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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ASMTL-CLEC7A (FusionGDB2 ID:7168)

Fusion Gene Summary for ASMTL-CLEC7A

check button Fusion gene summary
Fusion gene informationFusion gene name: ASMTL-CLEC7A
Fusion gene ID: 7168
HgeneTgene
Gene symbol

ASMTL

CLEC7A

Gene ID

8623

64581

Gene nameacetylserotonin O-methyltransferase likeC-type lectin domain containing 7A
SynonymsASMTLX|ASMTLY|ASTMLBGR|CANDF4|CD369|CLECSF12|DECTIN1|SCARE2
Cytomap

Xp22.33 and Yp11.2

12p13.2

Type of geneprotein-codingprotein-coding
Descriptionprobable bifunctional dTTP/UTP pyrophosphatase/methyltransferase proteinN-acetylserotonin O-methyltransferase-like proteinacetylserotonin N-methyltransferase-likeC-type lectin domain family 7 member AC-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12C-type lectin superfamily member 12DC-associated C-type lectin 1beta-glucan receptordectin-1dendritic cell-associated C-ty
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000381317, ENST00000381333, 
ENST00000416733, ENST00000534940, 
ENST00000463763, 		ENST00000310002, 
ENST00000525605, ENST00000298523, 
ENST00000304084, ENST00000396484, 
ENST00000533022, ENST00000353231, 
Fusion gene scores* DoF score15 X 11 X 4=6601 X 1 X 1=1
# samples 102
** MAII scorelog2(10/660*10)=-2.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/1*10)=4.32192809488736
Context

PubMed: ASMTL [Title/Abstract] AND CLEC7A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointASMTL(1540550)-CLEC7A(10271189), # samples:1
ASMTL(1540551)-CLEC7A(10271189), # samples:1
ASMTL(1490551)-CLEC7A(10271189), # samples:1
Anticipated loss of major functional domain due to fusion event.ASMTL-CLEC7A seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCLEC7A

GO:0006910

phagocytosis, recognition

11567029

TgeneCLEC7A

GO:0008037

cell recognition

11567029

TgeneCLEC7A

GO:0010628

positive regulation of gene expression

19358895

TgeneCLEC7A

GO:0016046

detection of fungus

19358895

TgeneCLEC7A

GO:0032491

detection of molecule of fungal origin

19358895

TgeneCLEC7A

GO:0032731

positive regulation of interleukin-1 beta production

22267217

TgeneCLEC7A

GO:0032930

positive regulation of superoxide anion generation

19358895

TgeneCLEC7A

GO:0042535

positive regulation of tumor necrosis factor biosynthetic process

19358895

TgeneCLEC7A

GO:0045078

positive regulation of interferon-gamma biosynthetic process

19358895

TgeneCLEC7A

GO:0045082

positive regulation of interleukin-10 biosynthetic process

19358895

TgeneCLEC7A

GO:0045084

positive regulation of interleukin-12 biosynthetic process

19358895

TgeneCLEC7A

GO:0045086

positive regulation of interleukin-2 biosynthetic process

19358895

TgeneCLEC7A

GO:0045410

positive regulation of interleukin-6 biosynthetic process

19358895

TgeneCLEC7A

GO:0045429

positive regulation of nitric oxide biosynthetic process

19358895

TgeneCLEC7A

GO:0050766

positive regulation of phagocytosis

19358895

TgeneCLEC7A

GO:0051251

positive regulation of lymphocyte activation

19358895

TgeneCLEC7A

GO:0051712

positive regulation of killing of cells of other organism

19358895

TgeneCLEC7A

GO:0060267

positive regulation of respiratory burst

19358895

TgeneCLEC7A

GO:0071226

cellular response to molecule of fungal origin

22267217

TgeneCLEC7A

GO:1900017

positive regulation of cytokine production involved in inflammatory response

22267217

TgeneCLEC7A

GO:1903431

positive regulation of cell maturation

19358895


check buttonFusion gene breakpoints across ASMTL (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CLEC7A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-13-0908-01BASMTLchrX

1540551

-CLEC7Achr12

10271189

-
ChimerDB4OVTCGA-13-0908-01BASMTLchrY

1490551

-CLEC7Achr12

10271189

-
ChimerDB4OVTCGA-13-0908ASMTLchrX

1540550

-CLEC7Achr12

10271189

-


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Fusion Gene ORF analysis for ASMTL-CLEC7A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000381317ENST00000310002ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
5CDS-intronENST00000381317ENST00000525605ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
5CDS-intronENST00000381333ENST00000310002ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
5CDS-intronENST00000381333ENST00000525605ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
5CDS-intronENST00000416733ENST00000310002ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
5CDS-intronENST00000416733ENST00000525605ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
5CDS-intronENST00000534940ENST00000310002ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
5CDS-intronENST00000534940ENST00000525605ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000381317ENST00000298523ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000381317ENST00000304084ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000381317ENST00000396484ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000381317ENST00000533022ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000381333ENST00000298523ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000381333ENST00000304084ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000381333ENST00000396484ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000381333ENST00000533022ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000416733ENST00000298523ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000416733ENST00000353231ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000416733ENST00000396484ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000534940ENST00000298523ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000534940ENST00000353231ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
Frame-shiftENST00000534940ENST00000396484ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
In-frameENST00000381317ENST00000353231ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
In-frameENST00000381333ENST00000353231ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
In-frameENST00000416733ENST00000304084ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
In-frameENST00000416733ENST00000533022ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
In-frameENST00000534940ENST00000304084ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
In-frameENST00000534940ENST00000533022ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381317ENST00000298523ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381317ENST00000298523ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381317ENST00000304084ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381317ENST00000304084ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381317ENST00000353231ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381317ENST00000353231ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381317ENST00000396484ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381317ENST00000396484ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381317ENST00000533022ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381317ENST00000533022ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381333ENST00000298523ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381333ENST00000298523ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381333ENST00000304084ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381333ENST00000304084ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381333ENST00000353231ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381333ENST00000353231ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381333ENST00000396484ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381333ENST00000396484ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381333ENST00000533022ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000381333ENST00000533022ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000416733ENST00000298523ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000416733ENST00000298523ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000416733ENST00000304084ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000416733ENST00000304084ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000416733ENST00000353231ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000416733ENST00000353231ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000416733ENST00000396484ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000416733ENST00000396484ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000416733ENST00000533022ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000416733ENST00000533022ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000298523ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000298523ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000298523ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000304084ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000304084ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000304084ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000353231ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000353231ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000353231ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000396484ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000396484ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000396484ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000533022ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000533022ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000463763ENST00000533022ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000534940ENST00000298523ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000534940ENST00000298523ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000534940ENST00000304084ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000534940ENST00000304084ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000534940ENST00000353231ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000534940ENST00000353231ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000534940ENST00000396484ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000534940ENST00000396484ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-3CDSENST00000534940ENST00000533022ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-3CDSENST00000534940ENST00000533022ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-intronENST00000381317ENST00000310002ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-intronENST00000381317ENST00000310002ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-intronENST00000381317ENST00000525605ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-intronENST00000381317ENST00000525605ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-intronENST00000381333ENST00000310002ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-intronENST00000381333ENST00000310002ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-intronENST00000381333ENST00000525605ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-intronENST00000381333ENST00000525605ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-intronENST00000416733ENST00000310002ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-intronENST00000416733ENST00000310002ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-intronENST00000416733ENST00000525605ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-intronENST00000416733ENST00000525605ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-intronENST00000463763ENST00000310002ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-intronENST00000463763ENST00000310002ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
intron-intronENST00000463763ENST00000310002ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-intronENST00000463763ENST00000525605ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-intronENST00000463763ENST00000525605ASMTLchrY

1490551

-CLEC7Achr12

10271189

-
intron-intronENST00000463763ENST00000525605ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-intronENST00000534940ENST00000310002ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-intronENST00000534940ENST00000310002ASMTLchrX

1540550

-CLEC7Achr12

10271189

-
intron-intronENST00000534940ENST00000525605ASMTLchrX

1540551

-CLEC7Achr12

10271189

-
intron-intronENST00000534940ENST00000525605ASMTLchrX

1540550

-CLEC7Achr12

10271189

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000416733ASMTLchrY1490551-ENST00000304084CLEC7Achr1210271189-15791215541292412
ENST00000416733ASMTLchrY1490551-ENST00000533022CLEC7Achr1210271189-13481215541292412
ENST00000534940ASMTLchrY1490551-ENST00000304084CLEC7Achr1210271189-166112971871374395
ENST00000534940ASMTLchrY1490551-ENST00000533022CLEC7Achr1210271189-143012971871374395
ENST00000381317ASMTLchrY1490551-ENST00000353231CLEC7Achr1210271189-30921278331355440
ENST00000381333ASMTLchrY1490551-ENST00000353231CLEC7Achr1210271189-3100128681363451

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000416733ENST00000304084ASMTLchrY1490551-CLEC7Achr1210271189-0.0075652340.99243474
ENST00000416733ENST00000533022ASMTLchrY1490551-CLEC7Achr1210271189-0.0109991790.9890008
ENST00000534940ENST00000304084ASMTLchrY1490551-CLEC7Achr1210271189-0.0047840440.995216
ENST00000534940ENST00000533022ASMTLchrY1490551-CLEC7Achr1210271189-0.0058957230.9941043
ENST00000381317ENST00000353231ASMTLchrY1490551-CLEC7Achr1210271189-0.0007801210.9992199
ENST00000381333ENST00000353231ASMTLchrY1490551-CLEC7Achr1210271189-0.0011238580.99887615

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Fusion Genomic Features for ASMTL-CLEC7A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ASMTL-CLEC7A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrY:1540550/chr12:10271189)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneASMTLchrY:1490551chr12:10271189ENST00000381317-91311_223415622.0RegionNote=MAF-like
HgeneASMTLchrY:1490551chr12:10271189ENST00000381333-81211_223399606.0RegionNote=MAF-like
HgeneASMTLchrY:1490551chr12:10271189ENST00000534940-91311_223357564.0RegionNote=MAF-like
TgeneCLEC7AchrY:1490551chr12:10271189ENST0000029852324127_242118144.0DomainC-type lectin
TgeneCLEC7AchrY:1490551chr12:10271189ENST0000031000203127_242078.0DomainC-type lectin
TgeneCLEC7AchrY:1490551chr12:10271189ENST0000039648424127_242124169.0DomainC-type lectin
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003100020315_18078.0MotifNote=ITAM-like
TgeneCLEC7AchrY:1490551chr12:10271189ENST00000310002031_44078.0Topological domainCytoplasmic
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003100020366_247078.0Topological domainExtracellular
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003100020345_65078.0TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneASMTLchrY:1490551chr12:10271189ENST00000381317-913277_621415622.0RegionNote=ASMT-like
HgeneASMTLchrY:1490551chr12:10271189ENST00000381317-913508_510415622.0RegionS-adenosyl-L-methionine binding
HgeneASMTLchrY:1490551chr12:10271189ENST00000381333-812277_621399606.0RegionNote=ASMT-like
HgeneASMTLchrY:1490551chr12:10271189ENST00000381333-812508_510399606.0RegionS-adenosyl-L-methionine binding
HgeneASMTLchrY:1490551chr12:10271189ENST00000534940-913277_621357564.0RegionNote=ASMT-like
HgeneASMTLchrY:1490551chr12:10271189ENST00000534940-913508_510357564.0RegionS-adenosyl-L-methionine binding
TgeneCLEC7AchrY:1490551chr12:10271189ENST0000030408446127_242203248.0DomainC-type lectin
TgeneCLEC7AchrY:1490551chr12:10271189ENST0000035323135127_242157202.0DomainC-type lectin
TgeneCLEC7AchrY:1490551chr12:10271189ENST0000053302235127_242164190.0DomainC-type lectin
TgeneCLEC7AchrY:1490551chr12:10271189ENST000002985232415_18118144.0MotifNote=ITAM-like
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003040844615_18203248.0MotifNote=ITAM-like
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003532313515_18157202.0MotifNote=ITAM-like
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003964842415_18124169.0MotifNote=ITAM-like
TgeneCLEC7AchrY:1490551chr12:10271189ENST000005330223515_18164190.0MotifNote=ITAM-like
TgeneCLEC7AchrY:1490551chr12:10271189ENST00000298523241_44118144.0Topological domainCytoplasmic
TgeneCLEC7AchrY:1490551chr12:10271189ENST000002985232466_247118144.0Topological domainExtracellular
TgeneCLEC7AchrY:1490551chr12:10271189ENST00000304084461_44203248.0Topological domainCytoplasmic
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003040844666_247203248.0Topological domainExtracellular
TgeneCLEC7AchrY:1490551chr12:10271189ENST00000353231351_44157202.0Topological domainCytoplasmic
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003532313566_247157202.0Topological domainExtracellular
TgeneCLEC7AchrY:1490551chr12:10271189ENST00000396484241_44124169.0Topological domainCytoplasmic
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003964842466_247124169.0Topological domainExtracellular
TgeneCLEC7AchrY:1490551chr12:10271189ENST00000533022351_44164190.0Topological domainCytoplasmic
TgeneCLEC7AchrY:1490551chr12:10271189ENST000005330223566_247164190.0Topological domainExtracellular
TgeneCLEC7AchrY:1490551chr12:10271189ENST000002985232445_65118144.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003040844645_65203248.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003532313545_65157202.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneCLEC7AchrY:1490551chr12:10271189ENST000003964842445_65124169.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneCLEC7AchrY:1490551chr12:10271189ENST000005330223545_65164190.0TransmembraneHelical%3B Signal-anchor for type II membrane protein


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Fusion Gene Sequence for ASMTL-CLEC7A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>7168_7168_1_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000381317_CLEC7A_chr12_10271189_ENST00000353231_length(transcript)=3092nt_BP=1278nt
AAGTGCGGACGCCCGGCTCCCGGCGTGGACGCCATGGTGCTGTGCCCGGTGATTGGGAAGCTGCTGCACAAGCGCGTGGTGCTGGCCAGC
GCCTCCCCACGCCGTCAGGAGATCCTCAGCAACGCGGGTCTCAGGTTTGAGGTGGTCCCCTCCAAGTTTAAAGAGAAGCTGGACAAAGCC
TCCTTCGCTACTCCGTATGGGTACGCCATGGAGACCGCCAAGCAGAAGGCCCTGGAGGTGGCCAACCGGCTGTACCAGAAAGACCTGCGG
GCCCCCGACGTGGTCATTGGAGCGGACACGATCGTGACAGTCGGGGGGCTGATTCTGGAGAAGCCGGTGGACAAGCAGGACGCCTACAGG
ATGCTGTCCCGGTTGAGTGGGAGAGAACACAGCGTGTTCACAGGTGTCGCGATCGTCCACTGCTCCAGCAAAGACCATCAGCTGGACACC
AGGGTCTCGGAATTCTACGAGGAAACGAAGGTGAAGTTCTCGGAGCTGTCCGAGGAGCTGCTCTGGGAATACGTCCACAGCGGGGAGCCC
ATGGACAAAGCTGGCGGCTACGGGATCCAGGCCCTGGGCGGCATGCTGGTGGAGTCCGTACACGGGGACTTTCTGAACGTGGTGGGATTC
CCGCTGAACCACTTCTGCAAGCAGCTGGTGAAGCTCTACTACCCGCCCCGTCCGGAGGACCTGCGGCGGAGTGTCAAGCACGACTCCATC
CCGGCCGCGGACACCTTCGAAGACCTCAGTGACGTGGAGGGGGGCGGCTCGGAGCCCACTCAGAGGGACGCGGGCAGCCGCGATGAGAAG
GCCGAGGCGGGAGAGGCGGGACAGGCCACGGCAGAGGCTGAGTGTCACAGGACTCGGGAGACCCTGCCTCCGTTCCCGACACGCCTCCTG
GAGCTGATTGAGGGCTTTATGCTATCCAAGGGCCTGCTCACCGCTTGCAAACTGAAGGTGTTCGATTTGTTAAAAGATGAAGCACCCCAG
AAGGCTGCGGATATTGCCAGCAAAGTGGACGCCTCTGCGTGTGGAATGGAGAGGCTTCTGGACATCTGTGCTGCCATGGGGCTCCTGGAG
AAGACAGAGCAAGGTTACAGTAACACAGAGACAGCGAACGTCTACCTGGCATCGGATGGCGAATACTCTCTGCACGGCTTCATCATGCAC
AATAATGACCTCACATGGAACCTCTTTACATACCTGGAGTTTGCCATCCGAGAGGGAACAAACCAGCACCACAGGGCGTTGGGGAAGAAG
GCGGAAGATCTGTTCCAGATTTCAGATCAGAACCACAGCTACCCAAGAAAACCCATCTCCAAATTGTGTATGGATTCACGTGTCAGTCAT
TTATGACCAACTGTGTAGTGTGCCCTCATATAGTATTTGTGAGAAGAAGTTTTCAATGTAAGAGGAAGGGTGGAGAAGGAGAGAGAAATA
TGTGAGGTAGTAAGGAGGACAGAAAACAGAACAGAAAAGAGTAACAGCTGAGGTCAAGATAAATGCAGAAAATGTTTAGAGAGCTTGGCC
AACTGTAATCTTAACCAAGAAATTGAAGGGAGAGGCTGTGATTTCTGTATTTGTCGACCTACAGGTAGGCTAGTATTATTTTTCTAGTTA
GTAGATCCCTAGACATGGAATCAGGGCAGCCAAGCTTGAGTTTTTATTTTTTATTTATTTATTTTTTTGAGATAGGGTCTCACTTTGTTA
CCCAGGCTGGAGTGCAGTGGCACAATCTCGACTCACTGCAGCTATCTCTCGCCTCAGCCCCTCAAGTAGCTGGGACTACAGGTGCATGCC
ACCATGCCAGGCTAATTTTTGGTGTTTTTTGTAGAGACTGGGTTTTGCCATGTTGACCAAGCTGGTCTCTAACTCCTGGGCTTAAGTGAT
CTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCCACCACACCTGGCCCCAAGCTTGAATTTTCATTCTGCCATTGACT
TGGCATTTACCTTGGGTAAGCCATAAGCGAATCTTAATTTCTGGCTCTATCAGAGTTGTTTCATGCTCAACAATGCCATTGAAGTGCACG
GTGTGTTGCCACGATTTGACCCTCAACTTCTAGCAGTATATCAGTTATGAACTGAGGGTGAAATATATTTCTGAATAGCTAAATGAAGAA
ATGGGAAAAAATCTTCACCACAGTCAGAGCAATTTTATTATTTTCATCAGTATGATCATAATTATGATTATCATCTTAGTAAAAAGCAGG
AACTCCTACTTTTTCTTTATCAATTAAATAGCTCAGAGAGTACATCTGCCATATCTCTAATAGAATCTTTTTTTTTTTTTTTTTTTTTGA
GACAGAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAACGGCACGATCTCGGCTCACCGCAACCTCCGCCCCCTGGGTTCAAGCAATTCT
CCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGTCAGGCACCACCACACCCGGCTAATTTTGTATTTTTTTAGTAGAGACAGGGTTTCT
CCATGTCGGTCAGGGTAGTCCCGAACTCCTGACCTCAAGTGATCTGCCTGCCTCGGCCTCCCAAGTGCTGGGATTACAGGCGTGAGCCAC
TGCACCCAGCCTAGAATCTTGTATAATATGTAATTGTAGGGAAACTGCTCTCATAGGAAAGTTTTCTGCTTTTTAAATACAAAAATACAT
AAAAATACATAAAATCTGATGATGAATATAAAAAAGTAACCAACCTCATTGGAACAAGTATTAACATTTTGGAATATGTTTTATTAGTTT
TGTGATGTACTGTTTTACAATTTTTACCATTTTTTTCAGTAATTACTGTAAAATGGTATTATTGGAATGAAACTATATTTCCTCATGTGC
TGATTTGTCTTATTTTTTTCATACTTTCCCACTGGTGCTATTTTTATTTCCAATGGATATTTCTGTATTACTAGGGAGGCATTTACAGTC
CTCTAATGTTGATTAATATGTGAAAAGAAATTGTACCAATTTTACTAAATTATGCAGTTTAAAATGGATGATTTTATGTTATGTGGATTT

>7168_7168_1_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000381317_CLEC7A_chr12_10271189_ENST00000353231_length(amino acids)=440AA_BP=414
MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAMETAKQKALEVANRLYQKDLRAPDVVIGADTI
VTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQA
LGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATA
EAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTET

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>7168_7168_2_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000381333_CLEC7A_chr12_10271189_ENST00000353231_length(transcript)=3100nt_BP=1286nt
CTGGCCGCCTGTTTTTTTTGCAGCCGCGCTGCGCGCACCGCGGGCTCCGGGCTCAGAAGTGCGGACGCCCGGCTCCCGGCGTGGACGCCA
TGGTGCTGTGCCCGGTGATTGGGAAGCTGCTGCACAAGCGCGTGGTGCTGGCCAGCGCCTCCCCACGCCGTCAGGAGATCCTCAGCAACG
CGGGTCTCAGGTTTGAGGTGGTCCCCTCCAAGTTTAAAGAGAAGCTGGACAAAGCCTCCTTCGCTACTCCGTATGGGTACGCCATGGAGA
CCGCCAAGCAGAAGGCCCTGGAGGTGGCCAACCGGCTGTACCAGACAGTCGGGGGGCTGATTCTGGAGAAGCCGGTGGACAAGCAGGACG
CCTACAGGATGCTGTCCCGGTTGAGTGGGAGAGAACACAGCGTGTTCACAGGTGTCGCGATCGTCCACTGCTCCAGCAAAGACCATCAGC
TGGACACCAGGGTCTCGGAATTCTACGAGGAAACGAAGGTGAAGTTCTCGGAGCTGTCCGAGGAGCTGCTCTGGGAATACGTCCACAGCG
GGGAGCCCATGGACAAAGCTGGCGGCTACGGGATCCAGGCCCTGGGCGGCATGCTGGTGGAGTCCGTACACGGGGACTTTCTGAACGTGG
TGGGATTCCCGCTGAACCACTTCTGCAAGCAGCTGGTGAAGCTCTACTACCCGCCCCGTCCGGAGGACCTGCGGCGGAGTGTCAAGCACG
ACTCCATCCCGGCCGCGGACACCTTCGAAGACCTCAGTGACGTGGAGGGGGGCGGCTCGGAGCCCACTCAGAGGGACGCGGGCAGCCGCG
ATGAGAAGGCCGAGGCGGGAGAGGCGGGACAGGCCACGGCAGAGGCTGAGTGTCACAGGACTCGGGAGACCCTGCCTCCGTTCCCGACAC
GCCTCCTGGAGCTGATTGAGGGCTTTATGCTATCCAAGGGCCTGCTCACCGCTTGCAAACTGAAGGTGTTCGATTTGTTAAAAGATGAAG
CACCCCAGAAGGCTGCGGATATTGCCAGCAAAGTGGACGCCTCTGCGTGTGGAATGGAGAGGCTTCTGGACATCTGTGCTGCCATGGGGC
TCCTGGAGAAGACAGAGCAAGGTTACAGTAACACAGAGACAGCGAACGTCTACCTGGCATCGGATGGCGAATACTCTCTGCACGGCTTCA
TCATGCACAATAATGACCTCACATGGAACCTCTTTACATACCTGGAGTTTGCCATCCGAGAGGGAACAAACCAGCACCACAGGGCGTTGG
GGAAGAAGGCGGAAGATCTGTTCCAGATTTCAGATCAGAACCACAGCTACCCAAGAAAACCCATCTCCAAATTGTGTATGGATTCACGTG
TCAGTCATTTATGACCAACTGTGTAGTGTGCCCTCATATAGTATTTGTGAGAAGAAGTTTTCAATGTAAGAGGAAGGGTGGAGAAGGAGA
GAGAAATATGTGAGGTAGTAAGGAGGACAGAAAACAGAACAGAAAAGAGTAACAGCTGAGGTCAAGATAAATGCAGAAAATGTTTAGAGA
GCTTGGCCAACTGTAATCTTAACCAAGAAATTGAAGGGAGAGGCTGTGATTTCTGTATTTGTCGACCTACAGGTAGGCTAGTATTATTTT
TCTAGTTAGTAGATCCCTAGACATGGAATCAGGGCAGCCAAGCTTGAGTTTTTATTTTTTATTTATTTATTTTTTTGAGATAGGGTCTCA
CTTTGTTACCCAGGCTGGAGTGCAGTGGCACAATCTCGACTCACTGCAGCTATCTCTCGCCTCAGCCCCTCAAGTAGCTGGGACTACAGG
TGCATGCCACCATGCCAGGCTAATTTTTGGTGTTTTTTGTAGAGACTGGGTTTTGCCATGTTGACCAAGCTGGTCTCTAACTCCTGGGCT
TAAGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCCACCACACCTGGCCCCAAGCTTGAATTTTCATTCTGC
CATTGACTTGGCATTTACCTTGGGTAAGCCATAAGCGAATCTTAATTTCTGGCTCTATCAGAGTTGTTTCATGCTCAACAATGCCATTGA
AGTGCACGGTGTGTTGCCACGATTTGACCCTCAACTTCTAGCAGTATATCAGTTATGAACTGAGGGTGAAATATATTTCTGAATAGCTAA
ATGAAGAAATGGGAAAAAATCTTCACCACAGTCAGAGCAATTTTATTATTTTCATCAGTATGATCATAATTATGATTATCATCTTAGTAA
AAAGCAGGAACTCCTACTTTTTCTTTATCAATTAAATAGCTCAGAGAGTACATCTGCCATATCTCTAATAGAATCTTTTTTTTTTTTTTT
TTTTTTGAGACAGAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAACGGCACGATCTCGGCTCACCGCAACCTCCGCCCCCTGGGTTCAA
GCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGTCAGGCACCACCACACCCGGCTAATTTTGTATTTTTTTAGTAGAGACA
GGGTTTCTCCATGTCGGTCAGGGTAGTCCCGAACTCCTGACCTCAAGTGATCTGCCTGCCTCGGCCTCCCAAGTGCTGGGATTACAGGCG
TGAGCCACTGCACCCAGCCTAGAATCTTGTATAATATGTAATTGTAGGGAAACTGCTCTCATAGGAAAGTTTTCTGCTTTTTAAATACAA
AAATACATAAAAATACATAAAATCTGATGATGAATATAAAAAAGTAACCAACCTCATTGGAACAAGTATTAACATTTTGGAATATGTTTT
ATTAGTTTTGTGATGTACTGTTTTACAATTTTTACCATTTTTTTCAGTAATTACTGTAAAATGGTATTATTGGAATGAAACTATATTTCC
TCATGTGCTGATTTGTCTTATTTTTTTCATACTTTCCCACTGGTGCTATTTTTATTTCCAATGGATATTTCTGTATTACTAGGGAGGCAT
TTACAGTCCTCTAATGTTGATTAATATGTGAAAAGAAATTGTACCAATTTTACTAAATTATGCAGTTTAAAATGGATGATTTTATGTTAT

>7168_7168_2_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000381333_CLEC7A_chr12_10271189_ENST00000353231_length(amino acids)=451AA_BP=425
MFFLQPRCAHRGLRAQKCGRPAPGVDAMVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAMETAK
QKALEVANRLYQTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEP
MDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEK
AEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLE
KTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQISDQNHSYPRKPISKLCMDSRVSH

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>7168_7168_3_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000416733_CLEC7A_chr12_10271189_ENST00000304084_length(transcript)=1579nt_BP=1215nt
AGAAGTGCGGACGCCCGGCTCCCGGCGTGGACGCCATGGTGCTGTGCCCGGTGATTGGGAAGCTGCTGCACAAGCGCGTGGTGCTGGCCA
GCGCCTCCCCACGCCGTCAGGAGATCCTCAGCAACGCGGGTCTCAGGTTTGAGGTGGTCCCCTCCAAGTTTAAAGAGAAGCTGGACAAAG
CCTCCTTCGCTACTCCGTATGGGTACGCCATGGAGACCGCCAAGCAGAAGGCCCTGGAGGTGGCCAACCGGCTGTACCAGAAAGACCTGC
GGGCCCCCGACGTGGTCATTGGAGCGGACACGATCGTGGTTGAGTGGGAGAGAACACAGCGTGTTCACAGGTGTCGCGATCGTCCACTGC
TCCAGCAAAGACCATCAGCTGGACACCAGGGTCTCGGAATTCTACGAGGAAACGAAGGTGAAGTTCTCGGAGCTGTCCGAGGAGCTGCTC
TGGGAATACGTCCACAGCGGGGAGCCCATGGACAAAGCTGGCGGCTACGGGATCCAGGCCCTGGGCGGCATGCTGGTGGAGTCCGTACAC
GGGGACTTTCTGAACGTGGTGGGATTCCCGCTGAACCACTTCTGCAAGCAGCTGGTGAAGCTCTACTACCCGCCCCGTCCGGAGGACCTG
CGGCGGAGTGTCAAGCACGACTCCATCCCGGCCGCGGACACCTTCGAAGACCTCAGTGACGTGGAGGGGGGCGGCTCGGAGCCCACTCAG
AGGGACGCGGGCAGCCGCGATGAGAAGGCCGAGGCGGGAGAGGCGGGACAGGCCACGGCAGAGGCTGAGTGTCACAGGACTCGGGAGACC
CTGCCTCCGTTCCCGACACGCCTCCTGGAGCTGATTGAGGGCTTTATGCTATCCAAGGGCCTGCTCACCGCTTGCAAACTGAAGGTGTTC
GATTTGTTAAAAGATGAAGCACCCCAGAAGGCTGCGGATATTGCCAGCAAAGTGGACGCCTCTGCGTGTGGAATGGAGAGGCTTCTGGAC
ATCTGTGCTGCCATGGGGCTCCTGGAGAAGACAGAGCAAGGTTACAGTAACACAGAGACAGCGAACGTCTACCTGGCATCGGATGGCGAA
TACTCTCTGCACGGCTTCATCATGCACAATAATGACCTCACATGGAACCTCTTTACATACCTGGAGTTTGCCATCCGAGAGGGAACAAAC
CAGCACCACAGGGCGTTGGGGAAGAAGGCGGAAGATCTGTTCCAGATTTCAGATCAGAACCACAGCTACCCAAGAAAACCCATCTCCAAA
TTGTGTATGGATTCACGTGTCAGTCATTTATGACCAACTGTGTAGTGTGCCCTCATATAGTATTTGTGAGAAGAAGTTTTCAATGTAAGA
GGAAGGGTGGAGAAGGAGAGAGAAATATGTGAGGTAGTAAGGAGGACAGAAAACAGAACAGAAAAGAGTAACAGCTGAGGTCAAGATAAA
TGCAGAAAATGTTTAGAGAGCTTGGCCAACTGTAATCTTAACCAAGAAATTGAAGGGAGAGGCTGTGATTTCTGTATTTGTCGACCTACA

>7168_7168_3_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000416733_CLEC7A_chr12_10271189_ENST00000304084_length(amino acids)=412AA_BP=386
MGSCCTSAWCWPAPPHAVRRSSATRVSGLRWSPPSLKRSWTKPPSLLRMGTPWRPPSRRPWRWPTGCTRKTCGPPTWSLERTRSWLSGRE
HSVFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQL
VKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLS
KGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLF

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>7168_7168_4_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000416733_CLEC7A_chr12_10271189_ENST00000533022_length(transcript)=1348nt_BP=1215nt
AGAAGTGCGGACGCCCGGCTCCCGGCGTGGACGCCATGGTGCTGTGCCCGGTGATTGGGAAGCTGCTGCACAAGCGCGTGGTGCTGGCCA
GCGCCTCCCCACGCCGTCAGGAGATCCTCAGCAACGCGGGTCTCAGGTTTGAGGTGGTCCCCTCCAAGTTTAAAGAGAAGCTGGACAAAG
CCTCCTTCGCTACTCCGTATGGGTACGCCATGGAGACCGCCAAGCAGAAGGCCCTGGAGGTGGCCAACCGGCTGTACCAGAAAGACCTGC
GGGCCCCCGACGTGGTCATTGGAGCGGACACGATCGTGGTTGAGTGGGAGAGAACACAGCGTGTTCACAGGTGTCGCGATCGTCCACTGC
TCCAGCAAAGACCATCAGCTGGACACCAGGGTCTCGGAATTCTACGAGGAAACGAAGGTGAAGTTCTCGGAGCTGTCCGAGGAGCTGCTC
TGGGAATACGTCCACAGCGGGGAGCCCATGGACAAAGCTGGCGGCTACGGGATCCAGGCCCTGGGCGGCATGCTGGTGGAGTCCGTACAC
GGGGACTTTCTGAACGTGGTGGGATTCCCGCTGAACCACTTCTGCAAGCAGCTGGTGAAGCTCTACTACCCGCCCCGTCCGGAGGACCTG
CGGCGGAGTGTCAAGCACGACTCCATCCCGGCCGCGGACACCTTCGAAGACCTCAGTGACGTGGAGGGGGGCGGCTCGGAGCCCACTCAG
AGGGACGCGGGCAGCCGCGATGAGAAGGCCGAGGCGGGAGAGGCGGGACAGGCCACGGCAGAGGCTGAGTGTCACAGGACTCGGGAGACC
CTGCCTCCGTTCCCGACACGCCTCCTGGAGCTGATTGAGGGCTTTATGCTATCCAAGGGCCTGCTCACCGCTTGCAAACTGAAGGTGTTC
GATTTGTTAAAAGATGAAGCACCCCAGAAGGCTGCGGATATTGCCAGCAAAGTGGACGCCTCTGCGTGTGGAATGGAGAGGCTTCTGGAC
ATCTGTGCTGCCATGGGGCTCCTGGAGAAGACAGAGCAAGGTTACAGTAACACAGAGACAGCGAACGTCTACCTGGCATCGGATGGCGAA
TACTCTCTGCACGGCTTCATCATGCACAATAATGACCTCACATGGAACCTCTTTACATACCTGGAGTTTGCCATCCGAGAGGGAACAAAC
CAGCACCACAGGGCGTTGGGGAAGAAGGCGGAAGATCTGTTCCAGATTTCAGATCAGAACCACAGCTACCCAAGAAAACCCATCTCCAAA

>7168_7168_4_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000416733_CLEC7A_chr12_10271189_ENST00000533022_length(amino acids)=412AA_BP=386
MGSCCTSAWCWPAPPHAVRRSSATRVSGLRWSPPSLKRSWTKPPSLLRMGTPWRPPSRRPWRWPTGCTRKTCGPPTWSLERTRSWLSGRE
HSVFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQL
VKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLS
KGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLF

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>7168_7168_5_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000534940_CLEC7A_chr12_10271189_ENST00000304084_length(transcript)=1661nt_BP=1297nt
ATCTCCACTCCCCTCCCACCAGGCACGAGGACATCCCCATCCCCACGCCACTCGCACCGGGTCCGCGGGGAACCCCCTATCTCTACCTTC
CCCGACGCGGCTCCCACAAGACCCCCATCTCTGCGCCGGGCCCCTCCACGTGCGGGGTCTCAGGTTTGAGGTGGTCCCCTCCAAGTTTAA
AGAGAAGCTGGACAAAGCCTCCTTCGCTACTCCGTATGGGTACGCCATGGAGACCGCCAAGCAGAAGGCCCTGGAGGTGGCCAACCGGCT
GTACCAGAAAGACCTGCGGGCCCCCGACGTGGTCATTGGAGCGGACACGATCGTGACAGTCGGGGGGCTGATTCTGGAGAAGCCGGTGGA
CAAGCAGGACGCCTACAGGATGCTGTCCCGGTTGAGTGGGAGAGAACACAGCGTGTTCACAGGTGTCGCGATCGTCCACTGCTCCAGCAA
AGACCATCAGCTGGACACCAGGGTCTCGGAATTCTACGAGGAAACGAAGGTGAAGTTCTCGGAGCTGTCCGAGGAGCTGCTCTGGGAATA
CGTCCACAGCGGGGAGCCCATGGACAAAGCTGGCGGCTACGGGATCCAGGCCCTGGGCGGCATGCTGGTGGAGTCCGTACACGGGGACTT
TCTGAACGTGGTGGGATTCCCGCTGAACCACTTCTGCAAGCAGCTGGTGAAGCTCTACTACCCGCCCCGTCCGGAGGACCTGCGGCGGAG
TGTCAAGCACGACTCCATCCCGGCCGCGGACACCTTCGAAGACCTCAGTGACGTGGAGGGGGGCGGCTCGGAGCCCACTCAGAGGGACGC
GGGCAGCCGCGATGAGAAGGCCGAGGCGGGAGAGGCGGGACAGGCCACGGCAGAGGCTGAGTGTCACAGGACTCGGGAGACCCTGCCTCC
GTTCCCGACACGCCTCCTGGAGCTGATTGAGGGCTTTATGCTATCCAAGGGCCTGCTCACCGCTTGCAAACTGAAGGTGTTCGATTTGTT
AAAAGATGAAGCACCCCAGAAGGCTGCGGATATTGCCAGCAAAGTGGACGCCTCTGCGTGTGGAATGGAGAGGCTTCTGGACATCTGTGC
TGCCATGGGGCTCCTGGAGAAGACAGAGCAAGGTTACAGTAACACAGAGACAGCGAACGTCTACCTGGCATCGGATGGCGAATACTCTCT
GCACGGCTTCATCATGCACAATAATGACCTCACATGGAACCTCTTTACATACCTGGAGTTTGCCATCCGAGAGGGAACAAACCAGCACCA
CAGGGCGTTGGGGAAGAAGGCGGAAGATCTGTTCCAGATTTCAGATCAGAACCACAGCTACCCAAGAAAACCCATCTCCAAATTGTGTAT
GGATTCACGTGTCAGTCATTTATGACCAACTGTGTAGTGTGCCCTCATATAGTATTTGTGAGAAGAAGTTTTCAATGTAAGAGGAAGGGT
GGAGAAGGAGAGAGAAATATGTGAGGTAGTAAGGAGGACAGAAAACAGAACAGAAAAGAGTAACAGCTGAGGTCAAGATAAATGCAGAAA
ATGTTTAGAGAGCTTGGCCAACTGTAATCTTAACCAAGAAATTGAAGGGAGAGGCTGTGATTTCTGTATTTGTCGACCTACAGGTAGGCT

>7168_7168_5_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000534940_CLEC7A_chr12_10271189_ENST00000304084_length(amino acids)=395AA_BP=369
MDKASFATPYGYAMETAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDH
QLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVK
HDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKD
EAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRA

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>7168_7168_6_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000534940_CLEC7A_chr12_10271189_ENST00000533022_length(transcript)=1430nt_BP=1297nt
ATCTCCACTCCCCTCCCACCAGGCACGAGGACATCCCCATCCCCACGCCACTCGCACCGGGTCCGCGGGGAACCCCCTATCTCTACCTTC
CCCGACGCGGCTCCCACAAGACCCCCATCTCTGCGCCGGGCCCCTCCACGTGCGGGGTCTCAGGTTTGAGGTGGTCCCCTCCAAGTTTAA
AGAGAAGCTGGACAAAGCCTCCTTCGCTACTCCGTATGGGTACGCCATGGAGACCGCCAAGCAGAAGGCCCTGGAGGTGGCCAACCGGCT
GTACCAGAAAGACCTGCGGGCCCCCGACGTGGTCATTGGAGCGGACACGATCGTGACAGTCGGGGGGCTGATTCTGGAGAAGCCGGTGGA
CAAGCAGGACGCCTACAGGATGCTGTCCCGGTTGAGTGGGAGAGAACACAGCGTGTTCACAGGTGTCGCGATCGTCCACTGCTCCAGCAA
AGACCATCAGCTGGACACCAGGGTCTCGGAATTCTACGAGGAAACGAAGGTGAAGTTCTCGGAGCTGTCCGAGGAGCTGCTCTGGGAATA
CGTCCACAGCGGGGAGCCCATGGACAAAGCTGGCGGCTACGGGATCCAGGCCCTGGGCGGCATGCTGGTGGAGTCCGTACACGGGGACTT
TCTGAACGTGGTGGGATTCCCGCTGAACCACTTCTGCAAGCAGCTGGTGAAGCTCTACTACCCGCCCCGTCCGGAGGACCTGCGGCGGAG
TGTCAAGCACGACTCCATCCCGGCCGCGGACACCTTCGAAGACCTCAGTGACGTGGAGGGGGGCGGCTCGGAGCCCACTCAGAGGGACGC
GGGCAGCCGCGATGAGAAGGCCGAGGCGGGAGAGGCGGGACAGGCCACGGCAGAGGCTGAGTGTCACAGGACTCGGGAGACCCTGCCTCC
GTTCCCGACACGCCTCCTGGAGCTGATTGAGGGCTTTATGCTATCCAAGGGCCTGCTCACCGCTTGCAAACTGAAGGTGTTCGATTTGTT
AAAAGATGAAGCACCCCAGAAGGCTGCGGATATTGCCAGCAAAGTGGACGCCTCTGCGTGTGGAATGGAGAGGCTTCTGGACATCTGTGC
TGCCATGGGGCTCCTGGAGAAGACAGAGCAAGGTTACAGTAACACAGAGACAGCGAACGTCTACCTGGCATCGGATGGCGAATACTCTCT
GCACGGCTTCATCATGCACAATAATGACCTCACATGGAACCTCTTTACATACCTGGAGTTTGCCATCCGAGAGGGAACAAACCAGCACCA
CAGGGCGTTGGGGAAGAAGGCGGAAGATCTGTTCCAGATTTCAGATCAGAACCACAGCTACCCAAGAAAACCCATCTCCAAATTGTGTAT

>7168_7168_6_ASMTL-CLEC7A_ASMTL_chrY_1490551_ENST00000534940_CLEC7A_chr12_10271189_ENST00000533022_length(amino acids)=395AA_BP=369
MDKASFATPYGYAMETAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDH
QLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVK
HDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKD
EAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRA

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Fusion Gene PPI Analysis for ASMTL-CLEC7A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ASMTL-CLEC7A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ASMTL-CLEC7A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource