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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:RASA3-KCNG2 (FusionGDB2 ID:72397)

Fusion Gene Summary for RASA3-KCNG2

Fusion gene summary

Fusion gene information	Fusion gene name: RASA3-KCNG2
	Fusion gene ID: 72397
		Hgene	Tgene
	Gene symbol	RASA3	KCNG2
	Gene ID	22821	26251
	Gene name	RAS p21 protein activator 3	potassium voltage-gated channel modifier subfamily G member 2
	Synonyms	GAP1IP4BP\|GAPIII	KCNF2\|KV6.2
	Cytomap	13q34	18q23
	Type of gene	protein-coding	protein-coding
	Description	ras GTPase-activating protein 3GTPase activating protein IIIGTPase-activating protein 1 family, inositol 1,3,4,5-tetrakisphosphate-binding proteinIns(1,3,4,5)P4-binding proteinins P4-binding protein	potassium voltage-gated channel subfamily G member 2cardiac potassium channel subunitpotassium channel, voltage gated modifier subfamily G, member 2potassium voltage-gated channel, subfamily G, member 2voltage-gated potassium channel subunit Kv6.2
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000334062, ENST00000389544, ENST00000542651,	ENST00000590307, ENST00000316249,
Fusion gene scores	* DoF score	4 X 5 X 4=80	1 X 2 X 1=2
	# samples	5	2
	** MAII score	log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(2/2*10)=3.32192809488736
Context	PubMed: RASA3 [Title/Abstract] AND KCNG2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	RASA3(114817527)-KCNG2(77659040), # samples:3
Anticipated loss of major functional domain due to fusion event.	RASA3-KCNG2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. RASA3-KCNG2 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF. RASA3-KCNG2 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across RASA3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across KCNG2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LGG	TCGA-FG-A711-01A	RASA3	chr13	114817527	-	KCNG2	chr18	77659040	+
ChimerDB4	LGG	TCGA-FG-A711	RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+
ChimerDB4	LGG	TCGA-FG-A711	RASA3	chr13	114817527	-	KCNG2	chr18	77659040	+

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Fusion Gene ORF analysis for RASA3-KCNG2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000334062	ENST00000590307	RASA3	chr13	114817527	-	KCNG2	chr18	77659040	+
5CDS-3UTR	ENST00000334062	ENST00000590307	RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+
5CDS-3UTR	ENST00000389544	ENST00000590307	RASA3	chr13	114817527	-	KCNG2	chr18	77659040	+
5CDS-3UTR	ENST00000389544	ENST00000590307	RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+
5CDS-3UTR	ENST00000542651	ENST00000590307	RASA3	chr13	114817527	-	KCNG2	chr18	77659040	+
5CDS-3UTR	ENST00000542651	ENST00000590307	RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+
Frame-shift	ENST00000334062	ENST00000316249	RASA3	chr13	114817527	-	KCNG2	chr18	77659040	+
Frame-shift	ENST00000334062	ENST00000316249	RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+
Frame-shift	ENST00000389544	ENST00000316249	RASA3	chr13	114817527	-	KCNG2	chr18	77659040	+
Frame-shift	ENST00000389544	ENST00000316249	RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+
In-frame	ENST00000542651	ENST00000316249	RASA3	chr13	114817527	-	KCNG2	chr18	77659040	+
In-frame	ENST00000542651	ENST00000316249	RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

ENST00000542651

RASA3

chr13

114817527

ENST00000316249

KCNG2

chr18

77659040

1117

340

367

1116

250

ENST00000542651

RASA3

chr13

114817526

ENST00000316249

KCNG2

chr18

77659039

1117

340

367

1116

250

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000542651	ENST00000316249	RASA3	chr13	114817527	-	KCNG2	chr18	77659040	+	0.46250278	0.5374972
ENST00000542651	ENST00000316249	RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+	0.46250278	0.5374972

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Fusion Genomic Features for RASA3-KCNG2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+	7.36E-05	0.9999263
RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+	7.36E-05	0.9999263
RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+	7.36E-05	0.9999263
RASA3	chr13	114817526	-	KCNG2	chr18	77659039	+	7.36E-05	0.9999263

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RASA3-KCNG2

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:114817527/chr18:77659040)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

357_377

208

467.0

Intramembrane

Pore-forming%3B Name%3DSegment H5

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

357_377

208

467.0

Intramembrane

Pore-forming%3B Name%3DSegment H5

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

369_374

208

467.0

Motif

Selectivity filter

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

369_374

208

467.0

Motif

Selectivity filter

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

309_321

208

467.0

Topological domain

Cytoplasmic

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

406_466

208

467.0

Topological domain

Cytoplasmic

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

309_321

208

467.0

Topological domain

Cytoplasmic

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

406_466

208

467.0

Topological domain

Cytoplasmic

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

218_238

208

467.0

Transmembrane

Helical%3B Name%3DSegment S2

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

253_273

208

467.0

Transmembrane

Helical%3B Name%3DSegment S3

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

288_308

208

467.0

Transmembrane

Helical%3B Voltage-sensor%3B Name%3DSegment S4

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

322_342

208

467.0

Transmembrane

Helical%3B Name%3DSegment S5

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

385_405

208

467.0

Transmembrane

Helical%3B Name%3DSegment S6

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

218_238

208

467.0

Transmembrane

Helical%3B Name%3DSegment S2

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

253_273

208

467.0

Transmembrane

Helical%3B Name%3DSegment S3

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

288_308

208

467.0

Transmembrane

Helical%3B Voltage-sensor%3B Name%3DSegment S4

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

322_342

208

467.0

Transmembrane

Helical%3B Name%3DSegment S5

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

385_405

208

467.0

Transmembrane

Helical%3B Name%3DSegment S6

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

RASA3

chr13:114817526

chr18:77659039

ENST00000334062

123_263

835.0

Domain

C2 2

Hgene

RASA3

chr13:114817526

chr18:77659039

ENST00000334062

1_112

835.0

Domain

C2 1

Hgene

RASA3

chr13:114817526

chr18:77659039

ENST00000334062

330_524

835.0

Domain

Ras-GAP

Hgene

RASA3

chr13:114817526

chr18:77659039

ENST00000334062

576_677

835.0

Domain

Hgene

RASA3

chr13:114817527

chr18:77659040

ENST00000334062

123_263

835.0

Domain

C2 2

Hgene

RASA3

chr13:114817527

chr18:77659040

ENST00000334062

1_112

835.0

Domain

C2 1

Hgene

RASA3

chr13:114817527

chr18:77659040

ENST00000334062

330_524

835.0

Domain

Ras-GAP

Hgene

RASA3

chr13:114817527

chr18:77659040

ENST00000334062

576_677

835.0

Domain

Hgene

RASA3

chr13:114817526

chr18:77659039

ENST00000334062

679_715

835.0

Zinc finger

Btk-type

Hgene

RASA3

chr13:114817527

chr18:77659040

ENST00000334062

679_715

835.0

Zinc finger

Btk-type

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

9_13

208

467.0

Compositional bias

Note=Poly-Gly

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

9_13

208

467.0

Compositional bias

Note=Poly-Gly

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

1_177

208

467.0

Topological domain

Cytoplasmic

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

1_177

208

467.0

Topological domain

Cytoplasmic

Tgene

KCNG2

chr13:114817526

chr18:77659039

ENST00000316249

178_198

208

467.0

Transmembrane

Helical%3B Name%3DSegment S1

Tgene

KCNG2

chr13:114817527

chr18:77659040

ENST00000316249

178_198

208

467.0

Transmembrane

Helical%3B Name%3DSegment S1

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Fusion Gene Sequence for RASA3-KCNG2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>72397_72397_1_RASA3-KCNG2_RASA3_chr13_114817526_ENST00000542651_KCNG2_chr18_77659039_ENST00000316249_length(transcript)=1117nt_BP=340nt
GGCCTGAGCTGCCCGGGCTCGGCGCGCGCTTGGGGCGAGGCTCGGCGGGCGCGGACGCGCAGCATGGCGGTGGAGGACGAGGGGCTCCGG
GTCTTCCAGAGCGTGAAGATCAAGATCGGTGAAGCCAAAAACCTTCCCTCTTACCCGGGGCCGAGCAAGATGAGGGATTGCTACTGCACG
GTGAACCTGGACCAGGAGGAGGTTTTCAGGACCAAAATTGTGGAAAAGTCACTCTGCCCGTTTTACGGAGAAGACTTTTACTGTGAAATT
CCTCGGAGCTTTCGTCACCTGTCCTTCTACATTTTCGATAGAGACGTTTTCCGGAGGGATTCCATCATAGGGCGAGTGCTCCCCCAAGTG
CCGCAGCCTGTTCGTGCTGGAGACCGTGTGCGTGGCCTGGTTCTCCTTCGAGTTCCTGCTGCGCTCCCTGCAGGCCGAGAGCAAGTGCGC
CTTCCTGCGCGCGCCACTCAACATCATTGACATCCTGGCGCTCCTGCCGTTCTACGTGTCGCTGCTGCTGGGGCTGGCGGCAGGCCCGGG
CGGGACCAAGCTCCTGGAGCGCGCGGGGCTGGTGCTGCGGCTGCTGCGTGCGCTGCGCGTGCTCTACGTGATGCGCCTGGCGCGCCACTC
GCTGGGGCTGCGTTCGCTGGGCCTGACCATGCGCCGCTGCGCGCGCGAGTTCGGGCTGCTGCTGCTGTTCCTCTGCGTGGCCATGGCGCT
CTTCGCGCCACTGGTGCACCTGGCCGAGCGCGAGCTGGGCGCGCGCCGCGACTTCTCCAGCGTGCCCGCCAGCTATTGGTGGGCCGTCAT
CTCCATGACCACCGTGGGCTACGGCGACATGGTCCCGCGCAGCCTGCCCGGGCAGGTGGTGGCGCTCAGCAGCATCCTCAGCGGCATCCT
GCTCATGGCCTTCCCGGTCACCTCCATCTTCCACACCTTTTCGCGCTCCTACTCCGAGCTCAAGGAGCAGCAGCAGCGCGCGGCCAGCCC
CGAGCCGGCCCTGCAGGAGGACAGCACGCACTCGGCCACAGCCACCGAGGACAGCTCGCAGGGCCCCGACAGCGCGGGCCTGGCCGACGA

>72397_72397_1_RASA3-KCNG2_RASA3_chr13_114817526_ENST00000542651_KCNG2_chr18_77659039_ENST00000316249_length(amino acids)=250AA_BP=
MFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLG
LRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLM

--------------------------------------------------------------
>72397_72397_2_RASA3-KCNG2_RASA3_chr13_114817527_ENST00000542651_KCNG2_chr18_77659040_ENST00000316249_length(transcript)=1117nt_BP=340nt
GGCCTGAGCTGCCCGGGCTCGGCGCGCGCTTGGGGCGAGGCTCGGCGGGCGCGGACGCGCAGCATGGCGGTGGAGGACGAGGGGCTCCGG
GTCTTCCAGAGCGTGAAGATCAAGATCGGTGAAGCCAAAAACCTTCCCTCTTACCCGGGGCCGAGCAAGATGAGGGATTGCTACTGCACG
GTGAACCTGGACCAGGAGGAGGTTTTCAGGACCAAAATTGTGGAAAAGTCACTCTGCCCGTTTTACGGAGAAGACTTTTACTGTGAAATT
CCTCGGAGCTTTCGTCACCTGTCCTTCTACATTTTCGATAGAGACGTTTTCCGGAGGGATTCCATCATAGGGCGAGTGCTCCCCCAAGTG
CCGCAGCCTGTTCGTGCTGGAGACCGTGTGCGTGGCCTGGTTCTCCTTCGAGTTCCTGCTGCGCTCCCTGCAGGCCGAGAGCAAGTGCGC
CTTCCTGCGCGCGCCACTCAACATCATTGACATCCTGGCGCTCCTGCCGTTCTACGTGTCGCTGCTGCTGGGGCTGGCGGCAGGCCCGGG
CGGGACCAAGCTCCTGGAGCGCGCGGGGCTGGTGCTGCGGCTGCTGCGTGCGCTGCGCGTGCTCTACGTGATGCGCCTGGCGCGCCACTC
GCTGGGGCTGCGTTCGCTGGGCCTGACCATGCGCCGCTGCGCGCGCGAGTTCGGGCTGCTGCTGCTGTTCCTCTGCGTGGCCATGGCGCT
CTTCGCGCCACTGGTGCACCTGGCCGAGCGCGAGCTGGGCGCGCGCCGCGACTTCTCCAGCGTGCCCGCCAGCTATTGGTGGGCCGTCAT
CTCCATGACCACCGTGGGCTACGGCGACATGGTCCCGCGCAGCCTGCCCGGGCAGGTGGTGGCGCTCAGCAGCATCCTCAGCGGCATCCT
GCTCATGGCCTTCCCGGTCACCTCCATCTTCCACACCTTTTCGCGCTCCTACTCCGAGCTCAAGGAGCAGCAGCAGCGCGCGGCCAGCCC
CGAGCCGGCCCTGCAGGAGGACAGCACGCACTCGGCCACAGCCACCGAGGACAGCTCGCAGGGCCCCGACAGCGCGGGCCTGGCCGACGA

>72397_72397_2_RASA3-KCNG2_RASA3_chr13_114817527_ENST00000542651_KCNG2_chr18_77659040_ENST00000316249_length(amino acids)=250AA_BP=
MFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLG
LRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLM

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RASA3-KCNG2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for RASA3-KCNG2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for RASA3-KCNG2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source