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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RAB11FIP5-UBE2E3 (FusionGDB2 ID:71169)

Fusion Gene Summary for RAB11FIP5-UBE2E3

check button Fusion gene summary
Fusion gene informationFusion gene name: RAB11FIP5-UBE2E3
Fusion gene ID: 71169
HgeneTgene
Gene symbol

RAB11FIP5

UBE2E3

Gene ID

26056

10477

Gene nameRAB11 family interacting protein 5ubiquitin conjugating enzyme E2 E3
SynonymsGAF1|RIP11|gaf-1|pp75|rab11-FIP5UBCH9|UbcM2
Cytomap

2p13.2

2q31.3

Type of geneprotein-codingprotein-coding
Descriptionrab11 family-interacting protein 5RAB11 family interacting protein 5 (class I)gamma-SNAP-associated factor 1phosphoprotein pp75rab11-interacting protein Rip11ubiquitin-conjugating enzyme E2 E3E2 ubiquitin-conjugating enzyme E3ubiquitin carrier protein E3ubiquitin conjugating enzyme E2E 3ubiquitin-conjugating enzyme E2-23 kDaubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)ubiquitin-conjugating e
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000258098, ENST00000493523, 
ENST00000602837, ENST00000602959, 
ENST00000602475, ENST00000602632, 
ENST00000392415, ENST00000410062, 
ENST00000602710, 
Fusion gene scores* DoF score2 X 3 X 2=1212 X 11 X 6=792
# samples 313
** MAII scorelog2(3/12*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(13/792*10)=-2.60698880705116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RAB11FIP5 [Title/Abstract] AND UBE2E3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRAB11FIP5(73303121)-UBE2E3(181925392), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRAB11FIP5

GO:0070164

negative regulation of adiponectin secretion

24040321

HgeneRAB11FIP5

GO:0071468

cellular response to acidic pH

20717956

TgeneUBE2E3

GO:0070534

protein K63-linked ubiquitination

20061386

TgeneUBE2E3

GO:0070936

protein K48-linked ubiquitination

20061386

TgeneUBE2E3

GO:0070979

protein K11-linked ubiquitination

20061386


check buttonFusion gene breakpoints across RAB11FIP5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across UBE2E3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-10-0934-01ARAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
ChimerDB4OVTCGA-10-0934RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+


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Fusion Gene ORF analysis for RAB11FIP5-UBE2E3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000258098ENST00000602837RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
5CDS-3UTRENST00000258098ENST00000602837RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
5CDS-3UTRENST00000258098ENST00000602959RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
5CDS-3UTRENST00000258098ENST00000602959RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
5CDS-intronENST00000258098ENST00000602475RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
5CDS-intronENST00000258098ENST00000602475RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
5CDS-intronENST00000258098ENST00000602632RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
5CDS-intronENST00000258098ENST00000602632RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
5UTR-3CDSENST00000493523ENST00000392415RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
5UTR-3CDSENST00000493523ENST00000392415RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
5UTR-3CDSENST00000493523ENST00000410062RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
5UTR-3CDSENST00000493523ENST00000410062RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
5UTR-3CDSENST00000493523ENST00000602710RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
5UTR-3CDSENST00000493523ENST00000602710RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
5UTR-3UTRENST00000493523ENST00000602837RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
5UTR-3UTRENST00000493523ENST00000602837RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
5UTR-3UTRENST00000493523ENST00000602959RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
5UTR-3UTRENST00000493523ENST00000602959RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
5UTR-intronENST00000493523ENST00000602475RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
5UTR-intronENST00000493523ENST00000602475RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
5UTR-intronENST00000493523ENST00000602632RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
5UTR-intronENST00000493523ENST00000602632RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
In-frameENST00000258098ENST00000392415RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
In-frameENST00000258098ENST00000392415RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
In-frameENST00000258098ENST00000410062RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
In-frameENST00000258098ENST00000410062RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+
In-frameENST00000258098ENST00000602710RAB11FIP5chr2

73303121

-UBE2E3chr2

181925392

+
In-frameENST00000258098ENST00000602710RAB11FIP5chr2

73303120

-UBE2E3chr2

181925391

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000258098RAB11FIP5chr273303121-ENST00000392415UBE2E3chr2181925392+278019991542244696
ENST00000258098RAB11FIP5chr273303121-ENST00000410062UBE2E3chr2181925392+279819991542244696
ENST00000258098RAB11FIP5chr273303121-ENST00000602710UBE2E3chr2181925392+279819991542244696
ENST00000258098RAB11FIP5chr273303120-ENST00000392415UBE2E3chr2181925391+278019991542244696
ENST00000258098RAB11FIP5chr273303120-ENST00000410062UBE2E3chr2181925391+279819991542244696
ENST00000258098RAB11FIP5chr273303120-ENST00000602710UBE2E3chr2181925391+279819991542244696

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000258098ENST00000392415RAB11FIP5chr273303121-UBE2E3chr2181925392+0.0249195640.97508043
ENST00000258098ENST00000410062RAB11FIP5chr273303121-UBE2E3chr2181925392+0.0238916320.9761084
ENST00000258098ENST00000602710RAB11FIP5chr273303121-UBE2E3chr2181925392+0.0238916320.9761084
ENST00000258098ENST00000392415RAB11FIP5chr273303120-UBE2E3chr2181925391+0.0249195640.97508043
ENST00000258098ENST00000410062RAB11FIP5chr273303120-UBE2E3chr2181925391+0.0238916320.9761084
ENST00000258098ENST00000602710RAB11FIP5chr273303120-UBE2E3chr2181925391+0.0238916320.9761084

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Fusion Genomic Features for RAB11FIP5-UBE2E3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RAB11FIP5chr273303120-UBE2E3chr2181925391+0.0121008250.98789924
RAB11FIP5chr273303120-UBE2E3chr2181925391+0.0121008250.98789924
RAB11FIP5chr273303120-UBE2E3chr2181925391+0.0121008250.98789924
RAB11FIP5chr273303120-UBE2E3chr2181925391+0.0121008250.98789924

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for RAB11FIP5-UBE2E3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:73303121/chr2:181925392)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRAB11FIP5chr2:73303120chr2:181925391ENST00000258098-455_146586654.0DomainC2
HgeneRAB11FIP5chr2:73303121chr2:181925392ENST00000258098-455_146586654.0DomainC2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRAB11FIP5chr2:73303120chr2:181925391ENST00000258098-45586_648586654.0DomainFIP-RBD
HgeneRAB11FIP5chr2:73303121chr2:181925392ENST00000258098-45586_648586654.0DomainFIP-RBD
TgeneUBE2E3chr2:73303120chr2:181925391ENST000003924153661_207126208.0DomainUBC core
TgeneUBE2E3chr2:73303120chr2:181925391ENST000004100623661_207126208.0DomainUBC core
TgeneUBE2E3chr2:73303120chr2:181925391ENST000006027103661_207126208.0DomainUBC core
TgeneUBE2E3chr2:73303120chr2:181925391ENST000006029594761_207126208.0DomainUBC core
TgeneUBE2E3chr2:73303121chr2:181925392ENST000003924153661_207126208.0DomainUBC core
TgeneUBE2E3chr2:73303121chr2:181925392ENST000004100623661_207126208.0DomainUBC core
TgeneUBE2E3chr2:73303121chr2:181925392ENST000006027103661_207126208.0DomainUBC core
TgeneUBE2E3chr2:73303121chr2:181925392ENST000006029594761_207126208.0DomainUBC core


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Fusion Gene Sequence for RAB11FIP5-UBE2E3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>71169_71169_1_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303120_ENST00000258098_UBE2E3_chr2_181925391_ENST00000392415_length(transcript)=2780nt_BP=1999nt
GCCGGTTGGGGCGGCGGGCGCGGGGCGGGGCAGGGGGCGGGGCGCTGACGTCGCGGCGCGGCCCGCGGCCAGCGGCCCGGTGAGGCGGGG
AGGCGGCGGCCGGTCGGCCCGGCCCAGCCCAGCCCGCAGCTGCGGCGGCGCTCAGAGTTGGTTCCTGACCGCCTTCTGCCGCGGCCGGGT
TTGTCACCAGGTCCTGGGGTCTGCACCGGCTCGGCCAGACCTCGCCCCCCGCTTCTCCGCCATGGCCCTGGTGCGGGGCGCGGAGCCGGC
GGCGGGGCCTTCCCGCTGGCTGCCCACGCACGTCCAGGTGACGGTGCTGCGGGCCCGCGGGCTGCGGGGCAAGAGCTCGGGAGCGGGCAG
CACCAGCGACGCGTACACGGTGATCCAGGTGGGCCGCGAGAAGTACAGTACGTCGGTGGTGGAGAAGACGCACGGCTGCCCCGAGTGGCG
TGAGGAGTGCTCCTTCGAGCTGCCGCCGGGGGCCCTGGATGGCCTGCTGCGGGCGCAGGAGGCCGACGCGGGCCCGGCGCCCTGGGCCGC
GAGCTCCGCCGCCGCCTGCGAGCTGGTGCTCACCACCATGCACCGCTCGCTCATCGGCGTCGACAAGTTCCTGGGCCAGGCCACGGTGGC
GCTGGACGAGGTCTTCGGCGCAGGCCGCGCCCAGCACACGCAGTGGTACAAGCTGCACTCCAAGCCAGGCAAGAAGGAGAAGGAACGCGG
CGAGATTGAAGTCACCATCCAGTTCACGCGCAACAACCTGAGCGCCAGTATGTTTGACCTGTCCATGAAGGACAAGCCAAGGTCTCCCTT
CAGCAAGATCAGGGACAAGATGAAGGGCAAGAAGAAGTATGATCTGGAATCTGCCTCTGCCATCCTCCCAAGCAGCGCCATAGAGGATCC
TGACCTGGGCAGCCTGGGCAAGATGGGCAAAGCCAAAGGCTTCTTCCTCCGCAACAAGCTGCGCAAGTCGTCCCTGACCCAGTCCAACAC
CTCGCTGGGCTCGGACAGCACCCTGTCCTCAGCCAGCGGGAGCTTGGCCTACCAGGGACCTGGCGCCGAACTCCTCACCCGCTCACCAAG
CCGTAGCAGCTGGCTGTCCACTGAAGGGGGCAGGGACTCTGCACAGTCCCCCAAGCTGTTCACCCATAAGAGGACCTACAGCGATGAGGC
CAACCAGATGCGAGTGGCTCCTCCTCGGGCCCTTCTGGACCTTCAGGGCCACCTGGATGCTGCCTCCCGCTCTTCGCTCTGTGTCAATGG
GAGCCACATTTACAATGAGGAGCCCCAGGGCCCTGTGCGGCACCGCAGCTCCATCTCGGGCTCGCTTCCATCCTCTGGCTCCTTGCAAGC
TGTCTCTTCCCGGTTCTCCGAGGAGGGGCCTCGTTCCACAGATGACACCTGGCCCAGAGGCAGTCGTAGCAACAGCAGCTCAGAGGCAGT
GCTTGGACAGGAGGAGCTGAGTGCTCAGGCTAAAGTCCTGGCCCCTGGGGCCAGCCACCCTGGAGAGGAGGAGGGGGCCCGGCTACCAGA
GGGCAAGCCAGTCCAGGTTGCCACACCCATAGTGGCCTCCTCTGAGGCTGTGGCAGAGAAGGAGGGAGCCCGGAAGGAGGAACGCAAGCC
CCGGATGGGTCTCTTCCACCACCACCACCAAGGCCTAAGTCGGAGCGAGTTGGGTCGCCGAAGCTCTCTGGGGGAAAAGGGGGGTCCCAT
CCTGGGGGCCTCCCCACATCACTCATCCAGTGGGGAGGAAAAGGCCAAGAGTAGCTGGTTTGGCTTGAGAGAAGCCAAGGACCCGACTCA
GAAACCCAGTCCCCACCCCGTGAAGCCCCTCAGTGCCGCCCCTGTGGAGGGCAGCCCCGACAGGAAGCAGTCCCGCTCCAGTCTGAGCAT
AGCCCTGAGCAGTGGGCTGGAGAAGCTCAAAACAGTCACATCTGGGAGCATTCAGCCTGTGACCCAGGCCCCCCAGGCTGGCCAGATGGT
GGACACCAAAAGGCTGAAGGTTACTTTCCGCACCAGAATCTATCACTGCAACATCAACAGTCAGGGAGTCATCTGTCTGGACATCCTTAA
AGACAACTGGAGTCCCGCTTTGACTATTTCAAAGGTTTTGCTGTCTATTTGTTCCCTTTTGACAGACTGCAACCCTGCGGATCCTCTGGT
TGGAAGCATAGCCACTCAGTATTTGACCAACAGAGCAGAACACGACAGGATAGCCAGACAGTGGACCAAGAGATACGCAACATAATTCAC
ATAATTTGTATGCAGTGTGAAGGAGCAGAAGGCATCTTCTCACTGTGCTGCAAATCTTTATAGCCTTTACAATACGGACTTCTGTGTATA
TGTTATACTGATTCTACTCTGCTTTTATCCTTTGGAGCCTGGGAGACTCCCCAAAAAGGTAAATGCTATCAAGAGTAGAACTTTGTAGCT
GTAGATTAGTTATGTTTAAAACGCCTACTTGCAAGTCTTGCTTCTTTGGGATATCAAAATGTATTTTGTGATGTACTAAGGATACTGGTC
CTGAAGTCTACCAAATATTATAGTGCATTTTAGCCTAATTCATTATCTGTATGAAGTTATAAAAGTAGCTGTAGATGGCTAGGAATTATG
TCATTTGTATTAAACCCAGATCTATTTCTGAGTATGTGGTTCATGCTGTTGTGAAAAATGTTTTACCTTTTACCTTTGTCAGTTTGTAAT

>71169_71169_1_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303120_ENST00000258098_UBE2E3_chr2_181925391_ENST00000392415_length(amino acids)=696AA_BP=615
MTAFCRGRVCHQVLGSAPARPDLAPRFSAMALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVE
KTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVFGAGRAQHTQWYKLHSK
PGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKLR
KSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAA
SRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPG
EEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFG
LREAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKVTFRTRIYHCNINSQ

--------------------------------------------------------------
>71169_71169_2_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303120_ENST00000258098_UBE2E3_chr2_181925391_ENST00000410062_length(transcript)=2798nt_BP=1999nt
GCCGGTTGGGGCGGCGGGCGCGGGGCGGGGCAGGGGGCGGGGCGCTGACGTCGCGGCGCGGCCCGCGGCCAGCGGCCCGGTGAGGCGGGG
AGGCGGCGGCCGGTCGGCCCGGCCCAGCCCAGCCCGCAGCTGCGGCGGCGCTCAGAGTTGGTTCCTGACCGCCTTCTGCCGCGGCCGGGT
TTGTCACCAGGTCCTGGGGTCTGCACCGGCTCGGCCAGACCTCGCCCCCCGCTTCTCCGCCATGGCCCTGGTGCGGGGCGCGGAGCCGGC
GGCGGGGCCTTCCCGCTGGCTGCCCACGCACGTCCAGGTGACGGTGCTGCGGGCCCGCGGGCTGCGGGGCAAGAGCTCGGGAGCGGGCAG
CACCAGCGACGCGTACACGGTGATCCAGGTGGGCCGCGAGAAGTACAGTACGTCGGTGGTGGAGAAGACGCACGGCTGCCCCGAGTGGCG
TGAGGAGTGCTCCTTCGAGCTGCCGCCGGGGGCCCTGGATGGCCTGCTGCGGGCGCAGGAGGCCGACGCGGGCCCGGCGCCCTGGGCCGC
GAGCTCCGCCGCCGCCTGCGAGCTGGTGCTCACCACCATGCACCGCTCGCTCATCGGCGTCGACAAGTTCCTGGGCCAGGCCACGGTGGC
GCTGGACGAGGTCTTCGGCGCAGGCCGCGCCCAGCACACGCAGTGGTACAAGCTGCACTCCAAGCCAGGCAAGAAGGAGAAGGAACGCGG
CGAGATTGAAGTCACCATCCAGTTCACGCGCAACAACCTGAGCGCCAGTATGTTTGACCTGTCCATGAAGGACAAGCCAAGGTCTCCCTT
CAGCAAGATCAGGGACAAGATGAAGGGCAAGAAGAAGTATGATCTGGAATCTGCCTCTGCCATCCTCCCAAGCAGCGCCATAGAGGATCC
TGACCTGGGCAGCCTGGGCAAGATGGGCAAAGCCAAAGGCTTCTTCCTCCGCAACAAGCTGCGCAAGTCGTCCCTGACCCAGTCCAACAC
CTCGCTGGGCTCGGACAGCACCCTGTCCTCAGCCAGCGGGAGCTTGGCCTACCAGGGACCTGGCGCCGAACTCCTCACCCGCTCACCAAG
CCGTAGCAGCTGGCTGTCCACTGAAGGGGGCAGGGACTCTGCACAGTCCCCCAAGCTGTTCACCCATAAGAGGACCTACAGCGATGAGGC
CAACCAGATGCGAGTGGCTCCTCCTCGGGCCCTTCTGGACCTTCAGGGCCACCTGGATGCTGCCTCCCGCTCTTCGCTCTGTGTCAATGG
GAGCCACATTTACAATGAGGAGCCCCAGGGCCCTGTGCGGCACCGCAGCTCCATCTCGGGCTCGCTTCCATCCTCTGGCTCCTTGCAAGC
TGTCTCTTCCCGGTTCTCCGAGGAGGGGCCTCGTTCCACAGATGACACCTGGCCCAGAGGCAGTCGTAGCAACAGCAGCTCAGAGGCAGT
GCTTGGACAGGAGGAGCTGAGTGCTCAGGCTAAAGTCCTGGCCCCTGGGGCCAGCCACCCTGGAGAGGAGGAGGGGGCCCGGCTACCAGA
GGGCAAGCCAGTCCAGGTTGCCACACCCATAGTGGCCTCCTCTGAGGCTGTGGCAGAGAAGGAGGGAGCCCGGAAGGAGGAACGCAAGCC
CCGGATGGGTCTCTTCCACCACCACCACCAAGGCCTAAGTCGGAGCGAGTTGGGTCGCCGAAGCTCTCTGGGGGAAAAGGGGGGTCCCAT
CCTGGGGGCCTCCCCACATCACTCATCCAGTGGGGAGGAAAAGGCCAAGAGTAGCTGGTTTGGCTTGAGAGAAGCCAAGGACCCGACTCA
GAAACCCAGTCCCCACCCCGTGAAGCCCCTCAGTGCCGCCCCTGTGGAGGGCAGCCCCGACAGGAAGCAGTCCCGCTCCAGTCTGAGCAT
AGCCCTGAGCAGTGGGCTGGAGAAGCTCAAAACAGTCACATCTGGGAGCATTCAGCCTGTGACCCAGGCCCCCCAGGCTGGCCAGATGGT
GGACACCAAAAGGCTGAAGGTTACTTTCCGCACCAGAATCTATCACTGCAACATCAACAGTCAGGGAGTCATCTGTCTGGACATCCTTAA
AGACAACTGGAGTCCCGCTTTGACTATTTCAAAGGTTTTGCTGTCTATTTGTTCCCTTTTGACAGACTGCAACCCTGCGGATCCTCTGGT
TGGAAGCATAGCCACTCAGTATTTGACCAACAGAGCAGAACACGACAGGATAGCCAGACAGTGGACCAAGAGATACGCAACATAATTCAC
ATAATTTGTATGCAGTGTGAAGGAGCAGAAGGCATCTTCTCACTGTGCTGCAAATCTTTATAGCCTTTACAATACGGACTTCTGTGTATA
TGTTATACTGATTCTACTCTGCTTTTATCCTTTGGAGCCTGGGAGACTCCCCAAAAAGGTAAATGCTATCAAGAGTAGAACTTTGTAGCT
GTAGATTAGTTATGTTTAAAACGCCTACTTGCAAGTCTTGCTTCTTTGGGATATCAAAATGTATTTTGTGATGTACTAAGGATACTGGTC
CTGAAGTCTACCAAATATTATAGTGCATTTTAGCCTAATTCATTATCTGTATGAAGTTATAAAAGTAGCTGTAGATGGCTAGGAATTATG
TCATTTGTATTAAACCCAGATCTATTTCTGAGTATGTGGTTCATGCTGTTGTGAAAAATGTTTTACCTTTTACCTTTGTCAGTTTGTAAT
GAGAGGATTTCCTTTTACCCTTTGTAGCTCAGAGAGCACCTGATGTATCATCTCAAACACAATAAACATGCTCCTGAAGGCATAGTTTCC

>71169_71169_2_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303120_ENST00000258098_UBE2E3_chr2_181925391_ENST00000410062_length(amino acids)=696AA_BP=615
MTAFCRGRVCHQVLGSAPARPDLAPRFSAMALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVE
KTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVFGAGRAQHTQWYKLHSK
PGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKLR
KSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAA
SRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPG
EEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFG
LREAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKVTFRTRIYHCNINSQ

--------------------------------------------------------------
>71169_71169_3_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303120_ENST00000258098_UBE2E3_chr2_181925391_ENST00000602710_length(transcript)=2798nt_BP=1999nt
GCCGGTTGGGGCGGCGGGCGCGGGGCGGGGCAGGGGGCGGGGCGCTGACGTCGCGGCGCGGCCCGCGGCCAGCGGCCCGGTGAGGCGGGG
AGGCGGCGGCCGGTCGGCCCGGCCCAGCCCAGCCCGCAGCTGCGGCGGCGCTCAGAGTTGGTTCCTGACCGCCTTCTGCCGCGGCCGGGT
TTGTCACCAGGTCCTGGGGTCTGCACCGGCTCGGCCAGACCTCGCCCCCCGCTTCTCCGCCATGGCCCTGGTGCGGGGCGCGGAGCCGGC
GGCGGGGCCTTCCCGCTGGCTGCCCACGCACGTCCAGGTGACGGTGCTGCGGGCCCGCGGGCTGCGGGGCAAGAGCTCGGGAGCGGGCAG
CACCAGCGACGCGTACACGGTGATCCAGGTGGGCCGCGAGAAGTACAGTACGTCGGTGGTGGAGAAGACGCACGGCTGCCCCGAGTGGCG
TGAGGAGTGCTCCTTCGAGCTGCCGCCGGGGGCCCTGGATGGCCTGCTGCGGGCGCAGGAGGCCGACGCGGGCCCGGCGCCCTGGGCCGC
GAGCTCCGCCGCCGCCTGCGAGCTGGTGCTCACCACCATGCACCGCTCGCTCATCGGCGTCGACAAGTTCCTGGGCCAGGCCACGGTGGC
GCTGGACGAGGTCTTCGGCGCAGGCCGCGCCCAGCACACGCAGTGGTACAAGCTGCACTCCAAGCCAGGCAAGAAGGAGAAGGAACGCGG
CGAGATTGAAGTCACCATCCAGTTCACGCGCAACAACCTGAGCGCCAGTATGTTTGACCTGTCCATGAAGGACAAGCCAAGGTCTCCCTT
CAGCAAGATCAGGGACAAGATGAAGGGCAAGAAGAAGTATGATCTGGAATCTGCCTCTGCCATCCTCCCAAGCAGCGCCATAGAGGATCC
TGACCTGGGCAGCCTGGGCAAGATGGGCAAAGCCAAAGGCTTCTTCCTCCGCAACAAGCTGCGCAAGTCGTCCCTGACCCAGTCCAACAC
CTCGCTGGGCTCGGACAGCACCCTGTCCTCAGCCAGCGGGAGCTTGGCCTACCAGGGACCTGGCGCCGAACTCCTCACCCGCTCACCAAG
CCGTAGCAGCTGGCTGTCCACTGAAGGGGGCAGGGACTCTGCACAGTCCCCCAAGCTGTTCACCCATAAGAGGACCTACAGCGATGAGGC
CAACCAGATGCGAGTGGCTCCTCCTCGGGCCCTTCTGGACCTTCAGGGCCACCTGGATGCTGCCTCCCGCTCTTCGCTCTGTGTCAATGG
GAGCCACATTTACAATGAGGAGCCCCAGGGCCCTGTGCGGCACCGCAGCTCCATCTCGGGCTCGCTTCCATCCTCTGGCTCCTTGCAAGC
TGTCTCTTCCCGGTTCTCCGAGGAGGGGCCTCGTTCCACAGATGACACCTGGCCCAGAGGCAGTCGTAGCAACAGCAGCTCAGAGGCAGT
GCTTGGACAGGAGGAGCTGAGTGCTCAGGCTAAAGTCCTGGCCCCTGGGGCCAGCCACCCTGGAGAGGAGGAGGGGGCCCGGCTACCAGA
GGGCAAGCCAGTCCAGGTTGCCACACCCATAGTGGCCTCCTCTGAGGCTGTGGCAGAGAAGGAGGGAGCCCGGAAGGAGGAACGCAAGCC
CCGGATGGGTCTCTTCCACCACCACCACCAAGGCCTAAGTCGGAGCGAGTTGGGTCGCCGAAGCTCTCTGGGGGAAAAGGGGGGTCCCAT
CCTGGGGGCCTCCCCACATCACTCATCCAGTGGGGAGGAAAAGGCCAAGAGTAGCTGGTTTGGCTTGAGAGAAGCCAAGGACCCGACTCA
GAAACCCAGTCCCCACCCCGTGAAGCCCCTCAGTGCCGCCCCTGTGGAGGGCAGCCCCGACAGGAAGCAGTCCCGCTCCAGTCTGAGCAT
AGCCCTGAGCAGTGGGCTGGAGAAGCTCAAAACAGTCACATCTGGGAGCATTCAGCCTGTGACCCAGGCCCCCCAGGCTGGCCAGATGGT
GGACACCAAAAGGCTGAAGGTTACTTTCCGCACCAGAATCTATCACTGCAACATCAACAGTCAGGGAGTCATCTGTCTGGACATCCTTAA
AGACAACTGGAGTCCCGCTTTGACTATTTCAAAGGTTTTGCTGTCTATTTGTTCCCTTTTGACAGACTGCAACCCTGCGGATCCTCTGGT
TGGAAGCATAGCCACTCAGTATTTGACCAACAGAGCAGAACACGACAGGATAGCCAGACAGTGGACCAAGAGATACGCAACATAATTCAC
ATAATTTGTATGCAGTGTGAAGGAGCAGAAGGCATCTTCTCACTGTGCTGCAAATCTTTATAGCCTTTACAATACGGACTTCTGTGTATA
TGTTATACTGATTCTACTCTGCTTTTATCCTTTGGAGCCTGGGAGACTCCCCAAAAAGGTAAATGCTATCAAGAGTAGAACTTTGTAGCT
GTAGATTAGTTATGTTTAAAACGCCTACTTGCAAGTCTTGCTTCTTTGGGATATCAAAATGTATTTTGTGATGTACTAAGGATACTGGTC
CTGAAGTCTACCAAATATTATAGTGCATTTTAGCCTAATTCATTATCTGTATGAAGTTATAAAAGTAGCTGTAGATGGCTAGGAATTATG
TCATTTGTATTAAACCCAGATCTATTTCTGAGTATGTGGTTCATGCTGTTGTGAAAAATGTTTTACCTTTTACCTTTGTCAGTTTGTAAT
GAGAGGATTTCCTTTTACCCTTTGTAGCTCAGAGAGCACCTGATGTATCATCTCAAACACAATAAACATGCTCCTGAAGGCATAGTTTCC

>71169_71169_3_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303120_ENST00000258098_UBE2E3_chr2_181925391_ENST00000602710_length(amino acids)=696AA_BP=615
MTAFCRGRVCHQVLGSAPARPDLAPRFSAMALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVE
KTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVFGAGRAQHTQWYKLHSK
PGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKLR
KSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAA
SRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPG
EEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFG
LREAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKVTFRTRIYHCNINSQ

--------------------------------------------------------------
>71169_71169_4_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303121_ENST00000258098_UBE2E3_chr2_181925392_ENST00000392415_length(transcript)=2780nt_BP=1999nt
GCCGGTTGGGGCGGCGGGCGCGGGGCGGGGCAGGGGGCGGGGCGCTGACGTCGCGGCGCGGCCCGCGGCCAGCGGCCCGGTGAGGCGGGG
AGGCGGCGGCCGGTCGGCCCGGCCCAGCCCAGCCCGCAGCTGCGGCGGCGCTCAGAGTTGGTTCCTGACCGCCTTCTGCCGCGGCCGGGT
TTGTCACCAGGTCCTGGGGTCTGCACCGGCTCGGCCAGACCTCGCCCCCCGCTTCTCCGCCATGGCCCTGGTGCGGGGCGCGGAGCCGGC
GGCGGGGCCTTCCCGCTGGCTGCCCACGCACGTCCAGGTGACGGTGCTGCGGGCCCGCGGGCTGCGGGGCAAGAGCTCGGGAGCGGGCAG
CACCAGCGACGCGTACACGGTGATCCAGGTGGGCCGCGAGAAGTACAGTACGTCGGTGGTGGAGAAGACGCACGGCTGCCCCGAGTGGCG
TGAGGAGTGCTCCTTCGAGCTGCCGCCGGGGGCCCTGGATGGCCTGCTGCGGGCGCAGGAGGCCGACGCGGGCCCGGCGCCCTGGGCCGC
GAGCTCCGCCGCCGCCTGCGAGCTGGTGCTCACCACCATGCACCGCTCGCTCATCGGCGTCGACAAGTTCCTGGGCCAGGCCACGGTGGC
GCTGGACGAGGTCTTCGGCGCAGGCCGCGCCCAGCACACGCAGTGGTACAAGCTGCACTCCAAGCCAGGCAAGAAGGAGAAGGAACGCGG
CGAGATTGAAGTCACCATCCAGTTCACGCGCAACAACCTGAGCGCCAGTATGTTTGACCTGTCCATGAAGGACAAGCCAAGGTCTCCCTT
CAGCAAGATCAGGGACAAGATGAAGGGCAAGAAGAAGTATGATCTGGAATCTGCCTCTGCCATCCTCCCAAGCAGCGCCATAGAGGATCC
TGACCTGGGCAGCCTGGGCAAGATGGGCAAAGCCAAAGGCTTCTTCCTCCGCAACAAGCTGCGCAAGTCGTCCCTGACCCAGTCCAACAC
CTCGCTGGGCTCGGACAGCACCCTGTCCTCAGCCAGCGGGAGCTTGGCCTACCAGGGACCTGGCGCCGAACTCCTCACCCGCTCACCAAG
CCGTAGCAGCTGGCTGTCCACTGAAGGGGGCAGGGACTCTGCACAGTCCCCCAAGCTGTTCACCCATAAGAGGACCTACAGCGATGAGGC
CAACCAGATGCGAGTGGCTCCTCCTCGGGCCCTTCTGGACCTTCAGGGCCACCTGGATGCTGCCTCCCGCTCTTCGCTCTGTGTCAATGG
GAGCCACATTTACAATGAGGAGCCCCAGGGCCCTGTGCGGCACCGCAGCTCCATCTCGGGCTCGCTTCCATCCTCTGGCTCCTTGCAAGC
TGTCTCTTCCCGGTTCTCCGAGGAGGGGCCTCGTTCCACAGATGACACCTGGCCCAGAGGCAGTCGTAGCAACAGCAGCTCAGAGGCAGT
GCTTGGACAGGAGGAGCTGAGTGCTCAGGCTAAAGTCCTGGCCCCTGGGGCCAGCCACCCTGGAGAGGAGGAGGGGGCCCGGCTACCAGA
GGGCAAGCCAGTCCAGGTTGCCACACCCATAGTGGCCTCCTCTGAGGCTGTGGCAGAGAAGGAGGGAGCCCGGAAGGAGGAACGCAAGCC
CCGGATGGGTCTCTTCCACCACCACCACCAAGGCCTAAGTCGGAGCGAGTTGGGTCGCCGAAGCTCTCTGGGGGAAAAGGGGGGTCCCAT
CCTGGGGGCCTCCCCACATCACTCATCCAGTGGGGAGGAAAAGGCCAAGAGTAGCTGGTTTGGCTTGAGAGAAGCCAAGGACCCGACTCA
GAAACCCAGTCCCCACCCCGTGAAGCCCCTCAGTGCCGCCCCTGTGGAGGGCAGCCCCGACAGGAAGCAGTCCCGCTCCAGTCTGAGCAT
AGCCCTGAGCAGTGGGCTGGAGAAGCTCAAAACAGTCACATCTGGGAGCATTCAGCCTGTGACCCAGGCCCCCCAGGCTGGCCAGATGGT
GGACACCAAAAGGCTGAAGGTTACTTTCCGCACCAGAATCTATCACTGCAACATCAACAGTCAGGGAGTCATCTGTCTGGACATCCTTAA
AGACAACTGGAGTCCCGCTTTGACTATTTCAAAGGTTTTGCTGTCTATTTGTTCCCTTTTGACAGACTGCAACCCTGCGGATCCTCTGGT
TGGAAGCATAGCCACTCAGTATTTGACCAACAGAGCAGAACACGACAGGATAGCCAGACAGTGGACCAAGAGATACGCAACATAATTCAC
ATAATTTGTATGCAGTGTGAAGGAGCAGAAGGCATCTTCTCACTGTGCTGCAAATCTTTATAGCCTTTACAATACGGACTTCTGTGTATA
TGTTATACTGATTCTACTCTGCTTTTATCCTTTGGAGCCTGGGAGACTCCCCAAAAAGGTAAATGCTATCAAGAGTAGAACTTTGTAGCT
GTAGATTAGTTATGTTTAAAACGCCTACTTGCAAGTCTTGCTTCTTTGGGATATCAAAATGTATTTTGTGATGTACTAAGGATACTGGTC
CTGAAGTCTACCAAATATTATAGTGCATTTTAGCCTAATTCATTATCTGTATGAAGTTATAAAAGTAGCTGTAGATGGCTAGGAATTATG
TCATTTGTATTAAACCCAGATCTATTTCTGAGTATGTGGTTCATGCTGTTGTGAAAAATGTTTTACCTTTTACCTTTGTCAGTTTGTAAT

>71169_71169_4_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303121_ENST00000258098_UBE2E3_chr2_181925392_ENST00000392415_length(amino acids)=696AA_BP=615
MTAFCRGRVCHQVLGSAPARPDLAPRFSAMALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVE
KTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVFGAGRAQHTQWYKLHSK
PGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKLR
KSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAA
SRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPG
EEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFG
LREAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKVTFRTRIYHCNINSQ

--------------------------------------------------------------
>71169_71169_5_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303121_ENST00000258098_UBE2E3_chr2_181925392_ENST00000410062_length(transcript)=2798nt_BP=1999nt
GCCGGTTGGGGCGGCGGGCGCGGGGCGGGGCAGGGGGCGGGGCGCTGACGTCGCGGCGCGGCCCGCGGCCAGCGGCCCGGTGAGGCGGGG
AGGCGGCGGCCGGTCGGCCCGGCCCAGCCCAGCCCGCAGCTGCGGCGGCGCTCAGAGTTGGTTCCTGACCGCCTTCTGCCGCGGCCGGGT
TTGTCACCAGGTCCTGGGGTCTGCACCGGCTCGGCCAGACCTCGCCCCCCGCTTCTCCGCCATGGCCCTGGTGCGGGGCGCGGAGCCGGC
GGCGGGGCCTTCCCGCTGGCTGCCCACGCACGTCCAGGTGACGGTGCTGCGGGCCCGCGGGCTGCGGGGCAAGAGCTCGGGAGCGGGCAG
CACCAGCGACGCGTACACGGTGATCCAGGTGGGCCGCGAGAAGTACAGTACGTCGGTGGTGGAGAAGACGCACGGCTGCCCCGAGTGGCG
TGAGGAGTGCTCCTTCGAGCTGCCGCCGGGGGCCCTGGATGGCCTGCTGCGGGCGCAGGAGGCCGACGCGGGCCCGGCGCCCTGGGCCGC
GAGCTCCGCCGCCGCCTGCGAGCTGGTGCTCACCACCATGCACCGCTCGCTCATCGGCGTCGACAAGTTCCTGGGCCAGGCCACGGTGGC
GCTGGACGAGGTCTTCGGCGCAGGCCGCGCCCAGCACACGCAGTGGTACAAGCTGCACTCCAAGCCAGGCAAGAAGGAGAAGGAACGCGG
CGAGATTGAAGTCACCATCCAGTTCACGCGCAACAACCTGAGCGCCAGTATGTTTGACCTGTCCATGAAGGACAAGCCAAGGTCTCCCTT
CAGCAAGATCAGGGACAAGATGAAGGGCAAGAAGAAGTATGATCTGGAATCTGCCTCTGCCATCCTCCCAAGCAGCGCCATAGAGGATCC
TGACCTGGGCAGCCTGGGCAAGATGGGCAAAGCCAAAGGCTTCTTCCTCCGCAACAAGCTGCGCAAGTCGTCCCTGACCCAGTCCAACAC
CTCGCTGGGCTCGGACAGCACCCTGTCCTCAGCCAGCGGGAGCTTGGCCTACCAGGGACCTGGCGCCGAACTCCTCACCCGCTCACCAAG
CCGTAGCAGCTGGCTGTCCACTGAAGGGGGCAGGGACTCTGCACAGTCCCCCAAGCTGTTCACCCATAAGAGGACCTACAGCGATGAGGC
CAACCAGATGCGAGTGGCTCCTCCTCGGGCCCTTCTGGACCTTCAGGGCCACCTGGATGCTGCCTCCCGCTCTTCGCTCTGTGTCAATGG
GAGCCACATTTACAATGAGGAGCCCCAGGGCCCTGTGCGGCACCGCAGCTCCATCTCGGGCTCGCTTCCATCCTCTGGCTCCTTGCAAGC
TGTCTCTTCCCGGTTCTCCGAGGAGGGGCCTCGTTCCACAGATGACACCTGGCCCAGAGGCAGTCGTAGCAACAGCAGCTCAGAGGCAGT
GCTTGGACAGGAGGAGCTGAGTGCTCAGGCTAAAGTCCTGGCCCCTGGGGCCAGCCACCCTGGAGAGGAGGAGGGGGCCCGGCTACCAGA
GGGCAAGCCAGTCCAGGTTGCCACACCCATAGTGGCCTCCTCTGAGGCTGTGGCAGAGAAGGAGGGAGCCCGGAAGGAGGAACGCAAGCC
CCGGATGGGTCTCTTCCACCACCACCACCAAGGCCTAAGTCGGAGCGAGTTGGGTCGCCGAAGCTCTCTGGGGGAAAAGGGGGGTCCCAT
CCTGGGGGCCTCCCCACATCACTCATCCAGTGGGGAGGAAAAGGCCAAGAGTAGCTGGTTTGGCTTGAGAGAAGCCAAGGACCCGACTCA
GAAACCCAGTCCCCACCCCGTGAAGCCCCTCAGTGCCGCCCCTGTGGAGGGCAGCCCCGACAGGAAGCAGTCCCGCTCCAGTCTGAGCAT
AGCCCTGAGCAGTGGGCTGGAGAAGCTCAAAACAGTCACATCTGGGAGCATTCAGCCTGTGACCCAGGCCCCCCAGGCTGGCCAGATGGT
GGACACCAAAAGGCTGAAGGTTACTTTCCGCACCAGAATCTATCACTGCAACATCAACAGTCAGGGAGTCATCTGTCTGGACATCCTTAA
AGACAACTGGAGTCCCGCTTTGACTATTTCAAAGGTTTTGCTGTCTATTTGTTCCCTTTTGACAGACTGCAACCCTGCGGATCCTCTGGT
TGGAAGCATAGCCACTCAGTATTTGACCAACAGAGCAGAACACGACAGGATAGCCAGACAGTGGACCAAGAGATACGCAACATAATTCAC
ATAATTTGTATGCAGTGTGAAGGAGCAGAAGGCATCTTCTCACTGTGCTGCAAATCTTTATAGCCTTTACAATACGGACTTCTGTGTATA
TGTTATACTGATTCTACTCTGCTTTTATCCTTTGGAGCCTGGGAGACTCCCCAAAAAGGTAAATGCTATCAAGAGTAGAACTTTGTAGCT
GTAGATTAGTTATGTTTAAAACGCCTACTTGCAAGTCTTGCTTCTTTGGGATATCAAAATGTATTTTGTGATGTACTAAGGATACTGGTC
CTGAAGTCTACCAAATATTATAGTGCATTTTAGCCTAATTCATTATCTGTATGAAGTTATAAAAGTAGCTGTAGATGGCTAGGAATTATG
TCATTTGTATTAAACCCAGATCTATTTCTGAGTATGTGGTTCATGCTGTTGTGAAAAATGTTTTACCTTTTACCTTTGTCAGTTTGTAAT
GAGAGGATTTCCTTTTACCCTTTGTAGCTCAGAGAGCACCTGATGTATCATCTCAAACACAATAAACATGCTCCTGAAGGCATAGTTTCC

>71169_71169_5_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303121_ENST00000258098_UBE2E3_chr2_181925392_ENST00000410062_length(amino acids)=696AA_BP=615
MTAFCRGRVCHQVLGSAPARPDLAPRFSAMALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVE
KTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVFGAGRAQHTQWYKLHSK
PGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKLR
KSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAA
SRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPG
EEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFG
LREAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKVTFRTRIYHCNINSQ

--------------------------------------------------------------
>71169_71169_6_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303121_ENST00000258098_UBE2E3_chr2_181925392_ENST00000602710_length(transcript)=2798nt_BP=1999nt
GCCGGTTGGGGCGGCGGGCGCGGGGCGGGGCAGGGGGCGGGGCGCTGACGTCGCGGCGCGGCCCGCGGCCAGCGGCCCGGTGAGGCGGGG
AGGCGGCGGCCGGTCGGCCCGGCCCAGCCCAGCCCGCAGCTGCGGCGGCGCTCAGAGTTGGTTCCTGACCGCCTTCTGCCGCGGCCGGGT
TTGTCACCAGGTCCTGGGGTCTGCACCGGCTCGGCCAGACCTCGCCCCCCGCTTCTCCGCCATGGCCCTGGTGCGGGGCGCGGAGCCGGC
GGCGGGGCCTTCCCGCTGGCTGCCCACGCACGTCCAGGTGACGGTGCTGCGGGCCCGCGGGCTGCGGGGCAAGAGCTCGGGAGCGGGCAG
CACCAGCGACGCGTACACGGTGATCCAGGTGGGCCGCGAGAAGTACAGTACGTCGGTGGTGGAGAAGACGCACGGCTGCCCCGAGTGGCG
TGAGGAGTGCTCCTTCGAGCTGCCGCCGGGGGCCCTGGATGGCCTGCTGCGGGCGCAGGAGGCCGACGCGGGCCCGGCGCCCTGGGCCGC
GAGCTCCGCCGCCGCCTGCGAGCTGGTGCTCACCACCATGCACCGCTCGCTCATCGGCGTCGACAAGTTCCTGGGCCAGGCCACGGTGGC
GCTGGACGAGGTCTTCGGCGCAGGCCGCGCCCAGCACACGCAGTGGTACAAGCTGCACTCCAAGCCAGGCAAGAAGGAGAAGGAACGCGG
CGAGATTGAAGTCACCATCCAGTTCACGCGCAACAACCTGAGCGCCAGTATGTTTGACCTGTCCATGAAGGACAAGCCAAGGTCTCCCTT
CAGCAAGATCAGGGACAAGATGAAGGGCAAGAAGAAGTATGATCTGGAATCTGCCTCTGCCATCCTCCCAAGCAGCGCCATAGAGGATCC
TGACCTGGGCAGCCTGGGCAAGATGGGCAAAGCCAAAGGCTTCTTCCTCCGCAACAAGCTGCGCAAGTCGTCCCTGACCCAGTCCAACAC
CTCGCTGGGCTCGGACAGCACCCTGTCCTCAGCCAGCGGGAGCTTGGCCTACCAGGGACCTGGCGCCGAACTCCTCACCCGCTCACCAAG
CCGTAGCAGCTGGCTGTCCACTGAAGGGGGCAGGGACTCTGCACAGTCCCCCAAGCTGTTCACCCATAAGAGGACCTACAGCGATGAGGC
CAACCAGATGCGAGTGGCTCCTCCTCGGGCCCTTCTGGACCTTCAGGGCCACCTGGATGCTGCCTCCCGCTCTTCGCTCTGTGTCAATGG
GAGCCACATTTACAATGAGGAGCCCCAGGGCCCTGTGCGGCACCGCAGCTCCATCTCGGGCTCGCTTCCATCCTCTGGCTCCTTGCAAGC
TGTCTCTTCCCGGTTCTCCGAGGAGGGGCCTCGTTCCACAGATGACACCTGGCCCAGAGGCAGTCGTAGCAACAGCAGCTCAGAGGCAGT
GCTTGGACAGGAGGAGCTGAGTGCTCAGGCTAAAGTCCTGGCCCCTGGGGCCAGCCACCCTGGAGAGGAGGAGGGGGCCCGGCTACCAGA
GGGCAAGCCAGTCCAGGTTGCCACACCCATAGTGGCCTCCTCTGAGGCTGTGGCAGAGAAGGAGGGAGCCCGGAAGGAGGAACGCAAGCC
CCGGATGGGTCTCTTCCACCACCACCACCAAGGCCTAAGTCGGAGCGAGTTGGGTCGCCGAAGCTCTCTGGGGGAAAAGGGGGGTCCCAT
CCTGGGGGCCTCCCCACATCACTCATCCAGTGGGGAGGAAAAGGCCAAGAGTAGCTGGTTTGGCTTGAGAGAAGCCAAGGACCCGACTCA
GAAACCCAGTCCCCACCCCGTGAAGCCCCTCAGTGCCGCCCCTGTGGAGGGCAGCCCCGACAGGAAGCAGTCCCGCTCCAGTCTGAGCAT
AGCCCTGAGCAGTGGGCTGGAGAAGCTCAAAACAGTCACATCTGGGAGCATTCAGCCTGTGACCCAGGCCCCCCAGGCTGGCCAGATGGT
GGACACCAAAAGGCTGAAGGTTACTTTCCGCACCAGAATCTATCACTGCAACATCAACAGTCAGGGAGTCATCTGTCTGGACATCCTTAA
AGACAACTGGAGTCCCGCTTTGACTATTTCAAAGGTTTTGCTGTCTATTTGTTCCCTTTTGACAGACTGCAACCCTGCGGATCCTCTGGT
TGGAAGCATAGCCACTCAGTATTTGACCAACAGAGCAGAACACGACAGGATAGCCAGACAGTGGACCAAGAGATACGCAACATAATTCAC
ATAATTTGTATGCAGTGTGAAGGAGCAGAAGGCATCTTCTCACTGTGCTGCAAATCTTTATAGCCTTTACAATACGGACTTCTGTGTATA
TGTTATACTGATTCTACTCTGCTTTTATCCTTTGGAGCCTGGGAGACTCCCCAAAAAGGTAAATGCTATCAAGAGTAGAACTTTGTAGCT
GTAGATTAGTTATGTTTAAAACGCCTACTTGCAAGTCTTGCTTCTTTGGGATATCAAAATGTATTTTGTGATGTACTAAGGATACTGGTC
CTGAAGTCTACCAAATATTATAGTGCATTTTAGCCTAATTCATTATCTGTATGAAGTTATAAAAGTAGCTGTAGATGGCTAGGAATTATG
TCATTTGTATTAAACCCAGATCTATTTCTGAGTATGTGGTTCATGCTGTTGTGAAAAATGTTTTACCTTTTACCTTTGTCAGTTTGTAAT
GAGAGGATTTCCTTTTACCCTTTGTAGCTCAGAGAGCACCTGATGTATCATCTCAAACACAATAAACATGCTCCTGAAGGCATAGTTTCC

>71169_71169_6_RAB11FIP5-UBE2E3_RAB11FIP5_chr2_73303121_ENST00000258098_UBE2E3_chr2_181925392_ENST00000602710_length(amino acids)=696AA_BP=615
MTAFCRGRVCHQVLGSAPARPDLAPRFSAMALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVE
KTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVFGAGRAQHTQWYKLHSK
PGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKLR
KSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAA
SRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPG
EEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFG
LREAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKVTFRTRIYHCNINSQ

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Fusion Gene PPI Analysis for RAB11FIP5-UBE2E3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RAB11FIP5-UBE2E3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RAB11FIP5-UBE2E3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource