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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RBFOX2-CPT1A (FusionGDB2 ID:72671)

Fusion Gene Summary for RBFOX2-CPT1A

check button Fusion gene summary
Fusion gene informationFusion gene name: RBFOX2-CPT1A
Fusion gene ID: 72671
HgeneTgene
Gene symbol

RBFOX2

CPT1A

Gene ID

23543

1374

Gene nameRNA binding fox-1 homolog 2carnitine palmitoyltransferase 1A
SynonymsFOX2|Fox-2|HNRBP2|HRNBP2|RBM9|RTA|dJ106I20.3|fxhCPT1|CPT1-L|L-CPT1
Cytomap

22q12.3

11q13.3

Type of geneprotein-codingprotein-coding
DescriptionRNA binding protein fox-1 homolog 2RNA binding protein, fox-1 homolog 2RNA-binding motif protein 9fox-1 homolog Bfox-1 homologuehexaribonucleotide-binding protein 2repressor of tamoxifen transcriptional activitycarnitine O-palmitoyltransferase 1, liver isoformCPT ICPTI-Lcarnitine O-palmitoyltransferase I, liver isoformcarnitine palmitoyltransferase 1A (liver)carnitine palmitoyltransferase I, liver
Modification date2020032720200315
UniProtAcc.

P50416

Ensembl transtripts involved in fusion geneENST00000438146, ENST00000359369, 
ENST00000262829, ENST00000397303, 
ENST00000405409, ENST00000414461, 
ENST00000416721, ENST00000449924, 
ENST00000537756, ENST00000538994, 
ENST00000265641, ENST00000376618, 
ENST00000539743, ENST00000540367, 
Fusion gene scores* DoF score39 X 29 X 13=1470312 X 9 X 8=864
# samples 4815
** MAII scorelog2(48/14703*10)=-4.93693233652239
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/864*10)=-2.52606881166759
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RBFOX2 [Title/Abstract] AND CPT1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRBFOX2(36334895)-CPT1A(68571569), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRBFOX2

GO:0030520

intracellular estrogen receptor signaling pathway

11875103

HgeneRBFOX2

GO:0045892

negative regulation of transcription, DNA-templated

11875103

TgeneCPT1A

GO:0001676

long-chain fatty acid metabolic process

11350182

TgeneCPT1A

GO:0009437

carnitine metabolic process

11350182


check buttonFusion gene breakpoints across RBFOX2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CPT1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-EQ-8122-01ARBFOX2chr22

36334895

-CPT1Achr11

68571569

-


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Fusion Gene ORF analysis for RBFOX2-CPT1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000438146ENST00000537756RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
5CDS-intronENST00000438146ENST00000538994RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
5UTR-3CDSENST00000359369ENST00000265641RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
5UTR-3CDSENST00000359369ENST00000376618RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
5UTR-3CDSENST00000359369ENST00000539743RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
5UTR-3CDSENST00000359369ENST00000540367RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
5UTR-intronENST00000359369ENST00000537756RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
5UTR-intronENST00000359369ENST00000538994RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
In-frameENST00000438146ENST00000265641RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
In-frameENST00000438146ENST00000376618RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
In-frameENST00000438146ENST00000539743RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
In-frameENST00000438146ENST00000540367RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000262829ENST00000265641RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000262829ENST00000376618RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000262829ENST00000539743RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000262829ENST00000540367RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000397303ENST00000265641RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000397303ENST00000376618RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000397303ENST00000539743RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000397303ENST00000540367RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000405409ENST00000265641RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000405409ENST00000376618RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000405409ENST00000539743RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000405409ENST00000540367RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000414461ENST00000265641RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000414461ENST00000376618RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000414461ENST00000539743RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000414461ENST00000540367RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000416721ENST00000265641RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000416721ENST00000376618RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000416721ENST00000539743RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000416721ENST00000540367RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000449924ENST00000265641RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000449924ENST00000376618RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000449924ENST00000539743RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-3CDSENST00000449924ENST00000540367RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000262829ENST00000537756RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000262829ENST00000538994RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000397303ENST00000537756RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000397303ENST00000538994RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000405409ENST00000537756RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000405409ENST00000538994RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000414461ENST00000537756RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000414461ENST00000538994RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000416721ENST00000537756RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000416721ENST00000538994RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000449924ENST00000537756RBFOX2chr22

36334895

-CPT1Achr11

68571569

-
intron-intronENST00000449924ENST00000538994RBFOX2chr22

36334895

-CPT1Achr11

68571569

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000438146RBFOX2chr2236334895-ENST00000540367CPT1Achr1168571569-225123702054684
ENST00000438146RBFOX2chr2236334895-ENST00000376618CPT1Achr1168571569-224923702054684
ENST00000438146RBFOX2chr2236334895-ENST00000265641CPT1Achr1168571569-486123702105701
ENST00000438146RBFOX2chr2236334895-ENST00000539743CPT1Achr1168571569-213723702105701

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000438146ENST00000540367RBFOX2chr2236334895-CPT1Achr1168571569-0.0038867170.9961133
ENST00000438146ENST00000376618RBFOX2chr2236334895-CPT1Achr1168571569-0.0039825890.9960174
ENST00000438146ENST00000265641RBFOX2chr2236334895-CPT1Achr1168571569-0.0012106660.99878937
ENST00000438146ENST00000539743RBFOX2chr2236334895-CPT1Achr1168571569-0.004785780.9952142

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Fusion Genomic Features for RBFOX2-CPT1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RBFOX2-CPT1A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:36334895/chr11:68571569)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CPT1A

P50416

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion (PubMed:9691089, PubMed:11350182, PubMed:14517221). Plays an important role in hepatic triglyceride metabolism (By similarity). {ECO:0000250|UniProtKB:P32198, ECO:0000269|PubMed:11350182, ECO:0000269|PubMed:14517221, ECO:0000269|PubMed:9691089}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCPT1Achr22:36334895chr11:68571569ENST00000265641319555_567151774.0RegionCoenzyme A binding
TgeneCPT1Achr22:36334895chr11:68571569ENST00000376618319555_567151757.0RegionCoenzyme A binding
TgeneCPT1Achr22:36334895chr11:68571569ENST00000539743218555_567151774.0RegionCoenzyme A binding
TgeneCPT1Achr22:36334895chr11:68571569ENST00000540367218555_567151757.0RegionCoenzyme A binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000262829-112273_3770359.0Compositional biasNote=Ala-rich
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000405409-112273_3770368.0Compositional biasNote=Ala-rich
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000414461-112273_3770371.0Compositional biasNote=Ala-rich
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000416721-113273_3770377.0Compositional biasNote=Ala-rich
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000438146-214273_37779452.0Compositional biasNote=Ala-rich
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000449924-113273_3770381.0Compositional biasNote=Ala-rich
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000262829-112121_1970359.0DomainRRM
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000405409-112121_1970368.0DomainRRM
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000414461-112121_1970371.0DomainRRM
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000416721-113121_1970377.0DomainRRM
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000438146-214121_19779452.0DomainRRM
HgeneRBFOX2chr22:36334895chr11:68571569ENST00000449924-113121_1970381.0DomainRRM
TgeneCPT1Achr22:36334895chr11:68571569ENST00000265641319123_773151774.0Topological domainCytoplasmic
TgeneCPT1Achr22:36334895chr11:68571569ENST000002656413192_47151774.0Topological domainCytoplasmic
TgeneCPT1Achr22:36334895chr11:68571569ENST0000026564131974_102151774.0Topological domainMitochondrial intermembrane
TgeneCPT1Achr22:36334895chr11:68571569ENST00000376618319123_773151757.0Topological domainCytoplasmic
TgeneCPT1Achr22:36334895chr11:68571569ENST000003766183192_47151757.0Topological domainCytoplasmic
TgeneCPT1Achr22:36334895chr11:68571569ENST0000037661831974_102151757.0Topological domainMitochondrial intermembrane
TgeneCPT1Achr22:36334895chr11:68571569ENST00000539743218123_773151774.0Topological domainCytoplasmic
TgeneCPT1Achr22:36334895chr11:68571569ENST000005397432182_47151774.0Topological domainCytoplasmic
TgeneCPT1Achr22:36334895chr11:68571569ENST0000053974321874_102151774.0Topological domainMitochondrial intermembrane
TgeneCPT1Achr22:36334895chr11:68571569ENST00000540367218123_773151757.0Topological domainCytoplasmic
TgeneCPT1Achr22:36334895chr11:68571569ENST000005403672182_47151757.0Topological domainCytoplasmic
TgeneCPT1Achr22:36334895chr11:68571569ENST0000054036721874_102151757.0Topological domainMitochondrial intermembrane
TgeneCPT1Achr22:36334895chr11:68571569ENST00000265641319103_122151774.0TransmembraneHelical
TgeneCPT1Achr22:36334895chr11:68571569ENST0000026564131948_73151774.0TransmembraneHelical
TgeneCPT1Achr22:36334895chr11:68571569ENST00000376618319103_122151757.0TransmembraneHelical
TgeneCPT1Achr22:36334895chr11:68571569ENST0000037661831948_73151757.0TransmembraneHelical
TgeneCPT1Achr22:36334895chr11:68571569ENST00000539743218103_122151774.0TransmembraneHelical
TgeneCPT1Achr22:36334895chr11:68571569ENST0000053974321848_73151774.0TransmembraneHelical
TgeneCPT1Achr22:36334895chr11:68571569ENST00000540367218103_122151757.0TransmembraneHelical
TgeneCPT1Achr22:36334895chr11:68571569ENST0000054036721848_73151757.0TransmembraneHelical


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Fusion Gene Sequence for RBFOX2-CPT1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>72671_72671_1_RBFOX2-CPT1A_RBFOX2_chr22_36334895_ENST00000438146_CPT1A_chr11_68571569_ENST00000265641_length(transcript)=4861nt_BP=237nt
ATGGCGGAGGGCGCCCAGCCGCATCAGCCGCCTCAGCTCGGGCCCGGCGCCGCCGCCCGGGGCATGAAGCGGGAGTCGGAGCTGGAGCTG
CCGGTGCCCGGAGCGGGAGGAGACGGAGCCGATCCCGGCCTGAGCAAGCGGCCGCGCACTGAGGAGGCGGCGGCCGACGGTGGCGGCGGG
ATGCAGAACGAGCCTCTGACTCCAGGTTATCATGGATTCCCAGCGCGGGACAGCCAGGGTATGGTCAAGATCTTTTCAGGCCGAAAACCC
ATGTTGTACAGCTTCCAGACATCGCTGCCTCGCCTGCCGGTCCCGGCTGTCAAAGACACTGTGAACAGGTATCTACAGTCGGTGAGGCCT
CTTATGAAGGAAGAAGACTTCAAACGGATGACAGCACTTGCTCAAGATTTTGCTGTCGGTCTTGGACCAAGATTACAGTGGTATTTGAAG
TTAAAATCCTGGTGGGCTACAAATTACGTGAGCGACTGGTGGGAGGAGTACATCTACCTCCGAGGACGAGGGCCGCTCATGGTGAACAGC
AACTATTATGCCATGGATCTGCTGTATATCCTTCCAACTCACATTCAGGCAGCAAGAGCCGGCAACGCCATCCATGCCATCCTGCTTTAC
AGGCGCAAACTGGACCGGGAGGAAATCAAACCAATTCGTCTTTTGGGATCCACGATTCCACTCTGCTCCGCTCAGTGGGAGCGGATGTTT
AATACTTCCCGGATCCCAGGAGAGGAGACAGACACCATCCAGCACATGAGAGACAGCAAGCACATCGTCGTGTACCATCGAGGACGCTAC
TTCAAGGTCTGGCTCTACCATGATGGGCGGCTGCTGAAGCCCCGGGAGATGGAGCAGCAGATGCAGAGGATCCTGGACAATACCTCGGAG
CCTCAGCCCGGGGAGGCCAGGCTGGCAGCCCTCACCGCAGGAGACAGAGTTCCCTGGGCCAGGTGTCGTCAGGCCTATTTTGGACGTGGG
AAAAATAAGCAGTCTCTTGATGCTGTGGAGAAAGCAGCGTTCTTTGTGACGTTAGATGAAACTGAAGAAGGATACAGAAGTGAAGACCCG
GATACGTCAATGGACAGCTACGCCAAATCTCTACTACACGGCCGATGTTACGACAGGTGGTTTGACAAGTCGTTCACGTTTGTTGTCTTC
AAAAACGGGAAGATGGGCCTCAACGCTGAACACTCCTGGGCAGATGCGCCGATCGTGGCCCACCTTTGGGAGTACGTCATGTCCATTGAC
AGCCTCCAGCTGGGCTATGCGGAGGATGGGCACTGCAAAGGCGACATCAATCCGAACATTCCGTACCCCACCAGGCTGCAGTGGGACATC
CCGGGGGAATGTCAAGAGGTTATAGAGACCTCCCTGAACACCGCAAATCTTCTGGCAAACGACGTGGATTTCCATTCCTTCCCATTCGTA
GCCTTTGGTAAAGGAATCATCAAGAAATGTCGCACGAGCCCAGACGCCTTTGTGCAGCTGGCCCTCCAGCTGGCGCACTACAAGGACATG
GGCAAGTTTTGCCTCACATACGAGGCCTCCATGACCCGGCTCTTCCGAGAGGGGAGGACGGAGACCGTGCGCTCCTGCACCACTGAGTCA
TGCGACTTCGTGCGGGCCATGGTGGACCCGGCCCAGACGGTGGAACAGAGGCTGAAGTTGTTCAAGTTGGCGTCTGAGAAGCATCAGCAT
ATGTATCGCCTCGCCATGACCGGCTCTGGGATCGATCGTCACCTCTTCTGCCTTTACGTGGTGTCTAAATATCTCGCTGTGGAGTCCCCT
TTCCTTAAGGAAGTTTTATCTGAGCCTTGGAGATTATCAACAAGCCAGACCCCTCAGCAGCAAGTGGAGCTGTTTGACTTGGAGAATAAC
CCAGAGTACGTGTCCAGCGGAGGGGGCTTTGGACCGGTTGCTGATGACGGCTATGGTGTGTCGTACATCCTTGTGGGAGAGAACCTCATC
AATTTCCACATTTCTTCCAAGTTCTCTTGCCCTGAGACGGATTCTCATCGCTTTGGAAGGCACCTGAAAGAAGCAATGACTGACATCATC
ACTTTGTTTGGTCTCAGTTCTAATTCCAAAAAGTAATTCCACTGGAGCTGCTGGGAAGGAAAACGAGCTCTTCTGATGCAAACCAAATGA
AAAATAGGCATTAATCCTGACCTTAGCTCGGGATGAAACACTGCTCTTAAAAAAACTCAGTTTTCCTTCCAGAAAATGTGGGTGTTTTTT
TTTCCTAGAACAGTATCTCTCCCCTGTGAAGCATAACCCCACTACTTCCAGACTTGCCCTCCCTTGGGGGACATCTGATAAAGTCTCCCC
TGATGTCTCCGCATCGGCTTGGATTTATTAAGGGATGCAAATCTTGTTGAGTTAATGAAGGAATTAGTAGGGTTGTGGCTTCACACACAG
TGGAATGGAAATGGTGTGCTTTCTCAGTGGCAACCGAAGGCCTAGTGCTTAAGGGCATTTAGCATCATCCAAGCAGGGTAAACTTTTGTT
TTGTTAAAAGAAAAATGTGTTATTCAAGTTGGTGTCCCCAGTTGTAGCTAACACATCTGGAATGCACTAACCAAAATGCTGTGCTTTGGA
GACCTGCTTTTGTCACCGTGGGTAACCGTTCCCGTCTGGTCCAGTAGCCTGTGTTTGCCTCTCCACATTTGAAGCAAGCAGGATGCAAGG
TCTTCAGTTTTACTGACCTTGTATGTCTTCAAGTCTTCACAACCCAGTGCCTTAAAAATGAAAGGCCCTAAATGTAAGGGAGATGGAGAG
AAAGATTTATTTTGTAGAGTCTTTGGGTGGAATTGTGGGTATACTGTTCCCTTCACAATTGACTGAGTATGGATAACCGTACATAAGCAT
TTGCTACACCCCACCAGCCCCCTCCCCCTCAGAAACACCAGTTCCTTCCCAAGGGCAGCTGTGCCAGACTCCCCTCCCGGGACTGCCTTC
TTGTCATCATAAGCAACAAAAGAAATAACAGGCACATGTCATAAAAGGGGAGCAAGGGCCGTGATGGTCAGATAATTCACTCAAGAATAA
AACATGACACGTGCCTCAGGAGGATCTCTTTCCCAAAGTGACAGCAAGGAGGGCAGGGCATCGGCCACCAAGCGGGGACTAGCAAGTGAG
GAAGGGGAGGGCAGCCCACCGTGGTGAGGAGAGAGTGGCTCCACGACCCCAAGGGATGGCCTTCTCCTCCCACCCGGTGAGGGGAAAGAC
TCACCAGAGGGTGATGGAGACAGTATGCCGGCTCACCTTGGTGACCAGCCAAGATGTCTCAAGTGACAGTGCTAGGTGTTCACCCAGCCT
GTCCTTCAGATAGGAGTGCCTTCACGAAAGCGTCTCATGGACCACAAAGCAATTATGCACTGAGTCATCTTCAGTATTTAATGCAAAAAT
GAAGCATCATGGAATGAAATTCCCACTGTCTGTCATGACAAGCTTAGCTGTCCATTGTTTTAAATTGTGTATTTATTTTTTTGACCACTT
GGTTCTAGTTGGGCCTGACTCCTTCAGAGTGCTGCACCCCGATAGTACAACAGCGATGGCTGAACTGTTGGAGTCGATGGAAGGTGCTTG
CCGGAGAACACGTGCCTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAGTGGTGCAATCTCG
GCTCACTGCAGCATCTGCCTTGCAGGTTCAAGCGATTCTCCTGTCTCAGCCTCCCAAGTAGCTGGGATTACACGCCCAACACCATGCCCT
GCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCATCATATTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCTGCCTC
AGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCGCGGCCCACATGCATGTTTTATGTATGTATACTTCATGATGTAAAAAT
CCCACCTTTATGGGCCAAAGATTTTTTTTCTCCTGAAAGCAAGAAAAAATGAAAACAAAAGACAAAAAAAAAAAAAAAAGCGTCCAGGCG
CGGTGGCTCATGCGTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGGTCAGGAGATGGAGACCATCCTGGCTAACACG
GTGAAACCCCGTCTCTACTAAAAATTCAAAAAATGAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAG
GAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCGCTCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTC
TAAAAAAAAAAGCAAAAACAAACCAACAACAAAAGCCCCTGACTGTCCGTCAAGCAGGCAGCGGGGATGTAGCTCTCTCTGCCCTGGGCA
AGAATAGCACTTCCCGTTAAAAGCCAGCAGCCGGCGTCAGTCCCTATCAGAGCCAGCTAGATCATGCACTGTTGACCACTGAGCAATCTG
TGTTACACTAGAGTTCACAGGGCATTTTGAGTGTAGACGTGAGTGCTTAAACATATTTGGGTTTCTCTCTCAGGTTTTAAATGTTTCAAA
TGTAATTGTTGCTCATCAGTGCAGTTATCAATGCAATTTTATATTCCTTGAGGGGAGAAAGAGGGGTCTTATTGTACATGTCCAAGGGGG
GTGATAAGAGTATTATCTGTTTAATTTAATTGGAACAAACCATTGTCTTAACGCAGCCATGGTTTGAATTTGTTATCTTGGGCTGACCGG
TGCATGTAAATACAGTATGCTCTTTGGATGTAAATCTTAGAAATGCAGTGTGAATGTAGGTTATCATTAATAAAACATTAACCCCAGTCT

>72671_72671_1_RBFOX2-CPT1A_RBFOX2_chr22_36334895_ENST00000438146_CPT1A_chr11_68571569_ENST00000265641_length(amino acids)=701AA_BP=78
MAEGAQPHQPPQLGPGAAARGMKRESELELPVPGAGGDGADPGLSKRPRTEEAAADGGGGMQNEPLTPGYHGFPARDSQGMVKIFSGRKP
MLYSFQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNS
NYYAMDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRY
FKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDP
DTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDI
PGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTTES
CDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENN

--------------------------------------------------------------
>72671_72671_2_RBFOX2-CPT1A_RBFOX2_chr22_36334895_ENST00000438146_CPT1A_chr11_68571569_ENST00000376618_length(transcript)=2249nt_BP=237nt
ATGGCGGAGGGCGCCCAGCCGCATCAGCCGCCTCAGCTCGGGCCCGGCGCCGCCGCCCGGGGCATGAAGCGGGAGTCGGAGCTGGAGCTG
CCGGTGCCCGGAGCGGGAGGAGACGGAGCCGATCCCGGCCTGAGCAAGCGGCCGCGCACTGAGGAGGCGGCGGCCGACGGTGGCGGCGGG
ATGCAGAACGAGCCTCTGACTCCAGGTTATCATGGATTCCCAGCGCGGGACAGCCAGGGTATGGTCAAGATCTTTTCAGGCCGAAAACCC
ATGTTGTACAGCTTCCAGACATCGCTGCCTCGCCTGCCGGTCCCGGCTGTCAAAGACACTGTGAACAGGTATCTACAGTCGGTGAGGCCT
CTTATGAAGGAAGAAGACTTCAAACGGATGACAGCACTTGCTCAAGATTTTGCTGTCGGTCTTGGACCAAGATTACAGTGGTATTTGAAG
TTAAAATCCTGGTGGGCTACAAATTACGTGAGCGACTGGTGGGAGGAGTACATCTACCTCCGAGGACGAGGGCCGCTCATGGTGAACAGC
AACTATTATGCCATGGATCTGCTGTATATCCTTCCAACTCACATTCAGGCAGCAAGAGCCGGCAACGCCATCCATGCCATCCTGCTTTAC
AGGCGCAAACTGGACCGGGAGGAAATCAAACCAATTCGTCTTTTGGGATCCACGATTCCACTCTGCTCCGCTCAGTGGGAGCGGATGTTT
AATACTTCCCGGATCCCAGGAGAGGAGACAGACACCATCCAGCACATGAGAGACAGCAAGCACATCGTCGTGTACCATCGAGGACGCTAC
TTCAAGGTCTGGCTCTACCATGATGGGCGGCTGCTGAAGCCCCGGGAGATGGAGCAGCAGATGCAGAGGATCCTGGACAATACCTCGGAG
CCTCAGCCCGGGGAGGCCAGGCTGGCAGCCCTCACCGCAGGAGACAGAGTTCCCTGGGCCAGGTGTCGTCAGGCCTATTTTGGACGTGGG
AAAAATAAGCAGTCTCTTGATGCTGTGGAGAAAGCAGCGTTCTTTGTGACGTTAGATGAAACTGAAGAAGGATACAGAAGTGAAGACCCG
GATACGTCAATGGACAGCTACGCCAAATCTCTACTACACGGCCGATGTTACGACAGGTGGTTTGACAAGTCGTTCACGTTTGTTGTCTTC
AAAAACGGGAAGATGGGCCTCAACGCTGAACACTCCTGGGCAGATGCGCCGATCGTGGCCCACCTTTGGGAGTACGTCATGTCCATTGAC
AGCCTCCAGCTGGGCTATGCGGAGGATGGGCACTGCAAAGGCGACATCAATCCGAACATTCCGTACCCCACCAGGCTGCAGTGGGACATC
CCGGGGGAATGTCAAGAGGTTATAGAGACCTCCCTGAACACCGCAAATCTTCTGGCAAACGACGTGGATTTCCATTCCTTCCCATTCGTA
GCCTTTGGTAAAGGAATCATCAAGAAATGTCGCACGAGCCCAGACGCCTTTGTGCAGCTGGCCCTCCAGCTGGCGCACTACAAGGACATG
GGCAAGTTTTGCCTCACATACGAGGCCTCCATGACCCGGCTCTTCCGAGAGGGGAGGACGGAGACCGTGCGCTCCTGCACCACTGAGTCA
TGCGACTTCGTGCGGGCCATGGTGGACCCGGCCCAGACGGTGGAACAGAGGCTGAAGTTGTTCAAGTTGGCGTCTGAGAAGCATCAGCAT
ATGTATCGCCTCGCCATGACCGGCTCTGGGATCGATCGTCACCTCTTCTGCCTTTACGTGGTGTCTAAATATCTCGCTGTGGAGTCCCCT
TTCCTTAAGGAAGTTTTATCTGAGCCTTGGAGATTATCAACAAGCCAGACCCCTCAGCAGCAAGTGGAGCTGTTTGACTTGGAGAATAAC
CCAGAGTACGTGTCCAGCGGAGGGGGCTTTGGACCGGTTGCTGATGACGGCTATGGTGTGTCGTACATCCTTGTGGGAGAGAACCTCATC
AATTTCCACATTTCTTCCAAGTTCTCTTGCCCTGAGACGGGGATTATAAGTCAAGGACCAAGTTCAGATACTTGAGACAAAGTGGAAAGT
CTCAGCATATGGAAACAAGGCCTTGGAGGAGACCATGGACATCACCAAGTTCATGTGCTGGGCTGGAAAGAAAAGCCTGTTGATTTTCAC

>72671_72671_2_RBFOX2-CPT1A_RBFOX2_chr22_36334895_ENST00000438146_CPT1A_chr11_68571569_ENST00000376618_length(amino acids)=684AA_BP=78
MAEGAQPHQPPQLGPGAAARGMKRESELELPVPGAGGDGADPGLSKRPRTEEAAADGGGGMQNEPLTPGYHGFPARDSQGMVKIFSGRKP
MLYSFQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNS
NYYAMDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRY
FKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDP
DTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDI
PGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTTES
CDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENN

--------------------------------------------------------------
>72671_72671_3_RBFOX2-CPT1A_RBFOX2_chr22_36334895_ENST00000438146_CPT1A_chr11_68571569_ENST00000539743_length(transcript)=2137nt_BP=237nt
ATGGCGGAGGGCGCCCAGCCGCATCAGCCGCCTCAGCTCGGGCCCGGCGCCGCCGCCCGGGGCATGAAGCGGGAGTCGGAGCTGGAGCTG
CCGGTGCCCGGAGCGGGAGGAGACGGAGCCGATCCCGGCCTGAGCAAGCGGCCGCGCACTGAGGAGGCGGCGGCCGACGGTGGCGGCGGG
ATGCAGAACGAGCCTCTGACTCCAGGTTATCATGGATTCCCAGCGCGGGACAGCCAGGGTATGGTCAAGATCTTTTCAGGCCGAAAACCC
ATGTTGTACAGCTTCCAGACATCGCTGCCTCGCCTGCCGGTCCCGGCTGTCAAAGACACTGTGAACAGGTATCTACAGTCGGTGAGGCCT
CTTATGAAGGAAGAAGACTTCAAACGGATGACAGCACTTGCTCAAGATTTTGCTGTCGGTCTTGGACCAAGATTACAGTGGTATTTGAAG
TTAAAATCCTGGTGGGCTACAAATTACGTGAGCGACTGGTGGGAGGAGTACATCTACCTCCGAGGACGAGGGCCGCTCATGGTGAACAGC
AACTATTATGCCATGGATCTGCTGTATATCCTTCCAACTCACATTCAGGCAGCAAGAGCCGGCAACGCCATCCATGCCATCCTGCTTTAC
AGGCGCAAACTGGACCGGGAGGAAATCAAACCAATTCGTCTTTTGGGATCCACGATTCCACTCTGCTCCGCTCAGTGGGAGCGGATGTTT
AATACTTCCCGGATCCCAGGAGAGGAGACAGACACCATCCAGCACATGAGAGACAGCAAGCACATCGTCGTGTACCATCGAGGACGCTAC
TTCAAGGTCTGGCTCTACCATGATGGGCGGCTGCTGAAGCCCCGGGAGATGGAGCAGCAGATGCAGAGGATCCTGGACAATACCTCGGAG
CCTCAGCCCGGGGAGGCCAGGCTGGCAGCCCTCACCGCAGGAGACAGAGTTCCCTGGGCCAGGTGTCGTCAGGCCTATTTTGGACGTGGG
AAAAATAAGCAGTCTCTTGATGCTGTGGAGAAAGCAGCGTTCTTTGTGACGTTAGATGAAACTGAAGAAGGATACAGAAGTGAAGACCCG
GATACGTCAATGGACAGCTACGCCAAATCTCTACTACACGGCCGATGTTACGACAGGTGGTTTGACAAGTCGTTCACGTTTGTTGTCTTC
AAAAACGGGAAGATGGGCCTCAACGCTGAACACTCCTGGGCAGATGCGCCGATCGTGGCCCACCTTTGGGAGTACGTCATGTCCATTGAC
AGCCTCCAGCTGGGCTATGCGGAGGATGGGCACTGCAAAGGCGACATCAATCCGAACATTCCGTACCCCACCAGGCTGCAGTGGGACATC
CCGGGGGAATGTCAAGAGGTTATAGAGACCTCCCTGAACACCGCAAATCTTCTGGCAAACGACGTGGATTTCCATTCCTTCCCATTCGTA
GCCTTTGGTAAAGGAATCATCAAGAAATGTCGCACGAGCCCAGACGCCTTTGTGCAGCTGGCCCTCCAGCTGGCGCACTACAAGGACATG
GGCAAGTTTTGCCTCACATACGAGGCCTCCATGACCCGGCTCTTCCGAGAGGGGAGGACGGAGACCGTGCGCTCCTGCACCACTGAGTCA
TGCGACTTCGTGCGGGCCATGGTGGACCCGGCCCAGACGGTGGAACAGAGGCTGAAGTTGTTCAAGTTGGCGTCTGAGAAGCATCAGCAT
ATGTATCGCCTCGCCATGACCGGCTCTGGGATCGATCGTCACCTCTTCTGCCTTTACGTGGTGTCTAAATATCTCGCTGTGGAGTCCCCT
TTCCTTAAGGAAGTTTTATCTGAGCCTTGGAGATTATCAACAAGCCAGACCCCTCAGCAGCAAGTGGAGCTGTTTGACTTGGAGAATAAC
CCAGAGTACGTGTCCAGCGGAGGGGGCTTTGGACCGGTTGCTGATGACGGCTATGGTGTGTCGTACATCCTTGTGGGAGAGAACCTCATC
AATTTCCACATTTCTTCCAAGTTCTCTTGCCCTGAGACGGATTCTCATCGCTTTGGAAGGCACCTGAAAGAAGCAATGACTGACATCATC

>72671_72671_3_RBFOX2-CPT1A_RBFOX2_chr22_36334895_ENST00000438146_CPT1A_chr11_68571569_ENST00000539743_length(amino acids)=701AA_BP=78
MAEGAQPHQPPQLGPGAAARGMKRESELELPVPGAGGDGADPGLSKRPRTEEAAADGGGGMQNEPLTPGYHGFPARDSQGMVKIFSGRKP
MLYSFQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNS
NYYAMDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRY
FKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDP
DTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDI
PGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTTES
CDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENN

--------------------------------------------------------------
>72671_72671_4_RBFOX2-CPT1A_RBFOX2_chr22_36334895_ENST00000438146_CPT1A_chr11_68571569_ENST00000540367_length(transcript)=2251nt_BP=237nt
ATGGCGGAGGGCGCCCAGCCGCATCAGCCGCCTCAGCTCGGGCCCGGCGCCGCCGCCCGGGGCATGAAGCGGGAGTCGGAGCTGGAGCTG
CCGGTGCCCGGAGCGGGAGGAGACGGAGCCGATCCCGGCCTGAGCAAGCGGCCGCGCACTGAGGAGGCGGCGGCCGACGGTGGCGGCGGG
ATGCAGAACGAGCCTCTGACTCCAGGTTATCATGGATTCCCAGCGCGGGACAGCCAGGGTATGGTCAAGATCTTTTCAGGCCGAAAACCC
ATGTTGTACAGCTTCCAGACATCGCTGCCTCGCCTGCCGGTCCCGGCTGTCAAAGACACTGTGAACAGGTATCTACAGTCGGTGAGGCCT
CTTATGAAGGAAGAAGACTTCAAACGGATGACAGCACTTGCTCAAGATTTTGCTGTCGGTCTTGGACCAAGATTACAGTGGTATTTGAAG
TTAAAATCCTGGTGGGCTACAAATTACGTGAGCGACTGGTGGGAGGAGTACATCTACCTCCGAGGACGAGGGCCGCTCATGGTGAACAGC
AACTATTATGCCATGGATCTGCTGTATATCCTTCCAACTCACATTCAGGCAGCAAGAGCCGGCAACGCCATCCATGCCATCCTGCTTTAC
AGGCGCAAACTGGACCGGGAGGAAATCAAACCAATTCGTCTTTTGGGATCCACGATTCCACTCTGCTCCGCTCAGTGGGAGCGGATGTTT
AATACTTCCCGGATCCCAGGAGAGGAGACAGACACCATCCAGCACATGAGAGACAGCAAGCACATCGTCGTGTACCATCGAGGACGCTAC
TTCAAGGTCTGGCTCTACCATGATGGGCGGCTGCTGAAGCCCCGGGAGATGGAGCAGCAGATGCAGAGGATCCTGGACAATACCTCGGAG
CCTCAGCCCGGGGAGGCCAGGCTGGCAGCCCTCACCGCAGGAGACAGAGTTCCCTGGGCCAGGTGTCGTCAGGCCTATTTTGGACGTGGG
AAAAATAAGCAGTCTCTTGATGCTGTGGAGAAAGCAGCGTTCTTTGTGACGTTAGATGAAACTGAAGAAGGATACAGAAGTGAAGACCCG
GATACGTCAATGGACAGCTACGCCAAATCTCTACTACACGGCCGATGTTACGACAGGTGGTTTGACAAGTCGTTCACGTTTGTTGTCTTC
AAAAACGGGAAGATGGGCCTCAACGCTGAACACTCCTGGGCAGATGCGCCGATCGTGGCCCACCTTTGGGAGTACGTCATGTCCATTGAC
AGCCTCCAGCTGGGCTATGCGGAGGATGGGCACTGCAAAGGCGACATCAATCCGAACATTCCGTACCCCACCAGGCTGCAGTGGGACATC
CCGGGGGAATGTCAAGAGGTTATAGAGACCTCCCTGAACACCGCAAATCTTCTGGCAAACGACGTGGATTTCCATTCCTTCCCATTCGTA
GCCTTTGGTAAAGGAATCATCAAGAAATGTCGCACGAGCCCAGACGCCTTTGTGCAGCTGGCCCTCCAGCTGGCGCACTACAAGGACATG
GGCAAGTTTTGCCTCACATACGAGGCCTCCATGACCCGGCTCTTCCGAGAGGGGAGGACGGAGACCGTGCGCTCCTGCACCACTGAGTCA
TGCGACTTCGTGCGGGCCATGGTGGACCCGGCCCAGACGGTGGAACAGAGGCTGAAGTTGTTCAAGTTGGCGTCTGAGAAGCATCAGCAT
ATGTATCGCCTCGCCATGACCGGCTCTGGGATCGATCGTCACCTCTTCTGCCTTTACGTGGTGTCTAAATATCTCGCTGTGGAGTCCCCT
TTCCTTAAGGAAGTTTTATCTGAGCCTTGGAGATTATCAACAAGCCAGACCCCTCAGCAGCAAGTGGAGCTGTTTGACTTGGAGAATAAC
CCAGAGTACGTGTCCAGCGGAGGGGGCTTTGGACCGGTTGCTGATGACGGCTATGGTGTGTCGTACATCCTTGTGGGAGAGAACCTCATC
AATTTCCACATTTCTTCCAAGTTCTCTTGCCCTGAGACGGGGATTATAAGTCAAGGACCAAGTTCAGATACTTGAGACAAAGTGGAAAGT
CTCAGCATATGGAAACAAGGCCTTGGAGGAGACCATGGACATCACCAAGTTCATGTGCTGGGCTGGAAAGAAAAGCCTGTTGATTTTCAC
TTGCTGTGCATTTATTCATCCATTCCATTGCCTCAATGCTGAGAACAGTGCCTGACACATAAAAGATGCTCAATAAATATGTTAAAAGTA

>72671_72671_4_RBFOX2-CPT1A_RBFOX2_chr22_36334895_ENST00000438146_CPT1A_chr11_68571569_ENST00000540367_length(amino acids)=684AA_BP=78
MAEGAQPHQPPQLGPGAAARGMKRESELELPVPGAGGDGADPGLSKRPRTEEAAADGGGGMQNEPLTPGYHGFPARDSQGMVKIFSGRKP
MLYSFQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNS
NYYAMDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRY
FKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDP
DTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDI
PGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTTES
CDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RBFOX2-CPT1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RBFOX2-CPT1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RBFOX2-CPT1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource