCCCTCCTCTGGCAGCCTCTCCTGC
CTCTGCTGAGCTCCCCTCCACGTGTTCCACCCCCTTACCCTGCTGTTGTTTACATCCAACCTGCCTGAGAATTTCCTCTGGGGAGGAATC
TATTCCTGTCATGGTCTAGTGCCTGGGAGGGAGAGAACTTTCTGGGGGTAGGGTGCCCTCCATCTGAAACAGGCCAGGTGAGCATCATGC
ATAAGGCCTCCATTCTGTCCGCTCAGATTCTGGGTGGGGCCACAGGCAAATCTCCTGACTTATGGGGAGTTGGCTTGTGGTTCCTCCCTT
GGATAGCCTCCATGGAACCACTATAGGCTTTCCCAACAGCTGCCTCTGAAATAGCTGCTGCTTCGAGATCCTCCCTTTTTAAAGCACTTT
CTAAAGCCCTCAGGATGGCGGGAGCAAACAGCACTGGTATATTCTAGGAGTAAGTGCAGGAATTCAGCAGTGAGAGCATGTCTGGGACCA
CCTGGACTGCCATCCATTTAACCTCAAATCTCTTTGGGATACTCGCCCTCCCTGGGAACCAGAGTTCTGGCTCTAACATTGAGCAGCTAT
GCACTAGTTCCAGAGAAGCCACTAACAGGCTGCCATGTGTAGATGTAGGTTCTTAAGAGATCACAGGCTGGGTCATCTGATCACTGGATG
GATAGCTCAGCCTGGGGCATTTAGTGTTTTCCCTGGTGATAAATCCCCAAGGCAGCTGGATTTGGAGCTGGTGGCAAGTTGAAATTATTA

>70568_70568_6_PTPRU-C10orf76_PTPRU_chr1_29587415_ENST00000460170_C10orf76_chr10_103699695_ENST00000370033_length(amino acids)=502AA_BP=380
MARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQ
SLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLDDIL
LLSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFLLQRQSGALVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPR
GAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEISVLLT
RPGDGGTGRPGPPLISRTKCAVLRLSTNAGQWKEAASKVTHALVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PTPRU-C10orf76


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PTPRU-C10orf76


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PTPRU-C10orf76


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource