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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RAB3IP-CHD1L (FusionGDB2 ID:71387)

Fusion Gene Summary for RAB3IP-CHD1L

check button Fusion gene summary
Fusion gene informationFusion gene name: RAB3IP-CHD1L
Fusion gene ID: 71387
HgeneTgene
Gene symbol

RAB3IP

CHD1L

Gene ID

117177

9557

Gene nameRAB3A interacting proteinchromodomain helicase DNA binding protein 1 like
SynonymsRABIN3|RABIN8ALC1|CHDL
Cytomap

12q15

1q21.1

Type of geneprotein-codingprotein-coding
Descriptionrab-3A-interacting proteinSSX2 interacting proteinrab3A-interacting proteinrabin-3chromodomain-helicase-DNA-binding protein 1-likeamplified in liver cancer 1amplified in liver cancer protein 1
Modification date2020032720200313
UniProtAcc.

Q86WJ1

Ensembl transtripts involved in fusion geneENST00000247833, ENST00000362025, 
ENST00000378815, ENST00000483530, 
ENST00000550536, ENST00000325555, 
ENST00000550847, ENST00000551641, 
ENST00000553099, 		ENST00000467213, 
ENST00000361293, ENST00000369258, 
ENST00000369259, ENST00000431239, 
Fusion gene scores* DoF score21 X 9 X 12=226810 X 11 X 5=550
# samples 2714
** MAII scorelog2(27/2268*10)=-3.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/550*10)=-1.97400479146706
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RAB3IP [Title/Abstract] AND CHD1L [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRAB3IP(70150443)-CHD1L(146736080), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRAB3IP

GO:0006612

protein targeting to membrane

23382462

TgeneCHD1L

GO:0006338

chromatin remodeling

19661379

TgeneCHD1L

GO:0006974

cellular response to DNA damage stimulus

19661379


check buttonFusion gene breakpoints across RAB3IP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CHD1L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer61NRAB3IPchr12

70150443

+CHD1Lchr1

146736080

+


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Fusion Gene ORF analysis for RAB3IP-CHD1L

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000247833ENST00000467213RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-3UTRENST00000362025ENST00000467213RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-3UTRENST00000378815ENST00000467213RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-3UTRENST00000483530ENST00000467213RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-3UTRENST00000550536ENST00000467213RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000247833ENST00000361293RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000247833ENST00000369258RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000247833ENST00000369259RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000362025ENST00000361293RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000362025ENST00000369258RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000362025ENST00000369259RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000378815ENST00000361293RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000378815ENST00000369258RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000378815ENST00000369259RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000483530ENST00000361293RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000483530ENST00000369258RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000483530ENST00000369259RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000550536ENST00000361293RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000550536ENST00000369258RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5CDS-intronENST00000550536ENST00000369259RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5UTR-3CDSENST00000325555ENST00000431239RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5UTR-3UTRENST00000325555ENST00000467213RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5UTR-intronENST00000325555ENST00000361293RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5UTR-intronENST00000325555ENST00000369258RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
5UTR-intronENST00000325555ENST00000369259RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
In-frameENST00000247833ENST00000431239RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
In-frameENST00000362025ENST00000431239RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
In-frameENST00000378815ENST00000431239RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
In-frameENST00000483530ENST00000431239RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
In-frameENST00000550536ENST00000431239RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-3CDSENST00000550847ENST00000431239RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-3CDSENST00000551641ENST00000431239RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-3CDSENST00000553099ENST00000431239RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-3UTRENST00000550847ENST00000467213RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-3UTRENST00000551641ENST00000467213RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-3UTRENST00000553099ENST00000467213RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-intronENST00000550847ENST00000361293RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-intronENST00000550847ENST00000369258RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-intronENST00000550847ENST00000369259RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-intronENST00000551641ENST00000361293RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-intronENST00000551641ENST00000369258RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-intronENST00000551641ENST00000369259RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-intronENST00000553099ENST00000361293RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-intronENST00000553099ENST00000369258RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+
intron-intronENST00000553099ENST00000369259RAB3IPchr12

70150443

+CHD1Lchr1

146736080

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000247833RAB3IPchr1270150443+ENST00000431239CHD1Lchr1146736080+29738863162721801
ENST00000378815RAB3IPchr1270150443+ENST00000431239CHD1Lchr1146736080+27927051352540801
ENST00000483530RAB3IPchr1270150443+ENST00000431239CHD1Lchr1146736080+27927051352540801
ENST00000550536RAB3IPchr1270150443+ENST00000431239CHD1Lchr1146736080+310210154452850801
ENST00000362025RAB3IPchr1270150443+ENST00000431239CHD1Lchr1146736080+309210054352840801

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000247833ENST00000431239RAB3IPchr1270150443+CHD1Lchr1146736080+0.0026809360.99731904
ENST00000378815ENST00000431239RAB3IPchr1270150443+CHD1Lchr1146736080+0.0022856590.9977144
ENST00000483530ENST00000431239RAB3IPchr1270150443+CHD1Lchr1146736080+0.0022856590.9977144
ENST00000550536ENST00000431239RAB3IPchr1270150443+CHD1Lchr1146736080+0.0012840690.998716
ENST00000362025ENST00000431239RAB3IPchr1270150443+CHD1Lchr1146736080+0.0013020250.998698

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Fusion Genomic Features for RAB3IP-CHD1L


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RAB3IPchr1270150443+CHD1Lchr1146736080+4.48E-060.99999547
RAB3IPchr1270150443+CHD1Lchr1146736080+4.48E-060.99999547

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for RAB3IP-CHD1L


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:70150443/chr1:146736080)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CHD1L

Q86WJ1

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: DNA helicase which plays a role in chromatin-remodeling following DNA damage (PubMed:19661379, PubMed:29220653). Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair (PubMed:19661379). Able to catalyze nucleosome sliding in an ATP-dependent manner (PubMed:19661379). Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding (PubMed:19661379, PubMed:29220653). {ECO:0000269|PubMed:19661379, ECO:0000269|PubMed:29220653}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000369258523638_675192898.0Coiled coilOntology_term=ECO:0000255
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000369259017638_6750694.0Coiled coilOntology_term=ECO:0000255
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000431239520638_675192804.0Coiled coilOntology_term=ECO:0000255
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000369258523351_513192898.0DomainHelicase C-terminal
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000369258523704_897192898.0DomainMacro
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000369259017351_5130694.0DomainHelicase C-terminal
TgeneCHD1Lchr12:70150443chr1:146736080ENST0000036925901758_2230694.0DomainHelicase ATP-binding
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000369259017704_8970694.0DomainMacro
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000431239520351_513192804.0DomainHelicase C-terminal
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000431239520704_897192804.0DomainMacro
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000369259017174_1770694.0MotifNote=DEAH box
TgeneCHD1Lchr12:70150443chr1:146736080ENST0000036925901771_780694.0Nucleotide bindingATP
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000369258523615_673192898.0RegionRequired for helicase activity
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000369259017615_6730694.0RegionRequired for helicase activity
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000431239520615_673192804.0RegionRequired for helicase activity

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCHD1Lchr12:70150443chr1:146736080ENST0000036925852358_223192898.0DomainHelicase ATP-binding
TgeneCHD1Lchr12:70150443chr1:146736080ENST0000043123952058_223192804.0DomainHelicase ATP-binding
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000369258523174_177192898.0MotifNote=DEAH box
TgeneCHD1Lchr12:70150443chr1:146736080ENST00000431239520174_177192804.0MotifNote=DEAH box
TgeneCHD1Lchr12:70150443chr1:146736080ENST0000036925852371_78192898.0Nucleotide bindingATP
TgeneCHD1Lchr12:70150443chr1:146736080ENST0000043123952071_78192804.0Nucleotide bindingATP


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Fusion Gene Sequence for RAB3IP-CHD1L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>71387_71387_1_RAB3IP-CHD1L_RAB3IP_chr12_70150443_ENST00000247833_CHD1L_chr1_146736080_ENST00000431239_length(transcript)=2973nt_BP=886nt
GGGCCAGGGCCGTGACACCTGCGACGAGCCCCGCCTGGCGCCAGGGGGCGCGGAAGCGCGTCCGCCCCCAGGCCCCATGCCGGGCTCGCC
CCGCCCCTGCCGGCCACACCCCCCTACCCCGCCCTCCCTCCGTGAGGACCGGCCGCTCCCGGCTCCCGGCCCCCGGCCCCGCTTCCGGCG
CAGGCGCAGTCCCGCGTTCCCTCGGCGGCTGCCGGCGTAGTGAGCCCGCCGCCGTGGAGTGTAGCGGAAAGGGCTCGCCGTCCTCCTCCG
TTTCTCGCTGCTTCGGGACGCGCTCTCTGCGGCTCTGTGAGCGCCCCTGAGCGCCGGCAGCGGCCGCGGTGGGTTCTTCAGGTTATCTTA
TGATGAGGCTTTTGCTATGGCTAATGATCCCTTGGAAGGCTTCCATGAAGTAAACCTTGCTTCACCTACTTCTCCGGACCTTCTTGGTGT
GTATGAATCAGGAACTCAAGAGCAGACTACCTCACCAAGTGTCATCTACCGGCCACACCCTTCAGCTTTATCCTCTGTACCTATCCAGGC
AAATGCATTAGATGTTTCTGAACTTCCTACACAACCCGTGTATTCATCCCCCAGACGTTTAAATTGTGCGGAAATATCTAGTATCAGCTT
TCATGTTACAGACCCAGCCCCTTGCTCTACCTCTGGAGTCACAGCTGGATTAACTAAATTAACTACAAGAAAGGACAACTATAATGCAGA
GAGAGAGTTTTTACAGGGTGCTACTATAACAGAGGCTTGCGATGGCAGTGATGATATTTTTGGGTTGAGTACTGATAGTCTGTCTCGTTT
ACGAAGCCCATCTGTTTTGGAAGTTAGAGAAAAGGGCTATGAACGATTAAAAGAAGAACTCGCAAAAGCTCAGAGGTTCTCAGTAGTCTT
CAGTCTCCTGTTGACCGGAACTCCCATCCAGAACAGCCTCCAAGAGCTCTACTCCCTCCTCAGTTTTGTGGAGCCTGATCTCTTTTCCAA
GGAAGAGGTGGGAGATTTTATTCAACGCTACCAGGATATTGAGAAAGAATCTGAGTCAGCAAGTGAACTGCACAAACTCTTGCAGCCATT
TCTGCTGAGGCGAGTGAAAGCTGAGGTAGCTACAGAGCTTCCCAAGAAGACAGAAGTAGTGATATACCATGGCATGTCAGCATTGCAGAA
GAAATACTACAAGGCCATTTTGATGAAAGACCTAGATGCATTTGAAAATGAGACGGCAAAGAAAGTTAAACTACAGAACATTTTGTCCCA
GCTTCGAAAGTGTGTGGATCACCCATATTTGTTTGATGGTGGAGTTGGCATGAACTTAACAGCAGCAGATACTGTGATTTTTGTTGACAG
TGACTTTAATCCTCAGAATGACTTGCAAGCAGCTGCCAGGGCTCATCGCATTGGCCAAAACAAGTCTGTTAAAGTTATTCGGCTGATTGG
TCGAGACACTGTGGAAGAAATAGTCTATAGGAAAGCAGCCTCCAAACTGCAGCTCACCAACATGATCATAGAAGGAGGCCATTTTACTCT
GGGAGCCCAGAAACCCGCTGCCGATGCTGACCTCCAGTTGAGTGAGATACTCAAATTTGGTTTGGATAAACTGCTGGCCTCTGAGGGGAG
CACCATGGATGAAATAGACCTGGAGTCCATACTGGGAGAAACAAAAGATGGCCAGTGGGTCTCTGATGCCTTGCCTGCAGCAGAAGGAGG
GAGCAGAGATCAAGAGGAAGGAAAAAATCATATGTACTTATTTGAAGGTAAAGATTATTCTAAAGAGCCCAGTAAGGAAGACAGAAAATC
ATTTGAACAACTGGTAAACCTTCAGAAAACCCTTTTGGAGAAAGCTAGTCAAGAGGGCCGATCACTCCGAAATAAAGGCAGTGTTCTCAT
CCCAGGCCTTGTGGAGGGATCTACCAAAAGGAAGCGGGTTCTGAGTCCAGAAGAGCTGGAGGACAGACAGAAGAAAAGACAAGAAGCAGC
TGCCAAGAGAAGGAGACTCATAGAGGAGAAGAAGAGGCAAAAGGAAGAGGCTGAACATAAGAAAAAGATGGCCTGGTGGGAATCCAACAA
TTACCAGTCCTTCTGCCTGCCCTCTGAGGAGAGCGAGCCAGAGGACCTTGAGAATGGGGAAGAGAGCTCTGCTGAGCTGGATTACCAAGA
CCCAGATGCTACTTCCCTCAAGTACGTTAGTGGTGATGTCACCCACCCTCAGGCTGGGGCCGAGGATGCTCTCATTGTGCACTGCGTAGA
TGACTCTGGCCACTGGGGCAGAGGTGGTTTATTTACAGCTCTGGAAAAGCGATCCGCTGAGCCAAGAAAAATATATGAGCTGGCTGGGAA
AATGAAAGACCTGAGTTTGGGAGGTGTCCTTTTATTTCCTGTTGATGATAAAGAATCAAGAAACAAAGGGCAAGATTTGTTGGCCTTGAT
TGTGGCTCAGCATCGTGATCGTTCCAATGTCCTGTCTGGCATTAAGATGGCAGCCCTAGAAGAGGGCCTGAAGAAGATATTTTTAGCAGC
AAAAAAGAAGAAAGCAAGTGTTCATCTTCCACGTATTGGACATGCCACGAAAGGTTTTAACTGGTATGGTACTGAGCGACTTATTCGGAA
ACATCTGGCTGCAAGAGGCATCCCAACTTACATATATTATTTTCCTAGAAGCAAGTCTGCTGTCCTTCATGCACAGTCTTCATCTTCCTC
CTCAAGACAGCTGGTGCCTTAAGAATTGGCCCAGCCTCAGATCCTGTCTTTAGCAACCAGCTAATATTTACCCAGAGGTACTGCAATAGA
GTATTTCAAAATGGAATCAGGATCTGGTGGGCCTCAGAAATTGTCTCTTTTCTGAGTTTCAATTTGGTTCTCCTGGATGTTTTGCTCTGT
TTTGGTACCTGTAATATAGGGAAACACAACTTTTTTTGGGAAAGCCCTTTGACCCCAGCTTGCTAGTTGCATAATAATAAATTTTCTGTT

>71387_71387_1_RAB3IP-CHD1L_RAB3IP_chr12_70150443_ENST00000247833_CHD1L_chr1_146736080_ENST00000431239_length(amino acids)=801AA_BP=190
MSAGSGRGGFFRLSYDEAFAMANDPLEGFHEVNLASPTSPDLLGVYESGTQEQTTSPSVIYRPHPSALSSVPIQANALDVSELPTQPVYS
SPRRLNCAEISSISFHVTDPAPCSTSGVTAGLTKLTTRKDNYNAEREFLQGATITEACDGSDDIFGLSTDSLSRLRSPSVLEVREKGYER
LKEELAKAQRFSVVFSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELPK
KTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVKLQNILSQLRKCVDHPYLFDGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAH
RIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETK
DGQWVSDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQEGRSLRNKGSVLIPGLVEGSTKRKRVLS
PEELEDRQKKRQEAAAKRRRLIEEKKRQKEEAEHKKKMAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYVSGDVTH
PQAGAEDALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKDLSLGGVLLFPVDDKESRNKGQDLLALIVAQHRDRSNVLSGIK

--------------------------------------------------------------
>71387_71387_2_RAB3IP-CHD1L_RAB3IP_chr12_70150443_ENST00000362025_CHD1L_chr1_146736080_ENST00000431239_length(transcript)=3092nt_BP=1005nt
GGTTACCTGGCGGCGGGCGGGCGCGGCCGGGAGCGGAGGGCCGCGGTCGCGAAGAGGATGAAGAGAGAGTTCCCGAACAAGTCGGAAGCA
GCTCACAACACCGGACGCCGCGCGGCAGGGCTGTGGACCTGGGGTGGTTTCGTGTCCCAGTCTTAGGAAACTACGCGCGAGGCACCGTGC
TGAGGCGTAGAGGTCACCCTCGGGAGGTTTCGGTGAAACCTGGTGGGAAATTCCGGGCAGGCGCCCGGAGTCGCGCCCAAGTAGGCAGCT
CCGTGCCGCCAGACTTGTGTTCGGGGGAGTTGAGACGAACTGCACGGGTGGGATTGCATGGCTCTGCCCTCCCAGCGTTGACAACTCGCC
CCGACCGCCCAGGAAGCGCGAGCTTACTGGCTCCAGAAGTGATGATGCTGGGTGGAAGTCGCAGCATGTGAAGAGTTGCCGGTTGTTATG
GGATTAAAAAAGATGAAAGGGTTATCTTATGATGAGGCTTTTGCTATGGCTAATGATCCCTTGGAAGGCTTCCATGAAGTAAACCTTGCT
TCACCTACTTCTCCGGACCTTCTTGGTGTGTATGAATCAGGAACTCAAGAGCAGACTACCTCACCAAGTGTCATCTACCGGCCACACCCT
TCAGCTTTATCCTCTGTACCTATCCAGGCAAATGCATTAGATGTTTCTGAACTTCCTACACAACCCGTGTATTCATCCCCCAGACGTTTA
AATTGTGCGGAAATATCTAGTATCAGCTTTCATGTTACAGACCCAGCCCCTTGCTCTACCTCTGGAGTCACAGCTGGATTAACTAAATTA
ACTACAAGAAAGGACAACTATAATGCAGAGAGAGAGTTTTTACAGGGTGCTACTATAACAGAGGCTTGCGATGGCAGTGATGATATTTTT
GGGTTGAGTACTGATAGTCTGTCTCGTTTACGAAGCCCATCTGTTTTGGAAGTTAGAGAAAAGGGCTATGAACGATTAAAAGAAGAACTC
GCAAAAGCTCAGAGGTTCTCAGTAGTCTTCAGTCTCCTGTTGACCGGAACTCCCATCCAGAACAGCCTCCAAGAGCTCTACTCCCTCCTC
AGTTTTGTGGAGCCTGATCTCTTTTCCAAGGAAGAGGTGGGAGATTTTATTCAACGCTACCAGGATATTGAGAAAGAATCTGAGTCAGCA
AGTGAACTGCACAAACTCTTGCAGCCATTTCTGCTGAGGCGAGTGAAAGCTGAGGTAGCTACAGAGCTTCCCAAGAAGACAGAAGTAGTG
ATATACCATGGCATGTCAGCATTGCAGAAGAAATACTACAAGGCCATTTTGATGAAAGACCTAGATGCATTTGAAAATGAGACGGCAAAG
AAAGTTAAACTACAGAACATTTTGTCCCAGCTTCGAAAGTGTGTGGATCACCCATATTTGTTTGATGGTGGAGTTGGCATGAACTTAACA
GCAGCAGATACTGTGATTTTTGTTGACAGTGACTTTAATCCTCAGAATGACTTGCAAGCAGCTGCCAGGGCTCATCGCATTGGCCAAAAC
AAGTCTGTTAAAGTTATTCGGCTGATTGGTCGAGACACTGTGGAAGAAATAGTCTATAGGAAAGCAGCCTCCAAACTGCAGCTCACCAAC
ATGATCATAGAAGGAGGCCATTTTACTCTGGGAGCCCAGAAACCCGCTGCCGATGCTGACCTCCAGTTGAGTGAGATACTCAAATTTGGT
TTGGATAAACTGCTGGCCTCTGAGGGGAGCACCATGGATGAAATAGACCTGGAGTCCATACTGGGAGAAACAAAAGATGGCCAGTGGGTC
TCTGATGCCTTGCCTGCAGCAGAAGGAGGGAGCAGAGATCAAGAGGAAGGAAAAAATCATATGTACTTATTTGAAGGTAAAGATTATTCT
AAAGAGCCCAGTAAGGAAGACAGAAAATCATTTGAACAACTGGTAAACCTTCAGAAAACCCTTTTGGAGAAAGCTAGTCAAGAGGGCCGA
TCACTCCGAAATAAAGGCAGTGTTCTCATCCCAGGCCTTGTGGAGGGATCTACCAAAAGGAAGCGGGTTCTGAGTCCAGAAGAGCTGGAG
GACAGACAGAAGAAAAGACAAGAAGCAGCTGCCAAGAGAAGGAGACTCATAGAGGAGAAGAAGAGGCAAAAGGAAGAGGCTGAACATAAG
AAAAAGATGGCCTGGTGGGAATCCAACAATTACCAGTCCTTCTGCCTGCCCTCTGAGGAGAGCGAGCCAGAGGACCTTGAGAATGGGGAA
GAGAGCTCTGCTGAGCTGGATTACCAAGACCCAGATGCTACTTCCCTCAAGTACGTTAGTGGTGATGTCACCCACCCTCAGGCTGGGGCC
GAGGATGCTCTCATTGTGCACTGCGTAGATGACTCTGGCCACTGGGGCAGAGGTGGTTTATTTACAGCTCTGGAAAAGCGATCCGCTGAG
CCAAGAAAAATATATGAGCTGGCTGGGAAAATGAAAGACCTGAGTTTGGGAGGTGTCCTTTTATTTCCTGTTGATGATAAAGAATCAAGA
AACAAAGGGCAAGATTTGTTGGCCTTGATTGTGGCTCAGCATCGTGATCGTTCCAATGTCCTGTCTGGCATTAAGATGGCAGCCCTAGAA
GAGGGCCTGAAGAAGATATTTTTAGCAGCAAAAAAGAAGAAAGCAAGTGTTCATCTTCCACGTATTGGACATGCCACGAAAGGTTTTAAC
TGGTATGGTACTGAGCGACTTATTCGGAAACATCTGGCTGCAAGAGGCATCCCAACTTACATATATTATTTTCCTAGAAGCAAGTCTGCT
GTCCTTCATGCACAGTCTTCATCTTCCTCCTCAAGACAGCTGGTGCCTTAAGAATTGGCCCAGCCTCAGATCCTGTCTTTAGCAACCAGC
TAATATTTACCCAGAGGTACTGCAATAGAGTATTTCAAAATGGAATCAGGATCTGGTGGGCCTCAGAAATTGTCTCTTTTCTGAGTTTCA
ATTTGGTTCTCCTGGATGTTTTGCTCTGTTTTGGTACCTGTAATATAGGGAAACACAACTTTTTTTGGGAAAGCCCTTTGACCCCAGCTT

>71387_71387_2_RAB3IP-CHD1L_RAB3IP_chr12_70150443_ENST00000362025_CHD1L_chr1_146736080_ENST00000431239_length(amino acids)=801AA_BP=190
MPVVMGLKKMKGLSYDEAFAMANDPLEGFHEVNLASPTSPDLLGVYESGTQEQTTSPSVIYRPHPSALSSVPIQANALDVSELPTQPVYS
SPRRLNCAEISSISFHVTDPAPCSTSGVTAGLTKLTTRKDNYNAEREFLQGATITEACDGSDDIFGLSTDSLSRLRSPSVLEVREKGYER
LKEELAKAQRFSVVFSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELPK
KTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVKLQNILSQLRKCVDHPYLFDGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAH
RIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETK
DGQWVSDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQEGRSLRNKGSVLIPGLVEGSTKRKRVLS
PEELEDRQKKRQEAAAKRRRLIEEKKRQKEEAEHKKKMAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYVSGDVTH
PQAGAEDALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKDLSLGGVLLFPVDDKESRNKGQDLLALIVAQHRDRSNVLSGIK

--------------------------------------------------------------
>71387_71387_3_RAB3IP-CHD1L_RAB3IP_chr12_70150443_ENST00000378815_CHD1L_chr1_146736080_ENST00000431239_length(transcript)=2792nt_BP=705nt
AGGCGCAGTCCCGCGTTCCCTCGGCGGCTGCCGGCGTAGTGAGCCCGCCGCCGTGGAGTGTAGCGGAAAGGGCTCGCCGTCCTCCTCCGT
TTCTCGCTGCTTCGGGACGCGCTCTCTGCGGCTCTGTGAGCGCCCCTGAGCGCCGGCAGCGGCCGCGGTGGGTTCTTCAGGTTATCTTAT
GATGAGGCTTTTGCTATGGCTAATGATCCCTTGGAAGGCTTCCATGAAGTAAACCTTGCTTCACCTACTTCTCCGGACCTTCTTGGTGTG
TATGAATCAGGAACTCAAGAGCAGACTACCTCACCAAGTGTCATCTACCGGCCACACCCTTCAGCTTTATCCTCTGTACCTATCCAGGCA
AATGCATTAGATGTTTCTGAACTTCCTACACAACCCGTGTATTCATCCCCCAGACGTTTAAATTGTGCGGAAATATCTAGTATCAGCTTT
CATGTTACAGACCCAGCCCCTTGCTCTACCTCTGGAGTCACAGCTGGATTAACTAAATTAACTACAAGAAAGGACAACTATAATGCAGAG
AGAGAGTTTTTACAGGGTGCTACTATAACAGAGGCTTGCGATGGCAGTGATGATATTTTTGGGTTGAGTACTGATAGTCTGTCTCGTTTA
CGAAGCCCATCTGTTTTGGAAGTTAGAGAAAAGGGCTATGAACGATTAAAAGAAGAACTCGCAAAAGCTCAGAGGTTCTCAGTAGTCTTC
AGTCTCCTGTTGACCGGAACTCCCATCCAGAACAGCCTCCAAGAGCTCTACTCCCTCCTCAGTTTTGTGGAGCCTGATCTCTTTTCCAAG
GAAGAGGTGGGAGATTTTATTCAACGCTACCAGGATATTGAGAAAGAATCTGAGTCAGCAAGTGAACTGCACAAACTCTTGCAGCCATTT
CTGCTGAGGCGAGTGAAAGCTGAGGTAGCTACAGAGCTTCCCAAGAAGACAGAAGTAGTGATATACCATGGCATGTCAGCATTGCAGAAG
AAATACTACAAGGCCATTTTGATGAAAGACCTAGATGCATTTGAAAATGAGACGGCAAAGAAAGTTAAACTACAGAACATTTTGTCCCAG
CTTCGAAAGTGTGTGGATCACCCATATTTGTTTGATGGTGGAGTTGGCATGAACTTAACAGCAGCAGATACTGTGATTTTTGTTGACAGT
GACTTTAATCCTCAGAATGACTTGCAAGCAGCTGCCAGGGCTCATCGCATTGGCCAAAACAAGTCTGTTAAAGTTATTCGGCTGATTGGT
CGAGACACTGTGGAAGAAATAGTCTATAGGAAAGCAGCCTCCAAACTGCAGCTCACCAACATGATCATAGAAGGAGGCCATTTTACTCTG
GGAGCCCAGAAACCCGCTGCCGATGCTGACCTCCAGTTGAGTGAGATACTCAAATTTGGTTTGGATAAACTGCTGGCCTCTGAGGGGAGC
ACCATGGATGAAATAGACCTGGAGTCCATACTGGGAGAAACAAAAGATGGCCAGTGGGTCTCTGATGCCTTGCCTGCAGCAGAAGGAGGG
AGCAGAGATCAAGAGGAAGGAAAAAATCATATGTACTTATTTGAAGGTAAAGATTATTCTAAAGAGCCCAGTAAGGAAGACAGAAAATCA
TTTGAACAACTGGTAAACCTTCAGAAAACCCTTTTGGAGAAAGCTAGTCAAGAGGGCCGATCACTCCGAAATAAAGGCAGTGTTCTCATC
CCAGGCCTTGTGGAGGGATCTACCAAAAGGAAGCGGGTTCTGAGTCCAGAAGAGCTGGAGGACAGACAGAAGAAAAGACAAGAAGCAGCT
GCCAAGAGAAGGAGACTCATAGAGGAGAAGAAGAGGCAAAAGGAAGAGGCTGAACATAAGAAAAAGATGGCCTGGTGGGAATCCAACAAT
TACCAGTCCTTCTGCCTGCCCTCTGAGGAGAGCGAGCCAGAGGACCTTGAGAATGGGGAAGAGAGCTCTGCTGAGCTGGATTACCAAGAC
CCAGATGCTACTTCCCTCAAGTACGTTAGTGGTGATGTCACCCACCCTCAGGCTGGGGCCGAGGATGCTCTCATTGTGCACTGCGTAGAT
GACTCTGGCCACTGGGGCAGAGGTGGTTTATTTACAGCTCTGGAAAAGCGATCCGCTGAGCCAAGAAAAATATATGAGCTGGCTGGGAAA
ATGAAAGACCTGAGTTTGGGAGGTGTCCTTTTATTTCCTGTTGATGATAAAGAATCAAGAAACAAAGGGCAAGATTTGTTGGCCTTGATT
GTGGCTCAGCATCGTGATCGTTCCAATGTCCTGTCTGGCATTAAGATGGCAGCCCTAGAAGAGGGCCTGAAGAAGATATTTTTAGCAGCA
AAAAAGAAGAAAGCAAGTGTTCATCTTCCACGTATTGGACATGCCACGAAAGGTTTTAACTGGTATGGTACTGAGCGACTTATTCGGAAA
CATCTGGCTGCAAGAGGCATCCCAACTTACATATATTATTTTCCTAGAAGCAAGTCTGCTGTCCTTCATGCACAGTCTTCATCTTCCTCC
TCAAGACAGCTGGTGCCTTAAGAATTGGCCCAGCCTCAGATCCTGTCTTTAGCAACCAGCTAATATTTACCCAGAGGTACTGCAATAGAG
TATTTCAAAATGGAATCAGGATCTGGTGGGCCTCAGAAATTGTCTCTTTTCTGAGTTTCAATTTGGTTCTCCTGGATGTTTTGCTCTGTT
TTGGTACCTGTAATATAGGGAAACACAACTTTTTTTGGGAAAGCCCTTTGACCCCAGCTTGCTAGTTGCATAATAATAAATTTTCTGTTC

>71387_71387_3_RAB3IP-CHD1L_RAB3IP_chr12_70150443_ENST00000378815_CHD1L_chr1_146736080_ENST00000431239_length(amino acids)=801AA_BP=190
MSAGSGRGGFFRLSYDEAFAMANDPLEGFHEVNLASPTSPDLLGVYESGTQEQTTSPSVIYRPHPSALSSVPIQANALDVSELPTQPVYS
SPRRLNCAEISSISFHVTDPAPCSTSGVTAGLTKLTTRKDNYNAEREFLQGATITEACDGSDDIFGLSTDSLSRLRSPSVLEVREKGYER
LKEELAKAQRFSVVFSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELPK
KTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVKLQNILSQLRKCVDHPYLFDGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAH
RIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETK
DGQWVSDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQEGRSLRNKGSVLIPGLVEGSTKRKRVLS
PEELEDRQKKRQEAAAKRRRLIEEKKRQKEEAEHKKKMAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYVSGDVTH
PQAGAEDALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKDLSLGGVLLFPVDDKESRNKGQDLLALIVAQHRDRSNVLSGIK

--------------------------------------------------------------
>71387_71387_4_RAB3IP-CHD1L_RAB3IP_chr12_70150443_ENST00000483530_CHD1L_chr1_146736080_ENST00000431239_length(transcript)=2792nt_BP=705nt
AGGCGCAGTCCCGCGTTCCCTCGGCGGCTGCCGGCGTAGTGAGCCCGCCGCCGTGGAGTGTAGCGGAAAGGGCTCGCCGTCCTCCTCCGT
TTCTCGCTGCTTCGGGACGCGCTCTCTGCGGCTCTGTGAGCGCCCCTGAGCGCCGGCAGCGGCCGCGGTGGGTTCTTCAGGTTATCTTAT
GATGAGGCTTTTGCTATGGCTAATGATCCCTTGGAAGGCTTCCATGAAGTAAACCTTGCTTCACCTACTTCTCCGGACCTTCTTGGTGTG
TATGAATCAGGAACTCAAGAGCAGACTACCTCACCAAGTGTCATCTACCGGCCACACCCTTCAGCTTTATCCTCTGTACCTATCCAGGCA
AATGCATTAGATGTTTCTGAACTTCCTACACAACCCGTGTATTCATCCCCCAGACGTTTAAATTGTGCGGAAATATCTAGTATCAGCTTT
CATGTTACAGACCCAGCCCCTTGCTCTACCTCTGGAGTCACAGCTGGATTAACTAAATTAACTACAAGAAAGGACAACTATAATGCAGAG
AGAGAGTTTTTACAGGGTGCTACTATAACAGAGGCTTGCGATGGCAGTGATGATATTTTTGGGTTGAGTACTGATAGTCTGTCTCGTTTA
CGAAGCCCATCTGTTTTGGAAGTTAGAGAAAAGGGCTATGAACGATTAAAAGAAGAACTCGCAAAAGCTCAGAGGTTCTCAGTAGTCTTC
AGTCTCCTGTTGACCGGAACTCCCATCCAGAACAGCCTCCAAGAGCTCTACTCCCTCCTCAGTTTTGTGGAGCCTGATCTCTTTTCCAAG
GAAGAGGTGGGAGATTTTATTCAACGCTACCAGGATATTGAGAAAGAATCTGAGTCAGCAAGTGAACTGCACAAACTCTTGCAGCCATTT
CTGCTGAGGCGAGTGAAAGCTGAGGTAGCTACAGAGCTTCCCAAGAAGACAGAAGTAGTGATATACCATGGCATGTCAGCATTGCAGAAG
AAATACTACAAGGCCATTTTGATGAAAGACCTAGATGCATTTGAAAATGAGACGGCAAAGAAAGTTAAACTACAGAACATTTTGTCCCAG
CTTCGAAAGTGTGTGGATCACCCATATTTGTTTGATGGTGGAGTTGGCATGAACTTAACAGCAGCAGATACTGTGATTTTTGTTGACAGT
GACTTTAATCCTCAGAATGACTTGCAAGCAGCTGCCAGGGCTCATCGCATTGGCCAAAACAAGTCTGTTAAAGTTATTCGGCTGATTGGT
CGAGACACTGTGGAAGAAATAGTCTATAGGAAAGCAGCCTCCAAACTGCAGCTCACCAACATGATCATAGAAGGAGGCCATTTTACTCTG
GGAGCCCAGAAACCCGCTGCCGATGCTGACCTCCAGTTGAGTGAGATACTCAAATTTGGTTTGGATAAACTGCTGGCCTCTGAGGGGAGC
ACCATGGATGAAATAGACCTGGAGTCCATACTGGGAGAAACAAAAGATGGCCAGTGGGTCTCTGATGCCTTGCCTGCAGCAGAAGGAGGG
AGCAGAGATCAAGAGGAAGGAAAAAATCATATGTACTTATTTGAAGGTAAAGATTATTCTAAAGAGCCCAGTAAGGAAGACAGAAAATCA
TTTGAACAACTGGTAAACCTTCAGAAAACCCTTTTGGAGAAAGCTAGTCAAGAGGGCCGATCACTCCGAAATAAAGGCAGTGTTCTCATC
CCAGGCCTTGTGGAGGGATCTACCAAAAGGAAGCGGGTTCTGAGTCCAGAAGAGCTGGAGGACAGACAGAAGAAAAGACAAGAAGCAGCT
GCCAAGAGAAGGAGACTCATAGAGGAGAAGAAGAGGCAAAAGGAAGAGGCTGAACATAAGAAAAAGATGGCCTGGTGGGAATCCAACAAT
TACCAGTCCTTCTGCCTGCCCTCTGAGGAGAGCGAGCCAGAGGACCTTGAGAATGGGGAAGAGAGCTCTGCTGAGCTGGATTACCAAGAC
CCAGATGCTACTTCCCTCAAGTACGTTAGTGGTGATGTCACCCACCCTCAGGCTGGGGCCGAGGATGCTCTCATTGTGCACTGCGTAGAT
GACTCTGGCCACTGGGGCAGAGGTGGTTTATTTACAGCTCTGGAAAAGCGATCCGCTGAGCCAAGAAAAATATATGAGCTGGCTGGGAAA
ATGAAAGACCTGAGTTTGGGAGGTGTCCTTTTATTTCCTGTTGATGATAAAGAATCAAGAAACAAAGGGCAAGATTTGTTGGCCTTGATT
GTGGCTCAGCATCGTGATCGTTCCAATGTCCTGTCTGGCATTAAGATGGCAGCCCTAGAAGAGGGCCTGAAGAAGATATTTTTAGCAGCA
AAAAAGAAGAAAGCAAGTGTTCATCTTCCACGTATTGGACATGCCACGAAAGGTTTTAACTGGTATGGTACTGAGCGACTTATTCGGAAA
CATCTGGCTGCAAGAGGCATCCCAACTTACATATATTATTTTCCTAGAAGCAAGTCTGCTGTCCTTCATGCACAGTCTTCATCTTCCTCC
TCAAGACAGCTGGTGCCTTAAGAATTGGCCCAGCCTCAGATCCTGTCTTTAGCAACCAGCTAATATTTACCCAGAGGTACTGCAATAGAG
TATTTCAAAATGGAATCAGGATCTGGTGGGCCTCAGAAATTGTCTCTTTTCTGAGTTTCAATTTGGTTCTCCTGGATGTTTTGCTCTGTT
TTGGTACCTGTAATATAGGGAAACACAACTTTTTTTGGGAAAGCCCTTTGACCCCAGCTTGCTAGTTGCATAATAATAAATTTTCTGTTC

>71387_71387_4_RAB3IP-CHD1L_RAB3IP_chr12_70150443_ENST00000483530_CHD1L_chr1_146736080_ENST00000431239_length(amino acids)=801AA_BP=190
MSAGSGRGGFFRLSYDEAFAMANDPLEGFHEVNLASPTSPDLLGVYESGTQEQTTSPSVIYRPHPSALSSVPIQANALDVSELPTQPVYS
SPRRLNCAEISSISFHVTDPAPCSTSGVTAGLTKLTTRKDNYNAEREFLQGATITEACDGSDDIFGLSTDSLSRLRSPSVLEVREKGYER
LKEELAKAQRFSVVFSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELPK
KTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVKLQNILSQLRKCVDHPYLFDGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAH
RIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETK
DGQWVSDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQEGRSLRNKGSVLIPGLVEGSTKRKRVLS
PEELEDRQKKRQEAAAKRRRLIEEKKRQKEEAEHKKKMAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYVSGDVTH
PQAGAEDALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKDLSLGGVLLFPVDDKESRNKGQDLLALIVAQHRDRSNVLSGIK

--------------------------------------------------------------
>71387_71387_5_RAB3IP-CHD1L_RAB3IP_chr12_70150443_ENST00000550536_CHD1L_chr1_146736080_ENST00000431239_length(transcript)=3102nt_BP=1015nt
GAGTCCAGCGGGTTACCTGGCGGCGGGCGGGCGCGGCCGGGAGCGGAGGGCCGCGGTCGCGAAGAGGATGAAGAGAGAGTTCCCGAACAA
GTCGGAAGCAGCTCACAACACCGGACGCCGCGCGGCAGGGCTGTGGACCTGGGGTGGTTTCGTGTCCCAGTCTTAGGAAACTACGCGCGA
GGCACCGTGCTGAGGCGTAGAGGTCACCCTCGGGAGGTTTCGGTGAAACCTGGTGGGAAATTCCGGGCAGGCGCCCGGAGTCGCGCCCAA
GTAGGCAGCTCCGTGCCGCCAGACTTGTGTTCGGGGGAGTTGAGACGAACTGCACGGGTGGGATTGCATGGCTCTGCCCTCCCAGCGTTG
ACAACTCGCCCCGACCGCCCAGGAAGCGCGAGCTTACTGGCTCCAGAAGTGATGATGCTGGGTGGAAGTCGCAGCATGTGAAGAGTTGCC
GGTTGTTATGGGATTAAAAAAGATGAAAGGGTTATCTTATGATGAGGCTTTTGCTATGGCTAATGATCCCTTGGAAGGCTTCCATGAAGT
AAACCTTGCTTCACCTACTTCTCCGGACCTTCTTGGTGTGTATGAATCAGGAACTCAAGAGCAGACTACCTCACCAAGTGTCATCTACCG
GCCACACCCTTCAGCTTTATCCTCTGTACCTATCCAGGCAAATGCATTAGATGTTTCTGAACTTCCTACACAACCCGTGTATTCATCCCC
CAGACGTTTAAATTGTGCGGAAATATCTAGTATCAGCTTTCATGTTACAGACCCAGCCCCTTGCTCTACCTCTGGAGTCACAGCTGGATT
AACTAAATTAACTACAAGAAAGGACAACTATAATGCAGAGAGAGAGTTTTTACAGGGTGCTACTATAACAGAGGCTTGCGATGGCAGTGA
TGATATTTTTGGGTTGAGTACTGATAGTCTGTCTCGTTTACGAAGCCCATCTGTTTTGGAAGTTAGAGAAAAGGGCTATGAACGATTAAA
AGAAGAACTCGCAAAAGCTCAGAGGTTCTCAGTAGTCTTCAGTCTCCTGTTGACCGGAACTCCCATCCAGAACAGCCTCCAAGAGCTCTA
CTCCCTCCTCAGTTTTGTGGAGCCTGATCTCTTTTCCAAGGAAGAGGTGGGAGATTTTATTCAACGCTACCAGGATATTGAGAAAGAATC
TGAGTCAGCAAGTGAACTGCACAAACTCTTGCAGCCATTTCTGCTGAGGCGAGTGAAAGCTGAGGTAGCTACAGAGCTTCCCAAGAAGAC
AGAAGTAGTGATATACCATGGCATGTCAGCATTGCAGAAGAAATACTACAAGGCCATTTTGATGAAAGACCTAGATGCATTTGAAAATGA
GACGGCAAAGAAAGTTAAACTACAGAACATTTTGTCCCAGCTTCGAAAGTGTGTGGATCACCCATATTTGTTTGATGGTGGAGTTGGCAT
GAACTTAACAGCAGCAGATACTGTGATTTTTGTTGACAGTGACTTTAATCCTCAGAATGACTTGCAAGCAGCTGCCAGGGCTCATCGCAT
TGGCCAAAACAAGTCTGTTAAAGTTATTCGGCTGATTGGTCGAGACACTGTGGAAGAAATAGTCTATAGGAAAGCAGCCTCCAAACTGCA
GCTCACCAACATGATCATAGAAGGAGGCCATTTTACTCTGGGAGCCCAGAAACCCGCTGCCGATGCTGACCTCCAGTTGAGTGAGATACT
CAAATTTGGTTTGGATAAACTGCTGGCCTCTGAGGGGAGCACCATGGATGAAATAGACCTGGAGTCCATACTGGGAGAAACAAAAGATGG
CCAGTGGGTCTCTGATGCCTTGCCTGCAGCAGAAGGAGGGAGCAGAGATCAAGAGGAAGGAAAAAATCATATGTACTTATTTGAAGGTAA
AGATTATTCTAAAGAGCCCAGTAAGGAAGACAGAAAATCATTTGAACAACTGGTAAACCTTCAGAAAACCCTTTTGGAGAAAGCTAGTCA
AGAGGGCCGATCACTCCGAAATAAAGGCAGTGTTCTCATCCCAGGCCTTGTGGAGGGATCTACCAAAAGGAAGCGGGTTCTGAGTCCAGA
AGAGCTGGAGGACAGACAGAAGAAAAGACAAGAAGCAGCTGCCAAGAGAAGGAGACTCATAGAGGAGAAGAAGAGGCAAAAGGAAGAGGC
TGAACATAAGAAAAAGATGGCCTGGTGGGAATCCAACAATTACCAGTCCTTCTGCCTGCCCTCTGAGGAGAGCGAGCCAGAGGACCTTGA
GAATGGGGAAGAGAGCTCTGCTGAGCTGGATTACCAAGACCCAGATGCTACTTCCCTCAAGTACGTTAGTGGTGATGTCACCCACCCTCA
GGCTGGGGCCGAGGATGCTCTCATTGTGCACTGCGTAGATGACTCTGGCCACTGGGGCAGAGGTGGTTTATTTACAGCTCTGGAAAAGCG
ATCCGCTGAGCCAAGAAAAATATATGAGCTGGCTGGGAAAATGAAAGACCTGAGTTTGGGAGGTGTCCTTTTATTTCCTGTTGATGATAA
AGAATCAAGAAACAAAGGGCAAGATTTGTTGGCCTTGATTGTGGCTCAGCATCGTGATCGTTCCAATGTCCTGTCTGGCATTAAGATGGC
AGCCCTAGAAGAGGGCCTGAAGAAGATATTTTTAGCAGCAAAAAAGAAGAAAGCAAGTGTTCATCTTCCACGTATTGGACATGCCACGAA
AGGTTTTAACTGGTATGGTACTGAGCGACTTATTCGGAAACATCTGGCTGCAAGAGGCATCCCAACTTACATATATTATTTTCCTAGAAG
CAAGTCTGCTGTCCTTCATGCACAGTCTTCATCTTCCTCCTCAAGACAGCTGGTGCCTTAAGAATTGGCCCAGCCTCAGATCCTGTCTTT
AGCAACCAGCTAATATTTACCCAGAGGTACTGCAATAGAGTATTTCAAAATGGAATCAGGATCTGGTGGGCCTCAGAAATTGTCTCTTTT
CTGAGTTTCAATTTGGTTCTCCTGGATGTTTTGCTCTGTTTTGGTACCTGTAATATAGGGAAACACAACTTTTTTTGGGAAAGCCCTTTG

>71387_71387_5_RAB3IP-CHD1L_RAB3IP_chr12_70150443_ENST00000550536_CHD1L_chr1_146736080_ENST00000431239_length(amino acids)=801AA_BP=190
MPVVMGLKKMKGLSYDEAFAMANDPLEGFHEVNLASPTSPDLLGVYESGTQEQTTSPSVIYRPHPSALSSVPIQANALDVSELPTQPVYS
SPRRLNCAEISSISFHVTDPAPCSTSGVTAGLTKLTTRKDNYNAEREFLQGATITEACDGSDDIFGLSTDSLSRLRSPSVLEVREKGYER
LKEELAKAQRFSVVFSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELPK
KTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVKLQNILSQLRKCVDHPYLFDGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAH
RIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETK
DGQWVSDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQEGRSLRNKGSVLIPGLVEGSTKRKRVLS
PEELEDRQKKRQEAAAKRRRLIEEKKRQKEEAEHKKKMAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYVSGDVTH
PQAGAEDALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKDLSLGGVLLFPVDDKESRNKGQDLLALIVAQHRDRSNVLSGIK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RAB3IP-CHD1L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RAB3IP-CHD1L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RAB3IP-CHD1L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource