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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:RAD51B-MPP5 (FusionGDB2 ID:71751)

Fusion Gene Summary for RAD51B-MPP5

Fusion gene summary

Fusion gene information	Fusion gene name: RAD51B-MPP5
	Fusion gene ID: 71751
		Hgene	Tgene
	Gene symbol	RAD51B	MPP5
	Gene ID	5890	64398
	Gene name	RAD51 paralog B	membrane palmitoylated protein 5
	Synonyms	R51H2\|RAD51L1\|REC2	PALS1
	Cytomap	14q24.1	14q23.3
	Type of gene	protein-coding	protein-coding
	Description	DNA repair protein RAD51 homolog 2RAD51 homolog BRecA-like proteinrecombination repair protein	MAGUK p55 subfamily member 5membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)protein associated with Lin-7 1protein associated with lin seven 1stardust
	Modification date	20200313	20200313
	UniProtAcc	.	Q8N3R9
	Ensembl transtripts involved in fusion gene	ENST00000469165, ENST00000390683, ENST00000471583, ENST00000487270, ENST00000487861, ENST00000488612,	ENST00000261681, ENST00000555925, ENST00000554911, ENST00000556345,
Fusion gene scores	* DoF score	22 X 15 X 11=3630	5 X 7 X 6=210
	# samples	22	8
	** MAII score	log2(22/3630*10)=-4.04439411935845 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(8/210*10)=-1.39231742277876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: RAD51B [Title/Abstract] AND MPP5 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	MPP5(67779427)-RAD51B(69196525), # samples:2 RAD51B(68353921)-MPP5(67770238), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across RAD51B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across MPP5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	OV	TCGA-24-2026	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
ChimerDB4	UCEC	TCGA-B5-A11J	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+

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Fusion Gene ORF analysis for RAD51B-MPP5

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-3CDS	ENST00000469165	ENST00000261681	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
3UTR-3CDS	ENST00000469165	ENST00000555925	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
3UTR-intron	ENST00000469165	ENST00000554911	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
3UTR-intron	ENST00000469165	ENST00000556345	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
5CDS-intron	ENST00000390683	ENST00000554911	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
5CDS-intron	ENST00000390683	ENST00000556345	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
5CDS-intron	ENST00000471583	ENST00000554911	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
5CDS-intron	ENST00000471583	ENST00000556345	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
5CDS-intron	ENST00000487270	ENST00000554911	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
5CDS-intron	ENST00000487270	ENST00000556345	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
5CDS-intron	ENST00000487861	ENST00000554911	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
5CDS-intron	ENST00000487861	ENST00000556345	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
5CDS-intron	ENST00000488612	ENST00000554911	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
5CDS-intron	ENST00000488612	ENST00000556345	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
In-frame	ENST00000390683	ENST00000261681	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
In-frame	ENST00000390683	ENST00000555925	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
In-frame	ENST00000471583	ENST00000261681	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
In-frame	ENST00000471583	ENST00000555925	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
In-frame	ENST00000487270	ENST00000261681	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
In-frame	ENST00000487270	ENST00000555925	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
In-frame	ENST00000487861	ENST00000261681	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
In-frame	ENST00000487861	ENST00000555925	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
In-frame	ENST00000488612	ENST00000261681	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+
In-frame	ENST00000488612	ENST00000555925	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000487861	RAD51B	chr14	68353921	+	ENST00000261681	MPP5	chr14	67770238	+	4761	833	29	1897	622
ENST00000487861	RAD51B	chr14	68353921	+	ENST00000555925	MPP5	chr14	67770238	+	4761	833	29	1897	622
ENST00000471583	RAD51B	chr14	68353921	+	ENST00000261681	MPP5	chr14	67770238	+	4732	804	0	1868	622
ENST00000471583	RAD51B	chr14	68353921	+	ENST00000555925	MPP5	chr14	67770238	+	4732	804	0	1868	622
ENST00000487270	RAD51B	chr14	68353921	+	ENST00000261681	MPP5	chr14	67770238	+	4732	804	0	1868	622
ENST00000487270	RAD51B	chr14	68353921	+	ENST00000555925	MPP5	chr14	67770238	+	4732	804	0	1868	622
ENST00000488612	RAD51B	chr14	68353921	+	ENST00000261681	MPP5	chr14	67770238	+	4711	783	0	1847	615
ENST00000488612	RAD51B	chr14	68353921	+	ENST00000555925	MPP5	chr14	67770238	+	4711	783	0	1847	615
ENST00000390683	RAD51B	chr14	68353921	+	ENST00000261681	MPP5	chr14	67770238	+	4684	756	0	1820	606
ENST00000390683	RAD51B	chr14	68353921	+	ENST00000555925	MPP5	chr14	67770238	+	4684	756	0	1820	606

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000487861	ENST00000261681	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000167368	0.99983263
ENST00000487861	ENST00000555925	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000167368	0.99983263
ENST00000471583	ENST00000261681	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000167989	0.99983203
ENST00000471583	ENST00000555925	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000167989	0.99983203
ENST00000487270	ENST00000261681	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000167989	0.99983203
ENST00000487270	ENST00000555925	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000167989	0.99983203
ENST00000488612	ENST00000261681	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000174262	0.9998258
ENST00000488612	ENST00000555925	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000174262	0.9998258
ENST00000390683	ENST00000261681	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000168323	0.9998317
ENST00000390683	ENST00000555925	RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000168323	0.9998317

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Fusion Genomic Features for RAD51B-MPP5

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000252958	0.9997471
RAD51B	chr14	68353921	+	MPP5	chr14	67770238	+	0.000252958	0.9997471

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RAD51B-MPP5

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:67779427/chr14:69196525)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	MPP5 Q8N3R9
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (PubMed:16678097, PubMed:25385611). Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface (By similarity). Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity (PubMed:27466317). Required during embryonic and postnatal retinal development (By similarity). Required for the maintenance of cerebellar progenitor cells in an undifferentiated proliferative state, preventing premature differentiation, and is required for cerebellar histogenesis, fissure formation, cerebellar layer organization and cortical development (By similarity). Plays a role in neuronal progenitor cell survival, potentially via promotion of mTOR signaling (By similarity). Plays a role in the radial and longitudinal extension of the myelin sheath in Schwann cells (By similarity). May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter (By similarity). Plays a role in the T-cell receptor-mediated activation of NF-kappa-B (PubMed:21479189). Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton (By similarity). Required for the normal polarized localization of the vesicular marker STX4 (By similarity). Required for the correct trafficking of the myelin proteins PMP22 and MAG (By similarity). Involved in promoting phosphorylation and cytoplasmic retention of transcriptional coactivators YAP1 and WWTR1/TAZ which leads to suppression of TGFB1-dependent transcription of target genes such as CCN2/CTGF, SERPINE1/PAI1, SNAI1/SNAIL1 and SMAD7 (By similarity). {ECO:0000250\|UniProtKB:B4F7E7, ECO:0000250\|UniProtKB:Q9JLB2, ECO:0000269\|PubMed:16678097, ECO:0000269\|PubMed:21479189, ECO:0000269\|PubMed:25385611, ECO:0000269\|PubMed:27466317}.; FUNCTION: (Microbial infection) Acts as an interaction partner for human coronaviruses SARS-CoV and, probably, SARS-CoV-2 envelope protein E which results in delayed formation of tight junctions and disregulation of cell polarity. {ECO:0000269\|PubMed:20861307, ECO:0000303\|PubMed:32891874}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

RAD51B

chr14:68353921

chr14:67770238

ENST00000390683

108_115

252

367.0

Nucleotide binding

ATP

Hgene

RAD51B

chr14:68353921

chr14:67770238

ENST00000471583

108_115

252

351.0

Nucleotide binding

ATP

Hgene

RAD51B

chr14:68353921

chr14:67770238

ENST00000487270

108_115

252

385.0

Nucleotide binding

ATP

Hgene

RAD51B

chr14:68353921

chr14:67770238

ENST00000488612

108_115

252

495.6666666666667

Nucleotide binding

ATP

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000261681

345_417

321

676.0

Domain

SH3

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000261681

479_660

321

676.0

Domain

Guanylate kinase-like

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000555925

345_417

287

642.0

Domain

SH3

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000555925

479_660

287

642.0

Domain

Guanylate kinase-like

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000261681

486_493

321

676.0

Nucleotide binding

ATP

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000555925

486_493

287

642.0

Nucleotide binding

ATP

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000261681

120_177

321

676.0

Domain

L27 1

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000261681

179_235

321

676.0

Domain

L27 2

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000261681

256_336

321

676.0

Domain

PDZ

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000555925

120_177

287

642.0

Domain

L27 1

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000555925

179_235

287

642.0

Domain

L27 2

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000555925

256_336

287

642.0

Domain

PDZ

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000261681

1_345

321

676.0

Region

Required for the correct localization of MPP5 and PATJ at cell-cell contacts and the normal formation of tight junctions and adherens junctions

Tgene

MPP5

chr14:68353921

chr14:67770238

ENST00000555925

1_345

287

642.0

Region

Required for the correct localization of MPP5 and PATJ at cell-cell contacts and the normal formation of tight junctions and adherens junctions

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Fusion Gene Sequence for RAD51B-MPP5

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>71751_71751_1_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000390683_MPP5_chr14_67770238_ENST00000261681_length(transcript)=4684nt_BP=756nt
ATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTT
TTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGT
GCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTG
GACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATG
ATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAA
AGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTAT
CGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGAC
TCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCC
TCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCATCTGATATGCATGGTACTTTGACTTTTGTCCTGATTCCCAGTCAACAGATCAAG
CCGCCTCCTGCCAAGGAAACAGTAATCCATGTAAAAGCTCATTTTGACTATGACCCCTCAGATGACCCTTATGTTCCATGTCGAGAGTTA
GGTCTGTCTTTTCAAAAAGGTGATATACTTCATGTGATCAGTCAAGAAGATCCAAACTGGTGGCAGGCCTACAGGGAAGGGGACGAAGAT
AATCAACCTCTAGCCGGGCTTGTTCCAGGGAAAAGCTTTCAGCAGCAAAGGGAAGCCATGAAACAAACCATAGAAGAAGATAAGGAGCCA
GAAAAATCAGGAAAACTGTGGTGTGCAAAGAAGAATAAAAAGAAGAGGAAAAAGGTTTTATATAATGCCAATAAAAATGATGATTATGAC
AACGAGGAGATCTTAACCTATGAGGAAATGTCACTTTATCATCAGCCAGCAAATAGGAAGAGACCTATCATCTTGATTGGTCCACAGAAC
TGTGGCCAGAATGAATTGCGTCAGAGGCTCATGAACAAAGAAAAGGACCGCTTTGCATCTGCAGTTCCTCATACAACCCGGAGTAGGCGA
GACCAAGAAGTAGCCGGTAGAGATTACCACTTTGTTTCGCGGCAAGCATTCGAGGCAGACATAGCAGCTGGAAAGTTCATTGAGCATGGT
GAATTTGAGAAGAATTTGTATGGAACTAGCATAGATTCTGTACGGCAAGTGATCAACTCTGGCAAAATATGTCTTTTAAGTCTTCGTACA
CAGTCATTGAAGACTCTCCGGAATTCAGATTTGAAACCATATATTATCTTCATTGCACCCCCTTCACAAGAAAGACTTCGGGCATTATTG
GCCAAAGAAGGCAAGAATCCAAAGCCTGAAGAGTTGAGAGAAATCATTGAGAAGACAAGAGAGATGGAGCAGAACAATGGCCACTACTTT
GATACGGCAATTGTGAATTCCGATCTTGATAAAGCCTATCAGGAATTGCTTAGGTTAATTAACAAACTTGATACTGAACCTCAGTGGGTA
CCATCCACTTGGCTGAGGTGAAAGAAACATCCATTCTGTGGCATGTTGGACTTGATCTGGCAAAAACTGCCAATAGGAGGACTGCCCGAC
ACTGCAGCAAGATTGAGGATAAGATGGAAGGCAGCAGTATAAGCTGTAGATCTGTTCTTAGATCTCTTGAATTAGTGAGACGACAGTTCC
CTTAGGCAGTTTGTGCATGGCATCCTTTATTCTCTATACATGGCTTTAGCGGTTCTTGCCTCATTTTGGGATTCTAAATGGAAGCTTTCA
ACAGAGCATTCCATTTTGTCCTGTTAAAACCTTTTGTTTTCACCTAAACCCTTTCTGCTTAGTTGTATCTCTGTGAAAAACTTGTATACA
CAAGCGTCCATGTCTCACACAAATATTGATGTGATTATTCTTAAGTGTTAAATCATTAACACTTAAATGACTTCATTGGGAATATTGAGC
AGAGGGACTGTGCTTCTATGCACTGGGCAAGGCAGTATTTGCTTAGGAAACTAATTTAGTCATCAGAGATACTTTCCTAAAAAGGAAAAA
TAAAAAACAAAATGGTGCCACTTTGGGTTGAAGCTACTTTGTTAGGCTTGAATTCATTTATATGTCTTTTGATTCTTAAAAAAACAAAAA
ACATTCCATTAGAAGCACCAGTTTTTTTGCTCAGACTTTGTGGATCAGACTCTACACTCAACACACTCTAATCTACTTAAAGGTATACAA
AATATGCTGATCTTTTTTAAATTATGATTTCCTGAATTTTTTTCTTAAGTCGTCTCAACTGATTTACTCACTTAGCTTCCCTTCCCTCAT
CAGCATAGTATAATAGAATGTATGTTACATTTTTATGAATGGCAGGTGTTCATTATAATCTGTATTGACTTAAAAAGTTTCTTCCTCATG
ATGCTAATAGTTTTTTGTATACATGGGAGGATAGCACATTTGACAGTTTTTGCATTTTTATGTATGAGCACAGTATCCTATGACTGTGCT
ACGTATATATAGGTAATAAACTGGAATTCTGTTGATGAATATAGCTGCTGTACTGTATATTAATATTTAATAGATCAACAAATGGTCATT
GAAAACACTTGTTTAGCATTAGAATAAAATTATATATGTCCTTGGGAAATATTATGACAGTTGACTTTAAGATCAAAAGGAAGGGAAGAC
CTGAAAGTCATTTGAACATTTTAGGAAAAGAATATTGGAGAGAAAAAGGTATTAAATATATAGAAATAGGTTTTTAACCTAACAAGGTCT
GCCTCTTATGACGAGAATGCAACAGCTTGGTAAATCATAAAAGAAACATTTAAGCTAATAGGATTTTCGTACTGTCTCTATAGCTGTAGC
TTTAAAATTCAACGTATATAATTGGCATGGAAACTTAATTTGCAGTCTTTTCAAGCCTTTAGGATAGTGTGATGTGTAACAAACAACCTC
AAATGTGAATGCCTTGATTTTATTTTTATGGTGACTTTAGCTACAGCATTTCCTATACCCAGAGCTAAACACTGGAATAATACTGACATC
ATTTAATTTAACATAAGCAATTATGTTTAAGGAGTAATTTGTGTCATGTACATATTTGATTGATTTTTTTTCTTCTACATAATTTTATTT
GAACAAATGTAGACAGTTTATATGTCGCCTTTTTCTGTTCAAATTTGCATGGCCTATTAAGTTGGCTGGAGAGTGTTTTATGTGGAAATA
TTTTCAAGATAATGTTCCTTAGGAAGAAAATAACATTCTTGGGTTGAGGGAAGGAATGCCATACACTACTGTCTCTTCAGATCTGAAATA
CTCCAGTTTAGAGCCAGGAAATTTCACAGGTCACACCGATTTTTAGCATTAAAAACTAAGGAATATACTTAGCACTTACTTAATCTTTTC
AGTTTTCCAGTTTACGTCTCAGGAATGAAGTGTAGTCTATGGTTGACAATGGAGTTTTGTGATCCTGCTTATTGTAACTGACAACTGTTT
TCAACTCCAAGAGCTAAACTATTGGCAGTTCATGTTAAGTTAGAGTGAGGGTGTAGGTAGTGTCAGTGAGTGGCTCTTGTGCCTGCTGTA
GACATTAGGCCTGCACTAGGGCCATGTGCTGTCAAGATTCAGGAACATGGCTTTAACAAGCAGATCTTGTATCAAGGCAGAGGTGATGCC
ATGCCATACTTTTAGGAAGTCTGAGATGATAAATATTTCAAGGTCAGTGAAGTCTATCAATCATTCTCCCCTTCCTCATCAGCAATGGTA
GATAGAAATGTCCTAAACTTTTCTAAATCCTAGTGATGAGGATGTGCTGATATTCAACATAGTCCTTAAAGTGAAAACTGAGTTGTTGCT
GACCTCCACAAAAGAATATGGAAAAAAGCCTTGCTGTACACCTAGTTGTACAGCCACTCTGGCCAATTCCATTTCCTGTCCCTCTGTGGT
TCTGACTGGAGACCCCAGTGTGGGGGAGGTCTTACCATTTAATATAGAAATGATATCAATAACTAATGCTATGTACTTGGAAAATCCAAA
TAAGGAAGTTTTAGGTTGGTGCATAACTTTGTTTCTCAAATTTTCGTTGTCAGAACAAATGGAAGGAGAATATTATTTAGACTAATCCAG
ATTTGCTTTCTATGAAAATCTAATGTCTGGATTATCTTCCTTTTCTCATGGCCTAAGAAATAAGGATCAATAAGGAATGATTTGAATGTA
ATTTTGTGAATGTGTGGAAAATATAAAGCAGGGATTTAGCCTTAATAAAGGTAACCTTCTGACATCTGTTGTTAATCCCCCTTTGTACTC
TTTTCCTGTATCTGCACTGTTATTTTGAGATGTCATACTGTACACTGTATTGTAAAAATAAAAAGTAAAATTATATTTCAAATTTTAAAA

>71751_71751_1_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000390683_MPP5_chr14_67770238_ENST00000261681_length(amino acids)=606AA_BP=252
MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSADFSPAFLSTTLSAL
DEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKVHLY
RELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPSDMHGTLTFVLIPSQQIK
PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEP
EKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRR
DQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALL

--------------------------------------------------------------
>71751_71751_2_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000390683_MPP5_chr14_67770238_ENST00000555925_length(transcript)=4684nt_BP=756nt
ATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTT
TTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGT
GCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTG
GACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATG
ATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAA
AGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTAT
CGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGAC
TCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCC
TCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCATCTGATATGCATGGTACTTTGACTTTTGTCCTGATTCCCAGTCAACAGATCAAG
CCGCCTCCTGCCAAGGAAACAGTAATCCATGTAAAAGCTCATTTTGACTATGACCCCTCAGATGACCCTTATGTTCCATGTCGAGAGTTA
GGTCTGTCTTTTCAAAAAGGTGATATACTTCATGTGATCAGTCAAGAAGATCCAAACTGGTGGCAGGCCTACAGGGAAGGGGACGAAGAT
AATCAACCTCTAGCCGGGCTTGTTCCAGGGAAAAGCTTTCAGCAGCAAAGGGAAGCCATGAAACAAACCATAGAAGAAGATAAGGAGCCA
GAAAAATCAGGAAAACTGTGGTGTGCAAAGAAGAATAAAAAGAAGAGGAAAAAGGTTTTATATAATGCCAATAAAAATGATGATTATGAC
AACGAGGAGATCTTAACCTATGAGGAAATGTCACTTTATCATCAGCCAGCAAATAGGAAGAGACCTATCATCTTGATTGGTCCACAGAAC
TGTGGCCAGAATGAATTGCGTCAGAGGCTCATGAACAAAGAAAAGGACCGCTTTGCATCTGCAGTTCCTCATACAACCCGGAGTAGGCGA
GACCAAGAAGTAGCCGGTAGAGATTACCACTTTGTTTCGCGGCAAGCATTCGAGGCAGACATAGCAGCTGGAAAGTTCATTGAGCATGGT
GAATTTGAGAAGAATTTGTATGGAACTAGCATAGATTCTGTACGGCAAGTGATCAACTCTGGCAAAATATGTCTTTTAAGTCTTCGTACA
CAGTCATTGAAGACTCTCCGGAATTCAGATTTGAAACCATATATTATCTTCATTGCACCCCCTTCACAAGAAAGACTTCGGGCATTATTG
GCCAAAGAAGGCAAGAATCCAAAGCCTGAAGAGTTGAGAGAAATCATTGAGAAGACAAGAGAGATGGAGCAGAACAATGGCCACTACTTT
GATACGGCAATTGTGAATTCCGATCTTGATAAAGCCTATCAGGAATTGCTTAGGTTAATTAACAAACTTGATACTGAACCTCAGTGGGTA
CCATCCACTTGGCTGAGGTGAAAGAAACATCCATTCTGTGGCATGTTGGACTTGATCTGGCAAAAACTGCCAATAGGAGGACTGCCCGAC
ACTGCAGCAAGATTGAGGATAAGATGGAAGGCAGCAGTATAAGCTGTAGATCTGTTCTTAGATCTCTTGAATTAGTGAGACGACAGTTCC
CTTAGGCAGTTTGTGCATGGCATCCTTTATTCTCTATACATGGCTTTAGCGGTTCTTGCCTCATTTTGGGATTCTAAATGGAAGCTTTCA
ACAGAGCATTCCATTTTGTCCTGTTAAAACCTTTTGTTTTCACCTAAACCCTTTCTGCTTAGTTGTATCTCTGTGAAAAACTTGTATACA
CAAGCGTCCATGTCTCACACAAATATTGATGTGATTATTCTTAAGTGTTAAATCATTAACACTTAAATGACTTCATTGGGAATATTGAGC
AGAGGGACTGTGCTTCTATGCACTGGGCAAGGCAGTATTTGCTTAGGAAACTAATTTAGTCATCAGAGATACTTTCCTAAAAAGGAAAAA
TAAAAAACAAAATGGTGCCACTTTGGGTTGAAGCTACTTTGTTAGGCTTGAATTCATTTATATGTCTTTTGATTCTTAAAAAAACAAAAA
ACATTCCATTAGAAGCACCAGTTTTTTTGCTCAGACTTTGTGGATCAGACTCTACACTCAACACACTCTAATCTACTTAAAGGTATACAA
AATATGCTGATCTTTTTTAAATTATGATTTCCTGAATTTTTTTCTTAAGTCGTCTCAACTGATTTACTCACTTAGCTTCCCTTCCCTCAT
CAGCATAGTATAATAGAATGTATGTTACATTTTTATGAATGGCAGGTGTTCATTATAATCTGTATTGACTTAAAAAGTTTCTTCCTCATG
ATGCTAATAGTTTTTTGTATACATGGGAGGATAGCACATTTGACAGTTTTTGCATTTTTATGTATGAGCACAGTATCCTATGACTGTGCT
ACGTATATATAGGTAATAAACTGGAATTCTGTTGATGAATATAGCTGCTGTACTGTATATTAATATTTAATAGATCAACAAATGGTCATT
GAAAACACTTGTTTAGCATTAGAATAAAATTATATATGTCCTTGGGAAATATTATGACAGTTGACTTTAAGATCAAAAGGAAGGGAAGAC
CTGAAAGTCATTTGAACATTTTAGGAAAAGAATATTGGAGAGAAAAAGGTATTAAATATATAGAAATAGGTTTTTAACCTAACAAGGTCT
GCCTCTTATGACGAGAATGCAACAGCTTGGTAAATCATAAAAGAAACATTTAAGCTAATAGGATTTTCGTACTGTCTCTATAGCTGTAGC
TTTAAAATTCAACGTATATAATTGGCATGGAAACTTAATTTGCAGTCTTTTCAAGCCTTTAGGATAGTGTGATGTGTAACAAACAACCTC
AAATGTGAATGCCTTGATTTTATTTTTATGGTGACTTTAGCTACAGCATTTCCTATACCCAGAGCTAAACACTGGAATAATACTGACATC
ATTTAATTTAACATAAGCAATTATGTTTAAGGAGTAATTTGTGTCATGTACATATTTGATTGATTTTTTTTCTTCTACATAATTTTATTT
GAACAAATGTAGACAGTTTATATGTCGCCTTTTTCTGTTCAAATTTGCATGGCCTATTAAGTTGGCTGGAGAGTGTTTTATGTGGAAATA
TTTTCAAGATAATGTTCCTTAGGAAGAAAATAACATTCTTGGGTTGAGGGAAGGAATGCCATACACTACTGTCTCTTCAGATCTGAAATA
CTCCAGTTTAGAGCCAGGAAATTTCACAGGTCACACCGATTTTTAGCATTAAAAACTAAGGAATATACTTAGCACTTACTTAATCTTTTC
AGTTTTCCAGTTTACGTCTCAGGAATGAAGTGTAGTCTATGGTTGACAATGGAGTTTTGTGATCCTGCTTATTGTAACTGACAACTGTTT
TCAACTCCAAGAGCTAAACTATTGGCAGTTCATGTTAAGTTAGAGTGAGGGTGTAGGTAGTGTCAGTGAGTGGCTCTTGTGCCTGCTGTA
GACATTAGGCCTGCACTAGGGCCATGTGCTGTCAAGATTCAGGAACATGGCTTTAACAAGCAGATCTTGTATCAAGGCAGAGGTGATGCC
ATGCCATACTTTTAGGAAGTCTGAGATGATAAATATTTCAAGGTCAGTGAAGTCTATCAATCATTCTCCCCTTCCTCATCAGCAATGGTA
GATAGAAATGTCCTAAACTTTTCTAAATCCTAGTGATGAGGATGTGCTGATATTCAACATAGTCCTTAAAGTGAAAACTGAGTTGTTGCT
GACCTCCACAAAAGAATATGGAAAAAAGCCTTGCTGTACACCTAGTTGTACAGCCACTCTGGCCAATTCCATTTCCTGTCCCTCTGTGGT
TCTGACTGGAGACCCCAGTGTGGGGGAGGTCTTACCATTTAATATAGAAATGATATCAATAACTAATGCTATGTACTTGGAAAATCCAAA
TAAGGAAGTTTTAGGTTGGTGCATAACTTTGTTTCTCAAATTTTCGTTGTCAGAACAAATGGAAGGAGAATATTATTTAGACTAATCCAG
ATTTGCTTTCTATGAAAATCTAATGTCTGGATTATCTTCCTTTTCTCATGGCCTAAGAAATAAGGATCAATAAGGAATGATTTGAATGTA
ATTTTGTGAATGTGTGGAAAATATAAAGCAGGGATTTAGCCTTAATAAAGGTAACCTTCTGACATCTGTTGTTAATCCCCCTTTGTACTC
TTTTCCTGTATCTGCACTGTTATTTTGAGATGTCATACTGTACACTGTATTGTAAAAATAAAAAGTAAAATTATATTTCAAATTTTAAAA

>71751_71751_2_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000390683_MPP5_chr14_67770238_ENST00000555925_length(amino acids)=606AA_BP=252
MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSADFSPAFLSTTLSAL
DEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKVHLY
RELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPSDMHGTLTFVLIPSQQIK
PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEP
EKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRR
DQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALL

--------------------------------------------------------------
>71751_71751_3_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000471583_MPP5_chr14_67770238_ENST00000261681_length(transcript)=4732nt_BP=804nt
CTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAG
CTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTG
AGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGG
TCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACA
GAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTA
GAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTT
AACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCT
TTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTT
CAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCATCTGAT
ATGCATGGTACTTTGACTTTTGTCCTGATTCCCAGTCAACAGATCAAGCCGCCTCCTGCCAAGGAAACAGTAATCCATGTAAAAGCTCAT
TTTGACTATGACCCCTCAGATGACCCTTATGTTCCATGTCGAGAGTTAGGTCTGTCTTTTCAAAAAGGTGATATACTTCATGTGATCAGT
CAAGAAGATCCAAACTGGTGGCAGGCCTACAGGGAAGGGGACGAAGATAATCAACCTCTAGCCGGGCTTGTTCCAGGGAAAAGCTTTCAG
CAGCAAAGGGAAGCCATGAAACAAACCATAGAAGAAGATAAGGAGCCAGAAAAATCAGGAAAACTGTGGTGTGCAAAGAAGAATAAAAAG
AAGAGGAAAAAGGTTTTATATAATGCCAATAAAAATGATGATTATGACAACGAGGAGATCTTAACCTATGAGGAAATGTCACTTTATCAT
CAGCCAGCAAATAGGAAGAGACCTATCATCTTGATTGGTCCACAGAACTGTGGCCAGAATGAATTGCGTCAGAGGCTCATGAACAAAGAA
AAGGACCGCTTTGCATCTGCAGTTCCTCATACAACCCGGAGTAGGCGAGACCAAGAAGTAGCCGGTAGAGATTACCACTTTGTTTCGCGG
CAAGCATTCGAGGCAGACATAGCAGCTGGAAAGTTCATTGAGCATGGTGAATTTGAGAAGAATTTGTATGGAACTAGCATAGATTCTGTA
CGGCAAGTGATCAACTCTGGCAAAATATGTCTTTTAAGTCTTCGTACACAGTCATTGAAGACTCTCCGGAATTCAGATTTGAAACCATAT
ATTATCTTCATTGCACCCCCTTCACAAGAAAGACTTCGGGCATTATTGGCCAAAGAAGGCAAGAATCCAAAGCCTGAAGAGTTGAGAGAA
ATCATTGAGAAGACAAGAGAGATGGAGCAGAACAATGGCCACTACTTTGATACGGCAATTGTGAATTCCGATCTTGATAAAGCCTATCAG
GAATTGCTTAGGTTAATTAACAAACTTGATACTGAACCTCAGTGGGTACCATCCACTTGGCTGAGGTGAAAGAAACATCCATTCTGTGGC
ATGTTGGACTTGATCTGGCAAAAACTGCCAATAGGAGGACTGCCCGACACTGCAGCAAGATTGAGGATAAGATGGAAGGCAGCAGTATAA
GCTGTAGATCTGTTCTTAGATCTCTTGAATTAGTGAGACGACAGTTCCCTTAGGCAGTTTGTGCATGGCATCCTTTATTCTCTATACATG
GCTTTAGCGGTTCTTGCCTCATTTTGGGATTCTAAATGGAAGCTTTCAACAGAGCATTCCATTTTGTCCTGTTAAAACCTTTTGTTTTCA
CCTAAACCCTTTCTGCTTAGTTGTATCTCTGTGAAAAACTTGTATACACAAGCGTCCATGTCTCACACAAATATTGATGTGATTATTCTT
AAGTGTTAAATCATTAACACTTAAATGACTTCATTGGGAATATTGAGCAGAGGGACTGTGCTTCTATGCACTGGGCAAGGCAGTATTTGC
TTAGGAAACTAATTTAGTCATCAGAGATACTTTCCTAAAAAGGAAAAATAAAAAACAAAATGGTGCCACTTTGGGTTGAAGCTACTTTGT
TAGGCTTGAATTCATTTATATGTCTTTTGATTCTTAAAAAAACAAAAAACATTCCATTAGAAGCACCAGTTTTTTTGCTCAGACTTTGTG
GATCAGACTCTACACTCAACACACTCTAATCTACTTAAAGGTATACAAAATATGCTGATCTTTTTTAAATTATGATTTCCTGAATTTTTT
TCTTAAGTCGTCTCAACTGATTTACTCACTTAGCTTCCCTTCCCTCATCAGCATAGTATAATAGAATGTATGTTACATTTTTATGAATGG
CAGGTGTTCATTATAATCTGTATTGACTTAAAAAGTTTCTTCCTCATGATGCTAATAGTTTTTTGTATACATGGGAGGATAGCACATTTG
ACAGTTTTTGCATTTTTATGTATGAGCACAGTATCCTATGACTGTGCTACGTATATATAGGTAATAAACTGGAATTCTGTTGATGAATAT
AGCTGCTGTACTGTATATTAATATTTAATAGATCAACAAATGGTCATTGAAAACACTTGTTTAGCATTAGAATAAAATTATATATGTCCT
TGGGAAATATTATGACAGTTGACTTTAAGATCAAAAGGAAGGGAAGACCTGAAAGTCATTTGAACATTTTAGGAAAAGAATATTGGAGAG
AAAAAGGTATTAAATATATAGAAATAGGTTTTTAACCTAACAAGGTCTGCCTCTTATGACGAGAATGCAACAGCTTGGTAAATCATAAAA
GAAACATTTAAGCTAATAGGATTTTCGTACTGTCTCTATAGCTGTAGCTTTAAAATTCAACGTATATAATTGGCATGGAAACTTAATTTG
CAGTCTTTTCAAGCCTTTAGGATAGTGTGATGTGTAACAAACAACCTCAAATGTGAATGCCTTGATTTTATTTTTATGGTGACTTTAGCT
ACAGCATTTCCTATACCCAGAGCTAAACACTGGAATAATACTGACATCATTTAATTTAACATAAGCAATTATGTTTAAGGAGTAATTTGT
GTCATGTACATATTTGATTGATTTTTTTTCTTCTACATAATTTTATTTGAACAAATGTAGACAGTTTATATGTCGCCTTTTTCTGTTCAA
ATTTGCATGGCCTATTAAGTTGGCTGGAGAGTGTTTTATGTGGAAATATTTTCAAGATAATGTTCCTTAGGAAGAAAATAACATTCTTGG
GTTGAGGGAAGGAATGCCATACACTACTGTCTCTTCAGATCTGAAATACTCCAGTTTAGAGCCAGGAAATTTCACAGGTCACACCGATTT
TTAGCATTAAAAACTAAGGAATATACTTAGCACTTACTTAATCTTTTCAGTTTTCCAGTTTACGTCTCAGGAATGAAGTGTAGTCTATGG
TTGACAATGGAGTTTTGTGATCCTGCTTATTGTAACTGACAACTGTTTTCAACTCCAAGAGCTAAACTATTGGCAGTTCATGTTAAGTTA
GAGTGAGGGTGTAGGTAGTGTCAGTGAGTGGCTCTTGTGCCTGCTGTAGACATTAGGCCTGCACTAGGGCCATGTGCTGTCAAGATTCAG
GAACATGGCTTTAACAAGCAGATCTTGTATCAAGGCAGAGGTGATGCCATGCCATACTTTTAGGAAGTCTGAGATGATAAATATTTCAAG
GTCAGTGAAGTCTATCAATCATTCTCCCCTTCCTCATCAGCAATGGTAGATAGAAATGTCCTAAACTTTTCTAAATCCTAGTGATGAGGA
TGTGCTGATATTCAACATAGTCCTTAAAGTGAAAACTGAGTTGTTGCTGACCTCCACAAAAGAATATGGAAAAAAGCCTTGCTGTACACC
TAGTTGTACAGCCACTCTGGCCAATTCCATTTCCTGTCCCTCTGTGGTTCTGACTGGAGACCCCAGTGTGGGGGAGGTCTTACCATTTAA
TATAGAAATGATATCAATAACTAATGCTATGTACTTGGAAAATCCAAATAAGGAAGTTTTAGGTTGGTGCATAACTTTGTTTCTCAAATT
TTCGTTGTCAGAACAAATGGAAGGAGAATATTATTTAGACTAATCCAGATTTGCTTTCTATGAAAATCTAATGTCTGGATTATCTTCCTT
TTCTCATGGCCTAAGAAATAAGGATCAATAAGGAATGATTTGAATGTAATTTTGTGAATGTGTGGAAAATATAAAGCAGGGATTTAGCCT
TAATAAAGGTAACCTTCTGACATCTGTTGTTAATCCCCCTTTGTACTCTTTTCCTGTATCTGCACTGTTATTTTGAGATGTCATACTGTA

>71751_71751_3_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000471583_MPP5_chr14_67770238_ENST00000261681_length(amino acids)=622AA_BP=268
LCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPSD
MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ
QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKE
KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY

--------------------------------------------------------------
>71751_71751_4_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000471583_MPP5_chr14_67770238_ENST00000555925_length(transcript)=4732nt_BP=804nt
CTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAG
CTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTG
AGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGG
TCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACA
GAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTA
GAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTT
AACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCT
TTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTT
CAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCATCTGAT
ATGCATGGTACTTTGACTTTTGTCCTGATTCCCAGTCAACAGATCAAGCCGCCTCCTGCCAAGGAAACAGTAATCCATGTAAAAGCTCAT
TTTGACTATGACCCCTCAGATGACCCTTATGTTCCATGTCGAGAGTTAGGTCTGTCTTTTCAAAAAGGTGATATACTTCATGTGATCAGT
CAAGAAGATCCAAACTGGTGGCAGGCCTACAGGGAAGGGGACGAAGATAATCAACCTCTAGCCGGGCTTGTTCCAGGGAAAAGCTTTCAG
CAGCAAAGGGAAGCCATGAAACAAACCATAGAAGAAGATAAGGAGCCAGAAAAATCAGGAAAACTGTGGTGTGCAAAGAAGAATAAAAAG
AAGAGGAAAAAGGTTTTATATAATGCCAATAAAAATGATGATTATGACAACGAGGAGATCTTAACCTATGAGGAAATGTCACTTTATCAT
CAGCCAGCAAATAGGAAGAGACCTATCATCTTGATTGGTCCACAGAACTGTGGCCAGAATGAATTGCGTCAGAGGCTCATGAACAAAGAA
AAGGACCGCTTTGCATCTGCAGTTCCTCATACAACCCGGAGTAGGCGAGACCAAGAAGTAGCCGGTAGAGATTACCACTTTGTTTCGCGG
CAAGCATTCGAGGCAGACATAGCAGCTGGAAAGTTCATTGAGCATGGTGAATTTGAGAAGAATTTGTATGGAACTAGCATAGATTCTGTA
CGGCAAGTGATCAACTCTGGCAAAATATGTCTTTTAAGTCTTCGTACACAGTCATTGAAGACTCTCCGGAATTCAGATTTGAAACCATAT
ATTATCTTCATTGCACCCCCTTCACAAGAAAGACTTCGGGCATTATTGGCCAAAGAAGGCAAGAATCCAAAGCCTGAAGAGTTGAGAGAA
ATCATTGAGAAGACAAGAGAGATGGAGCAGAACAATGGCCACTACTTTGATACGGCAATTGTGAATTCCGATCTTGATAAAGCCTATCAG
GAATTGCTTAGGTTAATTAACAAACTTGATACTGAACCTCAGTGGGTACCATCCACTTGGCTGAGGTGAAAGAAACATCCATTCTGTGGC
ATGTTGGACTTGATCTGGCAAAAACTGCCAATAGGAGGACTGCCCGACACTGCAGCAAGATTGAGGATAAGATGGAAGGCAGCAGTATAA
GCTGTAGATCTGTTCTTAGATCTCTTGAATTAGTGAGACGACAGTTCCCTTAGGCAGTTTGTGCATGGCATCCTTTATTCTCTATACATG
GCTTTAGCGGTTCTTGCCTCATTTTGGGATTCTAAATGGAAGCTTTCAACAGAGCATTCCATTTTGTCCTGTTAAAACCTTTTGTTTTCA
CCTAAACCCTTTCTGCTTAGTTGTATCTCTGTGAAAAACTTGTATACACAAGCGTCCATGTCTCACACAAATATTGATGTGATTATTCTT
AAGTGTTAAATCATTAACACTTAAATGACTTCATTGGGAATATTGAGCAGAGGGACTGTGCTTCTATGCACTGGGCAAGGCAGTATTTGC
TTAGGAAACTAATTTAGTCATCAGAGATACTTTCCTAAAAAGGAAAAATAAAAAACAAAATGGTGCCACTTTGGGTTGAAGCTACTTTGT
TAGGCTTGAATTCATTTATATGTCTTTTGATTCTTAAAAAAACAAAAAACATTCCATTAGAAGCACCAGTTTTTTTGCTCAGACTTTGTG
GATCAGACTCTACACTCAACACACTCTAATCTACTTAAAGGTATACAAAATATGCTGATCTTTTTTAAATTATGATTTCCTGAATTTTTT
TCTTAAGTCGTCTCAACTGATTTACTCACTTAGCTTCCCTTCCCTCATCAGCATAGTATAATAGAATGTATGTTACATTTTTATGAATGG
CAGGTGTTCATTATAATCTGTATTGACTTAAAAAGTTTCTTCCTCATGATGCTAATAGTTTTTTGTATACATGGGAGGATAGCACATTTG
ACAGTTTTTGCATTTTTATGTATGAGCACAGTATCCTATGACTGTGCTACGTATATATAGGTAATAAACTGGAATTCTGTTGATGAATAT
AGCTGCTGTACTGTATATTAATATTTAATAGATCAACAAATGGTCATTGAAAACACTTGTTTAGCATTAGAATAAAATTATATATGTCCT
TGGGAAATATTATGACAGTTGACTTTAAGATCAAAAGGAAGGGAAGACCTGAAAGTCATTTGAACATTTTAGGAAAAGAATATTGGAGAG
AAAAAGGTATTAAATATATAGAAATAGGTTTTTAACCTAACAAGGTCTGCCTCTTATGACGAGAATGCAACAGCTTGGTAAATCATAAAA
GAAACATTTAAGCTAATAGGATTTTCGTACTGTCTCTATAGCTGTAGCTTTAAAATTCAACGTATATAATTGGCATGGAAACTTAATTTG
CAGTCTTTTCAAGCCTTTAGGATAGTGTGATGTGTAACAAACAACCTCAAATGTGAATGCCTTGATTTTATTTTTATGGTGACTTTAGCT
ACAGCATTTCCTATACCCAGAGCTAAACACTGGAATAATACTGACATCATTTAATTTAACATAAGCAATTATGTTTAAGGAGTAATTTGT
GTCATGTACATATTTGATTGATTTTTTTTCTTCTACATAATTTTATTTGAACAAATGTAGACAGTTTATATGTCGCCTTTTTCTGTTCAA
ATTTGCATGGCCTATTAAGTTGGCTGGAGAGTGTTTTATGTGGAAATATTTTCAAGATAATGTTCCTTAGGAAGAAAATAACATTCTTGG
GTTGAGGGAAGGAATGCCATACACTACTGTCTCTTCAGATCTGAAATACTCCAGTTTAGAGCCAGGAAATTTCACAGGTCACACCGATTT
TTAGCATTAAAAACTAAGGAATATACTTAGCACTTACTTAATCTTTTCAGTTTTCCAGTTTACGTCTCAGGAATGAAGTGTAGTCTATGG
TTGACAATGGAGTTTTGTGATCCTGCTTATTGTAACTGACAACTGTTTTCAACTCCAAGAGCTAAACTATTGGCAGTTCATGTTAAGTTA
GAGTGAGGGTGTAGGTAGTGTCAGTGAGTGGCTCTTGTGCCTGCTGTAGACATTAGGCCTGCACTAGGGCCATGTGCTGTCAAGATTCAG
GAACATGGCTTTAACAAGCAGATCTTGTATCAAGGCAGAGGTGATGCCATGCCATACTTTTAGGAAGTCTGAGATGATAAATATTTCAAG
GTCAGTGAAGTCTATCAATCATTCTCCCCTTCCTCATCAGCAATGGTAGATAGAAATGTCCTAAACTTTTCTAAATCCTAGTGATGAGGA
TGTGCTGATATTCAACATAGTCCTTAAAGTGAAAACTGAGTTGTTGCTGACCTCCACAAAAGAATATGGAAAAAAGCCTTGCTGTACACC
TAGTTGTACAGCCACTCTGGCCAATTCCATTTCCTGTCCCTCTGTGGTTCTGACTGGAGACCCCAGTGTGGGGGAGGTCTTACCATTTAA
TATAGAAATGATATCAATAACTAATGCTATGTACTTGGAAAATCCAAATAAGGAAGTTTTAGGTTGGTGCATAACTTTGTTTCTCAAATT
TTCGTTGTCAGAACAAATGGAAGGAGAATATTATTTAGACTAATCCAGATTTGCTTTCTATGAAAATCTAATGTCTGGATTATCTTCCTT
TTCTCATGGCCTAAGAAATAAGGATCAATAAGGAATGATTTGAATGTAATTTTGTGAATGTGTGGAAAATATAAAGCAGGGATTTAGCCT
TAATAAAGGTAACCTTCTGACATCTGTTGTTAATCCCCCTTTGTACTCTTTTCCTGTATCTGCACTGTTATTTTGAGATGTCATACTGTA

>71751_71751_4_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000471583_MPP5_chr14_67770238_ENST00000555925_length(amino acids)=622AA_BP=268
LCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPSD
MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ
QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKE
KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY

--------------------------------------------------------------
>71751_71751_5_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000487270_MPP5_chr14_67770238_ENST00000261681_length(transcript)=4732nt_BP=804nt
CTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAG
CTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTG
AGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGG
TCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACA
GAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTA
GAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTT
AACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCT
TTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTT
CAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCATCTGAT
ATGCATGGTACTTTGACTTTTGTCCTGATTCCCAGTCAACAGATCAAGCCGCCTCCTGCCAAGGAAACAGTAATCCATGTAAAAGCTCAT
TTTGACTATGACCCCTCAGATGACCCTTATGTTCCATGTCGAGAGTTAGGTCTGTCTTTTCAAAAAGGTGATATACTTCATGTGATCAGT
CAAGAAGATCCAAACTGGTGGCAGGCCTACAGGGAAGGGGACGAAGATAATCAACCTCTAGCCGGGCTTGTTCCAGGGAAAAGCTTTCAG
CAGCAAAGGGAAGCCATGAAACAAACCATAGAAGAAGATAAGGAGCCAGAAAAATCAGGAAAACTGTGGTGTGCAAAGAAGAATAAAAAG
AAGAGGAAAAAGGTTTTATATAATGCCAATAAAAATGATGATTATGACAACGAGGAGATCTTAACCTATGAGGAAATGTCACTTTATCAT
CAGCCAGCAAATAGGAAGAGACCTATCATCTTGATTGGTCCACAGAACTGTGGCCAGAATGAATTGCGTCAGAGGCTCATGAACAAAGAA
AAGGACCGCTTTGCATCTGCAGTTCCTCATACAACCCGGAGTAGGCGAGACCAAGAAGTAGCCGGTAGAGATTACCACTTTGTTTCGCGG
CAAGCATTCGAGGCAGACATAGCAGCTGGAAAGTTCATTGAGCATGGTGAATTTGAGAAGAATTTGTATGGAACTAGCATAGATTCTGTA
CGGCAAGTGATCAACTCTGGCAAAATATGTCTTTTAAGTCTTCGTACACAGTCATTGAAGACTCTCCGGAATTCAGATTTGAAACCATAT
ATTATCTTCATTGCACCCCCTTCACAAGAAAGACTTCGGGCATTATTGGCCAAAGAAGGCAAGAATCCAAAGCCTGAAGAGTTGAGAGAA
ATCATTGAGAAGACAAGAGAGATGGAGCAGAACAATGGCCACTACTTTGATACGGCAATTGTGAATTCCGATCTTGATAAAGCCTATCAG
GAATTGCTTAGGTTAATTAACAAACTTGATACTGAACCTCAGTGGGTACCATCCACTTGGCTGAGGTGAAAGAAACATCCATTCTGTGGC
ATGTTGGACTTGATCTGGCAAAAACTGCCAATAGGAGGACTGCCCGACACTGCAGCAAGATTGAGGATAAGATGGAAGGCAGCAGTATAA
GCTGTAGATCTGTTCTTAGATCTCTTGAATTAGTGAGACGACAGTTCCCTTAGGCAGTTTGTGCATGGCATCCTTTATTCTCTATACATG
GCTTTAGCGGTTCTTGCCTCATTTTGGGATTCTAAATGGAAGCTTTCAACAGAGCATTCCATTTTGTCCTGTTAAAACCTTTTGTTTTCA
CCTAAACCCTTTCTGCTTAGTTGTATCTCTGTGAAAAACTTGTATACACAAGCGTCCATGTCTCACACAAATATTGATGTGATTATTCTT
AAGTGTTAAATCATTAACACTTAAATGACTTCATTGGGAATATTGAGCAGAGGGACTGTGCTTCTATGCACTGGGCAAGGCAGTATTTGC
TTAGGAAACTAATTTAGTCATCAGAGATACTTTCCTAAAAAGGAAAAATAAAAAACAAAATGGTGCCACTTTGGGTTGAAGCTACTTTGT
TAGGCTTGAATTCATTTATATGTCTTTTGATTCTTAAAAAAACAAAAAACATTCCATTAGAAGCACCAGTTTTTTTGCTCAGACTTTGTG
GATCAGACTCTACACTCAACACACTCTAATCTACTTAAAGGTATACAAAATATGCTGATCTTTTTTAAATTATGATTTCCTGAATTTTTT
TCTTAAGTCGTCTCAACTGATTTACTCACTTAGCTTCCCTTCCCTCATCAGCATAGTATAATAGAATGTATGTTACATTTTTATGAATGG
CAGGTGTTCATTATAATCTGTATTGACTTAAAAAGTTTCTTCCTCATGATGCTAATAGTTTTTTGTATACATGGGAGGATAGCACATTTG
ACAGTTTTTGCATTTTTATGTATGAGCACAGTATCCTATGACTGTGCTACGTATATATAGGTAATAAACTGGAATTCTGTTGATGAATAT
AGCTGCTGTACTGTATATTAATATTTAATAGATCAACAAATGGTCATTGAAAACACTTGTTTAGCATTAGAATAAAATTATATATGTCCT
TGGGAAATATTATGACAGTTGACTTTAAGATCAAAAGGAAGGGAAGACCTGAAAGTCATTTGAACATTTTAGGAAAAGAATATTGGAGAG
AAAAAGGTATTAAATATATAGAAATAGGTTTTTAACCTAACAAGGTCTGCCTCTTATGACGAGAATGCAACAGCTTGGTAAATCATAAAA
GAAACATTTAAGCTAATAGGATTTTCGTACTGTCTCTATAGCTGTAGCTTTAAAATTCAACGTATATAATTGGCATGGAAACTTAATTTG
CAGTCTTTTCAAGCCTTTAGGATAGTGTGATGTGTAACAAACAACCTCAAATGTGAATGCCTTGATTTTATTTTTATGGTGACTTTAGCT
ACAGCATTTCCTATACCCAGAGCTAAACACTGGAATAATACTGACATCATTTAATTTAACATAAGCAATTATGTTTAAGGAGTAATTTGT
GTCATGTACATATTTGATTGATTTTTTTTCTTCTACATAATTTTATTTGAACAAATGTAGACAGTTTATATGTCGCCTTTTTCTGTTCAA
ATTTGCATGGCCTATTAAGTTGGCTGGAGAGTGTTTTATGTGGAAATATTTTCAAGATAATGTTCCTTAGGAAGAAAATAACATTCTTGG
GTTGAGGGAAGGAATGCCATACACTACTGTCTCTTCAGATCTGAAATACTCCAGTTTAGAGCCAGGAAATTTCACAGGTCACACCGATTT
TTAGCATTAAAAACTAAGGAATATACTTAGCACTTACTTAATCTTTTCAGTTTTCCAGTTTACGTCTCAGGAATGAAGTGTAGTCTATGG
TTGACAATGGAGTTTTGTGATCCTGCTTATTGTAACTGACAACTGTTTTCAACTCCAAGAGCTAAACTATTGGCAGTTCATGTTAAGTTA
GAGTGAGGGTGTAGGTAGTGTCAGTGAGTGGCTCTTGTGCCTGCTGTAGACATTAGGCCTGCACTAGGGCCATGTGCTGTCAAGATTCAG
GAACATGGCTTTAACAAGCAGATCTTGTATCAAGGCAGAGGTGATGCCATGCCATACTTTTAGGAAGTCTGAGATGATAAATATTTCAAG
GTCAGTGAAGTCTATCAATCATTCTCCCCTTCCTCATCAGCAATGGTAGATAGAAATGTCCTAAACTTTTCTAAATCCTAGTGATGAGGA
TGTGCTGATATTCAACATAGTCCTTAAAGTGAAAACTGAGTTGTTGCTGACCTCCACAAAAGAATATGGAAAAAAGCCTTGCTGTACACC
TAGTTGTACAGCCACTCTGGCCAATTCCATTTCCTGTCCCTCTGTGGTTCTGACTGGAGACCCCAGTGTGGGGGAGGTCTTACCATTTAA
TATAGAAATGATATCAATAACTAATGCTATGTACTTGGAAAATCCAAATAAGGAAGTTTTAGGTTGGTGCATAACTTTGTTTCTCAAATT
TTCGTTGTCAGAACAAATGGAAGGAGAATATTATTTAGACTAATCCAGATTTGCTTTCTATGAAAATCTAATGTCTGGATTATCTTCCTT
TTCTCATGGCCTAAGAAATAAGGATCAATAAGGAATGATTTGAATGTAATTTTGTGAATGTGTGGAAAATATAAAGCAGGGATTTAGCCT
TAATAAAGGTAACCTTCTGACATCTGTTGTTAATCCCCCTTTGTACTCTTTTCCTGTATCTGCACTGTTATTTTGAGATGTCATACTGTA

>71751_71751_5_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000487270_MPP5_chr14_67770238_ENST00000261681_length(amino acids)=622AA_BP=268
LCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPSD
MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ
QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKE
KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY

--------------------------------------------------------------
>71751_71751_6_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000487270_MPP5_chr14_67770238_ENST00000555925_length(transcript)=4732nt_BP=804nt
CTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAG
CTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTG
AGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGG
TCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACA
GAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTA
GAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTT
AACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCT
TTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTT
CAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCATCTGAT
ATGCATGGTACTTTGACTTTTGTCCTGATTCCCAGTCAACAGATCAAGCCGCCTCCTGCCAAGGAAACAGTAATCCATGTAAAAGCTCAT
TTTGACTATGACCCCTCAGATGACCCTTATGTTCCATGTCGAGAGTTAGGTCTGTCTTTTCAAAAAGGTGATATACTTCATGTGATCAGT
CAAGAAGATCCAAACTGGTGGCAGGCCTACAGGGAAGGGGACGAAGATAATCAACCTCTAGCCGGGCTTGTTCCAGGGAAAAGCTTTCAG
CAGCAAAGGGAAGCCATGAAACAAACCATAGAAGAAGATAAGGAGCCAGAAAAATCAGGAAAACTGTGGTGTGCAAAGAAGAATAAAAAG
AAGAGGAAAAAGGTTTTATATAATGCCAATAAAAATGATGATTATGACAACGAGGAGATCTTAACCTATGAGGAAATGTCACTTTATCAT
CAGCCAGCAAATAGGAAGAGACCTATCATCTTGATTGGTCCACAGAACTGTGGCCAGAATGAATTGCGTCAGAGGCTCATGAACAAAGAA
AAGGACCGCTTTGCATCTGCAGTTCCTCATACAACCCGGAGTAGGCGAGACCAAGAAGTAGCCGGTAGAGATTACCACTTTGTTTCGCGG
CAAGCATTCGAGGCAGACATAGCAGCTGGAAAGTTCATTGAGCATGGTGAATTTGAGAAGAATTTGTATGGAACTAGCATAGATTCTGTA
CGGCAAGTGATCAACTCTGGCAAAATATGTCTTTTAAGTCTTCGTACACAGTCATTGAAGACTCTCCGGAATTCAGATTTGAAACCATAT
ATTATCTTCATTGCACCCCCTTCACAAGAAAGACTTCGGGCATTATTGGCCAAAGAAGGCAAGAATCCAAAGCCTGAAGAGTTGAGAGAA
ATCATTGAGAAGACAAGAGAGATGGAGCAGAACAATGGCCACTACTTTGATACGGCAATTGTGAATTCCGATCTTGATAAAGCCTATCAG
GAATTGCTTAGGTTAATTAACAAACTTGATACTGAACCTCAGTGGGTACCATCCACTTGGCTGAGGTGAAAGAAACATCCATTCTGTGGC
ATGTTGGACTTGATCTGGCAAAAACTGCCAATAGGAGGACTGCCCGACACTGCAGCAAGATTGAGGATAAGATGGAAGGCAGCAGTATAA
GCTGTAGATCTGTTCTTAGATCTCTTGAATTAGTGAGACGACAGTTCCCTTAGGCAGTTTGTGCATGGCATCCTTTATTCTCTATACATG
GCTTTAGCGGTTCTTGCCTCATTTTGGGATTCTAAATGGAAGCTTTCAACAGAGCATTCCATTTTGTCCTGTTAAAACCTTTTGTTTTCA
CCTAAACCCTTTCTGCTTAGTTGTATCTCTGTGAAAAACTTGTATACACAAGCGTCCATGTCTCACACAAATATTGATGTGATTATTCTT
AAGTGTTAAATCATTAACACTTAAATGACTTCATTGGGAATATTGAGCAGAGGGACTGTGCTTCTATGCACTGGGCAAGGCAGTATTTGC
TTAGGAAACTAATTTAGTCATCAGAGATACTTTCCTAAAAAGGAAAAATAAAAAACAAAATGGTGCCACTTTGGGTTGAAGCTACTTTGT
TAGGCTTGAATTCATTTATATGTCTTTTGATTCTTAAAAAAACAAAAAACATTCCATTAGAAGCACCAGTTTTTTTGCTCAGACTTTGTG
GATCAGACTCTACACTCAACACACTCTAATCTACTTAAAGGTATACAAAATATGCTGATCTTTTTTAAATTATGATTTCCTGAATTTTTT
TCTTAAGTCGTCTCAACTGATTTACTCACTTAGCTTCCCTTCCCTCATCAGCATAGTATAATAGAATGTATGTTACATTTTTATGAATGG
CAGGTGTTCATTATAATCTGTATTGACTTAAAAAGTTTCTTCCTCATGATGCTAATAGTTTTTTGTATACATGGGAGGATAGCACATTTG
ACAGTTTTTGCATTTTTATGTATGAGCACAGTATCCTATGACTGTGCTACGTATATATAGGTAATAAACTGGAATTCTGTTGATGAATAT
AGCTGCTGTACTGTATATTAATATTTAATAGATCAACAAATGGTCATTGAAAACACTTGTTTAGCATTAGAATAAAATTATATATGTCCT
TGGGAAATATTATGACAGTTGACTTTAAGATCAAAAGGAAGGGAAGACCTGAAAGTCATTTGAACATTTTAGGAAAAGAATATTGGAGAG
AAAAAGGTATTAAATATATAGAAATAGGTTTTTAACCTAACAAGGTCTGCCTCTTATGACGAGAATGCAACAGCTTGGTAAATCATAAAA
GAAACATTTAAGCTAATAGGATTTTCGTACTGTCTCTATAGCTGTAGCTTTAAAATTCAACGTATATAATTGGCATGGAAACTTAATTTG
CAGTCTTTTCAAGCCTTTAGGATAGTGTGATGTGTAACAAACAACCTCAAATGTGAATGCCTTGATTTTATTTTTATGGTGACTTTAGCT
ACAGCATTTCCTATACCCAGAGCTAAACACTGGAATAATACTGACATCATTTAATTTAACATAAGCAATTATGTTTAAGGAGTAATTTGT
GTCATGTACATATTTGATTGATTTTTTTTCTTCTACATAATTTTATTTGAACAAATGTAGACAGTTTATATGTCGCCTTTTTCTGTTCAA
ATTTGCATGGCCTATTAAGTTGGCTGGAGAGTGTTTTATGTGGAAATATTTTCAAGATAATGTTCCTTAGGAAGAAAATAACATTCTTGG
GTTGAGGGAAGGAATGCCATACACTACTGTCTCTTCAGATCTGAAATACTCCAGTTTAGAGCCAGGAAATTTCACAGGTCACACCGATTT
TTAGCATTAAAAACTAAGGAATATACTTAGCACTTACTTAATCTTTTCAGTTTTCCAGTTTACGTCTCAGGAATGAAGTGTAGTCTATGG
TTGACAATGGAGTTTTGTGATCCTGCTTATTGTAACTGACAACTGTTTTCAACTCCAAGAGCTAAACTATTGGCAGTTCATGTTAAGTTA
GAGTGAGGGTGTAGGTAGTGTCAGTGAGTGGCTCTTGTGCCTGCTGTAGACATTAGGCCTGCACTAGGGCCATGTGCTGTCAAGATTCAG
GAACATGGCTTTAACAAGCAGATCTTGTATCAAGGCAGAGGTGATGCCATGCCATACTTTTAGGAAGTCTGAGATGATAAATATTTCAAG
GTCAGTGAAGTCTATCAATCATTCTCCCCTTCCTCATCAGCAATGGTAGATAGAAATGTCCTAAACTTTTCTAAATCCTAGTGATGAGGA
TGTGCTGATATTCAACATAGTCCTTAAAGTGAAAACTGAGTTGTTGCTGACCTCCACAAAAGAATATGGAAAAAAGCCTTGCTGTACACC
TAGTTGTACAGCCACTCTGGCCAATTCCATTTCCTGTCCCTCTGTGGTTCTGACTGGAGACCCCAGTGTGGGGGAGGTCTTACCATTTAA
TATAGAAATGATATCAATAACTAATGCTATGTACTTGGAAAATCCAAATAAGGAAGTTTTAGGTTGGTGCATAACTTTGTTTCTCAAATT
TTCGTTGTCAGAACAAATGGAAGGAGAATATTATTTAGACTAATCCAGATTTGCTTTCTATGAAAATCTAATGTCTGGATTATCTTCCTT
TTCTCATGGCCTAAGAAATAAGGATCAATAAGGAATGATTTGAATGTAATTTTGTGAATGTGTGGAAAATATAAAGCAGGGATTTAGCCT
TAATAAAGGTAACCTTCTGACATCTGTTGTTAATCCCCCTTTGTACTCTTTTCCTGTATCTGCACTGTTATTTTGAGATGTCATACTGTA

>71751_71751_6_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000487270_MPP5_chr14_67770238_ENST00000555925_length(amino acids)=622AA_BP=268
LCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPSD
MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ
QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKE
KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY

--------------------------------------------------------------
>71751_71751_7_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000487861_MPP5_chr14_67770238_ENST00000261681_length(transcript)=4761nt_BP=833nt
GTTGCTTTGCGGCGTTTTCCGCGGGGAAACTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGA
AACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCC
CACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGC
AAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGC
ATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGG
CTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAA
TAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCT
GTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTG
TGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATT
TGGCTGAGGAGTTTTCAATCCCATCTGATATGCATGGTACTTTGACTTTTGTCCTGATTCCCAGTCAACAGATCAAGCCGCCTCCTGCCA
AGGAAACAGTAATCCATGTAAAAGCTCATTTTGACTATGACCCCTCAGATGACCCTTATGTTCCATGTCGAGAGTTAGGTCTGTCTTTTC
AAAAAGGTGATATACTTCATGTGATCAGTCAAGAAGATCCAAACTGGTGGCAGGCCTACAGGGAAGGGGACGAAGATAATCAACCTCTAG
CCGGGCTTGTTCCAGGGAAAAGCTTTCAGCAGCAAAGGGAAGCCATGAAACAAACCATAGAAGAAGATAAGGAGCCAGAAAAATCAGGAA
AACTGTGGTGTGCAAAGAAGAATAAAAAGAAGAGGAAAAAGGTTTTATATAATGCCAATAAAAATGATGATTATGACAACGAGGAGATCT
TAACCTATGAGGAAATGTCACTTTATCATCAGCCAGCAAATAGGAAGAGACCTATCATCTTGATTGGTCCACAGAACTGTGGCCAGAATG
AATTGCGTCAGAGGCTCATGAACAAAGAAAAGGACCGCTTTGCATCTGCAGTTCCTCATACAACCCGGAGTAGGCGAGACCAAGAAGTAG
CCGGTAGAGATTACCACTTTGTTTCGCGGCAAGCATTCGAGGCAGACATAGCAGCTGGAAAGTTCATTGAGCATGGTGAATTTGAGAAGA
ATTTGTATGGAACTAGCATAGATTCTGTACGGCAAGTGATCAACTCTGGCAAAATATGTCTTTTAAGTCTTCGTACACAGTCATTGAAGA
CTCTCCGGAATTCAGATTTGAAACCATATATTATCTTCATTGCACCCCCTTCACAAGAAAGACTTCGGGCATTATTGGCCAAAGAAGGCA
AGAATCCAAAGCCTGAAGAGTTGAGAGAAATCATTGAGAAGACAAGAGAGATGGAGCAGAACAATGGCCACTACTTTGATACGGCAATTG
TGAATTCCGATCTTGATAAAGCCTATCAGGAATTGCTTAGGTTAATTAACAAACTTGATACTGAACCTCAGTGGGTACCATCCACTTGGC
TGAGGTGAAAGAAACATCCATTCTGTGGCATGTTGGACTTGATCTGGCAAAAACTGCCAATAGGAGGACTGCCCGACACTGCAGCAAGAT
TGAGGATAAGATGGAAGGCAGCAGTATAAGCTGTAGATCTGTTCTTAGATCTCTTGAATTAGTGAGACGACAGTTCCCTTAGGCAGTTTG
TGCATGGCATCCTTTATTCTCTATACATGGCTTTAGCGGTTCTTGCCTCATTTTGGGATTCTAAATGGAAGCTTTCAACAGAGCATTCCA
TTTTGTCCTGTTAAAACCTTTTGTTTTCACCTAAACCCTTTCTGCTTAGTTGTATCTCTGTGAAAAACTTGTATACACAAGCGTCCATGT
CTCACACAAATATTGATGTGATTATTCTTAAGTGTTAAATCATTAACACTTAAATGACTTCATTGGGAATATTGAGCAGAGGGACTGTGC
TTCTATGCACTGGGCAAGGCAGTATTTGCTTAGGAAACTAATTTAGTCATCAGAGATACTTTCCTAAAAAGGAAAAATAAAAAACAAAAT
GGTGCCACTTTGGGTTGAAGCTACTTTGTTAGGCTTGAATTCATTTATATGTCTTTTGATTCTTAAAAAAACAAAAAACATTCCATTAGA
AGCACCAGTTTTTTTGCTCAGACTTTGTGGATCAGACTCTACACTCAACACACTCTAATCTACTTAAAGGTATACAAAATATGCTGATCT
TTTTTAAATTATGATTTCCTGAATTTTTTTCTTAAGTCGTCTCAACTGATTTACTCACTTAGCTTCCCTTCCCTCATCAGCATAGTATAA
TAGAATGTATGTTACATTTTTATGAATGGCAGGTGTTCATTATAATCTGTATTGACTTAAAAAGTTTCTTCCTCATGATGCTAATAGTTT
TTTGTATACATGGGAGGATAGCACATTTGACAGTTTTTGCATTTTTATGTATGAGCACAGTATCCTATGACTGTGCTACGTATATATAGG
TAATAAACTGGAATTCTGTTGATGAATATAGCTGCTGTACTGTATATTAATATTTAATAGATCAACAAATGGTCATTGAAAACACTTGTT
TAGCATTAGAATAAAATTATATATGTCCTTGGGAAATATTATGACAGTTGACTTTAAGATCAAAAGGAAGGGAAGACCTGAAAGTCATTT
GAACATTTTAGGAAAAGAATATTGGAGAGAAAAAGGTATTAAATATATAGAAATAGGTTTTTAACCTAACAAGGTCTGCCTCTTATGACG
AGAATGCAACAGCTTGGTAAATCATAAAAGAAACATTTAAGCTAATAGGATTTTCGTACTGTCTCTATAGCTGTAGCTTTAAAATTCAAC
GTATATAATTGGCATGGAAACTTAATTTGCAGTCTTTTCAAGCCTTTAGGATAGTGTGATGTGTAACAAACAACCTCAAATGTGAATGCC
TTGATTTTATTTTTATGGTGACTTTAGCTACAGCATTTCCTATACCCAGAGCTAAACACTGGAATAATACTGACATCATTTAATTTAACA
TAAGCAATTATGTTTAAGGAGTAATTTGTGTCATGTACATATTTGATTGATTTTTTTTCTTCTACATAATTTTATTTGAACAAATGTAGA
CAGTTTATATGTCGCCTTTTTCTGTTCAAATTTGCATGGCCTATTAAGTTGGCTGGAGAGTGTTTTATGTGGAAATATTTTCAAGATAAT
GTTCCTTAGGAAGAAAATAACATTCTTGGGTTGAGGGAAGGAATGCCATACACTACTGTCTCTTCAGATCTGAAATACTCCAGTTTAGAG
CCAGGAAATTTCACAGGTCACACCGATTTTTAGCATTAAAAACTAAGGAATATACTTAGCACTTACTTAATCTTTTCAGTTTTCCAGTTT
ACGTCTCAGGAATGAAGTGTAGTCTATGGTTGACAATGGAGTTTTGTGATCCTGCTTATTGTAACTGACAACTGTTTTCAACTCCAAGAG
CTAAACTATTGGCAGTTCATGTTAAGTTAGAGTGAGGGTGTAGGTAGTGTCAGTGAGTGGCTCTTGTGCCTGCTGTAGACATTAGGCCTG
CACTAGGGCCATGTGCTGTCAAGATTCAGGAACATGGCTTTAACAAGCAGATCTTGTATCAAGGCAGAGGTGATGCCATGCCATACTTTT
AGGAAGTCTGAGATGATAAATATTTCAAGGTCAGTGAAGTCTATCAATCATTCTCCCCTTCCTCATCAGCAATGGTAGATAGAAATGTCC
TAAACTTTTCTAAATCCTAGTGATGAGGATGTGCTGATATTCAACATAGTCCTTAAAGTGAAAACTGAGTTGTTGCTGACCTCCACAAAA
GAATATGGAAAAAAGCCTTGCTGTACACCTAGTTGTACAGCCACTCTGGCCAATTCCATTTCCTGTCCCTCTGTGGTTCTGACTGGAGAC
CCCAGTGTGGGGGAGGTCTTACCATTTAATATAGAAATGATATCAATAACTAATGCTATGTACTTGGAAAATCCAAATAAGGAAGTTTTA
GGTTGGTGCATAACTTTGTTTCTCAAATTTTCGTTGTCAGAACAAATGGAAGGAGAATATTATTTAGACTAATCCAGATTTGCTTTCTAT
GAAAATCTAATGTCTGGATTATCTTCCTTTTCTCATGGCCTAAGAAATAAGGATCAATAAGGAATGATTTGAATGTAATTTTGTGAATGT
GTGGAAAATATAAAGCAGGGATTTAGCCTTAATAAAGGTAACCTTCTGACATCTGTTGTTAATCCCCCTTTGTACTCTTTTCCTGTATCT

>71751_71751_7_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000487861_MPP5_chr14_67770238_ENST00000261681_length(amino acids)=622AA_BP=268
MCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPSD
MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ
QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKE
KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY

--------------------------------------------------------------
>71751_71751_8_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000487861_MPP5_chr14_67770238_ENST00000555925_length(transcript)=4761nt_BP=833nt
GTTGCTTTGCGGCGTTTTCCGCGGGGAAACTGTGTAAAGGGTGGGGAAACTTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGA
AACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGACATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCC
CACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAACTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGC
AAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCATTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGC
ATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGTTGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGG
CTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATTGACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAA
TAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTTTTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCT
GTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCAAAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTG
TGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGAAACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATT
TGGCTGAGGAGTTTTCAATCCCATCTGATATGCATGGTACTTTGACTTTTGTCCTGATTCCCAGTCAACAGATCAAGCCGCCTCCTGCCA
AGGAAACAGTAATCCATGTAAAAGCTCATTTTGACTATGACCCCTCAGATGACCCTTATGTTCCATGTCGAGAGTTAGGTCTGTCTTTTC
AAAAAGGTGATATACTTCATGTGATCAGTCAAGAAGATCCAAACTGGTGGCAGGCCTACAGGGAAGGGGACGAAGATAATCAACCTCTAG
CCGGGCTTGTTCCAGGGAAAAGCTTTCAGCAGCAAAGGGAAGCCATGAAACAAACCATAGAAGAAGATAAGGAGCCAGAAAAATCAGGAA
AACTGTGGTGTGCAAAGAAGAATAAAAAGAAGAGGAAAAAGGTTTTATATAATGCCAATAAAAATGATGATTATGACAACGAGGAGATCT
TAACCTATGAGGAAATGTCACTTTATCATCAGCCAGCAAATAGGAAGAGACCTATCATCTTGATTGGTCCACAGAACTGTGGCCAGAATG
AATTGCGTCAGAGGCTCATGAACAAAGAAAAGGACCGCTTTGCATCTGCAGTTCCTCATACAACCCGGAGTAGGCGAGACCAAGAAGTAG
CCGGTAGAGATTACCACTTTGTTTCGCGGCAAGCATTCGAGGCAGACATAGCAGCTGGAAAGTTCATTGAGCATGGTGAATTTGAGAAGA
ATTTGTATGGAACTAGCATAGATTCTGTACGGCAAGTGATCAACTCTGGCAAAATATGTCTTTTAAGTCTTCGTACACAGTCATTGAAGA
CTCTCCGGAATTCAGATTTGAAACCATATATTATCTTCATTGCACCCCCTTCACAAGAAAGACTTCGGGCATTATTGGCCAAAGAAGGCA
AGAATCCAAAGCCTGAAGAGTTGAGAGAAATCATTGAGAAGACAAGAGAGATGGAGCAGAACAATGGCCACTACTTTGATACGGCAATTG
TGAATTCCGATCTTGATAAAGCCTATCAGGAATTGCTTAGGTTAATTAACAAACTTGATACTGAACCTCAGTGGGTACCATCCACTTGGC
TGAGGTGAAAGAAACATCCATTCTGTGGCATGTTGGACTTGATCTGGCAAAAACTGCCAATAGGAGGACTGCCCGACACTGCAGCAAGAT
TGAGGATAAGATGGAAGGCAGCAGTATAAGCTGTAGATCTGTTCTTAGATCTCTTGAATTAGTGAGACGACAGTTCCCTTAGGCAGTTTG
TGCATGGCATCCTTTATTCTCTATACATGGCTTTAGCGGTTCTTGCCTCATTTTGGGATTCTAAATGGAAGCTTTCAACAGAGCATTCCA
TTTTGTCCTGTTAAAACCTTTTGTTTTCACCTAAACCCTTTCTGCTTAGTTGTATCTCTGTGAAAAACTTGTATACACAAGCGTCCATGT
CTCACACAAATATTGATGTGATTATTCTTAAGTGTTAAATCATTAACACTTAAATGACTTCATTGGGAATATTGAGCAGAGGGACTGTGC
TTCTATGCACTGGGCAAGGCAGTATTTGCTTAGGAAACTAATTTAGTCATCAGAGATACTTTCCTAAAAAGGAAAAATAAAAAACAAAAT
GGTGCCACTTTGGGTTGAAGCTACTTTGTTAGGCTTGAATTCATTTATATGTCTTTTGATTCTTAAAAAAACAAAAAACATTCCATTAGA
AGCACCAGTTTTTTTGCTCAGACTTTGTGGATCAGACTCTACACTCAACACACTCTAATCTACTTAAAGGTATACAAAATATGCTGATCT
TTTTTAAATTATGATTTCCTGAATTTTTTTCTTAAGTCGTCTCAACTGATTTACTCACTTAGCTTCCCTTCCCTCATCAGCATAGTATAA
TAGAATGTATGTTACATTTTTATGAATGGCAGGTGTTCATTATAATCTGTATTGACTTAAAAAGTTTCTTCCTCATGATGCTAATAGTTT
TTTGTATACATGGGAGGATAGCACATTTGACAGTTTTTGCATTTTTATGTATGAGCACAGTATCCTATGACTGTGCTACGTATATATAGG
TAATAAACTGGAATTCTGTTGATGAATATAGCTGCTGTACTGTATATTAATATTTAATAGATCAACAAATGGTCATTGAAAACACTTGTT
TAGCATTAGAATAAAATTATATATGTCCTTGGGAAATATTATGACAGTTGACTTTAAGATCAAAAGGAAGGGAAGACCTGAAAGTCATTT
GAACATTTTAGGAAAAGAATATTGGAGAGAAAAAGGTATTAAATATATAGAAATAGGTTTTTAACCTAACAAGGTCTGCCTCTTATGACG
AGAATGCAACAGCTTGGTAAATCATAAAAGAAACATTTAAGCTAATAGGATTTTCGTACTGTCTCTATAGCTGTAGCTTTAAAATTCAAC
GTATATAATTGGCATGGAAACTTAATTTGCAGTCTTTTCAAGCCTTTAGGATAGTGTGATGTGTAACAAACAACCTCAAATGTGAATGCC
TTGATTTTATTTTTATGGTGACTTTAGCTACAGCATTTCCTATACCCAGAGCTAAACACTGGAATAATACTGACATCATTTAATTTAACA
TAAGCAATTATGTTTAAGGAGTAATTTGTGTCATGTACATATTTGATTGATTTTTTTTCTTCTACATAATTTTATTTGAACAAATGTAGA
CAGTTTATATGTCGCCTTTTTCTGTTCAAATTTGCATGGCCTATTAAGTTGGCTGGAGAGTGTTTTATGTGGAAATATTTTCAAGATAAT
GTTCCTTAGGAAGAAAATAACATTCTTGGGTTGAGGGAAGGAATGCCATACACTACTGTCTCTTCAGATCTGAAATACTCCAGTTTAGAG
CCAGGAAATTTCACAGGTCACACCGATTTTTAGCATTAAAAACTAAGGAATATACTTAGCACTTACTTAATCTTTTCAGTTTTCCAGTTT
ACGTCTCAGGAATGAAGTGTAGTCTATGGTTGACAATGGAGTTTTGTGATCCTGCTTATTGTAACTGACAACTGTTTTCAACTCCAAGAG
CTAAACTATTGGCAGTTCATGTTAAGTTAGAGTGAGGGTGTAGGTAGTGTCAGTGAGTGGCTCTTGTGCCTGCTGTAGACATTAGGCCTG
CACTAGGGCCATGTGCTGTCAAGATTCAGGAACATGGCTTTAACAAGCAGATCTTGTATCAAGGCAGAGGTGATGCCATGCCATACTTTT
AGGAAGTCTGAGATGATAAATATTTCAAGGTCAGTGAAGTCTATCAATCATTCTCCCCTTCCTCATCAGCAATGGTAGATAGAAATGTCC
TAAACTTTTCTAAATCCTAGTGATGAGGATGTGCTGATATTCAACATAGTCCTTAAAGTGAAAACTGAGTTGTTGCTGACCTCCACAAAA
GAATATGGAAAAAAGCCTTGCTGTACACCTAGTTGTACAGCCACTCTGGCCAATTCCATTTCCTGTCCCTCTGTGGTTCTGACTGGAGAC
CCCAGTGTGGGGGAGGTCTTACCATTTAATATAGAAATGATATCAATAACTAATGCTATGTACTTGGAAAATCCAAATAAGGAAGTTTTA
GGTTGGTGCATAACTTTGTTTCTCAAATTTTCGTTGTCAGAACAAATGGAAGGAGAATATTATTTAGACTAATCCAGATTTGCTTTCTAT
GAAAATCTAATGTCTGGATTATCTTCCTTTTCTCATGGCCTAAGAAATAAGGATCAATAAGGAATGATTTGAATGTAATTTTGTGAATGT
GTGGAAAATATAAAGCAGGGATTTAGCCTTAATAAAGGTAACCTTCTGACATCTGTTGTTAATCCCCCTTTGTACTCTTTTCCTGTATCT

>71751_71751_8_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000487861_MPP5_chr14_67770238_ENST00000555925_length(amino acids)=622AA_BP=268
MCKGWGNLKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQR
SADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYF
NTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPSD
MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ
QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKE
KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY

--------------------------------------------------------------
>71751_71751_9_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000488612_MPP5_chr14_67770238_ENST00000261681_length(transcript)=4711nt_BP=783nt
TTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGA
CATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAA
CTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCA
TTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGT
TGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATT
GACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTT
TTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCA
AAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGA
AACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCATCTGATATGCATGGTACTTTGACTTTT
GTCCTGATTCCCAGTCAACAGATCAAGCCGCCTCCTGCCAAGGAAACAGTAATCCATGTAAAAGCTCATTTTGACTATGACCCCTCAGAT
GACCCTTATGTTCCATGTCGAGAGTTAGGTCTGTCTTTTCAAAAAGGTGATATACTTCATGTGATCAGTCAAGAAGATCCAAACTGGTGG
CAGGCCTACAGGGAAGGGGACGAAGATAATCAACCTCTAGCCGGGCTTGTTCCAGGGAAAAGCTTTCAGCAGCAAAGGGAAGCCATGAAA
CAAACCATAGAAGAAGATAAGGAGCCAGAAAAATCAGGAAAACTGTGGTGTGCAAAGAAGAATAAAAAGAAGAGGAAAAAGGTTTTATAT
AATGCCAATAAAAATGATGATTATGACAACGAGGAGATCTTAACCTATGAGGAAATGTCACTTTATCATCAGCCAGCAAATAGGAAGAGA
CCTATCATCTTGATTGGTCCACAGAACTGTGGCCAGAATGAATTGCGTCAGAGGCTCATGAACAAAGAAAAGGACCGCTTTGCATCTGCA
GTTCCTCATACAACCCGGAGTAGGCGAGACCAAGAAGTAGCCGGTAGAGATTACCACTTTGTTTCGCGGCAAGCATTCGAGGCAGACATA
GCAGCTGGAAAGTTCATTGAGCATGGTGAATTTGAGAAGAATTTGTATGGAACTAGCATAGATTCTGTACGGCAAGTGATCAACTCTGGC
AAAATATGTCTTTTAAGTCTTCGTACACAGTCATTGAAGACTCTCCGGAATTCAGATTTGAAACCATATATTATCTTCATTGCACCCCCT
TCACAAGAAAGACTTCGGGCATTATTGGCCAAAGAAGGCAAGAATCCAAAGCCTGAAGAGTTGAGAGAAATCATTGAGAAGACAAGAGAG
ATGGAGCAGAACAATGGCCACTACTTTGATACGGCAATTGTGAATTCCGATCTTGATAAAGCCTATCAGGAATTGCTTAGGTTAATTAAC
AAACTTGATACTGAACCTCAGTGGGTACCATCCACTTGGCTGAGGTGAAAGAAACATCCATTCTGTGGCATGTTGGACTTGATCTGGCAA
AAACTGCCAATAGGAGGACTGCCCGACACTGCAGCAAGATTGAGGATAAGATGGAAGGCAGCAGTATAAGCTGTAGATCTGTTCTTAGAT
CTCTTGAATTAGTGAGACGACAGTTCCCTTAGGCAGTTTGTGCATGGCATCCTTTATTCTCTATACATGGCTTTAGCGGTTCTTGCCTCA
TTTTGGGATTCTAAATGGAAGCTTTCAACAGAGCATTCCATTTTGTCCTGTTAAAACCTTTTGTTTTCACCTAAACCCTTTCTGCTTAGT
TGTATCTCTGTGAAAAACTTGTATACACAAGCGTCCATGTCTCACACAAATATTGATGTGATTATTCTTAAGTGTTAAATCATTAACACT
TAAATGACTTCATTGGGAATATTGAGCAGAGGGACTGTGCTTCTATGCACTGGGCAAGGCAGTATTTGCTTAGGAAACTAATTTAGTCAT
CAGAGATACTTTCCTAAAAAGGAAAAATAAAAAACAAAATGGTGCCACTTTGGGTTGAAGCTACTTTGTTAGGCTTGAATTCATTTATAT
GTCTTTTGATTCTTAAAAAAACAAAAAACATTCCATTAGAAGCACCAGTTTTTTTGCTCAGACTTTGTGGATCAGACTCTACACTCAACA
CACTCTAATCTACTTAAAGGTATACAAAATATGCTGATCTTTTTTAAATTATGATTTCCTGAATTTTTTTCTTAAGTCGTCTCAACTGAT
TTACTCACTTAGCTTCCCTTCCCTCATCAGCATAGTATAATAGAATGTATGTTACATTTTTATGAATGGCAGGTGTTCATTATAATCTGT
ATTGACTTAAAAAGTTTCTTCCTCATGATGCTAATAGTTTTTTGTATACATGGGAGGATAGCACATTTGACAGTTTTTGCATTTTTATGT
ATGAGCACAGTATCCTATGACTGTGCTACGTATATATAGGTAATAAACTGGAATTCTGTTGATGAATATAGCTGCTGTACTGTATATTAA
TATTTAATAGATCAACAAATGGTCATTGAAAACACTTGTTTAGCATTAGAATAAAATTATATATGTCCTTGGGAAATATTATGACAGTTG
ACTTTAAGATCAAAAGGAAGGGAAGACCTGAAAGTCATTTGAACATTTTAGGAAAAGAATATTGGAGAGAAAAAGGTATTAAATATATAG
AAATAGGTTTTTAACCTAACAAGGTCTGCCTCTTATGACGAGAATGCAACAGCTTGGTAAATCATAAAAGAAACATTTAAGCTAATAGGA
TTTTCGTACTGTCTCTATAGCTGTAGCTTTAAAATTCAACGTATATAATTGGCATGGAAACTTAATTTGCAGTCTTTTCAAGCCTTTAGG
ATAGTGTGATGTGTAACAAACAACCTCAAATGTGAATGCCTTGATTTTATTTTTATGGTGACTTTAGCTACAGCATTTCCTATACCCAGA
GCTAAACACTGGAATAATACTGACATCATTTAATTTAACATAAGCAATTATGTTTAAGGAGTAATTTGTGTCATGTACATATTTGATTGA
TTTTTTTTCTTCTACATAATTTTATTTGAACAAATGTAGACAGTTTATATGTCGCCTTTTTCTGTTCAAATTTGCATGGCCTATTAAGTT
GGCTGGAGAGTGTTTTATGTGGAAATATTTTCAAGATAATGTTCCTTAGGAAGAAAATAACATTCTTGGGTTGAGGGAAGGAATGCCATA
CACTACTGTCTCTTCAGATCTGAAATACTCCAGTTTAGAGCCAGGAAATTTCACAGGTCACACCGATTTTTAGCATTAAAAACTAAGGAA
TATACTTAGCACTTACTTAATCTTTTCAGTTTTCCAGTTTACGTCTCAGGAATGAAGTGTAGTCTATGGTTGACAATGGAGTTTTGTGAT
CCTGCTTATTGTAACTGACAACTGTTTTCAACTCCAAGAGCTAAACTATTGGCAGTTCATGTTAAGTTAGAGTGAGGGTGTAGGTAGTGT
CAGTGAGTGGCTCTTGTGCCTGCTGTAGACATTAGGCCTGCACTAGGGCCATGTGCTGTCAAGATTCAGGAACATGGCTTTAACAAGCAG
ATCTTGTATCAAGGCAGAGGTGATGCCATGCCATACTTTTAGGAAGTCTGAGATGATAAATATTTCAAGGTCAGTGAAGTCTATCAATCA
TTCTCCCCTTCCTCATCAGCAATGGTAGATAGAAATGTCCTAAACTTTTCTAAATCCTAGTGATGAGGATGTGCTGATATTCAACATAGT
CCTTAAAGTGAAAACTGAGTTGTTGCTGACCTCCACAAAAGAATATGGAAAAAAGCCTTGCTGTACACCTAGTTGTACAGCCACTCTGGC
CAATTCCATTTCCTGTCCCTCTGTGGTTCTGACTGGAGACCCCAGTGTGGGGGAGGTCTTACCATTTAATATAGAAATGATATCAATAAC
TAATGCTATGTACTTGGAAAATCCAAATAAGGAAGTTTTAGGTTGGTGCATAACTTTGTTTCTCAAATTTTCGTTGTCAGAACAAATGGA
AGGAGAATATTATTTAGACTAATCCAGATTTGCTTTCTATGAAAATCTAATGTCTGGATTATCTTCCTTTTCTCATGGCCTAAGAAATAA
GGATCAATAAGGAATGATTTGAATGTAATTTTGTGAATGTGTGGAAAATATAAAGCAGGGATTTAGCCTTAATAAAGGTAACCTTCTGAC
ATCTGTTGTTAATCCCCCTTTGTACTCTTTTCCTGTATCTGCACTGTTATTTTGAGATGTCATACTGTACACTGTATTGTAAAAATAAAA

>71751_71751_9_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000488612_MPP5_chr14_67770238_ENST00000261681_length(amino acids)=615AA_BP=261
LKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSADFSPA
FLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLL
LTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPSDMHGTLTF
VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASA
VPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP

--------------------------------------------------------------
>71751_71751_10_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000488612_MPP5_chr14_67770238_ENST00000555925_length(transcript)=4711nt_BP=783nt
TTGAAAGTTGGATGCTGCAGACCCGGCATGGGTAGCAAGAAACTAAAACGAGTGGGTTTATCACAAGAGCTGTGTGACCGTCTGAGTAGA
CATCAGATCCTTACCTGTCAGGACTTTTTATGTCTTTCCCCACTGGAGCTTATGAAGGTGACTGGTCTGAGTTATCGAGGTGTCCATGAA
CTTCTATGTATGGTCAGCAGGGCCTGTGCCCCAAAGATGCAAACGGCTTATGGGATAAAAGCACAAAGGTCTGCTGATTTCTCACCAGCA
TTCTTATCTACTACCCTTTCTGCTTTGGACGAAGCCCTGCATGGTGGTGTGGCTTGTGGATCCCTCACAGAGATTACAGGTCCACCAGGT
TGTGGAAAAACTCAGTTTTGTATAATGATGAGCATTTTGGCTACATTACCCACCAACATGGGAGGATTAGAAGGAGCTGTGGTGTACATT
GACACAGAGTCTGCATTTAGTGCTGAAAGACTGGTTGAAATAGCAGAATCCCGTTTTCCCAGATATTTTAACACTGAAGAAAAGTTACTT
TTGACAAGTAGTAAAGTTCATCTTTATCGGGAACTCACCTGTGATGAAGTTCTACAAAGGATTGAATCTTTGGAAGAAGAAATTATCTCA
AAAGGAATTAAACTTGTGATTCTTGACTCTGTTGCTTCTGTGGTCAGAAAGGAGTTTGATGCACAACTTCAAGGCAATCTCAAAGAAAGA
AACAAGTTCTTGGCAAGAGAGGCATCCTCCTTGAAGTATTTGGCTGAGGAGTTTTCAATCCCATCTGATATGCATGGTACTTTGACTTTT
GTCCTGATTCCCAGTCAACAGATCAAGCCGCCTCCTGCCAAGGAAACAGTAATCCATGTAAAAGCTCATTTTGACTATGACCCCTCAGAT
GACCCTTATGTTCCATGTCGAGAGTTAGGTCTGTCTTTTCAAAAAGGTGATATACTTCATGTGATCAGTCAAGAAGATCCAAACTGGTGG
CAGGCCTACAGGGAAGGGGACGAAGATAATCAACCTCTAGCCGGGCTTGTTCCAGGGAAAAGCTTTCAGCAGCAAAGGGAAGCCATGAAA
CAAACCATAGAAGAAGATAAGGAGCCAGAAAAATCAGGAAAACTGTGGTGTGCAAAGAAGAATAAAAAGAAGAGGAAAAAGGTTTTATAT
AATGCCAATAAAAATGATGATTATGACAACGAGGAGATCTTAACCTATGAGGAAATGTCACTTTATCATCAGCCAGCAAATAGGAAGAGA
CCTATCATCTTGATTGGTCCACAGAACTGTGGCCAGAATGAATTGCGTCAGAGGCTCATGAACAAAGAAAAGGACCGCTTTGCATCTGCA
GTTCCTCATACAACCCGGAGTAGGCGAGACCAAGAAGTAGCCGGTAGAGATTACCACTTTGTTTCGCGGCAAGCATTCGAGGCAGACATA
GCAGCTGGAAAGTTCATTGAGCATGGTGAATTTGAGAAGAATTTGTATGGAACTAGCATAGATTCTGTACGGCAAGTGATCAACTCTGGC
AAAATATGTCTTTTAAGTCTTCGTACACAGTCATTGAAGACTCTCCGGAATTCAGATTTGAAACCATATATTATCTTCATTGCACCCCCT
TCACAAGAAAGACTTCGGGCATTATTGGCCAAAGAAGGCAAGAATCCAAAGCCTGAAGAGTTGAGAGAAATCATTGAGAAGACAAGAGAG
ATGGAGCAGAACAATGGCCACTACTTTGATACGGCAATTGTGAATTCCGATCTTGATAAAGCCTATCAGGAATTGCTTAGGTTAATTAAC
AAACTTGATACTGAACCTCAGTGGGTACCATCCACTTGGCTGAGGTGAAAGAAACATCCATTCTGTGGCATGTTGGACTTGATCTGGCAA
AAACTGCCAATAGGAGGACTGCCCGACACTGCAGCAAGATTGAGGATAAGATGGAAGGCAGCAGTATAAGCTGTAGATCTGTTCTTAGAT
CTCTTGAATTAGTGAGACGACAGTTCCCTTAGGCAGTTTGTGCATGGCATCCTTTATTCTCTATACATGGCTTTAGCGGTTCTTGCCTCA
TTTTGGGATTCTAAATGGAAGCTTTCAACAGAGCATTCCATTTTGTCCTGTTAAAACCTTTTGTTTTCACCTAAACCCTTTCTGCTTAGT
TGTATCTCTGTGAAAAACTTGTATACACAAGCGTCCATGTCTCACACAAATATTGATGTGATTATTCTTAAGTGTTAAATCATTAACACT
TAAATGACTTCATTGGGAATATTGAGCAGAGGGACTGTGCTTCTATGCACTGGGCAAGGCAGTATTTGCTTAGGAAACTAATTTAGTCAT
CAGAGATACTTTCCTAAAAAGGAAAAATAAAAAACAAAATGGTGCCACTTTGGGTTGAAGCTACTTTGTTAGGCTTGAATTCATTTATAT
GTCTTTTGATTCTTAAAAAAACAAAAAACATTCCATTAGAAGCACCAGTTTTTTTGCTCAGACTTTGTGGATCAGACTCTACACTCAACA
CACTCTAATCTACTTAAAGGTATACAAAATATGCTGATCTTTTTTAAATTATGATTTCCTGAATTTTTTTCTTAAGTCGTCTCAACTGAT
TTACTCACTTAGCTTCCCTTCCCTCATCAGCATAGTATAATAGAATGTATGTTACATTTTTATGAATGGCAGGTGTTCATTATAATCTGT
ATTGACTTAAAAAGTTTCTTCCTCATGATGCTAATAGTTTTTTGTATACATGGGAGGATAGCACATTTGACAGTTTTTGCATTTTTATGT
ATGAGCACAGTATCCTATGACTGTGCTACGTATATATAGGTAATAAACTGGAATTCTGTTGATGAATATAGCTGCTGTACTGTATATTAA
TATTTAATAGATCAACAAATGGTCATTGAAAACACTTGTTTAGCATTAGAATAAAATTATATATGTCCTTGGGAAATATTATGACAGTTG
ACTTTAAGATCAAAAGGAAGGGAAGACCTGAAAGTCATTTGAACATTTTAGGAAAAGAATATTGGAGAGAAAAAGGTATTAAATATATAG
AAATAGGTTTTTAACCTAACAAGGTCTGCCTCTTATGACGAGAATGCAACAGCTTGGTAAATCATAAAAGAAACATTTAAGCTAATAGGA
TTTTCGTACTGTCTCTATAGCTGTAGCTTTAAAATTCAACGTATATAATTGGCATGGAAACTTAATTTGCAGTCTTTTCAAGCCTTTAGG
ATAGTGTGATGTGTAACAAACAACCTCAAATGTGAATGCCTTGATTTTATTTTTATGGTGACTTTAGCTACAGCATTTCCTATACCCAGA
GCTAAACACTGGAATAATACTGACATCATTTAATTTAACATAAGCAATTATGTTTAAGGAGTAATTTGTGTCATGTACATATTTGATTGA
TTTTTTTTCTTCTACATAATTTTATTTGAACAAATGTAGACAGTTTATATGTCGCCTTTTTCTGTTCAAATTTGCATGGCCTATTAAGTT
GGCTGGAGAGTGTTTTATGTGGAAATATTTTCAAGATAATGTTCCTTAGGAAGAAAATAACATTCTTGGGTTGAGGGAAGGAATGCCATA
CACTACTGTCTCTTCAGATCTGAAATACTCCAGTTTAGAGCCAGGAAATTTCACAGGTCACACCGATTTTTAGCATTAAAAACTAAGGAA
TATACTTAGCACTTACTTAATCTTTTCAGTTTTCCAGTTTACGTCTCAGGAATGAAGTGTAGTCTATGGTTGACAATGGAGTTTTGTGAT
CCTGCTTATTGTAACTGACAACTGTTTTCAACTCCAAGAGCTAAACTATTGGCAGTTCATGTTAAGTTAGAGTGAGGGTGTAGGTAGTGT
CAGTGAGTGGCTCTTGTGCCTGCTGTAGACATTAGGCCTGCACTAGGGCCATGTGCTGTCAAGATTCAGGAACATGGCTTTAACAAGCAG
ATCTTGTATCAAGGCAGAGGTGATGCCATGCCATACTTTTAGGAAGTCTGAGATGATAAATATTTCAAGGTCAGTGAAGTCTATCAATCA
TTCTCCCCTTCCTCATCAGCAATGGTAGATAGAAATGTCCTAAACTTTTCTAAATCCTAGTGATGAGGATGTGCTGATATTCAACATAGT
CCTTAAAGTGAAAACTGAGTTGTTGCTGACCTCCACAAAAGAATATGGAAAAAAGCCTTGCTGTACACCTAGTTGTACAGCCACTCTGGC
CAATTCCATTTCCTGTCCCTCTGTGGTTCTGACTGGAGACCCCAGTGTGGGGGAGGTCTTACCATTTAATATAGAAATGATATCAATAAC
TAATGCTATGTACTTGGAAAATCCAAATAAGGAAGTTTTAGGTTGGTGCATAACTTTGTTTCTCAAATTTTCGTTGTCAGAACAAATGGA
AGGAGAATATTATTTAGACTAATCCAGATTTGCTTTCTATGAAAATCTAATGTCTGGATTATCTTCCTTTTCTCATGGCCTAAGAAATAA
GGATCAATAAGGAATGATTTGAATGTAATTTTGTGAATGTGTGGAAAATATAAAGCAGGGATTTAGCCTTAATAAAGGTAACCTTCTGAC
ATCTGTTGTTAATCCCCCTTTGTACTCTTTTCCTGTATCTGCACTGTTATTTTGAGATGTCATACTGTACACTGTATTGTAAAAATAAAA

>71751_71751_10_RAD51B-MPP5_RAD51B_chr14_68353921_ENST00000488612_MPP5_chr14_67770238_ENST00000555925_length(amino acids)=615AA_BP=261
LKVGCCRPGMGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSADFSPA
FLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLL
LTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPSDMHGTLTF
VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASA
VPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP

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Fusion Gene PPI Analysis for RAD51B-MPP5

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Hgene	RAD51B	chr14:68353921	chr14:67770238	ENST00000390683	+	6	10	1_75	252.0	367.0	RAD51C
Hgene	RAD51B	chr14:68353921	chr14:67770238	ENST00000471583	+	7	11	1_75	252.0	351.0	RAD51C
Hgene	RAD51B	chr14:68353921	chr14:67770238	ENST00000487270	+	7	11	1_75	252.0	385.0	RAD51C
Hgene	RAD51B	chr14:68353921	chr14:67770238	ENST00000488612	+	7	12	1_75	252.0	495.6666666666667	RAD51C

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Tgene	MPP5	chr14:68353921	chr14:67770238	ENST00000261681		6	15	181_243	321.0	676.0	LIN7C
Tgene	MPP5	chr14:68353921	chr14:67770238	ENST00000555925		6	15	181_243	287.0	642.0	LIN7C
Tgene	MPP5	chr14:68353921	chr14:67770238	ENST00000261681		6	15	21_140	321.0	676.0	PARD6B
Tgene	MPP5	chr14:68353921	chr14:67770238	ENST00000555925		6	15	21_140	287.0	642.0	PARD6B

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for RAD51B-MPP5

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for RAD51B-MPP5

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source