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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RAB3GAP1-ACMSD (FusionGDB2 ID:71351)

Fusion Gene Summary for RAB3GAP1-ACMSD

check button Fusion gene summary
Fusion gene informationFusion gene name: RAB3GAP1-ACMSD
Fusion gene ID: 71351
HgeneTgene
Gene symbol

RAB3GAP1

ACMSD

Gene ID

22930

130013

Gene nameRAB3 GTPase activating protein catalytic subunit 1aminocarboxymuconate semialdehyde decarboxylase
SynonymsP130|RAB3GAP|RAB3GAP130|WARBM1-
Cytomap

2q21.3

2q21.3

Type of geneprotein-codingprotein-coding
Descriptionrab3 GTPase-activating protein catalytic subunitRAB3 GTPase activating protein subunit 1 (catalytic)RAB3 GTPase-activating protein 130 kDa subunitrab3-GAP p1302-amino-3-carboxymuconate-6-semialdehyde decarboxylasepicolinate carboxylase
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000487003, ENST00000264158, 
ENST00000442034, ENST00000539493, 
ENST00000425393, 		ENST00000283054, 
ENST00000356140, ENST00000392928, 
Fusion gene scores* DoF score13 X 11 X 9=12874 X 5 X 4=80
# samples 178
** MAII scorelog2(17/1287*10)=-2.920405402083
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/80*10)=0
Context

PubMed: RAB3GAP1 [Title/Abstract] AND ACMSD [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRAB3GAP1(135893502)-ACMSD(135616831), # samples:2
RAB3GAP1(135815656)-ACMSD(135655911), # samples:2
Anticipated loss of major functional domain due to fusion event.RAB3GAP1-ACMSD seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
RAB3GAP1-ACMSD seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRAB3GAP1

GO:0043087

regulation of GTPase activity

10859313

TgeneACMSD

GO:1904985

negative regulation of quinolinate biosynthetic process

12140278


check buttonFusion gene breakpoints across RAB3GAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ACMSD (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AR-A5QQ-01ARAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
ChimerDB4BRCATCGA-C8-A12Q-01ARAB3GAP1chr2

135893502

-ACMSDchr2

135616831

+
ChimerDB4BRCATCGA-C8-A12Q-01ARAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
ChimerDB4TGCTTCGA-2G-AAGA-01ARAB3GAP1chr2

135815656

-ACMSDchr2

135655911

+
ChimerDB4TGCTTCGA-2G-AAGARAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+


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Fusion Gene ORF analysis for RAB3GAP1-ACMSD

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000487003ENST00000283054RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
3UTR-3CDSENST00000487003ENST00000356140RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
3UTR-3CDSENST00000487003ENST00000356140RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
3UTR-3CDSENST00000487003ENST00000392928RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
3UTR-5UTRENST00000487003ENST00000283054RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
3UTR-5UTRENST00000487003ENST00000392928RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
5CDS-5UTRENST00000264158ENST00000283054RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
5CDS-5UTRENST00000264158ENST00000392928RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
5CDS-5UTRENST00000442034ENST00000283054RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
5CDS-5UTRENST00000442034ENST00000392928RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
5CDS-5UTRENST00000539493ENST00000283054RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
5CDS-5UTRENST00000539493ENST00000392928RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
5UTR-3CDSENST00000539493ENST00000283054RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
5UTR-3CDSENST00000539493ENST00000356140RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
5UTR-3CDSENST00000539493ENST00000392928RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
Frame-shiftENST00000264158ENST00000283054RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
Frame-shiftENST00000264158ENST00000356140RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
Frame-shiftENST00000264158ENST00000392928RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
Frame-shiftENST00000425393ENST00000283054RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
Frame-shiftENST00000425393ENST00000356140RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
Frame-shiftENST00000425393ENST00000392928RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
Frame-shiftENST00000442034ENST00000283054RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
Frame-shiftENST00000442034ENST00000356140RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
Frame-shiftENST00000442034ENST00000392928RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
Frame-shiftENST00000539493ENST00000283054RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
Frame-shiftENST00000539493ENST00000356140RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
Frame-shiftENST00000539493ENST00000392928RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
In-frameENST00000264158ENST00000283054RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
In-frameENST00000264158ENST00000356140RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
In-frameENST00000264158ENST00000356140RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
In-frameENST00000264158ENST00000392928RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
In-frameENST00000442034ENST00000283054RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
In-frameENST00000442034ENST00000356140RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
In-frameENST00000442034ENST00000356140RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
In-frameENST00000442034ENST00000392928RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
In-frameENST00000539493ENST00000356140RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
intron-3CDSENST00000425393ENST00000283054RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
intron-3CDSENST00000425393ENST00000356140RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
intron-3CDSENST00000425393ENST00000356140RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
intron-3CDSENST00000425393ENST00000392928RAB3GAP1chr2

135851263

-ACMSDchr2

135655911

+
intron-3CDSENST00000487003ENST00000283054RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
intron-3CDSENST00000487003ENST00000356140RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
intron-3CDSENST00000487003ENST00000392928RAB3GAP1chr2

135815656

+ACMSDchr2

135655911

+
intron-5UTRENST00000425393ENST00000283054RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+
intron-5UTRENST00000425393ENST00000392928RAB3GAP1chr2

135893502

+ACMSDchr2

135616831

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000264158RAB3GAP1chr2135893502+ENST00000356140ACMSDchr2135616831+30491966432874943
ENST00000539493RAB3GAP1chr2135893502+ENST00000356140ACMSDchr2135616831+328622034123111899
ENST00000442034RAB3GAP1chr2135893502+ENST00000356140ACMSDchr2135616831+30161933102841943
ENST00000264158RAB3GAP1chr2135815656+ENST00000356140ACMSDchr2135655911+52919343354103
ENST00000264158RAB3GAP1chr2135815656+ENST00000283054ACMSDchr2135655911+52519343354103
ENST00000264158RAB3GAP1chr2135815656+ENST00000392928ACMSDchr2135655911+52919343354103
ENST00000442034RAB3GAP1chr2135815656+ENST00000356140ACMSDchr2135655911+49616010321103
ENST00000442034RAB3GAP1chr2135815656+ENST00000283054ACMSDchr2135655911+49216010321103
ENST00000442034RAB3GAP1chr2135815656+ENST00000392928ACMSDchr2135655911+49616010321103

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000264158ENST00000356140RAB3GAP1chr2135893502+ACMSDchr2135616831+0.0003008690.9996991
ENST00000539493ENST00000356140RAB3GAP1chr2135893502+ACMSDchr2135616831+0.0002258440.99977416
ENST00000442034ENST00000356140RAB3GAP1chr2135893502+ACMSDchr2135616831+0.0002923970.9997075
ENST00000264158ENST00000356140RAB3GAP1chr2135815656+ACMSDchr2135655911+0.0124096460.9875903
ENST00000264158ENST00000283054RAB3GAP1chr2135815656+ACMSDchr2135655911+0.0123666810.98763335
ENST00000264158ENST00000392928RAB3GAP1chr2135815656+ACMSDchr2135655911+0.0124096460.9875903
ENST00000442034ENST00000356140RAB3GAP1chr2135815656+ACMSDchr2135655911+0.0157300070.98427
ENST00000442034ENST00000283054RAB3GAP1chr2135815656+ACMSDchr2135655911+0.0152885120.9847114
ENST00000442034ENST00000392928RAB3GAP1chr2135815656+ACMSDchr2135655911+0.0157300070.98427

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Fusion Genomic Features for RAB3GAP1-ACMSD


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RAB3GAP1chr2135815656+ACMSDchr2135655910+2.45E-050.99997556
RAB3GAP1chr2135893502+ACMSDchr2135616830+4.95E-060.999995
RAB3GAP1chr2135815656+ACMSDchr2135655910+2.45E-050.99997556
RAB3GAP1chr2135893502+ACMSDchr2135616830+4.95E-060.999995

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for RAB3GAP1-ACMSD


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:135893502/chr2:135616831)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for RAB3GAP1-ACMSD


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>71351_71351_1_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000264158_ACMSD_chr2_135655911_ENST00000283054_length(transcript)=525nt_BP=193nt
CTTCTTCCCGGCAGCCTTAGCGCCAGGCCCGGCGCTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGA
CTTCACCACTGCCTCGGAATGGGAAAGGTTTATTTCCAAAGTTGAAGAAGTCTTGAATGACTGGAAACTGATTGGAAACTCTTTGGGAAA
GCCACTCGAAAAGGATAAAGTCATTTTGGGAACCGATTACCCCTTTCCACTAGGTGAGCTGGAACCTGGGAAACTAATAGAGTCCATGGA
AGAATTTGATGAAGAAACAAAGAATAAACTCAAAGCCGGCAATGCCCTGGCATTTTTGGGTCTTGAGAGAAAACAATTTGAATGACTGAA
TTTACTACAAAGGCAAACTTTCAAAAGGATATCTCATTTTTGTTTCTAAATATGTATCAACAGGTATCAACAAAATCCTATTTTGAACTA

>71351_71351_1_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000264158_ACMSD_chr2_135655911_ENST00000283054_length(amino acids)=103AA_BP=50
MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGNSLGKPLEKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGN

--------------------------------------------------------------
>71351_71351_2_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000264158_ACMSD_chr2_135655911_ENST00000356140_length(transcript)=529nt_BP=193nt
CTTCTTCCCGGCAGCCTTAGCGCCAGGCCCGGCGCTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGA
CTTCACCACTGCCTCGGAATGGGAAAGGTTTATTTCCAAAGTTGAAGAAGTCTTGAATGACTGGAAACTGATTGGAAACTCTTTGGGAAA
GCCACTCGAAAAGGATAAAGTCATTTTGGGAACCGATTACCCCTTTCCACTAGGTGAGCTGGAACCTGGGAAACTAATAGAGTCCATGGA
AGAATTTGATGAAGAAACAAAGAATAAACTCAAAGCCGGCAATGCCCTGGCATTTTTGGGTCTTGAGAGAAAACAATTTGAATGACTGAA
TTTACTACAAAGGCAAACTTTCAAAAGGATATCTCATTTTTGTTTCTAAATATGTATCAACAGGTATCAACAAAATCCTATTTTGAACTA

>71351_71351_2_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000264158_ACMSD_chr2_135655911_ENST00000356140_length(amino acids)=103AA_BP=50
MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGNSLGKPLEKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGN

--------------------------------------------------------------
>71351_71351_3_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000264158_ACMSD_chr2_135655911_ENST00000392928_length(transcript)=529nt_BP=193nt
CTTCTTCCCGGCAGCCTTAGCGCCAGGCCCGGCGCTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGA
CTTCACCACTGCCTCGGAATGGGAAAGGTTTATTTCCAAAGTTGAAGAAGTCTTGAATGACTGGAAACTGATTGGAAACTCTTTGGGAAA
GCCACTCGAAAAGGATAAAGTCATTTTGGGAACCGATTACCCCTTTCCACTAGGTGAGCTGGAACCTGGGAAACTAATAGAGTCCATGGA
AGAATTTGATGAAGAAACAAAGAATAAACTCAAAGCCGGCAATGCCCTGGCATTTTTGGGTCTTGAGAGAAAACAATTTGAATGACTGAA
TTTACTACAAAGGCAAACTTTCAAAAGGATATCTCATTTTTGTTTCTAAATATGTATCAACAGGTATCAACAAAATCCTATTTTGAACTA

>71351_71351_3_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000264158_ACMSD_chr2_135655911_ENST00000392928_length(amino acids)=103AA_BP=50
MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGNSLGKPLEKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGN

--------------------------------------------------------------
>71351_71351_4_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000442034_ACMSD_chr2_135655911_ENST00000283054_length(transcript)=492nt_BP=160nt
GCTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGACTTCACCACTGCCTCGGAATGGGAAAGGTTTAT
TTCCAAAGTTGAAGAAGTCTTGAATGACTGGAAACTGATTGGAAACTCTTTGGGAAAGCCACTCGAAAAGGATAAAGTCATTTTGGGAAC
CGATTACCCCTTTCCACTAGGTGAGCTGGAACCTGGGAAACTAATAGAGTCCATGGAAGAATTTGATGAAGAAACAAAGAATAAACTCAA
AGCCGGCAATGCCCTGGCATTTTTGGGTCTTGAGAGAAAACAATTTGAATGACTGAATTTACTACAAAGGCAAACTTTCAAAAGGATATC
TCATTTTTGTTTCTAAATATGTATCAACAGGTATCAACAAAATCCTATTTTGAACTATTTTACTCAGAAATGAATGTCCCAAATATCCTA

>71351_71351_4_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000442034_ACMSD_chr2_135655911_ENST00000283054_length(amino acids)=103AA_BP=50
MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGNSLGKPLEKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGN

--------------------------------------------------------------
>71351_71351_5_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000442034_ACMSD_chr2_135655911_ENST00000356140_length(transcript)=496nt_BP=160nt
GCTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGACTTCACCACTGCCTCGGAATGGGAAAGGTTTAT
TTCCAAAGTTGAAGAAGTCTTGAATGACTGGAAACTGATTGGAAACTCTTTGGGAAAGCCACTCGAAAAGGATAAAGTCATTTTGGGAAC
CGATTACCCCTTTCCACTAGGTGAGCTGGAACCTGGGAAACTAATAGAGTCCATGGAAGAATTTGATGAAGAAACAAAGAATAAACTCAA
AGCCGGCAATGCCCTGGCATTTTTGGGTCTTGAGAGAAAACAATTTGAATGACTGAATTTACTACAAAGGCAAACTTTCAAAAGGATATC
TCATTTTTGTTTCTAAATATGTATCAACAGGTATCAACAAAATCCTATTTTGAACTATTTTACTCAGAAATGAATGTCCCAAATATCCTA

>71351_71351_5_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000442034_ACMSD_chr2_135655911_ENST00000356140_length(amino acids)=103AA_BP=50
MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGNSLGKPLEKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGN

--------------------------------------------------------------
>71351_71351_6_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000442034_ACMSD_chr2_135655911_ENST00000392928_length(transcript)=496nt_BP=160nt
GCTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGACTTCACCACTGCCTCGGAATGGGAAAGGTTTAT
TTCCAAAGTTGAAGAAGTCTTGAATGACTGGAAACTGATTGGAAACTCTTTGGGAAAGCCACTCGAAAAGGATAAAGTCATTTTGGGAAC
CGATTACCCCTTTCCACTAGGTGAGCTGGAACCTGGGAAACTAATAGAGTCCATGGAAGAATTTGATGAAGAAACAAAGAATAAACTCAA
AGCCGGCAATGCCCTGGCATTTTTGGGTCTTGAGAGAAAACAATTTGAATGACTGAATTTACTACAAAGGCAAACTTTCAAAAGGATATC
TCATTTTTGTTTCTAAATATGTATCAACAGGTATCAACAAAATCCTATTTTGAACTATTTTACTCAGAAATGAATGTCCCAAATATCCTA

>71351_71351_6_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135815656_ENST00000442034_ACMSD_chr2_135655911_ENST00000392928_length(amino acids)=103AA_BP=50
MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGNSLGKPLEKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGN

--------------------------------------------------------------
>71351_71351_7_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135893502_ENST00000264158_ACMSD_chr2_135616831_ENST00000356140_length(transcript)=3049nt_BP=1966nt
CTTCTTCCCGGCAGCCTTAGCGCCAGGCCCGGCGCTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGA
CTTCACCACTGCCTCGGAATGGGAAAGGTTTATTTCCAAAGTTGAAGAAGTCTTGAATGACTGGAAACTGATTGGAAACTCTTTGGGAAA
GCCACTCGAAAAGGGTATATTTACTTCTGGCACATGGGAAGAGAAATCAGATGAAATTTCCTTTGCTGACTTCAAGTTCTCAGTCACTCA
TCATTATCTTGTACAAGAGTCCACTGATAAAGAAGGAAAGGATGAGTTATTAGAGGATGTTGTTCCACAATCTATGCAAGATTTGCTGGG
TATGAATAATGACTTTCCTCCAAGAGCACATTGCCTGGTAAGATGGTATGGGCTACGTGAGTTCGTGGTGATTGCCCCTGCTGCACACAG
TGACGCTGTTCTCAGCGAATCTAAGTGCAACCTTCTTCTGAGTTCTGTTTCTATTGCCTTGGGAAACACTGGCTGTCAGGTGCCACTCTT
TGTGCAAATTCACCACAAATGGCGAAGAATGTATGTAGGAGAATGTCAAGGTCCTGGTGTACGAACTGATTTCGAAATGGTTCATCTTAG
AAAAGTGCCAAATCAGTACACTCACTTATCAGGTCTGCTGGATATCTTCAAATCAAAGATTGGATGTCCTTTAACTCCATTGCCTCCAGT
TAGTATTGCTATTCGATTTACCTATGTACTTCAAGATTGGCAGCAGTATTTTTGGCCTCAGCAACCTCCAGACATAGATGCCCTTGTAGG
AGGAGAAGTTGGAGGCTTGGAGTTTGGCAAGTTACCATTTGGTGCCTGCGAAGATCCTATTAGTGAACTCCATTTAGCTACTACATGGCC
TCATCTGACCGAAGGGATCATTGTGGATAATGATGTTTATTCTGATTTGGATCCTATTCAAGCTCCACATTGGTCTGTTAGAGTTCGAAA
AGCTGAGAATCCTCAGTGTTTGCTAGGTGATTTTGTCACTGAATTTTTTAAAATTTGCCGTCGAAAGGAGTCAACTGATGAGATTCTTGG
ACGATCTGCATTTGAGGAAGAAGGCAAAGAAACTGCTGATATAACTCATGCTTTGTCAAAATTGACAGAGCCGGCATCAGTTCCAATTCA
TAAATTATCAGTTTCAAATATGGTACACACTGCAAAGAAGAAAATCCGAAAACACAGAGGTGTAGAGGAGTCACCGCTAAATAATGATGT
TCTTAATACTATTCTCCTGTTCTTATTCCCTGATGCTGTTTCTGAGAAACCATTAGATGGAACTACTTCAACAGATAATAATAATCCTCC
ATCAGAGAGTGAAGACTATAATCTCTACAATCAGTTCAAGTCTGCACCATCTGACAGTTTAACATACAAACTGGCTTTGTGTCTCTGTAT
GATCAATTTTTACCATGGAGGGTTGAAAGGAGTGGCACACCTCTGGCAGGAATTTGTTCTTGAAATGCGTTTCCGATGGGAAAACAACTT
TCTGATTCCAGGATTAGCAAGTGGACCCCCAGATCTGAGGTGTTGTTTACTGCATCAGAAACTACAGATGTTAAATTGTTGTATTGAAAG
AAAGAAGGCACGTGATGAGGGGAAAAAGACAAGTGCTTCAGATGTCACTAATATATATCCAGGGGATGCTGGAAAAGCAGGAGACCAGTT
GGTGCCAGATAATCTAAAAGAAACAGATAAGGAAAAGGGAGAGGTAGGAAAATCTTGGGATTCCTGGAGTGACAGCGAAGAAGAATTTTT
TGAATGCCTAAGTGATACTGAAGAACTTAAAGGAAATGGACAAGAGAGTGGCAAGAAAGGAGGACCTAAGGAGATGGCAAATTTAAGGCC
GGAAGGACGGCTCTATCAGCATGGGAAACTTACACTGCTGCATAATGGAGAACCTCTCTACATTCCAGTAACCCAGGGAGAAGCAAAGTT
GTTGAAAGATGGGAAAGTCTTCAGAGTGGTGCGAGAGAATTGCTGGGATCCAGAAGTTCGTATTAGAGAAATGGACCAAAAAGGAGTAAC
AGTGCAAGCCCTTTCCACAGTTCCTGTCATGTTTAGCTACTGGGCCAAACCTGAGGACACTTTAAACCTGTGCCAGCTTTTAAACAACGA
CCTTGCCAGCACCGTTGTGAGCTACCCCAGGAGGTTCGTGGGTCTGGGGACGTTGCCCATGCAGGCCCCTGAGCTGGCGGTCAAGGAGAT
GGAGCGCTGTGTGAAAGAGCTGGGCTTTCCCGGGGTCCAAATTGGCACCCACGTCAACGAGTGGGACCTGAACGCGCAGGAGCTCTTTCC
TGTCTATGCGGCAGCCGAAAGGCTGAAGTGTTCCCTGTTCGTGCATCCCTGGGACATGCAGATGGATGGACGAATGGCCAAATACTGGCT
CCCTTGGCTTGTAGGAATGCCAGCAGAGACCACCATAGCCATTTGCTCCATGATCATGGGTGGAGTATTTGAGAAGTTTCCCAAACTGAA
AGTGTGTTTCGCACATGGTGGTGGTGCCTTCCCCTTCACAGTGGGAAGAATCTCCCATGGATTCAGCATGCGCCCAGATCTGTGTGCCCA
GGACAACCCCATGAACCCGAAGAAATACCTTGGTTCCTTTTACACAGATGCTTTGGTTCATGATCCTCTGTCCCTCAAGCTGTTAACAGA
TGTCATAGGAAAGGATAAAGTCATTTTGGGAACCGATTACCCCTTTCCACTAGGTGAGCTGGAACCTGGGAAACTAATAGAGTCCATGGA
AGAATTTGATGAAGAAACAAAGAATAAACTCAAAGCCGGCAATGCCCTGGCATTTTTGGGTCTTGAGAGAAAACAATTTGAATGACTGAA
TTTACTACAAAGGCAAACTTTCAAAAGGATATCTCATTTTTGTTTCTAAATATGTATCAACAGGTATCAACAAAATCCTATTTTGAACTA

>71351_71351_7_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135893502_ENST00000264158_ACMSD_chr2_135616831_ENST00000356140_length(amino acids)=943AA_BP=640
MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGNSLGKPLEKGIFTSGTWEEKSDEISFADFKFSVTHHYLVQESTDKEGKD
ELLEDVVPQSMQDLLGMNNDFPPRAHCLVRWYGLREFVVIAPAAHSDAVLSESKCNLLLSSVSIALGNTGCQVPLFVQIHHKWRRMYVGE
CQGPGVRTDFEMVHLRKVPNQYTHLSGLLDIFKSKIGCPLTPLPPVSIAIRFTYVLQDWQQYFWPQQPPDIDALVGGEVGGLEFGKLPFG
ACEDPISELHLATTWPHLTEGIIVDNDVYSDLDPIQAPHWSVRVRKAENPQCLLGDFVTEFFKICRRKESTDEILGRSAFEEEGKETADI
THALSKLTEPASVPIHKLSVSNMVHTAKKKIRKHRGVEESPLNNDVLNTILLFLFPDAVSEKPLDGTTSTDNNNPPSESEDYNLYNQFKS
APSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWENNFLIPGLASGPPDLRCCLLHQKLQMLNCCIERKKARDEGKKTSASD
VTNIYPGDAGKAGDQLVPDNLKETDKEKGEVGKSWDSWSDSEEEFFECLSDTEELKGNGQESGKKGGPKEMANLRPEGRLYQHGKLTLLH
NGEPLYIPVTQGEAKLLKDGKVFRVVRENCWDPEVRIREMDQKGVTVQALSTVPVMFSYWAKPEDTLNLCQLLNNDLASTVVSYPRRFVG
LGTLPMQAPELAVKEMERCVKELGFPGVQIGTHVNEWDLNAQELFPVYAAAERLKCSLFVHPWDMQMDGRMAKYWLPWLVGMPAETTIAI
CSMIMGGVFEKFPKLKVCFAHGGGAFPFTVGRISHGFSMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDVIGKDKVILGTDYP

--------------------------------------------------------------
>71351_71351_8_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135893502_ENST00000442034_ACMSD_chr2_135616831_ENST00000356140_length(transcript)=3016nt_BP=1933nt
GCTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGACTTCACCACTGCCTCGGAATGGGAAAGGTTTAT
TTCCAAAGTTGAAGAAGTCTTGAATGACTGGAAACTGATTGGAAACTCTTTGGGAAAGCCACTCGAAAAGGGTATATTTACTTCTGGCAC
ATGGGAAGAGAAATCAGATGAAATTTCCTTTGCTGACTTCAAGTTCTCAGTCACTCATCATTATCTTGTACAAGAGTCCACTGATAAAGA
AGGAAAGGATGAGTTATTAGAGGATGTTGTTCCACAATCTATGCAAGATTTGCTGGGTATGAATAATGACTTTCCTCCAAGAGCACATTG
CCTGGTAAGATGGTATGGGCTACGTGAGTTCGTGGTGATTGCCCCTGCTGCACACAGTGACGCTGTTCTCAGCGAATCTAAGTGCAACCT
TCTTCTGAGTTCTGTTTCTATTGCCTTGGGAAACACTGGCTGTCAGGTGCCACTCTTTGTGCAAATTCACCACAAATGGCGAAGAATGTA
TGTAGGAGAATGTCAAGGTCCTGGTGTACGAACTGATTTCGAAATGGTTCATCTTAGAAAAGTGCCAAATCAGTACACTCACTTATCAGG
TCTGCTGGATATCTTCAAATCAAAGATTGGATGTCCTTTAACTCCATTGCCTCCAGTTAGTATTGCTATTCGATTTACCTATGTACTTCA
AGATTGGCAGCAGTATTTTTGGCCTCAGCAACCTCCAGACATAGATGCCCTTGTAGGAGGAGAAGTTGGAGGCTTGGAGTTTGGCAAGTT
ACCATTTGGTGCCTGCGAAGATCCTATTAGTGAACTCCATTTAGCTACTACATGGCCTCATCTGACCGAAGGGATCATTGTGGATAATGA
TGTTTATTCTGATTTGGATCCTATTCAAGCTCCACATTGGTCTGTTAGAGTTCGAAAAGCTGAGAATCCTCAGTGTTTGCTAGGTGATTT
TGTCACTGAATTTTTTAAAATTTGCCGTCGAAAGGAGTCAACTGATGAGATTCTTGGACGATCTGCATTTGAGGAAGAAGGCAAAGAAAC
TGCTGATATAACTCATGCTTTGTCAAAATTGACAGAGCCGGCATCAGTTCCAATTCATAAATTATCAGTTTCAAATATGGTACACACTGC
AAAGAAGAAAATCCGAAAACACAGAGGTGTAGAGGAGTCACCGCTAAATAATGATGTTCTTAATACTATTCTCCTGTTCTTATTCCCTGA
TGCTGTTTCTGAGAAACCATTAGATGGAACTACTTCAACAGATAATAATAATCCTCCATCAGAGAGTGAAGACTATAATCTCTACAATCA
GTTCAAGTCTGCACCATCTGACAGTTTAACATACAAACTGGCTTTGTGTCTCTGTATGATCAATTTTTACCATGGAGGGTTGAAAGGAGT
GGCACACCTCTGGCAGGAATTTGTTCTTGAAATGCGTTTCCGATGGGAAAACAACTTTCTGATTCCAGGATTAGCAAGTGGACCCCCAGA
TCTGAGGTGTTGTTTACTGCATCAGAAACTACAGATGTTAAATTGTTGTATTGAAAGAAAGAAGGCACGTGATGAGGGGAAAAAGACAAG
TGCTTCAGATGTCACTAATATATATCCAGGGGATGCTGGAAAAGCAGGAGACCAGTTGGTGCCAGATAATCTAAAAGAAACAGATAAGGA
AAAGGGAGAGGTAGGAAAATCTTGGGATTCCTGGAGTGACAGCGAAGAAGAATTTTTTGAATGCCTAAGTGATACTGAAGAACTTAAAGG
AAATGGACAAGAGAGTGGCAAGAAAGGAGGACCTAAGGAGATGGCAAATTTAAGGCCGGAAGGACGGCTCTATCAGCATGGGAAACTTAC
ACTGCTGCATAATGGAGAACCTCTCTACATTCCAGTAACCCAGGGAGAAGCAAAGTTGTTGAAAGATGGGAAAGTCTTCAGAGTGGTGCG
AGAGAATTGCTGGGATCCAGAAGTTCGTATTAGAGAAATGGACCAAAAAGGAGTAACAGTGCAAGCCCTTTCCACAGTTCCTGTCATGTT
TAGCTACTGGGCCAAACCTGAGGACACTTTAAACCTGTGCCAGCTTTTAAACAACGACCTTGCCAGCACCGTTGTGAGCTACCCCAGGAG
GTTCGTGGGTCTGGGGACGTTGCCCATGCAGGCCCCTGAGCTGGCGGTCAAGGAGATGGAGCGCTGTGTGAAAGAGCTGGGCTTTCCCGG
GGTCCAAATTGGCACCCACGTCAACGAGTGGGACCTGAACGCGCAGGAGCTCTTTCCTGTCTATGCGGCAGCCGAAAGGCTGAAGTGTTC
CCTGTTCGTGCATCCCTGGGACATGCAGATGGATGGACGAATGGCCAAATACTGGCTCCCTTGGCTTGTAGGAATGCCAGCAGAGACCAC
CATAGCCATTTGCTCCATGATCATGGGTGGAGTATTTGAGAAGTTTCCCAAACTGAAAGTGTGTTTCGCACATGGTGGTGGTGCCTTCCC
CTTCACAGTGGGAAGAATCTCCCATGGATTCAGCATGCGCCCAGATCTGTGTGCCCAGGACAACCCCATGAACCCGAAGAAATACCTTGG
TTCCTTTTACACAGATGCTTTGGTTCATGATCCTCTGTCCCTCAAGCTGTTAACAGATGTCATAGGAAAGGATAAAGTCATTTTGGGAAC
CGATTACCCCTTTCCACTAGGTGAGCTGGAACCTGGGAAACTAATAGAGTCCATGGAAGAATTTGATGAAGAAACAAAGAATAAACTCAA
AGCCGGCAATGCCCTGGCATTTTTGGGTCTTGAGAGAAAACAATTTGAATGACTGAATTTACTACAAAGGCAAACTTTCAAAAGGATATC
TCATTTTTGTTTCTAAATATGTATCAACAGGTATCAACAAAATCCTATTTTGAACTATTTTACTCAGAAATGAATGTCCCAAATATCCTA

>71351_71351_8_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135893502_ENST00000442034_ACMSD_chr2_135616831_ENST00000356140_length(amino acids)=943AA_BP=640
MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGNSLGKPLEKGIFTSGTWEEKSDEISFADFKFSVTHHYLVQESTDKEGKD
ELLEDVVPQSMQDLLGMNNDFPPRAHCLVRWYGLREFVVIAPAAHSDAVLSESKCNLLLSSVSIALGNTGCQVPLFVQIHHKWRRMYVGE
CQGPGVRTDFEMVHLRKVPNQYTHLSGLLDIFKSKIGCPLTPLPPVSIAIRFTYVLQDWQQYFWPQQPPDIDALVGGEVGGLEFGKLPFG
ACEDPISELHLATTWPHLTEGIIVDNDVYSDLDPIQAPHWSVRVRKAENPQCLLGDFVTEFFKICRRKESTDEILGRSAFEEEGKETADI
THALSKLTEPASVPIHKLSVSNMVHTAKKKIRKHRGVEESPLNNDVLNTILLFLFPDAVSEKPLDGTTSTDNNNPPSESEDYNLYNQFKS
APSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWENNFLIPGLASGPPDLRCCLLHQKLQMLNCCIERKKARDEGKKTSASD
VTNIYPGDAGKAGDQLVPDNLKETDKEKGEVGKSWDSWSDSEEEFFECLSDTEELKGNGQESGKKGGPKEMANLRPEGRLYQHGKLTLLH
NGEPLYIPVTQGEAKLLKDGKVFRVVRENCWDPEVRIREMDQKGVTVQALSTVPVMFSYWAKPEDTLNLCQLLNNDLASTVVSYPRRFVG
LGTLPMQAPELAVKEMERCVKELGFPGVQIGTHVNEWDLNAQELFPVYAAAERLKCSLFVHPWDMQMDGRMAKYWLPWLVGMPAETTIAI
CSMIMGGVFEKFPKLKVCFAHGGGAFPFTVGRISHGFSMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDVIGKDKVILGTDYP

--------------------------------------------------------------
>71351_71351_9_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135893502_ENST00000539493_ACMSD_chr2_135616831_ENST00000356140_length(transcript)=3286nt_BP=2203nt
GGCGCTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGACTTCACCACTGCCTCGGAATGGGAAAGGTT
TATTTCCAAAGTTGAAGAAGTCTTGAATGACTGGAAACTGATTGGAAACTCTTTGGGAAAGCCACTCGAAAAGAACAACTTTTAACAGTT
CCATGTGTGCACATTATACCTTGAAAAAAAGTGTTCACAACAGCGAAGACTTGAAACCAACCCAAATGTCCATCAATGACAGACTGGATT
AAGAAAATGTGGCACATATAAACCATGGAATACTATGCAGCCATAAAAAAGGATGAGTTCATGTCCTTTGTAGGGACATGGATGAAGCTG
GAAACCATCATTCTCAGCACTCTTAACACGGGAACAGAAAACCAAATGCTGCATGTTCTCACTCATAAGTGGTATATTTACTTCTGGCAC
ATGGGAAGAGAAATCAGATGAAATTTCCTTTGCTGACTTCAAGTTCTCAGTCACTCATCATTATCTTGTACAAGAGTCCACTGATAAAGA
AGGAAAGGATGAGTTATTAGAGGATGTTGTTCCACAATCTATGCAAGATTTGCTGGGTATGAATAATGACTTTCCTCCAAGAGCACATTG
CCTGGTAAGATGGTATGGGCTACGTGAGTTCGTGGTGATTGCCCCTGCTGCACACAGTGACGCTGTTCTCAGCGAATCTAAGTGCAACCT
TCTTCTGAGTTCTGTTTCTATTGCCTTGGGAAACACTGGCTGTCAGGTGCCACTCTTTGTGCAAATTCACCACAAATGGCGAAGAATGTA
TGTAGGAGAATGTCAAGGTCCTGGTGTACGAACTGATTTCGAAATGGTTCATCTTAGAAAAGTGCCAAATCAGTACACTCACTTATCAGG
TCTGCTGGATATCTTCAAATCAAAGATTGGATGTCCTTTAACTCCATTGCCTCCAGTTAGTATTGCTATTCGATTTACCTATGTACTTCA
AGATTGGCAGCAGTATTTTTGGCCTCAGCAACCTCCAGACATAGATGCCCTTGTAGGAGGAGAAGTTGGAGGCTTGGAGTTTGGCAAGTT
ACCATTTGGTGCCTGCGAAGATCCTATTAGTGAACTCCATTTAGCTACTACATGGCCTCATCTGACCGAAGGGATCATTGTGGATAATGA
TGTTTATTCTGATTTGGATCCTATTCAAGCTCCACATTGGTCTGTTAGAGTTCGAAAAGCTGAGAATCCTCAGTGTTTGCTAGGTGATTT
TGTCACTGAATTTTTTAAAATTTGCCGTCGAAAGGAGTCAACTGATGAGATTCTTGGACGATCTGCATTTGAGGAAGAAGGCAAAGAAAC
TGCTGATATAACTCATGCTTTGTCAAAATTGACAGAGCCGGCATCAGTTCCAATTCATAAATTATCAGTTTCAAATATGGTACACACTGC
AAAGAAGAAAATCCGAAAACACAGAGGTGTAGAGGAGTCACCGCTAAATAATGATGTTCTTAATACTATTCTCCTGTTCTTATTCCCTGA
TGCTGTTTCTGAGAAACCATTAGATGGAACTACTTCAACAGATAATAATAATCCTCCATCAGAGAGTGAAGACTATAATCTCTACAATCA
GTTCAAGTCTGCACCATCTGACAGTTTAACATACAAACTGGCTTTGTGTCTCTGTATGATCAATTTTTACCATGGAGGGTTGAAAGGAGT
GGCACACCTCTGGCAGGAATTTGTTCTTGAAATGCGTTTCCGATGGGAAAACAACTTTCTGATTCCAGGATTAGCAAGTGGACCCCCAGA
TCTGAGGTGTTGTTTACTGCATCAGAAACTACAGATGTTAAATTGTTGTATTGAAAGAAAGAAGGCACGTGATGAGGGGAAAAAGACAAG
TGCTTCAGATGTCACTAATATATATCCAGGGGATGCTGGAAAAGCAGGAGACCAGTTGGTGCCAGATAATCTAAAAGAAACAGATAAGGA
AAAGGGAGAGGTAGGAAAATCTTGGGATTCCTGGAGTGACAGCGAAGAAGAATTTTTTGAATGCCTAAGTGATACTGAAGAACTTAAAGG
AAATGGACAAGAGAGTGGCAAGAAAGGAGGACCTAAGGAGATGGCAAATTTAAGGCCGGAAGGACGGCTCTATCAGCATGGGAAACTTAC
ACTGCTGCATAATGGAGAACCTCTCTACATTCCAGTAACCCAGGGAGAAGCAAAGTTGTTGAAAGATGGGAAAGTCTTCAGAGTGGTGCG
AGAGAATTGCTGGGATCCAGAAGTTCGTATTAGAGAAATGGACCAAAAAGGAGTAACAGTGCAAGCCCTTTCCACAGTTCCTGTCATGTT
TAGCTACTGGGCCAAACCTGAGGACACTTTAAACCTGTGCCAGCTTTTAAACAACGACCTTGCCAGCACCGTTGTGAGCTACCCCAGGAG
GTTCGTGGGTCTGGGGACGTTGCCCATGCAGGCCCCTGAGCTGGCGGTCAAGGAGATGGAGCGCTGTGTGAAAGAGCTGGGCTTTCCCGG
GGTCCAAATTGGCACCCACGTCAACGAGTGGGACCTGAACGCGCAGGAGCTCTTTCCTGTCTATGCGGCAGCCGAAAGGCTGAAGTGTTC
CCTGTTCGTGCATCCCTGGGACATGCAGATGGATGGACGAATGGCCAAATACTGGCTCCCTTGGCTTGTAGGAATGCCAGCAGAGACCAC
CATAGCCATTTGCTCCATGATCATGGGTGGAGTATTTGAGAAGTTTCCCAAACTGAAAGTGTGTTTCGCACATGGTGGTGGTGCCTTCCC
CTTCACAGTGGGAAGAATCTCCCATGGATTCAGCATGCGCCCAGATCTGTGTGCCCAGGACAACCCCATGAACCCGAAGAAATACCTTGG
TTCCTTTTACACAGATGCTTTGGTTCATGATCCTCTGTCCCTCAAGCTGTTAACAGATGTCATAGGAAAGGATAAAGTCATTTTGGGAAC
CGATTACCCCTTTCCACTAGGTGAGCTGGAACCTGGGAAACTAATAGAGTCCATGGAAGAATTTGATGAAGAAACAAAGAATAAACTCAA
AGCCGGCAATGCCCTGGCATTTTTGGGTCTTGAGAGAAAACAATTTGAATGACTGAATTTACTACAAAGGCAAACTTTCAAAAGGATATC
TCATTTTTGTTTCTAAATATGTATCAACAGGTATCAACAAAATCCTATTTTGAACTATTTTACTCAGAAATGAATGTCCCAAATATCCTA

>71351_71351_9_RAB3GAP1-ACMSD_RAB3GAP1_chr2_135893502_ENST00000539493_ACMSD_chr2_135616831_ENST00000356140_length(amino acids)=899AA_BP=596
MFSLISGIFTSGTWEEKSDEISFADFKFSVTHHYLVQESTDKEGKDELLEDVVPQSMQDLLGMNNDFPPRAHCLVRWYGLREFVVIAPAA
HSDAVLSESKCNLLLSSVSIALGNTGCQVPLFVQIHHKWRRMYVGECQGPGVRTDFEMVHLRKVPNQYTHLSGLLDIFKSKIGCPLTPLP
PVSIAIRFTYVLQDWQQYFWPQQPPDIDALVGGEVGGLEFGKLPFGACEDPISELHLATTWPHLTEGIIVDNDVYSDLDPIQAPHWSVRV
RKAENPQCLLGDFVTEFFKICRRKESTDEILGRSAFEEEGKETADITHALSKLTEPASVPIHKLSVSNMVHTAKKKIRKHRGVEESPLNN
DVLNTILLFLFPDAVSEKPLDGTTSTDNNNPPSESEDYNLYNQFKSAPSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWEN
NFLIPGLASGPPDLRCCLLHQKLQMLNCCIERKKARDEGKKTSASDVTNIYPGDAGKAGDQLVPDNLKETDKEKGEVGKSWDSWSDSEEE
FFECLSDTEELKGNGQESGKKGGPKEMANLRPEGRLYQHGKLTLLHNGEPLYIPVTQGEAKLLKDGKVFRVVRENCWDPEVRIREMDQKG
VTVQALSTVPVMFSYWAKPEDTLNLCQLLNNDLASTVVSYPRRFVGLGTLPMQAPELAVKEMERCVKELGFPGVQIGTHVNEWDLNAQEL
FPVYAAAERLKCSLFVHPWDMQMDGRMAKYWLPWLVGMPAETTIAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTVGRISHGFSMRPDLC

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RAB3GAP1-ACMSD


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RAB3GAP1-ACMSD


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RAB3GAP1-ACMSD


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource