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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RAB4B-EXOC4 (FusionGDB2 ID:71432)

Fusion Gene Summary for RAB4B-EXOC4

check button Fusion gene summary
Fusion gene informationFusion gene name: RAB4B-EXOC4
Fusion gene ID: 71432
HgeneTgene
Gene symbol

RAB4B

EXOC4

Gene ID

100529262

60412

Gene nameMIA-RAB4B readthrough (NMD candidate)exocyst complex component 4
SynonymsRAB4BSEC8|SEC8L1|Sec8p
Cytomap

19q13.2

7q33

Type of genencRNAprotein-coding
DescriptionRas-related protein Rab-4Bexocyst complex component 4SEC8-like 1exocyst complex component Sec8
Modification date2020031320200320
UniProtAcc.

Q96A65

Ensembl transtripts involved in fusion geneENST00000602069, ENST00000357052, 
ENST00000594800, 		ENST00000253861, 
ENST00000393161, ENST00000539845, 
ENST00000460346, ENST00000541309, 
ENST00000545148, 
Fusion gene scores* DoF score3 X 2 X 3=1835 X 25 X 10=8750
# samples 339
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(39/8750*10)=-4.48773698785744
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RAB4B [Title/Abstract] AND EXOC4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEXOC4(133002144)-RAB4B(41285924), # samples:3
RAB4B(41284296)-EXOC4(133041084), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across RAB4B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EXOC4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-19-0957-02ARAB4Bchr19

41284296

-EXOC4chr7

133041084

+
ChimerDB4GBMTCGA-19-0957-02ARAB4Bchr19

41284296

+EXOC4chr7

133041084

+


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Fusion Gene ORF analysis for RAB4B-EXOC4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000602069ENST00000253861RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
3UTR-3CDSENST00000602069ENST00000393161RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
3UTR-3CDSENST00000602069ENST00000539845RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
3UTR-intronENST00000602069ENST00000460346RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
3UTR-intronENST00000602069ENST00000541309RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
3UTR-intronENST00000602069ENST00000545148RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
5CDS-intronENST00000357052ENST00000460346RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
5CDS-intronENST00000357052ENST00000541309RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
5CDS-intronENST00000357052ENST00000545148RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
5CDS-intronENST00000594800ENST00000460346RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
5CDS-intronENST00000594800ENST00000541309RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
5CDS-intronENST00000594800ENST00000545148RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
In-frameENST00000357052ENST00000253861RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
In-frameENST00000357052ENST00000393161RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
In-frameENST00000357052ENST00000539845RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
In-frameENST00000594800ENST00000253861RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
In-frameENST00000594800ENST00000393161RAB4Bchr19

41284296

+EXOC4chr7

133041084

+
In-frameENST00000594800ENST00000539845RAB4Bchr19

41284296

+EXOC4chr7

133041084

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000594800RAB4Bchr1941284296+ENST00000253861EXOC4chr7133041084+3569176942337747
ENST00000594800RAB4Bchr1941284296+ENST00000539845EXOC4chr7133041084+2397176942337747
ENST00000594800RAB4Bchr1941284296+ENST00000393161EXOC4chr7133041084+98817694834246
ENST00000357052RAB4Bchr1941284296+ENST00000253861EXOC4chr7133041084+3519126442287747
ENST00000357052RAB4Bchr1941284296+ENST00000539845EXOC4chr7133041084+2347126442287747
ENST00000357052RAB4Bchr1941284296+ENST00000393161EXOC4chr7133041084+93812644784246

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000594800ENST00000253861RAB4Bchr1941284296+EXOC4chr7133041084+0.0042036590.9957963
ENST00000594800ENST00000539845RAB4Bchr1941284296+EXOC4chr7133041084+0.0096979370.990302
ENST00000594800ENST00000393161RAB4Bchr1941284296+EXOC4chr7133041084+0.0022110610.9977889
ENST00000357052ENST00000253861RAB4Bchr1941284296+EXOC4chr7133041084+0.0042303080.99576974
ENST00000357052ENST00000539845RAB4Bchr1941284296+EXOC4chr7133041084+0.0095704480.9904295
ENST00000357052ENST00000393161RAB4Bchr1941284296+EXOC4chr7133041084+0.0024724190.99752754

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Fusion Genomic Features for RAB4B-EXOC4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RAB4Bchr1941284296+EXOC4chr7133041083+7.69E-091
RAB4Bchr1941284296+EXOC4chr7133041083+7.69E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for RAB4B-EXOC4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:133002144/chr7:41285924)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EXOC4

Q96A65

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRAB4Bchr19:41284296chr7:133041084ENST00000357052+1837_455296.3333333333333MotifEffector region
HgeneRAB4Bchr19:41284296chr7:133041084ENST00000594800+1837_455274.0MotifEffector region
HgeneRAB4Bchr19:41284296chr7:133041084ENST00000357052+18121_1245296.3333333333333Nucleotide bindingGTP
HgeneRAB4Bchr19:41284296chr7:133041084ENST00000357052+18151_1535296.3333333333333Nucleotide bindingGTP
HgeneRAB4Bchr19:41284296chr7:133041084ENST00000357052+1815_235296.3333333333333Nucleotide bindingGTP
HgeneRAB4Bchr19:41284296chr7:133041084ENST00000357052+1863_675296.3333333333333Nucleotide bindingGTP
HgeneRAB4Bchr19:41284296chr7:133041084ENST00000594800+18121_1245274.0Nucleotide bindingGTP
HgeneRAB4Bchr19:41284296chr7:133041084ENST00000594800+18151_1535274.0Nucleotide bindingGTP
HgeneRAB4Bchr19:41284296chr7:133041084ENST00000594800+1815_235274.0Nucleotide bindingGTP
HgeneRAB4Bchr19:41284296chr7:133041084ENST00000594800+1863_675274.0Nucleotide bindingGTP
TgeneEXOC4chr19:41284296chr7:133041084ENST0000025386141832_114254975.0Coiled coilOntology_term=ECO:0000255
TgeneEXOC4chr19:41284296chr7:133041084ENST0000039316141032_114254474.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for RAB4B-EXOC4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>71432_71432_1_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000357052_EXOC4_chr7_133041084_ENST00000253861_length(transcript)=3519nt_BP=126nt
CCGGGGAGTAGGAAGGAGCCGGGGCTGTAGCCGGAGTGGAGCGGCTGCCAGCCGAGGAGCAGGCGCGGCCGCGGCGCCATATTGCGGCCC
TCAGCGGCCGCGACCGAGTCATGGCTGAGACCTACGTGAGGGAGATAAATCTGCAGGACATCAAGGAAGATTTAGAATTGGATCCAGAGG
AAAACAGCACCCTGTTTATGGGTATCCTCATTAAGGGCTTGGCGAAACTGAAGAAGATCCCAGAAACAGTTAAGGCAATCATAGAGCGCT
TGGAGCAGGAGTTGAAGCAAATTGTGAAGAGGTCTACAACCCAGGTGGCAGACAGTGGCTATCAGCGGGGGGAGAACGTTACTGTGGAGA
ACCAACCAAGGTTGCTTCTAGAACTGCTGGAGTTACTGTTTGACAAGTTTAATGCTGTAGCCGCTGCACACTCTGTGGTCCTGGGATACC
TGCAGGACACTGTAGTGACTCCACTGACTCAGCAGGAAGATATCAAACTGTATGATATGGCAGATGTATGGGTGAAGATCCAAGATGTTC
TACAGATGCTATTAACTGAGTACTTGGATATGAAAAATACTCGTACGGCCTCTGAACCATCAGCTCAACTAAGCTATGCCAGCACTGGAC
GAGAGTTTGCAGCCTTTTTTGCCAAGAAGAAACCTCAAAGGCCAAAAAATTCTCTTTTCAAGTTCGAATCGTCCTCCCATGCCATCAGTA
TGAGCGCCTATCTGCGAGAACAGAGAAGGGAGCTCTATAGTCGGAGTGGAGAACTGCAAGGGGGTCCTGATGACAACTTAATTGAAGGTG
GAGGAACAAAATTTGTCTGCAAACCTGGAGCCAGAAACATTACCGTCATATTCCACCCATTACTAAGATTTATTCAGGAGATTGAGCATG
CTCTGGGTCTTGGCCCAGCCAAACAGTGTCCTCTTCGAGAGTTTCTCACCGTGTACATCAAAAACATCTTTCTCAATCAAGTCTTGGCTG
AGATCAACAAGGAGATTGAAGGAGTCACTAAAACATCTGACCCTTTGAAGATTCTGGCCAACGCAGACACCATGAAGGTGCTGGGAGTGC
AGCGGCCTCTCCTACAGAGCACAATCATTGTGGAGAAGACAGTTCAAGACCTCCTGAACCTGATGCATGACTTGAGTGCATATTCAGATC
AATTCCTCAACATGGTGTGCGTGAAGCTCCAGGAGTACAAGGACACCTGCACTGCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAAC
TTGTCATCAGTGCATCCTGGGCAAAAGATGATGATATCAGCAGACTCTTGAAATCTCTACCAAACTGGATGAATATGGCTCAACCCAAAC
AGCTGAGGCCAAAAAGAGAGGAGGAAGAAGATTTCATAAGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATA
AATTAATCCCTCCACAAGACATCCTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTC
GAACAAAGTCAGCTTTCTCCAATCTTTCTACATCCCAGATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGT
CAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGA
GGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCC
TGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAG
GCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGA
ACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTT
ACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGC
ACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCA
AGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAGCAGGGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTTTT
TCCTTGGTATGTTATTGAGTATATTCTGAGCTTAGTTTTCTCTACAGTGATACTTTAGTGGAGAGGAGGTGTAAGGATTCTTTCTCTCTG
GTTTTGGCTTTTCATATAAATGCTAAAGGAAGGCGACAGTACAGAGTGTTTTGGTTGAACAACTACTTTAATGCAGTCAAATCTAACGGG
ACTAGGGTGGGATAGGGAGGAAGGTGGTATCAAATTGTTGGACTCTGAAAAACAAGTGGATGGATTACTAATATTTGATTTATTACTCAA
TATATATATAATTCCAGCCTTGGAAAGTAGGAAAGTAGGCTGCTACCTAACTTTTAGTCCCTTCCAAAACCATTTAGTAGGGTTCTATTA
CATAAACAGTAGGGTTTTTCCTCTCCTGACCTTATCCGTTTACAGTTCAATGAAATAAGTGTATGTGCATTGCTGTCTGTCTCTATTGCC
AAAATCAAATAAATGGCTTCTCAGCTGCTGTTTACAACAAACTTCCCTAACCAAAACAGAACCTCTAATTTAGGGCTAGGAATAGAAGTC
TTTTGATCCCAGTCCCTGGGACAGTTTTGTATGCTGTATCTTGTACACAGGTTGTAGGTTGGTTTATTGCCATTTTGTTTTATTTCTGCT
GTATAAAAACCAAGAGCCAGACAATTAGACAACTATGGAGGAATGAAAGGCAATTCAAACATCTGCTTGATTCCCGCCCCGCCACCCCTA
ATTTCTGAGAGAATAATGGTTAGAGAACATTGCATCTCACTTGAAACATCCTTTGGGGGTAAATGATTCTTAGGTGCTCACTTGGTCTGA
GCTCAGCTGAATGCAGGGAAGATGGGACAGAGTGACATTTCTCCTCTGTGCGGCCTCCAGCTGAGCCTGTCTCTGAATTGTTCCCTCCCC
CGCAATGTGGGCACTTACCATGTTCCTGGCACACTGGACCTCACCATGTCCCCCGGTCACCAGTCCTCTTGCTGCCCATGGTTCATAGGT
CATAGAAGGCAGCAATGCACTGACTGGGCCACATCTTGAAAACTCGTGGAAAGGGAAAGGGGAGGAGATGGGACTTTGACCACACACAGT
GATGCCTCACACCCTGAAGGTGGGGGATTTTGTACCTGTTTGTACAACTTTGGTCTTGATGGGAAAAATGGAGAATTAAAAAGTGTTTTG

>71432_71432_1_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000357052_EXOC4_chr7_133041084_ENST00000253861_length(amino acids)=747AA_BP=27
MPAEEQARPRRHIAALSGRDRVMAETYVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQ
VADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTR
TASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPDDNLIEGGGTKFVCKPGARNIT
VIFHPLLRFIQEIEHALGLGPAKQCPLREFLTVYIKNIFLNQVLAEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTV
QDLLNLMHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQPKQLRPKREEEEDFIRA
AFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSF
QDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQ
YFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNT

--------------------------------------------------------------
>71432_71432_2_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000357052_EXOC4_chr7_133041084_ENST00000393161_length(transcript)=938nt_BP=126nt
CCGGGGAGTAGGAAGGAGCCGGGGCTGTAGCCGGAGTGGAGCGGCTGCCAGCCGAGGAGCAGGCGCGGCCGCGGCGCCATATTGCGGCCC
TCAGCGGCCGCGACCGAGTCATGGCTGAGACCTACGTGAGGGAGATAAATCTGCAGGACATCAAGGAAGATTTAGAATTGGATCCAGAGG
AAAACAGCACCCTGTTTATGGGTATCCTCATTAAGGGCTTGGCGAAACTGAAGAAGATCCCAGAAACAGTTAAGGCAATCATAGAGCGCT
TGGAGCAGGAGTTGAAGCAAATTGTGAAGAGGTCTACAACCCAGGTGGCAGACAGTGGCTATCAGCGGGGGGAGAACGTTACTGTGGAGA
ACCAACCAAGGTTGCTTCTAGAACTGCTGGAGTTACTGTTTGACAAGTTTAATGCTGTAGCCGCTGCACACTCTGTGGTCCTGGGATACC
TGCAGGACACTGTAGTGACTCCACTGACTCAGCAGGAAGATATCAAACTGTATGATATGGCAGATGTATGGGTGAAGATCCAAGATGTTC
TACAGATGCTATTAACTGAGTACTTGGATATGAAAAATACTCGTACGGCCTCTGAACCATCAGCTCAACTAAGCTATGCCAGCACTGGAC
GAGAGTTTGCAGCCTTTTTTGCCAAGAAGAAACCTCAAAGGCCAAAAAATTCTCTTTTCAAGTTCGAATCGTCCTCCCATGCCATCAGTA
TGAGCGCCTATCTGCGAGAACAGAGAAGGGAGCTCTATAGTCGGAGTGGAGAACTGCAAGGGTAGCGGCGAAGAAATCCACCAGAAAGAC
AATCAAAGTAACATTAAAAAGCTCAAATTTTACAAAAGTTAAGTTCCTGCCAACATTTTCAATTTATCATACAATTAGAAATGTGACTCA

>71432_71432_2_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000357052_EXOC4_chr7_133041084_ENST00000393161_length(amino acids)=246AA_BP=27
MPAEEQARPRRHIAALSGRDRVMAETYVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQ
VADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTR

--------------------------------------------------------------
>71432_71432_3_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000357052_EXOC4_chr7_133041084_ENST00000539845_length(transcript)=2347nt_BP=126nt
CCGGGGAGTAGGAAGGAGCCGGGGCTGTAGCCGGAGTGGAGCGGCTGCCAGCCGAGGAGCAGGCGCGGCCGCGGCGCCATATTGCGGCCC
TCAGCGGCCGCGACCGAGTCATGGCTGAGACCTACGTGAGGGAGATAAATCTGCAGGACATCAAGGAAGATTTAGAATTGGATCCAGAGG
AAAACAGCACCCTGTTTATGGGTATCCTCATTAAGGGCTTGGCGAAACTGAAGAAGATCCCAGAAACAGTTAAGGCAATCATAGAGCGCT
TGGAGCAGGAGTTGAAGCAAATTGTGAAGAGGTCTACAACCCAGGTGGCAGACAGTGGCTATCAGCGGGGGGAGAACGTTACTGTGGAGA
ACCAACCAAGGTTGCTTCTAGAACTGCTGGAGTTACTGTTTGACAAGTTTAATGCTGTAGCCGCTGCACACTCTGTGGTCCTGGGATACC
TGCAGGACACTGTAGTGACTCCACTGACTCAGCAGGAAGATATCAAACTGTATGATATGGCAGATGTATGGGTGAAGATCCAAGATGTTC
TACAGATGCTATTAACTGAGTACTTGGATATGAAAAATACTCGTACGGCCTCTGAACCATCAGCTCAACTAAGCTATGCCAGCACTGGAC
GAGAGTTTGCAGCCTTTTTTGCCAAGAAGAAACCTCAAAGGCCAAAAAATTCTCTTTTCAAGTTCGAATCGTCCTCCCATGCCATCAGTA
TGAGCGCCTATCTGCGAGAACAGAGAAGGGAGCTCTATAGTCGGAGTGGAGAACTGCAAGGGGGTCCTGATGACAACTTAATTGAAGGTG
GAGGAACAAAATTTGTCTGCAAACCTGGAGCCAGAAACATTACCGTCATATTCCACCCATTACTAAGATTTATTCAGGAGATTGAGCATG
CTCTGGGTCTTGGCCCAGCCAAACAGTGTCCTCTTCGAGAGTTTCTCACCGTGTACATCAAAAACATCTTTCTCAATCAAGTCTTGGCTG
AGATCAACAAGGAGATTGAAGGAGTCACTAAAACATCTGACCCTTTGAAGATTCTGGCCAACGCAGACACCATGAAGGTGCTGGGAGTGC
AGCGGCCTCTCCTACAGAGCACAATCATTGTGGAGAAGACAGTTCAAGACCTCCTGAACCTGATGCATGACTTGAGTGCATATTCAGATC
AATTCCTCAACATGGTGTGCGTGAAGCTCCAGGAGTACAAGGACACCTGCACTGCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAAC
TTGTCATCAGTGCATCCTGGGCAAAAGATGATGATATCAGCAGACTCTTGAAATCTCTACCAAACTGGATGAATATGGCTCAACCCAAAC
AGCTGAGGCCAAAAAGAGAGGAGGAAGAAGATTTCATAAGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATA
AATTAATCCCTCCACAAGACATCCTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTC
GAACAAAGTCAGCTTTCTCCAATCTTTCTACATCCCAGATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGT
CAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGA
GGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCC
TGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAG
GCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGA
ACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTT
ACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGC
ACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCA
AGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAGCAGGGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTTTT

>71432_71432_3_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000357052_EXOC4_chr7_133041084_ENST00000539845_length(amino acids)=747AA_BP=27
MPAEEQARPRRHIAALSGRDRVMAETYVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQ
VADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTR
TASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPDDNLIEGGGTKFVCKPGARNIT
VIFHPLLRFIQEIEHALGLGPAKQCPLREFLTVYIKNIFLNQVLAEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTV
QDLLNLMHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQPKQLRPKREEEEDFIRA
AFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSF
QDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQ
YFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNT

--------------------------------------------------------------
>71432_71432_4_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000594800_EXOC4_chr7_133041084_ENST00000253861_length(transcript)=3569nt_BP=176nt
GGAGCGGGTCGCGCCGGAGGGGGGCGGAGGCGGAAGTGGCGGTGCCGGGCCCGGGGAGTAGGAAGGAGCCGGGGCTGTAGCCGGAGTGGA
GCGGCTGCCAGCCGAGGAGCAGGCGCGGCCGCGGCGCCATATTGCGGCCCTCAGCGGCCGCGACCGAGTCATGGCTGAGACCTACGTGAG
GGAGATAAATCTGCAGGACATCAAGGAAGATTTAGAATTGGATCCAGAGGAAAACAGCACCCTGTTTATGGGTATCCTCATTAAGGGCTT
GGCGAAACTGAAGAAGATCCCAGAAACAGTTAAGGCAATCATAGAGCGCTTGGAGCAGGAGTTGAAGCAAATTGTGAAGAGGTCTACAAC
CCAGGTGGCAGACAGTGGCTATCAGCGGGGGGAGAACGTTACTGTGGAGAACCAACCAAGGTTGCTTCTAGAACTGCTGGAGTTACTGTT
TGACAAGTTTAATGCTGTAGCCGCTGCACACTCTGTGGTCCTGGGATACCTGCAGGACACTGTAGTGACTCCACTGACTCAGCAGGAAGA
TATCAAACTGTATGATATGGCAGATGTATGGGTGAAGATCCAAGATGTTCTACAGATGCTATTAACTGAGTACTTGGATATGAAAAATAC
TCGTACGGCCTCTGAACCATCAGCTCAACTAAGCTATGCCAGCACTGGACGAGAGTTTGCAGCCTTTTTTGCCAAGAAGAAACCTCAAAG
GCCAAAAAATTCTCTTTTCAAGTTCGAATCGTCCTCCCATGCCATCAGTATGAGCGCCTATCTGCGAGAACAGAGAAGGGAGCTCTATAG
TCGGAGTGGAGAACTGCAAGGGGGTCCTGATGACAACTTAATTGAAGGTGGAGGAACAAAATTTGTCTGCAAACCTGGAGCCAGAAACAT
TACCGTCATATTCCACCCATTACTAAGATTTATTCAGGAGATTGAGCATGCTCTGGGTCTTGGCCCAGCCAAACAGTGTCCTCTTCGAGA
GTTTCTCACCGTGTACATCAAAAACATCTTTCTCAATCAAGTCTTGGCTGAGATCAACAAGGAGATTGAAGGAGTCACTAAAACATCTGA
CCCTTTGAAGATTCTGGCCAACGCAGACACCATGAAGGTGCTGGGAGTGCAGCGGCCTCTCCTACAGAGCACAATCATTGTGGAGAAGAC
AGTTCAAGACCTCCTGAACCTGATGCATGACTTGAGTGCATATTCAGATCAATTCCTCAACATGGTGTGCGTGAAGCTCCAGGAGTACAA
GGACACCTGCACTGCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGTGCATCCTGGGCAAAAGATGATGATATCAG
CAGACTCTTGAAATCTCTACCAAACTGGATGAATATGGCTCAACCCAAACAGCTGAGGCCAAAAAGAGAGGAGGAAGAAGATTTCATAAG
GGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGACATCCTTCGTGACGTCAGTGA
CCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTCCAATCTTTCTACATCCCAGAT
GCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATC
GTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGA
GGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGA
GGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGC
CCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCAT
GTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCA
GGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAA
CACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAGCA
GGGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTTTTTCCTTGGTATGTTATTGAGTATATTCTGAGCTTAGTTTTC
TCTACAGTGATACTTTAGTGGAGAGGAGGTGTAAGGATTCTTTCTCTCTGGTTTTGGCTTTTCATATAAATGCTAAAGGAAGGCGACAGT
ACAGAGTGTTTTGGTTGAACAACTACTTTAATGCAGTCAAATCTAACGGGACTAGGGTGGGATAGGGAGGAAGGTGGTATCAAATTGTTG
GACTCTGAAAAACAAGTGGATGGATTACTAATATTTGATTTATTACTCAATATATATATAATTCCAGCCTTGGAAAGTAGGAAAGTAGGC
TGCTACCTAACTTTTAGTCCCTTCCAAAACCATTTAGTAGGGTTCTATTACATAAACAGTAGGGTTTTTCCTCTCCTGACCTTATCCGTT
TACAGTTCAATGAAATAAGTGTATGTGCATTGCTGTCTGTCTCTATTGCCAAAATCAAATAAATGGCTTCTCAGCTGCTGTTTACAACAA
ACTTCCCTAACCAAAACAGAACCTCTAATTTAGGGCTAGGAATAGAAGTCTTTTGATCCCAGTCCCTGGGACAGTTTTGTATGCTGTATC
TTGTACACAGGTTGTAGGTTGGTTTATTGCCATTTTGTTTTATTTCTGCTGTATAAAAACCAAGAGCCAGACAATTAGACAACTATGGAG
GAATGAAAGGCAATTCAAACATCTGCTTGATTCCCGCCCCGCCACCCCTAATTTCTGAGAGAATAATGGTTAGAGAACATTGCATCTCAC
TTGAAACATCCTTTGGGGGTAAATGATTCTTAGGTGCTCACTTGGTCTGAGCTCAGCTGAATGCAGGGAAGATGGGACAGAGTGACATTT
CTCCTCTGTGCGGCCTCCAGCTGAGCCTGTCTCTGAATTGTTCCCTCCCCCGCAATGTGGGCACTTACCATGTTCCTGGCACACTGGACC
TCACCATGTCCCCCGGTCACCAGTCCTCTTGCTGCCCATGGTTCATAGGTCATAGAAGGCAGCAATGCACTGACTGGGCCACATCTTGAA
AACTCGTGGAAAGGGAAAGGGGAGGAGATGGGACTTTGACCACACACAGTGATGCCTCACACCCTGAAGGTGGGGGATTTTGTACCTGTT

>71432_71432_4_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000594800_EXOC4_chr7_133041084_ENST00000253861_length(amino acids)=747AA_BP=27
MPAEEQARPRRHIAALSGRDRVMAETYVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQ
VADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTR
TASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPDDNLIEGGGTKFVCKPGARNIT
VIFHPLLRFIQEIEHALGLGPAKQCPLREFLTVYIKNIFLNQVLAEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTV
QDLLNLMHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQPKQLRPKREEEEDFIRA
AFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSF
QDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQ
YFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNT

--------------------------------------------------------------
>71432_71432_5_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000594800_EXOC4_chr7_133041084_ENST00000393161_length(transcript)=988nt_BP=176nt
GGAGCGGGTCGCGCCGGAGGGGGGCGGAGGCGGAAGTGGCGGTGCCGGGCCCGGGGAGTAGGAAGGAGCCGGGGCTGTAGCCGGAGTGGA
GCGGCTGCCAGCCGAGGAGCAGGCGCGGCCGCGGCGCCATATTGCGGCCCTCAGCGGCCGCGACCGAGTCATGGCTGAGACCTACGTGAG
GGAGATAAATCTGCAGGACATCAAGGAAGATTTAGAATTGGATCCAGAGGAAAACAGCACCCTGTTTATGGGTATCCTCATTAAGGGCTT
GGCGAAACTGAAGAAGATCCCAGAAACAGTTAAGGCAATCATAGAGCGCTTGGAGCAGGAGTTGAAGCAAATTGTGAAGAGGTCTACAAC
CCAGGTGGCAGACAGTGGCTATCAGCGGGGGGAGAACGTTACTGTGGAGAACCAACCAAGGTTGCTTCTAGAACTGCTGGAGTTACTGTT
TGACAAGTTTAATGCTGTAGCCGCTGCACACTCTGTGGTCCTGGGATACCTGCAGGACACTGTAGTGACTCCACTGACTCAGCAGGAAGA
TATCAAACTGTATGATATGGCAGATGTATGGGTGAAGATCCAAGATGTTCTACAGATGCTATTAACTGAGTACTTGGATATGAAAAATAC
TCGTACGGCCTCTGAACCATCAGCTCAACTAAGCTATGCCAGCACTGGACGAGAGTTTGCAGCCTTTTTTGCCAAGAAGAAACCTCAAAG
GCCAAAAAATTCTCTTTTCAAGTTCGAATCGTCCTCCCATGCCATCAGTATGAGCGCCTATCTGCGAGAACAGAGAAGGGAGCTCTATAG
TCGGAGTGGAGAACTGCAAGGGTAGCGGCGAAGAAATCCACCAGAAAGACAATCAAAGTAACATTAAAAAGCTCAAATTTTACAAAAGTT

>71432_71432_5_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000594800_EXOC4_chr7_133041084_ENST00000393161_length(amino acids)=246AA_BP=27
MPAEEQARPRRHIAALSGRDRVMAETYVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQ
VADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTR

--------------------------------------------------------------
>71432_71432_6_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000594800_EXOC4_chr7_133041084_ENST00000539845_length(transcript)=2397nt_BP=176nt
GGAGCGGGTCGCGCCGGAGGGGGGCGGAGGCGGAAGTGGCGGTGCCGGGCCCGGGGAGTAGGAAGGAGCCGGGGCTGTAGCCGGAGTGGA
GCGGCTGCCAGCCGAGGAGCAGGCGCGGCCGCGGCGCCATATTGCGGCCCTCAGCGGCCGCGACCGAGTCATGGCTGAGACCTACGTGAG
GGAGATAAATCTGCAGGACATCAAGGAAGATTTAGAATTGGATCCAGAGGAAAACAGCACCCTGTTTATGGGTATCCTCATTAAGGGCTT
GGCGAAACTGAAGAAGATCCCAGAAACAGTTAAGGCAATCATAGAGCGCTTGGAGCAGGAGTTGAAGCAAATTGTGAAGAGGTCTACAAC
CCAGGTGGCAGACAGTGGCTATCAGCGGGGGGAGAACGTTACTGTGGAGAACCAACCAAGGTTGCTTCTAGAACTGCTGGAGTTACTGTT
TGACAAGTTTAATGCTGTAGCCGCTGCACACTCTGTGGTCCTGGGATACCTGCAGGACACTGTAGTGACTCCACTGACTCAGCAGGAAGA
TATCAAACTGTATGATATGGCAGATGTATGGGTGAAGATCCAAGATGTTCTACAGATGCTATTAACTGAGTACTTGGATATGAAAAATAC
TCGTACGGCCTCTGAACCATCAGCTCAACTAAGCTATGCCAGCACTGGACGAGAGTTTGCAGCCTTTTTTGCCAAGAAGAAACCTCAAAG
GCCAAAAAATTCTCTTTTCAAGTTCGAATCGTCCTCCCATGCCATCAGTATGAGCGCCTATCTGCGAGAACAGAGAAGGGAGCTCTATAG
TCGGAGTGGAGAACTGCAAGGGGGTCCTGATGACAACTTAATTGAAGGTGGAGGAACAAAATTTGTCTGCAAACCTGGAGCCAGAAACAT
TACCGTCATATTCCACCCATTACTAAGATTTATTCAGGAGATTGAGCATGCTCTGGGTCTTGGCCCAGCCAAACAGTGTCCTCTTCGAGA
GTTTCTCACCGTGTACATCAAAAACATCTTTCTCAATCAAGTCTTGGCTGAGATCAACAAGGAGATTGAAGGAGTCACTAAAACATCTGA
CCCTTTGAAGATTCTGGCCAACGCAGACACCATGAAGGTGCTGGGAGTGCAGCGGCCTCTCCTACAGAGCACAATCATTGTGGAGAAGAC
AGTTCAAGACCTCCTGAACCTGATGCATGACTTGAGTGCATATTCAGATCAATTCCTCAACATGGTGTGCGTGAAGCTCCAGGAGTACAA
GGACACCTGCACTGCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGTGCATCCTGGGCAAAAGATGATGATATCAG
CAGACTCTTGAAATCTCTACCAAACTGGATGAATATGGCTCAACCCAAACAGCTGAGGCCAAAAAGAGAGGAGGAAGAAGATTTCATAAG
GGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGACATCCTTCGTGACGTCAGTGA
CCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTCCAATCTTTCTACATCCCAGAT
GCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATC
GTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGA
GGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGA
GGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGC
CCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCAT
GTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCA
GGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAA
CACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAGCA

>71432_71432_6_RAB4B-EXOC4_RAB4B_chr19_41284296_ENST00000594800_EXOC4_chr7_133041084_ENST00000539845_length(amino acids)=747AA_BP=27
MPAEEQARPRRHIAALSGRDRVMAETYVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQ
VADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTR
TASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPDDNLIEGGGTKFVCKPGARNIT
VIFHPLLRFIQEIEHALGLGPAKQCPLREFLTVYIKNIFLNQVLAEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTV
QDLLNLMHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQPKQLRPKREEEEDFIRA
AFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSF
QDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQ
YFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RAB4B-EXOC4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RAB4B-EXOC4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RAB4B-EXOC4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource