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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:RBL1-NDRG3 (FusionGDB2 ID:72728)

Fusion Gene Summary for RBL1-NDRG3

Fusion gene summary

Fusion gene information	Fusion gene name: RBL1-NDRG3
	Fusion gene ID: 72728
		Hgene	Tgene
	Gene symbol	RBL1	NDRG3
	Gene ID	5933	57446
	Gene name	RB transcriptional corepressor like 1	NDRG family member 3
	Synonyms	CP107\|PRB1\|p107	-
	Cytomap	20q11.23	20q11.23
	Type of gene	protein-coding	protein-coding
	Description	retinoblastoma-like protein 1107 kDa retinoblastoma-associated proteinretinoblastoma-like 1	protein NDRG3N-myc downstream-regulated gene 3 protein
	Modification date	20200313	20200313
	UniProtAcc	.	Q9UGV2
	Ensembl transtripts involved in fusion gene	ENST00000344359, ENST00000373664, ENST00000598590,	ENST00000373773, ENST00000349004, ENST00000359675, ENST00000540765, ENST00000373803,
Fusion gene scores	* DoF score	13 X 9 X 7=819	9 X 11 X 5=495
	# samples	15	12
	** MAII score	log2(15/819*10)=-2.44890095114513 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(12/495*10)=-2.04439411935845 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: RBL1 [Title/Abstract] AND NDRG3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	RBL1(35651053)-NDRG3(35335410), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	RBL1	GO:0043550	regulation of lipid kinase activity	16286473

Fusion gene breakpoints across RBL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across NDRG3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-C8-A12T-01A	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
ChimerDB4	BRCA	TCGA-C8-A12T	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-

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Fusion Gene ORF analysis for RBL1-NDRG3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000344359	ENST00000373773	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
5CDS-5UTR	ENST00000344359	ENST00000373773	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
5CDS-5UTR	ENST00000373664	ENST00000373773	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
5CDS-5UTR	ENST00000373664	ENST00000373773	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000344359	ENST00000349004	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000344359	ENST00000349004	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000344359	ENST00000359675	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000344359	ENST00000359675	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000344359	ENST00000540765	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000344359	ENST00000540765	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000373664	ENST00000349004	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000373664	ENST00000349004	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000373664	ENST00000359675	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000373664	ENST00000359675	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000373664	ENST00000540765	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
5CDS-intron	ENST00000373664	ENST00000540765	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
In-frame	ENST00000344359	ENST00000373803	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
In-frame	ENST00000344359	ENST00000373803	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
In-frame	ENST00000373664	ENST00000373803	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
In-frame	ENST00000373664	ENST00000373803	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
intron-3CDS	ENST00000598590	ENST00000373803	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
intron-3CDS	ENST00000598590	ENST00000373803	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
intron-5UTR	ENST00000598590	ENST00000373773	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
intron-5UTR	ENST00000598590	ENST00000373773	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
intron-intron	ENST00000598590	ENST00000349004	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
intron-intron	ENST00000598590	ENST00000349004	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
intron-intron	ENST00000598590	ENST00000359675	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
intron-intron	ENST00000598590	ENST00000359675	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-
intron-intron	ENST00000598590	ENST00000540765	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-
intron-intron	ENST00000598590	ENST00000540765	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000373664	RBL1	chr20	35651053	-	ENST00000373803	NDRG3	chr20	35335410	-	5490	2626	67	3735	1222
ENST00000344359	RBL1	chr20	35651053	-	ENST00000373803	NDRG3	chr20	35335410	-	5484	2620	61	3729	1222
ENST00000373664	RBL1	chr20	35651052	-	ENST00000373803	NDRG3	chr20	35335410	-	5490	2626	67	3735	1222
ENST00000344359	RBL1	chr20	35651052	-	ENST00000373803	NDRG3	chr20	35335410	-	5484	2620	61	3729	1222

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000373664	ENST00000373803	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-	0.000169312	0.9998306
ENST00000344359	ENST00000373803	RBL1	chr20	35651053	-	NDRG3	chr20	35335410	-	0.000167963	0.99983203
ENST00000373664	ENST00000373803	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-	0.000169312	0.9998306
ENST00000344359	ENST00000373803	RBL1	chr20	35651052	-	NDRG3	chr20	35335410	-	0.000167963	0.99983203

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Fusion Genomic Features for RBL1-NDRG3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RBL1-NDRG3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:35651053/chr20:35335410)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	NDRG3 Q9UGV2
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

RBL1

chr20:35651052

chr20:35335410

ENST00000344359

385_584

853

1015.0

Region

Domain A

Hgene

RBL1

chr20:35651052

chr20:35335410

ENST00000344359

585_780

853

1015.0

Region

Spacer

Hgene

RBL1

chr20:35651052

chr20:35335410

ENST00000373664

385_584

853

1069.0

Region

Domain A

Hgene

RBL1

chr20:35651052

chr20:35335410

ENST00000373664

585_780

853

1069.0

Region

Spacer

Hgene

RBL1

chr20:35651053

chr20:35335410

ENST00000344359

385_584

853

1015.0

Region

Domain A

Hgene

RBL1

chr20:35651053

chr20:35335410

ENST00000344359

585_780

853

1015.0

Region

Spacer

Hgene

RBL1

chr20:35651053

chr20:35335410

ENST00000373664

385_584

853

1069.0

Region

Domain A

Hgene

RBL1

chr20:35651053

chr20:35335410

ENST00000373664

585_780

853

1069.0

Region

Spacer

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

RBL1

chr20:35651052

chr20:35335410

ENST00000344359

385_949

853

1015.0

Region

Pocket%3B binds T and E1A

Hgene

RBL1

chr20:35651052

chr20:35335410

ENST00000344359

781_949

853

1015.0

Region

Domain B

Hgene

RBL1

chr20:35651052

chr20:35335410

ENST00000373664

385_949

853

1069.0

Region

Pocket%3B binds T and E1A

Hgene

RBL1

chr20:35651052

chr20:35335410

ENST00000373664

781_949

853

1069.0

Region

Domain B

Hgene

RBL1

chr20:35651053

chr20:35335410

ENST00000344359

385_949

853

1015.0

Region

Pocket%3B binds T and E1A

Hgene

RBL1

chr20:35651053

chr20:35335410

ENST00000344359

781_949

853

1015.0

Region

Domain B

Hgene

RBL1

chr20:35651053

chr20:35335410

ENST00000373664

385_949

853

1069.0

Region

Pocket%3B binds T and E1A

Hgene

RBL1

chr20:35651053

chr20:35335410

ENST00000373664

781_949

853

1069.0

Region

Domain B

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Fusion Gene Sequence for RBL1-NDRG3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>72728_72728_1_RBL1-NDRG3_RBL1_chr20_35651052_ENST00000344359_NDRG3_chr20_35335410_ENST00000373803_length(transcript)=5484nt_BP=2620nt
CGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGCTGAGGG
GGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGCCCTGGA
CGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCGCAAAAG
CATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTTAATACA
ATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAATTTTGA
GGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACCACGAAG
CCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTTTCGGAT
GATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAATAGACA
AGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCATCATTGC
TGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACTCTTTGA
CAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGAGTATGT
TCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCGTGACAC
CCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTCTACCCC
ACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACAGAGTAT
TGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTATGAAAAT
ACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGTAAACAG
ACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACATGTCAGT
TCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTACTTTTCC
TTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTCAAGGGA
CATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCTCCAGGT
TTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACATCTTCC
CCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACCATTGTC
TCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGAAATGCT
TATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACCTGGTCA
AACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGATGCTGG
AGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATTAATTGG
TGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTTAGCACT
ATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAGGAAGAT
ATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTTTTATAT
CATGGCAAAGAATGGTACAAGAAACTTCCAGGACTTTGACTGTCAGGAACATGATATAGAAACAACTCATGGTGTGGTCCACGTCACTAT
AAGAGGCTTACCCAAAGGAAACAGACCAGTTATACTAACATATCATGACATTGGCCTCAACCATAAATCCTGTTTCAATGCATTCTTTAA
CTTTGAGGATATGCAAGAGATCACCCAGCACTTTGCTGTCTGTCATGTGGATGCCCCAGGCCAGCAGGAAGGTGCACCCTCTTTCCCAAC
AGGGTATCAGTACCCCACAATGGATGAGCTGGCTGAAATGCTGCCTCCTGTTCTTACCCACCTAAGCCTGAAAAGCATCATTGGAATTGG
AGTTGGAGCTGGAGCTTACATCCTCAGCAGATTTGCACTCAACCATCCAGAGCTTGTGGAAGGCCTTGTGCTCATTAATGTTGACCCTTG
CGCTAAAGGCTGGATTGACTGGGCAGCTTCCAAACTCTCTGGCCTGACAACCAATGTTGTGGACATTATTTTGGCTCATCACTTTGGGCA
GGAAGAGTTACAGGCCAACCTGGACCTGATCCAAACCTACAGAATGCATATTGCCCAAGACATCAACCAAGACAACCTGCAGCTCTTCTT
GAATTCCTACAATGGACGCAGAGACCTGGAGATCGAAAGACCCATACTGGGCCAAAATGATAACAAATCAAAAACATTAAAGTGTTCTAC
TTTACTGGTGGTAGGGGACAATTCGCCTGCAGTTGAGGCTGTGGTCGAATGCAATTCCCGCCTGAACCCTATAAATACAACTTTGCTAAA
GATGGCGGACTGTGGGGGACTGCCCCAGGTAGTTCAGCCTGGGAAGCTCACCGAGGCCTTCAAGTACTTTTTGCAGGGAATGGGCTACAT
CCCGTATGTGCAGCTCAGTCACCTGAGCACCGAGTCAGTACCATCTGCCAGCATGACTCGGCTCGCCCGATCACGAACCCACTCAACCTC
GAGTAGCCTCGGCTCTGGAGAAAGTCCCTTCAGCCGGTCTGTCACCAGCAATCAGTCAGATGGAACTCAAGAATCCTGTGAGTCCCCTGA
TGTCCTGGACAGACACCAGACCATGGAGGTGTCCTGCTAAGCAGATGCTCCTCCCCTGGACCATTGCAAGTCCATCCTTCAAATGACCAC
TCCATAATATAACATTTCATCCAGTAAACTGGCCTCTACTATCTTTAACTCATGCATGGCCACTGAACCTCTCTCTAGTAGCCTGGATTT
ATCATTCTCTCTGCCTGCCCACCCCCTTTTTTGTATAGCCCAAGAACCACTTCCATGCCATACTGTAACATTCCAACATCTTTAGCTGAT
CAGATCTCTCCATATCCTCTCTTGCCAGCTTTTTCCCGTGCTCCCCCAACTATGTATCAGATAAGATTCTTTGATCCCGACTCTGTGTGT
GCGAGCACGCGTGTCTGTGTTTGTGTGTGCATAGTTCTGTGGTTTTAGACACGCTTTCTTGTAGTGCTTCTGCAAAAAACAAAAAAGGGA
CTTATTTTGCATTCTCAATGGTGTTTTTAAGGGAATTAGGCAGAACAGATTTCTAGGTTGGGTAGGCCACTGCATTCTCTTTTGTTTGCA
AATTGGTCAACAAAATTTGCAAAGTGATTTCAGGAGAGAGCAGCTTTGAGGAATGTGGAAAATCATAATTGCCGTCTGGACCATTGATTG
ATTGTGACCAGTAGCAGAAGGGTGCCTGTTACATAGAGAGGCTCCTTCTGTCCAAATGAATTTCTGTATACTCTTCTATAAATAAAAGGG
AGGAATATATTCTGCTGGAAGCCCATGAACCATCGCTGAGGTTCTGATACAACATAGAGTTTTTTCCAAGGAGTGAATGTGGTTTAATTA
CTGGACTCTCTTAGCACAGGAAGGTGGAAACAAAATGCCAGGCCTCTGCTCTGAAGAGCAAAACTGCTGTCGCTGCAGTATCTGATACCA
GACATCCACATATCCACAAGAAGTGCCTCTTAGGTCTGTGACAGAGAGTGTGTCTCCATTCCTCAGTTCCCAGAAAGGGGAGAGGTTTGG
CCTAAAAAGCATGTAGATGGGGGAGAAATGGGTGGGGGGAGAGGAACAGCCATTAACACAGTATCATGTTTAACAAGTATAGCCTTGATT
TCAGTAGATGTAATGGAAGCCAAATTAAATTGATACAGAACCCATTTCTCAGAGTCTTTTTTTTTTTTTGAGACAGAGTCTCGCTGTTAC
CCAGGCTGGAGTGCAATGGCGCAAACTTGGCTCACTGCAACCTCTGCCCCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAG
CTGAGACTACAGGCACCTGCCACCATACCCAGCTAAGTTATGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAGGCTGGTCTCA
AACTCCTGACCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGTCATTGCTCCCAGCCATTAGAAAGAT
TGTTAATCCTATGAACTCCCTTTTGTAGGAGAGAAAGGGCCAATCTGTAGGGGTAGCCCTGTCCAGGTAAAGTTGTTTTCAGCCTCATGT
CTACTGTTAGGTGAGGGAGTCACAGCCAGACAGAGAGTATTGCTGGAGGGTGAGAGAATTGTGGAGACCAACTACCACATAGCAAGAGCC
CAGCTCTTGGGAGCATTGAGATGTAAGCTCAGGGTTACACAGTTCCAAATCTTGGGAAGGGGCTTTTCAGACAGACTGTTTGCTTTCTGC

>72728_72728_1_RBL1-NDRG3_RBL1_chr20_35651052_ENST00000344359_NDRG3_chr20_35335410_ENST00000373803_length(amino acids)=1222AA_BP=0
MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI
LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL
FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY
FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE
KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP
GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV
IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG
SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI
PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL
DVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVILTYHDIGLN
HKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVE
GLVLINVDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIERPILGQND
NKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPYVQLSHLSTESVPSASMTR

--------------------------------------------------------------
>72728_72728_2_RBL1-NDRG3_RBL1_chr20_35651052_ENST00000373664_NDRG3_chr20_35335410_ENST00000373803_length(transcript)=5490nt_BP=2626nt
GGGTAGCGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGC
TGAGGGGGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGC
CCTGGACGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCG
CAAAAGCATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTT
AATACAATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAA
TTTTGAGGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACC
ACGAAGCCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTT
TCGGATGATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAA
TAGACAAGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCAT
CATTGCTGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACT
CTTTGACAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGA
GTATGTTCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCG
TGACACCCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTC
TACCCCACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACA
GAGTATTGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTAT
GAAAATACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGT
AAACAGACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACAT
GTCAGTTCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTAC
TTTTCCTTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTC
AAGGGACATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCT
CCAGGTTTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACA
TCTTCCCCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACC
ATTGTCTCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGA
AATGCTTATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACC
TGGTCAAACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGA
TGCTGGAGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATT
AATTGGTGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTT
AGCACTATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAG
GAAGATATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTT
TTATATCATGGCAAAGAATGGTACAAGAAACTTCCAGGACTTTGACTGTCAGGAACATGATATAGAAACAACTCATGGTGTGGTCCACGT
CACTATAAGAGGCTTACCCAAAGGAAACAGACCAGTTATACTAACATATCATGACATTGGCCTCAACCATAAATCCTGTTTCAATGCATT
CTTTAACTTTGAGGATATGCAAGAGATCACCCAGCACTTTGCTGTCTGTCATGTGGATGCCCCAGGCCAGCAGGAAGGTGCACCCTCTTT
CCCAACAGGGTATCAGTACCCCACAATGGATGAGCTGGCTGAAATGCTGCCTCCTGTTCTTACCCACCTAAGCCTGAAAAGCATCATTGG
AATTGGAGTTGGAGCTGGAGCTTACATCCTCAGCAGATTTGCACTCAACCATCCAGAGCTTGTGGAAGGCCTTGTGCTCATTAATGTTGA
CCCTTGCGCTAAAGGCTGGATTGACTGGGCAGCTTCCAAACTCTCTGGCCTGACAACCAATGTTGTGGACATTATTTTGGCTCATCACTT
TGGGCAGGAAGAGTTACAGGCCAACCTGGACCTGATCCAAACCTACAGAATGCATATTGCCCAAGACATCAACCAAGACAACCTGCAGCT
CTTCTTGAATTCCTACAATGGACGCAGAGACCTGGAGATCGAAAGACCCATACTGGGCCAAAATGATAACAAATCAAAAACATTAAAGTG
TTCTACTTTACTGGTGGTAGGGGACAATTCGCCTGCAGTTGAGGCTGTGGTCGAATGCAATTCCCGCCTGAACCCTATAAATACAACTTT
GCTAAAGATGGCGGACTGTGGGGGACTGCCCCAGGTAGTTCAGCCTGGGAAGCTCACCGAGGCCTTCAAGTACTTTTTGCAGGGAATGGG
CTACATCCCGTATGTGCAGCTCAGTCACCTGAGCACCGAGTCAGTACCATCTGCCAGCATGACTCGGCTCGCCCGATCACGAACCCACTC
AACCTCGAGTAGCCTCGGCTCTGGAGAAAGTCCCTTCAGCCGGTCTGTCACCAGCAATCAGTCAGATGGAACTCAAGAATCCTGTGAGTC
CCCTGATGTCCTGGACAGACACCAGACCATGGAGGTGTCCTGCTAAGCAGATGCTCCTCCCCTGGACCATTGCAAGTCCATCCTTCAAAT
GACCACTCCATAATATAACATTTCATCCAGTAAACTGGCCTCTACTATCTTTAACTCATGCATGGCCACTGAACCTCTCTCTAGTAGCCT
GGATTTATCATTCTCTCTGCCTGCCCACCCCCTTTTTTGTATAGCCCAAGAACCACTTCCATGCCATACTGTAACATTCCAACATCTTTA
GCTGATCAGATCTCTCCATATCCTCTCTTGCCAGCTTTTTCCCGTGCTCCCCCAACTATGTATCAGATAAGATTCTTTGATCCCGACTCT
GTGTGTGCGAGCACGCGTGTCTGTGTTTGTGTGTGCATAGTTCTGTGGTTTTAGACACGCTTTCTTGTAGTGCTTCTGCAAAAAACAAAA
AAGGGACTTATTTTGCATTCTCAATGGTGTTTTTAAGGGAATTAGGCAGAACAGATTTCTAGGTTGGGTAGGCCACTGCATTCTCTTTTG
TTTGCAAATTGGTCAACAAAATTTGCAAAGTGATTTCAGGAGAGAGCAGCTTTGAGGAATGTGGAAAATCATAATTGCCGTCTGGACCAT
TGATTGATTGTGACCAGTAGCAGAAGGGTGCCTGTTACATAGAGAGGCTCCTTCTGTCCAAATGAATTTCTGTATACTCTTCTATAAATA
AAAGGGAGGAATATATTCTGCTGGAAGCCCATGAACCATCGCTGAGGTTCTGATACAACATAGAGTTTTTTCCAAGGAGTGAATGTGGTT
TAATTACTGGACTCTCTTAGCACAGGAAGGTGGAAACAAAATGCCAGGCCTCTGCTCTGAAGAGCAAAACTGCTGTCGCTGCAGTATCTG
ATACCAGACATCCACATATCCACAAGAAGTGCCTCTTAGGTCTGTGACAGAGAGTGTGTCTCCATTCCTCAGTTCCCAGAAAGGGGAGAG
GTTTGGCCTAAAAAGCATGTAGATGGGGGAGAAATGGGTGGGGGGAGAGGAACAGCCATTAACACAGTATCATGTTTAACAAGTATAGCC
TTGATTTCAGTAGATGTAATGGAAGCCAAATTAAATTGATACAGAACCCATTTCTCAGAGTCTTTTTTTTTTTTTGAGACAGAGTCTCGC
TGTTACCCAGGCTGGAGTGCAATGGCGCAAACTTGGCTCACTGCAACCTCTGCCCCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCC
GAGTAGCTGAGACTACAGGCACCTGCCACCATACCCAGCTAAGTTATGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAGGCTG
GTCTCAAACTCCTGACCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGTCATTGCTCCCAGCCATTAG
AAAGATTGTTAATCCTATGAACTCCCTTTTGTAGGAGAGAAAGGGCCAATCTGTAGGGGTAGCCCTGTCCAGGTAAAGTTGTTTTCAGCC
TCATGTCTACTGTTAGGTGAGGGAGTCACAGCCAGACAGAGAGTATTGCTGGAGGGTGAGAGAATTGTGGAGACCAACTACCACATAGCA
AGAGCCCAGCTCTTGGGAGCATTGAGATGTAAGCTCAGGGTTACACAGTTCCAAATCTTGGGAAGGGGCTTTTCAGACAGACTGTTTGCT
TTCTGCTGAGATAAGGAATGCATCACTCTGCCAGAGTATGACTTTTTACAGATTATTAAATAAAGCTGCATATGTCTCATTGTTACCTGA

>72728_72728_2_RBL1-NDRG3_RBL1_chr20_35651052_ENST00000373664_NDRG3_chr20_35335410_ENST00000373803_length(amino acids)=1222AA_BP=0
MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI
LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL
FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY
FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE
KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP
GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV
IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG
SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI
PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL
DVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVILTYHDIGLN
HKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVE
GLVLINVDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIERPILGQND
NKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPYVQLSHLSTESVPSASMTR

--------------------------------------------------------------
>72728_72728_3_RBL1-NDRG3_RBL1_chr20_35651053_ENST00000344359_NDRG3_chr20_35335410_ENST00000373803_length(transcript)=5484nt_BP=2620nt
CGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGCTGAGGG
GGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGCCCTGGA
CGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCGCAAAAG
CATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTTAATACA
ATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAATTTTGA
GGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACCACGAAG
CCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTTTCGGAT
GATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAATAGACA
AGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCATCATTGC
TGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACTCTTTGA
CAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGAGTATGT
TCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCGTGACAC
CCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTCTACCCC
ACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACAGAGTAT
TGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTATGAAAAT
ACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGTAAACAG
ACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACATGTCAGT
TCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTACTTTTCC
TTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTCAAGGGA
CATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCTCCAGGT
TTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACATCTTCC
CCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACCATTGTC
TCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGAAATGCT
TATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACCTGGTCA
AACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGATGCTGG
AGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATTAATTGG
TGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTTAGCACT
ATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAGGAAGAT
ATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTTTTATAT
CATGGCAAAGAATGGTACAAGAAACTTCCAGGACTTTGACTGTCAGGAACATGATATAGAAACAACTCATGGTGTGGTCCACGTCACTAT
AAGAGGCTTACCCAAAGGAAACAGACCAGTTATACTAACATATCATGACATTGGCCTCAACCATAAATCCTGTTTCAATGCATTCTTTAA
CTTTGAGGATATGCAAGAGATCACCCAGCACTTTGCTGTCTGTCATGTGGATGCCCCAGGCCAGCAGGAAGGTGCACCCTCTTTCCCAAC
AGGGTATCAGTACCCCACAATGGATGAGCTGGCTGAAATGCTGCCTCCTGTTCTTACCCACCTAAGCCTGAAAAGCATCATTGGAATTGG
AGTTGGAGCTGGAGCTTACATCCTCAGCAGATTTGCACTCAACCATCCAGAGCTTGTGGAAGGCCTTGTGCTCATTAATGTTGACCCTTG
CGCTAAAGGCTGGATTGACTGGGCAGCTTCCAAACTCTCTGGCCTGACAACCAATGTTGTGGACATTATTTTGGCTCATCACTTTGGGCA
GGAAGAGTTACAGGCCAACCTGGACCTGATCCAAACCTACAGAATGCATATTGCCCAAGACATCAACCAAGACAACCTGCAGCTCTTCTT
GAATTCCTACAATGGACGCAGAGACCTGGAGATCGAAAGACCCATACTGGGCCAAAATGATAACAAATCAAAAACATTAAAGTGTTCTAC
TTTACTGGTGGTAGGGGACAATTCGCCTGCAGTTGAGGCTGTGGTCGAATGCAATTCCCGCCTGAACCCTATAAATACAACTTTGCTAAA
GATGGCGGACTGTGGGGGACTGCCCCAGGTAGTTCAGCCTGGGAAGCTCACCGAGGCCTTCAAGTACTTTTTGCAGGGAATGGGCTACAT
CCCGTATGTGCAGCTCAGTCACCTGAGCACCGAGTCAGTACCATCTGCCAGCATGACTCGGCTCGCCCGATCACGAACCCACTCAACCTC
GAGTAGCCTCGGCTCTGGAGAAAGTCCCTTCAGCCGGTCTGTCACCAGCAATCAGTCAGATGGAACTCAAGAATCCTGTGAGTCCCCTGA
TGTCCTGGACAGACACCAGACCATGGAGGTGTCCTGCTAAGCAGATGCTCCTCCCCTGGACCATTGCAAGTCCATCCTTCAAATGACCAC
TCCATAATATAACATTTCATCCAGTAAACTGGCCTCTACTATCTTTAACTCATGCATGGCCACTGAACCTCTCTCTAGTAGCCTGGATTT
ATCATTCTCTCTGCCTGCCCACCCCCTTTTTTGTATAGCCCAAGAACCACTTCCATGCCATACTGTAACATTCCAACATCTTTAGCTGAT
CAGATCTCTCCATATCCTCTCTTGCCAGCTTTTTCCCGTGCTCCCCCAACTATGTATCAGATAAGATTCTTTGATCCCGACTCTGTGTGT
GCGAGCACGCGTGTCTGTGTTTGTGTGTGCATAGTTCTGTGGTTTTAGACACGCTTTCTTGTAGTGCTTCTGCAAAAAACAAAAAAGGGA
CTTATTTTGCATTCTCAATGGTGTTTTTAAGGGAATTAGGCAGAACAGATTTCTAGGTTGGGTAGGCCACTGCATTCTCTTTTGTTTGCA
AATTGGTCAACAAAATTTGCAAAGTGATTTCAGGAGAGAGCAGCTTTGAGGAATGTGGAAAATCATAATTGCCGTCTGGACCATTGATTG
ATTGTGACCAGTAGCAGAAGGGTGCCTGTTACATAGAGAGGCTCCTTCTGTCCAAATGAATTTCTGTATACTCTTCTATAAATAAAAGGG
AGGAATATATTCTGCTGGAAGCCCATGAACCATCGCTGAGGTTCTGATACAACATAGAGTTTTTTCCAAGGAGTGAATGTGGTTTAATTA
CTGGACTCTCTTAGCACAGGAAGGTGGAAACAAAATGCCAGGCCTCTGCTCTGAAGAGCAAAACTGCTGTCGCTGCAGTATCTGATACCA
GACATCCACATATCCACAAGAAGTGCCTCTTAGGTCTGTGACAGAGAGTGTGTCTCCATTCCTCAGTTCCCAGAAAGGGGAGAGGTTTGG
CCTAAAAAGCATGTAGATGGGGGAGAAATGGGTGGGGGGAGAGGAACAGCCATTAACACAGTATCATGTTTAACAAGTATAGCCTTGATT
TCAGTAGATGTAATGGAAGCCAAATTAAATTGATACAGAACCCATTTCTCAGAGTCTTTTTTTTTTTTTGAGACAGAGTCTCGCTGTTAC
CCAGGCTGGAGTGCAATGGCGCAAACTTGGCTCACTGCAACCTCTGCCCCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAG
CTGAGACTACAGGCACCTGCCACCATACCCAGCTAAGTTATGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAGGCTGGTCTCA
AACTCCTGACCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGTCATTGCTCCCAGCCATTAGAAAGAT
TGTTAATCCTATGAACTCCCTTTTGTAGGAGAGAAAGGGCCAATCTGTAGGGGTAGCCCTGTCCAGGTAAAGTTGTTTTCAGCCTCATGT
CTACTGTTAGGTGAGGGAGTCACAGCCAGACAGAGAGTATTGCTGGAGGGTGAGAGAATTGTGGAGACCAACTACCACATAGCAAGAGCC
CAGCTCTTGGGAGCATTGAGATGTAAGCTCAGGGTTACACAGTTCCAAATCTTGGGAAGGGGCTTTTCAGACAGACTGTTTGCTTTCTGC

>72728_72728_3_RBL1-NDRG3_RBL1_chr20_35651053_ENST00000344359_NDRG3_chr20_35335410_ENST00000373803_length(amino acids)=1222AA_BP=0
MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI
LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL
FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY
FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE
KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP
GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV
IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG
SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI
PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL
DVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVILTYHDIGLN
HKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVE
GLVLINVDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIERPILGQND
NKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPYVQLSHLSTESVPSASMTR

--------------------------------------------------------------
>72728_72728_4_RBL1-NDRG3_RBL1_chr20_35651053_ENST00000373664_NDRG3_chr20_35335410_ENST00000373803_length(transcript)=5490nt_BP=2626nt
GGGTAGCGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGC
TGAGGGGGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGC
CCTGGACGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCG
CAAAAGCATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTT
AATACAATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAA
TTTTGAGGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACC
ACGAAGCCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTT
TCGGATGATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAA
TAGACAAGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCAT
CATTGCTGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACT
CTTTGACAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGA
GTATGTTCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCG
TGACACCCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTC
TACCCCACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACA
GAGTATTGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTAT
GAAAATACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGT
AAACAGACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACAT
GTCAGTTCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTAC
TTTTCCTTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTC
AAGGGACATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCT
CCAGGTTTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACA
TCTTCCCCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACC
ATTGTCTCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGA
AATGCTTATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACC
TGGTCAAACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGA
TGCTGGAGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATT
AATTGGTGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTT
AGCACTATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAG
GAAGATATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTT
TTATATCATGGCAAAGAATGGTACAAGAAACTTCCAGGACTTTGACTGTCAGGAACATGATATAGAAACAACTCATGGTGTGGTCCACGT
CACTATAAGAGGCTTACCCAAAGGAAACAGACCAGTTATACTAACATATCATGACATTGGCCTCAACCATAAATCCTGTTTCAATGCATT
CTTTAACTTTGAGGATATGCAAGAGATCACCCAGCACTTTGCTGTCTGTCATGTGGATGCCCCAGGCCAGCAGGAAGGTGCACCCTCTTT
CCCAACAGGGTATCAGTACCCCACAATGGATGAGCTGGCTGAAATGCTGCCTCCTGTTCTTACCCACCTAAGCCTGAAAAGCATCATTGG
AATTGGAGTTGGAGCTGGAGCTTACATCCTCAGCAGATTTGCACTCAACCATCCAGAGCTTGTGGAAGGCCTTGTGCTCATTAATGTTGA
CCCTTGCGCTAAAGGCTGGATTGACTGGGCAGCTTCCAAACTCTCTGGCCTGACAACCAATGTTGTGGACATTATTTTGGCTCATCACTT
TGGGCAGGAAGAGTTACAGGCCAACCTGGACCTGATCCAAACCTACAGAATGCATATTGCCCAAGACATCAACCAAGACAACCTGCAGCT
CTTCTTGAATTCCTACAATGGACGCAGAGACCTGGAGATCGAAAGACCCATACTGGGCCAAAATGATAACAAATCAAAAACATTAAAGTG
TTCTACTTTACTGGTGGTAGGGGACAATTCGCCTGCAGTTGAGGCTGTGGTCGAATGCAATTCCCGCCTGAACCCTATAAATACAACTTT
GCTAAAGATGGCGGACTGTGGGGGACTGCCCCAGGTAGTTCAGCCTGGGAAGCTCACCGAGGCCTTCAAGTACTTTTTGCAGGGAATGGG
CTACATCCCGTATGTGCAGCTCAGTCACCTGAGCACCGAGTCAGTACCATCTGCCAGCATGACTCGGCTCGCCCGATCACGAACCCACTC
AACCTCGAGTAGCCTCGGCTCTGGAGAAAGTCCCTTCAGCCGGTCTGTCACCAGCAATCAGTCAGATGGAACTCAAGAATCCTGTGAGTC
CCCTGATGTCCTGGACAGACACCAGACCATGGAGGTGTCCTGCTAAGCAGATGCTCCTCCCCTGGACCATTGCAAGTCCATCCTTCAAAT
GACCACTCCATAATATAACATTTCATCCAGTAAACTGGCCTCTACTATCTTTAACTCATGCATGGCCACTGAACCTCTCTCTAGTAGCCT
GGATTTATCATTCTCTCTGCCTGCCCACCCCCTTTTTTGTATAGCCCAAGAACCACTTCCATGCCATACTGTAACATTCCAACATCTTTA
GCTGATCAGATCTCTCCATATCCTCTCTTGCCAGCTTTTTCCCGTGCTCCCCCAACTATGTATCAGATAAGATTCTTTGATCCCGACTCT
GTGTGTGCGAGCACGCGTGTCTGTGTTTGTGTGTGCATAGTTCTGTGGTTTTAGACACGCTTTCTTGTAGTGCTTCTGCAAAAAACAAAA
AAGGGACTTATTTTGCATTCTCAATGGTGTTTTTAAGGGAATTAGGCAGAACAGATTTCTAGGTTGGGTAGGCCACTGCATTCTCTTTTG
TTTGCAAATTGGTCAACAAAATTTGCAAAGTGATTTCAGGAGAGAGCAGCTTTGAGGAATGTGGAAAATCATAATTGCCGTCTGGACCAT
TGATTGATTGTGACCAGTAGCAGAAGGGTGCCTGTTACATAGAGAGGCTCCTTCTGTCCAAATGAATTTCTGTATACTCTTCTATAAATA
AAAGGGAGGAATATATTCTGCTGGAAGCCCATGAACCATCGCTGAGGTTCTGATACAACATAGAGTTTTTTCCAAGGAGTGAATGTGGTT
TAATTACTGGACTCTCTTAGCACAGGAAGGTGGAAACAAAATGCCAGGCCTCTGCTCTGAAGAGCAAAACTGCTGTCGCTGCAGTATCTG
ATACCAGACATCCACATATCCACAAGAAGTGCCTCTTAGGTCTGTGACAGAGAGTGTGTCTCCATTCCTCAGTTCCCAGAAAGGGGAGAG
GTTTGGCCTAAAAAGCATGTAGATGGGGGAGAAATGGGTGGGGGGAGAGGAACAGCCATTAACACAGTATCATGTTTAACAAGTATAGCC
TTGATTTCAGTAGATGTAATGGAAGCCAAATTAAATTGATACAGAACCCATTTCTCAGAGTCTTTTTTTTTTTTTGAGACAGAGTCTCGC
TGTTACCCAGGCTGGAGTGCAATGGCGCAAACTTGGCTCACTGCAACCTCTGCCCCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCC
GAGTAGCTGAGACTACAGGCACCTGCCACCATACCCAGCTAAGTTATGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAGGCTG
GTCTCAAACTCCTGACCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGTCATTGCTCCCAGCCATTAG
AAAGATTGTTAATCCTATGAACTCCCTTTTGTAGGAGAGAAAGGGCCAATCTGTAGGGGTAGCCCTGTCCAGGTAAAGTTGTTTTCAGCC
TCATGTCTACTGTTAGGTGAGGGAGTCACAGCCAGACAGAGAGTATTGCTGGAGGGTGAGAGAATTGTGGAGACCAACTACCACATAGCA
AGAGCCCAGCTCTTGGGAGCATTGAGATGTAAGCTCAGGGTTACACAGTTCCAAATCTTGGGAAGGGGCTTTTCAGACAGACTGTTTGCT
TTCTGCTGAGATAAGGAATGCATCACTCTGCCAGAGTATGACTTTTTACAGATTATTAAATAAAGCTGCATATGTCTCATTGTTACCTGA

>72728_72728_4_RBL1-NDRG3_RBL1_chr20_35651053_ENST00000373664_NDRG3_chr20_35335410_ENST00000373803_length(amino acids)=1222AA_BP=0
MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI
LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL
FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY
FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE
KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP
GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV
IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG
SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI
PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL
DVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVILTYHDIGLN
HKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVE
GLVLINVDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIERPILGQND
NKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPYVQLSHLSTESVPSASMTR

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Fusion Gene PPI Analysis for RBL1-NDRG3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for RBL1-NDRG3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for RBL1-NDRG3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source