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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:RBL1-BCAS1 (FusionGDB2 ID:72717) |
Fusion Gene Summary for RBL1-BCAS1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RBL1-BCAS1 | Fusion gene ID: 72717 | Hgene | Tgene | Gene symbol | RBL1 | BCAS1 | Gene ID | 5933 | 8537 |
| Gene name | RB transcriptional corepressor like 1 | brain enriched myelin associated protein 1 | |
| Synonyms | CP107|PRB1|p107 | AIBC1|NABC1|PMES-2 | |
| Cytomap | 20q11.23 | 20q13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | retinoblastoma-like protein 1107 kDa retinoblastoma-associated proteinretinoblastoma-like 1 | breast carcinoma-amplified sequence 1amplified and overexpressed in breast cancerbreast carcinoma amplified sequence 1novel amplified in breast cancer 1protein having mRNA enriched in synaptosomes 2 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | O75363 | |
| Ensembl transtripts involved in fusion gene | ENST00000344359, ENST00000373664, ENST00000598590, | ENST00000411563, ENST00000371435, ENST00000371440, ENST00000395961, ENST00000434986, | |
| Fusion gene scores | * DoF score | 13 X 9 X 7=819 | 18 X 14 X 9=2268 |
| # samples | 15 | 19 | |
| ** MAII score | log2(15/819*10)=-2.44890095114513 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(19/2268*10)=-3.57734931661128 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RBL1 [Title/Abstract] AND BCAS1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | RBL1(35651053)-BCAS1(52561535), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | RBL1-BCAS1 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | RBL1 | GO:0043550 | regulation of lipid kinase activity | 16286473 |
| Fusion gene breakpoints across RBL1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across BCAS1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | UCEC | TCGA-EY-A547-01A | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
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Fusion Gene ORF analysis for RBL1-BCAS1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000344359 | ENST00000411563 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| 5CDS-intron | ENST00000373664 | ENST00000411563 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| Frame-shift | ENST00000344359 | ENST00000371435 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| Frame-shift | ENST00000373664 | ENST00000371435 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| In-frame | ENST00000344359 | ENST00000371440 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| In-frame | ENST00000344359 | ENST00000395961 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| In-frame | ENST00000344359 | ENST00000434986 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| In-frame | ENST00000373664 | ENST00000371440 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| In-frame | ENST00000373664 | ENST00000395961 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| In-frame | ENST00000373664 | ENST00000434986 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| intron-3CDS | ENST00000598590 | ENST00000371435 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| intron-3CDS | ENST00000598590 | ENST00000371440 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| intron-3CDS | ENST00000598590 | ENST00000395961 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| intron-3CDS | ENST00000598590 | ENST00000434986 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| intron-intron | ENST00000598590 | ENST00000411563 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000373664 | RBL1 | chr20 | 35651053 | - | ENST00000371440 | BCAS1 | chr20 | 52561535 | - | 2764 | 2626 | 67 | 2763 | 899 |
| ENST00000373664 | RBL1 | chr20 | 35651053 | - | ENST00000395961 | BCAS1 | chr20 | 52561535 | - | 4082 | 2626 | 67 | 2700 | 877 |
| ENST00000373664 | RBL1 | chr20 | 35651053 | - | ENST00000434986 | BCAS1 | chr20 | 52561535 | - | 3000 | 2626 | 67 | 2700 | 877 |
| ENST00000344359 | RBL1 | chr20 | 35651053 | - | ENST00000371440 | BCAS1 | chr20 | 52561535 | - | 2758 | 2620 | 61 | 2757 | 899 |
| ENST00000344359 | RBL1 | chr20 | 35651053 | - | ENST00000395961 | BCAS1 | chr20 | 52561535 | - | 4076 | 2620 | 61 | 2694 | 877 |
| ENST00000344359 | RBL1 | chr20 | 35651053 | - | ENST00000434986 | BCAS1 | chr20 | 52561535 | - | 2994 | 2620 | 61 | 2694 | 877 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000373664 | ENST00000371440 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - | 0.000310382 | 0.9996897 |
| ENST00000373664 | ENST00000395961 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - | 0.000295804 | 0.9997042 |
| ENST00000373664 | ENST00000434986 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - | 0.000330263 | 0.9996698 |
| ENST00000344359 | ENST00000371440 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - | 0.000310783 | 0.9996892 |
| ENST00000344359 | ENST00000395961 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - | 0.00029638 | 0.9997036 |
| ENST00000344359 | ENST00000434986 | RBL1 | chr20 | 35651053 | - | BCAS1 | chr20 | 52561535 | - | 0.000331864 | 0.9996681 |
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Fusion Genomic Features for RBL1-BCAS1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for RBL1-BCAS1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:35651053/chr20:52561535) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | BCAS1 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Required for myelination. {ECO:0000250|UniProtKB:Q80YN3}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RBL1 | chr20:35651053 | chr20:52561535 | ENST00000344359 | - | 17 | 21 | 385_584 | 853 | 1015.0 | Region | Domain A |
| Hgene | RBL1 | chr20:35651053 | chr20:52561535 | ENST00000344359 | - | 17 | 21 | 585_780 | 853 | 1015.0 | Region | Spacer |
| Hgene | RBL1 | chr20:35651053 | chr20:52561535 | ENST00000373664 | - | 17 | 22 | 385_584 | 853 | 1069.0 | Region | Domain A |
| Hgene | RBL1 | chr20:35651053 | chr20:52561535 | ENST00000373664 | - | 17 | 22 | 585_780 | 853 | 1069.0 | Region | Spacer |
| Tgene | BCAS1 | chr20:35651053 | chr20:52561535 | ENST00000395961 | 10 | 12 | 565_584 | 560 | 585.0 | Region | Interacts with DYNLL1 AND DYNLL2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RBL1 | chr20:35651053 | chr20:52561535 | ENST00000344359 | - | 17 | 21 | 385_949 | 853 | 1015.0 | Region | Pocket%3B binds T and E1A |
| Hgene | RBL1 | chr20:35651053 | chr20:52561535 | ENST00000344359 | - | 17 | 21 | 781_949 | 853 | 1015.0 | Region | Domain B |
| Hgene | RBL1 | chr20:35651053 | chr20:52561535 | ENST00000373664 | - | 17 | 22 | 385_949 | 853 | 1069.0 | Region | Pocket%3B binds T and E1A |
| Hgene | RBL1 | chr20:35651053 | chr20:52561535 | ENST00000373664 | - | 17 | 22 | 781_949 | 853 | 1069.0 | Region | Domain B |
| Tgene | BCAS1 | chr20:35651053 | chr20:52561535 | ENST00000371440 | 9 | 12 | 565_584 | 569 | 615.0 | Region | Interacts with DYNLL1 AND DYNLL2 |
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Fusion Gene Sequence for RBL1-BCAS1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >72717_72717_1_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000344359_BCAS1_chr20_52561535_ENST00000371440_length(transcript)=2758nt_BP=2620nt CGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGCTGAGGG GGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGCCCTGGA CGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCGCAAAAG CATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTTAATACA ATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAATTTTGA GGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACCACGAAG CCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTTTCGGAT GATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAATAGACA AGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCATCATTGC TGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACTCTTTGA CAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGAGTATGT TCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCGTGACAC CCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTCTACCCC ACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACAGAGTAT TGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTATGAAAAT ACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGTAAACAG ACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACATGTCAGT TCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTACTTTTCC TTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTCAAGGGA CATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCTCCAGGT TTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACATCTTCC CCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACCATTGTC TCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGAAATGCT TATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACCTGGTCA AACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGATGCTGG AGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATTAATTGG TGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTTAGCACT ATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAGGAAGAT ATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTTTTATAT CATGGCAAAGGGACCAAAGCGGATGTTGGATGCTCAAGTGCAAACAGACCCAGTATCCATCGGACCAGTTGGCAAATCCAAGTACACAGG >72717_72717_1_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000344359_BCAS1_chr20_52561535_ENST00000371440_length(amino acids)=899AA_BP=853 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL -------------------------------------------------------------- >72717_72717_2_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000344359_BCAS1_chr20_52561535_ENST00000395961_length(transcript)=4076nt_BP=2620nt CGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGCTGAGGG GGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGCCCTGGA CGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCGCAAAAG CATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTTAATACA ATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAATTTTGA GGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACCACGAAG CCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTTTCGGAT GATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAATAGACA AGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCATCATTGC TGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACTCTTTGA CAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGAGTATGT TCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCGTGACAC CCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTCTACCCC ACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACAGAGTAT TGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTATGAAAAT ACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGTAAACAG ACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACATGTCAGT TCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTACTTTTCC TTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTCAAGGGA CATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCTCCAGGT TTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACATCTTCC CCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACCATTGTC TCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGAAATGCT TATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACCTGGTCA AACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGATGCTGG AGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATTAATTGG TGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTTAGCACT ATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAGGAAGAT ATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTTTTATAT CATGGCAAAGGGACCAAAGCGGATGTTGGATGCTCAAGTGCAAACAGACCCAGTATCCATCGGACCAGTTGGCAAATCCAAGTAAACAAA TCAGCACGGTTCCCACCAGGTTCTCCTGCCACCAAGATGTGTTCTCCTTACTCCATCTCCTCCCCAAACACGCTCCATGTATATATTCTT CTGATGGCCAGCAAATGAAATTCTGCCTAGAAATTAAGCCCGAGCTGTTGTATATTGAGGTGTATTATTTACGTCTCTGGTCCAGTCTTT TCTGGCAAATAACAGTAAAGATGGTTTAGCAGGTCACCTAGTTGGGTCAGAAGAGTCGATGATCACCAAGCAGGAAAGGGAGGGAATAGA GGAATGTGTTCGGGTTAAGTGATGAAAATGGCAGTGGTGGCCGGGCGTGGTGGCTCTCGCCTGTAATCTCAGCACTTTGGGAGGCCGAGG CAGGTGGATCACCTGAGGTCAGGAGTTCAAGACTAGCCTGGCCAACATCATGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGG CATGGTGGCACACACCTGTAGTCCCAGCTACTCGGGAGCCCAACGCACGAGAACCGCTTGTACCCAGGAGGTGGAGGTTGCAGTGAGCCG AAGTTGCACCATTGCACTCCACCCTGGGCGACAGAGCAAGATTCTATCAAAAAAAAAAAAAGGCAGTGGCAAGTAAGTTATAGAAGAGAA ATGCTGCTAGAAGGAATTAAGCGTTGTAGTAAATGCGTGCTTATCCTCTAAGCTTGAAGAAGGGAGACGAAAATCCATTTGTTTAAATTC ACATCTCAAGGAGGGAGAACCCGGGCTGTGTTGGGTGGTTGCCAATTTCCTAGAACGGAATGTGTGGGGTATAGAAAAAGGAATGAATAA GCGTTGTTTTTCAAATAGGGTCCTTGTAAGTTATTGATGAGAGGGAAAAGATTGACTGGGGAGGGCTTAAAATGATTTGGGAAAACAATT GCTTTTGAGGCTCAGTGACAACGGCAAAGATTACAACTTAAAAAAAAAAAATAAATAAAAAATAAAGGAAGTTGCACGGTTATTTTGCAA CACAAGGGGGCGGCAAGGTCCCCATTTTTATCCTGTAATACTGTATCCCTAACAAAGATTTGGTCTCTGCTATCTTACATTATTAATGTT TCTCAGATGGCTGAGGGGCTCGCTTCATCTGTTCCGTCTGACACTTATCTCAAGTGTGTCTGTCATTCCTAATGTTCTCAGGATGTGCTC TGATAAAACCCTCCCCATAACCTCAGTTAATAAAAATTTACAGAAGACTTCTCAAATACCTGAGTTGTTTTTAATACCTGTACAAAGGAG TAAATAGGACCCTGAGTCTATTAAAATGTAATTCAAAGTAGCATATGATTGACTGACAGTCATGTAAACTGTATCTTTCTTTTTCTGATT >72717_72717_2_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000344359_BCAS1_chr20_52561535_ENST00000395961_length(amino acids)=877AA_BP=853 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL -------------------------------------------------------------- >72717_72717_3_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000344359_BCAS1_chr20_52561535_ENST00000434986_length(transcript)=2994nt_BP=2620nt CGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGCTGAGGG GGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGCCCTGGA CGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCGCAAAAG CATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTTAATACA ATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAATTTTGA GGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACCACGAAG CCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTTTCGGAT GATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAATAGACA AGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCATCATTGC TGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACTCTTTGA CAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGAGTATGT TCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCGTGACAC CCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTCTACCCC ACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACAGAGTAT TGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTATGAAAAT ACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGTAAACAG ACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACATGTCAGT TCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTACTTTTCC TTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTCAAGGGA CATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCTCCAGGT TTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACATCTTCC CCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACCATTGTC TCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGAAATGCT TATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACCTGGTCA AACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGATGCTGG AGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATTAATTGG TGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTTAGCACT ATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAGGAAGAT ATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTTTTATAT CATGGCAAAGGGACCAAAGCGGATGTTGGATGCTCAAGTGCAAACAGACCCAGTATCCATCGGACCAGTTGGCAAATCCAAGTAAACAAA TCAGCACGGTTCCCACCAGGTTCTCCTGCCACCAAGATGTGTTCTCCTTACTCCATCTCCTCCCCAAACACGCTCCATGTATATATTCTT CTGATGGCCAGCAAATGAAATTCTGCCTAGAAATTAAGCCCGAGCTGTTGTATATTGAGGTGTATTATTTACGTCTCTGGTCCAGTCTTT TCTGGCAAATAACAGTAAAGATGGTTTAGCAGGTCACCTAGTTGGGTCAGAAGAGTCGATGATCACCAAGCAGGAAAGGGAGGGAATAGA >72717_72717_3_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000344359_BCAS1_chr20_52561535_ENST00000434986_length(amino acids)=877AA_BP=853 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL -------------------------------------------------------------- >72717_72717_4_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000373664_BCAS1_chr20_52561535_ENST00000371440_length(transcript)=2764nt_BP=2626nt GGGTAGCGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGC TGAGGGGGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGC CCTGGACGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCG CAAAAGCATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTT AATACAATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAA TTTTGAGGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACC ACGAAGCCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTT TCGGATGATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAA TAGACAAGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCAT CATTGCTGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACT CTTTGACAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGA GTATGTTCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCG TGACACCCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTC TACCCCACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACA GAGTATTGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTAT GAAAATACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGT AAACAGACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACAT GTCAGTTCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTAC TTTTCCTTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTC AAGGGACATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCT CCAGGTTTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACA TCTTCCCCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACC ATTGTCTCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGA AATGCTTATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACC TGGTCAAACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGA TGCTGGAGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATT AATTGGTGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTT AGCACTATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAG GAAGATATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTT TTATATCATGGCAAAGGGACCAAAGCGGATGTTGGATGCTCAAGTGCAAACAGACCCAGTATCCATCGGACCAGTTGGCAAATCCAAGTA >72717_72717_4_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000373664_BCAS1_chr20_52561535_ENST00000371440_length(amino acids)=899AA_BP=853 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL -------------------------------------------------------------- >72717_72717_5_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000373664_BCAS1_chr20_52561535_ENST00000395961_length(transcript)=4082nt_BP=2626nt GGGTAGCGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGC TGAGGGGGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGC CCTGGACGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCG CAAAAGCATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTT AATACAATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAA TTTTGAGGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACC ACGAAGCCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTT TCGGATGATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAA TAGACAAGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCAT CATTGCTGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACT CTTTGACAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGA GTATGTTCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCG TGACACCCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTC TACCCCACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACA GAGTATTGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTAT GAAAATACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGT AAACAGACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACAT GTCAGTTCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTAC TTTTCCTTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTC AAGGGACATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCT CCAGGTTTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACA TCTTCCCCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACC ATTGTCTCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGA AATGCTTATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACC TGGTCAAACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGA TGCTGGAGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATT AATTGGTGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTT AGCACTATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAG GAAGATATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTT TTATATCATGGCAAAGGGACCAAAGCGGATGTTGGATGCTCAAGTGCAAACAGACCCAGTATCCATCGGACCAGTTGGCAAATCCAAGTA AACAAATCAGCACGGTTCCCACCAGGTTCTCCTGCCACCAAGATGTGTTCTCCTTACTCCATCTCCTCCCCAAACACGCTCCATGTATAT ATTCTTCTGATGGCCAGCAAATGAAATTCTGCCTAGAAATTAAGCCCGAGCTGTTGTATATTGAGGTGTATTATTTACGTCTCTGGTCCA GTCTTTTCTGGCAAATAACAGTAAAGATGGTTTAGCAGGTCACCTAGTTGGGTCAGAAGAGTCGATGATCACCAAGCAGGAAAGGGAGGG AATAGAGGAATGTGTTCGGGTTAAGTGATGAAAATGGCAGTGGTGGCCGGGCGTGGTGGCTCTCGCCTGTAATCTCAGCACTTTGGGAGG CCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCAAGACTAGCCTGGCCAACATCATGAAACCCCGTCTCTACTAAAAATACAAAAATTA GCCAGGCATGGTGGCACACACCTGTAGTCCCAGCTACTCGGGAGCCCAACGCACGAGAACCGCTTGTACCCAGGAGGTGGAGGTTGCAGT GAGCCGAAGTTGCACCATTGCACTCCACCCTGGGCGACAGAGCAAGATTCTATCAAAAAAAAAAAAAGGCAGTGGCAAGTAAGTTATAGA AGAGAAATGCTGCTAGAAGGAATTAAGCGTTGTAGTAAATGCGTGCTTATCCTCTAAGCTTGAAGAAGGGAGACGAAAATCCATTTGTTT AAATTCACATCTCAAGGAGGGAGAACCCGGGCTGTGTTGGGTGGTTGCCAATTTCCTAGAACGGAATGTGTGGGGTATAGAAAAAGGAAT GAATAAGCGTTGTTTTTCAAATAGGGTCCTTGTAAGTTATTGATGAGAGGGAAAAGATTGACTGGGGAGGGCTTAAAATGATTTGGGAAA ACAATTGCTTTTGAGGCTCAGTGACAACGGCAAAGATTACAACTTAAAAAAAAAAAATAAATAAAAAATAAAGGAAGTTGCACGGTTATT TTGCAACACAAGGGGGCGGCAAGGTCCCCATTTTTATCCTGTAATACTGTATCCCTAACAAAGATTTGGTCTCTGCTATCTTACATTATT AATGTTTCTCAGATGGCTGAGGGGCTCGCTTCATCTGTTCCGTCTGACACTTATCTCAAGTGTGTCTGTCATTCCTAATGTTCTCAGGAT GTGCTCTGATAAAACCCTCCCCATAACCTCAGTTAATAAAAATTTACAGAAGACTTCTCAAATACCTGAGTTGTTTTTAATACCTGTACA AAGGAGTAAATAGGACCCTGAGTCTATTAAAATGTAATTCAAAGTAGCATATGATTGACTGACAGTCATGTAAACTGTATCTTTCTTTTT >72717_72717_5_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000373664_BCAS1_chr20_52561535_ENST00000395961_length(amino acids)=877AA_BP=853 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL -------------------------------------------------------------- >72717_72717_6_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000373664_BCAS1_chr20_52561535_ENST00000434986_length(transcript)=3000nt_BP=2626nt GGGTAGCGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGC TGAGGGGGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGC CCTGGACGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCG CAAAAGCATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTT AATACAATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAA TTTTGAGGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACC ACGAAGCCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTT TCGGATGATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAA TAGACAAGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCAT CATTGCTGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACT CTTTGACAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGA GTATGTTCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCG TGACACCCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTC TACCCCACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACA GAGTATTGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTAT GAAAATACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGT AAACAGACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACAT GTCAGTTCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTAC TTTTCCTTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTC AAGGGACATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCT CCAGGTTTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACA TCTTCCCCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACC ATTGTCTCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGA AATGCTTATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACC TGGTCAAACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGA TGCTGGAGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATT AATTGGTGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTT AGCACTATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAG GAAGATATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTT TTATATCATGGCAAAGGGACCAAAGCGGATGTTGGATGCTCAAGTGCAAACAGACCCAGTATCCATCGGACCAGTTGGCAAATCCAAGTA AACAAATCAGCACGGTTCCCACCAGGTTCTCCTGCCACCAAGATGTGTTCTCCTTACTCCATCTCCTCCCCAAACACGCTCCATGTATAT ATTCTTCTGATGGCCAGCAAATGAAATTCTGCCTAGAAATTAAGCCCGAGCTGTTGTATATTGAGGTGTATTATTTACGTCTCTGGTCCA GTCTTTTCTGGCAAATAACAGTAAAGATGGTTTAGCAGGTCACCTAGTTGGGTCAGAAGAGTCGATGATCACCAAGCAGGAAAGGGAGGG >72717_72717_6_RBL1-BCAS1_RBL1_chr20_35651053_ENST00000373664_BCAS1_chr20_52561535_ENST00000434986_length(amino acids)=877AA_BP=853 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for RBL1-BCAS1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for RBL1-BCAS1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for RBL1-BCAS1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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