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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:RASA4-ATXN7L1 (FusionGDB2 ID:72400) |
Fusion Gene Summary for RASA4-ATXN7L1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RASA4-ATXN7L1 | Fusion gene ID: 72400 | Hgene | Tgene | Gene symbol | RASA4 | ATXN7L1 | Gene ID | 10156 | 222255 |
| Gene name | RAS p21 protein activator 4 | ataxin 7 like 1 | |
| Synonyms | CAPRI|GAPL | ATXN7L4 | |
| Cytomap | 7q22.1 | 7q22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ras GTPase-activating protein 4Ca2+-promoted Ras inactivatorcalcium-promoted Ras inactivatorrasGAP-activating-like protein 2 | ataxin-7-like protein 1ataxin 7-like 4ataxin-7-like protein 4 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | Q9ULK2 | |
| Ensembl transtripts involved in fusion gene | ENST00000262940, ENST00000449970, ENST00000461209, ENST00000462172, ENST00000521822, | ENST00000318724, ENST00000388807, ENST00000472910, ENST00000478915, ENST00000419735, ENST00000477775, | |
| Fusion gene scores | * DoF score | 7 X 7 X 6=294 | 12 X 8 X 5=480 |
| # samples | 7 | 12 | |
| ** MAII score | log2(7/294*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/480*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RASA4 [Title/Abstract] AND ATXN7L1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | RASA4(102232732)-ATXN7L1(105251050), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | RASA4 | GO:0034260 | negative regulation of GTPase activity | 12845332 |
| Fusion gene breakpoints across RASA4 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across ATXN7L1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | OV | TCGA-61-1910-01A | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
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Fusion Gene ORF analysis for RASA4-ATXN7L1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000262940 | ENST00000318724 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000262940 | ENST00000388807 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000262940 | ENST00000472910 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000262940 | ENST00000478915 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000449970 | ENST00000318724 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000449970 | ENST00000388807 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000449970 | ENST00000472910 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000449970 | ENST00000478915 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000461209 | ENST00000318724 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000461209 | ENST00000388807 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000461209 | ENST00000472910 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000461209 | ENST00000478915 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000462172 | ENST00000318724 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000462172 | ENST00000388807 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000462172 | ENST00000472910 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5CDS-intron | ENST00000462172 | ENST00000478915 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5UTR-3CDS | ENST00000521822 | ENST00000419735 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5UTR-3CDS | ENST00000521822 | ENST00000477775 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5UTR-intron | ENST00000521822 | ENST00000318724 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5UTR-intron | ENST00000521822 | ENST00000388807 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5UTR-intron | ENST00000521822 | ENST00000472910 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| 5UTR-intron | ENST00000521822 | ENST00000478915 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| Frame-shift | ENST00000461209 | ENST00000419735 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| Frame-shift | ENST00000461209 | ENST00000477775 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| In-frame | ENST00000262940 | ENST00000419735 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| In-frame | ENST00000262940 | ENST00000477775 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| In-frame | ENST00000449970 | ENST00000419735 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| In-frame | ENST00000449970 | ENST00000477775 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| In-frame | ENST00000462172 | ENST00000419735 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| In-frame | ENST00000462172 | ENST00000477775 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000262940 | RASA4 | chr7 | 102232732 | - | ENST00000419735 | ATXN7L1 | chr7 | 105251050 | - | 4797 | 1898 | 68 | 2011 | 647 |
| ENST00000262940 | RASA4 | chr7 | 102232732 | - | ENST00000477775 | ATXN7L1 | chr7 | 105251050 | - | 2096 | 1898 | 68 | 2014 | 648 |
| ENST00000449970 | RASA4 | chr7 | 102232732 | - | ENST00000419735 | ATXN7L1 | chr7 | 105251050 | - | 4796 | 1897 | 67 | 2010 | 647 |
| ENST00000449970 | RASA4 | chr7 | 102232732 | - | ENST00000477775 | ATXN7L1 | chr7 | 105251050 | - | 2095 | 1897 | 67 | 2013 | 648 |
| ENST00000462172 | RASA4 | chr7 | 102232732 | - | ENST00000419735 | ATXN7L1 | chr7 | 105251050 | - | 4871 | 1972 | 151 | 2085 | 644 |
| ENST00000462172 | RASA4 | chr7 | 102232732 | - | ENST00000477775 | ATXN7L1 | chr7 | 105251050 | - | 2170 | 1972 | 151 | 2088 | 645 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000262940 | ENST00000419735 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - | 0.001855333 | 0.9981446 |
| ENST00000262940 | ENST00000477775 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - | 0.016322678 | 0.98367727 |
| ENST00000449970 | ENST00000419735 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - | 0.001858909 | 0.99814105 |
| ENST00000449970 | ENST00000477775 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - | 0.016321843 | 0.9836782 |
| ENST00000462172 | ENST00000419735 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - | 0.001720916 | 0.9982791 |
| ENST00000462172 | ENST00000477775 | RASA4 | chr7 | 102232732 | - | ATXN7L1 | chr7 | 105251050 | - | 0.016579194 | 0.9834208 |
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Fusion Genomic Features for RASA4-ATXN7L1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for RASA4-ATXN7L1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:102232732/chr7:105251050) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | ATXN7L1 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000262940 | - | 16 | 21 | 500_503 | 610 | 804.0 | Compositional bias | Note=Poly-Leu |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000449970 | - | 16 | 20 | 500_503 | 610 | 758.0 | Compositional bias | Note=Poly-Leu |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000262940 | - | 16 | 21 | 116_232 | 610 | 804.0 | Domain | C2 2 |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000262940 | - | 16 | 21 | 1_105 | 610 | 804.0 | Domain | C2 1 |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000262940 | - | 16 | 21 | 302_512 | 610 | 804.0 | Domain | Ras-GAP |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000449970 | - | 16 | 20 | 116_232 | 610 | 758.0 | Domain | C2 2 |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000449970 | - | 16 | 20 | 1_105 | 610 | 758.0 | Domain | C2 1 |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000449970 | - | 16 | 20 | 302_512 | 610 | 758.0 | Domain | Ras-GAP |
| Tgene | ATXN7L1 | chr7:102232732 | chr7:105251050 | ENST00000318724 | 0 | 4 | 364_417 | 0 | 147.0 | Compositional bias | Note=Ser-rich | |
| Tgene | ATXN7L1 | chr7:102232732 | chr7:105251050 | ENST00000318724 | 0 | 4 | 536_847 | 0 | 147.0 | Compositional bias | Note=Ser-rich | |
| Tgene | ATXN7L1 | chr7:102232732 | chr7:105251050 | ENST00000318724 | 0 | 4 | 284_351 | 0 | 147.0 | Domain | SCA7 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000262940 | - | 16 | 21 | 566_673 | 610 | 804.0 | Domain | PH |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000449970 | - | 16 | 20 | 566_673 | 610 | 758.0 | Domain | PH |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000262940 | - | 16 | 21 | 675_711 | 610 | 804.0 | Zinc finger | Btk-type |
| Hgene | RASA4 | chr7:102232732 | chr7:105251050 | ENST00000449970 | - | 16 | 20 | 675_711 | 610 | 758.0 | Zinc finger | Btk-type |
| Tgene | ATXN7L1 | chr7:102232732 | chr7:105251050 | ENST00000419735 | 9 | 12 | 364_417 | 824 | 862.0 | Compositional bias | Note=Ser-rich | |
| Tgene | ATXN7L1 | chr7:102232732 | chr7:105251050 | ENST00000419735 | 9 | 12 | 536_847 | 824 | 862.0 | Compositional bias | Note=Ser-rich | |
| Tgene | ATXN7L1 | chr7:102232732 | chr7:105251050 | ENST00000477775 | 7 | 10 | 364_417 | 700 | 739.0 | Compositional bias | Note=Ser-rich | |
| Tgene | ATXN7L1 | chr7:102232732 | chr7:105251050 | ENST00000477775 | 7 | 10 | 536_847 | 700 | 739.0 | Compositional bias | Note=Ser-rich | |
| Tgene | ATXN7L1 | chr7:102232732 | chr7:105251050 | ENST00000419735 | 9 | 12 | 284_351 | 824 | 862.0 | Domain | SCA7 | |
| Tgene | ATXN7L1 | chr7:102232732 | chr7:105251050 | ENST00000477775 | 7 | 10 | 284_351 | 700 | 739.0 | Domain | SCA7 |
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Fusion Gene Sequence for RASA4-ATXN7L1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >72400_72400_1_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000262940_ATXN7L1_chr7_105251050_ENST00000419735_length(transcript)=4797nt_BP=1898nt CAGTCCAGCGCCCGCCGCCCGCCACCCCGGACCCCGGTGTCTGGCTTCCCCCGAGCCGGGACCCCGCGATGGCCAAGCGCAGCTCGCTGT ACATCCGCATCGTGGAGGGGAAGAACCTTCCCGCCAAGGACATCACTGGCAGCAGCGACCCCTACTGCATCGTGAAGGTGGACAATGAGC CCATCATCAGGACAGCCACAGTGTGGAAGACCCTGTGCCCCTTCTGGGGTGAGGAGTACCAAGTGCACCTGCCGCCCACCTTCCACGCTG TGGCTTTCTATGTCATGGATGAGGATGCCCTCAGCCGGGACGACGTTATCGGAAAGGTCTGCCTTACAAGGGACACCATAGCCTCTCACC CTAAGGGTTTCAGCGGGTGGGCCCACCTGACGGAGGTCGACCCCGATGAGGAGGTGCAGGGCGAGATCCACCTGCGGCTGGAAGTGTGGC CAGGGGCCCGGGCCTGCCGGCTACGCTGCTCTGTGCTGGAGGCCAGGGATCTGGCCCCAAAGGACCGCAATGGCACATCTGACCCCTTCG TCCGAGTGCGCTACAAGGGCCGGACACGGGAGACCTCGATCGTGAAGAAGTCATGCTACCCACGCTGGAATGAGACGTTTGAATTTGAGC TGCAGGAGGGGGCCATGGAGGCGCTGTGCGTGGAGGCCTGGGACTGGGACCTTGTCAGCCGAAACGACTTCCTGGGCAAAGTGGTGATTG ATGTCCAGAGACTGCGGGTGGTGCAGCAGGAGGAGGGCTGGTTCCGGCTGCAGCCCGACCAGTCCAAGAGCCGGCGGCATGACGAGGGCA ACCTGGGCTCCTTGCAGCTGGAGGTGCGGCTGCGGGACGAGACGGTGCTGCCCTCCAGCTACTACCAGCCACTGGTGCACCTGCTGTGCC ACGAGGTCAAGCTGGGCATGCAGGGCCCAGGGCAGCTGATCCCACTCATCGAGGAGACAACCAGCACCGAGTGTCGCCAGGACGTGGCCA CGAACCTGCTCAAGCTCTTCCTGGGGCAGGGGCTGGCCAAGGACTTCCTGGACCTGCTCTTCCAGCTGGAGCTGAGTCGCACCAGTGAGA CCAACACCCTGTTCCGGAGCAACTCTCTGGCCTCAAAGTCCATGGAGTCTTTTCTGAAGGTGGCCGGGATGCAGTACCTGCACGGCGTCC TGGGCCCCATCATCAACAAGGTGTTTGAGGAGAAGAAGTACGTGGAGCTGGACCCCAGCAAAGTGGAAGTTAAGGATGTAGGGTGCTCCG GGCTGCACCGCCCGCAGACCGAGGCCGAGGTGCTGGAGCAGAGCGCGCAGACGCTGCGCGCCCACCTGGGGGCCCTGCTGAGCGCGCTCA GCCGCTCGGTTCGCGCGTGCCCCGCCGTGGTGCGCGCCACCTTCCGCCAGCTCTTCCGGCGCGTGCGCGAGCGCTTCCCCGGCGCCCAGC ACGAGAATGTACCGTTCATCGCCGTCACCAGCTTCCTGTGCCTGCGCTTCTTCTCTCCCGCCATCATGTCGCCCAAGCTCTTCCACCTGC GGGAGCGCCACGCGGACGCCCGCACCAGCCGCACCCTGCTCCTGTTGGCCAAGGCAGTCCAGAACGTGGGCAACATGGACACGCCGGCTT CCAGGGCCAAGGAGGCTTGGATGGAGCCGCTGCAGCCCACCGTGCGCCAGGGCGTGGCGCAGCTGAAGGACTTCATCACCAAGCTCGTGG ACATCGAGGAGAAGGACGAGCTGGACCTGCAGCGGACGCTGAGTTTGCAGGCGCCACCTGTGAAGGAGGGGCCACTCTTCATCCACAGGA CCAAGGGCAAGGGCCCCCTCATGTCCTCCTCCTTCAAGAAGCTCTACTTCTCCCTCACTACCGAGGCCCTCAGCTTCGCGAAGACGCCCA GCTCCAAGGTTGGGAAAAATAGCAGCCTAGCTTTGTCACAATCCAGTCCTTCAAGTATATCCAGCCCAGGACACAGCCGACAGAACACAA ACAGAACGGGCAGGATAAGGACTCTTCCATAACAAGACTATGAAGCCACTTCCACATCAATTCCAGGCCACCTAATCCCATCCGAGGAGG CCATGGGGAGGAGGAGGGAGGGGAGTGGGCTGGGGGGAGAGTCTGTTTTCTGTGCACTCCCTGTGACTCTGGCCTTTCTTCTTCTTTTTT TAATTGACCAATTTTTAGTTAAAAAGGCAAAAGAAGGTGAATTTGAGATTTACAGAAAACAGTTCCAGTGTTTGGTTTCCGCTGTCTTTC CTTTCATTTGCCATGTTTTTACATTCTTCCAAATTTGGGGTCACTCCCCTAGCTCCTGATGCTGCTACTGTACCATCCTTTTGCTCCAGC CATGAGAGCAGACATTGCAGAATGTTGGTTCCAGGTTGGCATGCTCTGAAGCTCTTGAACTGTAGCACAGGCAGAGCCCTTTTTCTTCCT GTCATCTCCACCCGATTCCTTCCATCCCTACGTCTACCACTCTCTGGGTCCTCACTGGTCTTCAAAGGACCTGGCTCTCATAGGATCCCC TCAGGATTGTGTGCAGGGAGAGGGGGCTTTGCTGGGGAGGAGCTGGGAGTGGAGAGTTGGAGGGTGGGTGGGGTTCCCTCATCCAGTTTC CACAGCCCACCATGGCTGGAGCCAAATGCTAGAAGCGAGATTGAGAACAGTGGCCGTTTAGTGATGTGGTTTACCTAATACCACTGTCCA GCTGTGCAGCTCAGAAAGGATAAACCAGTCAGGGACAGGGGCCAGAACAGGTTTGGGAAGGTGGCAGCAAGCAGAGCATGGTGGGTAGGA GATGATCCCTAAAAAAACTGGAGACTGTGGTGGTCTGAGCTGGTCAGGAATCTGCAGAATCCCTTCCAGGAATCAGTGTGCCAGTGCCCA CAGCAGGGTGAGCTAGGAGGGAGAAATCCCAGGAAAAAGGTCGTGAGAACCCAGAAAGCCACTCCATGAGGAGGCACGGTGACCACAGCT GCTAAAGGTTCTTAGGCTGCCTTCCTGGGCTAGGAAGAGCCCCCCAGGGAGAGCTTCCACAAAAGGGTATGTGTCAAACCTTTTGTCAGA ATAAATAATAGCATTTCCCACCCACCCCCATGCCCTGGGCCACAGGGACTTGGTGGGATCAGCACACCCATGGATCAGCTTTTGCTGTCT TAGAGACAGCCATCCCCATGAAGGAATGGTAAGGACAGCCACTGCTCAGTGAAGAACAGCCATTTGGAAGAGCCACGCTGGAGCCCTGCA GCCATAGAACTATTCACACTGGAGTTTTAAAAGAAACAGCAATACCATAAGCTCTAGTAGGGAATCATAATCAGGAAAGGAATTCACAAC ATAAAATAGGTGTTCTGTGCTATTAATCATGTAACTTTGTATATGATGTATAGCAAAGATACTGGGAGGTTTTGTTTCATCCTTAAATCA GAAATGAATGCTAGTTTCATAGCTGGGCAGAACCCTCATCCCCACCCCAAAGTTTTCCTTTTCTTTCCCGTTCCCCCAACCCAAAGATCA GACTACTGTTAAGTTTCACCACACAATTGGAATTGCAAAGACGGGAGGCAAATGGAGTGATTTTCATCAATGGAATTGCACTGACAGTGA GTGTTTCTTATAGGATTACTAAATTTTTTAATATAAAATGATTTGTTTAAAAATCAGGAGTTGATATTAAGTACCAGGACATTAGTTCGG ATGATTTCATTTTTATTTCTACAGTGTTAAAAGTGCACTTATATGCTGGTTTATTTACGTCTTGGGAAAAGAGACTGCAAATTGAAGGGA TGATTGTTACTTTTTCTTTTTTTAAAAAAAAAAGGTTAAGGAGATTTTAAGACTTATAAATGTTTAAGAAATTATAAACAAGGTTAGACC CTTTGAAAAAAAGTTTAGAAGATATTCTTAAAGTAAATTTTTATAGTGTTAATTTTGTAATAATTTATGTTTTACTATATTACAGAGCTA ACTGACCAGAATAGTTTCAGAAACAATATGAAACTTAGGAAAGTTTAAGCAATGTTTATATTTTTAAAATGTTCTTTGAATTATGTTTTT ATTGTACATTTCTTCAGACTGAAAAGTATGTACATATCTTTGTTATTTTTGCACAATTTTGTCTTGTTCGGTTTCAGAGGTCTGTTGTTT TTTATAATTTATTTTGAGTTGTAAAACTTGCAGGAGTAAAAACAAAAAACAAAATCTCCACAACAAAATAACCCTCTGATTTATAAACTC TTATAGTCAAAGAGGGAAAACAAAGGTTGAGAGATTAAGTGGCTGCTTCTGAGAAATAATGTCTCAAGGACTAAAGGAGCAATTCAATAG GTTTAGACATTGTAGCTCTCTACATCTTGAATTGGAAGCTGGAATAAAGAGCCCCCACCCCCCCCCCCACCCTCATCGAATGCTGCTTAC TTTGTCAAAAGACTGGCTATGACCAAGGTGAGGATATTTCTGGAAAACTGGGCAAAAAGGGAAAGCCCACAGTATTCTTCCTTGGCAGTC AACCACAGGTTTACTTTACAATGATGTATTAAAAACTTGCAGCTTGAAAAATGGAATGCAAATAAAAGGTTCTCTTTGGGTTTGTCTTAA TGGAGTTAAACTGGAGCAGCCTATAAAACATTTTTAGGGTGATGTCCTCTGGGTCCTTCTGTTCTGCACACCCACTCAGTCTTCTCTCCC AGCCCCTTGACTGCACACACCCCTCTTTGCCTGAAGATCTCCTGACTTGTCGCCAGCCATAGAGGCTCGAAAGCTCTGGTTGTGAAGCAT >72400_72400_1_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000262940_ATXN7L1_chr7_105251050_ENST00000419735_length(amino acids)=647AA_BP=610 MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHAVAFYVMDEDALSRDDVIGKVCLT RDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRW NETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLRDETVLPSSYYQ PLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAG MQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPAVVRATFRQLFRRVR ERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLK DFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKVGKNSSLALSQSSPSSISSP -------------------------------------------------------------- >72400_72400_2_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000262940_ATXN7L1_chr7_105251050_ENST00000477775_length(transcript)=2096nt_BP=1898nt CAGTCCAGCGCCCGCCGCCCGCCACCCCGGACCCCGGTGTCTGGCTTCCCCCGAGCCGGGACCCCGCGATGGCCAAGCGCAGCTCGCTGT ACATCCGCATCGTGGAGGGGAAGAACCTTCCCGCCAAGGACATCACTGGCAGCAGCGACCCCTACTGCATCGTGAAGGTGGACAATGAGC CCATCATCAGGACAGCCACAGTGTGGAAGACCCTGTGCCCCTTCTGGGGTGAGGAGTACCAAGTGCACCTGCCGCCCACCTTCCACGCTG TGGCTTTCTATGTCATGGATGAGGATGCCCTCAGCCGGGACGACGTTATCGGAAAGGTCTGCCTTACAAGGGACACCATAGCCTCTCACC CTAAGGGTTTCAGCGGGTGGGCCCACCTGACGGAGGTCGACCCCGATGAGGAGGTGCAGGGCGAGATCCACCTGCGGCTGGAAGTGTGGC CAGGGGCCCGGGCCTGCCGGCTACGCTGCTCTGTGCTGGAGGCCAGGGATCTGGCCCCAAAGGACCGCAATGGCACATCTGACCCCTTCG TCCGAGTGCGCTACAAGGGCCGGACACGGGAGACCTCGATCGTGAAGAAGTCATGCTACCCACGCTGGAATGAGACGTTTGAATTTGAGC TGCAGGAGGGGGCCATGGAGGCGCTGTGCGTGGAGGCCTGGGACTGGGACCTTGTCAGCCGAAACGACTTCCTGGGCAAAGTGGTGATTG ATGTCCAGAGACTGCGGGTGGTGCAGCAGGAGGAGGGCTGGTTCCGGCTGCAGCCCGACCAGTCCAAGAGCCGGCGGCATGACGAGGGCA ACCTGGGCTCCTTGCAGCTGGAGGTGCGGCTGCGGGACGAGACGGTGCTGCCCTCCAGCTACTACCAGCCACTGGTGCACCTGCTGTGCC ACGAGGTCAAGCTGGGCATGCAGGGCCCAGGGCAGCTGATCCCACTCATCGAGGAGACAACCAGCACCGAGTGTCGCCAGGACGTGGCCA CGAACCTGCTCAAGCTCTTCCTGGGGCAGGGGCTGGCCAAGGACTTCCTGGACCTGCTCTTCCAGCTGGAGCTGAGTCGCACCAGTGAGA CCAACACCCTGTTCCGGAGCAACTCTCTGGCCTCAAAGTCCATGGAGTCTTTTCTGAAGGTGGCCGGGATGCAGTACCTGCACGGCGTCC TGGGCCCCATCATCAACAAGGTGTTTGAGGAGAAGAAGTACGTGGAGCTGGACCCCAGCAAAGTGGAAGTTAAGGATGTAGGGTGCTCCG GGCTGCACCGCCCGCAGACCGAGGCCGAGGTGCTGGAGCAGAGCGCGCAGACGCTGCGCGCCCACCTGGGGGCCCTGCTGAGCGCGCTCA GCCGCTCGGTTCGCGCGTGCCCCGCCGTGGTGCGCGCCACCTTCCGCCAGCTCTTCCGGCGCGTGCGCGAGCGCTTCCCCGGCGCCCAGC ACGAGAATGTACCGTTCATCGCCGTCACCAGCTTCCTGTGCCTGCGCTTCTTCTCTCCCGCCATCATGTCGCCCAAGCTCTTCCACCTGC GGGAGCGCCACGCGGACGCCCGCACCAGCCGCACCCTGCTCCTGTTGGCCAAGGCAGTCCAGAACGTGGGCAACATGGACACGCCGGCTT CCAGGGCCAAGGAGGCTTGGATGGAGCCGCTGCAGCCCACCGTGCGCCAGGGCGTGGCGCAGCTGAAGGACTTCATCACCAAGCTCGTGG ACATCGAGGAGAAGGACGAGCTGGACCTGCAGCGGACGCTGAGTTTGCAGGCGCCACCTGTGAAGGAGGGGCCACTCTTCATCCACAGGA CCAAGGGCAAGGGCCCCCTCATGTCCTCCTCCTTCAAGAAGCTCTACTTCTCCCTCACTACCGAGGCCCTCAGCTTCGCGAAGACGCCCA GCTCCAAGGTTGGGAAAAATAGCAGCCTAGCTTTGTCACAATCCAGTCCTTCAAGTATATCCAGCCCAGGACACAGCCGACAGAAGAACA CAAACAGAACGGGCAGGATAAGGACTCTTCCATAACAAGACTATGAAGCCACTTCCACATCAATTCCAGGCCACCTAATCCCATCCGAGG >72400_72400_2_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000262940_ATXN7L1_chr7_105251050_ENST00000477775_length(amino acids)=648AA_BP=610 MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHAVAFYVMDEDALSRDDVIGKVCLT RDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRW NETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLRDETVLPSSYYQ PLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAG MQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPAVVRATFRQLFRRVR ERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLK DFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKVGKNSSLALSQSSPSSISSP -------------------------------------------------------------- >72400_72400_3_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000449970_ATXN7L1_chr7_105251050_ENST00000419735_length(transcript)=4796nt_BP=1897nt AGTCCAGCGCCCGCCGCCCGCCACCCCGGACCCCGGTGTCTGGCTTCCCCCGAGCCGGGACCCCGCGATGGCCAAGCGCAGCTCGCTGTA CATCCGCATCGTGGAGGGGAAGAACCTTCCCGCCAAGGACATCACTGGCAGCAGCGACCCCTACTGCATCGTGAAGGTGGACAATGAGCC CATCATCAGGACAGCCACAGTGTGGAAGACCCTGTGCCCCTTCTGGGGTGAGGAGTACCAAGTGCACCTGCCGCCCACCTTCCACGCTGT GGCTTTCTATGTCATGGATGAGGATGCCCTCAGCCGGGACGACGTTATCGGAAAGGTCTGCCTTACAAGGGACACCATAGCCTCTCACCC TAAGGGTTTCAGCGGGTGGGCCCACCTGACGGAGGTCGACCCCGATGAGGAGGTGCAGGGCGAGATCCACCTGCGGCTGGAAGTGTGGCC AGGGGCCCGGGCCTGCCGGCTACGCTGCTCTGTGCTGGAGGCCAGGGATCTGGCCCCAAAGGACCGCAATGGCACATCTGACCCCTTCGT CCGAGTGCGCTACAAGGGCCGGACACGGGAGACCTCGATCGTGAAGAAGTCATGCTACCCACGCTGGAATGAGACGTTTGAATTTGAGCT GCAGGAGGGGGCCATGGAGGCGCTGTGCGTGGAGGCCTGGGACTGGGACCTTGTCAGCCGAAACGACTTCCTGGGCAAAGTGGTGATTGA TGTCCAGAGACTGCGGGTGGTGCAGCAGGAGGAGGGCTGGTTCCGGCTGCAGCCCGACCAGTCCAAGAGCCGGCGGCATGACGAGGGCAA CCTGGGCTCCTTGCAGCTGGAGGTGCGGCTGCGGGACGAGACGGTGCTGCCCTCCAGCTACTACCAGCCACTGGTGCACCTGCTGTGCCA CGAGGTCAAGCTGGGCATGCAGGGCCCAGGGCAGCTGATCCCACTCATCGAGGAGACAACCAGCACCGAGTGTCGCCAGGACGTGGCCAC GAACCTGCTCAAGCTCTTCCTGGGGCAGGGGCTGGCCAAGGACTTCCTGGACCTGCTCTTCCAGCTGGAGCTGAGTCGCACCAGTGAGAC CAACACCCTGTTCCGGAGCAACTCTCTGGCCTCAAAGTCCATGGAGTCTTTTCTGAAGGTGGCCGGGATGCAGTACCTGCACGGCGTCCT GGGCCCCATCATCAACAAGGTGTTTGAGGAGAAGAAGTACGTGGAGCTGGACCCCAGCAAAGTGGAAGTTAAGGATGTAGGGTGCTCCGG GCTGCACCGCCCGCAGACCGAGGCCGAGGTGCTGGAGCAGAGCGCGCAGACGCTGCGCGCCCACCTGGGGGCCCTGCTGAGCGCGCTCAG CCGCTCGGTTCGCGCGTGCCCCGCCGTGGTGCGCGCCACCTTCCGCCAGCTCTTCCGGCGCGTGCGCGAGCGCTTCCCCGGCGCCCAGCA CGAGAATGTACCGTTCATCGCCGTCACCAGCTTCCTGTGCCTGCGCTTCTTCTCTCCCGCCATCATGTCGCCCAAGCTCTTCCACCTGCG GGAGCGCCACGCGGACGCCCGCACCAGCCGCACCCTGCTCCTGTTGGCCAAGGCAGTCCAGAACGTGGGCAACATGGACACGCCGGCTTC CAGGGCCAAGGAGGCTTGGATGGAGCCGCTGCAGCCCACCGTGCGCCAGGGCGTGGCGCAGCTGAAGGACTTCATCACCAAGCTCGTGGA CATCGAGGAGAAGGACGAGCTGGACCTGCAGCGGACGCTGAGTTTGCAGGCGCCACCTGTGAAGGAGGGGCCACTCTTCATCCACAGGAC CAAGGGCAAGGGCCCCCTCATGTCCTCCTCCTTCAAGAAGCTCTACTTCTCCCTCACTACCGAGGCCCTCAGCTTCGCGAAGACGCCCAG CTCCAAGGTTGGGAAAAATAGCAGCCTAGCTTTGTCACAATCCAGTCCTTCAAGTATATCCAGCCCAGGACACAGCCGACAGAACACAAA CAGAACGGGCAGGATAAGGACTCTTCCATAACAAGACTATGAAGCCACTTCCACATCAATTCCAGGCCACCTAATCCCATCCGAGGAGGC CATGGGGAGGAGGAGGGAGGGGAGTGGGCTGGGGGGAGAGTCTGTTTTCTGTGCACTCCCTGTGACTCTGGCCTTTCTTCTTCTTTTTTT AATTGACCAATTTTTAGTTAAAAAGGCAAAAGAAGGTGAATTTGAGATTTACAGAAAACAGTTCCAGTGTTTGGTTTCCGCTGTCTTTCC TTTCATTTGCCATGTTTTTACATTCTTCCAAATTTGGGGTCACTCCCCTAGCTCCTGATGCTGCTACTGTACCATCCTTTTGCTCCAGCC ATGAGAGCAGACATTGCAGAATGTTGGTTCCAGGTTGGCATGCTCTGAAGCTCTTGAACTGTAGCACAGGCAGAGCCCTTTTTCTTCCTG TCATCTCCACCCGATTCCTTCCATCCCTACGTCTACCACTCTCTGGGTCCTCACTGGTCTTCAAAGGACCTGGCTCTCATAGGATCCCCT CAGGATTGTGTGCAGGGAGAGGGGGCTTTGCTGGGGAGGAGCTGGGAGTGGAGAGTTGGAGGGTGGGTGGGGTTCCCTCATCCAGTTTCC ACAGCCCACCATGGCTGGAGCCAAATGCTAGAAGCGAGATTGAGAACAGTGGCCGTTTAGTGATGTGGTTTACCTAATACCACTGTCCAG CTGTGCAGCTCAGAAAGGATAAACCAGTCAGGGACAGGGGCCAGAACAGGTTTGGGAAGGTGGCAGCAAGCAGAGCATGGTGGGTAGGAG ATGATCCCTAAAAAAACTGGAGACTGTGGTGGTCTGAGCTGGTCAGGAATCTGCAGAATCCCTTCCAGGAATCAGTGTGCCAGTGCCCAC AGCAGGGTGAGCTAGGAGGGAGAAATCCCAGGAAAAAGGTCGTGAGAACCCAGAAAGCCACTCCATGAGGAGGCACGGTGACCACAGCTG CTAAAGGTTCTTAGGCTGCCTTCCTGGGCTAGGAAGAGCCCCCCAGGGAGAGCTTCCACAAAAGGGTATGTGTCAAACCTTTTGTCAGAA TAAATAATAGCATTTCCCACCCACCCCCATGCCCTGGGCCACAGGGACTTGGTGGGATCAGCACACCCATGGATCAGCTTTTGCTGTCTT AGAGACAGCCATCCCCATGAAGGAATGGTAAGGACAGCCACTGCTCAGTGAAGAACAGCCATTTGGAAGAGCCACGCTGGAGCCCTGCAG CCATAGAACTATTCACACTGGAGTTTTAAAAGAAACAGCAATACCATAAGCTCTAGTAGGGAATCATAATCAGGAAAGGAATTCACAACA TAAAATAGGTGTTCTGTGCTATTAATCATGTAACTTTGTATATGATGTATAGCAAAGATACTGGGAGGTTTTGTTTCATCCTTAAATCAG AAATGAATGCTAGTTTCATAGCTGGGCAGAACCCTCATCCCCACCCCAAAGTTTTCCTTTTCTTTCCCGTTCCCCCAACCCAAAGATCAG ACTACTGTTAAGTTTCACCACACAATTGGAATTGCAAAGACGGGAGGCAAATGGAGTGATTTTCATCAATGGAATTGCACTGACAGTGAG TGTTTCTTATAGGATTACTAAATTTTTTAATATAAAATGATTTGTTTAAAAATCAGGAGTTGATATTAAGTACCAGGACATTAGTTCGGA TGATTTCATTTTTATTTCTACAGTGTTAAAAGTGCACTTATATGCTGGTTTATTTACGTCTTGGGAAAAGAGACTGCAAATTGAAGGGAT GATTGTTACTTTTTCTTTTTTTAAAAAAAAAAGGTTAAGGAGATTTTAAGACTTATAAATGTTTAAGAAATTATAAACAAGGTTAGACCC TTTGAAAAAAAGTTTAGAAGATATTCTTAAAGTAAATTTTTATAGTGTTAATTTTGTAATAATTTATGTTTTACTATATTACAGAGCTAA CTGACCAGAATAGTTTCAGAAACAATATGAAACTTAGGAAAGTTTAAGCAATGTTTATATTTTTAAAATGTTCTTTGAATTATGTTTTTA TTGTACATTTCTTCAGACTGAAAAGTATGTACATATCTTTGTTATTTTTGCACAATTTTGTCTTGTTCGGTTTCAGAGGTCTGTTGTTTT TTATAATTTATTTTGAGTTGTAAAACTTGCAGGAGTAAAAACAAAAAACAAAATCTCCACAACAAAATAACCCTCTGATTTATAAACTCT TATAGTCAAAGAGGGAAAACAAAGGTTGAGAGATTAAGTGGCTGCTTCTGAGAAATAATGTCTCAAGGACTAAAGGAGCAATTCAATAGG TTTAGACATTGTAGCTCTCTACATCTTGAATTGGAAGCTGGAATAAAGAGCCCCCACCCCCCCCCCCACCCTCATCGAATGCTGCTTACT TTGTCAAAAGACTGGCTATGACCAAGGTGAGGATATTTCTGGAAAACTGGGCAAAAAGGGAAAGCCCACAGTATTCTTCCTTGGCAGTCA ACCACAGGTTTACTTTACAATGATGTATTAAAAACTTGCAGCTTGAAAAATGGAATGCAAATAAAAGGTTCTCTTTGGGTTTGTCTTAAT GGAGTTAAACTGGAGCAGCCTATAAAACATTTTTAGGGTGATGTCCTCTGGGTCCTTCTGTTCTGCACACCCACTCAGTCTTCTCTCCCA GCCCCTTGACTGCACACACCCCTCTTTGCCTGAAGATCTCCTGACTTGTCGCCAGCCATAGAGGCTCGAAAGCTCTGGTTGTGAAGCATA >72400_72400_3_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000449970_ATXN7L1_chr7_105251050_ENST00000419735_length(amino acids)=647AA_BP=610 MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHAVAFYVMDEDALSRDDVIGKVCLT RDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRW NETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLRDETVLPSSYYQ PLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAG MQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPAVVRATFRQLFRRVR ERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLK DFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKVGKNSSLALSQSSPSSISSP -------------------------------------------------------------- >72400_72400_4_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000449970_ATXN7L1_chr7_105251050_ENST00000477775_length(transcript)=2095nt_BP=1897nt AGTCCAGCGCCCGCCGCCCGCCACCCCGGACCCCGGTGTCTGGCTTCCCCCGAGCCGGGACCCCGCGATGGCCAAGCGCAGCTCGCTGTA CATCCGCATCGTGGAGGGGAAGAACCTTCCCGCCAAGGACATCACTGGCAGCAGCGACCCCTACTGCATCGTGAAGGTGGACAATGAGCC CATCATCAGGACAGCCACAGTGTGGAAGACCCTGTGCCCCTTCTGGGGTGAGGAGTACCAAGTGCACCTGCCGCCCACCTTCCACGCTGT GGCTTTCTATGTCATGGATGAGGATGCCCTCAGCCGGGACGACGTTATCGGAAAGGTCTGCCTTACAAGGGACACCATAGCCTCTCACCC TAAGGGTTTCAGCGGGTGGGCCCACCTGACGGAGGTCGACCCCGATGAGGAGGTGCAGGGCGAGATCCACCTGCGGCTGGAAGTGTGGCC AGGGGCCCGGGCCTGCCGGCTACGCTGCTCTGTGCTGGAGGCCAGGGATCTGGCCCCAAAGGACCGCAATGGCACATCTGACCCCTTCGT CCGAGTGCGCTACAAGGGCCGGACACGGGAGACCTCGATCGTGAAGAAGTCATGCTACCCACGCTGGAATGAGACGTTTGAATTTGAGCT GCAGGAGGGGGCCATGGAGGCGCTGTGCGTGGAGGCCTGGGACTGGGACCTTGTCAGCCGAAACGACTTCCTGGGCAAAGTGGTGATTGA TGTCCAGAGACTGCGGGTGGTGCAGCAGGAGGAGGGCTGGTTCCGGCTGCAGCCCGACCAGTCCAAGAGCCGGCGGCATGACGAGGGCAA CCTGGGCTCCTTGCAGCTGGAGGTGCGGCTGCGGGACGAGACGGTGCTGCCCTCCAGCTACTACCAGCCACTGGTGCACCTGCTGTGCCA CGAGGTCAAGCTGGGCATGCAGGGCCCAGGGCAGCTGATCCCACTCATCGAGGAGACAACCAGCACCGAGTGTCGCCAGGACGTGGCCAC GAACCTGCTCAAGCTCTTCCTGGGGCAGGGGCTGGCCAAGGACTTCCTGGACCTGCTCTTCCAGCTGGAGCTGAGTCGCACCAGTGAGAC CAACACCCTGTTCCGGAGCAACTCTCTGGCCTCAAAGTCCATGGAGTCTTTTCTGAAGGTGGCCGGGATGCAGTACCTGCACGGCGTCCT GGGCCCCATCATCAACAAGGTGTTTGAGGAGAAGAAGTACGTGGAGCTGGACCCCAGCAAAGTGGAAGTTAAGGATGTAGGGTGCTCCGG GCTGCACCGCCCGCAGACCGAGGCCGAGGTGCTGGAGCAGAGCGCGCAGACGCTGCGCGCCCACCTGGGGGCCCTGCTGAGCGCGCTCAG CCGCTCGGTTCGCGCGTGCCCCGCCGTGGTGCGCGCCACCTTCCGCCAGCTCTTCCGGCGCGTGCGCGAGCGCTTCCCCGGCGCCCAGCA CGAGAATGTACCGTTCATCGCCGTCACCAGCTTCCTGTGCCTGCGCTTCTTCTCTCCCGCCATCATGTCGCCCAAGCTCTTCCACCTGCG GGAGCGCCACGCGGACGCCCGCACCAGCCGCACCCTGCTCCTGTTGGCCAAGGCAGTCCAGAACGTGGGCAACATGGACACGCCGGCTTC CAGGGCCAAGGAGGCTTGGATGGAGCCGCTGCAGCCCACCGTGCGCCAGGGCGTGGCGCAGCTGAAGGACTTCATCACCAAGCTCGTGGA CATCGAGGAGAAGGACGAGCTGGACCTGCAGCGGACGCTGAGTTTGCAGGCGCCACCTGTGAAGGAGGGGCCACTCTTCATCCACAGGAC CAAGGGCAAGGGCCCCCTCATGTCCTCCTCCTTCAAGAAGCTCTACTTCTCCCTCACTACCGAGGCCCTCAGCTTCGCGAAGACGCCCAG CTCCAAGGTTGGGAAAAATAGCAGCCTAGCTTTGTCACAATCCAGTCCTTCAAGTATATCCAGCCCAGGACACAGCCGACAGAAGAACAC AAACAGAACGGGCAGGATAAGGACTCTTCCATAACAAGACTATGAAGCCACTTCCACATCAATTCCAGGCCACCTAATCCCATCCGAGGA >72400_72400_4_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000449970_ATXN7L1_chr7_105251050_ENST00000477775_length(amino acids)=648AA_BP=610 MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHAVAFYVMDEDALSRDDVIGKVCLT RDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRW NETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLRDETVLPSSYYQ PLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAG MQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPAVVRATFRQLFRRVR ERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLK DFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKVGKNSSLALSQSSPSSISSP -------------------------------------------------------------- >72400_72400_5_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000462172_ATXN7L1_chr7_105251050_ENST00000419735_length(transcript)=4871nt_BP=1972nt GGACCCCGGTGTCTGGCTTCCCCCGAGCCGGGACCCCGCGATGGCCAAGCGCAGCTCGCTGTACATCCGCATCGTGGAGGGGAAGAACCT TCCCGCCAAGGACATGTGAGCGCGGCCGGGGGTGGGAGCCCCAACTTTCCGGGGAGGGGCACTGCCCCCCAGGACGCCTGACCTTTCCGG GGTCCACCCACAAGAGCAGCGGAGAGGCACTGGCAGCAGCGACCCCTACTGCATCGTGAAGGTGGACAATGAGCCCATCATCAGGACAGC CACAGTGTGGAAGACCCTGTGCCCCTTCTGGGGTGAGGAGTACCAAGTGCACCTGCCGCCCACCTTCCACGCTGTGGCTTTCTATGTCAT GGATGAGGATGCCCTCAGCCGGGACGACGTTATCGGAAAGGTCTGCCTTACAAGGGACACCATAGCCTCTCACCCTAAGGGTTTCAGCGG GTGGGCCCACCTGACGGAGGTCGACCCCGATGAGGAGGTGCAGGGCGAGATCCACCTGCGGCTGGAAGTGTGGCCAGGGGCCCGGGCCTG CCGGCTACGCTGCTCTGTGCTGGAGGCCAGGGATCTGGCCCCAAAGGACCGCAATGGCACATCTGACCCCTTCGTCCGAGTGCGCTACAA GGGCCGGACACGGGAGACCTCGATCGTGAAGAAGTCATGCTACCCACGCTGGAATGAGACGTTTGAATTTGAGCTGCAGGAGGGGGCCAT GGAGGCGCTGTGCGTGGAGGCCTGGGACTGGGACCTTGTCAGCCGAAACGACTTCCTGGGCAAAGTGGTGATTGATGTCCAGAGACTGCG GGTGGTGCAGCAGGAGGAGGGCTGGTTCCGGCTGCAGCCCGACCAGTCCAAGAGCCGGCGGCATGACGAGGGCAACCTGGGCTCCTTGCA GCTGGAGGTGCGGCTGCGGGACGAGACGGTGCTGCCCTCCAGCTACTACCAGCCACTGGTGCACCTGCTGTGCCACGAGGTCAAGCTGGG CATGCAGGGCCCAGGGCAGCTGATCCCACTCATCGAGGAGACAACCAGCACCGAGTGTCGCCAGGACGTGGCCACGAACCTGCTCAAGCT CTTCCTGGGGCAGGGGCTGGCCAAGGACTTCCTGGACCTGCTCTTCCAGCTGGAGCTGAGTCGCACCAGTGAGACCAACACCCTGTTCCG GAGCAACTCTCTGGCCTCAAAGTCCATGGAGTCTTTTCTGAAGGTGGCCGGGATGCAGTACCTGCACGGCGTCCTGGGCCCCATCATCAA CAAGGTGTTTGAGGAGAAGAAGTACGTGGAGCTGGACCCCAGCAAAGTGGAAGTTAAGGATGTAGGGTGCTCCGGGCTGCACCGCCCGCA GACCGAGGCCGAGGTGCTGGAGCAGAGCGCGCAGACGCTGCGCGCCCACCTGGGGGCCCTGCTGAGCGCGCTCAGCCGCTCGGTTCGCGC GTGCCCCGCCGTGGTGCGCGCCACCTTCCGCCAGCTCTTCCGGCGCGTGCGCGAGCGCTTCCCCGGCGCCCAGCACGAGAATGTACCGTT CATCGCCGTCACCAGCTTCCTGTGCCTGCGCTTCTTCTCTCCCGCCATCATGTCGCCCAAGCTCTTCCACCTGCGGGAGCGCCACGCGGA CGCCCGCACCAGCCGCACCCTGCTCCTGTTGGCCAAGGCAGTCCAGAACGTGGGCAACATGGACACGCCGGCTTCCAGGGCCAAGGAGGC TTGGATGGAGCCGCTGCAGCCCACCGTGCGCCAGGGCGTGGCGCAGCTGAAGGACTTCATCACCAAGCTCGTGGACATCGAGGAGAAGGA CGAGCTGGACCTGCAGCGGACGCTGAGTTTGCAGGCGCCACCTGTGAAGGAGGGGCCACTCTTCATCCACAGGACCAAGGGCAAGGGCCC CCTCATGTCCTCCTCCTTCAAGAAGCTCTACTTCTCCCTCACTACCGAGGCCCTCAGCTTCGCGAAGACGCCCAGCTCCAAGGTTGGGAA AAATAGCAGCCTAGCTTTGTCACAATCCAGTCCTTCAAGTATATCCAGCCCAGGACACAGCCGACAGAACACAAACAGAACGGGCAGGAT AAGGACTCTTCCATAACAAGACTATGAAGCCACTTCCACATCAATTCCAGGCCACCTAATCCCATCCGAGGAGGCCATGGGGAGGAGGAG GGAGGGGAGTGGGCTGGGGGGAGAGTCTGTTTTCTGTGCACTCCCTGTGACTCTGGCCTTTCTTCTTCTTTTTTTAATTGACCAATTTTT AGTTAAAAAGGCAAAAGAAGGTGAATTTGAGATTTACAGAAAACAGTTCCAGTGTTTGGTTTCCGCTGTCTTTCCTTTCATTTGCCATGT TTTTACATTCTTCCAAATTTGGGGTCACTCCCCTAGCTCCTGATGCTGCTACTGTACCATCCTTTTGCTCCAGCCATGAGAGCAGACATT GCAGAATGTTGGTTCCAGGTTGGCATGCTCTGAAGCTCTTGAACTGTAGCACAGGCAGAGCCCTTTTTCTTCCTGTCATCTCCACCCGAT TCCTTCCATCCCTACGTCTACCACTCTCTGGGTCCTCACTGGTCTTCAAAGGACCTGGCTCTCATAGGATCCCCTCAGGATTGTGTGCAG GGAGAGGGGGCTTTGCTGGGGAGGAGCTGGGAGTGGAGAGTTGGAGGGTGGGTGGGGTTCCCTCATCCAGTTTCCACAGCCCACCATGGC TGGAGCCAAATGCTAGAAGCGAGATTGAGAACAGTGGCCGTTTAGTGATGTGGTTTACCTAATACCACTGTCCAGCTGTGCAGCTCAGAA AGGATAAACCAGTCAGGGACAGGGGCCAGAACAGGTTTGGGAAGGTGGCAGCAAGCAGAGCATGGTGGGTAGGAGATGATCCCTAAAAAA ACTGGAGACTGTGGTGGTCTGAGCTGGTCAGGAATCTGCAGAATCCCTTCCAGGAATCAGTGTGCCAGTGCCCACAGCAGGGTGAGCTAG GAGGGAGAAATCCCAGGAAAAAGGTCGTGAGAACCCAGAAAGCCACTCCATGAGGAGGCACGGTGACCACAGCTGCTAAAGGTTCTTAGG CTGCCTTCCTGGGCTAGGAAGAGCCCCCCAGGGAGAGCTTCCACAAAAGGGTATGTGTCAAACCTTTTGTCAGAATAAATAATAGCATTT CCCACCCACCCCCATGCCCTGGGCCACAGGGACTTGGTGGGATCAGCACACCCATGGATCAGCTTTTGCTGTCTTAGAGACAGCCATCCC CATGAAGGAATGGTAAGGACAGCCACTGCTCAGTGAAGAACAGCCATTTGGAAGAGCCACGCTGGAGCCCTGCAGCCATAGAACTATTCA CACTGGAGTTTTAAAAGAAACAGCAATACCATAAGCTCTAGTAGGGAATCATAATCAGGAAAGGAATTCACAACATAAAATAGGTGTTCT GTGCTATTAATCATGTAACTTTGTATATGATGTATAGCAAAGATACTGGGAGGTTTTGTTTCATCCTTAAATCAGAAATGAATGCTAGTT TCATAGCTGGGCAGAACCCTCATCCCCACCCCAAAGTTTTCCTTTTCTTTCCCGTTCCCCCAACCCAAAGATCAGACTACTGTTAAGTTT CACCACACAATTGGAATTGCAAAGACGGGAGGCAAATGGAGTGATTTTCATCAATGGAATTGCACTGACAGTGAGTGTTTCTTATAGGAT TACTAAATTTTTTAATATAAAATGATTTGTTTAAAAATCAGGAGTTGATATTAAGTACCAGGACATTAGTTCGGATGATTTCATTTTTAT TTCTACAGTGTTAAAAGTGCACTTATATGCTGGTTTATTTACGTCTTGGGAAAAGAGACTGCAAATTGAAGGGATGATTGTTACTTTTTC TTTTTTTAAAAAAAAAAGGTTAAGGAGATTTTAAGACTTATAAATGTTTAAGAAATTATAAACAAGGTTAGACCCTTTGAAAAAAAGTTT AGAAGATATTCTTAAAGTAAATTTTTATAGTGTTAATTTTGTAATAATTTATGTTTTACTATATTACAGAGCTAACTGACCAGAATAGTT TCAGAAACAATATGAAACTTAGGAAAGTTTAAGCAATGTTTATATTTTTAAAATGTTCTTTGAATTATGTTTTTATTGTACATTTCTTCA GACTGAAAAGTATGTACATATCTTTGTTATTTTTGCACAATTTTGTCTTGTTCGGTTTCAGAGGTCTGTTGTTTTTTATAATTTATTTTG AGTTGTAAAACTTGCAGGAGTAAAAACAAAAAACAAAATCTCCACAACAAAATAACCCTCTGATTTATAAACTCTTATAGTCAAAGAGGG AAAACAAAGGTTGAGAGATTAAGTGGCTGCTTCTGAGAAATAATGTCTCAAGGACTAAAGGAGCAATTCAATAGGTTTAGACATTGTAGC TCTCTACATCTTGAATTGGAAGCTGGAATAAAGAGCCCCCACCCCCCCCCCCACCCTCATCGAATGCTGCTTACTTTGTCAAAAGACTGG CTATGACCAAGGTGAGGATATTTCTGGAAAACTGGGCAAAAAGGGAAAGCCCACAGTATTCTTCCTTGGCAGTCAACCACAGGTTTACTT TACAATGATGTATTAAAAACTTGCAGCTTGAAAAATGGAATGCAAATAAAAGGTTCTCTTTGGGTTTGTCTTAATGGAGTTAAACTGGAG CAGCCTATAAAACATTTTTAGGGTGATGTCCTCTGGGTCCTTCTGTTCTGCACACCCACTCAGTCTTCTCTCCCAGCCCCTTGACTGCAC ACACCCCTCTTTGCCTGAAGATCTCCTGACTTGTCGCCAGCCATAGAGGCTCGAAAGCTCTGGTTGTGAAGCATAACGCAATGCATAGAC >72400_72400_5_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000462172_ATXN7L1_chr7_105251050_ENST00000419735_length(amino acids)=644AA_BP=607 MPPRTPDLSGVHPQEQRRGTGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHAVAFYVMDEDALSRDDVIGKVCLTRDT IASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET FEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLRDETVLPSSYYQPLV HLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAGMQY LHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPAVVRATFRQLFRRVRERF PGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDFI TKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKVGKNSSLALSQSSPSSISSPGHS -------------------------------------------------------------- >72400_72400_6_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000462172_ATXN7L1_chr7_105251050_ENST00000477775_length(transcript)=2170nt_BP=1972nt GGACCCCGGTGTCTGGCTTCCCCCGAGCCGGGACCCCGCGATGGCCAAGCGCAGCTCGCTGTACATCCGCATCGTGGAGGGGAAGAACCT TCCCGCCAAGGACATGTGAGCGCGGCCGGGGGTGGGAGCCCCAACTTTCCGGGGAGGGGCACTGCCCCCCAGGACGCCTGACCTTTCCGG GGTCCACCCACAAGAGCAGCGGAGAGGCACTGGCAGCAGCGACCCCTACTGCATCGTGAAGGTGGACAATGAGCCCATCATCAGGACAGC CACAGTGTGGAAGACCCTGTGCCCCTTCTGGGGTGAGGAGTACCAAGTGCACCTGCCGCCCACCTTCCACGCTGTGGCTTTCTATGTCAT GGATGAGGATGCCCTCAGCCGGGACGACGTTATCGGAAAGGTCTGCCTTACAAGGGACACCATAGCCTCTCACCCTAAGGGTTTCAGCGG GTGGGCCCACCTGACGGAGGTCGACCCCGATGAGGAGGTGCAGGGCGAGATCCACCTGCGGCTGGAAGTGTGGCCAGGGGCCCGGGCCTG CCGGCTACGCTGCTCTGTGCTGGAGGCCAGGGATCTGGCCCCAAAGGACCGCAATGGCACATCTGACCCCTTCGTCCGAGTGCGCTACAA GGGCCGGACACGGGAGACCTCGATCGTGAAGAAGTCATGCTACCCACGCTGGAATGAGACGTTTGAATTTGAGCTGCAGGAGGGGGCCAT GGAGGCGCTGTGCGTGGAGGCCTGGGACTGGGACCTTGTCAGCCGAAACGACTTCCTGGGCAAAGTGGTGATTGATGTCCAGAGACTGCG GGTGGTGCAGCAGGAGGAGGGCTGGTTCCGGCTGCAGCCCGACCAGTCCAAGAGCCGGCGGCATGACGAGGGCAACCTGGGCTCCTTGCA GCTGGAGGTGCGGCTGCGGGACGAGACGGTGCTGCCCTCCAGCTACTACCAGCCACTGGTGCACCTGCTGTGCCACGAGGTCAAGCTGGG CATGCAGGGCCCAGGGCAGCTGATCCCACTCATCGAGGAGACAACCAGCACCGAGTGTCGCCAGGACGTGGCCACGAACCTGCTCAAGCT CTTCCTGGGGCAGGGGCTGGCCAAGGACTTCCTGGACCTGCTCTTCCAGCTGGAGCTGAGTCGCACCAGTGAGACCAACACCCTGTTCCG GAGCAACTCTCTGGCCTCAAAGTCCATGGAGTCTTTTCTGAAGGTGGCCGGGATGCAGTACCTGCACGGCGTCCTGGGCCCCATCATCAA CAAGGTGTTTGAGGAGAAGAAGTACGTGGAGCTGGACCCCAGCAAAGTGGAAGTTAAGGATGTAGGGTGCTCCGGGCTGCACCGCCCGCA GACCGAGGCCGAGGTGCTGGAGCAGAGCGCGCAGACGCTGCGCGCCCACCTGGGGGCCCTGCTGAGCGCGCTCAGCCGCTCGGTTCGCGC GTGCCCCGCCGTGGTGCGCGCCACCTTCCGCCAGCTCTTCCGGCGCGTGCGCGAGCGCTTCCCCGGCGCCCAGCACGAGAATGTACCGTT CATCGCCGTCACCAGCTTCCTGTGCCTGCGCTTCTTCTCTCCCGCCATCATGTCGCCCAAGCTCTTCCACCTGCGGGAGCGCCACGCGGA CGCCCGCACCAGCCGCACCCTGCTCCTGTTGGCCAAGGCAGTCCAGAACGTGGGCAACATGGACACGCCGGCTTCCAGGGCCAAGGAGGC TTGGATGGAGCCGCTGCAGCCCACCGTGCGCCAGGGCGTGGCGCAGCTGAAGGACTTCATCACCAAGCTCGTGGACATCGAGGAGAAGGA CGAGCTGGACCTGCAGCGGACGCTGAGTTTGCAGGCGCCACCTGTGAAGGAGGGGCCACTCTTCATCCACAGGACCAAGGGCAAGGGCCC CCTCATGTCCTCCTCCTTCAAGAAGCTCTACTTCTCCCTCACTACCGAGGCCCTCAGCTTCGCGAAGACGCCCAGCTCCAAGGTTGGGAA AAATAGCAGCCTAGCTTTGTCACAATCCAGTCCTTCAAGTATATCCAGCCCAGGACACAGCCGACAGAAGAACACAAACAGAACGGGCAG GATAAGGACTCTTCCATAACAAGACTATGAAGCCACTTCCACATCAATTCCAGGCCACCTAATCCCATCCGAGGAGGCCATGGGGAGGAG >72400_72400_6_RASA4-ATXN7L1_RASA4_chr7_102232732_ENST00000462172_ATXN7L1_chr7_105251050_ENST00000477775_length(amino acids)=645AA_BP=607 MPPRTPDLSGVHPQEQRRGTGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHAVAFYVMDEDALSRDDVIGKVCLTRDT IASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET FEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLRDETVLPSSYYQPLV HLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAGMQY LHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPAVVRATFRQLFRRVRERF PGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDFI TKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKVGKNSSLALSQSSPSSISSPGHS -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for RASA4-ATXN7L1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for RASA4-ATXN7L1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for RASA4-ATXN7L1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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