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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:QARS-USP19 (FusionGDB2 ID:70970)

Fusion Gene Summary for QARS-USP19

check button Fusion gene summary
Fusion gene informationFusion gene name: QARS-USP19
Fusion gene ID: 70970
HgeneTgene
Gene symbol

QARS

USP19

Gene ID

5859

10869

Gene nameglutaminyl-tRNA synthetase 1ubiquitin specific peptidase 19
SynonymsGLNRS|MSCCA|PRO2195|QARSZMYND9
Cytomap

3p21.31

3p21.31

Type of geneprotein-codingprotein-coding
Descriptionglutamine--tRNA ligaseglutamine-tRNA synthetaseubiquitin carboxyl-terminal hydrolase 19deubiquitinating enzyme 19ubiquitin specific protease 19ubiquitin thioesterase 19ubiquitin thiolesterase 19ubiquitin-specific-processing protease 19zinc finger MYND domain-containing protein 9
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000306125, ENST00000414533, 
ENST00000420147, ENST00000470225, 
ENST00000488993, ENST00000398888, 
ENST00000398892, ENST00000398896, 
ENST00000398898, ENST00000417901, 
ENST00000434032, ENST00000453664, 
Fusion gene scores* DoF score4 X 6 X 3=723 X 4 X 2=24
# samples 53
** MAII scorelog2(5/72*10)=-0.526068811667588
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/24*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: QARS [Title/Abstract] AND USP19 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointQARS(49135625)-USP19(49150062), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneQARS

GO:0006425

glutaminyl-tRNA aminoacylation

24656866|26869582

HgeneQARS

GO:0006469

negative regulation of protein kinase activity

11096076

HgeneQARS

GO:0032873

negative regulation of stress-activated MAPK cascade

11096076

HgeneQARS

GO:0045892

negative regulation of transcription, DNA-templated

11096076

HgeneQARS

GO:2001234

negative regulation of apoptotic signaling pathway

11096076

TgeneUSP19

GO:0030433

ubiquitin-dependent ERAD pathway

19465887


check buttonFusion gene breakpoints across QARS (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across USP19 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AO-A0J2-01AQARSchr3

49135624

-USP19chr3

49150061

-
ChimerDB4BRCATCGA-AO-A0J2-01AQARSchr3

49135625

-USP19chr3

49150062

-


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Fusion Gene ORF analysis for QARS-USP19

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000306125ENST00000488993QARSchr3

49135624

-USP19chr3

49150061

-
5CDS-intronENST00000306125ENST00000488993QARSchr3

49135625

-USP19chr3

49150062

-
5CDS-intronENST00000414533ENST00000488993QARSchr3

49135624

-USP19chr3

49150061

-
5CDS-intronENST00000414533ENST00000488993QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000306125ENST00000398888QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000306125ENST00000398888QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000306125ENST00000398892QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000306125ENST00000398892QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000306125ENST00000398896QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000306125ENST00000398896QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000306125ENST00000398898QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000306125ENST00000398898QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000306125ENST00000417901QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000306125ENST00000417901QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000306125ENST00000434032QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000306125ENST00000434032QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000306125ENST00000453664QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000306125ENST00000453664QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000414533ENST00000398888QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000414533ENST00000398888QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000414533ENST00000398892QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000414533ENST00000398892QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000414533ENST00000398896QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000414533ENST00000398896QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000414533ENST00000398898QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000414533ENST00000398898QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000414533ENST00000417901QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000414533ENST00000417901QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000414533ENST00000434032QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000414533ENST00000434032QARSchr3

49135625

-USP19chr3

49150062

-
In-frameENST00000414533ENST00000453664QARSchr3

49135624

-USP19chr3

49150061

-
In-frameENST00000414533ENST00000453664QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000420147ENST00000398888QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000420147ENST00000398888QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000420147ENST00000398892QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000420147ENST00000398892QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000420147ENST00000398896QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000420147ENST00000398896QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000420147ENST00000398898QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000420147ENST00000398898QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000420147ENST00000417901QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000420147ENST00000417901QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000420147ENST00000434032QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000420147ENST00000434032QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000420147ENST00000453664QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000420147ENST00000453664QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000470225ENST00000398888QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000470225ENST00000398888QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000470225ENST00000398892QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000470225ENST00000398892QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000470225ENST00000398896QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000470225ENST00000398896QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000470225ENST00000398898QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000470225ENST00000398898QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000470225ENST00000417901QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000470225ENST00000417901QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000470225ENST00000434032QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000470225ENST00000434032QARSchr3

49135625

-USP19chr3

49150062

-
intron-3CDSENST00000470225ENST00000453664QARSchr3

49135624

-USP19chr3

49150061

-
intron-3CDSENST00000470225ENST00000453664QARSchr3

49135625

-USP19chr3

49150062

-
intron-intronENST00000420147ENST00000488993QARSchr3

49135624

-USP19chr3

49150061

-
intron-intronENST00000420147ENST00000488993QARSchr3

49135625

-USP19chr3

49150062

-
intron-intronENST00000470225ENST00000488993QARSchr3

49135624

-USP19chr3

49150061

-
intron-intronENST00000470225ENST00000488993QARSchr3

49135625

-USP19chr3

49150062

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for QARS-USP19


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for QARS-USP19


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:49135625/chr3:49150062)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneQARSchr3:49135624chr3:49150061ENST00000306125-2224270_280717776.0Motif'HIGH' region
HgeneQARSchr3:49135624chr3:49150061ENST00000306125-2224493_497717776.0Motif'KMSKS' region
HgeneQARSchr3:49135625chr3:49150062ENST00000306125-2224270_280717776.0Motif'HIGH' region
HgeneQARSchr3:49135625chr3:49150062ENST00000306125-2224493_497717776.0Motif'KMSKS' region
HgeneQARSchr3:49135624chr3:49150061ENST00000306125-2224271_273717776.0Nucleotide bindingATP
HgeneQARSchr3:49135624chr3:49150061ENST00000306125-2224277_283717776.0Nucleotide bindingATP
HgeneQARSchr3:49135624chr3:49150061ENST00000306125-2224486_487717776.0Nucleotide bindingATP
HgeneQARSchr3:49135624chr3:49150061ENST00000306125-2224494_496717776.0Nucleotide bindingATP
HgeneQARSchr3:49135625chr3:49150062ENST00000306125-2224271_273717776.0Nucleotide bindingATP
HgeneQARSchr3:49135625chr3:49150062ENST00000306125-2224277_283717776.0Nucleotide bindingATP
HgeneQARSchr3:49135625chr3:49150062ENST00000306125-2224486_487717776.0Nucleotide bindingATP
HgeneQARSchr3:49135625chr3:49150062ENST00000306125-2224494_496717776.0Nucleotide bindingATP
TgeneUSP19chr3:49135624chr3:49150061ENST0000039888815261313_13187321319.0Topological domainLumenal
TgeneUSP19chr3:49135624chr3:49150061ENST0000041790116271313_13188351385.0Topological domainLumenal
TgeneUSP19chr3:49135624chr3:49150061ENST0000043403216271313_13188331420.0Topological domainLumenal
TgeneUSP19chr3:49135624chr3:49150061ENST0000045366416271313_13188231373.0Topological domainLumenal
TgeneUSP19chr3:49135625chr3:49150062ENST0000039888815261313_13187321319.0Topological domainLumenal
TgeneUSP19chr3:49135625chr3:49150062ENST0000041790116271313_13188351385.0Topological domainLumenal
TgeneUSP19chr3:49135625chr3:49150062ENST0000043403216271313_13188331420.0Topological domainLumenal
TgeneUSP19chr3:49135625chr3:49150062ENST0000045366416271313_13188231373.0Topological domainLumenal
TgeneUSP19chr3:49135624chr3:49150061ENST0000039888815261292_13127321319.0TransmembraneHelical
TgeneUSP19chr3:49135624chr3:49150061ENST0000041790116271292_13128351385.0TransmembraneHelical
TgeneUSP19chr3:49135624chr3:49150061ENST0000043403216271292_13128331420.0TransmembraneHelical
TgeneUSP19chr3:49135624chr3:49150061ENST0000045366416271292_13128231373.0TransmembraneHelical
TgeneUSP19chr3:49135625chr3:49150062ENST0000039888815261292_13127321319.0TransmembraneHelical
TgeneUSP19chr3:49135625chr3:49150062ENST0000041790116271292_13128351385.0TransmembraneHelical
TgeneUSP19chr3:49135625chr3:49150062ENST0000043403216271292_13128331420.0TransmembraneHelical
TgeneUSP19chr3:49135625chr3:49150062ENST0000045366416271292_13128231373.0TransmembraneHelical
TgeneUSP19chr3:49135624chr3:49150061ENST000003988881526791_8337321319.0Zinc fingerMYND-type
TgeneUSP19chr3:49135625chr3:49150062ENST000003988881526791_8337321319.0Zinc fingerMYND-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneUSP19chr3:49135624chr3:49150061ENST000003988881526113_2027321319.0DomainCS 1
TgeneUSP19chr3:49135624chr3:49150061ENST000003988881526282_3847321319.0DomainCS 2
TgeneUSP19chr3:49135624chr3:49150061ENST000003988881526497_12147321319.0DomainNote=USP
TgeneUSP19chr3:49135624chr3:49150061ENST000004179011627113_2028351385.0DomainCS 1
TgeneUSP19chr3:49135624chr3:49150061ENST000004179011627282_3848351385.0DomainCS 2
TgeneUSP19chr3:49135624chr3:49150061ENST000004179011627497_12148351385.0DomainNote=USP
TgeneUSP19chr3:49135624chr3:49150061ENST000004340321627113_2028331420.0DomainCS 1
TgeneUSP19chr3:49135624chr3:49150061ENST000004340321627282_3848331420.0DomainCS 2
TgeneUSP19chr3:49135624chr3:49150061ENST000004340321627497_12148331420.0DomainNote=USP
TgeneUSP19chr3:49135624chr3:49150061ENST000004536641627113_2028231373.0DomainCS 1
TgeneUSP19chr3:49135624chr3:49150061ENST000004536641627282_3848231373.0DomainCS 2
TgeneUSP19chr3:49135624chr3:49150061ENST000004536641627497_12148231373.0DomainNote=USP
TgeneUSP19chr3:49135625chr3:49150062ENST000003988881526113_2027321319.0DomainCS 1
TgeneUSP19chr3:49135625chr3:49150062ENST000003988881526282_3847321319.0DomainCS 2
TgeneUSP19chr3:49135625chr3:49150062ENST000003988881526497_12147321319.0DomainNote=USP
TgeneUSP19chr3:49135625chr3:49150062ENST000004179011627113_2028351385.0DomainCS 1
TgeneUSP19chr3:49135625chr3:49150062ENST000004179011627282_3848351385.0DomainCS 2
TgeneUSP19chr3:49135625chr3:49150062ENST000004179011627497_12148351385.0DomainNote=USP
TgeneUSP19chr3:49135625chr3:49150062ENST000004340321627113_2028331420.0DomainCS 1
TgeneUSP19chr3:49135625chr3:49150062ENST000004340321627282_3848331420.0DomainCS 2
TgeneUSP19chr3:49135625chr3:49150062ENST000004340321627497_12148331420.0DomainNote=USP
TgeneUSP19chr3:49135625chr3:49150062ENST000004536641627113_2028231373.0DomainCS 1
TgeneUSP19chr3:49135625chr3:49150062ENST000004536641627282_3848231373.0DomainCS 2
TgeneUSP19chr3:49135625chr3:49150062ENST000004536641627497_12148231373.0DomainNote=USP
TgeneUSP19chr3:49135624chr3:49150061ENST0000039888815261_12917321319.0Topological domainCytoplasmic
TgeneUSP19chr3:49135624chr3:49150061ENST0000041790116271_12918351385.0Topological domainCytoplasmic
TgeneUSP19chr3:49135624chr3:49150061ENST0000043403216271_12918331420.0Topological domainCytoplasmic
TgeneUSP19chr3:49135624chr3:49150061ENST0000045366416271_12918231373.0Topological domainCytoplasmic
TgeneUSP19chr3:49135625chr3:49150062ENST0000039888815261_12917321319.0Topological domainCytoplasmic
TgeneUSP19chr3:49135625chr3:49150062ENST0000041790116271_12918351385.0Topological domainCytoplasmic
TgeneUSP19chr3:49135625chr3:49150062ENST0000043403216271_12918331420.0Topological domainCytoplasmic
TgeneUSP19chr3:49135625chr3:49150062ENST0000045366416271_12918231373.0Topological domainCytoplasmic
TgeneUSP19chr3:49135624chr3:49150061ENST000004179011627791_8338351385.0Zinc fingerMYND-type
TgeneUSP19chr3:49135624chr3:49150061ENST000004340321627791_8338331420.0Zinc fingerMYND-type
TgeneUSP19chr3:49135624chr3:49150061ENST000004536641627791_8338231373.0Zinc fingerMYND-type
TgeneUSP19chr3:49135625chr3:49150062ENST000004179011627791_8338351385.0Zinc fingerMYND-type
TgeneUSP19chr3:49135625chr3:49150062ENST000004340321627791_8338331420.0Zinc fingerMYND-type
TgeneUSP19chr3:49135625chr3:49150062ENST000004536641627791_8338231373.0Zinc fingerMYND-type


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Fusion Gene Sequence for QARS-USP19


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for QARS-USP19


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for QARS-USP19


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for QARS-USP19


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource