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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RAD51B-GPHN (FusionGDB2 ID:71744)

Fusion Gene Summary for RAD51B-GPHN

check button Fusion gene summary
Fusion gene informationFusion gene name: RAD51B-GPHN
Fusion gene ID: 71744
HgeneTgene
Gene symbol

RAD51B

GPHN

Gene ID

5890

10243

Gene nameRAD51 paralog Bgephyrin
SynonymsR51H2|RAD51L1|REC2GEPH|GPH|GPHRYN|HKPX1|MOCODC
Cytomap

14q24.1

14q23.3-q24.1

Type of geneprotein-codingprotein-coding
DescriptionDNA repair protein RAD51 homolog 2RAD51 homolog BRecA-like proteinrecombination repair proteingephyrin
Modification date2020031320200313
UniProtAcc.

Q9NQX3

Ensembl transtripts involved in fusion geneENST00000469165, ENST00000390683, 
ENST00000471583, ENST00000487270, 
ENST00000487861, ENST00000488612, 
ENST00000315266, ENST00000478722, 
ENST00000544752, ENST00000305960, 
ENST00000459628, ENST00000543237, 
Fusion gene scores* DoF score22 X 15 X 11=363042 X 51 X 15=32130
# samples 2262
** MAII scorelog2(22/3630*10)=-4.04439411935845
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(62/32130*10)=-5.69550895508454
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RAD51B [Title/Abstract] AND GPHN [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRAD51B(68353921)-GPHN(67626132), # samples:6
GPHN(67243239)-RAD51B(68301797), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneGPHN

GO:0032324

molybdopterin cofactor biosynthetic process

26613940

TgeneGPHN

GO:0097112

gamma-aminobutyric acid receptor clustering

26613940


check buttonFusion gene breakpoints across RAD51B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GPHN (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-43-A474-01ARAD51Bchr14

68353921

-GPHNchr14

67626132

+
ChimerDB4LUSCTCGA-43-A474-01ARAD51Bchr14

68353921

+GPHNchr14

67626132

+
ChimerDB4LUSCTCGA-43-A474RAD51Bchr14

68353921

+GPHNchr14

67626132

+
ChimerDB4STADTCGA-IP-7968-01ARAD51Bchr14

68353921

-GPHNchr14

67626132

+
ChimerDB4STADTCGA-IP-7968-01ARAD51Bchr14

68353921

+GPHNchr14

67626132

+


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Fusion Gene ORF analysis for RAD51B-GPHN

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000469165ENST00000315266RAD51Bchr14

68353921

+GPHNchr14

67626132

+
3UTR-3CDSENST00000469165ENST00000478722RAD51Bchr14

68353921

+GPHNchr14

67626132

+
3UTR-3UTRENST00000469165ENST00000544752RAD51Bchr14

68353921

+GPHNchr14

67626132

+
3UTR-intronENST00000469165ENST00000305960RAD51Bchr14

68353921

+GPHNchr14

67626132

+
3UTR-intronENST00000469165ENST00000459628RAD51Bchr14

68353921

+GPHNchr14

67626132

+
3UTR-intronENST00000469165ENST00000543237RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-3UTRENST00000390683ENST00000544752RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-3UTRENST00000471583ENST00000544752RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-3UTRENST00000487270ENST00000544752RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-3UTRENST00000487861ENST00000544752RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-3UTRENST00000488612ENST00000544752RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000390683ENST00000305960RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000390683ENST00000459628RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000390683ENST00000543237RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000471583ENST00000305960RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000471583ENST00000459628RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000471583ENST00000543237RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000487270ENST00000305960RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000487270ENST00000459628RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000487270ENST00000543237RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000487861ENST00000305960RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000487861ENST00000459628RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000487861ENST00000543237RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000488612ENST00000305960RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000488612ENST00000459628RAD51Bchr14

68353921

+GPHNchr14

67626132

+
5CDS-intronENST00000488612ENST00000543237RAD51Bchr14

68353921

+GPHNchr14

67626132

+
In-frameENST00000390683ENST00000315266RAD51Bchr14

68353921

+GPHNchr14

67626132

+
In-frameENST00000390683ENST00000478722RAD51Bchr14

68353921

+GPHNchr14

67626132

+
In-frameENST00000471583ENST00000315266RAD51Bchr14

68353921

+GPHNchr14

67626132

+
In-frameENST00000471583ENST00000478722RAD51Bchr14

68353921

+GPHNchr14

67626132

+
In-frameENST00000487270ENST00000315266RAD51Bchr14

68353921

+GPHNchr14

67626132

+
In-frameENST00000487270ENST00000478722RAD51Bchr14

68353921

+GPHNchr14

67626132

+
In-frameENST00000487861ENST00000315266RAD51Bchr14

68353921

+GPHNchr14

67626132

+
In-frameENST00000487861ENST00000478722RAD51Bchr14

68353921

+GPHNchr14

67626132

+
In-frameENST00000488612ENST00000315266RAD51Bchr14

68353921

+GPHNchr14

67626132

+
In-frameENST00000488612ENST00000478722RAD51Bchr14

68353921

+GPHNchr14

67626132

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000487861RAD51Bchr1468353921+ENST00000315266GPHNchr1467626132+2168833291306425
ENST00000487861RAD51Bchr1468353921+ENST00000478722GPHNchr1467626132+2173833291306425
ENST00000471583RAD51Bchr1468353921+ENST00000315266GPHNchr1467626132+213980401277425
ENST00000471583RAD51Bchr1468353921+ENST00000478722GPHNchr1467626132+214480401277425
ENST00000487270RAD51Bchr1468353921+ENST00000315266GPHNchr1467626132+213980401277425
ENST00000487270RAD51Bchr1468353921+ENST00000478722GPHNchr1467626132+214480401277425
ENST00000488612RAD51Bchr1468353921+ENST00000315266GPHNchr1467626132+211878301256418
ENST00000488612RAD51Bchr1468353921+ENST00000478722GPHNchr1467626132+212378301256418
ENST00000390683RAD51Bchr1468353921+ENST00000315266GPHNchr1467626132+209175601229409
ENST00000390683RAD51Bchr1468353921+ENST00000478722GPHNchr1467626132+209675601229409

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000487861ENST00000315266RAD51Bchr1468353921+GPHNchr1467626132+0.0004023030.9995977
ENST00000487861ENST00000478722RAD51Bchr1468353921+GPHNchr1467626132+0.0003893820.9996106
ENST00000471583ENST00000315266RAD51Bchr1468353921+GPHNchr1467626132+0.0004103030.99958974
ENST00000471583ENST00000478722RAD51Bchr1468353921+GPHNchr1467626132+0.000399690.99960035
ENST00000487270ENST00000315266RAD51Bchr1468353921+GPHNchr1467626132+0.0004103030.99958974
ENST00000487270ENST00000478722RAD51Bchr1468353921+GPHNchr1467626132+0.000399690.99960035
ENST00000488612ENST00000315266RAD51Bchr1468353921+GPHNchr1467626132+0.0004369770.99956304
ENST00000488612ENST00000478722RAD51Bchr1468353921+GPHNchr1467626132+0.0004239330.99957603
ENST00000390683ENST00000315266RAD51Bchr1468353921+GPHNchr1467626132+0.0004060960.9995939
ENST00000390683ENST00000478722RAD51Bchr1468353921+GPHNchr1467626132+0.0003973630.9996026

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Fusion Genomic Features for RAD51B-GPHN


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RAD51Bchr1468353921+GPHNchr1467626131+3.38E-060.99999666
RAD51Bchr1468353921+GPHNchr1467626131+3.38E-060.99999666
RAD51Bchr1468353921+GPHNchr1467626131+3.38E-060.99999666
RAD51Bchr1468353921+GPHNchr1467626131+3.38E-060.99999666
RAD51Bchr1468353921+GPHNchr1467626131+3.38E-060.99999666
RAD51Bchr1468353921+GPHNchr1467626131+3.38E-060.99999666

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for RAD51B-GPHN


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:68353921/chr14:67626132)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.GPHN

Q9NQX3

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Acts as a major instructive molecule at inhibitory synapses, where it also clusters GABA type A receptors (PubMed:25025157, PubMed:26613940). {ECO:0000250|UniProtKB:Q03555, ECO:0000269|PubMed:25025157, ECO:0000269|PubMed:26613940}.; FUNCTION: Has also a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. {ECO:0000269|PubMed:26613940}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRAD51Bchr14:68353921chr14:67626132ENST00000390683+610108_115252367.0Nucleotide bindingATP
HgeneRAD51Bchr14:68353921chr14:67626132ENST00000471583+711108_115252351.0Nucleotide bindingATP
HgeneRAD51Bchr14:68353921chr14:67626132ENST00000487270+711108_115252385.0Nucleotide bindingATP
HgeneRAD51Bchr14:68353921chr14:67626132ENST00000488612+712108_115252495.6666666666667Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneGPHNchr14:68353921chr14:67626132ENST00000315266162214_166579737.0RegionNote=MPT Mo-transferase
TgeneGPHNchr14:68353921chr14:67626132ENST000003152661622326_736579737.0RegionNote=MPT adenylyltransferase
TgeneGPHNchr14:68353921chr14:67626132ENST00000478722172314_166612770.0RegionNote=MPT Mo-transferase
TgeneGPHNchr14:68353921chr14:67626132ENST000004787221723326_736612770.0RegionNote=MPT adenylyltransferase


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Fusion Gene Sequence for RAD51B-GPHN


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>71744_71744_1_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000390683_GPHN_chr14_67626132_ENST00000315266_length(transcript)=2091nt_BP=756nt
ATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTT
TTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGT
GCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTG
GACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATG
ATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAA
AGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTAT
CGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGAC
TCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCC
TCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCAGACTATCTCAAGCAGGTGCTGGACATTGATCTTCATGCTCAGATCCATTTTGGC
AGGGTTTTTATGAAACCAGGCTTGCCAACAACATTTGCAACTTTGGATATTGATGGTGTAAGAAAAATAATCTTTGCACTACCTGGGAAT
CCTGTATCGGCTGTGGTCACCTGCAATCTCTTTGTTGTGCCTGCACTGAGGAAAATGCAGGGCATCTTGGATCCTCGGCCAACCATCATC
AAAGCAAGGTTATCATGTGATGTAAAACTTGATCCTCGTCCAGAATACCATCGGTGTATACTAACTTGGCATCACCAAGAACCACTACCT
TGGGCACAGAGTACAGGTAATCAAATGAGCAGCCGTCTGATGAGCATGCGCAGTGCCAATGGATTGTTGATGCTACCTCCAAAGACAGAA
CAGTACGTGGAGCTCCACAAAGGCGAGGTGGTGGATGTCATGGTCATTGGACGGCTATGATGGTCACCAGCAGGAGAAAGCTTTGATGCA
TGTCCACATATCATTGACTGTATCCTGTAATATGCAACGGCACAGCTAGTTTTCCCGATTTGGATAAAAGTTGATCTGTATAGTCAACAT
CTTGAACTATATTTCAAATGAATTTAAATATCTTTTAAAGAAAAAAACACCTAAAAATAAATCTTAACAGAAAATTCTGTTCTGATTATA
TCAAGGCAAATTTTTCCTTTCTTGCAAATTGCTTTGTGTGTTCAATGCTAGGTCTGATAGCGATAGCTTTTAGTAGACAGCGGTAGGTGC
CTGCAGAACTTGTGTTTTTCTCATCTTTAAAATACAACTACTTATGCTCTTAAATCAAGGCTGTCTGCTTATTTATACTAGCGTAGGCAA
CACTTGGATTTCCCTTCTTAGTATGCTTCATAACTGCTTTACAGAGAGCTTTTGCTTGTTCTTTCTCATGTATCTCGTGTTTATGTGCAC
AGTGCCAAAAGAAGACTGACTGGGTGGAGGCTCTGCCTTGCCTCAAGAACCATCCCCTGCAGAGCATCCAGGGAGGTTTCTCGCCCCAAT
AGCCTCACGGCACAGTACTCTTGGGCAGTAACTGGACACCTTTTATTTGAAGAAACAAACTGAAGAAAAAATGCTTCCTTAAGTGCTGAC
AGCCTTTTTAACCAATACATTTAAAATTGTACAGAACAAAAAAATAAAATCAAAGACTGATCTTGTACAGATATTAGTGTTACCAGCATT
CATGTGGAAATCAAGAGCAAAGACAAAATAATGTTAAACAATTCTGTACCATAACATTTTCTGTAATGATACTGAAACTTAATGAATAAA

>71744_71744_1_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000390683_GPHN_chr14_67626132_ENST00000315266_length(amino acids)=409AA_BP=252
MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSADFSPAFLSTTLSAL
DEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKVHLY
RELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPDYLKQVLDIDLHAQIHFG
RVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLP

--------------------------------------------------------------
>71744_71744_2_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000390683_GPHN_chr14_67626132_ENST00000478722_length(transcript)=2096nt_BP=756nt
ATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTT
TTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGT
GCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTG
GACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATG
ATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAA
AGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTAT
CGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGAC
TCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCC
TCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCAGACTATCTCAAGCAGGTGCTGGACATTGATCTTCATGCTCAGATCCATTTTGGC
AGGGTTTTTATGAAACCAGGCTTGCCAACAACATTTGCAACTTTGGATATTGATGGTGTAAGAAAAATAATCTTTGCACTACCTGGGAAT
CCTGTATCGGCTGTGGTCACCTGCAATCTCTTTGTTGTGCCTGCACTGAGGAAAATGCAGGGCATCTTGGATCCTCGGCCAACCATCATC
AAAGCAAGGTTATCATGTGATGTAAAACTTGATCCTCGTCCAGAATACCATCGGTGTATACTAACTTGGCATCACCAAGAACCACTACCT
TGGGCACAGAGTACAGGTAATCAAATGAGCAGCCGTCTGATGAGCATGCGCAGTGCCAATGGATTGTTGATGCTACCTCCAAAGACAGAA
CAGTACGTGGAGCTCCACAAAGGCGAGGTGGTGGATGTCATGGTCATTGGACGGCTATGATGGTCACCAGCAGGAGAAAGCTTTGATGCA
TGTCCACATATCATTGACTGTATCCTGTAATATGCAACGGCACAGCTAGTTTTCCCGATTTGGATAAAAGTTGATCTGTATAGTCAACAT
CTTGAACTATATTTCAAATGAATTTAAATATCTTTTAAAGAAAAAAACACCTAAAAATAAATCTTAACAGAAAATTCTGTTCTGATTATA
TCAAGGCAAATTTTTCCTTTCTTGCAAATTGCTTTGTGTGTTCAATGCTAGGTCTGATAGCGATAGCTTTTAGTAGACAGCGGTAGGTGC
CTGCAGAACTTGTGTTTTTCTCATCTTTAAAATACAACTACTTATGCTCTTAAATCAAGGCTGTCTGCTTATTTATACTAGCGTAGGCAA
CACTTGGATTTCCCTTCTTAGTATGCTTCATAACTGCTTTACAGAGAGCTTTTGCTTGTTCTTTCTCATGTATCTCGTGTTTATGTGCAC
AGTGCCAAAAGAAGACTGACTGGGTGGAGGCTCTGCCTTGCCTCAAGAACCATCCCCTGCAGAGCATCCAGGGAGGTTTCTCGCCCCAAT
AGCCTCACGGCACAGTACTCTTGGGCAGTAACTGGACACCTTTTATTTGAAGAAACAAACTGAAGAAAAAATGCTTCCTTAAGTGCTGAC
AGCCTTTTTAACCAATACATTTAAAATTGTACAGAACAAAAAAATAAAATCAAAGACTGATCTTGTACAGATATTAGTGTTACCAGCATT
CATGTGGAAATCAAGAGCAAAGACAAAATAATGTTAAACAATTCTGTACCATAACATTTTCTGTAATGATACTGAAACTTAATGAATAAA

>71744_71744_2_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000390683_GPHN_chr14_67626132_ENST00000478722_length(amino acids)=409AA_BP=252
MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSADFSPAFLSTTLSAL
DEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKVHLY
RELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPDYLKQVLDIDLHAQIHFG
RVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLP

--------------------------------------------------------------
>71744_71744_3_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000471583_GPHN_chr14_67626132_ENST00000315266_length(transcript)=2139nt_BP=804nt
CTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAG
CTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTG
AGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGG
TCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACA
GAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTA
GAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTT
AACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCT
TTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTT
CAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCAGACTAT
CTCAAGCAGGTGCTGGACATTGATCTTCATGCTCAGATCCATTTTGGCAGGGTTTTTATGAAACCAGGCTTGCCAACAACATTTGCAACT
TTGGATATTGATGGTGTAAGAAAAATAATCTTTGCACTACCTGGGAATCCTGTATCGGCTGTGGTCACCTGCAATCTCTTTGTTGTGCCT
GCACTGAGGAAAATGCAGGGCATCTTGGATCCTCGGCCAACCATCATCAAAGCAAGGTTATCATGTGATGTAAAACTTGATCCTCGTCCA
GAATACCATCGGTGTATACTAACTTGGCATCACCAAGAACCACTACCTTGGGCACAGAGTACAGGTAATCAAATGAGCAGCCGTCTGATG
AGCATGCGCAGTGCCAATGGATTGTTGATGCTACCTCCAAAGACAGAACAGTACGTGGAGCTCCACAAAGGCGAGGTGGTGGATGTCATG
GTCATTGGACGGCTATGATGGTCACCAGCAGGAGAAAGCTTTGATGCATGTCCACATATCATTGACTGTATCCTGTAATATGCAACGGCA
CAGCTAGTTTTCCCGATTTGGATAAAAGTTGATCTGTATAGTCAACATCTTGAACTATATTTCAAATGAATTTAAATATCTTTTAAAGAA
AAAAACACCTAAAAATAAATCTTAACAGAAAATTCTGTTCTGATTATATCAAGGCAAATTTTTCCTTTCTTGCAAATTGCTTTGTGTGTT
CAATGCTAGGTCTGATAGCGATAGCTTTTAGTAGACAGCGGTAGGTGCCTGCAGAACTTGTGTTTTTCTCATCTTTAAAATACAACTACT
TATGCTCTTAAATCAAGGCTGTCTGCTTATTTATACTAGCGTAGGCAACACTTGGATTTCCCTTCTTAGTATGCTTCATAACTGCTTTAC
AGAGAGCTTTTGCTTGTTCTTTCTCATGTATCTCGTGTTTATGTGCACAGTGCCAAAAGAAGACTGACTGGGTGGAGGCTCTGCCTTGCC
TCAAGAACCATCCCCTGCAGAGCATCCAGGGAGGTTTCTCGCCCCAATAGCCTCACGGCACAGTACTCTTGGGCAGTAACTGGACACCTT
TTATTTGAAGAAACAAACTGAAGAAAAAATGCTTCCTTAAGTGCTGACAGCCTTTTTAACCAATACATTTAAAATTGTACAGAACAAAAA
AATAAAATCAAAGACTGATCTTGTACAGATATTAGTGTTACCAGCATTCATGTGGAAATCAAGAGCAAAGACAAAATAATGTTAAACAAT

>71744_71744_3_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000471583_GPHN_chr14_67626132_ENST00000315266_length(amino acids)=425AA_BP=268
LCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPDY
LKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRP

--------------------------------------------------------------
>71744_71744_4_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000471583_GPHN_chr14_67626132_ENST00000478722_length(transcript)=2144nt_BP=804nt
CTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAG
CTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTG
AGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGG
TCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACA
GAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTA
GAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTT
AACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCT
TTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTT
CAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCAGACTAT
CTCAAGCAGGTGCTGGACATTGATCTTCATGCTCAGATCCATTTTGGCAGGGTTTTTATGAAACCAGGCTTGCCAACAACATTTGCAACT
TTGGATATTGATGGTGTAAGAAAAATAATCTTTGCACTACCTGGGAATCCTGTATCGGCTGTGGTCACCTGCAATCTCTTTGTTGTGCCT
GCACTGAGGAAAATGCAGGGCATCTTGGATCCTCGGCCAACCATCATCAAAGCAAGGTTATCATGTGATGTAAAACTTGATCCTCGTCCA
GAATACCATCGGTGTATACTAACTTGGCATCACCAAGAACCACTACCTTGGGCACAGAGTACAGGTAATCAAATGAGCAGCCGTCTGATG
AGCATGCGCAGTGCCAATGGATTGTTGATGCTACCTCCAAAGACAGAACAGTACGTGGAGCTCCACAAAGGCGAGGTGGTGGATGTCATG
GTCATTGGACGGCTATGATGGTCACCAGCAGGAGAAAGCTTTGATGCATGTCCACATATCATTGACTGTATCCTGTAATATGCAACGGCA
CAGCTAGTTTTCCCGATTTGGATAAAAGTTGATCTGTATAGTCAACATCTTGAACTATATTTCAAATGAATTTAAATATCTTTTAAAGAA
AAAAACACCTAAAAATAAATCTTAACAGAAAATTCTGTTCTGATTATATCAAGGCAAATTTTTCCTTTCTTGCAAATTGCTTTGTGTGTT
CAATGCTAGGTCTGATAGCGATAGCTTTTAGTAGACAGCGGTAGGTGCCTGCAGAACTTGTGTTTTTCTCATCTTTAAAATACAACTACT
TATGCTCTTAAATCAAGGCTGTCTGCTTATTTATACTAGCGTAGGCAACACTTGGATTTCCCTTCTTAGTATGCTTCATAACTGCTTTAC
AGAGAGCTTTTGCTTGTTCTTTCTCATGTATCTCGTGTTTATGTGCACAGTGCCAAAAGAAGACTGACTGGGTGGAGGCTCTGCCTTGCC
TCAAGAACCATCCCCTGCAGAGCATCCAGGGAGGTTTCTCGCCCCAATAGCCTCACGGCACAGTACTCTTGGGCAGTAACTGGACACCTT
TTATTTGAAGAAACAAACTGAAGAAAAAATGCTTCCTTAAGTGCTGACAGCCTTTTTAACCAATACATTTAAAATTGTACAGAACAAAAA
AATAAAATCAAAGACTGATCTTGTACAGATATTAGTGTTACCAGCATTCATGTGGAAATCAAGAGCAAAGACAAAATAATGTTAAACAAT

>71744_71744_4_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000471583_GPHN_chr14_67626132_ENST00000478722_length(amino acids)=425AA_BP=268
LCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPDY
LKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRP

--------------------------------------------------------------
>71744_71744_5_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000487270_GPHN_chr14_67626132_ENST00000315266_length(transcript)=2139nt_BP=804nt
CTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAG
CTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTG
AGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGG
TCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACA
GAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTA
GAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTT
AACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCT
TTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTT
CAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCAGACTAT
CTCAAGCAGGTGCTGGACATTGATCTTCATGCTCAGATCCATTTTGGCAGGGTTTTTATGAAACCAGGCTTGCCAACAACATTTGCAACT
TTGGATATTGATGGTGTAAGAAAAATAATCTTTGCACTACCTGGGAATCCTGTATCGGCTGTGGTCACCTGCAATCTCTTTGTTGTGCCT
GCACTGAGGAAAATGCAGGGCATCTTGGATCCTCGGCCAACCATCATCAAAGCAAGGTTATCATGTGATGTAAAACTTGATCCTCGTCCA
GAATACCATCGGTGTATACTAACTTGGCATCACCAAGAACCACTACCTTGGGCACAGAGTACAGGTAATCAAATGAGCAGCCGTCTGATG
AGCATGCGCAGTGCCAATGGATTGTTGATGCTACCTCCAAAGACAGAACAGTACGTGGAGCTCCACAAAGGCGAGGTGGTGGATGTCATG
GTCATTGGACGGCTATGATGGTCACCAGCAGGAGAAAGCTTTGATGCATGTCCACATATCATTGACTGTATCCTGTAATATGCAACGGCA
CAGCTAGTTTTCCCGATTTGGATAAAAGTTGATCTGTATAGTCAACATCTTGAACTATATTTCAAATGAATTTAAATATCTTTTAAAGAA
AAAAACACCTAAAAATAAATCTTAACAGAAAATTCTGTTCTGATTATATCAAGGCAAATTTTTCCTTTCTTGCAAATTGCTTTGTGTGTT
CAATGCTAGGTCTGATAGCGATAGCTTTTAGTAGACAGCGGTAGGTGCCTGCAGAACTTGTGTTTTTCTCATCTTTAAAATACAACTACT
TATGCTCTTAAATCAAGGCTGTCTGCTTATTTATACTAGCGTAGGCAACACTTGGATTTCCCTTCTTAGTATGCTTCATAACTGCTTTAC
AGAGAGCTTTTGCTTGTTCTTTCTCATGTATCTCGTGTTTATGTGCACAGTGCCAAAAGAAGACTGACTGGGTGGAGGCTCTGCCTTGCC
TCAAGAACCATCCCCTGCAGAGCATCCAGGGAGGTTTCTCGCCCCAATAGCCTCACGGCACAGTACTCTTGGGCAGTAACTGGACACCTT
TTATTTGAAGAAACAAACTGAAGAAAAAATGCTTCCTTAAGTGCTGACAGCCTTTTTAACCAATACATTTAAAATTGTACAGAACAAAAA
AATAAAATCAAAGACTGATCTTGTACAGATATTAGTGTTACCAGCATTCATGTGGAAATCAAGAGCAAAGACAAAATAATGTTAAACAAT

>71744_71744_5_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000487270_GPHN_chr14_67626132_ENST00000315266_length(amino acids)=425AA_BP=268
LCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPDY
LKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRP

--------------------------------------------------------------
>71744_71744_6_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000487270_GPHN_chr14_67626132_ENST00000478722_length(transcript)=2144nt_BP=804nt
CTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAG
CTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTG
AGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGG
TCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACA
GAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTA
GAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTT
AACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCT
TTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTT
CAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCAGACTAT
CTCAAGCAGGTGCTGGACATTGATCTTCATGCTCAGATCCATTTTGGCAGGGTTTTTATGAAACCAGGCTTGCCAACAACATTTGCAACT
TTGGATATTGATGGTGTAAGAAAAATAATCTTTGCACTACCTGGGAATCCTGTATCGGCTGTGGTCACCTGCAATCTCTTTGTTGTGCCT
GCACTGAGGAAAATGCAGGGCATCTTGGATCCTCGGCCAACCATCATCAAAGCAAGGTTATCATGTGATGTAAAACTTGATCCTCGTCCA
GAATACCATCGGTGTATACTAACTTGGCATCACCAAGAACCACTACCTTGGGCACAGAGTACAGGTAATCAAATGAGCAGCCGTCTGATG
AGCATGCGCAGTGCCAATGGATTGTTGATGCTACCTCCAAAGACAGAACAGTACGTGGAGCTCCACAAAGGCGAGGTGGTGGATGTCATG
GTCATTGGACGGCTATGATGGTCACCAGCAGGAGAAAGCTTTGATGCATGTCCACATATCATTGACTGTATCCTGTAATATGCAACGGCA
CAGCTAGTTTTCCCGATTTGGATAAAAGTTGATCTGTATAGTCAACATCTTGAACTATATTTCAAATGAATTTAAATATCTTTTAAAGAA
AAAAACACCTAAAAATAAATCTTAACAGAAAATTCTGTTCTGATTATATCAAGGCAAATTTTTCCTTTCTTGCAAATTGCTTTGTGTGTT
CAATGCTAGGTCTGATAGCGATAGCTTTTAGTAGACAGCGGTAGGTGCCTGCAGAACTTGTGTTTTTCTCATCTTTAAAATACAACTACT
TATGCTCTTAAATCAAGGCTGTCTGCTTATTTATACTAGCGTAGGCAACACTTGGATTTCCCTTCTTAGTATGCTTCATAACTGCTTTAC
AGAGAGCTTTTGCTTGTTCTTTCTCATGTATCTCGTGTTTATGTGCACAGTGCCAAAAGAAGACTGACTGGGTGGAGGCTCTGCCTTGCC
TCAAGAACCATCCCCTGCAGAGCATCCAGGGAGGTTTCTCGCCCCAATAGCCTCACGGCACAGTACTCTTGGGCAGTAACTGGACACCTT
TTATTTGAAGAAACAAACTGAAGAAAAAATGCTTCCTTAAGTGCTGACAGCCTTTTTAACCAATACATTTAAAATTGTACAGAACAAAAA
AATAAAATCAAAGACTGATCTTGTACAGATATTAGTGTTACCAGCATTCATGTGGAAATCAAGAGCAAAGACAAAATAATGTTAAACAAT

>71744_71744_6_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000487270_GPHN_chr14_67626132_ENST00000478722_length(amino acids)=425AA_BP=268
LCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPDY
LKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRP

--------------------------------------------------------------
>71744_71744_7_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000487861_GPHN_chr14_67626132_ENST00000315266_length(transcript)=2168nt_BP=833nt
GTTGCTTTGCGGCGTTTTCCGCGGGGAAACTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGA
AACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCC
CACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGC
AAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGC
ATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGG
CTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAA
TAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCT
GTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTG
TGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATT
TGGCTGAGGAGTTTTCAATCCCAGACTATCTCAAGCAGGTGCTGGACATTGATCTTCATGCTCAGATCCATTTTGGCAGGGTTTTTATGA
AACCAGGCTTGCCAACAACATTTGCAACTTTGGATATTGATGGTGTAAGAAAAATAATCTTTGCACTACCTGGGAATCCTGTATCGGCTG
TGGTCACCTGCAATCTCTTTGTTGTGCCTGCACTGAGGAAAATGCAGGGCATCTTGGATCCTCGGCCAACCATCATCAAAGCAAGGTTAT
CATGTGATGTAAAACTTGATCCTCGTCCAGAATACCATCGGTGTATACTAACTTGGCATCACCAAGAACCACTACCTTGGGCACAGAGTA
CAGGTAATCAAATGAGCAGCCGTCTGATGAGCATGCGCAGTGCCAATGGATTGTTGATGCTACCTCCAAAGACAGAACAGTACGTGGAGC
TCCACAAAGGCGAGGTGGTGGATGTCATGGTCATTGGACGGCTATGATGGTCACCAGCAGGAGAAAGCTTTGATGCATGTCCACATATCA
TTGACTGTATCCTGTAATATGCAACGGCACAGCTAGTTTTCCCGATTTGGATAAAAGTTGATCTGTATAGTCAACATCTTGAACTATATT
TCAAATGAATTTAAATATCTTTTAAAGAAAAAAACACCTAAAAATAAATCTTAACAGAAAATTCTGTTCTGATTATATCAAGGCAAATTT
TTCCTTTCTTGCAAATTGCTTTGTGTGTTCAATGCTAGGTCTGATAGCGATAGCTTTTAGTAGACAGCGGTAGGTGCCTGCAGAACTTGT
GTTTTTCTCATCTTTAAAATACAACTACTTATGCTCTTAAATCAAGGCTGTCTGCTTATTTATACTAGCGTAGGCAACACTTGGATTTCC
CTTCTTAGTATGCTTCATAACTGCTTTACAGAGAGCTTTTGCTTGTTCTTTCTCATGTATCTCGTGTTTATGTGCACAGTGCCAAAAGAA
GACTGACTGGGTGGAGGCTCTGCCTTGCCTCAAGAACCATCCCCTGCAGAGCATCCAGGGAGGTTTCTCGCCCCAATAGCCTCACGGCAC
AGTACTCTTGGGCAGTAACTGGACACCTTTTATTTGAAGAAACAAACTGAAGAAAAAATGCTTCCTTAAGTGCTGACAGCCTTTTTAACC
AATACATTTAAAATTGTACAGAACAAAAAAATAAAATCAAAGACTGATCTTGTACAGATATTAGTGTTACCAGCATTCATGTGGAAATCA
AGAGCAAAGACAAAATAATGTTAAACAATTCTGTACCATAACATTTTCTGTAATGATACTGAAACTTAATGAATAAAAAAATTCCTTGAT

>71744_71744_7_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000487861_GPHN_chr14_67626132_ENST00000315266_length(amino acids)=425AA_BP=268
MCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPDY
LKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRP

--------------------------------------------------------------
>71744_71744_8_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000487861_GPHN_chr14_67626132_ENST00000478722_length(transcript)=2173nt_BP=833nt
GTTGCTTTGCGGCGTTTTCCGCGGGGAAACTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGA
AACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCC
CACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGC
AAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGC
ATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGG
CTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAA
TAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCT
GTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTG
TGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATT
TGGCTGAGGAGTTTTCAATCCCAGACTATCTCAAGCAGGTGCTGGACATTGATCTTCATGCTCAGATCCATTTTGGCAGGGTTTTTATGA
AACCAGGCTTGCCAACAACATTTGCAACTTTGGATATTGATGGTGTAAGAAAAATAATCTTTGCACTACCTGGGAATCCTGTATCGGCTG
TGGTCACCTGCAATCTCTTTGTTGTGCCTGCACTGAGGAAAATGCAGGGCATCTTGGATCCTCGGCCAACCATCATCAAAGCAAGGTTAT
CATGTGATGTAAAACTTGATCCTCGTCCAGAATACCATCGGTGTATACTAACTTGGCATCACCAAGAACCACTACCTTGGGCACAGAGTA
CAGGTAATCAAATGAGCAGCCGTCTGATGAGCATGCGCAGTGCCAATGGATTGTTGATGCTACCTCCAAAGACAGAACAGTACGTGGAGC
TCCACAAAGGCGAGGTGGTGGATGTCATGGTCATTGGACGGCTATGATGGTCACCAGCAGGAGAAAGCTTTGATGCATGTCCACATATCA
TTGACTGTATCCTGTAATATGCAACGGCACAGCTAGTTTTCCCGATTTGGATAAAAGTTGATCTGTATAGTCAACATCTTGAACTATATT
TCAAATGAATTTAAATATCTTTTAAAGAAAAAAACACCTAAAAATAAATCTTAACAGAAAATTCTGTTCTGATTATATCAAGGCAAATTT
TTCCTTTCTTGCAAATTGCTTTGTGTGTTCAATGCTAGGTCTGATAGCGATAGCTTTTAGTAGACAGCGGTAGGTGCCTGCAGAACTTGT
GTTTTTCTCATCTTTAAAATACAACTACTTATGCTCTTAAATCAAGGCTGTCTGCTTATTTATACTAGCGTAGGCAACACTTGGATTTCC
CTTCTTAGTATGCTTCATAACTGCTTTACAGAGAGCTTTTGCTTGTTCTTTCTCATGTATCTCGTGTTTATGTGCACAGTGCCAAAAGAA
GACTGACTGGGTGGAGGCTCTGCCTTGCCTCAAGAACCATCCCCTGCAGAGCATCCAGGGAGGTTTCTCGCCCCAATAGCCTCACGGCAC
AGTACTCTTGGGCAGTAACTGGACACCTTTTATTTGAAGAAACAAACTGAAGAAAAAATGCTTCCTTAAGTGCTGACAGCCTTTTTAACC
AATACATTTAAAATTGTACAGAACAAAAAAATAAAATCAAAGACTGATCTTGTACAGATATTAGTGTTACCAGCATTCATGTGGAAATCA
AGAGCAAAGACAAAATAATGTTAAACAATTCTGTACCATAACATTTTCTGTAATGATACTGAAACTTAATGAATAAAAAAATTCCTTGAT

>71744_71744_8_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000487861_GPHN_chr14_67626132_ENST00000478722_length(amino acids)=425AA_BP=268
MCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPDY
LKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRP

--------------------------------------------------------------
>71744_71744_9_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000488612_GPHN_chr14_67626132_ENST00000315266_length(transcript)=2118nt_BP=783nt
TTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGA
CATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAA
CTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCA
TTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGT
TGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATT
GACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTT
TTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCA
AAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGA
AACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCAGACTATCTCAAGCAGGTGCTGGACATT
GATCTTCATGCTCAGATCCATTTTGGCAGGGTTTTTATGAAACCAGGCTTGCCAACAACATTTGCAACTTTGGATATTGATGGTGTAAGA
AAAATAATCTTTGCACTACCTGGGAATCCTGTATCGGCTGTGGTCACCTGCAATCTCTTTGTTGTGCCTGCACTGAGGAAAATGCAGGGC
ATCTTGGATCCTCGGCCAACCATCATCAAAGCAAGGTTATCATGTGATGTAAAACTTGATCCTCGTCCAGAATACCATCGGTGTATACTA
ACTTGGCATCACCAAGAACCACTACCTTGGGCACAGAGTACAGGTAATCAAATGAGCAGCCGTCTGATGAGCATGCGCAGTGCCAATGGA
TTGTTGATGCTACCTCCAAAGACAGAACAGTACGTGGAGCTCCACAAAGGCGAGGTGGTGGATGTCATGGTCATTGGACGGCTATGATGG
TCACCAGCAGGAGAAAGCTTTGATGCATGTCCACATATCATTGACTGTATCCTGTAATATGCAACGGCACAGCTAGTTTTCCCGATTTGG
ATAAAAGTTGATCTGTATAGTCAACATCTTGAACTATATTTCAAATGAATTTAAATATCTTTTAAAGAAAAAAACACCTAAAAATAAATC
TTAACAGAAAATTCTGTTCTGATTATATCAAGGCAAATTTTTCCTTTCTTGCAAATTGCTTTGTGTGTTCAATGCTAGGTCTGATAGCGA
TAGCTTTTAGTAGACAGCGGTAGGTGCCTGCAGAACTTGTGTTTTTCTCATCTTTAAAATACAACTACTTATGCTCTTAAATCAAGGCTG
TCTGCTTATTTATACTAGCGTAGGCAACACTTGGATTTCCCTTCTTAGTATGCTTCATAACTGCTTTACAGAGAGCTTTTGCTTGTTCTT
TCTCATGTATCTCGTGTTTATGTGCACAGTGCCAAAAGAAGACTGACTGGGTGGAGGCTCTGCCTTGCCTCAAGAACCATCCCCTGCAGA
GCATCCAGGGAGGTTTCTCGCCCCAATAGCCTCACGGCACAGTACTCTTGGGCAGTAACTGGACACCTTTTATTTGAAGAAACAAACTGA
AGAAAAAATGCTTCCTTAAGTGCTGACAGCCTTTTTAACCAATACATTTAAAATTGTACAGAACAAAAAAATAAAATCAAAGACTGATCT
TGTACAGATATTAGTGTTACCAGCATTCATGTGGAAATCAAGAGCAAAGACAAAATAATGTTAAACAATTCTGTACCATAACATTTTCTG

>71744_71744_9_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000488612_GPHN_chr14_67626132_ENST00000315266_length(amino acids)=418AA_BP=261
LKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSADFSPA
FLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLL
LTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPDYLKQVLDI
DLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCIL

--------------------------------------------------------------
>71744_71744_10_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000488612_GPHN_chr14_67626132_ENST00000478722_length(transcript)=2123nt_BP=783nt
TTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGA
CATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAA
CTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCA
TTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGT
TGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATT
GACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTT
TTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCA
AAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGA
AACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCAGACTATCTCAAGCAGGTGCTGGACATT
GATCTTCATGCTCAGATCCATTTTGGCAGGGTTTTTATGAAACCAGGCTTGCCAACAACATTTGCAACTTTGGATATTGATGGTGTAAGA
AAAATAATCTTTGCACTACCTGGGAATCCTGTATCGGCTGTGGTCACCTGCAATCTCTTTGTTGTGCCTGCACTGAGGAAAATGCAGGGC
ATCTTGGATCCTCGGCCAACCATCATCAAAGCAAGGTTATCATGTGATGTAAAACTTGATCCTCGTCCAGAATACCATCGGTGTATACTA
ACTTGGCATCACCAAGAACCACTACCTTGGGCACAGAGTACAGGTAATCAAATGAGCAGCCGTCTGATGAGCATGCGCAGTGCCAATGGA
TTGTTGATGCTACCTCCAAAGACAGAACAGTACGTGGAGCTCCACAAAGGCGAGGTGGTGGATGTCATGGTCATTGGACGGCTATGATGG
TCACCAGCAGGAGAAAGCTTTGATGCATGTCCACATATCATTGACTGTATCCTGTAATATGCAACGGCACAGCTAGTTTTCCCGATTTGG
ATAAAAGTTGATCTGTATAGTCAACATCTTGAACTATATTTCAAATGAATTTAAATATCTTTTAAAGAAAAAAACACCTAAAAATAAATC
TTAACAGAAAATTCTGTTCTGATTATATCAAGGCAAATTTTTCCTTTCTTGCAAATTGCTTTGTGTGTTCAATGCTAGGTCTGATAGCGA
TAGCTTTTAGTAGACAGCGGTAGGTGCCTGCAGAACTTGTGTTTTTCTCATCTTTAAAATACAACTACTTATGCTCTTAAATCAAGGCTG
TCTGCTTATTTATACTAGCGTAGGCAACACTTGGATTTCCCTTCTTAGTATGCTTCATAACTGCTTTACAGAGAGCTTTTGCTTGTTCTT
TCTCATGTATCTCGTGTTTATGTGCACAGTGCCAAAAGAAGACTGACTGGGTGGAGGCTCTGCCTTGCCTCAAGAACCATCCCCTGCAGA
GCATCCAGGGAGGTTTCTCGCCCCAATAGCCTCACGGCACAGTACTCTTGGGCAGTAACTGGACACCTTTTATTTGAAGAAACAAACTGA
AGAAAAAATGCTTCCTTAAGTGCTGACAGCCTTTTTAACCAATACATTTAAAATTGTACAGAACAAAAAAATAAAATCAAAGACTGATCT
TGTACAGATATTAGTGTTACCAGCATTCATGTGGAAATCAAGAGCAAAGACAAAATAATGTTAAACAATTCTGTACCATAACATTTTCTG

>71744_71744_10_RAD51B-GPHN_RAD51B_chr14_68353921_ENST00000488612_GPHN_chr14_67626132_ENST00000478722_length(amino acids)=418AA_BP=261
LKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSADFSPA
FLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLL
LTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPDYLKQVLDI
DLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCIL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RAD51B-GPHN


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneRAD51Bchr14:68353921chr14:67626132ENST00000390683+6101_75252.0367.0RAD51C
HgeneRAD51Bchr14:68353921chr14:67626132ENST00000471583+7111_75252.0351.0RAD51C
HgeneRAD51Bchr14:68353921chr14:67626132ENST00000487270+7111_75252.0385.0RAD51C
HgeneRAD51Bchr14:68353921chr14:67626132ENST00000488612+7121_75252.0495.6666666666667RAD51C


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneGPHNchr14:68353921chr14:67626132ENST000003152661622140_316579.0737.0GABARAP
TgeneGPHNchr14:68353921chr14:67626132ENST000004787221723140_316612.0770.0GABARAP


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RAD51B-GPHN


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RAD51B-GPHN


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource