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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:RBFA-SPG11 (FusionGDB2 ID:72634) |
Fusion Gene Summary for RBFA-SPG11 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RBFA-SPG11 | Fusion gene ID: 72634 | Hgene | Tgene | Gene symbol | RBFA | SPG11 | Gene ID | 79863 | 80208 |
| Gene name | ribosome binding factor A | SPG11 vesicle trafficking associated, spatacsin | |
| Synonyms | C18orf22|HsT169 | ALS5|CMT2X|KIAA1840 | |
| Cytomap | 18q23 | 15q21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | putative ribosome-binding factor A, mitochondrialribosome binding factor A (putative) | spatacsinSPG11, spatacsin vesicle trafficking associatedamyotrophic lateral sclerosis 5colorectal carcinoma-associated proteinspastic paraplegia 11 (autosomal recessive)spastic paraplegia 11 protein | |
| Modification date | 20200313 | 20200329 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000586847, ENST00000262197, ENST00000306735, | ENST00000261866, ENST00000427534, ENST00000535302, ENST00000558319, ENST00000558253, ENST00000559193, | |
| Fusion gene scores | * DoF score | 6 X 7 X 6=252 | 10 X 11 X 5=550 |
| # samples | 8 | 11 | |
| ** MAII score | log2(8/252*10)=-1.65535182861255 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(11/550*10)=-2.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RBFA [Title/Abstract] AND SPG11 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | RBFA(77794653)-SPG11(44952814), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across RBFA (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across SPG11 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | OV | TCGA-13-0797 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
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Fusion Gene ORF analysis for RBFA-SPG11 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000586847 | ENST00000261866 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| 3UTR-3CDS | ENST00000586847 | ENST00000427534 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| 3UTR-3CDS | ENST00000586847 | ENST00000535302 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| 3UTR-3CDS | ENST00000586847 | ENST00000558319 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| 3UTR-intron | ENST00000586847 | ENST00000558253 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| 3UTR-intron | ENST00000586847 | ENST00000559193 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| 5CDS-intron | ENST00000262197 | ENST00000558253 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| 5CDS-intron | ENST00000262197 | ENST00000559193 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| 5CDS-intron | ENST00000306735 | ENST00000558253 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| 5CDS-intron | ENST00000306735 | ENST00000559193 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| In-frame | ENST00000262197 | ENST00000261866 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| In-frame | ENST00000262197 | ENST00000427534 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| In-frame | ENST00000262197 | ENST00000535302 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| In-frame | ENST00000262197 | ENST00000558319 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| In-frame | ENST00000306735 | ENST00000261866 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| In-frame | ENST00000306735 | ENST00000427534 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| In-frame | ENST00000306735 | ENST00000535302 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| In-frame | ENST00000306735 | ENST00000558319 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000306735 | RBFA | chr18 | 77794653 | + | ENST00000261866 | SPG11 | chr15 | 44952814 | - | 7796 | 296 | 9 | 7370 | 2453 |
| ENST00000306735 | RBFA | chr18 | 77794653 | + | ENST00000535302 | SPG11 | chr15 | 44952814 | - | 7299 | 296 | 9 | 7031 | 2340 |
| ENST00000306735 | RBFA | chr18 | 77794653 | + | ENST00000427534 | SPG11 | chr15 | 44952814 | - | 6974 | 296 | 9 | 6836 | 2275 |
| ENST00000306735 | RBFA | chr18 | 77794653 | + | ENST00000558319 | SPG11 | chr15 | 44952814 | - | 6434 | 296 | 9 | 6278 | 2089 |
| ENST00000262197 | RBFA | chr18 | 77794653 | + | ENST00000261866 | SPG11 | chr15 | 44952814 | - | 7688 | 188 | 30 | 7262 | 2410 |
| ENST00000262197 | RBFA | chr18 | 77794653 | + | ENST00000535302 | SPG11 | chr15 | 44952814 | - | 7191 | 188 | 30 | 6923 | 2297 |
| ENST00000262197 | RBFA | chr18 | 77794653 | + | ENST00000427534 | SPG11 | chr15 | 44952814 | - | 6866 | 188 | 30 | 6728 | 2232 |
| ENST00000262197 | RBFA | chr18 | 77794653 | + | ENST00000558319 | SPG11 | chr15 | 44952814 | - | 6326 | 188 | 30 | 6170 | 2046 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000306735 | ENST00000261866 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - | 0.000966666 | 0.99903333 |
| ENST00000306735 | ENST00000535302 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - | 0.001484874 | 0.99851507 |
| ENST00000306735 | ENST00000427534 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - | 0.000921989 | 0.99907804 |
| ENST00000306735 | ENST00000558319 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - | 0.000829738 | 0.9991703 |
| ENST00000262197 | ENST00000261866 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - | 0.00087104 | 0.999129 |
| ENST00000262197 | ENST00000535302 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - | 0.001360204 | 0.99863976 |
| ENST00000262197 | ENST00000427534 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - | 0.000836888 | 0.99916315 |
| ENST00000262197 | ENST00000558319 | RBFA | chr18 | 77794653 | + | SPG11 | chr15 | 44952814 | - | 0.000736531 | 0.99926347 |
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Fusion Genomic Features for RBFA-SPG11 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for RBFA-SPG11 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:77794653/chr15:44952814) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for RBFA-SPG11 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >72634_72634_1_RBFA-SPG11_RBFA_chr18_77794653_ENST00000262197_SPG11_chr15_44952814_ENST00000261866_length(transcript)=7688nt_BP=188nt CCTGCTCGCTCCGGGTCCCGGCGCCGCGCCATGTGGGCTGCGGCGGGCGGGCTGTGGCGCTCCCGCGCGGGTCTCCGGGCCCTGTTCCGT AGCCGCGATGCTGCGCTATTTCCAGGCTGCGAGCGGGGACTTCACTGCTCTGCTGTCTCCTGCAAGAACTGGCTCAAGAAATTTGCCTCG AAAACCAACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTG CTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGAC GATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATC CTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATT ATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTA GCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAA GTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCA GGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTAC AACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAA CTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGC TGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGG AAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTG GAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGAC AGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAAC AGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTA GAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCT GTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAAATGTGGAAGAGCTGATACCAGCATTGGATTTACTTTGCTCGGCA ATTAGAGAAAGTTATTCTGAACCCCAAAGCAAACACTTTTCAGAACAATTGCTTAATCTTACACTGTCTTTCCTTAACAACCAAATAAAG GAGCTTTTCATTCACACTGAAGAACTAGATGAACATCTGCAAAAAGGAGTGAACATTTTGACTAGCTACATTAATGAACTTCGAACCTTC ATGATAAAGTTTCCTTGGAAGCTAACAGATGCTATAGATGAATATGATGTACATGAAAATGTCCCCAAAGTAAAGGAGAGCAATATATGG AAGAAACTCAGCTTTGAGGAAGTTATTGCCAGCGCCATTTTAAACAACAAAATACCAGAGGCACAGACTTTCTTCAGGATTGATAGTCAT TCTGCTCAAAAACTTGAGGAGCTTATTGGCATAGGCCTAAATTTGGTCTTTGACAATTTAAAAAAGAACAATATAAAGGAAGCCTCTGAA CTTTTGAAGAATATGGGGTTTGATGTAAAAGGCCAATTGCTCAAGATCTGCTTCTATACAACTAATAAAAATATACGTGACTTTTTGGTT GAAATTTTAAAAGAAAAAAATTATTTTTCTGAAAAAGAGAAAAGAACTATAGACTTCGTGCATCAAGTTGAGAAGCTTTATTTGGGACAT TTCCAAGAAAATATGCAAATCCAGTCATTTCCCAGGTACTGGATAAAGGAACAAGATTTTTTCAAGCACAAGTCTGTTTTGGACTCATTC CTGAAATATGATTGTAAAGATGAATTTAACAAACAGGACCATAGAATTGTGTTAAATTGGGCTCTGTGGTGGGATCAACTAACACAAGAA TCCATCCTTCTCCCCAGGATAAGTCCAGAAGAATACAAATCATATTCCCCTGAAGCCCTCTGGAGATACCTCACAGCTCGCCATGATTGG TTAAACATTATCTTATGGATTGGAGAATTTCAAACCCAGCATAGTTATGCTTCACTTCAGCAGAACAAATGGCCCCTTCTGACTGTTGAT GTTATTAACCAGAATACTTCCTGTAACAACTACATGAGGAATGAAATTTTAGATAAGCTGGCCAGGAATGGGGTTTTTTTGGCATCTGAA CTGGAAGACTTTGAATGCTTCCTCCTAAGACTGAGCCGTATTGGAGGTGTAATACAGGATACCCTCCCTGTTCAAAACTACAAGACCAAA GAAGGTTGGGATTTCCATTCTCAATTCATTCTCTATTGTTTGGAGCACAGTCTGCAGCATCTTCTTTATGTCTACCTTGACTGTTACAAA CTTAGTCCTGAAAATTGTCCCTTTTTGGAAAAAAAAGAGTTACATGAAGCACACCCTTGGTTTGAATTTTTAGTTCAGTGTCGACAAGTT GCCAGTAACTTAACAGATCCCAAACTGATCTTCCAGGCTAGCCTTGCAAATGCTCAGATTTTGATTCCCACCAATCAGGCCAGTGTAAGC AGTATGCTATTGGAAGGACATACCCTCCTGGCCCTTGCTACTACAATGTATTCTCCTGGGGGTGTCAGTCAGGTTGTTCAGAATGAAGAA AATGAAAACTGTTTGAAGAAAGTGGATCCCCAGCTATTGAAGATGGCATTAACTCCTTACCCCAAGCTAAAAACTGCTCTCTTCCCACAG TGCACTCCTCCTAGTGTCCTGCCATCTGATATTACAATCTACCACCTTATTCAGTCATTATCACCCTTTGATCCTAGCAGATTGTTTGGC TGGCAGTCTGCTAACACACTAGCTATAGGAGATGCATGGAGTCATCTCCCACATTTCTCTAGCCCTGACCTGGTTAATAAATATGCTATA GTGGAACGTCTGAATTTTGCTTATTATTTACATAATGGGCGGCCATCATTTGCATTTGGTACTTTTCTGGTCCAGGAATTAATCAAGAGC AAGACTCCCAAGCAGCTGATCCAGCAAGTAGGCAATGAAGCCTATGTTATAGGGCTCTCCTCCTTCCACATACCTTCAATAGGAGCTGCA TGTGTTTGTTTCTTAGAATTGCTTGGCCTTGACAGCCTCAAGCTCAGAGTTGATATGAAAGTGGCCAATATAATTTTGAGCTACAAGTGC AGAAATGAAGATGCTCAGTACAGCTTTATCAGAGAGTCTGTAGCCGAAAAACTATCTAAACTAGCTGATGGTGAAAAGACAACCACAGAA GAATTGCTTGTTCTCTTAGAAGAAGGTACATGGAACAGCATTCAGCAACAGGAAATAAAGAGGTTATCCAGTGAATCTAGCAGCCAATGG GCATTAGTGGTGCAGTTCTGCAGGCTACACAATATGAAACTAAGCATATCTTACCTTAGAGAATGTGCCAAAGCAAATGATTGGCTGCAG TTCATTATTCACAGCCAACTCCACAACTACCACCCAGCAGAGGTGAAATCCCTTATCCAGTACTTCAGCCCAGTCATTCAAGACCACTTA AGGCTGGCTTTTGAGAACTTGCCCTCAGTGCCCACCTCCAAAATGGACAGCGATCAAGTCTGCAATAAGTGCCCCCAGGAACTTCAAGGA AGCAAACAAGAGATGACCGATTTATTTGAAATTCTGCTCCAATGCTCAGAGGAGCCAGACTCCTGGCACTGGCTTCTGGTTGAAGCAGTG AAACAACAGGCCCCTATCCTCAGTGTTCTGGCCTCATGTCTCCAGGGTGCCAGTGCCATTTCTTGTCTCTGTGTTTGGATCATCACTTCT GTGGAGGACAATGTTGCAACTGAAGCAATGGGACACATTCAGGACTCAACAGAGGACCATACCTGGAACCTTGAGGATCTTTCAGTCATC TGGAGAACATTATTAACAAGACAAAAGAGCAAAACTCTCATCAGAGGTTTCCAGCTTTTCTTTAAGGATTCCCCGTTACTACTGGTGATG GAGATGTATGAACTGTGTATGTTCTTCAGGAATTATAAAGAAGCTGAAGCTAAACTTCTGGAGTTTCAGAAGAGCCTTGAAACGCTTAAC ACAGCAGCCACAAAGGTCCACCCTGTCATCCCTGCCATGTGGCTGGAGGATCAGGTGTGTTTCCTTTTGAAGCTTATGCTACAGCAGTGT AAGACCCAGTATGAGCTGGGGAAGCTTTTACAGCTCTTTGTTGAAAGAGAGCATCTCTTCTCTGATGGTCCAGATGTGAAAAAGCTTTGC ATCCTTTGCCAGATTTTGAAGGATACATCCATAGCCATTAATCATACAATTATTACCAGCTACAGCATTGAGAATCTTCAGCATGAATGT AGATCTATTTTGGAAAGACTGCAGACAGATGGACAATTCGCTTTGGCCAGGAGGGTAGCAGAATTAGCTGAGTTACCTGTGGACAACTTG GTTATTAAAGAGATAACACAGGAAATGCAGACCCTAAAACACATTGAACAGTGGTCACTAAAACAAGCAAGAATTGACTTCTGGAAAAAA TGCCATGAGAATTTTAAGAAAAATTCAATTTCAAGCAAAGCAGCTTCTTCCTTTTTCTCAACCCAGGCCCATGTGGCATGTGAGCACCCA ACTGGATGGAGCAGCATGGAGGAGCGCCATCTGCTGCTCACCTTGGCAGGGCACTGGCTTGCCCAGGAGGACGTGGTGCCCTTGGATAAG CTGGAGGAGCTGGAGAAGCAGATCTGGCTGTGCCGCATCACCCAGCACACTCTTGGAAGAAATCAGGAGGAAACAGAGCCCAGATTTTCT CGACAGATCTCAACTAGTGGTGAACTTTCCTTTGATAGTTTAGCCAGTGAGTTTTCCTTCTCCAAGTTGGCTGCTCTGAACACATCAAAA TACTTAGAACTTAACAGCCTTCCATCCAAAGAGACATGCGAGAATAGATTGGATTGGAAAGAGCAGGAGTCACTAAACTTTTTGATTGGG CGCCTACTGGATGATGGCTGTGTGCATGAAGCAAGTAGAGTATGCCGGTATTTTCATTTTTATAATCCAGATGTCGCCTTGGTATTGCAC TGCAGAGCACTGGCCTCAGGGGAAGCTAGTATGGAGGATCTGCACCCAGAGATCCATGCTCTCCTACAAAGTGCTGAGCTGCTTGAGGAA GAAGCACCCGACATTCCCCTAAGGAGAGTCCACAGCACTTCAAGTCTGGATAGTCAGAAGTTTGTGACAGTGCCCTCCAGTAATGAAGTG GTAACTAACCTGGAAGTGCTGACAAGCAAATGCCTCCATGGGAAGAACTACTGTCGACAGGTCCTCTGTCTGTATGATCTTGCCAAGGAG TTGGGCTGTTCCTACACAGATGTTGCTGCTCAGGATGGTGAAGCCATGCTCCGGAAAATCTTGGCCTCTCAGCAGCCTGACCGATGCAAA CGAGCCCAGGCCTTCATCAGCACACAGGGCCTTAAGCCAGATACTGTGGCTGAACTCGTGGCAGAAGAGGTGACACGGGAGCTGCTTACT TCATCACAGGGAACAGGACATAAGCAGATGTTCAACCCAACAGAGGAAAGCCAGACATTTCTTCAGCTGACCACTCTGTGTCAAGACCGC ACATTGGTAGGCATGAAGTTGTTGGATAAGATTTCCTCCGTTCCCCATGGGGAACTGTCTTGCACCACAGAGCTCCTGATCCTGGCCCAT CATTGCTTCACCCTGACGTGCCACATGGAGGGCATCATCCGAGTCCTACAGGCCGCCCACATGCTCACAGATAACCACCTGGCCCCCAGT GAGGAGTATGGGCTGGTGGTACGGCTCCTCACTGGCATTGGAAGGTACAACGAGATGACATACATATTTGATTTGCTGCATAAAAAGCAC TACTTTGAAGTGCTAATGAGGAAGAAGTTGGATCCGAGTGGTACCCTGAAAACAGCCCTGCTGGACTACATCAAACGCTGCCGTCCTGGA GACAGTGAAAAGCACAATATGATTGCCCTGTGCTTCAGCATGTGCCGGGAGATTGGCGAGAACCACGAGGCAGCTGCCCGCATCCAACTG AAATTGATTGAGTCTCAGCCCTGGGAGGACAGCCTCAAGGATGGGCACCAGCTGAAACAACTGCTGCTGAAGGCCCTGACTCTGATGTTG GATGCAGCAGAGAGTTATGCCAAGGACTCCTGTGTGCGACAGGCCCAGCACTGTCAGCGGCTCACCAAGTTGATAACTCTGCAGATTCAC TTTCTGAACACTGGCCAGAACACAATGCTCATCAACTTGGGCCGCCACAAGCTGATGGACTGTATTCTGGCCCTACCTCGGTTCTACCAG GCTTCTATTGTGGCTGAGGCCTACGATTTTGTTCCAGATTGGGCTGAAATTTTATACCAGCAAGTGATTCTTAAAGGAGACTTTAATTAC TTGGAAGAATTTAAGCAGCAAAGGTTATTAAAGTCCAGTATATTTGAAGAGATTTCCAAAAAATATAAACAACATCAGCCTACTGACATG GTCATGGAAAACCTGAAGAAATTACTCACATATTGTGAAGATGTTTACCTGTATTACAAGTTGGCATACGAACACAAGTTTTATGAAATT GTAAATGTGCTTCTGAAGGACCCTCAGACAGGTTGCTGTCTAAAGGACATGCTAGCAGGTTAGATGATTTCATAGGTGTCTGTTTTCTTG TACTGTTAGCAGATTCTGACAGATGTGATGAGAAGAAGAATGCATTGGAGATCTTTGCTAAAGTTGAACAATCCCGGTACTGTACCATAT CAGTCCTTTGTGGGTAGTAGGTAGCAAGTAAGAAACTTTTCAGGAGGAAATTCCTATTTAAAATAGATTGATTTTAGATGATTGTTCATC CACACCATTTTATATAGATACTAGTATTAAGATCAAAAGCTTCCTCTTCCTCAGGACAGCTTCTACTTTAGATGATCCAATAATGATTAA AGAATACCTGTACCTGCAGATTCCAGTTTCAAAGAAATTTAATTATTATTTACACAGTTAAGGAACAGGTGATACATTTTCATTTGTTAG >72634_72634_1_RBFA-SPG11_RBFA_chr18_77794653_ENST00000262197_SPG11_chr15_44952814_ENST00000261866_length(amino acids)=2410AA_BP=53 MWAAAGGLWRSRAGLRALFRSRDAALFPGCERGLHCSAVSCKNWLKKFASKTNFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDG RCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGIL FVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILE DLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMH GQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFV LTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSS HLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNNQIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTD AIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRIDSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVK GQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLYLGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFN KQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNN YMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNYKTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLE KKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDP QLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSRLFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYL HNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSIGAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFI RESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESSSQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNY HPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQELQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVL ASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDLSVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFR NYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLMLQQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTS IAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPVDNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSI SSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVPLDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELS FDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNFLIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEAS MEDLHPEIHALLQSAELLEEEAPDIPLRRVHSTSSLDSQKFVTVPSSNEVVTNLEVLTSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAA QDGEAMLRKILASQQPDRCKRAQAFISTQGLKPDTVAELVAEEVTRELLTSSQGTGHKQMFNPTEESQTFLQLTTLCQDRTLVGMKLLDK ISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLQAAHMLTDNHLAPSEEYGLVVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKL DPSGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAARIQLKLIESQPWEDSLKDGHQLKQLLLKALTLMLDAAESYAKDS CVRQAQHCQRLTKLITLQIHFLNTGQNTMLINLGRHKLMDCILALPRFYQASIVAEAYDFVPDWAEILYQQVILKGDFNYLEEFKQQRLL -------------------------------------------------------------- >72634_72634_2_RBFA-SPG11_RBFA_chr18_77794653_ENST00000262197_SPG11_chr15_44952814_ENST00000427534_length(transcript)=6866nt_BP=188nt CCTGCTCGCTCCGGGTCCCGGCGCCGCGCCATGTGGGCTGCGGCGGGCGGGCTGTGGCGCTCCCGCGCGGGTCTCCGGGCCCTGTTCCGT AGCCGCGATGCTGCGCTATTTCCAGGCTGCGAGCGGGGACTTCACTGCTCTGCTGTCTCCTGCAAGAACTGGCTCAAGAAATTTGCCTCG AAAACCAACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTG CTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGAC GATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATC CTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATT ATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTA GCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAA GTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCA GGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTAC AACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAA CTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGC TGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGG AAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTG GAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGAC AGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAAC AGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTA GAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCT GTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAAATGTGGAAGAGCTGATACCAGCATTGGATTTACTTTGCTCGGCA ATTAGAGAAAGTTATTCTGAACCCCAAAGCAAACACTTTTCAGAACAATTGCTTAATCTTACACTGTCTTTCCTTAACAACCAAATAAAG GAGCTTTTCATTCACACTGAAGAACTAGATGAACATCTGCAAAAAGGAGTGAACATTTTGACTAGCTACATTAATGAACTTCGAACCTTC ATGATAAAGTTTCCTTGGAAGCTAACAGATGCTATAGATGAATATGATGTACATGAAAATGTCCCCAAAGTAAAGGAGAGCAATATATGG AAGAAACTCAGCTTTGAGGAAGTTATTGCCAGCGCCATTTTAAACAACAAAATACCAGAGGCACAGACTTTCTTCAGGATTGATAGTCAT TCTGCTCAAAAACTTGAGGAGCTTATTGGCATAGGCCTAAATTTGGTCTTTGACAATTTAAAAAAGAACAATATAAAGGAAGCCTCTGAA CTTTTGAAGAATATGGGGTTTGATGTAAAAGGCCAATTGCTCAAGATCTGCTTCTATACAACTAATAAAAATATACGTGACTTTTTGGTT GAAATTTTAAAAGAAAAAAATTATTTTTCTGAAAAAGAGAAAAGAACTATAGACTTCGTGCATCAAGTTGAGAAGCTTTATTTGGGACAT TTCCAAGAAAATATGCAAATCCAGTCATTTCCCAGGTACTGGATAAAGGAACAAGATTTTTTCAAGCACAAGTCTGTTTTGGACTCATTC CTGAAATATGATTGTAAAGATGAATTTAACAAACAGGACCATAGAATTGTGTTAAATTGGGCTCTGTGGTGGGATCAACTAACACAAGAA TCCATCCTTCTCCCCAGGATAAGTCCAGAAGAATACAAATCATATTCCCCTGAAGCCCTCTGGAGATACCTCACAGCTCGCCATGATTGG TTAAACATTATCTTATGGATTGGAGAATTTCAAACCCAGCATAGTTATGCTTCACTTCAGCAGAACAAATGGCCCCTTCTGACTGTTGAT GTTATTAACCAGAATACTTCCTGTAACAACTACATGAGGAATGAAATTTTAGATAAGCTGGCCAGGAATGGGGTTTTTTTGGCATCTGAA CTGGAAGACTTTGAATGCTTCCTCCTAAGACTGAGCCGTATTGGAGGTGTAATACAGGATACCCTCCCTGTTCAAAACTACAAGACCAAA GAAGGTTGGGATTTCCATTCTCAATTCATTCTCTATTGTTTGGAGCACAGTCTGCAGCATCTTCTTTATGTCTACCTTGACTGTTACAAA CTTAGTCCTGAAAATTGTCCCTTTTTGGAAAAAAAAGAGTTACATGAAGCACACCCTTGGTTTGAATTTTTAGTTCAGTGTCGACAAGTT GCCAGTAACTTAACAGATCCCAAACTGATCTTCCAGGCTAGCCTTGCAAATGCTCAGATTTTGATTCCCACCAATCAGGCCAGTGTAAGC AGTATGCTATTGGAAGGACATACCCTCCTGGCCCTTGCTACTACAATGTATTCTCCTGGGGGTGTCAGTCAGGTTGTTCAGAATGAAGAA AATGAAAACTGTTTGAAGAAAGTGGATCCCCAGCTATTGAAGATGGCATTAACTCCTTACCCCAAGCTAAAAACTGCTCTCTTCCCACAG TGCACTCCTCCTAGTGTCCTGCCATCTGATATTACAATCTACCACCTTATTCAGTCATTATCACCCTTTGATCCTAGCAGATTGTTTGGC TGGCAGTCTGCTAACACACTAGCTATAGGAGATGCATGGAGTCATCTCCCACATTTCTCTAGCCCTGACCTGGTTAATAAATATGCTATA GTGGAACGTCTGAATTTTGCTTATTATTTACATAATGGGCGGCCATCATTTGCATTTGGTACTTTTCTGGTCCAGGAATTAATCAAGAGC AAGACTCCCAAGCAGCTGATCCAGCAAGTAGGCAATGAAGCCTATGTTATAGGGCTCTCCTCCTTCCACATACCTTCAATAGGAGCTGCA TGTGTTTGTTTCTTAGAATTGCTTGGCCTTGACAGCCTCAAGCTCAGAGTTGATATGAAAGTGGCCAATATAATTTTGAGCTACAAGTGC AGAAATGAAGATGCTCAGTACAGCTTTATCAGAGAGTCTGTAGCCGAAAAACTATCTAAACTAGCTGATGGTGAAAAGACAACCACAGAA GAATTGCTTGTTCTCTTAGAAGAAGGTACATGGAACAGCATTCAGCAACAGGAAATAAAGAGGTTATCCAGTGAATCTAGCAGCCAATGG GCATTAGTGGTGCAGTTCTGCAGGCTACACAATATGAAACTAAGCATATCTTACCTTAGAGAATGTGCCAAAGCAAATGATTGGCTGCAG TTCATTATTCACAGCCAACTCCACAACTACCACCCAGCAGAGGTGAAATCCCTTATCCAGTACTTCAGCCCAGTCATTCAAGACCACTTA AGGCTGGCTTTTGAGAACTTGCCCTCAGTGCCCACCTCCAAAATGGACAGCGATCAAGTCTGCAATAAGTGCCCCCAGGAACTTCAAGGA AGCAAACAAGAGATGACCGATTTATTTGAAATTCTGCTCCAATGCTCAGAGGAGCCAGACTCCTGGCACTGGCTTCTGGTTGAAGCAGTG AAACAACAGGCCCCTATCCTCAGTGTTCTGGCCTCATGTCTCCAGGGTGCCAGTGCCATTTCTTGTCTCTGTGTTTGGATCATCACTTCT GTGGAGGACAATGTTGCAACTGAAGCAATGGGACACATTCAGGACTCAACAGAGGACCATACCTGGAACCTTGAGGATCTTTCAGTCATC TGGAGAACATTATTAACAAGACAAAAGAGCAAAACTCTCATCAGAGGTTTCCAGCTTTTCTTTAAGGATTCCCCGTTACTACTGGTGATG GAGATGTATGAACTGTGTATGTTCTTCAGGAATTATAAAGAAGCTGAAGCTAAACTTCTGGAGTTTCAGAAGAGCCTTGAAACGCTTAAC ACAGCAGCCACAAAGGTCCACCCTGTCATCCCTGCCATGTGGCTGGAGGATCAGGTGTGTTTCCTTTTGAAGCTTATGCTACAGCAGTGT AAGACCCAGTATGAGCTGGGGAAGCTTTTACAGCTCTTTGTTGAAAGAGAGCATCTCTTCTCTGATGGTCCAGATGTGAAAAAGCTTTGC ATCCTTTGCCAGATTTTGAAGGATACATCCATAGCCATTAATCATACAATTATTACCAGCTACAGCATTGAGAATCTTCAGCATGAATGT AGATCTATTTTGGAAAGACTGCAGACAGATGGACAATTCGCTTTGGCCAGGAGGGTAGCAGAATTAGCTGAGTTACCTGTGGACAACTTG GTTATTAAAGAGATAACACAGGAAATGCAGACCCTAAAACACATTGAACAGTGGTCACTAAAACAAGCAAGAATTGACTTCTGGAAAAAA TGCCATGAGAATTTTAAGAAAAATTCAATTTCAAGCAAAGCAGCTTCTTCCTTTTTCTCAACCCAGGCCCATGTGGCATGTGAGCACCCA ACTGGATGGAGCAGCATGGAGGAGCGCCATCTGCTGCTCACCTTGGCAGGGCACTGGCTTGCCCAGGAGGACGTGGTGCCCTTGGATAAG CTGGAGGAGCTGGAGAAGCAGATCTGGCTGTGCCGCATCACCCAGCACACTCTTGGAAGAAATCAGGAGGAAACAGAGCCCAGATTTTCT CGACAGATCTCAACTAGTGGTGAACTTTCCTTTGATAGTTTAGCCAGTGAGTTTTCCTTCTCCAAGTTGGCTGCTCTGAACACATCAAAA TACTTAGAACTTAACAGCCTTCCATCCAAAGAGACATGCGAGAATAGATTGGATTGGAAAGAGCAGGAGTCACTAAACTTTTTGATTGGG CGCCTACTGGATGATGGCTGTGTGCATGAAGCAAGTAGAGTATGCCGGTATTTTCATTTTTATAATCCAGATGTCGCCTTGGTATTGCAC TGCAGAGCACTGGCCTCAGGGGAAGCTAGTATGGAGGATCTGCACCCAGAGATCCATGCTCTCCTACAAAGTGCTGAGCTGCTTGAGGAA GAAGCACCCGACATTCCCCTAAGGAGAGTCCACAGCACTTCAAGTCTGGATAGTCAGAAGTTTGTGACAGTGCCCTCCAGTAATGAAGTG GTAACTAACCTGGAAGTGCTGACAAGCAAATGCCTCCATGGGAAGAACTACTGTCGACAGGTCCTCTGTCTGTATGATCTTGCCAAGGAG TTGGGCTGTTCCTACACAGATGTTGCTGCTCAGGATGGTGAAGCCATGCTCCGGAAAATCTTGGCCTCTCAGCAGCCTGACCGATGCAAA CGAGCCCAGGCCTTCATCAGCACACAGGGCCTTAAGCCAGATACTGTGGCTGAACTCGTGGCAGAAGAGGTGACACGGGAGCTGCTTACT TCATCACAGGGAACAGGACATAAGCAGATGTTCAACCCAACAGAGGAAAGCCAGACATTTCTTCAGCTGACCACTCTGTGTCAAGACCGC ACATTGGTAGGCATGAAGTTGTTGGATAAGATTTCCTCCGTTCCCCATGGGGAACTGTCTTGCACCACAGAGCTCCTGATCCTGGCCCAT CATTGCTTCACCCTGACGTGCCACATGGAGGGCATCATCCGAGTCCTACAGGCCGCCCACATGCTCACAGATAACCACCTGGCCCCCAGT GAGGAGTATGGGCTGGTGGTACGGCTCCTCACTGGCATTGGAAGGTACAACGAGATGACATACATATTTGATTTGCTGCATAAAAAGCAC TACTTTGAAGTGCTAATGAGGAAGAAGTTGGATCCGAGTGGTACCCTGAAAACAGCCCTGCTGGACTACATCAAACGCTGCCGTCCTGGA GACAGTGAAAAGCACAATATGATTGCCCTGTGCTTCAGCATGTGCCGGGAGATTGGCGAGAACCACGAGGCAGCTGCCCGCATCCAACTG AAATTGATTGAGTCTCAGCCCTGGGATATAAACAACATCAGCCTACTGACATGGTCATGGAAAACCTGAAGAAATTACTCACATATTGTG AAGATGTTTACCTGTATTACAAGTTGGCATACGAACACAAGTTTTATGAAATTGTAAATGTGCTTCTGAAGGACCCTCAGACAGGTTGCT >72634_72634_2_RBFA-SPG11_RBFA_chr18_77794653_ENST00000262197_SPG11_chr15_44952814_ENST00000427534_length(amino acids)=2232AA_BP=53 MWAAAGGLWRSRAGLRALFRSRDAALFPGCERGLHCSAVSCKNWLKKFASKTNFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDG RCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGIL FVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILE DLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMH GQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFV LTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSS HLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNNQIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTD AIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRIDSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVK GQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLYLGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFN KQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNN YMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNYKTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLE KKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDP QLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSRLFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYL HNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSIGAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFI RESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESSSQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNY HPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQELQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVL ASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDLSVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFR NYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLMLQQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTS IAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPVDNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSI SSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVPLDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELS FDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNFLIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEAS MEDLHPEIHALLQSAELLEEEAPDIPLRRVHSTSSLDSQKFVTVPSSNEVVTNLEVLTSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAA QDGEAMLRKILASQQPDRCKRAQAFISTQGLKPDTVAELVAEEVTRELLTSSQGTGHKQMFNPTEESQTFLQLTTLCQDRTLVGMKLLDK ISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLQAAHMLTDNHLAPSEEYGLVVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKL -------------------------------------------------------------- >72634_72634_3_RBFA-SPG11_RBFA_chr18_77794653_ENST00000262197_SPG11_chr15_44952814_ENST00000535302_length(transcript)=7191nt_BP=188nt CCTGCTCGCTCCGGGTCCCGGCGCCGCGCCATGTGGGCTGCGGCGGGCGGGCTGTGGCGCTCCCGCGCGGGTCTCCGGGCCCTGTTCCGT AGCCGCGATGCTGCGCTATTTCCAGGCTGCGAGCGGGGACTTCACTGCTCTGCTGTCTCCTGCAAGAACTGGCTCAAGAAATTTGCCTCG AAAACCAACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTG CTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGAC GATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATC CTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATT ATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTA GCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAA GTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCA GGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTAC AACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAA CTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGC TGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGG AAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTG GAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGAC AGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAAC AGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTA GAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCT GTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAAATGTGGAAGAGCTGATACCAGCATTGGATTTACTTTGCTCGGCA ATTAGAGAAAGTTATTCTGAACCCCAAAGCAAACACTTTTCAGAACAATTGCTTAATCTTACACTGTCTTTCCTTAACAACCAAATAAAG GAGCTTTTCATTCACACTGAAGAACTAGATGAACATCTGCAAAAAGGAGTGAACATTTTGACTAGCTACATTAATGAACTTCGAACCTTC ATGATAAAGTTTCCTTGGAAGCTAACAGATGCTATAGATGAATATGATGTACATGAAAATGTCCCCAAAGTAAAGGAGAGCAATATATGG AAGAAACTCAGCTTTGAGGAAGTTATTGCCAGCGCCATTTTAAACAACAAAATACCAGAGGCACAGACTTTCTTCAGGATTGATAGTCAT TCTGCTCAAAAACTTGAGGAGCTTATTGGCATAGGCCTAAATTTGGTCTTTGACAATTTAAAAAAGAACAATATAAAGGAAGCCTCTGAA CTTTTGAAGAATATGGGGTTTGATGTAAAAGGCCAATTGCTCAAGATCTGCTTCTATACAACTAATAAAAATATACGTGACTTTTTGGTT GAAATTTTAAAAGAAAAAAATTATTTTTCTGAAAAAGAGAAAAGAACTATAGACTTCGTGCATCAAGTTGAGAAGCTTTATTTGGGACAT TTCCAAGAAAATATGCAAATCCAGTCATTTCCCAGGTACTGGATAAAGGAACAAGATTTTTTCAAGCACAAGTCTGTTTTGGACTCATTC CTGAAATATGATTGTAAAGATGAATTTAACAAACAGGACCATAGAATTGTGTTAAATTGGGCTCTGTGGTGGGATCAACTAACACAAGAA TCCATCCTTCTCCCCAGGATAAGTCCAGAAGAATACAAATCATATTCCCCTGAAGCCCTCTGGAGATACCTCACAGCTCGCCATGATTGG TTAAACATTATCTTATGGATTGGAGAATTTCAAACCCAGCATAGTTATGCTTCACTTCAGCAGAACAAATGGCCCCTTCTGACTGTTGAT GTTATTAACCAGAATACTTCCTGTAACAACTACATGAGGAATGAAATTTTAGATAAGCTGGCCAGGAATGGGGTTTTTTTGGCATCTGAA CTGGAAGACTTTGAATGCTTCCTCCTAAGACTGAGCCGTATTGGAGGTGTAATACAGGATACCCTCCCTGTTCAAAACTACAAGACCAAA GAAGGTTGGGATTTCCATTCTCAATTCATTCTCTATTGTTTGGAGCACAGTCTGCAGCATCTTCTTTATGTCTACCTTGACTGTTACAAA CTTAGTCCTGAAAATTGTCCCTTTTTGGAAAAAAAAGAGTTACATGAAGCACACCCTTGGTTTGAATTTTTAGTTCAGTGTCGACAAGTT GCCAGTAACTTAACAGATCCCAAACTGATCTTCCAGGCTAGCCTTGCAAATGCTCAGATTTTGATTCCCACCAATCAGGCCAGTGTAAGC AGTATGCTATTGGAAGGACATACCCTCCTGGCCCTTGCTACTACAATGTATTCTCCTGGGGGTGTCAGTCAGGTTGTTCAGAATGAAGAA AATGAAAACTGTTTGAAGAAAGTGGATCCCCAGCTATTGAAGATGGCATTAACTCCTTACCCCAAGCTAAAAACTGCTCTCTTCCCACAG TGCACTCCTCCTAGTGTCCTGCCATCTGATATTACAATCTACCACCTTATTCAGTCATTATCACCCTTTGATCCTAGCAGATTGTTTGGC TGGCAGTCTGCTAACACACTAGCTATAGGAGATGCATGGAGTCATCTCCCACATTTCTCTAGCCCTGACCTGGTTAATAAATATGCTATA GTGGAACGTCTGAATTTTGCTTATTATTTACATAATGGGCGGCCATCATTTGCATTTGGTACTTTTCTGGTCCAGGAATTAATCAAGAGC AAGACTCCCAAGCAGCTGATCCAGCAAGTAGGCAATGAAGCCTATGTTATAGGGCTCTCCTCCTTCCACATACCTTCAATAGGAGCTGCA TGTGTTTGTTTCTTAGAATTGCTTGGCCTTGACAGCCTCAAGCTCAGAGTTGATATGAAAGTGGCCAATATAATTTTGAGCTACAAGTGC AGAAATGAAGATGCTCAGTACAGCTTTATCAGAGAGTCTGTAGCCGAAAAACTATCTAAACTAGCTGATGGTGAAAAGACAACCACAGAA GAATTGCTTGTTCTCTTAGAAGAAGGTACATGGAACAGCATTCAGCAACAGGAAATAAAGAGGTTATCCAGTGAATCTAGCAGCCAATGG GCATTAGTGGTGCAGTTCTGCAGGCTACACAATATGAAACTAAGCATATCTTACCTTAGAGAATGTGCCAAAGCAAATGATTGGCTGCAG TTCATTATTCACAGCCAACTCCACAACTACCACCCAGCAGAGGTGAAATCCCTTATCCAGTACTTCAGCCCAGTCATTCAAGACCACTTA AGGCTGGCTTTTGAGAACTTGCCCTCAGTGCCCACCTCCAAAATGGACAGCGATCAAGTCTGCAATAAGTGCCCCCAGGAACTTCAAGGA AGCAAACAAGAGATGACCGATTTATTTGAAATTCTGCTCCAATGCTCAGAGGAGCCAGACTCCTGGCACTGGCTTCTGGTTGAAGCAGTG AAACAACAGGCCCCTATCCTCAGTGTTCTGGCCTCATGTCTCCAGGGTGCCAGTGCCATTTCTTGTCTCTGTGTTTGGATCATCACTTCT GTGGAGGACAATGTTGCAACTGAAGCAATGGGACACATTCAGGACTCAACAGAGGACCATACCTGGAACCTTGAGGATCTTTCAGTCATC TGGAGAACATTATTAACAAGACAAAAGAGCAAAACTCTCATCAGAGGTTTCCAGCTTTTCTTTAAGGATTCCCCGTTACTACTGGTGATG GAGATGTATGAACTGTGTATGTTCTTCAGGAATTATAAAGAAGCTGAAGCTAAACTTCTGGAGTTTCAGAAGAGCCTTGAAACGCTTAAC ACAGCAGCCACAAAGGTCCACCCTGTCATCCCTGCCATGTGGCTGGAGGATCAGGTGTGTTTCCTTTTGAAGCTTATGCTACAGCAGTGT AAGACCCAGTATGAGCTGGGGAAGCTTTTACAGCTCTTTGTTGAAAGAGAGCATCTCTTCTCTGATGGTCCAGATGTGAAAAAGCTTTGC ATCCTTTGCCAGATTTTGAAGGATACATCCATAGCCATTAATCATACAATTATTACCAGCTACAGCATTGAGAATCTTCAGCATGAATGT AGATCTATTTTGGAAAGACTGCAGACAGATGGACAATTCGCTTTGGCCAGGAGGGTAGCAGAATTAGCTGAGTTACCTGTGGACAACTTG GTTATTAAAGAGATAACACAGGAAATGCAGACCCTAAAACACATTGAACAGTGGTCACTAAAACAAGCAAGAATTGACTTCTGGAAAAAA TGCCATGAGAATTTTAAGAAAAATTCAATTTCAAGCAAAGCAGCTTCTTCCTTTTTCTCAACCCAGGCCCATGTGGCATGTGAGCACCCA ACTGGATGGAGCAGCATGGAGGAGCGCCATCTGCTGCTCACCTTGGCAGGGCACTGGCTTGCCCAGGAGGACGTGGTGCCCTTGGATAAG CTGGAGGAGCTGGAGAAGCAGATCTGGCTGTGCCGCATCACCCAGCACACTCTTGGAAGAAATCAGGAGGAAACAGAGCCCAGATTTTCT CGACAGATCTCAACTAGTGGTGAACTTTCCTTTGATAGTTTAGCCAGTGAGTTTTCCTTCTCCAAGTTGGCTGCTCTGAACACATCAAAA TACTTAGAACTTAACAGCCTTCCATCCAAAGAGACATGCGAGAATAGATTGGATTGGAAAGAGCAGGAGTCACTAAACTTTTTGATTGGG CGCCTACTGGATGATGGCTGTGTGCATGAAGCAAGTAGAGTATGCCGGTATTTTCATTTTTATAATCCAGATGTCGCCTTGGTATTGCAC TGCAGAGCACTGGCCTCAGGGGAAGCTAGTATGGAGGATCTGCACCCAGAGATCCATGCTCTCCTACAAAGTGCTGAGCTGCTTGAGGAA GAAGCACCCGACATTCCCCTAAGGAGAGTCCACAGCAGACATAAGCAGATGTTCAACCCAACAGAGGAAAGCCAGACATTTCTTCAGCTG ACCACTCTGTGTCAAGACCGCACATTGGTAGGCATGAAGTTGTTGGATAAGATTTCCTCCGTTCCCCATGGGGAACTGTCTTGCACCACA GAGCTCCTGATCCTGGCCCATCATTGCTTCACCCTGACGTGCCACATGGAGGGCATCATCCGAGTCCTACAGGCCGCCCACATGCTCACA GATAACCACCTGGCCCCCAGTGAGGAGTATGGGCTGGTGGTACGGCTCCTCACTGGCATTGGAAGGTACAACGAGATGACATACATATTT GATTTGCTGCATAAAAAGCACTACTTTGAAGTGCTAATGAGGAAGAAGTTGGATCCGAGTGGTACCCTGAAAACAGCCCTGCTGGACTAC ATCAAACGCTGCCGTCCTGGAGACAGTGAAAAGCACAATATGATTGCCCTGTGCTTCAGCATGTGCCGGGAGATTGGCGAGAACCACGAG GCAGCTGCCCGCATCCAACTGAAATTGATTGAGTCTCAGCCCTGGGAGGACAGCCTCAAGGATGGGCACCAGCTGAAACAACTGCTGCTG AAGGCCCTGACTCTGATGTTGGATGCAGCAGAGAGTTATGCCAAGGACTCCTGTGTGCGACAGGCCCAGCACTGTCAGCGGCTCACCAAG TTGATAACTCTGCAGATTCACTTTCTGAACACTGGCCAGAACACAATGCTCATCAACTTGGGCCGCCACAAGCTGATGGACTGTATTCTG GCCCTACCTCGGTTCTACCAGGCTTCTATTGTGGCTGAGGCCTACGATTTTGTTCCAGATTGGGCTGAAATTTTATACCAGCAAGTGATT CTTAAAGGAGACTTTAATTACTTGGAAGAATTTAAGCAGCAAAGGTTATTAAAGTCCAGTATATTTGAAGAGATTTCCAAAAAATATAAA CAACATCAGCCTACTGACATGGTCATGGAAAACCTGAAGAAATTACTCACATATTGTGAAGATGTTTACCTGTATTACAAGTTGGCATAC GAACACAAGTTTTATGAAATTGTAAATGTGCTTCTGAAGGACCCTCAGACAGGTTGCTGTCTAAAGGACATGCTAGCAGGTTAGATGATT TCATAGGTGTCTGTTTTCTTGTACTGTTAGCAGATTCTGACAGATGTGATGAGAAGAAGAATGCATTGGAGATCTTTGCTAAAGTTGAAC AATCCCGGTACTGTACCATATCAGTCCTTTGTGGGTAGTAGGTAGCAAGTAAGAAACTTTTCAGGAGGAAATTCCTATTTAAAATAGATT >72634_72634_3_RBFA-SPG11_RBFA_chr18_77794653_ENST00000262197_SPG11_chr15_44952814_ENST00000535302_length(amino acids)=2297AA_BP=53 MWAAAGGLWRSRAGLRALFRSRDAALFPGCERGLHCSAVSCKNWLKKFASKTNFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDG RCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGIL FVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILE DLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMH GQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFV LTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSS HLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNNQIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTD AIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRIDSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVK GQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLYLGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFN KQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNN YMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNYKTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLE KKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDP QLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSRLFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYL HNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSIGAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFI RESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESSSQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNY HPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQELQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVL ASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDLSVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFR NYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLMLQQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTS IAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPVDNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSI SSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVPLDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELS FDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNFLIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEAS MEDLHPEIHALLQSAELLEEEAPDIPLRRVHSRHKQMFNPTEESQTFLQLTTLCQDRTLVGMKLLDKISSVPHGELSCTTELLILAHHCF TLTCHMEGIIRVLQAAHMLTDNHLAPSEEYGLVVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSE KHNMIALCFSMCREIGENHEAAARIQLKLIESQPWEDSLKDGHQLKQLLLKALTLMLDAAESYAKDSCVRQAQHCQRLTKLITLQIHFLN TGQNTMLINLGRHKLMDCILALPRFYQASIVAEAYDFVPDWAEILYQQVILKGDFNYLEEFKQQRLLKSSIFEEISKKYKQHQPTDMVME -------------------------------------------------------------- >72634_72634_4_RBFA-SPG11_RBFA_chr18_77794653_ENST00000262197_SPG11_chr15_44952814_ENST00000558319_length(transcript)=6326nt_BP=188nt CCTGCTCGCTCCGGGTCCCGGCGCCGCGCCATGTGGGCTGCGGCGGGCGGGCTGTGGCGCTCCCGCGCGGGTCTCCGGGCCCTGTTCCGT AGCCGCGATGCTGCGCTATTTCCAGGCTGCGAGCGGGGACTTCACTGCTCTGCTGTCTCCTGCAAGAACTGGCTCAAGAAATTTGCCTCG AAAACCAACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTG CTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGAC GATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATC CTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATT ATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTA GCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAA GTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCA GGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTAC AACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAA CTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGC TGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGG AAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTG GAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGAC AGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAAC AGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTA GAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCT GTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAAATGTGGAAGAGCTGATACCAGCATTGGATTTACTTTGCTCGGCA ATTAGAGAAAGTTATTCTGAACCCCAAAGCAAACACTTTTCAGAACAATTGCTTAATCTTACACTGTCTTTCCTTAACAACCAAATAAAG GAGCTTTTCATTCACACTGAAGAACTAGATGAACATCTGCAAAAAGGAGTGAACATTTTGACTAGCTACATTAATGAACTTCGAACCTTC ATGATAAAGTTTCCTTGGAAGCTAACAGATGCTATAGATGAATATGATGTACATGAAAATGTCCCCAAAGTAAAGGAGAGCAATATATGG AAGAAACTCAGCTTTGAGGAAGTTATTGCCAGCGCCATTTTAAACAACAAAATACCAGAGGCACAGACTTTCTTCAGGATTGATAGTCAT TCTGCTCAAAAACTTGAGGAGCTTATTGGCATAGGCCTAAATTTGGTCTTTGACAATTTAAAAAAGAACAATATAAAGGAAGCCTCTGAA CTTTTGAAGAATATGGGGTTTGATGTAAAAGGCCAATTGCTCAAGATCTGCTTCTATACAACTAATAAAAATATACGTGACTTTTTGGTT GAAATTTTAAAAGAAAAAAATTATTTTTCTGAAAAAGAGAAAAGAACTATAGACTTCGTGCATCAAGTTGAGAAGCTTTATTTGGGACAT TTCCAAGAAAATATGCAAATCCAGTCATTTCCCAGGTACTGGATAAAGGAACAAGATTTTTTCAAGCACAAGTCTGTTTTGGACTCATTC CTGAAATATGATTGTAAAGATGAATTTAACAAACAGGACCATAGAATTGTGTTAAATTGGGCTCTGTGGTGGGATCAACTAACACAAGAA TCCATCCTTCTCCCCAGGATAAGTCCAGAAGAATACAAATCATATTCCCCTGAAGCCCTCTGGAGATACCTCACAGCTCGCCATGATTGG TTAAACATTATCTTATGGATTGGAGAATTTCAAACCCAGCATAGTTATGCTTCACTTCAGCAGAACAAATGGCCCCTTCTGACTGTTGAT GTTATTAACCAGAATACTTCCTGTAACAACTACATGAGGAATGAAATTTTAGATAAGCTGGCCAGGAATGGGGTTTTTTTGGCATCTGAA CTGGAAGACTTTGAATGCTTCCTCCTAAGACTGAGCCGTATTGGAGGTGTAATACAGGATACCCTCCCTGTTCAAAACTACAAGACCAAA GAAGGTTGGGATTTCCATTCTCAATTCATTCTCTATTGTTTGGAGCACAGTCTGCAGCATCTTCTTTATGTCTACCTTGACTGTTACAAA CTTAGTCCTGAAAATTGTCCCTTTTTGGAAAAAAAAGAGTTACATGAAGCACACCCTTGGTTTGAATTTTTAGTTCAGTGTCGACAAGTT GCCAGTAACTTAACAGATCCCAAACTGATCTTCCAGGCTAGCCTTGCAAATGCTCAGATTTTGATTCCCACCAATCAGGCCAGTGTAAGC AGTATGCTATTGGAAGGACATACCCTCCTGGCCCTTGCTACTACAATGTATTCTCCTGGGGGTGTCAGTCAGGTTGTTCAGAATGAAGAA AATGAAAACTGTTTGAAGAAAGTGGATCCCCAGCTATTGAAGATGGCATTAACTCCTTACCCCAAGCTAAAAACTGCTCTCTTCCCACAG TGCACTCCTCCTAGTGTCCTGCCATCTGATATTACAATCTACCACCTTATTCAGTCATTATCACCCTTTGATCCTAGCAGATTGTTTGGC TGGCAGTCTGCTAACACACTAGCTATAGGAGATGCATGGAGTCATCTCCCACATTTCTCTAGCCCTGACCTGGTTAATAAATATGCTATA GTGGAACGTCTGAATTTTGCTTATTATTTACATAATGGGCGGCCATCATTTGCATTTGGTACTTTTCTGGTCCAGGAATTAATCAAGAGC AAGACTCCCAAGCAGCTGATCCAGCAAGTAGGCAATGAAGCCTATGTTATAGGGCTCTCCTCCTTCCACATACCTTCAATAGGAGCTGCA TGTGTTTGTTTCTTAGAATTGCTTGGCCTTGACAGCCTCAAGCTCAGAGTTGATATGAAAGTGGCCAATATAATTTTGAGCTACAAGTGC AGAAATGAAGATGCTCAGTACAGCTTTATCAGAGAGTCTGTAGCCGAAAAACTATCTAAACTAGCTGATGGTGAAAAGACAACCACAGAA GAATTGCTTGTTCTCTTAGAAGAAGGTACATGGAACAGCATTCAGCAACAGGAAATAAAGAGGTTATCCAGTGAATCTAGCAGCCAATGG GCATTAGTGGTGCAGTTCTGCAGGCTACACAATATGAAACTAAGCATATCTTACCTTAGAGAATGTGCCAAAGCAAATGATTGGCTGCAG TTCATTATTCACAGCCAACTCCACAACTACCACCCAGCAGAGGTGAAATCCCTTATCCAGTACTTCAGCCCAGTCATTCAAGACCACTTA AGGCTGGCTTTTGAGAACTTGCCCTCAGTGCCCACCTCCAAAATGGACAGCGATCAAGTCTGCAATAAGTGCCCCCAGGAACTTCAAGGA AGCAAACAAGAGATGACCGATTTATTTGAAATTCTGCTCCAATGCTCAGAGGAGCCAGACTCCTGGCACTGGCTTCTGGTTGAAGCAGTG AAACAACAGGCCCCTATCCTCAGTGTTCTGGCCTCATGTCTCCAGGGTGCCAGTGCCATTTCTTGTCTCTGTGTTTGGATCATCACTTCT GTGGAGGACAATGTTGCAACTGAAGCAATGGGACACATTCAGGACTCAACAGAGGACCATACCTGGAACCTTGAGGATCTTTCAGTCATC TGGAGAACATTATTAACAAGACAAAAGAGCAAAACTCTCATCAGAGGTTTCCAGCTTTTCTTTAAGGATTCCCCGTTACTACTGGTGATG GAGATGTATGAACTGTGTATGTTCTTCAGGAATTATAAAGAAGCTGAAGCTAAACTTCTGGAGTTTCAGAAGAGCCTTGAAACGCTTAAC ACAGCAGCCACAAAGGTCCACCCTGTCATCCCTGCCATGTGGCTGGAGGATCAGGTGTGTTTCCTTTTGAAGCTTATGCTACAGCAGTGT AAGACCCAGTATGAGCTGGGGAAGCTTTTACAGCTCTTTGTTGAAAGAGAGCATCTCTTCTCTGATGGTCCAGATGTGAAAAAGCTTTGC ATCCTTTGCCAGATTTTGAAGGATACATCCATAGCCATTAATCATACAATTATTACCAGCTACAGCATTGAGAATCTTCAGCATGAATGT AGATCTATTTTGGAAAGACTGCAGACAGATGGACAATTCGCTTTGGCCAGGAGGGTAGCAGAATTAGCTGAGTTACCTGTGGACAACTTG GTTATTAAAGAGATAACACAGGAAATGCAGACCCTAAAACACATTGAACAGTGGTCACTAAAACAAGCAAGAATTGACTTCTGGAAAAAA TGCCATGAGAATTTTAAGAAAAATTCAATTTCAAGCAAAGCAGCTTCTTCCTTTTTCTCAACCCAGGCCCATGTGGCATGTGAGCACCCA ACTGGATGGAGCAGCATGGAGGAGCGCCATCTGCTGCTCACCTTGGCAGGGCACTGGCTTGCCCAGGAGGACGTGGTGCCCTTGGATAAG CTGGAGGAGCTGGAGAAGCAGATCTGGCTGTGCCGCATCACCCAGCACACTCTTGGAAGAAATCAGGAGGAAACAGAGCCCAGATTTTCT CGACAGATCTCAACTAGTGGTGAACTTTCCTTTGATAGTTTAGCCAGTGAGTTTTCCTTCTCCAAGTTGGCTGCTCTGAACACATCAAAA TACTTAGAACTTAACAGCCTTCCATCCAAAGAGACATGCGAGAATAGATTGGATTGGAAAGAGCAGGAGTCACTAAACTTTTTGATTGGG CGCCTACTGGATGATGGCTGTGTGCATGAAGCAAGTAGAGTATGCCGGTATTTTCATTTTTATAATCCAGATGTCGCCTTGGTATTGCAC TGCAGAGCACTGGCCTCAGGGGAAGCTAGTATGGAGGATCTGCACCCAGAGATCCATGCTCTCCTACAAAGTGCTGAGCTGCTTGAGGAA GAAGCACCCGACATTCCCCTAAGGAGAGTCCACAGCACTTCAAGTCTGGATAGTCAGAAGTTTGTGACAGTGCCCTCCAGTAATGAAGTG GTAACTAACCTGGAAGTGCTGACAAGCAAATGCCTCCATGGGAAGAACTACTGTCGACAGGTCCTCTGTCTGTATGATCTTGCCAAGGAG TTGGGCTGTTCCTACACAGATGTTGCTGCTCAGGATGGTGAAGCCATGCTCCGGAAAATCTTGGCCTCTCAGCAGCCTGACCGATGCAAA CGAGCCCAGGCCTTCATCAGCACACAGGGCCTTAAGCCAGATACTGTGGCTGAACTCGTGGCAGAAGAGGTGACACGGGAGCTGCTTACT TCATCACAGGGAACAGGTGCCCTACCCCCCGGGGATTCCCAACCTCTCTGACAGCATTCTCTAGTTCCCAGTGTTAAGGATTTGGATGTT GTGCTTATATACATCCTGTATGTGGTTCTCTCAAGTTTCTGGATTGCAGTAATGTATTTTGTTTAAATAAAACAAAATACATGCTTTATT >72634_72634_4_RBFA-SPG11_RBFA_chr18_77794653_ENST00000262197_SPG11_chr15_44952814_ENST00000558319_length(amino acids)=2046AA_BP=53 MWAAAGGLWRSRAGLRALFRSRDAALFPGCERGLHCSAVSCKNWLKKFASKTNFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDG RCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGIL FVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILE DLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMH GQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFV LTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSS HLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNNQIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTD AIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRIDSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVK GQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLYLGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFN KQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNN YMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNYKTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLE KKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDP QLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSRLFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYL HNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSIGAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFI RESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESSSQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNY HPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQELQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVL ASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDLSVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFR NYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLMLQQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTS IAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPVDNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSI SSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVPLDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELS FDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNFLIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEAS MEDLHPEIHALLQSAELLEEEAPDIPLRRVHSTSSLDSQKFVTVPSSNEVVTNLEVLTSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAA -------------------------------------------------------------- >72634_72634_5_RBFA-SPG11_RBFA_chr18_77794653_ENST00000306735_SPG11_chr15_44952814_ENST00000261866_length(transcript)=7796nt_BP=296nt ACACGCCGCCTGCCAGGCGTGAGTCTTCCTCCCGCTCTGCGCCGTCGCCCCGCCCACACGCCGCCACCCTCGCGTCAGTTGTCGCTCCGC GCCTGCGCCCGTTGTCTCCCTGCTCGCTCCGGGTCCCGGCGCCGCGCCATGTGGGCTGCGGCGGGCGGGCTGTGGCGCTCCCGCGCGGGT CTCCGGGCCCTGTTCCGTAGCCGCGATGCTGCGCTATTTCCAGGCTGCGAGCGGGGACTTCACTGCTCTGCTGTCTCCTGCAAGAACTGG CTCAAGAAATTTGCCTCGAAAACCAACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTT GGTGAAAATTATGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCA TTGCAAAAGCTCATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTC ATCAACAAATGTGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCA CAGGCAGTGGACATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTT GTGGATGGTACATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCT TCATTTACTTCACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTG TATTTCAGGCAACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGAT CCTGTTAACTCTGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAA ACAATAAAGAACTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCAC AGTACAAGTGTGCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGT GATCCAGGAAGATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCA CTGTTTACTTGGGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACA AAGTGTATTCCTGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACT CAAGAAGAGTTTTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCA ATTCCCATACATGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAAT CCATCCTCAAAATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAAATGTGGAAGAGCTGATACCAGCATTG GATTTACTTTGCTCGGCAATTAGAGAAAGTTATTCTGAACCCCAAAGCAAACACTTTTCAGAACAATTGCTTAATCTTACACTGTCTTTC CTTAACAACCAAATAAAGGAGCTTTTCATTCACACTGAAGAACTAGATGAACATCTGCAAAAAGGAGTGAACATTTTGACTAGCTACATT AATGAACTTCGAACCTTCATGATAAAGTTTCCTTGGAAGCTAACAGATGCTATAGATGAATATGATGTACATGAAAATGTCCCCAAAGTA AAGGAGAGCAATATATGGAAGAAACTCAGCTTTGAGGAAGTTATTGCCAGCGCCATTTTAAACAACAAAATACCAGAGGCACAGACTTTC TTCAGGATTGATAGTCATTCTGCTCAAAAACTTGAGGAGCTTATTGGCATAGGCCTAAATTTGGTCTTTGACAATTTAAAAAAGAACAAT ATAAAGGAAGCCTCTGAACTTTTGAAGAATATGGGGTTTGATGTAAAAGGCCAATTGCTCAAGATCTGCTTCTATACAACTAATAAAAAT ATACGTGACTTTTTGGTTGAAATTTTAAAAGAAAAAAATTATTTTTCTGAAAAAGAGAAAAGAACTATAGACTTCGTGCATCAAGTTGAG AAGCTTTATTTGGGACATTTCCAAGAAAATATGCAAATCCAGTCATTTCCCAGGTACTGGATAAAGGAACAAGATTTTTTCAAGCACAAG TCTGTTTTGGACTCATTCCTGAAATATGATTGTAAAGATGAATTTAACAAACAGGACCATAGAATTGTGTTAAATTGGGCTCTGTGGTGG GATCAACTAACACAAGAATCCATCCTTCTCCCCAGGATAAGTCCAGAAGAATACAAATCATATTCCCCTGAAGCCCTCTGGAGATACCTC ACAGCTCGCCATGATTGGTTAAACATTATCTTATGGATTGGAGAATTTCAAACCCAGCATAGTTATGCTTCACTTCAGCAGAACAAATGG CCCCTTCTGACTGTTGATGTTATTAACCAGAATACTTCCTGTAACAACTACATGAGGAATGAAATTTTAGATAAGCTGGCCAGGAATGGG GTTTTTTTGGCATCTGAACTGGAAGACTTTGAATGCTTCCTCCTAAGACTGAGCCGTATTGGAGGTGTAATACAGGATACCCTCCCTGTT CAAAACTACAAGACCAAAGAAGGTTGGGATTTCCATTCTCAATTCATTCTCTATTGTTTGGAGCACAGTCTGCAGCATCTTCTTTATGTC TACCTTGACTGTTACAAACTTAGTCCTGAAAATTGTCCCTTTTTGGAAAAAAAAGAGTTACATGAAGCACACCCTTGGTTTGAATTTTTA GTTCAGTGTCGACAAGTTGCCAGTAACTTAACAGATCCCAAACTGATCTTCCAGGCTAGCCTTGCAAATGCTCAGATTTTGATTCCCACC AATCAGGCCAGTGTAAGCAGTATGCTATTGGAAGGACATACCCTCCTGGCCCTTGCTACTACAATGTATTCTCCTGGGGGTGTCAGTCAG GTTGTTCAGAATGAAGAAAATGAAAACTGTTTGAAGAAAGTGGATCCCCAGCTATTGAAGATGGCATTAACTCCTTACCCCAAGCTAAAA ACTGCTCTCTTCCCACAGTGCACTCCTCCTAGTGTCCTGCCATCTGATATTACAATCTACCACCTTATTCAGTCATTATCACCCTTTGAT CCTAGCAGATTGTTTGGCTGGCAGTCTGCTAACACACTAGCTATAGGAGATGCATGGAGTCATCTCCCACATTTCTCTAGCCCTGACCTG GTTAATAAATATGCTATAGTGGAACGTCTGAATTTTGCTTATTATTTACATAATGGGCGGCCATCATTTGCATTTGGTACTTTTCTGGTC CAGGAATTAATCAAGAGCAAGACTCCCAAGCAGCTGATCCAGCAAGTAGGCAATGAAGCCTATGTTATAGGGCTCTCCTCCTTCCACATA CCTTCAATAGGAGCTGCATGTGTTTGTTTCTTAGAATTGCTTGGCCTTGACAGCCTCAAGCTCAGAGTTGATATGAAAGTGGCCAATATA ATTTTGAGCTACAAGTGCAGAAATGAAGATGCTCAGTACAGCTTTATCAGAGAGTCTGTAGCCGAAAAACTATCTAAACTAGCTGATGGT GAAAAGACAACCACAGAAGAATTGCTTGTTCTCTTAGAAGAAGGTACATGGAACAGCATTCAGCAACAGGAAATAAAGAGGTTATCCAGT GAATCTAGCAGCCAATGGGCATTAGTGGTGCAGTTCTGCAGGCTACACAATATGAAACTAAGCATATCTTACCTTAGAGAATGTGCCAAA GCAAATGATTGGCTGCAGTTCATTATTCACAGCCAACTCCACAACTACCACCCAGCAGAGGTGAAATCCCTTATCCAGTACTTCAGCCCA GTCATTCAAGACCACTTAAGGCTGGCTTTTGAGAACTTGCCCTCAGTGCCCACCTCCAAAATGGACAGCGATCAAGTCTGCAATAAGTGC CCCCAGGAACTTCAAGGAAGCAAACAAGAGATGACCGATTTATTTGAAATTCTGCTCCAATGCTCAGAGGAGCCAGACTCCTGGCACTGG CTTCTGGTTGAAGCAGTGAAACAACAGGCCCCTATCCTCAGTGTTCTGGCCTCATGTCTCCAGGGTGCCAGTGCCATTTCTTGTCTCTGT GTTTGGATCATCACTTCTGTGGAGGACAATGTTGCAACTGAAGCAATGGGACACATTCAGGACTCAACAGAGGACCATACCTGGAACCTT GAGGATCTTTCAGTCATCTGGAGAACATTATTAACAAGACAAAAGAGCAAAACTCTCATCAGAGGTTTCCAGCTTTTCTTTAAGGATTCC CCGTTACTACTGGTGATGGAGATGTATGAACTGTGTATGTTCTTCAGGAATTATAAAGAAGCTGAAGCTAAACTTCTGGAGTTTCAGAAG AGCCTTGAAACGCTTAACACAGCAGCCACAAAGGTCCACCCTGTCATCCCTGCCATGTGGCTGGAGGATCAGGTGTGTTTCCTTTTGAAG CTTATGCTACAGCAGTGTAAGACCCAGTATGAGCTGGGGAAGCTTTTACAGCTCTTTGTTGAAAGAGAGCATCTCTTCTCTGATGGTCCA GATGTGAAAAAGCTTTGCATCCTTTGCCAGATTTTGAAGGATACATCCATAGCCATTAATCATACAATTATTACCAGCTACAGCATTGAG AATCTTCAGCATGAATGTAGATCTATTTTGGAAAGACTGCAGACAGATGGACAATTCGCTTTGGCCAGGAGGGTAGCAGAATTAGCTGAG TTACCTGTGGACAACTTGGTTATTAAAGAGATAACACAGGAAATGCAGACCCTAAAACACATTGAACAGTGGTCACTAAAACAAGCAAGA ATTGACTTCTGGAAAAAATGCCATGAGAATTTTAAGAAAAATTCAATTTCAAGCAAAGCAGCTTCTTCCTTTTTCTCAACCCAGGCCCAT GTGGCATGTGAGCACCCAACTGGATGGAGCAGCATGGAGGAGCGCCATCTGCTGCTCACCTTGGCAGGGCACTGGCTTGCCCAGGAGGAC GTGGTGCCCTTGGATAAGCTGGAGGAGCTGGAGAAGCAGATCTGGCTGTGCCGCATCACCCAGCACACTCTTGGAAGAAATCAGGAGGAA ACAGAGCCCAGATTTTCTCGACAGATCTCAACTAGTGGTGAACTTTCCTTTGATAGTTTAGCCAGTGAGTTTTCCTTCTCCAAGTTGGCT GCTCTGAACACATCAAAATACTTAGAACTTAACAGCCTTCCATCCAAAGAGACATGCGAGAATAGATTGGATTGGAAAGAGCAGGAGTCA CTAAACTTTTTGATTGGGCGCCTACTGGATGATGGCTGTGTGCATGAAGCAAGTAGAGTATGCCGGTATTTTCATTTTTATAATCCAGAT GTCGCCTTGGTATTGCACTGCAGAGCACTGGCCTCAGGGGAAGCTAGTATGGAGGATCTGCACCCAGAGATCCATGCTCTCCTACAAAGT GCTGAGCTGCTTGAGGAAGAAGCACCCGACATTCCCCTAAGGAGAGTCCACAGCACTTCAAGTCTGGATAGTCAGAAGTTTGTGACAGTG CCCTCCAGTAATGAAGTGGTAACTAACCTGGAAGTGCTGACAAGCAAATGCCTCCATGGGAAGAACTACTGTCGACAGGTCCTCTGTCTG TATGATCTTGCCAAGGAGTTGGGCTGTTCCTACACAGATGTTGCTGCTCAGGATGGTGAAGCCATGCTCCGGAAAATCTTGGCCTCTCAG CAGCCTGACCGATGCAAACGAGCCCAGGCCTTCATCAGCACACAGGGCCTTAAGCCAGATACTGTGGCTGAACTCGTGGCAGAAGAGGTG ACACGGGAGCTGCTTACTTCATCACAGGGAACAGGACATAAGCAGATGTTCAACCCAACAGAGGAAAGCCAGACATTTCTTCAGCTGACC ACTCTGTGTCAAGACCGCACATTGGTAGGCATGAAGTTGTTGGATAAGATTTCCTCCGTTCCCCATGGGGAACTGTCTTGCACCACAGAG CTCCTGATCCTGGCCCATCATTGCTTCACCCTGACGTGCCACATGGAGGGCATCATCCGAGTCCTACAGGCCGCCCACATGCTCACAGAT AACCACCTGGCCCCCAGTGAGGAGTATGGGCTGGTGGTACGGCTCCTCACTGGCATTGGAAGGTACAACGAGATGACATACATATTTGAT TTGCTGCATAAAAAGCACTACTTTGAAGTGCTAATGAGGAAGAAGTTGGATCCGAGTGGTACCCTGAAAACAGCCCTGCTGGACTACATC AAACGCTGCCGTCCTGGAGACAGTGAAAAGCACAATATGATTGCCCTGTGCTTCAGCATGTGCCGGGAGATTGGCGAGAACCACGAGGCA GCTGCCCGCATCCAACTGAAATTGATTGAGTCTCAGCCCTGGGAGGACAGCCTCAAGGATGGGCACCAGCTGAAACAACTGCTGCTGAAG GCCCTGACTCTGATGTTGGATGCAGCAGAGAGTTATGCCAAGGACTCCTGTGTGCGACAGGCCCAGCACTGTCAGCGGCTCACCAAGTTG ATAACTCTGCAGATTCACTTTCTGAACACTGGCCAGAACACAATGCTCATCAACTTGGGCCGCCACAAGCTGATGGACTGTATTCTGGCC CTACCTCGGTTCTACCAGGCTTCTATTGTGGCTGAGGCCTACGATTTTGTTCCAGATTGGGCTGAAATTTTATACCAGCAAGTGATTCTT AAAGGAGACTTTAATTACTTGGAAGAATTTAAGCAGCAAAGGTTATTAAAGTCCAGTATATTTGAAGAGATTTCCAAAAAATATAAACAA CATCAGCCTACTGACATGGTCATGGAAAACCTGAAGAAATTACTCACATATTGTGAAGATGTTTACCTGTATTACAAGTTGGCATACGAA CACAAGTTTTATGAAATTGTAAATGTGCTTCTGAAGGACCCTCAGACAGGTTGCTGTCTAAAGGACATGCTAGCAGGTTAGATGATTTCA TAGGTGTCTGTTTTCTTGTACTGTTAGCAGATTCTGACAGATGTGATGAGAAGAAGAATGCATTGGAGATCTTTGCTAAAGTTGAACAAT CCCGGTACTGTACCATATCAGTCCTTTGTGGGTAGTAGGTAGCAAGTAAGAAACTTTTCAGGAGGAAATTCCTATTTAAAATAGATTGAT TTTAGATGATTGTTCATCCACACCATTTTATATAGATACTAGTATTAAGATCAAAAGCTTCCTCTTCCTCAGGACAGCTTCTACTTTAGA TGATCCAATAATGATTAAAGAATACCTGTACCTGCAGATTCCAGTTTCAAAGAAATTTAATTATTATTTACACAGTTAAGGAACAGGTGA >72634_72634_5_RBFA-SPG11_RBFA_chr18_77794653_ENST00000306735_SPG11_chr15_44952814_ENST00000261866_length(amino acids)=2453AA_BP=96 MPGVSLPPALRRRPAHTPPPSRQLSLRACARCLPARSGSRRRAMWAAAGGLWRSRAGLRALFRSRDAALFPGCERGLHCSAVSCKNWLKK FASKTNFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINK CVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFT SLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIK NSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFT WEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPI HALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNN QIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTDAIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRI DSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVKGQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLY LGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFNKQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTAR HDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNNYMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNY KTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLEKKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQA SVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDPQLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSR LFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYLHNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSI GAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFIRESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESS SQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNYHPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQE LQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVLASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDL SVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFRNYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLML QQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTSIAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPV DNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSISSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVP LDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELSFDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNF LIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEASMEDLHPEIHALLQSAELLEEEAPDIPLRRVHSTSSLDSQKFVTVPSS NEVVTNLEVLTSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAAQDGEAMLRKILASQQPDRCKRAQAFISTQGLKPDTVAELVAEEVTRE LLTSSQGTGHKQMFNPTEESQTFLQLTTLCQDRTLVGMKLLDKISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLQAAHMLTDNHL APSEEYGLVVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAAR IQLKLIESQPWEDSLKDGHQLKQLLLKALTLMLDAAESYAKDSCVRQAQHCQRLTKLITLQIHFLNTGQNTMLINLGRHKLMDCILALPR FYQASIVAEAYDFVPDWAEILYQQVILKGDFNYLEEFKQQRLLKSSIFEEISKKYKQHQPTDMVMENLKKLLTYCEDVYLYYKLAYEHKF -------------------------------------------------------------- >72634_72634_6_RBFA-SPG11_RBFA_chr18_77794653_ENST00000306735_SPG11_chr15_44952814_ENST00000427534_length(transcript)=6974nt_BP=296nt ACACGCCGCCTGCCAGGCGTGAGTCTTCCTCCCGCTCTGCGCCGTCGCCCCGCCCACACGCCGCCACCCTCGCGTCAGTTGTCGCTCCGC GCCTGCGCCCGTTGTCTCCCTGCTCGCTCCGGGTCCCGGCGCCGCGCCATGTGGGCTGCGGCGGGCGGGCTGTGGCGCTCCCGCGCGGGT CTCCGGGCCCTGTTCCGTAGCCGCGATGCTGCGCTATTTCCAGGCTGCGAGCGGGGACTTCACTGCTCTGCTGTCTCCTGCAAGAACTGG CTCAAGAAATTTGCCTCGAAAACCAACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTT GGTGAAAATTATGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCA TTGCAAAAGCTCATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTC ATCAACAAATGTGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCA CAGGCAGTGGACATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTT GTGGATGGTACATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCT TCATTTACTTCACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTG TATTTCAGGCAACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGAT CCTGTTAACTCTGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAA ACAATAAAGAACTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCAC AGTACAAGTGTGCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGT GATCCAGGAAGATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCA CTGTTTACTTGGGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACA AAGTGTATTCCTGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACT CAAGAAGAGTTTTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCA ATTCCCATACATGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAAT CCATCCTCAAAATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAAATGTGGAAGAGCTGATACCAGCATTG GATTTACTTTGCTCGGCAATTAGAGAAAGTTATTCTGAACCCCAAAGCAAACACTTTTCAGAACAATTGCTTAATCTTACACTGTCTTTC CTTAACAACCAAATAAAGGAGCTTTTCATTCACACTGAAGAACTAGATGAACATCTGCAAAAAGGAGTGAACATTTTGACTAGCTACATT AATGAACTTCGAACCTTCATGATAAAGTTTCCTTGGAAGCTAACAGATGCTATAGATGAATATGATGTACATGAAAATGTCCCCAAAGTA AAGGAGAGCAATATATGGAAGAAACTCAGCTTTGAGGAAGTTATTGCCAGCGCCATTTTAAACAACAAAATACCAGAGGCACAGACTTTC TTCAGGATTGATAGTCATTCTGCTCAAAAACTTGAGGAGCTTATTGGCATAGGCCTAAATTTGGTCTTTGACAATTTAAAAAAGAACAAT ATAAAGGAAGCCTCTGAACTTTTGAAGAATATGGGGTTTGATGTAAAAGGCCAATTGCTCAAGATCTGCTTCTATACAACTAATAAAAAT ATACGTGACTTTTTGGTTGAAATTTTAAAAGAAAAAAATTATTTTTCTGAAAAAGAGAAAAGAACTATAGACTTCGTGCATCAAGTTGAG AAGCTTTATTTGGGACATTTCCAAGAAAATATGCAAATCCAGTCATTTCCCAGGTACTGGATAAAGGAACAAGATTTTTTCAAGCACAAG TCTGTTTTGGACTCATTCCTGAAATATGATTGTAAAGATGAATTTAACAAACAGGACCATAGAATTGTGTTAAATTGGGCTCTGTGGTGG GATCAACTAACACAAGAATCCATCCTTCTCCCCAGGATAAGTCCAGAAGAATACAAATCATATTCCCCTGAAGCCCTCTGGAGATACCTC ACAGCTCGCCATGATTGGTTAAACATTATCTTATGGATTGGAGAATTTCAAACCCAGCATAGTTATGCTTCACTTCAGCAGAACAAATGG CCCCTTCTGACTGTTGATGTTATTAACCAGAATACTTCCTGTAACAACTACATGAGGAATGAAATTTTAGATAAGCTGGCCAGGAATGGG GTTTTTTTGGCATCTGAACTGGAAGACTTTGAATGCTTCCTCCTAAGACTGAGCCGTATTGGAGGTGTAATACAGGATACCCTCCCTGTT CAAAACTACAAGACCAAAGAAGGTTGGGATTTCCATTCTCAATTCATTCTCTATTGTTTGGAGCACAGTCTGCAGCATCTTCTTTATGTC TACCTTGACTGTTACAAACTTAGTCCTGAAAATTGTCCCTTTTTGGAAAAAAAAGAGTTACATGAAGCACACCCTTGGTTTGAATTTTTA GTTCAGTGTCGACAAGTTGCCAGTAACTTAACAGATCCCAAACTGATCTTCCAGGCTAGCCTTGCAAATGCTCAGATTTTGATTCCCACC AATCAGGCCAGTGTAAGCAGTATGCTATTGGAAGGACATACCCTCCTGGCCCTTGCTACTACAATGTATTCTCCTGGGGGTGTCAGTCAG GTTGTTCAGAATGAAGAAAATGAAAACTGTTTGAAGAAAGTGGATCCCCAGCTATTGAAGATGGCATTAACTCCTTACCCCAAGCTAAAA ACTGCTCTCTTCCCACAGTGCACTCCTCCTAGTGTCCTGCCATCTGATATTACAATCTACCACCTTATTCAGTCATTATCACCCTTTGAT CCTAGCAGATTGTTTGGCTGGCAGTCTGCTAACACACTAGCTATAGGAGATGCATGGAGTCATCTCCCACATTTCTCTAGCCCTGACCTG GTTAATAAATATGCTATAGTGGAACGTCTGAATTTTGCTTATTATTTACATAATGGGCGGCCATCATTTGCATTTGGTACTTTTCTGGTC CAGGAATTAATCAAGAGCAAGACTCCCAAGCAGCTGATCCAGCAAGTAGGCAATGAAGCCTATGTTATAGGGCTCTCCTCCTTCCACATA CCTTCAATAGGAGCTGCATGTGTTTGTTTCTTAGAATTGCTTGGCCTTGACAGCCTCAAGCTCAGAGTTGATATGAAAGTGGCCAATATA ATTTTGAGCTACAAGTGCAGAAATGAAGATGCTCAGTACAGCTTTATCAGAGAGTCTGTAGCCGAAAAACTATCTAAACTAGCTGATGGT GAAAAGACAACCACAGAAGAATTGCTTGTTCTCTTAGAAGAAGGTACATGGAACAGCATTCAGCAACAGGAAATAAAGAGGTTATCCAGT GAATCTAGCAGCCAATGGGCATTAGTGGTGCAGTTCTGCAGGCTACACAATATGAAACTAAGCATATCTTACCTTAGAGAATGTGCCAAA GCAAATGATTGGCTGCAGTTCATTATTCACAGCCAACTCCACAACTACCACCCAGCAGAGGTGAAATCCCTTATCCAGTACTTCAGCCCA GTCATTCAAGACCACTTAAGGCTGGCTTTTGAGAACTTGCCCTCAGTGCCCACCTCCAAAATGGACAGCGATCAAGTCTGCAATAAGTGC CCCCAGGAACTTCAAGGAAGCAAACAAGAGATGACCGATTTATTTGAAATTCTGCTCCAATGCTCAGAGGAGCCAGACTCCTGGCACTGG CTTCTGGTTGAAGCAGTGAAACAACAGGCCCCTATCCTCAGTGTTCTGGCCTCATGTCTCCAGGGTGCCAGTGCCATTTCTTGTCTCTGT GTTTGGATCATCACTTCTGTGGAGGACAATGTTGCAACTGAAGCAATGGGACACATTCAGGACTCAACAGAGGACCATACCTGGAACCTT GAGGATCTTTCAGTCATCTGGAGAACATTATTAACAAGACAAAAGAGCAAAACTCTCATCAGAGGTTTCCAGCTTTTCTTTAAGGATTCC CCGTTACTACTGGTGATGGAGATGTATGAACTGTGTATGTTCTTCAGGAATTATAAAGAAGCTGAAGCTAAACTTCTGGAGTTTCAGAAG AGCCTTGAAACGCTTAACACAGCAGCCACAAAGGTCCACCCTGTCATCCCTGCCATGTGGCTGGAGGATCAGGTGTGTTTCCTTTTGAAG CTTATGCTACAGCAGTGTAAGACCCAGTATGAGCTGGGGAAGCTTTTACAGCTCTTTGTTGAAAGAGAGCATCTCTTCTCTGATGGTCCA GATGTGAAAAAGCTTTGCATCCTTTGCCAGATTTTGAAGGATACATCCATAGCCATTAATCATACAATTATTACCAGCTACAGCATTGAG AATCTTCAGCATGAATGTAGATCTATTTTGGAAAGACTGCAGACAGATGGACAATTCGCTTTGGCCAGGAGGGTAGCAGAATTAGCTGAG TTACCTGTGGACAACTTGGTTATTAAAGAGATAACACAGGAAATGCAGACCCTAAAACACATTGAACAGTGGTCACTAAAACAAGCAAGA ATTGACTTCTGGAAAAAATGCCATGAGAATTTTAAGAAAAATTCAATTTCAAGCAAAGCAGCTTCTTCCTTTTTCTCAACCCAGGCCCAT GTGGCATGTGAGCACCCAACTGGATGGAGCAGCATGGAGGAGCGCCATCTGCTGCTCACCTTGGCAGGGCACTGGCTTGCCCAGGAGGAC GTGGTGCCCTTGGATAAGCTGGAGGAGCTGGAGAAGCAGATCTGGCTGTGCCGCATCACCCAGCACACTCTTGGAAGAAATCAGGAGGAA ACAGAGCCCAGATTTTCTCGACAGATCTCAACTAGTGGTGAACTTTCCTTTGATAGTTTAGCCAGTGAGTTTTCCTTCTCCAAGTTGGCT GCTCTGAACACATCAAAATACTTAGAACTTAACAGCCTTCCATCCAAAGAGACATGCGAGAATAGATTGGATTGGAAAGAGCAGGAGTCA CTAAACTTTTTGATTGGGCGCCTACTGGATGATGGCTGTGTGCATGAAGCAAGTAGAGTATGCCGGTATTTTCATTTTTATAATCCAGAT GTCGCCTTGGTATTGCACTGCAGAGCACTGGCCTCAGGGGAAGCTAGTATGGAGGATCTGCACCCAGAGATCCATGCTCTCCTACAAAGT GCTGAGCTGCTTGAGGAAGAAGCACCCGACATTCCCCTAAGGAGAGTCCACAGCACTTCAAGTCTGGATAGTCAGAAGTTTGTGACAGTG CCCTCCAGTAATGAAGTGGTAACTAACCTGGAAGTGCTGACAAGCAAATGCCTCCATGGGAAGAACTACTGTCGACAGGTCCTCTGTCTG TATGATCTTGCCAAGGAGTTGGGCTGTTCCTACACAGATGTTGCTGCTCAGGATGGTGAAGCCATGCTCCGGAAAATCTTGGCCTCTCAG CAGCCTGACCGATGCAAACGAGCCCAGGCCTTCATCAGCACACAGGGCCTTAAGCCAGATACTGTGGCTGAACTCGTGGCAGAAGAGGTG ACACGGGAGCTGCTTACTTCATCACAGGGAACAGGACATAAGCAGATGTTCAACCCAACAGAGGAAAGCCAGACATTTCTTCAGCTGACC ACTCTGTGTCAAGACCGCACATTGGTAGGCATGAAGTTGTTGGATAAGATTTCCTCCGTTCCCCATGGGGAACTGTCTTGCACCACAGAG CTCCTGATCCTGGCCCATCATTGCTTCACCCTGACGTGCCACATGGAGGGCATCATCCGAGTCCTACAGGCCGCCCACATGCTCACAGAT AACCACCTGGCCCCCAGTGAGGAGTATGGGCTGGTGGTACGGCTCCTCACTGGCATTGGAAGGTACAACGAGATGACATACATATTTGAT TTGCTGCATAAAAAGCACTACTTTGAAGTGCTAATGAGGAAGAAGTTGGATCCGAGTGGTACCCTGAAAACAGCCCTGCTGGACTACATC AAACGCTGCCGTCCTGGAGACAGTGAAAAGCACAATATGATTGCCCTGTGCTTCAGCATGTGCCGGGAGATTGGCGAGAACCACGAGGCA GCTGCCCGCATCCAACTGAAATTGATTGAGTCTCAGCCCTGGGATATAAACAACATCAGCCTACTGACATGGTCATGGAAAACCTGAAGA AATTACTCACATATTGTGAAGATGTTTACCTGTATTACAAGTTGGCATACGAACACAAGTTTTATGAAATTGTAAATGTGCTTCTGAAGG >72634_72634_6_RBFA-SPG11_RBFA_chr18_77794653_ENST00000306735_SPG11_chr15_44952814_ENST00000427534_length(amino acids)=2275AA_BP=96 MPGVSLPPALRRRPAHTPPPSRQLSLRACARCLPARSGSRRRAMWAAAGGLWRSRAGLRALFRSRDAALFPGCERGLHCSAVSCKNWLKK FASKTNFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINK CVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFT SLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIK NSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFT WEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPI HALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNN QIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTDAIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRI DSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVKGQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLY LGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFNKQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTAR HDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNNYMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNY KTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLEKKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQA SVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDPQLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSR LFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYLHNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSI GAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFIRESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESS SQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNYHPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQE LQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVLASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDL SVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFRNYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLML QQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTSIAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPV DNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSISSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVP LDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELSFDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNF LIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEASMEDLHPEIHALLQSAELLEEEAPDIPLRRVHSTSSLDSQKFVTVPSS NEVVTNLEVLTSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAAQDGEAMLRKILASQQPDRCKRAQAFISTQGLKPDTVAELVAEEVTRE LLTSSQGTGHKQMFNPTEESQTFLQLTTLCQDRTLVGMKLLDKISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLQAAHMLTDNHL APSEEYGLVVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAAR -------------------------------------------------------------- >72634_72634_7_RBFA-SPG11_RBFA_chr18_77794653_ENST00000306735_SPG11_chr15_44952814_ENST00000535302_length(transcript)=7299nt_BP=296nt ACACGCCGCCTGCCAGGCGTGAGTCTTCCTCCCGCTCTGCGCCGTCGCCCCGCCCACACGCCGCCACCCTCGCGTCAGTTGTCGCTCCGC GCCTGCGCCCGTTGTCTCCCTGCTCGCTCCGGGTCCCGGCGCCGCGCCATGTGGGCTGCGGCGGGCGGGCTGTGGCGCTCCCGCGCGGGT CTCCGGGCCCTGTTCCGTAGCCGCGATGCTGCGCTATTTCCAGGCTGCGAGCGGGGACTTCACTGCTCTGCTGTCTCCTGCAAGAACTGG CTCAAGAAATTTGCCTCGAAAACCAACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTT GGTGAAAATTATGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCA TTGCAAAAGCTCATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTC ATCAACAAATGTGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCA CAGGCAGTGGACATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTT GTGGATGGTACATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCT TCATTTACTTCACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTG TATTTCAGGCAACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGAT CCTGTTAACTCTGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAA ACAATAAAGAACTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCAC AGTACAAGTGTGCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGT GATCCAGGAAGATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCA CTGTTTACTTGGGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACA AAGTGTATTCCTGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACT CAAGAAGAGTTTTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCA ATTCCCATACATGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAAT CCATCCTCAAAATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAAATGTGGAAGAGCTGATACCAGCATTG GATTTACTTTGCTCGGCAATTAGAGAAAGTTATTCTGAACCCCAAAGCAAACACTTTTCAGAACAATTGCTTAATCTTACACTGTCTTTC CTTAACAACCAAATAAAGGAGCTTTTCATTCACACTGAAGAACTAGATGAACATCTGCAAAAAGGAGTGAACATTTTGACTAGCTACATT AATGAACTTCGAACCTTCATGATAAAGTTTCCTTGGAAGCTAACAGATGCTATAGATGAATATGATGTACATGAAAATGTCCCCAAAGTA AAGGAGAGCAATATATGGAAGAAACTCAGCTTTGAGGAAGTTATTGCCAGCGCCATTTTAAACAACAAAATACCAGAGGCACAGACTTTC TTCAGGATTGATAGTCATTCTGCTCAAAAACTTGAGGAGCTTATTGGCATAGGCCTAAATTTGGTCTTTGACAATTTAAAAAAGAACAAT ATAAAGGAAGCCTCTGAACTTTTGAAGAATATGGGGTTTGATGTAAAAGGCCAATTGCTCAAGATCTGCTTCTATACAACTAATAAAAAT ATACGTGACTTTTTGGTTGAAATTTTAAAAGAAAAAAATTATTTTTCTGAAAAAGAGAAAAGAACTATAGACTTCGTGCATCAAGTTGAG AAGCTTTATTTGGGACATTTCCAAGAAAATATGCAAATCCAGTCATTTCCCAGGTACTGGATAAAGGAACAAGATTTTTTCAAGCACAAG TCTGTTTTGGACTCATTCCTGAAATATGATTGTAAAGATGAATTTAACAAACAGGACCATAGAATTGTGTTAAATTGGGCTCTGTGGTGG GATCAACTAACACAAGAATCCATCCTTCTCCCCAGGATAAGTCCAGAAGAATACAAATCATATTCCCCTGAAGCCCTCTGGAGATACCTC ACAGCTCGCCATGATTGGTTAAACATTATCTTATGGATTGGAGAATTTCAAACCCAGCATAGTTATGCTTCACTTCAGCAGAACAAATGG CCCCTTCTGACTGTTGATGTTATTAACCAGAATACTTCCTGTAACAACTACATGAGGAATGAAATTTTAGATAAGCTGGCCAGGAATGGG GTTTTTTTGGCATCTGAACTGGAAGACTTTGAATGCTTCCTCCTAAGACTGAGCCGTATTGGAGGTGTAATACAGGATACCCTCCCTGTT CAAAACTACAAGACCAAAGAAGGTTGGGATTTCCATTCTCAATTCATTCTCTATTGTTTGGAGCACAGTCTGCAGCATCTTCTTTATGTC TACCTTGACTGTTACAAACTTAGTCCTGAAAATTGTCCCTTTTTGGAAAAAAAAGAGTTACATGAAGCACACCCTTGGTTTGAATTTTTA GTTCAGTGTCGACAAGTTGCCAGTAACTTAACAGATCCCAAACTGATCTTCCAGGCTAGCCTTGCAAATGCTCAGATTTTGATTCCCACC AATCAGGCCAGTGTAAGCAGTATGCTATTGGAAGGACATACCCTCCTGGCCCTTGCTACTACAATGTATTCTCCTGGGGGTGTCAGTCAG GTTGTTCAGAATGAAGAAAATGAAAACTGTTTGAAGAAAGTGGATCCCCAGCTATTGAAGATGGCATTAACTCCTTACCCCAAGCTAAAA ACTGCTCTCTTCCCACAGTGCACTCCTCCTAGTGTCCTGCCATCTGATATTACAATCTACCACCTTATTCAGTCATTATCACCCTTTGAT CCTAGCAGATTGTTTGGCTGGCAGTCTGCTAACACACTAGCTATAGGAGATGCATGGAGTCATCTCCCACATTTCTCTAGCCCTGACCTG GTTAATAAATATGCTATAGTGGAACGTCTGAATTTTGCTTATTATTTACATAATGGGCGGCCATCATTTGCATTTGGTACTTTTCTGGTC CAGGAATTAATCAAGAGCAAGACTCCCAAGCAGCTGATCCAGCAAGTAGGCAATGAAGCCTATGTTATAGGGCTCTCCTCCTTCCACATA CCTTCAATAGGAGCTGCATGTGTTTGTTTCTTAGAATTGCTTGGCCTTGACAGCCTCAAGCTCAGAGTTGATATGAAAGTGGCCAATATA ATTTTGAGCTACAAGTGCAGAAATGAAGATGCTCAGTACAGCTTTATCAGAGAGTCTGTAGCCGAAAAACTATCTAAACTAGCTGATGGT GAAAAGACAACCACAGAAGAATTGCTTGTTCTCTTAGAAGAAGGTACATGGAACAGCATTCAGCAACAGGAAATAAAGAGGTTATCCAGT GAATCTAGCAGCCAATGGGCATTAGTGGTGCAGTTCTGCAGGCTACACAATATGAAACTAAGCATATCTTACCTTAGAGAATGTGCCAAA GCAAATGATTGGCTGCAGTTCATTATTCACAGCCAACTCCACAACTACCACCCAGCAGAGGTGAAATCCCTTATCCAGTACTTCAGCCCA GTCATTCAAGACCACTTAAGGCTGGCTTTTGAGAACTTGCCCTCAGTGCCCACCTCCAAAATGGACAGCGATCAAGTCTGCAATAAGTGC CCCCAGGAACTTCAAGGAAGCAAACAAGAGATGACCGATTTATTTGAAATTCTGCTCCAATGCTCAGAGGAGCCAGACTCCTGGCACTGG CTTCTGGTTGAAGCAGTGAAACAACAGGCCCCTATCCTCAGTGTTCTGGCCTCATGTCTCCAGGGTGCCAGTGCCATTTCTTGTCTCTGT GTTTGGATCATCACTTCTGTGGAGGACAATGTTGCAACTGAAGCAATGGGACACATTCAGGACTCAACAGAGGACCATACCTGGAACCTT GAGGATCTTTCAGTCATCTGGAGAACATTATTAACAAGACAAAAGAGCAAAACTCTCATCAGAGGTTTCCAGCTTTTCTTTAAGGATTCC CCGTTACTACTGGTGATGGAGATGTATGAACTGTGTATGTTCTTCAGGAATTATAAAGAAGCTGAAGCTAAACTTCTGGAGTTTCAGAAG AGCCTTGAAACGCTTAACACAGCAGCCACAAAGGTCCACCCTGTCATCCCTGCCATGTGGCTGGAGGATCAGGTGTGTTTCCTTTTGAAG CTTATGCTACAGCAGTGTAAGACCCAGTATGAGCTGGGGAAGCTTTTACAGCTCTTTGTTGAAAGAGAGCATCTCTTCTCTGATGGTCCA GATGTGAAAAAGCTTTGCATCCTTTGCCAGATTTTGAAGGATACATCCATAGCCATTAATCATACAATTATTACCAGCTACAGCATTGAG AATCTTCAGCATGAATGTAGATCTATTTTGGAAAGACTGCAGACAGATGGACAATTCGCTTTGGCCAGGAGGGTAGCAGAATTAGCTGAG TTACCTGTGGACAACTTGGTTATTAAAGAGATAACACAGGAAATGCAGACCCTAAAACACATTGAACAGTGGTCACTAAAACAAGCAAGA ATTGACTTCTGGAAAAAATGCCATGAGAATTTTAAGAAAAATTCAATTTCAAGCAAAGCAGCTTCTTCCTTTTTCTCAACCCAGGCCCAT GTGGCATGTGAGCACCCAACTGGATGGAGCAGCATGGAGGAGCGCCATCTGCTGCTCACCTTGGCAGGGCACTGGCTTGCCCAGGAGGAC GTGGTGCCCTTGGATAAGCTGGAGGAGCTGGAGAAGCAGATCTGGCTGTGCCGCATCACCCAGCACACTCTTGGAAGAAATCAGGAGGAA ACAGAGCCCAGATTTTCTCGACAGATCTCAACTAGTGGTGAACTTTCCTTTGATAGTTTAGCCAGTGAGTTTTCCTTCTCCAAGTTGGCT GCTCTGAACACATCAAAATACTTAGAACTTAACAGCCTTCCATCCAAAGAGACATGCGAGAATAGATTGGATTGGAAAGAGCAGGAGTCA CTAAACTTTTTGATTGGGCGCCTACTGGATGATGGCTGTGTGCATGAAGCAAGTAGAGTATGCCGGTATTTTCATTTTTATAATCCAGAT GTCGCCTTGGTATTGCACTGCAGAGCACTGGCCTCAGGGGAAGCTAGTATGGAGGATCTGCACCCAGAGATCCATGCTCTCCTACAAAGT GCTGAGCTGCTTGAGGAAGAAGCACCCGACATTCCCCTAAGGAGAGTCCACAGCAGACATAAGCAGATGTTCAACCCAACAGAGGAAAGC CAGACATTTCTTCAGCTGACCACTCTGTGTCAAGACCGCACATTGGTAGGCATGAAGTTGTTGGATAAGATTTCCTCCGTTCCCCATGGG GAACTGTCTTGCACCACAGAGCTCCTGATCCTGGCCCATCATTGCTTCACCCTGACGTGCCACATGGAGGGCATCATCCGAGTCCTACAG GCCGCCCACATGCTCACAGATAACCACCTGGCCCCCAGTGAGGAGTATGGGCTGGTGGTACGGCTCCTCACTGGCATTGGAAGGTACAAC GAGATGACATACATATTTGATTTGCTGCATAAAAAGCACTACTTTGAAGTGCTAATGAGGAAGAAGTTGGATCCGAGTGGTACCCTGAAA ACAGCCCTGCTGGACTACATCAAACGCTGCCGTCCTGGAGACAGTGAAAAGCACAATATGATTGCCCTGTGCTTCAGCATGTGCCGGGAG ATTGGCGAGAACCACGAGGCAGCTGCCCGCATCCAACTGAAATTGATTGAGTCTCAGCCCTGGGAGGACAGCCTCAAGGATGGGCACCAG CTGAAACAACTGCTGCTGAAGGCCCTGACTCTGATGTTGGATGCAGCAGAGAGTTATGCCAAGGACTCCTGTGTGCGACAGGCCCAGCAC TGTCAGCGGCTCACCAAGTTGATAACTCTGCAGATTCACTTTCTGAACACTGGCCAGAACACAATGCTCATCAACTTGGGCCGCCACAAG CTGATGGACTGTATTCTGGCCCTACCTCGGTTCTACCAGGCTTCTATTGTGGCTGAGGCCTACGATTTTGTTCCAGATTGGGCTGAAATT TTATACCAGCAAGTGATTCTTAAAGGAGACTTTAATTACTTGGAAGAATTTAAGCAGCAAAGGTTATTAAAGTCCAGTATATTTGAAGAG ATTTCCAAAAAATATAAACAACATCAGCCTACTGACATGGTCATGGAAAACCTGAAGAAATTACTCACATATTGTGAAGATGTTTACCTG TATTACAAGTTGGCATACGAACACAAGTTTTATGAAATTGTAAATGTGCTTCTGAAGGACCCTCAGACAGGTTGCTGTCTAAAGGACATG CTAGCAGGTTAGATGATTTCATAGGTGTCTGTTTTCTTGTACTGTTAGCAGATTCTGACAGATGTGATGAGAAGAAGAATGCATTGGAGA TCTTTGCTAAAGTTGAACAATCCCGGTACTGTACCATATCAGTCCTTTGTGGGTAGTAGGTAGCAAGTAAGAAACTTTTCAGGAGGAAAT TCCTATTTAAAATAGATTGATTTTAGATGATTGTTCATCCACACCATTTTATATAGATACTAGTATTAAGATCAAAAGCTTCCTCTTCCT >72634_72634_7_RBFA-SPG11_RBFA_chr18_77794653_ENST00000306735_SPG11_chr15_44952814_ENST00000535302_length(amino acids)=2340AA_BP=96 MPGVSLPPALRRRPAHTPPPSRQLSLRACARCLPARSGSRRRAMWAAAGGLWRSRAGLRALFRSRDAALFPGCERGLHCSAVSCKNWLKK FASKTNFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINK CVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFT SLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIK NSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFT WEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPI HALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNN QIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTDAIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRI DSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVKGQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLY LGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFNKQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTAR HDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNNYMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNY KTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLEKKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQA SVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDPQLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSR LFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYLHNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSI GAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFIRESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESS SQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNYHPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQE LQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVLASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDL SVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFRNYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLML QQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTSIAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPV DNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSISSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVP LDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELSFDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNF LIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEASMEDLHPEIHALLQSAELLEEEAPDIPLRRVHSRHKQMFNPTEESQTF LQLTTLCQDRTLVGMKLLDKISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLQAAHMLTDNHLAPSEEYGLVVRLLTGIGRYNEMT YIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAARIQLKLIESQPWEDSLKDGHQLKQ LLLKALTLMLDAAESYAKDSCVRQAQHCQRLTKLITLQIHFLNTGQNTMLINLGRHKLMDCILALPRFYQASIVAEAYDFVPDWAEILYQ QVILKGDFNYLEEFKQQRLLKSSIFEEISKKYKQHQPTDMVMENLKKLLTYCEDVYLYYKLAYEHKFYEIVNVLLKDPQTGCCLKDMLAG -------------------------------------------------------------- >72634_72634_8_RBFA-SPG11_RBFA_chr18_77794653_ENST00000306735_SPG11_chr15_44952814_ENST00000558319_length(transcript)=6434nt_BP=296nt ACACGCCGCCTGCCAGGCGTGAGTCTTCCTCCCGCTCTGCGCCGTCGCCCCGCCCACACGCCGCCACCCTCGCGTCAGTTGTCGCTCCGC GCCTGCGCCCGTTGTCTCCCTGCTCGCTCCGGGTCCCGGCGCCGCGCCATGTGGGCTGCGGCGGGCGGGCTGTGGCGCTCCCGCGCGGGT CTCCGGGCCCTGTTCCGTAGCCGCGATGCTGCGCTATTTCCAGGCTGCGAGCGGGGACTTCACTGCTCTGCTGTCTCCTGCAAGAACTGG CTCAAGAAATTTGCCTCGAAAACCAACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTT GGTGAAAATTATGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCA TTGCAAAAGCTCATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTC ATCAACAAATGTGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCA CAGGCAGTGGACATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTT GTGGATGGTACATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCT TCATTTACTTCACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTG TATTTCAGGCAACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGAT CCTGTTAACTCTGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAA ACAATAAAGAACTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCAC AGTACAAGTGTGCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGT GATCCAGGAAGATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCA CTGTTTACTTGGGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACA AAGTGTATTCCTGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACT CAAGAAGAGTTTTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCA ATTCCCATACATGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAAT CCATCCTCAAAATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAAATGTGGAAGAGCTGATACCAGCATTG GATTTACTTTGCTCGGCAATTAGAGAAAGTTATTCTGAACCCCAAAGCAAACACTTTTCAGAACAATTGCTTAATCTTACACTGTCTTTC CTTAACAACCAAATAAAGGAGCTTTTCATTCACACTGAAGAACTAGATGAACATCTGCAAAAAGGAGTGAACATTTTGACTAGCTACATT AATGAACTTCGAACCTTCATGATAAAGTTTCCTTGGAAGCTAACAGATGCTATAGATGAATATGATGTACATGAAAATGTCCCCAAAGTA AAGGAGAGCAATATATGGAAGAAACTCAGCTTTGAGGAAGTTATTGCCAGCGCCATTTTAAACAACAAAATACCAGAGGCACAGACTTTC TTCAGGATTGATAGTCATTCTGCTCAAAAACTTGAGGAGCTTATTGGCATAGGCCTAAATTTGGTCTTTGACAATTTAAAAAAGAACAAT ATAAAGGAAGCCTCTGAACTTTTGAAGAATATGGGGTTTGATGTAAAAGGCCAATTGCTCAAGATCTGCTTCTATACAACTAATAAAAAT ATACGTGACTTTTTGGTTGAAATTTTAAAAGAAAAAAATTATTTTTCTGAAAAAGAGAAAAGAACTATAGACTTCGTGCATCAAGTTGAG AAGCTTTATTTGGGACATTTCCAAGAAAATATGCAAATCCAGTCATTTCCCAGGTACTGGATAAAGGAACAAGATTTTTTCAAGCACAAG TCTGTTTTGGACTCATTCCTGAAATATGATTGTAAAGATGAATTTAACAAACAGGACCATAGAATTGTGTTAAATTGGGCTCTGTGGTGG GATCAACTAACACAAGAATCCATCCTTCTCCCCAGGATAAGTCCAGAAGAATACAAATCATATTCCCCTGAAGCCCTCTGGAGATACCTC ACAGCTCGCCATGATTGGTTAAACATTATCTTATGGATTGGAGAATTTCAAACCCAGCATAGTTATGCTTCACTTCAGCAGAACAAATGG CCCCTTCTGACTGTTGATGTTATTAACCAGAATACTTCCTGTAACAACTACATGAGGAATGAAATTTTAGATAAGCTGGCCAGGAATGGG GTTTTTTTGGCATCTGAACTGGAAGACTTTGAATGCTTCCTCCTAAGACTGAGCCGTATTGGAGGTGTAATACAGGATACCCTCCCTGTT CAAAACTACAAGACCAAAGAAGGTTGGGATTTCCATTCTCAATTCATTCTCTATTGTTTGGAGCACAGTCTGCAGCATCTTCTTTATGTC TACCTTGACTGTTACAAACTTAGTCCTGAAAATTGTCCCTTTTTGGAAAAAAAAGAGTTACATGAAGCACACCCTTGGTTTGAATTTTTA GTTCAGTGTCGACAAGTTGCCAGTAACTTAACAGATCCCAAACTGATCTTCCAGGCTAGCCTTGCAAATGCTCAGATTTTGATTCCCACC AATCAGGCCAGTGTAAGCAGTATGCTATTGGAAGGACATACCCTCCTGGCCCTTGCTACTACAATGTATTCTCCTGGGGGTGTCAGTCAG GTTGTTCAGAATGAAGAAAATGAAAACTGTTTGAAGAAAGTGGATCCCCAGCTATTGAAGATGGCATTAACTCCTTACCCCAAGCTAAAA ACTGCTCTCTTCCCACAGTGCACTCCTCCTAGTGTCCTGCCATCTGATATTACAATCTACCACCTTATTCAGTCATTATCACCCTTTGAT CCTAGCAGATTGTTTGGCTGGCAGTCTGCTAACACACTAGCTATAGGAGATGCATGGAGTCATCTCCCACATTTCTCTAGCCCTGACCTG GTTAATAAATATGCTATAGTGGAACGTCTGAATTTTGCTTATTATTTACATAATGGGCGGCCATCATTTGCATTTGGTACTTTTCTGGTC CAGGAATTAATCAAGAGCAAGACTCCCAAGCAGCTGATCCAGCAAGTAGGCAATGAAGCCTATGTTATAGGGCTCTCCTCCTTCCACATA CCTTCAATAGGAGCTGCATGTGTTTGTTTCTTAGAATTGCTTGGCCTTGACAGCCTCAAGCTCAGAGTTGATATGAAAGTGGCCAATATA ATTTTGAGCTACAAGTGCAGAAATGAAGATGCTCAGTACAGCTTTATCAGAGAGTCTGTAGCCGAAAAACTATCTAAACTAGCTGATGGT GAAAAGACAACCACAGAAGAATTGCTTGTTCTCTTAGAAGAAGGTACATGGAACAGCATTCAGCAACAGGAAATAAAGAGGTTATCCAGT GAATCTAGCAGCCAATGGGCATTAGTGGTGCAGTTCTGCAGGCTACACAATATGAAACTAAGCATATCTTACCTTAGAGAATGTGCCAAA GCAAATGATTGGCTGCAGTTCATTATTCACAGCCAACTCCACAACTACCACCCAGCAGAGGTGAAATCCCTTATCCAGTACTTCAGCCCA GTCATTCAAGACCACTTAAGGCTGGCTTTTGAGAACTTGCCCTCAGTGCCCACCTCCAAAATGGACAGCGATCAAGTCTGCAATAAGTGC CCCCAGGAACTTCAAGGAAGCAAACAAGAGATGACCGATTTATTTGAAATTCTGCTCCAATGCTCAGAGGAGCCAGACTCCTGGCACTGG CTTCTGGTTGAAGCAGTGAAACAACAGGCCCCTATCCTCAGTGTTCTGGCCTCATGTCTCCAGGGTGCCAGTGCCATTTCTTGTCTCTGT GTTTGGATCATCACTTCTGTGGAGGACAATGTTGCAACTGAAGCAATGGGACACATTCAGGACTCAACAGAGGACCATACCTGGAACCTT GAGGATCTTTCAGTCATCTGGAGAACATTATTAACAAGACAAAAGAGCAAAACTCTCATCAGAGGTTTCCAGCTTTTCTTTAAGGATTCC CCGTTACTACTGGTGATGGAGATGTATGAACTGTGTATGTTCTTCAGGAATTATAAAGAAGCTGAAGCTAAACTTCTGGAGTTTCAGAAG AGCCTTGAAACGCTTAACACAGCAGCCACAAAGGTCCACCCTGTCATCCCTGCCATGTGGCTGGAGGATCAGGTGTGTTTCCTTTTGAAG CTTATGCTACAGCAGTGTAAGACCCAGTATGAGCTGGGGAAGCTTTTACAGCTCTTTGTTGAAAGAGAGCATCTCTTCTCTGATGGTCCA GATGTGAAAAAGCTTTGCATCCTTTGCCAGATTTTGAAGGATACATCCATAGCCATTAATCATACAATTATTACCAGCTACAGCATTGAG AATCTTCAGCATGAATGTAGATCTATTTTGGAAAGACTGCAGACAGATGGACAATTCGCTTTGGCCAGGAGGGTAGCAGAATTAGCTGAG TTACCTGTGGACAACTTGGTTATTAAAGAGATAACACAGGAAATGCAGACCCTAAAACACATTGAACAGTGGTCACTAAAACAAGCAAGA ATTGACTTCTGGAAAAAATGCCATGAGAATTTTAAGAAAAATTCAATTTCAAGCAAAGCAGCTTCTTCCTTTTTCTCAACCCAGGCCCAT GTGGCATGTGAGCACCCAACTGGATGGAGCAGCATGGAGGAGCGCCATCTGCTGCTCACCTTGGCAGGGCACTGGCTTGCCCAGGAGGAC GTGGTGCCCTTGGATAAGCTGGAGGAGCTGGAGAAGCAGATCTGGCTGTGCCGCATCACCCAGCACACTCTTGGAAGAAATCAGGAGGAA ACAGAGCCCAGATTTTCTCGACAGATCTCAACTAGTGGTGAACTTTCCTTTGATAGTTTAGCCAGTGAGTTTTCCTTCTCCAAGTTGGCT GCTCTGAACACATCAAAATACTTAGAACTTAACAGCCTTCCATCCAAAGAGACATGCGAGAATAGATTGGATTGGAAAGAGCAGGAGTCA CTAAACTTTTTGATTGGGCGCCTACTGGATGATGGCTGTGTGCATGAAGCAAGTAGAGTATGCCGGTATTTTCATTTTTATAATCCAGAT GTCGCCTTGGTATTGCACTGCAGAGCACTGGCCTCAGGGGAAGCTAGTATGGAGGATCTGCACCCAGAGATCCATGCTCTCCTACAAAGT GCTGAGCTGCTTGAGGAAGAAGCACCCGACATTCCCCTAAGGAGAGTCCACAGCACTTCAAGTCTGGATAGTCAGAAGTTTGTGACAGTG CCCTCCAGTAATGAAGTGGTAACTAACCTGGAAGTGCTGACAAGCAAATGCCTCCATGGGAAGAACTACTGTCGACAGGTCCTCTGTCTG TATGATCTTGCCAAGGAGTTGGGCTGTTCCTACACAGATGTTGCTGCTCAGGATGGTGAAGCCATGCTCCGGAAAATCTTGGCCTCTCAG CAGCCTGACCGATGCAAACGAGCCCAGGCCTTCATCAGCACACAGGGCCTTAAGCCAGATACTGTGGCTGAACTCGTGGCAGAAGAGGTG ACACGGGAGCTGCTTACTTCATCACAGGGAACAGGTGCCCTACCCCCCGGGGATTCCCAACCTCTCTGACAGCATTCTCTAGTTCCCAGT GTTAAGGATTTGGATGTTGTGCTTATATACATCCTGTATGTGGTTCTCTCAAGTTTCTGGATTGCAGTAATGTATTTTGTTTAAATAAAA >72634_72634_8_RBFA-SPG11_RBFA_chr18_77794653_ENST00000306735_SPG11_chr15_44952814_ENST00000558319_length(amino acids)=2089AA_BP=96 MPGVSLPPALRRRPAHTPPPSRQLSLRACARCLPARSGSRRRAMWAAAGGLWRSRAGLRALFRSRDAALFPGCERGLHCSAVSCKNWLKK FASKTNFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINK CVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFT SLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIK NSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFT WEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPI HALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNN QIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTDAIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRI DSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVKGQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLY LGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFNKQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTAR HDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNNYMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNY KTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLEKKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQA SVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDPQLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSR LFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYLHNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSI GAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFIRESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESS SQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNYHPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQE LQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVLASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDL SVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFRNYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLML QQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTSIAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPV DNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSISSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVP LDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELSFDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNF LIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEASMEDLHPEIHALLQSAELLEEEAPDIPLRRVHSTSSLDSQKFVTVPSS NEVVTNLEVLTSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAAQDGEAMLRKILASQQPDRCKRAQAFISTQGLKPDTVAELVAEEVTRE -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for RBFA-SPG11 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for RBFA-SPG11 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for RBFA-SPG11 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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