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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:RAP1GAP2-SGSM2 (FusionGDB2 ID:72166)

Fusion Gene Summary for RAP1GAP2-SGSM2

Fusion gene summary

Fusion gene information	Fusion gene name: RAP1GAP2-SGSM2
	Fusion gene ID: 72166
		Hgene	Tgene
	Gene symbol	RAP1GAP2	SGSM2
	Gene ID	23108	9905
	Gene name	RAP1 GTPase activating protein 2	small G protein signaling modulator 2
	Synonyms	GARNL4\|RAP1GA3	RUTBC1
	Cytomap	17p13.3	17p13.3
	Type of gene	protein-coding	protein-coding
	Description	rap1 GTPase-activating protein 2GTPase activating RANGAP domain-like 4GTPase activating Rap/RanGAP domain-like 4GTPase-activating Rap/Ran-GAP domain-like protein 4	small G protein signaling modulator 2RUN and TBC1 domain containing 1small G protein signaling modulator 2 protein
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000254695, ENST00000366401, ENST00000540393, ENST00000542807, ENST00000574709,	ENST00000268989, ENST00000426855, ENST00000574563,
Fusion gene scores	* DoF score	10 X 10 X 3=300	4 X 4 X 3=48
	# samples	10	4
	** MAII score	log2(10/300*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: RAP1GAP2 [Title/Abstract] AND SGSM2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	RAP1GAP2(2901670)-SGSM2(2281151), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across RAP1GAP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across SGSM2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-B6-A0RT-01A	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+

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Fusion Gene ORF analysis for RAP1GAP2-SGSM2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000254695	ENST00000268989	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
In-frame	ENST00000254695	ENST00000426855	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
In-frame	ENST00000254695	ENST00000574563	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
In-frame	ENST00000366401	ENST00000268989	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
In-frame	ENST00000366401	ENST00000426855	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
In-frame	ENST00000366401	ENST00000574563	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
In-frame	ENST00000540393	ENST00000268989	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
In-frame	ENST00000540393	ENST00000426855	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
In-frame	ENST00000540393	ENST00000574563	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
In-frame	ENST00000542807	ENST00000268989	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
In-frame	ENST00000542807	ENST00000426855	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
In-frame	ENST00000542807	ENST00000574563	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
intron-3CDS	ENST00000574709	ENST00000268989	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
intron-3CDS	ENST00000574709	ENST00000426855	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+
intron-3CDS	ENST00000574709	ENST00000574563	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000540393	RAP1GAP2	chr17	2901670	+	ENST00000268989	SGSM2	chr17	2281151	+	3263	1379	125	1732	535
ENST00000540393	RAP1GAP2	chr17	2901670	+	ENST00000426855	SGSM2	chr17	2281151	+	3271	1379	125	1732	535
ENST00000540393	RAP1GAP2	chr17	2901670	+	ENST00000574563	SGSM2	chr17	2281151	+	2055	1379	125	1675	516
ENST00000254695	RAP1GAP2	chr17	2901670	+	ENST00000268989	SGSM2	chr17	2281151	+	3174	1290	90	1643	517
ENST00000254695	RAP1GAP2	chr17	2901670	+	ENST00000426855	SGSM2	chr17	2281151	+	3182	1290	90	1643	517
ENST00000254695	RAP1GAP2	chr17	2901670	+	ENST00000574563	SGSM2	chr17	2281151	+	1966	1290	90	1586	498
ENST00000366401	RAP1GAP2	chr17	2901670	+	ENST00000268989	SGSM2	chr17	2281151	+	3129	1245	90	1598	502
ENST00000366401	RAP1GAP2	chr17	2901670	+	ENST00000426855	SGSM2	chr17	2281151	+	3137	1245	90	1598	502
ENST00000366401	RAP1GAP2	chr17	2901670	+	ENST00000574563	SGSM2	chr17	2281151	+	1921	1245	90	1541	483
ENST00000542807	RAP1GAP2	chr17	2901670	+	ENST00000268989	SGSM2	chr17	2281151	+	3130	1246	46	1599	517
ENST00000542807	RAP1GAP2	chr17	2901670	+	ENST00000426855	SGSM2	chr17	2281151	+	3138	1246	46	1599	517
ENST00000542807	RAP1GAP2	chr17	2901670	+	ENST00000574563	SGSM2	chr17	2281151	+	1922	1246	46	1542	498

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000540393	ENST00000268989	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.003759534	0.9962405
ENST00000540393	ENST00000426855	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.003735154	0.9962649
ENST00000540393	ENST00000574563	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.0026336	0.99736637
ENST00000254695	ENST00000268989	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.007008436	0.99299157
ENST00000254695	ENST00000426855	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.006959787	0.9930402
ENST00000254695	ENST00000574563	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.004069625	0.9959304
ENST00000366401	ENST00000268989	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.002927142	0.9970728
ENST00000366401	ENST00000426855	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.002891819	0.99710816
ENST00000366401	ENST00000574563	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.001914847	0.99808514
ENST00000542807	ENST00000268989	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.007088581	0.9929114
ENST00000542807	ENST00000426855	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.007041772	0.9929582
ENST00000542807	ENST00000574563	RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281151	+	0.004112011	0.99588805

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Fusion Genomic Features for RAP1GAP2-SGSM2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281150	+	7.47E-07	0.9999993
RAP1GAP2	chr17	2901670	+	SGSM2	chr17	2281150	+	7.47E-07	0.9999993

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RAP1GAP2-SGSM2

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:2901670/chr17:2281151)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

RAP1GAP2

chr17:2901670

chr17:2281151

ENST00000254695

586_726

400

2135.6666666666665

Compositional bias

Note=Ser-rich

Hgene

RAP1GAP2

chr17:2901670

chr17:2281151

ENST00000366401

586_726

385

2120.6666666666665

Compositional bias

Note=Ser-rich

Hgene

RAP1GAP2

chr17:2901670

chr17:2281151

ENST00000540393

586_726

381

909.6666666666666

Compositional bias

Note=Ser-rich

Hgene

RAP1GAP2

chr17:2901670

chr17:2281151

ENST00000542807

586_726

400

969.3333333333334

Compositional bias

Note=Ser-rich

Hgene

RAP1GAP2

chr17:2901670

chr17:2281151

ENST00000254695

248_464

400

2135.6666666666665

Domain

Rap-GAP

Hgene

RAP1GAP2

chr17:2901670

chr17:2281151

ENST00000366401

248_464

385

2120.6666666666665

Domain

Rap-GAP

Hgene

RAP1GAP2

chr17:2901670

chr17:2281151

ENST00000540393

248_464

381

909.6666666666666

Domain

Rap-GAP

Hgene

RAP1GAP2

chr17:2901670

chr17:2281151

ENST00000542807

248_464

400

969.3333333333334

Domain

Rap-GAP

Tgene

SGSM2

chr17:2901670

chr17:2281151

ENST00000268989

34_191

934

1052.0

Domain

RUN

Tgene

SGSM2

chr17:2901670

chr17:2281151

ENST00000268989

566_939

934

1052.0

Domain

Rab-GAP TBC

Tgene

SGSM2

chr17:2901670

chr17:2281151

ENST00000426855

34_191

889

1007.0

Domain

RUN

Tgene

SGSM2

chr17:2901670

chr17:2281151

ENST00000426855

566_939

889

1007.0

Domain

Rab-GAP TBC

Tgene

SGSM2

chr17:2901670

chr17:2281151

ENST00000574563

34_191

889

988.0

Domain

RUN

Tgene

SGSM2

chr17:2901670

chr17:2281151

ENST00000574563

566_939

889

988.0

Domain

Rab-GAP TBC

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Fusion Gene Sequence for RAP1GAP2-SGSM2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>72166_72166_1_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000254695_SGSM2_chr17_2281151_ENST00000268989_length(transcript)=3174nt_BP=1290nt
ACTGACCCCGCTGTACCACGGCCCTCTTGCGGACAGCCCCGGGGACGTCGTTGGGACATCGCTGGGACCCCGGGCTCTGCAGCCACAACC
ATGTTTGGCCGGAAGCGCAGTGTCTCCTTTGGGGGCTTCGGATGGATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAG
CTGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTCCCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTT
GAGATGCTGGAGAAAATGCAGGGGATCAAGCTTGAAGAGCAGAAGCCGGGACCCCAGAAGAACAAGGACGACTATATCCCATACCCCAGC
ATCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCATCCTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTG
GGCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGAAGAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGC
AAGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGATCATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATC
CTGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCGGGTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCC
TTGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAAGGCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTG
TACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGAAGTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGG
CAGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCCAGCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTG
CAGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGGACAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAG
ATCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGACGCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTG
GCCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACATGATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAG
ACCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGAGCTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTAC
TTCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCTGTATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGG
CACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCTGGTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTC
ACTGACATCATCAAGTTTTTCAATGAACGTGCTGAGCATCACGATGCCCAGGAGATCCTGCGGATTGCCCGGGACCTCGTCCACAAGGTG
CAGATGCTCATAGAGAACAAGTGAGCTGGGGCCAGGAGGCAGCAGCCGTGCAGAGCCTGGGCTCCGGCAGGGAGAGGTGCAGGGGAGTCA
CCGCCCAGACCTCCCCAGCCACCAACCGACCCCACCTCTGTTCCTAACAAAGCGGTTGTGAGCCTGGATCCGACTCCCGGCAGTGCTGAC
CCTGCAGGGCAAGTCAGGGGCCAGGATGCCCTCGGATCAGGGCCGGGATGGGAGGGGTCAGCCTCAGGGAGCAGCTGCCTTGGGGGACAC
ACCTACTCTGCTCCCCTCTCACACATCTGGGAGTAGCCCCACTGCCACCTGCAGCCGCAGCCTGGACTGCTGCCCACGAGTGAACCTGGG
GCCCCACAGGATTAACAGGGGCTATAGCGGCCTGGGCCCTACTCAGCTGGGGTGGCAGAGGGCGAGAGGCTCTGTGCTGTGTCCCTTCTG
AGGGTCCCTTTGCAGTCCCAGTATATTGTGCGTGCACCAGCCCCAGCTGGAGCAACCAAAACTGCTTCTGGTTTAGGCACACGTCACGGG
TGCGGGAGACCCGGGCACGGGAGACCCGGGCCGCCTTCAGGCCGCTCCCCCGAGATTCTGGGGCAGTCGGAAGATGTGGGCCCTGGGTGG
GAGCAGCCCACTTCAGCAGCACTGCCACTGCCTTTGGCCACCTGAGGTGACCCCCAGGCCTCCCCGGCCTTGTACAGTGTACCTCTGTGT
ATCTGTACAGCCTCGCTCCTGCCACCCCACCCTTGCGTTCTGCATTAGGTACTTCCCTGAAAACCACGTGTAAGAAGTGATGCTTTTGCC
AGTGGATGATCTGGAATGCGACCGGAGCACTTGCTCTGAGGAATCCCAGGGTGACTCTGTCGGGGAAGAATCCGGTCACAGCCTCCCCTC
AGAGACAGGCCTCAGTTCGAGGGCAGCCCATTATCTGTCGCAGACATCTGCCATGTCCCTGAGACTGCGGGAGGCAGGGGATGCATGGGT
GTCCCCATCTGTCCCTGGTGAGAAGCAAGGCTAGCTCTGCCTTCCACATGCTTCTCAGGATGCCAAGAGGCCTAGGAACCCAGAAACCCC
CTTGGAGGAGCTGTGTATGCGGGGGTGCCAGGAAGGGCATAGCTCCTGCCCCCAGGCCTAGGCATGCTGCTTGCTCGGCCATCCCCACTT
CCTCCTCTACCCCAACACATGCAGGCTAGGCCTTGCCCTGGAACATGGAGGCCCTGCCCGGGGCTGGGGCCTAGTCCAGCAGCCACCAAA
GTCTGGCAGACTTTCTGCATTTGAGAAACATGACAAAGGGCCCCGCAGCCCTTCTGCACCCAGCACAGCCTGCCCAGCCCAGCCCTGCCC
CCGGGCACTGCACAGCCTGTCTGGGGGCCAGACCACCCCATTGTCCATCCTTGTTGTCCGTGAGTCCTTGGCCTCCACCAAGCACGTGTG
GCCATTGTGTGCCTGCCTTAGTGACTCCGTGGTTTTGTGAGGAGCAGAGTGTGTATGATTTTTGCCTCAGAAACTATACTCTTCTGTGTA

>72166_72166_1_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000254695_SGSM2_chr17_2281151_ENST00000268989_length(amino acids)=517AA_BP=399
MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLEEQKPGPQKNKDDYIPYPS
IDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI
LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKAR
QTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV
AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAAR

--------------------------------------------------------------
>72166_72166_2_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000254695_SGSM2_chr17_2281151_ENST00000426855_length(transcript)=3182nt_BP=1290nt
ACTGACCCCGCTGTACCACGGCCCTCTTGCGGACAGCCCCGGGGACGTCGTTGGGACATCGCTGGGACCCCGGGCTCTGCAGCCACAACC
ATGTTTGGCCGGAAGCGCAGTGTCTCCTTTGGGGGCTTCGGATGGATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAG
CTGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTCCCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTT
GAGATGCTGGAGAAAATGCAGGGGATCAAGCTTGAAGAGCAGAAGCCGGGACCCCAGAAGAACAAGGACGACTATATCCCATACCCCAGC
ATCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCATCCTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTG
GGCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGAAGAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGC
AAGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGATCATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATC
CTGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCGGGTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCC
TTGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAAGGCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTG
TACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGAAGTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGG
CAGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCCAGCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTG
CAGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGGACAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAG
ATCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGACGCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTG
GCCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACATGATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAG
ACCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGAGCTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTAC
TTCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCTGTATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGG
CACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCTGGTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTC
ACTGACATCATCAAGTTTTTCAATGAACGTGCTGAGCATCACGATGCCCAGGAGATCCTGCGGATTGCCCGGGACCTCGTCCACAAGGTG
CAGATGCTCATAGAGAACAAGTGAGCTGGGGCCAGGAGGCAGCAGCCGTGCAGAGCCTGGGCTCCGGCAGGGAGAGGTGCAGGGGAGTCA
CCGCCCAGACCTCCCCAGCCACCAACCGACCCCACCTCTGTTCCTAACAAAGCGGTTGTGAGCCTGGATCCGACTCCCGGCAGTGCTGAC
CCTGCAGGGCAAGTCAGGGGCCAGGATGCCCTCGGATCAGGGCCGGGATGGGAGGGGTCAGCCTCAGGGAGCAGCTGCCTTGGGGGACAC
ACCTACTCTGCTCCCCTCTCACACATCTGGGAGTAGCCCCACTGCCACCTGCAGCCGCAGCCTGGACTGCTGCCCACGAGTGAACCTGGG
GCCCCACAGGATTAACAGGGGCTATAGCGGCCTGGGCCCTACTCAGCTGGGGTGGCAGAGGGCGAGAGGCTCTGTGCTGTGTCCCTTCTG
AGGGTCCCTTTGCAGTCCCAGTATATTGTGCGTGCACCAGCCCCAGCTGGAGCAACCAAAACTGCTTCTGGTTTAGGCACACGTCACGGG
TGCGGGAGACCCGGGCACGGGAGACCCGGGCCGCCTTCAGGCCGCTCCCCCGAGATTCTGGGGCAGTCGGAAGATGTGGGCCCTGGGTGG
GAGCAGCCCACTTCAGCAGCACTGCCACTGCCTTTGGCCACCTGAGGTGACCCCCAGGCCTCCCCGGCCTTGTACAGTGTACCTCTGTGT
ATCTGTACAGCCTCGCTCCTGCCACCCCACCCTTGCGTTCTGCATTAGGTACTTCCCTGAAAACCACGTGTAAGAAGTGATGCTTTTGCC
AGTGGATGATCTGGAATGCGACCGGAGCACTTGCTCTGAGGAATCCCAGGGTGACTCTGTCGGGGAAGAATCCGGTCACAGCCTCCCCTC
AGAGACAGGCCTCAGTTCGAGGGCAGCCCATTATCTGTCGCAGACATCTGCCATGTCCCTGAGACTGCGGGAGGCAGGGGATGCATGGGT
GTCCCCATCTGTCCCTGGTGAGAAGCAAGGCTAGCTCTGCCTTCCACATGCTTCTCAGGATGCCAAGAGGCCTAGGAACCCAGAAACCCC
CTTGGAGGAGCTGTGTATGCGGGGGTGCCAGGAAGGGCATAGCTCCTGCCCCCAGGCCTAGGCATGCTGCTTGCTCGGCCATCCCCACTT
CCTCCTCTACCCCAACACATGCAGGCTAGGCCTTGCCCTGGAACATGGAGGCCCTGCCCGGGGCTGGGGCCTAGTCCAGCAGCCACCAAA
GTCTGGCAGACTTTCTGCATTTGAGAAACATGACAAAGGGCCCCGCAGCCCTTCTGCACCCAGCACAGCCTGCCCAGCCCAGCCCTGCCC
CCGGGCACTGCACAGCCTGTCTGGGGGCCAGACCACCCCATTGTCCATCCTTGTTGTCCGTGAGTCCTTGGCCTCCACCAAGCACGTGTG
GCCATTGTGTGCCTGCCTTAGTGACTCCGTGGTTTTGTGAGGAGCAGAGTGTGTATGATTTTTGCCTCAGAAACTATACTCTTCTGTGTA

>72166_72166_2_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000254695_SGSM2_chr17_2281151_ENST00000426855_length(amino acids)=517AA_BP=399
MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLEEQKPGPQKNKDDYIPYPS
IDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI
LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKAR
QTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV
AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAAR

--------------------------------------------------------------
>72166_72166_3_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000254695_SGSM2_chr17_2281151_ENST00000574563_length(transcript)=1966nt_BP=1290nt
ACTGACCCCGCTGTACCACGGCCCTCTTGCGGACAGCCCCGGGGACGTCGTTGGGACATCGCTGGGACCCCGGGCTCTGCAGCCACAACC
ATGTTTGGCCGGAAGCGCAGTGTCTCCTTTGGGGGCTTCGGATGGATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAG
CTGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTCCCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTT
GAGATGCTGGAGAAAATGCAGGGGATCAAGCTTGAAGAGCAGAAGCCGGGACCCCAGAAGAACAAGGACGACTATATCCCATACCCCAGC
ATCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCATCCTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTG
GGCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGAAGAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGC
AAGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGATCATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATC
CTGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCGGGTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCC
TTGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAAGGCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTG
TACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGAAGTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGG
CAGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCCAGCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTG
CAGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGGACAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAG
ATCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGACGCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTG
GCCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACATGATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAG
ACCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGAGCTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTAC
TTCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCTGTATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGG
CACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCTGGTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTC
ACTGACATCATCAAGTTTTTCAATGGTACTTCCCTGAAAACCACGTGTAAGAAGTGATGCTTTTGCCAGTGGATGATCTGGAATGCGACC
GGAGCACTTGCTCTGAGGAATCCCAGGGTGACTCTGTCGGGGAAGAATCCGGTCACAGCCTCCCCTCAGAGACAGGCCTCAGTTCGAGGG
CAGCCCATTATCTGTCGCAGACATCTGCCATGTCCCTGAGACTGCGGGAGGCAGGGGATGCATGGGTGTCCCCATCTGTCCCTGGTGAGA
AGCAAGGCTAGCTCTGCCTTCCACATGCTTCTCAGGATGCCAAGAGGCCTAGGAACCCAGAAACCCCCTTGGAGGAGCTGTGTATGCGGG

>72166_72166_3_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000254695_SGSM2_chr17_2281151_ENST00000574563_length(amino acids)=498AA_BP=399
MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLEEQKPGPQKNKDDYIPYPS
IDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI
LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKAR
QTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV
AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAAR

--------------------------------------------------------------
>72166_72166_4_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000366401_SGSM2_chr17_2281151_ENST00000268989_length(transcript)=3129nt_BP=1245nt
ACTGACCCCGCTGTACCACGGCCCTCTTGCGGACAGCCCCGGGGACGTCGTTGGGACATCGCTGGGACCCCGGGCTCTGCAGCCACAACC
ATGTTTGGCCGGAAGCGCAGTGTCTCCTTTGGGGGCTTCGGATGGATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAG
CTGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTCCCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTT
GAGATGCTGGAGAAAATGCAGGACGACTATATCCCATACCCCAGCATCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCATC
CTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTGGGCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGAA
GAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGCAAGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGAT
CATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATCCTGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCGG
GTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCCTTGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAAG
GCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTGTACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGAA
GTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGGCAGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCCA
GCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTGCAGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGGA
CAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAGATCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGAC
GCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTGGCCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACATG
ATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAGACCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGAG
CTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTACTTCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCTG
TATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGGCACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCTG
GTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTCACTGACATCATCAAGTTTTTCAATGAACGTGCTGAGCATCACGAT
GCCCAGGAGATCCTGCGGATTGCCCGGGACCTCGTCCACAAGGTGCAGATGCTCATAGAGAACAAGTGAGCTGGGGCCAGGAGGCAGCAG
CCGTGCAGAGCCTGGGCTCCGGCAGGGAGAGGTGCAGGGGAGTCACCGCCCAGACCTCCCCAGCCACCAACCGACCCCACCTCTGTTCCT
AACAAAGCGGTTGTGAGCCTGGATCCGACTCCCGGCAGTGCTGACCCTGCAGGGCAAGTCAGGGGCCAGGATGCCCTCGGATCAGGGCCG
GGATGGGAGGGGTCAGCCTCAGGGAGCAGCTGCCTTGGGGGACACACCTACTCTGCTCCCCTCTCACACATCTGGGAGTAGCCCCACTGC
CACCTGCAGCCGCAGCCTGGACTGCTGCCCACGAGTGAACCTGGGGCCCCACAGGATTAACAGGGGCTATAGCGGCCTGGGCCCTACTCA
GCTGGGGTGGCAGAGGGCGAGAGGCTCTGTGCTGTGTCCCTTCTGAGGGTCCCTTTGCAGTCCCAGTATATTGTGCGTGCACCAGCCCCA
GCTGGAGCAACCAAAACTGCTTCTGGTTTAGGCACACGTCACGGGTGCGGGAGACCCGGGCACGGGAGACCCGGGCCGCCTTCAGGCCGC
TCCCCCGAGATTCTGGGGCAGTCGGAAGATGTGGGCCCTGGGTGGGAGCAGCCCACTTCAGCAGCACTGCCACTGCCTTTGGCCACCTGA
GGTGACCCCCAGGCCTCCCCGGCCTTGTACAGTGTACCTCTGTGTATCTGTACAGCCTCGCTCCTGCCACCCCACCCTTGCGTTCTGCAT
TAGGTACTTCCCTGAAAACCACGTGTAAGAAGTGATGCTTTTGCCAGTGGATGATCTGGAATGCGACCGGAGCACTTGCTCTGAGGAATC
CCAGGGTGACTCTGTCGGGGAAGAATCCGGTCACAGCCTCCCCTCAGAGACAGGCCTCAGTTCGAGGGCAGCCCATTATCTGTCGCAGAC
ATCTGCCATGTCCCTGAGACTGCGGGAGGCAGGGGATGCATGGGTGTCCCCATCTGTCCCTGGTGAGAAGCAAGGCTAGCTCTGCCTTCC
ACATGCTTCTCAGGATGCCAAGAGGCCTAGGAACCCAGAAACCCCCTTGGAGGAGCTGTGTATGCGGGGGTGCCAGGAAGGGCATAGCTC
CTGCCCCCAGGCCTAGGCATGCTGCTTGCTCGGCCATCCCCACTTCCTCCTCTACCCCAACACATGCAGGCTAGGCCTTGCCCTGGAACA
TGGAGGCCCTGCCCGGGGCTGGGGCCTAGTCCAGCAGCCACCAAAGTCTGGCAGACTTTCTGCATTTGAGAAACATGACAAAGGGCCCCG
CAGCCCTTCTGCACCCAGCACAGCCTGCCCAGCCCAGCCCTGCCCCCGGGCACTGCACAGCCTGTCTGGGGGCCAGACCACCCCATTGTC
CATCCTTGTTGTCCGTGAGTCCTTGGCCTCCACCAAGCACGTGTGGCCATTGTGTGCCTGCCTTAGTGACTCCGTGGTTTTGTGAGGAGC

>72166_72166_4_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000366401_SGSM2_chr17_2281151_ENST00000268989_length(amino acids)=502AA_BP=384
MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQDDYIPYPSIDEVVEKGGPYPQVI
LPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLILSVKCEEAEGIEYLR
VILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESP
AFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDM
IASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALAL

--------------------------------------------------------------
>72166_72166_5_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000366401_SGSM2_chr17_2281151_ENST00000426855_length(transcript)=3137nt_BP=1245nt
ACTGACCCCGCTGTACCACGGCCCTCTTGCGGACAGCCCCGGGGACGTCGTTGGGACATCGCTGGGACCCCGGGCTCTGCAGCCACAACC
ATGTTTGGCCGGAAGCGCAGTGTCTCCTTTGGGGGCTTCGGATGGATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAG
CTGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTCCCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTT
GAGATGCTGGAGAAAATGCAGGACGACTATATCCCATACCCCAGCATCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCATC
CTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTGGGCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGAA
GAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGCAAGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGAT
CATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATCCTGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCGG
GTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCCTTGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAAG
GCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTGTACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGAA
GTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGGCAGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCCA
GCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTGCAGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGGA
CAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAGATCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGAC
GCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTGGCCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACATG
ATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAGACCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGAG
CTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTACTTCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCTG
TATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGGCACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCTG
GTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTCACTGACATCATCAAGTTTTTCAATGAACGTGCTGAGCATCACGAT
GCCCAGGAGATCCTGCGGATTGCCCGGGACCTCGTCCACAAGGTGCAGATGCTCATAGAGAACAAGTGAGCTGGGGCCAGGAGGCAGCAG
CCGTGCAGAGCCTGGGCTCCGGCAGGGAGAGGTGCAGGGGAGTCACCGCCCAGACCTCCCCAGCCACCAACCGACCCCACCTCTGTTCCT
AACAAAGCGGTTGTGAGCCTGGATCCGACTCCCGGCAGTGCTGACCCTGCAGGGCAAGTCAGGGGCCAGGATGCCCTCGGATCAGGGCCG
GGATGGGAGGGGTCAGCCTCAGGGAGCAGCTGCCTTGGGGGACACACCTACTCTGCTCCCCTCTCACACATCTGGGAGTAGCCCCACTGC
CACCTGCAGCCGCAGCCTGGACTGCTGCCCACGAGTGAACCTGGGGCCCCACAGGATTAACAGGGGCTATAGCGGCCTGGGCCCTACTCA
GCTGGGGTGGCAGAGGGCGAGAGGCTCTGTGCTGTGTCCCTTCTGAGGGTCCCTTTGCAGTCCCAGTATATTGTGCGTGCACCAGCCCCA
GCTGGAGCAACCAAAACTGCTTCTGGTTTAGGCACACGTCACGGGTGCGGGAGACCCGGGCACGGGAGACCCGGGCCGCCTTCAGGCCGC
TCCCCCGAGATTCTGGGGCAGTCGGAAGATGTGGGCCCTGGGTGGGAGCAGCCCACTTCAGCAGCACTGCCACTGCCTTTGGCCACCTGA
GGTGACCCCCAGGCCTCCCCGGCCTTGTACAGTGTACCTCTGTGTATCTGTACAGCCTCGCTCCTGCCACCCCACCCTTGCGTTCTGCAT
TAGGTACTTCCCTGAAAACCACGTGTAAGAAGTGATGCTTTTGCCAGTGGATGATCTGGAATGCGACCGGAGCACTTGCTCTGAGGAATC
CCAGGGTGACTCTGTCGGGGAAGAATCCGGTCACAGCCTCCCCTCAGAGACAGGCCTCAGTTCGAGGGCAGCCCATTATCTGTCGCAGAC
ATCTGCCATGTCCCTGAGACTGCGGGAGGCAGGGGATGCATGGGTGTCCCCATCTGTCCCTGGTGAGAAGCAAGGCTAGCTCTGCCTTCC
ACATGCTTCTCAGGATGCCAAGAGGCCTAGGAACCCAGAAACCCCCTTGGAGGAGCTGTGTATGCGGGGGTGCCAGGAAGGGCATAGCTC
CTGCCCCCAGGCCTAGGCATGCTGCTTGCTCGGCCATCCCCACTTCCTCCTCTACCCCAACACATGCAGGCTAGGCCTTGCCCTGGAACA
TGGAGGCCCTGCCCGGGGCTGGGGCCTAGTCCAGCAGCCACCAAAGTCTGGCAGACTTTCTGCATTTGAGAAACATGACAAAGGGCCCCG
CAGCCCTTCTGCACCCAGCACAGCCTGCCCAGCCCAGCCCTGCCCCCGGGCACTGCACAGCCTGTCTGGGGGCCAGACCACCCCATTGTC
CATCCTTGTTGTCCGTGAGTCCTTGGCCTCCACCAAGCACGTGTGGCCATTGTGTGCCTGCCTTAGTGACTCCGTGGTTTTGTGAGGAGC

>72166_72166_5_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000366401_SGSM2_chr17_2281151_ENST00000426855_length(amino acids)=502AA_BP=384
MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQDDYIPYPSIDEVVEKGGPYPQVI
LPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLILSVKCEEAEGIEYLR
VILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESP
AFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDM
IASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALAL

--------------------------------------------------------------
>72166_72166_6_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000366401_SGSM2_chr17_2281151_ENST00000574563_length(transcript)=1921nt_BP=1245nt
ACTGACCCCGCTGTACCACGGCCCTCTTGCGGACAGCCCCGGGGACGTCGTTGGGACATCGCTGGGACCCCGGGCTCTGCAGCCACAACC
ATGTTTGGCCGGAAGCGCAGTGTCTCCTTTGGGGGCTTCGGATGGATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAG
CTGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTCCCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTT
GAGATGCTGGAGAAAATGCAGGACGACTATATCCCATACCCCAGCATCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCATC
CTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTGGGCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGAA
GAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGCAAGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGAT
CATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATCCTGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCGG
GTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCCTTGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAAG
GCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTGTACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGAA
GTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGGCAGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCCA
GCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTGCAGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGGA
CAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAGATCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGAC
GCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTGGCCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACATG
ATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAGACCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGAG
CTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTACTTCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCTG
TATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGGCACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCTG
GTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTCACTGACATCATCAAGTTTTTCAATGGTACTTCCCTGAAAACCACG
TGTAAGAAGTGATGCTTTTGCCAGTGGATGATCTGGAATGCGACCGGAGCACTTGCTCTGAGGAATCCCAGGGTGACTCTGTCGGGGAAG
AATCCGGTCACAGCCTCCCCTCAGAGACAGGCCTCAGTTCGAGGGCAGCCCATTATCTGTCGCAGACATCTGCCATGTCCCTGAGACTGC
GGGAGGCAGGGGATGCATGGGTGTCCCCATCTGTCCCTGGTGAGAAGCAAGGCTAGCTCTGCCTTCCACATGCTTCTCAGGATGCCAAGA
GGCCTAGGAACCCAGAAACCCCCTTGGAGGAGCTGTGTATGCGGGGGTGCCAGGAAGGGCATAGCTCCTGCCCCCAGGCCTAGGCATGCT

>72166_72166_6_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000366401_SGSM2_chr17_2281151_ENST00000574563_length(amino acids)=483AA_BP=384
MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQDDYIPYPSIDEVVEKGGPYPQVI
LPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLILSVKCEEAEGIEYLR
VILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESP
AFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDM
IASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALAL

--------------------------------------------------------------
>72166_72166_7_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000540393_SGSM2_chr17_2281151_ENST00000268989_length(transcript)=3263nt_BP=1379nt
GCAGACAGACATCGGCACGTATGGACGGCGCGAGCCGGTACTGCGTTCCGGAGGAGCCATCCGGCGTCACAGGCTGTGCTGGGGAGGTGG
GGTGACCGTCCTCAGAAACCCCCGCGGGCGGGGCGCTGCACACACGTCCACCTATAGGGTGTGTGTGCGTGCGTGAGGTGTGCAGCCCCT
GTCAGGATCTGGCGAGAGAAGCTGACCGGGATGGAGGTCAGAGGATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAGC
TGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTCCCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTTG
AGATGCTGGAGAAAATGCAGGGGATCAAGCTTGAAGAGCAGAAGCCGGGACCCCAGAAGAACAAGGACGACTATATCCCATACCCCAGCA
TCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCATCCTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTGG
GCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGAAGAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGCA
AGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGATCATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATCC
TGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCGGGTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCCT
TGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAAGGCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTGT
ACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGAAGTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGGC
AGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCCAGCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTGC
AGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGGACAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAGA
TCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGACGCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTGG
CCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACATGATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAGA
CCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGAGCTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTACT
TCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCTGTATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGGC
ACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCTGGTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTCA
CTGACATCATCAAGTTTTTCAATGAACGTGCTGAGCATCACGATGCCCAGGAGATCCTGCGGATTGCCCGGGACCTCGTCCACAAGGTGC
AGATGCTCATAGAGAACAAGTGAGCTGGGGCCAGGAGGCAGCAGCCGTGCAGAGCCTGGGCTCCGGCAGGGAGAGGTGCAGGGGAGTCAC
CGCCCAGACCTCCCCAGCCACCAACCGACCCCACCTCTGTTCCTAACAAAGCGGTTGTGAGCCTGGATCCGACTCCCGGCAGTGCTGACC
CTGCAGGGCAAGTCAGGGGCCAGGATGCCCTCGGATCAGGGCCGGGATGGGAGGGGTCAGCCTCAGGGAGCAGCTGCCTTGGGGGACACA
CCTACTCTGCTCCCCTCTCACACATCTGGGAGTAGCCCCACTGCCACCTGCAGCCGCAGCCTGGACTGCTGCCCACGAGTGAACCTGGGG
CCCCACAGGATTAACAGGGGCTATAGCGGCCTGGGCCCTACTCAGCTGGGGTGGCAGAGGGCGAGAGGCTCTGTGCTGTGTCCCTTCTGA
GGGTCCCTTTGCAGTCCCAGTATATTGTGCGTGCACCAGCCCCAGCTGGAGCAACCAAAACTGCTTCTGGTTTAGGCACACGTCACGGGT
GCGGGAGACCCGGGCACGGGAGACCCGGGCCGCCTTCAGGCCGCTCCCCCGAGATTCTGGGGCAGTCGGAAGATGTGGGCCCTGGGTGGG
AGCAGCCCACTTCAGCAGCACTGCCACTGCCTTTGGCCACCTGAGGTGACCCCCAGGCCTCCCCGGCCTTGTACAGTGTACCTCTGTGTA
TCTGTACAGCCTCGCTCCTGCCACCCCACCCTTGCGTTCTGCATTAGGTACTTCCCTGAAAACCACGTGTAAGAAGTGATGCTTTTGCCA
GTGGATGATCTGGAATGCGACCGGAGCACTTGCTCTGAGGAATCCCAGGGTGACTCTGTCGGGGAAGAATCCGGTCACAGCCTCCCCTCA
GAGACAGGCCTCAGTTCGAGGGCAGCCCATTATCTGTCGCAGACATCTGCCATGTCCCTGAGACTGCGGGAGGCAGGGGATGCATGGGTG
TCCCCATCTGTCCCTGGTGAGAAGCAAGGCTAGCTCTGCCTTCCACATGCTTCTCAGGATGCCAAGAGGCCTAGGAACCCAGAAACCCCC
TTGGAGGAGCTGTGTATGCGGGGGTGCCAGGAAGGGCATAGCTCCTGCCCCCAGGCCTAGGCATGCTGCTTGCTCGGCCATCCCCACTTC
CTCCTCTACCCCAACACATGCAGGCTAGGCCTTGCCCTGGAACATGGAGGCCCTGCCCGGGGCTGGGGCCTAGTCCAGCAGCCACCAAAG
TCTGGCAGACTTTCTGCATTTGAGAAACATGACAAAGGGCCCCGCAGCCCTTCTGCACCCAGCACAGCCTGCCCAGCCCAGCCCTGCCCC
CGGGCACTGCACAGCCTGTCTGGGGGCCAGACCACCCCATTGTCCATCCTTGTTGTCCGTGAGTCCTTGGCCTCCACCAAGCACGTGTGG
CCATTGTGTGCCTGCCTTAGTGACTCCGTGGTTTTGTGAGGAGCAGAGTGTGTATGATTTTTGCCTCAGAAACTATACTCTTCTGTGTAA

>72166_72166_7_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000540393_SGSM2_chr17_2281151_ENST00000268989_length(amino acids)=535AA_BP=417
MHTRPPIGCVCVREVCSPCQDLAREADRDGGQRIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLE
EQKPGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFL
GKDHLNFYCTGSSLGNLILSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYD
EHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFT
DGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKR

--------------------------------------------------------------
>72166_72166_8_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000540393_SGSM2_chr17_2281151_ENST00000426855_length(transcript)=3271nt_BP=1379nt
GCAGACAGACATCGGCACGTATGGACGGCGCGAGCCGGTACTGCGTTCCGGAGGAGCCATCCGGCGTCACAGGCTGTGCTGGGGAGGTGG
GGTGACCGTCCTCAGAAACCCCCGCGGGCGGGGCGCTGCACACACGTCCACCTATAGGGTGTGTGTGCGTGCGTGAGGTGTGCAGCCCCT
GTCAGGATCTGGCGAGAGAAGCTGACCGGGATGGAGGTCAGAGGATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAGC
TGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTCCCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTTG
AGATGCTGGAGAAAATGCAGGGGATCAAGCTTGAAGAGCAGAAGCCGGGACCCCAGAAGAACAAGGACGACTATATCCCATACCCCAGCA
TCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCATCCTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTGG
GCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGAAGAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGCA
AGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGATCATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATCC
TGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCGGGTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCCT
TGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAAGGCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTGT
ACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGAAGTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGGC
AGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCCAGCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTGC
AGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGGACAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAGA
TCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGACGCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTGG
CCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACATGATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAGA
CCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGAGCTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTACT
TCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCTGTATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGGC
ACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCTGGTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTCA
CTGACATCATCAAGTTTTTCAATGAACGTGCTGAGCATCACGATGCCCAGGAGATCCTGCGGATTGCCCGGGACCTCGTCCACAAGGTGC
AGATGCTCATAGAGAACAAGTGAGCTGGGGCCAGGAGGCAGCAGCCGTGCAGAGCCTGGGCTCCGGCAGGGAGAGGTGCAGGGGAGTCAC
CGCCCAGACCTCCCCAGCCACCAACCGACCCCACCTCTGTTCCTAACAAAGCGGTTGTGAGCCTGGATCCGACTCCCGGCAGTGCTGACC
CTGCAGGGCAAGTCAGGGGCCAGGATGCCCTCGGATCAGGGCCGGGATGGGAGGGGTCAGCCTCAGGGAGCAGCTGCCTTGGGGGACACA
CCTACTCTGCTCCCCTCTCACACATCTGGGAGTAGCCCCACTGCCACCTGCAGCCGCAGCCTGGACTGCTGCCCACGAGTGAACCTGGGG
CCCCACAGGATTAACAGGGGCTATAGCGGCCTGGGCCCTACTCAGCTGGGGTGGCAGAGGGCGAGAGGCTCTGTGCTGTGTCCCTTCTGA
GGGTCCCTTTGCAGTCCCAGTATATTGTGCGTGCACCAGCCCCAGCTGGAGCAACCAAAACTGCTTCTGGTTTAGGCACACGTCACGGGT
GCGGGAGACCCGGGCACGGGAGACCCGGGCCGCCTTCAGGCCGCTCCCCCGAGATTCTGGGGCAGTCGGAAGATGTGGGCCCTGGGTGGG
AGCAGCCCACTTCAGCAGCACTGCCACTGCCTTTGGCCACCTGAGGTGACCCCCAGGCCTCCCCGGCCTTGTACAGTGTACCTCTGTGTA
TCTGTACAGCCTCGCTCCTGCCACCCCACCCTTGCGTTCTGCATTAGGTACTTCCCTGAAAACCACGTGTAAGAAGTGATGCTTTTGCCA
GTGGATGATCTGGAATGCGACCGGAGCACTTGCTCTGAGGAATCCCAGGGTGACTCTGTCGGGGAAGAATCCGGTCACAGCCTCCCCTCA
GAGACAGGCCTCAGTTCGAGGGCAGCCCATTATCTGTCGCAGACATCTGCCATGTCCCTGAGACTGCGGGAGGCAGGGGATGCATGGGTG
TCCCCATCTGTCCCTGGTGAGAAGCAAGGCTAGCTCTGCCTTCCACATGCTTCTCAGGATGCCAAGAGGCCTAGGAACCCAGAAACCCCC
TTGGAGGAGCTGTGTATGCGGGGGTGCCAGGAAGGGCATAGCTCCTGCCCCCAGGCCTAGGCATGCTGCTTGCTCGGCCATCCCCACTTC
CTCCTCTACCCCAACACATGCAGGCTAGGCCTTGCCCTGGAACATGGAGGCCCTGCCCGGGGCTGGGGCCTAGTCCAGCAGCCACCAAAG
TCTGGCAGACTTTCTGCATTTGAGAAACATGACAAAGGGCCCCGCAGCCCTTCTGCACCCAGCACAGCCTGCCCAGCCCAGCCCTGCCCC
CGGGCACTGCACAGCCTGTCTGGGGGCCAGACCACCCCATTGTCCATCCTTGTTGTCCGTGAGTCCTTGGCCTCCACCAAGCACGTGTGG
CCATTGTGTGCCTGCCTTAGTGACTCCGTGGTTTTGTGAGGAGCAGAGTGTGTATGATTTTTGCCTCAGAAACTATACTCTTCTGTGTAA

>72166_72166_8_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000540393_SGSM2_chr17_2281151_ENST00000426855_length(amino acids)=535AA_BP=417
MHTRPPIGCVCVREVCSPCQDLAREADRDGGQRIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLE
EQKPGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFL
GKDHLNFYCTGSSLGNLILSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYD
EHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFT
DGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKR

--------------------------------------------------------------
>72166_72166_9_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000540393_SGSM2_chr17_2281151_ENST00000574563_length(transcript)=2055nt_BP=1379nt
GCAGACAGACATCGGCACGTATGGACGGCGCGAGCCGGTACTGCGTTCCGGAGGAGCCATCCGGCGTCACAGGCTGTGCTGGGGAGGTGG
GGTGACCGTCCTCAGAAACCCCCGCGGGCGGGGCGCTGCACACACGTCCACCTATAGGGTGTGTGTGCGTGCGTGAGGTGTGCAGCCCCT
GTCAGGATCTGGCGAGAGAAGCTGACCGGGATGGAGGTCAGAGGATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAGC
TGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTCCCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTTG
AGATGCTGGAGAAAATGCAGGGGATCAAGCTTGAAGAGCAGAAGCCGGGACCCCAGAAGAACAAGGACGACTATATCCCATACCCCAGCA
TCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCATCCTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTGG
GCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGAAGAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGCA
AGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGATCATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATCC
TGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCGGGTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCCT
TGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAAGGCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTGT
ACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGAAGTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGGC
AGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCCAGCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTGC
AGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGGACAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAGA
TCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGACGCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTGG
CCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACATGATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAGA
CCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGAGCTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTACT
TCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCTGTATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGGC
ACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCTGGTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTCA
CTGACATCATCAAGTTTTTCAATGGTACTTCCCTGAAAACCACGTGTAAGAAGTGATGCTTTTGCCAGTGGATGATCTGGAATGCGACCG
GAGCACTTGCTCTGAGGAATCCCAGGGTGACTCTGTCGGGGAAGAATCCGGTCACAGCCTCCCCTCAGAGACAGGCCTCAGTTCGAGGGC
AGCCCATTATCTGTCGCAGACATCTGCCATGTCCCTGAGACTGCGGGAGGCAGGGGATGCATGGGTGTCCCCATCTGTCCCTGGTGAGAA
GCAAGGCTAGCTCTGCCTTCCACATGCTTCTCAGGATGCCAAGAGGCCTAGGAACCCAGAAACCCCCTTGGAGGAGCTGTGTATGCGGGG

>72166_72166_9_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000540393_SGSM2_chr17_2281151_ENST00000574563_length(amino acids)=516AA_BP=417
MHTRPPIGCVCVREVCSPCQDLAREADRDGGQRIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLE
EQKPGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFL
GKDHLNFYCTGSSLGNLILSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYD
EHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFT
DGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKR

--------------------------------------------------------------
>72166_72166_10_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000542807_SGSM2_chr17_2281151_ENST00000268989_length(transcript)=3130nt_BP=1246nt
ACGTCGTTGGGACATCGCTGGGACCCCGGGCTCTGCAGCCACAACCATGTTTGGCCGGAAGCGCAGTGTCTCCTTTGGGGGCTTCGGATG
GATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAGCTGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTC
CCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTTGAGATGCTGGAGAAAATGCAGGGGATCAAGCTTGAAGAGCAGAA
GCCGGGACCCCAGAAGAACAAGGACGACTATATCCCATACCCCAGCATCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCAT
CCTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTGGGCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGA
AGAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGCAAGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGA
TCATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATCCTGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCG
GGTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCCTTGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAA
GGCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTGTACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGA
AGTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGGCAGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCC
AGCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTGCAGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGG
ACAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAGATCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGA
CGCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTGGCCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACAT
GATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAGACCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGA
GCTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTACTTCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCT
GTATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGGCACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCT
GGTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTCACTGACATCATCAAGTTTTTCAATGAACGTGCTGAGCATCACGA
TGCCCAGGAGATCCTGCGGATTGCCCGGGACCTCGTCCACAAGGTGCAGATGCTCATAGAGAACAAGTGAGCTGGGGCCAGGAGGCAGCA
GCCGTGCAGAGCCTGGGCTCCGGCAGGGAGAGGTGCAGGGGAGTCACCGCCCAGACCTCCCCAGCCACCAACCGACCCCACCTCTGTTCC
TAACAAAGCGGTTGTGAGCCTGGATCCGACTCCCGGCAGTGCTGACCCTGCAGGGCAAGTCAGGGGCCAGGATGCCCTCGGATCAGGGCC
GGGATGGGAGGGGTCAGCCTCAGGGAGCAGCTGCCTTGGGGGACACACCTACTCTGCTCCCCTCTCACACATCTGGGAGTAGCCCCACTG
CCACCTGCAGCCGCAGCCTGGACTGCTGCCCACGAGTGAACCTGGGGCCCCACAGGATTAACAGGGGCTATAGCGGCCTGGGCCCTACTC
AGCTGGGGTGGCAGAGGGCGAGAGGCTCTGTGCTGTGTCCCTTCTGAGGGTCCCTTTGCAGTCCCAGTATATTGTGCGTGCACCAGCCCC
AGCTGGAGCAACCAAAACTGCTTCTGGTTTAGGCACACGTCACGGGTGCGGGAGACCCGGGCACGGGAGACCCGGGCCGCCTTCAGGCCG
CTCCCCCGAGATTCTGGGGCAGTCGGAAGATGTGGGCCCTGGGTGGGAGCAGCCCACTTCAGCAGCACTGCCACTGCCTTTGGCCACCTG
AGGTGACCCCCAGGCCTCCCCGGCCTTGTACAGTGTACCTCTGTGTATCTGTACAGCCTCGCTCCTGCCACCCCACCCTTGCGTTCTGCA
TTAGGTACTTCCCTGAAAACCACGTGTAAGAAGTGATGCTTTTGCCAGTGGATGATCTGGAATGCGACCGGAGCACTTGCTCTGAGGAAT
CCCAGGGTGACTCTGTCGGGGAAGAATCCGGTCACAGCCTCCCCTCAGAGACAGGCCTCAGTTCGAGGGCAGCCCATTATCTGTCGCAGA
CATCTGCCATGTCCCTGAGACTGCGGGAGGCAGGGGATGCATGGGTGTCCCCATCTGTCCCTGGTGAGAAGCAAGGCTAGCTCTGCCTTC
CACATGCTTCTCAGGATGCCAAGAGGCCTAGGAACCCAGAAACCCCCTTGGAGGAGCTGTGTATGCGGGGGTGCCAGGAAGGGCATAGCT
CCTGCCCCCAGGCCTAGGCATGCTGCTTGCTCGGCCATCCCCACTTCCTCCTCTACCCCAACACATGCAGGCTAGGCCTTGCCCTGGAAC
ATGGAGGCCCTGCCCGGGGCTGGGGCCTAGTCCAGCAGCCACCAAAGTCTGGCAGACTTTCTGCATTTGAGAAACATGACAAAGGGCCCC
GCAGCCCTTCTGCACCCAGCACAGCCTGCCCAGCCCAGCCCTGCCCCCGGGCACTGCACAGCCTGTCTGGGGGCCAGACCACCCCATTGT
CCATCCTTGTTGTCCGTGAGTCCTTGGCCTCCACCAAGCACGTGTGGCCATTGTGTGCCTGCCTTAGTGACTCCGTGGTTTTGTGAGGAG

>72166_72166_10_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000542807_SGSM2_chr17_2281151_ENST00000268989_length(amino acids)=517AA_BP=399
MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLEEQKPGPQKNKDDYIPYPS
IDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI
LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKAR
QTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV
AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAAR

--------------------------------------------------------------
>72166_72166_11_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000542807_SGSM2_chr17_2281151_ENST00000426855_length(transcript)=3138nt_BP=1246nt
ACGTCGTTGGGACATCGCTGGGACCCCGGGCTCTGCAGCCACAACCATGTTTGGCCGGAAGCGCAGTGTCTCCTTTGGGGGCTTCGGATG
GATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAGCTGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTC
CCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTTGAGATGCTGGAGAAAATGCAGGGGATCAAGCTTGAAGAGCAGAA
GCCGGGACCCCAGAAGAACAAGGACGACTATATCCCATACCCCAGCATCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCAT
CCTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTGGGCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGA
AGAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGCAAGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGA
TCATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATCCTGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCG
GGTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCCTTGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAA
GGCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTGTACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGA
AGTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGGCAGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCC
AGCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTGCAGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGG
ACAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAGATCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGA
CGCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTGGCCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACAT
GATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAGACCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGA
GCTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTACTTCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCT
GTATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGGCACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCT
GGTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTCACTGACATCATCAAGTTTTTCAATGAACGTGCTGAGCATCACGA
TGCCCAGGAGATCCTGCGGATTGCCCGGGACCTCGTCCACAAGGTGCAGATGCTCATAGAGAACAAGTGAGCTGGGGCCAGGAGGCAGCA
GCCGTGCAGAGCCTGGGCTCCGGCAGGGAGAGGTGCAGGGGAGTCACCGCCCAGACCTCCCCAGCCACCAACCGACCCCACCTCTGTTCC
TAACAAAGCGGTTGTGAGCCTGGATCCGACTCCCGGCAGTGCTGACCCTGCAGGGCAAGTCAGGGGCCAGGATGCCCTCGGATCAGGGCC
GGGATGGGAGGGGTCAGCCTCAGGGAGCAGCTGCCTTGGGGGACACACCTACTCTGCTCCCCTCTCACACATCTGGGAGTAGCCCCACTG
CCACCTGCAGCCGCAGCCTGGACTGCTGCCCACGAGTGAACCTGGGGCCCCACAGGATTAACAGGGGCTATAGCGGCCTGGGCCCTACTC
AGCTGGGGTGGCAGAGGGCGAGAGGCTCTGTGCTGTGTCCCTTCTGAGGGTCCCTTTGCAGTCCCAGTATATTGTGCGTGCACCAGCCCC
AGCTGGAGCAACCAAAACTGCTTCTGGTTTAGGCACACGTCACGGGTGCGGGAGACCCGGGCACGGGAGACCCGGGCCGCCTTCAGGCCG
CTCCCCCGAGATTCTGGGGCAGTCGGAAGATGTGGGCCCTGGGTGGGAGCAGCCCACTTCAGCAGCACTGCCACTGCCTTTGGCCACCTG
AGGTGACCCCCAGGCCTCCCCGGCCTTGTACAGTGTACCTCTGTGTATCTGTACAGCCTCGCTCCTGCCACCCCACCCTTGCGTTCTGCA
TTAGGTACTTCCCTGAAAACCACGTGTAAGAAGTGATGCTTTTGCCAGTGGATGATCTGGAATGCGACCGGAGCACTTGCTCTGAGGAAT
CCCAGGGTGACTCTGTCGGGGAAGAATCCGGTCACAGCCTCCCCTCAGAGACAGGCCTCAGTTCGAGGGCAGCCCATTATCTGTCGCAGA
CATCTGCCATGTCCCTGAGACTGCGGGAGGCAGGGGATGCATGGGTGTCCCCATCTGTCCCTGGTGAGAAGCAAGGCTAGCTCTGCCTTC
CACATGCTTCTCAGGATGCCAAGAGGCCTAGGAACCCAGAAACCCCCTTGGAGGAGCTGTGTATGCGGGGGTGCCAGGAAGGGCATAGCT
CCTGCCCCCAGGCCTAGGCATGCTGCTTGCTCGGCCATCCCCACTTCCTCCTCTACCCCAACACATGCAGGCTAGGCCTTGCCCTGGAAC
ATGGAGGCCCTGCCCGGGGCTGGGGCCTAGTCCAGCAGCCACCAAAGTCTGGCAGACTTTCTGCATTTGAGAAACATGACAAAGGGCCCC
GCAGCCCTTCTGCACCCAGCACAGCCTGCCCAGCCCAGCCCTGCCCCCGGGCACTGCACAGCCTGTCTGGGGGCCAGACCACCCCATTGT
CCATCCTTGTTGTCCGTGAGTCCTTGGCCTCCACCAAGCACGTGTGGCCATTGTGTGCCTGCCTTAGTGACTCCGTGGTTTTGTGAGGAG

>72166_72166_11_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000542807_SGSM2_chr17_2281151_ENST00000426855_length(amino acids)=517AA_BP=399
MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLEEQKPGPQKNKDDYIPYPS
IDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI
LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKAR
QTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV
AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAAR

--------------------------------------------------------------
>72166_72166_12_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000542807_SGSM2_chr17_2281151_ENST00000574563_length(transcript)=1922nt_BP=1246nt
ACGTCGTTGGGACATCGCTGGGACCCCGGGCTCTGCAGCCACAACCATGTTTGGCCGGAAGCGCAGTGTCTCCTTTGGGGGCTTCGGATG
GATCGACAAGACCATGCTGGCAAGTCTGAAGGTCAAGAAGCAGGAGCTGGCCAACAGCTCGGATGCGACCCTCCCAGACCGGCCGCTCTC
CCCTCCTCTCACGGCACCTCCCACCATGAAGTCGTCGGAGTTCTTTGAGATGCTGGAGAAAATGCAGGGGATCAAGCTTGAAGAGCAGAA
GCCGGGACCCCAGAAGAACAAGGACGACTATATCCCATACCCCAGCATCGACGAGGTTGTGGAGAAGGGAGGCCCGTACCCTCAGGTCAT
CCTGCCACAGTTTGGGGGCTATTGGATCGAGGACCCGGAGAACGTGGGCACCCCAACATCGCTGGGGAGCAGCATCTGTGAGGAGGAGGA
AGAGGACAACCTCAGCCCCAACACATTTGGCTACAAGCTCGAGTGCAAGGGTGAAGCCAGGGCCTACCGGAGGCACTTCCTGGGGAAGGA
TCATCTAAACTTTTACTGTACCGGCAGCAGCCTGGGGAACTTGATCCTGTCCGTCAAGTGCGAGGAAGCAGAGGGGATCGAGTACCTCCG
GGTCATCCTTAGGTCCAAACTGAAGACGGTACATGAGCGGATCCCCTTGGCTGGACTGAGCAAGCTTCCCAGTGTCCCTCAGATTGCAAA
GGCTTTCTGTGATGATGCAGTGGGACTGAGATTCAATCCTGTCCTGTACCCCAAGGCCTCCCAAATGATTGTGTCCTATGATGAGCATGA
AGTCAACAACACATTCAAATTCGGAGTCATTTATCAAAAAGCCAGGCAGACCCTGGAGGAGGAGCTATTTGGGAACAATGAGGAGAGCCC
AGCTTTTAAGGAGTTCTTGGACCTGCTGGGGGACACGATCACACTGCAGGATTTCAAAGGTTTCCGAGGAGGCCTGGACGTGACCCACGG
ACAGACAGGGGTGGAATCAGTGTACACAACATTCCGGGACAGGGAGATCATGTTTCACGTTTCCACAAAGCTGCCATTTACCGACGGAGA
CGCCCAGCAGCTCCAGAGAAAGAGACACATTGGAAATGACATCGTGGCCATCATCTTCCAAGAGGAAAACACGCCGTTTGTCCCAGACAT
GATAGCCTCCAATTTCTTACATGCCTACATCGTCGTGCAGGTCGAGACCCCAGGCACAGAGACCCCATCCTACAAGATCCTGGACTCAGA
GCTGTTTGAGCTGATGCATCAGAATGGAGACTACACCCACTTCTACTTCTGTTATCGCTGGTTCCTGCTGGATTTTAAGAGAGAACTGCT
GTATGAGGATGTGTTTGCTGTGTGGGAGGTGATCTGGGCAGCCAGGCACATCTCATCGGAGCACTTTGTCCTGTTCATCGCCCTCGCCCT
GGTGGAGGCCTACCGAGAGATCATCCGTGACAACAACATGGACTTCACTGACATCATCAAGTTTTTCAATGGTACTTCCCTGAAAACCAC
GTGTAAGAAGTGATGCTTTTGCCAGTGGATGATCTGGAATGCGACCGGAGCACTTGCTCTGAGGAATCCCAGGGTGACTCTGTCGGGGAA
GAATCCGGTCACAGCCTCCCCTCAGAGACAGGCCTCAGTTCGAGGGCAGCCCATTATCTGTCGCAGACATCTGCCATGTCCCTGAGACTG
CGGGAGGCAGGGGATGCATGGGTGTCCCCATCTGTCCCTGGTGAGAAGCAAGGCTAGCTCTGCCTTCCACATGCTTCTCAGGATGCCAAG
AGGCCTAGGAACCCAGAAACCCCCTTGGAGGAGCTGTGTATGCGGGGGTGCCAGGAAGGGCATAGCTCCTGCCCCCAGGCCTAGGCATGC

>72166_72166_12_RAP1GAP2-SGSM2_RAP1GAP2_chr17_2901670_ENST00000542807_SGSM2_chr17_2281151_ENST00000574563_length(amino acids)=498AA_BP=399
MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLEEQKPGPQKNKDDYIPYPS
IDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI
LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKAR
QTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV
AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAAR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RAP1GAP2-SGSM2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for RAP1GAP2-SGSM2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for RAP1GAP2-SGSM2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source