FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:RAB3GAP1-R3HDM1 (FusionGDB2 ID:71359)

Fusion Gene Summary for RAB3GAP1-R3HDM1

check button Fusion gene summary
Fusion gene informationFusion gene name: RAB3GAP1-R3HDM1
Fusion gene ID: 71359
HgeneTgene
Gene symbol

RAB3GAP1

R3HDM1

Gene ID

22930

23518

Gene nameRAB3 GTPase activating protein catalytic subunit 1R3H domain containing 1
SynonymsP130|RAB3GAP|RAB3GAP130|WARBM1R3HDM
Cytomap

2q21.3

2q21.3

Type of geneprotein-codingprotein-coding
Descriptionrab3 GTPase-activating protein catalytic subunitRAB3 GTPase activating protein subunit 1 (catalytic)RAB3 GTPase-activating protein 130 kDa subunitrab3-GAP p130R3H domain-containing protein 1R3H domain (binds single-stranded nucleic acids) containing
Modification date2020031320200320
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000264158, ENST00000425393, 
ENST00000442034, ENST00000539493, 
ENST00000487003, 
ENST00000443537, 
ENST00000264160, ENST00000329971, 
ENST00000409478, ENST00000409606, 
ENST00000410054, 
Fusion gene scores* DoF score13 X 11 X 9=128710 X 12 X 10=1200
# samples 1716
** MAII scorelog2(17/1287*10)=-2.920405402083
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(16/1200*10)=-2.90689059560852
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RAB3GAP1 [Title/Abstract] AND R3HDM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointR3HDM1(136362586)-RAB3GAP1(135815580), # samples:1
RAB3GAP1(135815656)-R3HDM1(136467003), # samples:1
RAB3GAP1(135843953)-R3HDM1(136467032), # samples:1
Anticipated loss of major functional domain due to fusion event.RAB3GAP1-R3HDM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
R3HDM1-RAB3GAP1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRAB3GAP1

GO:0043087

regulation of GTPase activity

10859313


check buttonFusion gene breakpoints across RAB3GAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across R3HDM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-76-4932-01ARAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
ChimerDB4LUSCTCGA-33-AASLRAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+


Top

Fusion Gene ORF analysis for RAB3GAP1-R3HDM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000264158ENST00000443537RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
5CDS-intronENST00000425393ENST00000443537RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
5CDS-intronENST00000442034ENST00000443537RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
5UTR-3CDSENST00000539493ENST00000264160RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
5UTR-3CDSENST00000539493ENST00000329971RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
5UTR-3CDSENST00000539493ENST00000409478RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
5UTR-3CDSENST00000539493ENST00000409606RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
5UTR-3CDSENST00000539493ENST00000410054RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
5UTR-intronENST00000539493ENST00000443537RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
Frame-shiftENST00000264158ENST00000264160RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
Frame-shiftENST00000264158ENST00000329971RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
Frame-shiftENST00000264158ENST00000409478RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
Frame-shiftENST00000264158ENST00000409606RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
Frame-shiftENST00000264158ENST00000410054RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
Frame-shiftENST00000442034ENST00000264160RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
Frame-shiftENST00000442034ENST00000329971RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
Frame-shiftENST00000442034ENST00000409478RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
Frame-shiftENST00000442034ENST00000409606RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
Frame-shiftENST00000442034ENST00000410054RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
In-frameENST00000425393ENST00000264160RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
In-frameENST00000425393ENST00000329971RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
In-frameENST00000425393ENST00000409478RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
In-frameENST00000425393ENST00000409606RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
In-frameENST00000425393ENST00000410054RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
intron-3CDSENST00000264158ENST00000264160RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000264158ENST00000329971RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000264158ENST00000409478RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000264158ENST00000409606RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000264158ENST00000410054RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000425393ENST00000264160RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000425393ENST00000329971RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000425393ENST00000409478RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000425393ENST00000409606RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000425393ENST00000410054RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000442034ENST00000264160RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000442034ENST00000329971RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000442034ENST00000409478RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000442034ENST00000409606RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000442034ENST00000410054RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000487003ENST00000264160RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
intron-3CDSENST00000487003ENST00000264160RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000487003ENST00000329971RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
intron-3CDSENST00000487003ENST00000329971RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000487003ENST00000409478RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
intron-3CDSENST00000487003ENST00000409478RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000487003ENST00000409606RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
intron-3CDSENST00000487003ENST00000409606RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000487003ENST00000410054RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
intron-3CDSENST00000487003ENST00000410054RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000539493ENST00000264160RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000539493ENST00000329971RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000539493ENST00000409478RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000539493ENST00000409606RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-3CDSENST00000539493ENST00000410054RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-intronENST00000264158ENST00000443537RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-intronENST00000425393ENST00000443537RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-intronENST00000442034ENST00000443537RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-intronENST00000487003ENST00000443537RAB3GAP1chr2

135815656

+R3HDM1chr2

136467003

+
intron-intronENST00000487003ENST00000443537RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+
intron-intronENST00000539493ENST00000443537RAB3GAP1chr2

135843953

+R3HDM1chr2

136467032

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000425393RAB3GAP1chr2135815656+ENST00000409478R3HDM1chr2136467003+298310639382008356
ENST00000425393RAB3GAP1chr2135815656+ENST00000329971R3HDM1chr2136467003+298310639382008356
ENST00000425393RAB3GAP1chr2135815656+ENST00000264160R3HDM1chr2136467003+298710639382008356
ENST00000425393RAB3GAP1chr2135815656+ENST00000410054R3HDM1chr2136467003+298510639382008356
ENST00000425393RAB3GAP1chr2135815656+ENST00000409606R3HDM1chr2136467003+206010639382008356

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000425393ENST00000409478RAB3GAP1chr2135815656+R3HDM1chr2136467003+0.0037530770.9962469
ENST00000425393ENST00000329971RAB3GAP1chr2135815656+R3HDM1chr2136467003+0.0037530770.9962469
ENST00000425393ENST00000264160RAB3GAP1chr2135815656+R3HDM1chr2136467003+0.0036926270.9963074
ENST00000425393ENST00000410054RAB3GAP1chr2135815656+R3HDM1chr2136467003+0.0037179690.99628204
ENST00000425393ENST00000409606RAB3GAP1chr2135815656+R3HDM1chr2136467003+0.0039375150.99606246

Top

Fusion Genomic Features for RAB3GAP1-R3HDM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RAB3GAP1chr2135815656+R3HDM1chr2136467002+2.05E-060.999998
RAB3GAP1chr2135815656+R3HDM1chr2136467002+2.05E-060.999998

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for RAB3GAP1-R3HDM1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:136362586/chr2:135815580)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneR3HDM1chr2:135815656chr2:136467003ENST000002641601926822_8267841100.0Compositional biasNote=Poly-Pro
TgeneR3HDM1chr2:135815656chr2:136467003ENST000003299711623822_826655971.0Compositional biasNote=Poly-Pro

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneR3HDM1chr2:135815656chr2:136467003ENST000002641601926589_6087841100.0Compositional biasNote=Poly-Pro
TgeneR3HDM1chr2:135815656chr2:136467003ENST00000264160192689_947841100.0Compositional biasNote=Poly-Pro
TgeneR3HDM1chr2:135815656chr2:136467003ENST000003299711623589_608655971.0Compositional biasNote=Poly-Pro
TgeneR3HDM1chr2:135815656chr2:136467003ENST00000329971162389_94655971.0Compositional biasNote=Poly-Pro
TgeneR3HDM1chr2:135815656chr2:136467003ENST000002641601926168_2317841100.0DomainR3H
TgeneR3HDM1chr2:135815656chr2:136467003ENST000002641601926232_3027841100.0DomainSUZ
TgeneR3HDM1chr2:135815656chr2:136467003ENST000003299711623168_231655971.0DomainR3H
TgeneR3HDM1chr2:135815656chr2:136467003ENST000003299711623232_302655971.0DomainSUZ


Top

Fusion Gene Sequence for RAB3GAP1-R3HDM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>71359_71359_1_RAB3GAP1-R3HDM1_RAB3GAP1_chr2_135815656_ENST00000425393_R3HDM1_chr2_136467003_ENST00000264160_length(transcript)=2987nt_BP=1063nt
CTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGACTTCACCACTGCCTCGGAATGGGAAAGGTCAGAT
CTATTTGCTGGTGTCTCTAAATGACTATTTACTTTGAAACCTCTATTTTCCAGCCCTTTGCTGCATTTGGCACATTTGAATTAAATGTTT
TTTAAAGTTACGTATAATCTATAAACATCAAATAGCATTTGGAAGAATTTGGATTTAAATCTGTGGCAAATGATATATGTAAGACATTTG
TGAAATGTTTAATAAAGTTATATATATGTGTGTGTGTATATATATATATATAAAATGTCATTCTTTGTGAGTGATTCTTTGTGAGTGAAG
TTTGCTTCTCTTTTGCCTTCTCCCTTGGAATGTTAAAACATGTTTTTAAAAGTTTTTTATTTGGTCAGAGAAACATTGCAGTGACCATCT
TCTTTGGTAGCATATTTTGCTTACTAATGAGGAAAATTCTAGTACTTACCATTGACTTACTGTAGTTAACAACTATTTCACTCAGTTTTT
GTATTTTATAATATCACTAATAACATCCCCCTTCCCTTTTAAGCTTTTTAACTTATGGATGTTTTAAGGATTTTATTTAAGAATGAAAAA
ATTACTCTTTGAAATTGAGGTAGAAATCAAATTCTAATCTAAAGTATTGGTAGTTTTATTCATAAACCACACCCCAAATGTTTACTGAAG
AATGTACTCTGAGAACAAACCTGGATTCACTGTGAAGGGATCTAACAATTTGATTTTAAGTTTATGTAGATGCTTAGTTTGTTAGATAAA
TTCTTTTGAAATAAAATTTATGGTTGGTTTTATTACAACTCAATATTACTAACTCAGTGATAACTTATTAACTCAGTAATTATTAATTCA
ATAGTAATTTAATTATAATTTACCCTGTGTTAGGAACTTTGAGTTCTCAATATTTGCTAGGGGTTTTCAGCTTTGTGATGGTGATACTAT
CAAAAAAGAGACTGTCAAAATGCATTAGGAAGCCAGGCAACATGGTGAGACCCTGTCTCTTAAGGAAAAAAAACTCTTCAGTAGGTTACC
TGCAACATCCAGGATCAGAACAAGTACAATTTCCTCGAACCACTTCACCATGCAGTTCCCAGCAGCTTCAAGGCCACCAATGTACAGCTG
GACCACCACCGCCACCTGGTGGGGGGATGGTGATGATGCAGCTCAGTGTACCAAACAATCCACAATCTTGTGCCCACTCACCCCCGCAGT
GGAAACAAAACAAATATTACTGTGATCACCAGAGAGGACAGAAGTGTGTAGAATTTAGCAGTGTAGACAATATTGTCCAGCACAGCCCTC
AACTCAGTAGCCCCATTATTTCACCAGCTCAGTCGCCAGCACCAGCTCAGCTGTCCACCCTGAAAACTGTACGTCCCTCTGGACCACCAC
TTTCCATCATGCCCCAATTTTCTAGACCTTTTGTCCCCGGGCAAGGAGATTCCAGGTATCCATTACTTGGCCAGCCACTGCAGTACAATC
CTCCTGCTGTTCTGCACGGACACATTCCAAACCAACAGGGTCAGCCTGGCAGCAGGCATGGAAACCGAGGAAGGAGACAAGCTAAAAAAG
CTGCATCCACAGACCTTGGAGCAGGAGAAACAGTTGTTGGGAAGGTCTTGGAAATTACTGAACTACCAGATGGAATAACTCGCATGGAAG
CTGAAAAGCTTTTTGGGGAACTCTTTAAAATTGGCGCCAAGATCCGGTGGCTCCGGGACCCCCAGTCCCAACCACGTCGTCACCCCCTCT
GCTGTGGCAGTGGGGACAACACTGCCAACCCTGAACGCTCTAAACCCAGTGACTTGGCCTCCACCTACACCGTCTTAGCCACATTCCCCT
CCATTTCAGCTGCACAGAATGCACTGAAGAAACAAATTAACTCAGTTAACAAGTTTAAGCTGAGAACAAGCAAGAAGCACTATGACTTTC
ACATTTTGGAAAGGGCAAGTTCTCAGTAACAGCCACCTTTGGACCCTTCGCCTTTATGGTTCCCCTGCCCTCTCCCATCTTTGATTGGCT
TGGTATTTGGAGCTTCTGTTAACATTATAGAGACTCCTAGGATGTGTGTTCATGGCATTATAGCTTTTGAAGAAAGGCCAGTGATCCAGC
AAAGGGGGAAAAATATGCATTTCACCCCACATGACTAGGAATCCACATCAGAATGATACAGAGTTAGCAGGTTTTTCTAAGGAAATGCCA
TTCAAATGCCTCCTAACTTTTATAGTTATTTTGTTTTATATTTCTAAATTCTTGTATCAGATCCAAAGCTCTATTGTACAGCAAATTATT
CTTCAAAATGATTATAACCAGTTGCACCCTGTATTTCTTTTTGCAGCCAGCACAATGTGACCCAACTTAAAATTTGGGGGAAAAAGAATG
CAGGAGTGAAATAACCAAGTCAAAACCATGTACTATCTCCTTGGGGGTTAGGGATGCTAAGAAGAGCCCACAAATAGAGGATTACTCTTC
CCCTGAATCTCTAAACTCAGAAACAATTACCAAAAAATACATAACTCTTCCTTGTAGGGCCCTTTCCTTATTCATTTAGGTAGTGTGAAC
ATTAAGTATAAAATAAATTATGTTCTTAATGCCTCTTAAACCACTTACATTCAAAGGGGAACAGAAATCATTCTAAGCAGGAAAATACTT
CCACTTTTTTTTTTTCAAGTATCTCTCTAATAACTAAATGCCACTTATTTGCATTCTCCTTGTGGATTTTTTGTCACCTAAGGAAATGCA
TTTGATGAGTGCTGGAAACTTCTTAAGTGCTTTACAGTTTGTTTTCATTGTTTGCAGCGGATCACTGGACATCAAAGATTCATTGCACTT
ATGAACAAGGAACCTTCTTTTCAATTTCTGTGTAATTTGCAAGGCTGTACAATGTGTGCTGATGCAAGCCTTTTTCAGTTCAAGAGAATA

>71359_71359_1_RAB3GAP1-R3HDM1_RAB3GAP1_chr2_135815656_ENST00000425393_R3HDM1_chr2_136467003_ENST00000264160_length(amino acids)=356AA_BP=42
MSSQYLLGVFSFVMVILSKKRLSKCIRKPGNMVRPCLLRKKNSSVGYLQHPGSEQVQFPRTTSPCSSQQLQGHQCTAGPPPPPGGGMVMM
QLSVPNNPQSCAHSPPQWKQNKYYCDHQRGQKCVEFSSVDNIVQHSPQLSSPIISPAQSPAPAQLSTLKTVRPSGPPLSIMPQFSRPFVP
GQGDSRYPLLGQPLQYNPPAVLHGHIPNQQGQPGSRHGNRGRRQAKKAASTDLGAGETVVGKVLEITELPDGITRMEAEKLFGELFKIGA

--------------------------------------------------------------
>71359_71359_2_RAB3GAP1-R3HDM1_RAB3GAP1_chr2_135815656_ENST00000425393_R3HDM1_chr2_136467003_ENST00000329971_length(transcript)=2983nt_BP=1063nt
CTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGACTTCACCACTGCCTCGGAATGGGAAAGGTCAGAT
CTATTTGCTGGTGTCTCTAAATGACTATTTACTTTGAAACCTCTATTTTCCAGCCCTTTGCTGCATTTGGCACATTTGAATTAAATGTTT
TTTAAAGTTACGTATAATCTATAAACATCAAATAGCATTTGGAAGAATTTGGATTTAAATCTGTGGCAAATGATATATGTAAGACATTTG
TGAAATGTTTAATAAAGTTATATATATGTGTGTGTGTATATATATATATATAAAATGTCATTCTTTGTGAGTGATTCTTTGTGAGTGAAG
TTTGCTTCTCTTTTGCCTTCTCCCTTGGAATGTTAAAACATGTTTTTAAAAGTTTTTTATTTGGTCAGAGAAACATTGCAGTGACCATCT
TCTTTGGTAGCATATTTTGCTTACTAATGAGGAAAATTCTAGTACTTACCATTGACTTACTGTAGTTAACAACTATTTCACTCAGTTTTT
GTATTTTATAATATCACTAATAACATCCCCCTTCCCTTTTAAGCTTTTTAACTTATGGATGTTTTAAGGATTTTATTTAAGAATGAAAAA
ATTACTCTTTGAAATTGAGGTAGAAATCAAATTCTAATCTAAAGTATTGGTAGTTTTATTCATAAACCACACCCCAAATGTTTACTGAAG
AATGTACTCTGAGAACAAACCTGGATTCACTGTGAAGGGATCTAACAATTTGATTTTAAGTTTATGTAGATGCTTAGTTTGTTAGATAAA
TTCTTTTGAAATAAAATTTATGGTTGGTTTTATTACAACTCAATATTACTAACTCAGTGATAACTTATTAACTCAGTAATTATTAATTCA
ATAGTAATTTAATTATAATTTACCCTGTGTTAGGAACTTTGAGTTCTCAATATTTGCTAGGGGTTTTCAGCTTTGTGATGGTGATACTAT
CAAAAAAGAGACTGTCAAAATGCATTAGGAAGCCAGGCAACATGGTGAGACCCTGTCTCTTAAGGAAAAAAAACTCTTCAGTAGGTTACC
TGCAACATCCAGGATCAGAACAAGTACAATTTCCTCGAACCACTTCACCATGCAGTTCCCAGCAGCTTCAAGGCCACCAATGTACAGCTG
GACCACCACCGCCACCTGGTGGGGGGATGGTGATGATGCAGCTCAGTGTACCAAACAATCCACAATCTTGTGCCCACTCACCCCCGCAGT
GGAAACAAAACAAATATTACTGTGATCACCAGAGAGGACAGAAGTGTGTAGAATTTAGCAGTGTAGACAATATTGTCCAGCACAGCCCTC
AACTCAGTAGCCCCATTATTTCACCAGCTCAGTCGCCAGCACCAGCTCAGCTGTCCACCCTGAAAACTGTACGTCCCTCTGGACCACCAC
TTTCCATCATGCCCCAATTTTCTAGACCTTTTGTCCCCGGGCAAGGAGATTCCAGGTATCCATTACTTGGCCAGCCACTGCAGTACAATC
CTCCTGCTGTTCTGCACGGACACATTCCAAACCAACAGGGTCAGCCTGGCAGCAGGCATGGAAACCGAGGAAGGAGACAAGCTAAAAAAG
CTGCATCCACAGACCTTGGAGCAGGAGAAACAGTTGTTGGGAAGGTCTTGGAAATTACTGAACTACCAGATGGAATAACTCGCATGGAAG
CTGAAAAGCTTTTTGGGGAACTCTTTAAAATTGGCGCCAAGATCCGGTGGCTCCGGGACCCCCAGTCCCAACCACGTCGTCACCCCCTCT
GCTGTGGCAGTGGGGACAACACTGCCAACCCTGAACGCTCTAAACCCAGTGACTTGGCCTCCACCTACACCGTCTTAGCCACATTCCCCT
CCATTTCAGCTGCACAGAATGCACTGAAGAAACAAATTAACTCAGTTAACAAGTTTAAGCTGAGAACAAGCAAGAAGCACTATGACTTTC
ACATTTTGGAAAGGGCAAGTTCTCAGTAACAGCCACCTTTGGACCCTTCGCCTTTATGGTTCCCCTGCCCTCTCCCATCTTTGATTGGCT
TGGTATTTGGAGCTTCTGTTAACATTATAGAGACTCCTAGGATGTGTGTTCATGGCATTATAGCTTTTGAAGAAAGGCCAGTGATCCAGC
AAAGGGGGAAAAATATGCATTTCACCCCACATGACTAGGAATCCACATCAGAATGATACAGAGTTAGCAGGTTTTTCTAAGGAAATGCCA
TTCAAATGCCTCCTAACTTTTATAGTTATTTTGTTTTATATTTCTAAATTCTTGTATCAGATCCAAAGCTCTATTGTACAGCAAATTATT
CTTCAAAATGATTATAACCAGTTGCACCCTGTATTTCTTTTTGCAGCCAGCACAATGTGACCCAACTTAAAATTTGGGGGAAAAAGAATG
CAGGAGTGAAATAACCAAGTCAAAACCATGTACTATCTCCTTGGGGGTTAGGGATGCTAAGAAGAGCCCACAAATAGAGGATTACTCTTC
CCCTGAATCTCTAAACTCAGAAACAATTACCAAAAAATACATAACTCTTCCTTGTAGGGCCCTTTCCTTATTCATTTAGGTAGTGTGAAC
ATTAAGTATAAAATAAATTATGTTCTTAATGCCTCTTAAACCACTTACATTCAAAGGGGAACAGAAATCATTCTAAGCAGGAAAATACTT
CCACTTTTTTTTTTTCAAGTATCTCTCTAATAACTAAATGCCACTTATTTGCATTCTCCTTGTGGATTTTTTGTCACCTAAGGAAATGCA
TTTGATGAGTGCTGGAAACTTCTTAAGTGCTTTACAGTTTGTTTTCATTGTTTGCAGCGGATCACTGGACATCAAAGATTCATTGCACTT
ATGAACAAGGAACCTTCTTTTCAATTTCTGTGTAATTTGCAAGGCTGTACAATGTGTGCTGATGCAAGCCTTTTTCAGTTCAAGAGAATA

>71359_71359_2_RAB3GAP1-R3HDM1_RAB3GAP1_chr2_135815656_ENST00000425393_R3HDM1_chr2_136467003_ENST00000329971_length(amino acids)=356AA_BP=42
MSSQYLLGVFSFVMVILSKKRLSKCIRKPGNMVRPCLLRKKNSSVGYLQHPGSEQVQFPRTTSPCSSQQLQGHQCTAGPPPPPGGGMVMM
QLSVPNNPQSCAHSPPQWKQNKYYCDHQRGQKCVEFSSVDNIVQHSPQLSSPIISPAQSPAPAQLSTLKTVRPSGPPLSIMPQFSRPFVP
GQGDSRYPLLGQPLQYNPPAVLHGHIPNQQGQPGSRHGNRGRRQAKKAASTDLGAGETVVGKVLEITELPDGITRMEAEKLFGELFKIGA

--------------------------------------------------------------
>71359_71359_3_RAB3GAP1-R3HDM1_RAB3GAP1_chr2_135815656_ENST00000425393_R3HDM1_chr2_136467003_ENST00000409478_length(transcript)=2983nt_BP=1063nt
CTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGACTTCACCACTGCCTCGGAATGGGAAAGGTCAGAT
CTATTTGCTGGTGTCTCTAAATGACTATTTACTTTGAAACCTCTATTTTCCAGCCCTTTGCTGCATTTGGCACATTTGAATTAAATGTTT
TTTAAAGTTACGTATAATCTATAAACATCAAATAGCATTTGGAAGAATTTGGATTTAAATCTGTGGCAAATGATATATGTAAGACATTTG
TGAAATGTTTAATAAAGTTATATATATGTGTGTGTGTATATATATATATATAAAATGTCATTCTTTGTGAGTGATTCTTTGTGAGTGAAG
TTTGCTTCTCTTTTGCCTTCTCCCTTGGAATGTTAAAACATGTTTTTAAAAGTTTTTTATTTGGTCAGAGAAACATTGCAGTGACCATCT
TCTTTGGTAGCATATTTTGCTTACTAATGAGGAAAATTCTAGTACTTACCATTGACTTACTGTAGTTAACAACTATTTCACTCAGTTTTT
GTATTTTATAATATCACTAATAACATCCCCCTTCCCTTTTAAGCTTTTTAACTTATGGATGTTTTAAGGATTTTATTTAAGAATGAAAAA
ATTACTCTTTGAAATTGAGGTAGAAATCAAATTCTAATCTAAAGTATTGGTAGTTTTATTCATAAACCACACCCCAAATGTTTACTGAAG
AATGTACTCTGAGAACAAACCTGGATTCACTGTGAAGGGATCTAACAATTTGATTTTAAGTTTATGTAGATGCTTAGTTTGTTAGATAAA
TTCTTTTGAAATAAAATTTATGGTTGGTTTTATTACAACTCAATATTACTAACTCAGTGATAACTTATTAACTCAGTAATTATTAATTCA
ATAGTAATTTAATTATAATTTACCCTGTGTTAGGAACTTTGAGTTCTCAATATTTGCTAGGGGTTTTCAGCTTTGTGATGGTGATACTAT
CAAAAAAGAGACTGTCAAAATGCATTAGGAAGCCAGGCAACATGGTGAGACCCTGTCTCTTAAGGAAAAAAAACTCTTCAGTAGGTTACC
TGCAACATCCAGGATCAGAACAAGTACAATTTCCTCGAACCACTTCACCATGCAGTTCCCAGCAGCTTCAAGGCCACCAATGTACAGCTG
GACCACCACCGCCACCTGGTGGGGGGATGGTGATGATGCAGCTCAGTGTACCAAACAATCCACAATCTTGTGCCCACTCACCCCCGCAGT
GGAAACAAAACAAATATTACTGTGATCACCAGAGAGGACAGAAGTGTGTAGAATTTAGCAGTGTAGACAATATTGTCCAGCACAGCCCTC
AACTCAGTAGCCCCATTATTTCACCAGCTCAGTCGCCAGCACCAGCTCAGCTGTCCACCCTGAAAACTGTACGTCCCTCTGGACCACCAC
TTTCCATCATGCCCCAATTTTCTAGACCTTTTGTCCCCGGGCAAGGAGATTCCAGGTATCCATTACTTGGCCAGCCACTGCAGTACAATC
CTCCTGCTGTTCTGCACGGACACATTCCAAACCAACAGGGTCAGCCTGGCAGCAGGCATGGAAACCGAGGAAGGAGACAAGCTAAAAAAG
CTGCATCCACAGACCTTGGAGCAGGAGAAACAGTTGTTGGGAAGGTCTTGGAAATTACTGAACTACCAGATGGAATAACTCGCATGGAAG
CTGAAAAGCTTTTTGGGGAACTCTTTAAAATTGGCGCCAAGATCCGGTGGCTCCGGGACCCCCAGTCCCAACCACGTCGTCACCCCCTCT
GCTGTGGCAGTGGGGACAACACTGCCAACCCTGAACGCTCTAAACCCAGTGACTTGGCCTCCACCTACACCGTCTTAGCCACATTCCCCT
CCATTTCAGCTGCACAGAATGCACTGAAGAAACAAATTAACTCAGTTAACAAGTTTAAGCTGAGAACAAGCAAGAAGCACTATGACTTTC
ACATTTTGGAAAGGGCAAGTTCTCAGTAACAGCCACCTTTGGACCCTTCGCCTTTATGGTTCCCCTGCCCTCTCCCATCTTTGATTGGCT
TGGTATTTGGAGCTTCTGTTAACATTATAGAGACTCCTAGGATGTGTGTTCATGGCATTATAGCTTTTGAAGAAAGGCCAGTGATCCAGC
AAAGGGGGAAAAATATGCATTTCACCCCACATGACTAGGAATCCACATCAGAATGATACAGAGTTAGCAGGTTTTTCTAAGGAAATGCCA
TTCAAATGCCTCCTAACTTTTATAGTTATTTTGTTTTATATTTCTAAATTCTTGTATCAGATCCAAAGCTCTATTGTACAGCAAATTATT
CTTCAAAATGATTATAACCAGTTGCACCCTGTATTTCTTTTTGCAGCCAGCACAATGTGACCCAACTTAAAATTTGGGGGAAAAAGAATG
CAGGAGTGAAATAACCAAGTCAAAACCATGTACTATCTCCTTGGGGGTTAGGGATGCTAAGAAGAGCCCACAAATAGAGGATTACTCTTC
CCCTGAATCTCTAAACTCAGAAACAATTACCAAAAAATACATAACTCTTCCTTGTAGGGCCCTTTCCTTATTCATTTAGGTAGTGTGAAC
ATTAAGTATAAAATAAATTATGTTCTTAATGCCTCTTAAACCACTTACATTCAAAGGGGAACAGAAATCATTCTAAGCAGGAAAATACTT
CCACTTTTTTTTTTTCAAGTATCTCTCTAATAACTAAATGCCACTTATTTGCATTCTCCTTGTGGATTTTTTGTCACCTAAGGAAATGCA
TTTGATGAGTGCTGGAAACTTCTTAAGTGCTTTACAGTTTGTTTTCATTGTTTGCAGCGGATCACTGGACATCAAAGATTCATTGCACTT
ATGAACAAGGAACCTTCTTTTCAATTTCTGTGTAATTTGCAAGGCTGTACAATGTGTGCTGATGCAAGCCTTTTTCAGTTCAAGAGAATA

>71359_71359_3_RAB3GAP1-R3HDM1_RAB3GAP1_chr2_135815656_ENST00000425393_R3HDM1_chr2_136467003_ENST00000409478_length(amino acids)=356AA_BP=42
MSSQYLLGVFSFVMVILSKKRLSKCIRKPGNMVRPCLLRKKNSSVGYLQHPGSEQVQFPRTTSPCSSQQLQGHQCTAGPPPPPGGGMVMM
QLSVPNNPQSCAHSPPQWKQNKYYCDHQRGQKCVEFSSVDNIVQHSPQLSSPIISPAQSPAPAQLSTLKTVRPSGPPLSIMPQFSRPFVP
GQGDSRYPLLGQPLQYNPPAVLHGHIPNQQGQPGSRHGNRGRRQAKKAASTDLGAGETVVGKVLEITELPDGITRMEAEKLFGELFKIGA

--------------------------------------------------------------
>71359_71359_4_RAB3GAP1-R3HDM1_RAB3GAP1_chr2_135815656_ENST00000425393_R3HDM1_chr2_136467003_ENST00000409606_length(transcript)=2060nt_BP=1063nt
CTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGACTTCACCACTGCCTCGGAATGGGAAAGGTCAGAT
CTATTTGCTGGTGTCTCTAAATGACTATTTACTTTGAAACCTCTATTTTCCAGCCCTTTGCTGCATTTGGCACATTTGAATTAAATGTTT
TTTAAAGTTACGTATAATCTATAAACATCAAATAGCATTTGGAAGAATTTGGATTTAAATCTGTGGCAAATGATATATGTAAGACATTTG
TGAAATGTTTAATAAAGTTATATATATGTGTGTGTGTATATATATATATATAAAATGTCATTCTTTGTGAGTGATTCTTTGTGAGTGAAG
TTTGCTTCTCTTTTGCCTTCTCCCTTGGAATGTTAAAACATGTTTTTAAAAGTTTTTTATTTGGTCAGAGAAACATTGCAGTGACCATCT
TCTTTGGTAGCATATTTTGCTTACTAATGAGGAAAATTCTAGTACTTACCATTGACTTACTGTAGTTAACAACTATTTCACTCAGTTTTT
GTATTTTATAATATCACTAATAACATCCCCCTTCCCTTTTAAGCTTTTTAACTTATGGATGTTTTAAGGATTTTATTTAAGAATGAAAAA
ATTACTCTTTGAAATTGAGGTAGAAATCAAATTCTAATCTAAAGTATTGGTAGTTTTATTCATAAACCACACCCCAAATGTTTACTGAAG
AATGTACTCTGAGAACAAACCTGGATTCACTGTGAAGGGATCTAACAATTTGATTTTAAGTTTATGTAGATGCTTAGTTTGTTAGATAAA
TTCTTTTGAAATAAAATTTATGGTTGGTTTTATTACAACTCAATATTACTAACTCAGTGATAACTTATTAACTCAGTAATTATTAATTCA
ATAGTAATTTAATTATAATTTACCCTGTGTTAGGAACTTTGAGTTCTCAATATTTGCTAGGGGTTTTCAGCTTTGTGATGGTGATACTAT
CAAAAAAGAGACTGTCAAAATGCATTAGGAAGCCAGGCAACATGGTGAGACCCTGTCTCTTAAGGAAAAAAAACTCTTCAGTAGGTTACC
TGCAACATCCAGGATCAGAACAAGTACAATTTCCTCGAACCACTTCACCATGCAGTTCCCAGCAGCTTCAAGGCCACCAATGTACAGCTG
GACCACCACCGCCACCTGGTGGGGGGATGGTGATGATGCAGCTCAGTGTACCAAACAATCCACAATCTTGTGCCCACTCACCCCCGCAGT
GGAAACAAAACAAATATTACTGTGATCACCAGAGAGGACAGAAGTGTGTAGAATTTAGCAGTGTAGACAATATTGTCCAGCACAGCCCTC
AACTCAGTAGCCCCATTATTTCACCAGCTCAGTCGCCAGCACCAGCTCAGCTGTCCACCCTGAAAACTGTACGTCCCTCTGGACCACCAC
TTTCCATCATGCCCCAATTTTCTAGACCTTTTGTCCCCGGGCAAGGAGATTCCAGGTATCCATTACTTGGCCAGCCACTGCAGTACAATC
CTCCTGCTGTTCTGCACGGACACATTCCAAACCAACAGGGTCAGCCTGGCAGCAGGCATGGAAACCGAGGAAGGAGACAAGCTAAAAAAG
CTGCATCCACAGACCTTGGAGCAGGAGAAACAGTTGTTGGGAAGGTCTTGGAAATTACTGAACTACCAGATGGAATAACTCGCATGGAAG
CTGAAAAGCTTTTTGGGGAACTCTTTAAAATTGGCGCCAAGATCCGGTGGCTCCGGGACCCCCAGTCCCAACCACGTCGTCACCCCCTCT
GCTGTGGCAGTGGGGACAACACTGCCAACCCTGAACGCTCTAAACCCAGTGACTTGGCCTCCACCTACACCGTCTTAGCCACATTCCCCT
CCATTTCAGCTGCACAGAATGCACTGAAGAAACAAATTAACTCAGTTAACAAGTTTAAGCTGAGAACAAGCAAGAAGCACTATGACTTTC

>71359_71359_4_RAB3GAP1-R3HDM1_RAB3GAP1_chr2_135815656_ENST00000425393_R3HDM1_chr2_136467003_ENST00000409606_length(amino acids)=356AA_BP=42
MSSQYLLGVFSFVMVILSKKRLSKCIRKPGNMVRPCLLRKKNSSVGYLQHPGSEQVQFPRTTSPCSSQQLQGHQCTAGPPPPPGGGMVMM
QLSVPNNPQSCAHSPPQWKQNKYYCDHQRGQKCVEFSSVDNIVQHSPQLSSPIISPAQSPAPAQLSTLKTVRPSGPPLSIMPQFSRPFVP
GQGDSRYPLLGQPLQYNPPAVLHGHIPNQQGQPGSRHGNRGRRQAKKAASTDLGAGETVVGKVLEITELPDGITRMEAEKLFGELFKIGA

--------------------------------------------------------------
>71359_71359_5_RAB3GAP1-R3HDM1_RAB3GAP1_chr2_135815656_ENST00000425393_R3HDM1_chr2_136467003_ENST00000410054_length(transcript)=2985nt_BP=1063nt
CTCCTCAAGATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGACTTCACCACTGCCTCGGAATGGGAAAGGTCAGAT
CTATTTGCTGGTGTCTCTAAATGACTATTTACTTTGAAACCTCTATTTTCCAGCCCTTTGCTGCATTTGGCACATTTGAATTAAATGTTT
TTTAAAGTTACGTATAATCTATAAACATCAAATAGCATTTGGAAGAATTTGGATTTAAATCTGTGGCAAATGATATATGTAAGACATTTG
TGAAATGTTTAATAAAGTTATATATATGTGTGTGTGTATATATATATATATAAAATGTCATTCTTTGTGAGTGATTCTTTGTGAGTGAAG
TTTGCTTCTCTTTTGCCTTCTCCCTTGGAATGTTAAAACATGTTTTTAAAAGTTTTTTATTTGGTCAGAGAAACATTGCAGTGACCATCT
TCTTTGGTAGCATATTTTGCTTACTAATGAGGAAAATTCTAGTACTTACCATTGACTTACTGTAGTTAACAACTATTTCACTCAGTTTTT
GTATTTTATAATATCACTAATAACATCCCCCTTCCCTTTTAAGCTTTTTAACTTATGGATGTTTTAAGGATTTTATTTAAGAATGAAAAA
ATTACTCTTTGAAATTGAGGTAGAAATCAAATTCTAATCTAAAGTATTGGTAGTTTTATTCATAAACCACACCCCAAATGTTTACTGAAG
AATGTACTCTGAGAACAAACCTGGATTCACTGTGAAGGGATCTAACAATTTGATTTTAAGTTTATGTAGATGCTTAGTTTGTTAGATAAA
TTCTTTTGAAATAAAATTTATGGTTGGTTTTATTACAACTCAATATTACTAACTCAGTGATAACTTATTAACTCAGTAATTATTAATTCA
ATAGTAATTTAATTATAATTTACCCTGTGTTAGGAACTTTGAGTTCTCAATATTTGCTAGGGGTTTTCAGCTTTGTGATGGTGATACTAT
CAAAAAAGAGACTGTCAAAATGCATTAGGAAGCCAGGCAACATGGTGAGACCCTGTCTCTTAAGGAAAAAAAACTCTTCAGTAGGTTACC
TGCAACATCCAGGATCAGAACAAGTACAATTTCCTCGAACCACTTCACCATGCAGTTCCCAGCAGCTTCAAGGCCACCAATGTACAGCTG
GACCACCACCGCCACCTGGTGGGGGGATGGTGATGATGCAGCTCAGTGTACCAAACAATCCACAATCTTGTGCCCACTCACCCCCGCAGT
GGAAACAAAACAAATATTACTGTGATCACCAGAGAGGACAGAAGTGTGTAGAATTTAGCAGTGTAGACAATATTGTCCAGCACAGCCCTC
AACTCAGTAGCCCCATTATTTCACCAGCTCAGTCGCCAGCACCAGCTCAGCTGTCCACCCTGAAAACTGTACGTCCCTCTGGACCACCAC
TTTCCATCATGCCCCAATTTTCTAGACCTTTTGTCCCCGGGCAAGGAGATTCCAGGTATCCATTACTTGGCCAGCCACTGCAGTACAATC
CTCCTGCTGTTCTGCACGGACACATTCCAAACCAACAGGGTCAGCCTGGCAGCAGGCATGGAAACCGAGGAAGGAGACAAGCTAAAAAAG
CTGCATCCACAGACCTTGGAGCAGGAGAAACAGTTGTTGGGAAGGTCTTGGAAATTACTGAACTACCAGATGGAATAACTCGCATGGAAG
CTGAAAAGCTTTTTGGGGAACTCTTTAAAATTGGCGCCAAGATCCGGTGGCTCCGGGACCCCCAGTCCCAACCACGTCGTCACCCCCTCT
GCTGTGGCAGTGGGGACAACACTGCCAACCCTGAACGCTCTAAACCCAGTGACTTGGCCTCCACCTACACCGTCTTAGCCACATTCCCCT
CCATTTCAGCTGCACAGAATGCACTGAAGAAACAAATTAACTCAGTTAACAAGTTTAAGCTGAGAACAAGCAAGAAGCACTATGACTTTC
ACATTTTGGAAAGGGCAAGTTCTCAGTAACAGCCACCTTTGGACCCTTCGCCTTTATGGTTCCCCTGCCCTCTCCCATCTTTGATTGGCT
TGGTATTTGGAGCTTCTGTTAACATTATAGAGACTCCTAGGATGTGTGTTCATGGCATTATAGCTTTTGAAGAAAGGCCAGTGATCCAGC
AAAGGGGGAAAAATATGCATTTCACCCCACATGACTAGGAATCCACATCAGAATGATACAGAGTTAGCAGGTTTTTCTAAGGAAATGCCA
TTCAAATGCCTCCTAACTTTTATAGTTATTTTGTTTTATATTTCTAAATTCTTGTATCAGATCCAAAGCTCTATTGTACAGCAAATTATT
CTTCAAAATGATTATAACCAGTTGCACCCTGTATTTCTTTTTGCAGCCAGCACAATGTGACCCAACTTAAAATTTGGGGGAAAAAGAATG
CAGGAGTGAAATAACCAAGTCAAAACCATGTACTATCTCCTTGGGGGTTAGGGATGCTAAGAAGAGCCCACAAATAGAGGATTACTCTTC
CCCTGAATCTCTAAACTCAGAAACAATTACCAAAAAATACATAACTCTTCCTTGTAGGGCCCTTTCCTTATTCATTTAGGTAGTGTGAAC
ATTAAGTATAAAATAAATTATGTTCTTAATGCCTCTTAAACCACTTACATTCAAAGGGGAACAGAAATCATTCTAAGCAGGAAAATACTT
CCACTTTTTTTTTTTCAAGTATCTCTCTAATAACTAAATGCCACTTATTTGCATTCTCCTTGTGGATTTTTTGTCACCTAAGGAAATGCA
TTTGATGAGTGCTGGAAACTTCTTAAGTGCTTTACAGTTTGTTTTCATTGTTTGCAGCGGATCACTGGACATCAAAGATTCATTGCACTT
ATGAACAAGGAACCTTCTTTTCAATTTCTGTGTAATTTGCAAGGCTGTACAATGTGTGCTGATGCAAGCCTTTTTCAGTTCAAGAGAATA

>71359_71359_5_RAB3GAP1-R3HDM1_RAB3GAP1_chr2_135815656_ENST00000425393_R3HDM1_chr2_136467003_ENST00000410054_length(amino acids)=356AA_BP=42
MSSQYLLGVFSFVMVILSKKRLSKCIRKPGNMVRPCLLRKKNSSVGYLQHPGSEQVQFPRTTSPCSSQQLQGHQCTAGPPPPPGGGMVMM
QLSVPNNPQSCAHSPPQWKQNKYYCDHQRGQKCVEFSSVDNIVQHSPQLSSPIISPAQSPAPAQLSTLKTVRPSGPPLSIMPQFSRPFVP
GQGDSRYPLLGQPLQYNPPAVLHGHIPNQQGQPGSRHGNRGRRQAKKAASTDLGAGETVVGKVLEITELPDGITRMEAEKLFGELFKIGA

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for RAB3GAP1-R3HDM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for RAB3GAP1-R3HDM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for RAB3GAP1-R3HDM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource