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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RBM28-AOAH (FusionGDB2 ID:72842)

Fusion Gene Summary for RBM28-AOAH

check button Fusion gene summary
Fusion gene informationFusion gene name: RBM28-AOAH
Fusion gene ID: 72842
HgeneTgene
Gene symbol

RBM28

AOAH

Gene ID

55131

313

Gene nameRNA binding motif protein 28acyloxyacyl hydrolase
SynonymsANES-
Cytomap

7q32.1

7p14.2

Type of geneprotein-codingprotein-coding
DescriptionRNA-binding protein 282810480G15Rikacyloxyacyl hydrolaseacyloxyacyl hydrolase (neutrophil)
Modification date2020031320200313
UniProtAcc.

P28039

Ensembl transtripts involved in fusion geneENST00000223073, ENST00000415472, 
ENST00000481788, 		ENST00000491444, 
ENST00000258749, ENST00000431169, 
ENST00000535891, ENST00000538464, 
Fusion gene scores* DoF score4 X 6 X 4=968 X 8 X 5=320
# samples 58
** MAII scorelog2(5/96*10)=-0.941106310946431
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/320*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RBM28 [Title/Abstract] AND AOAH [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRBM28(127957712)-AOAH(36634036), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneAOAH

GO:0006631

fatty acid metabolic process

1883828|29343645

TgeneAOAH

GO:0009104

lipopolysaccharide catabolic process

1883828|29343645


check buttonFusion gene breakpoints across RBM28 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AOAH (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4THCATCGA-CE-A484-01ARBM28chr7

127957712

-AOAHchr7

36634036

-


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Fusion Gene ORF analysis for RBM28-AOAH

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000223073ENST00000491444RBM28chr7

127957712

-AOAHchr7

36634036

-
5CDS-intronENST00000415472ENST00000491444RBM28chr7

127957712

-AOAHchr7

36634036

-
In-frameENST00000223073ENST00000258749RBM28chr7

127957712

-AOAHchr7

36634036

-
In-frameENST00000223073ENST00000431169RBM28chr7

127957712

-AOAHchr7

36634036

-
In-frameENST00000223073ENST00000535891RBM28chr7

127957712

-AOAHchr7

36634036

-
In-frameENST00000223073ENST00000538464RBM28chr7

127957712

-AOAHchr7

36634036

-
In-frameENST00000415472ENST00000258749RBM28chr7

127957712

-AOAHchr7

36634036

-
In-frameENST00000415472ENST00000431169RBM28chr7

127957712

-AOAHchr7

36634036

-
In-frameENST00000415472ENST00000535891RBM28chr7

127957712

-AOAHchr7

36634036

-
In-frameENST00000415472ENST00000538464RBM28chr7

127957712

-AOAHchr7

36634036

-
intron-3CDSENST00000481788ENST00000258749RBM28chr7

127957712

-AOAHchr7

36634036

-
intron-3CDSENST00000481788ENST00000431169RBM28chr7

127957712

-AOAHchr7

36634036

-
intron-3CDSENST00000481788ENST00000535891RBM28chr7

127957712

-AOAHchr7

36634036

-
intron-3CDSENST00000481788ENST00000538464RBM28chr7

127957712

-AOAHchr7

36634036

-
intron-intronENST00000481788ENST00000491444RBM28chr7

127957712

-AOAHchr7

36634036

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000223073RBM28chr7127957712-ENST00000535891AOAHchr736634036-308619031152784889
ENST00000223073RBM28chr7127957712-ENST00000258749AOAHchr736634036-303619031152784889
ENST00000223073RBM28chr7127957712-ENST00000431169AOAHchr736634036-315219031153048977
ENST00000223073RBM28chr7127957712-ENST00000538464AOAHchr736634036-318719031152784889
ENST00000415472RBM28chr7127957712-ENST00000535891AOAHchr736634036-26251442772323748
ENST00000415472RBM28chr7127957712-ENST00000258749AOAHchr736634036-25751442772323748
ENST00000415472RBM28chr7127957712-ENST00000431169AOAHchr736634036-26911442772587836
ENST00000415472RBM28chr7127957712-ENST00000538464AOAHchr736634036-27261442772323748

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000223073ENST00000535891RBM28chr7127957712-AOAHchr736634036-0.001233250.9987668
ENST00000223073ENST00000258749RBM28chr7127957712-AOAHchr736634036-0.0014001130.99859995
ENST00000223073ENST00000431169RBM28chr7127957712-AOAHchr736634036-0.0011214560.99887854
ENST00000223073ENST00000538464RBM28chr7127957712-AOAHchr736634036-0.0010150650.9989849
ENST00000415472ENST00000535891RBM28chr7127957712-AOAHchr736634036-0.0033179460.996682
ENST00000415472ENST00000258749RBM28chr7127957712-AOAHchr736634036-0.0036648890.99633515
ENST00000415472ENST00000431169RBM28chr7127957712-AOAHchr736634036-0.0037385060.9962614
ENST00000415472ENST00000538464RBM28chr7127957712-AOAHchr736634036-0.002698280.9973017

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Fusion Genomic Features for RBM28-AOAH


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RBM28-AOAH


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:127957712/chr7:36634036)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AOAH

P28039

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (PubMed:1883828, PubMed:8089145, PubMed:29343645). By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses (By similarity). In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria (By similarity). {ECO:0000250|UniProtKB:O35298, ECO:0000269|PubMed:1883828, ECO:0000269|PubMed:29343645, ECO:0000269|PubMed:8089145}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRBM28chr7:127957712chr7:36634036ENST00000223073-1619224_258596760.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneRBM28chr7:127957712chr7:36634036ENST00000415472-1215224_258455619.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneRBM28chr7:127957712chr7:36634036ENST00000223073-1619114_191596760.0DomainRRM 2
HgeneRBM28chr7:127957712chr7:36634036ENST00000223073-1619335_419596760.0DomainRRM 3
HgeneRBM28chr7:127957712chr7:36634036ENST00000223073-1619487_597596760.0DomainRRM 4
HgeneRBM28chr7:127957712chr7:36634036ENST00000223073-16194_80596760.0DomainRRM 1
HgeneRBM28chr7:127957712chr7:36634036ENST00000415472-1215114_191455619.0DomainRRM 2
HgeneRBM28chr7:127957712chr7:36634036ENST00000415472-1215335_419455619.0DomainRRM 3
HgeneRBM28chr7:127957712chr7:36634036ENST00000415472-12154_80455619.0DomainRRM 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRBM28chr7:127957712chr7:36634036ENST00000415472-1215487_597455619.0DomainRRM 4
TgeneAOAHchr7:127957712chr7:36634036ENST00000258749102137_118282576.0DomainSaposin B-type
TgeneAOAHchr7:127957712chr7:36634036ENST0000053589192037_118250544.0DomainSaposin B-type
TgeneAOAHchr7:127957712chr7:36634036ENST000002587491021173_177282576.0RegionLipopolysaccharide binding
TgeneAOAHchr7:127957712chr7:36634036ENST00000258749102138_70282576.0RegionImportant for enzyme activity%2C localization to cytoplasmic vesicles%2C and protein stability
TgeneAOAHchr7:127957712chr7:36634036ENST00000535891920173_177250544.0RegionLipopolysaccharide binding
TgeneAOAHchr7:127957712chr7:36634036ENST0000053589192038_70250544.0RegionImportant for enzyme activity%2C localization to cytoplasmic vesicles%2C and protein stability


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Fusion Gene Sequence for RBM28-AOAH


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>72842_72842_1_RBM28-AOAH_RBM28_chr7_127957712_ENST00000223073_AOAH_chr7_36634036_ENST00000258749_length(transcript)=3036nt_BP=1903nt
ACTTCCGGAATCTCTCGGCGTGTGAGCTTGGTTGTCCTACCAAAGCCAGCGTTTCGGCTCGCGTGCGCCGGCCTAGTTTGCTCGCGTCCT
CACGCGCTTTGGGTTTCCCGGTCTCATGGCCGGCCTGACCTTATTTGTGGGCCGCCTCCCGCCCTCGGCCCGCAGTGAGCAGCTGGAGGA
ACTGTTCAGTCAGGTGGGGCCGGTGAAGCAGTGCTTCGTGGTGACTGAAAAAGGGAGTAAGGCATGTCGAGGCTTTGGCTATGTCACTTT
TTCAATGCTGGAAGATGTTCAGAGGGCCCTCAAGGAGATTACCACCTTTGAAGGTTGCAAGATCAACGTGACTGTTGCCAAGAAAAAACT
GAGGAACAAGACAAAGGAAAAGGGGAAAAATGAAAACTCAGAGTGCCCAAAGAAGGAGCCGAAGGCTAAAAAAGCCAAAGTGGCAGATAA
GAAAGCCAGATTAATTATTCGGAACCTGAGCTTTAAGTGTTCAGAAGATGACTTGAAGACAGTATTTGCTCAATTTGGAGCTGTCCTGGA
AGTAAATATCCCTAGGAAACCAGATGGGAAGATGCGCGGTTTTGGTTTTGTTCAGTTCAAAAACCTCCTAGAAGCAGGTAAAGCTCTCAA
AGGCATGAACATGAAAGAGATAAAAGGCCGGACAGTGGCTGTGGATTGGGCCGTGGCAAAGGATAAATATAAAGATACACAGTCTGTTTC
TGCTATAGGTGAGGAAAAGAGCCATGAATCTAAACATCAGGAATCAGTTAAAAAGAAGGGCAGAGAGGAAGAGGATATGGAAGAGGAAGA
AAACGATGATGATGACGATGATGATGATGAAGAAGATGGGGTTTTTGATGATGAAGATGAAGAGGAAGAGAATATAGAATCAAAGGTGAC
CAAGCCTGTGCAAATTCAGAAGAGAGCAGTCAAGAGACCAGCCCCTGCAAAAAGCAGTGATCATTCTGAGGAGGACAGTGACCTAGAGGA
AAGCGATAGTATTGATGATGGAGAGGAACTGGCTCAGAGTGATACCAGCACTGAGGAGCAAGAGGATAAAGCTGTGCAAGTCTCAAACAA
AAAGAAGAGGAAATTACCCTCTGATGTGAATGAAGGGAAAACTGTTTTTATCAGAAATCTGTCCTTTGACTCAGAAGAAGAAGAACTTGG
GGAGCTTCTCCAACAGTTTGGAGAACTCAAATATGTCCGCATTGTCTTGCATCCAGACACAGAGCATTCTAAAGGTTGTGCATTTGCCCA
GTTCATGACTCAAGAAGCAGCTCAGAAATGCCTTCTAGCTGCTTCTCCAGAGAATGAGGCTGGTGGGCTTAAACTGGATGGCCGGCAGCT
CAAGGTTGACTTGGCGGTGACCCGTGATGAGGCTGCAAAGCTTCAGACGACGAAGGTGAAGAAGCCGACTGGCACCCGGAATCTCTATCT
GGCCCGAGAAGGCTTGATTCGTGCTGGGACGAAGGCTGCAGAGGGTGTGAGTGCTGCTGATATGGCCAAAAGAGAACGGTTTGAGCTGCT
GAAGCATCAGAAACTCAAGGACCAGAATATCTTTGTCTCCCGAACCAGGCTCTGCCTGCACAATCTCCCAAAGGCTGTAGATGACAAACA
GCTCAGAAAGCTGCTGCTGAGTGCTACTAGTGGAGAGAAAGGGGTGCGCATCAAGGAGTGTAGAGTGATGCGAGACCTCAAAGGAGTTCA
TGGGAACATGAAGGGTCAGTCCCTGGGCTACGCCTTTGCGGAGTTCCAAGAGCACGAGCATGCCCTGAAAGCCCTCCGCCTCATCAACAA
CAATCCAGAAATCTTTGGGCCTCTGAAGAGACCAATAGTGGAGTTCTCTTTAGAAGATCGAAGAAAACTTAAAATGAAGGAATTAAGGAT
CCAGCGCAGCTTGAACTCTTTCATCAATCTACCAACAGCCCTTACCAACGAGCTTGACTGGCCCCAACTCTCTGGTGCTACAGGATTTCT
GGACTCCACTGTTGGAATTAAAGAAAAATCTATTTACCTTCGCTTATGGAAAAGAAACCACTGTAATCACAGGGACTACCAGAATATTTC
AAGAAATGGTGCATCTTCCCGAAACCTGAAGAAATTTATAGAAAGCTTGTCTAGAAACAAGGTGTTGGACTATCCCGCCATCGTTATATA
TGCCATGATTGGAAATGATGTCTGCAGTGGGAAGAGTGACCCAGTCCCAGCCATGACCACTCCTGAGAAACTCTACTCCAACGTCATGCA
GACTCTGAAGCATCTAAATTCCCACCTGCCCAATGGCAGCCATGTTATTTTGTATGGCTTACCAGATGGAACCTTTCTCTGGGATAATTT
GCACAACAGATATCATCCTCTCGGCCAGCTAAATAAAGACATGACCTATGCGCAGTTGTACTCCTTCCTGAACTGCCTCCAGGTCAGCCC
CTGCCACGGCTGGATGTCTTCCAACAAGACGTTGCGGACTCTCACTTCAGAGAGAGCAGAGCAACTCTCCAACACACTGAAAAAAATTGC
AGCCAGTGAGAAATTTACAAACTTCAATCTTTTCTACATGGATTTTGCCTTCCATGAAATCATACAGGAGTGGCAGAAGAGAGGCGGACA
GCCCTGGCAGCTCATCGAGCCCGTGGATGGATTCCACCCCAACGAGGTGGCTTTGCTGTTGTTGGCGGATCATTTCTGGAAAAAGGTGCA
GCTCCAGTGGCCCCAAATCCTGGGAAAGGAGAATCCGTTCAACCCCCAGATTAAACAGGTGTTTGGAGACCAAGGCGGGCACTGAGCCTC
TCAGGAGCATGCACCCCTGGGGAGCACAGGGAGGCAGAGGCTTGGGTAAACTCATTCCACAACCCTATGGGGGCTGCCACGTCACAGGCC
CAAAGGACTCTTCTTCAGCAGCATCTTTGCAAATGTCTTTCTCTCAATGAAGAGCATATCTGGACGACTGTGCAATGCTGTGTGCTCCCG

>72842_72842_1_RBM28-AOAH_RBM28_chr7_127957712_ENST00000223073_AOAH_chr7_36634036_ENST00000258749_length(amino acids)=889AA_BP=596
MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEITTFEGCKINVTVAKKKLRNKTKEKG
KNENSECPKKEPKAKKAKVADKKARLIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLLEAGKALKGMNMKEIK
GRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEENDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKR
AVKRPAPAKSSDHSEEDSDLEESDSIDDGEELAQSDTSTEEQEDKAVQVSNKKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGE
LKYVRIVLHPDTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGGLKLDGRQLKVDLAVTRDEAAKLQTTKVKKPTGTRNLYLAREGLIRA
GTKAAEGVSAADMAKRERFELLKHQKLKDQNIFVSRTRLCLHNLPKAVDDKQLRKLLLSATSGEKGVRIKECRVMRDLKGVHGNMKGQSL
GYAFAEFQEHEHALKALRLINNNPEIFGPLKRPIVEFSLEDRRKLKMKELRIQRSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKE
KSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSH
LPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNF

--------------------------------------------------------------
>72842_72842_2_RBM28-AOAH_RBM28_chr7_127957712_ENST00000223073_AOAH_chr7_36634036_ENST00000431169_length(transcript)=3152nt_BP=1903nt
ACTTCCGGAATCTCTCGGCGTGTGAGCTTGGTTGTCCTACCAAAGCCAGCGTTTCGGCTCGCGTGCGCCGGCCTAGTTTGCTCGCGTCCT
CACGCGCTTTGGGTTTCCCGGTCTCATGGCCGGCCTGACCTTATTTGTGGGCCGCCTCCCGCCCTCGGCCCGCAGTGAGCAGCTGGAGGA
ACTGTTCAGTCAGGTGGGGCCGGTGAAGCAGTGCTTCGTGGTGACTGAAAAAGGGAGTAAGGCATGTCGAGGCTTTGGCTATGTCACTTT
TTCAATGCTGGAAGATGTTCAGAGGGCCCTCAAGGAGATTACCACCTTTGAAGGTTGCAAGATCAACGTGACTGTTGCCAAGAAAAAACT
GAGGAACAAGACAAAGGAAAAGGGGAAAAATGAAAACTCAGAGTGCCCAAAGAAGGAGCCGAAGGCTAAAAAAGCCAAAGTGGCAGATAA
GAAAGCCAGATTAATTATTCGGAACCTGAGCTTTAAGTGTTCAGAAGATGACTTGAAGACAGTATTTGCTCAATTTGGAGCTGTCCTGGA
AGTAAATATCCCTAGGAAACCAGATGGGAAGATGCGCGGTTTTGGTTTTGTTCAGTTCAAAAACCTCCTAGAAGCAGGTAAAGCTCTCAA
AGGCATGAACATGAAAGAGATAAAAGGCCGGACAGTGGCTGTGGATTGGGCCGTGGCAAAGGATAAATATAAAGATACACAGTCTGTTTC
TGCTATAGGTGAGGAAAAGAGCCATGAATCTAAACATCAGGAATCAGTTAAAAAGAAGGGCAGAGAGGAAGAGGATATGGAAGAGGAAGA
AAACGATGATGATGACGATGATGATGATGAAGAAGATGGGGTTTTTGATGATGAAGATGAAGAGGAAGAGAATATAGAATCAAAGGTGAC
CAAGCCTGTGCAAATTCAGAAGAGAGCAGTCAAGAGACCAGCCCCTGCAAAAAGCAGTGATCATTCTGAGGAGGACAGTGACCTAGAGGA
AAGCGATAGTATTGATGATGGAGAGGAACTGGCTCAGAGTGATACCAGCACTGAGGAGCAAGAGGATAAAGCTGTGCAAGTCTCAAACAA
AAAGAAGAGGAAATTACCCTCTGATGTGAATGAAGGGAAAACTGTTTTTATCAGAAATCTGTCCTTTGACTCAGAAGAAGAAGAACTTGG
GGAGCTTCTCCAACAGTTTGGAGAACTCAAATATGTCCGCATTGTCTTGCATCCAGACACAGAGCATTCTAAAGGTTGTGCATTTGCCCA
GTTCATGACTCAAGAAGCAGCTCAGAAATGCCTTCTAGCTGCTTCTCCAGAGAATGAGGCTGGTGGGCTTAAACTGGATGGCCGGCAGCT
CAAGGTTGACTTGGCGGTGACCCGTGATGAGGCTGCAAAGCTTCAGACGACGAAGGTGAAGAAGCCGACTGGCACCCGGAATCTCTATCT
GGCCCGAGAAGGCTTGATTCGTGCTGGGACGAAGGCTGCAGAGGGTGTGAGTGCTGCTGATATGGCCAAAAGAGAACGGTTTGAGCTGCT
GAAGCATCAGAAACTCAAGGACCAGAATATCTTTGTCTCCCGAACCAGGCTCTGCCTGCACAATCTCCCAAAGGCTGTAGATGACAAACA
GCTCAGAAAGCTGCTGCTGAGTGCTACTAGTGGAGAGAAAGGGGTGCGCATCAAGGAGTGTAGAGTGATGCGAGACCTCAAAGGAGTTCA
TGGGAACATGAAGGGTCAGTCCCTGGGCTACGCCTTTGCGGAGTTCCAAGAGCACGAGCATGCCCTGAAAGCCCTCCGCCTCATCAACAA
CAATCCAGAAATCTTTGGGCCTCTGAAGAGACCAATAGTGGAGTTCTCTTTAGAAGATCGAAGAAAACTTAAAATGAAGGAATTAAGGAT
CCAGCGCAGCTTGAACTCTTTCATCAATCTACCAACAGCCCTTACCAACGAGCTTGACTGGCCCCAACTCTCTGGTGCTACAGGATTTCT
GGACTCCACTGTTGGAATTAAAGAAAAATCTATTTACCTTCGCTTATGGAAAAGAAACCACTGTAATCACAGGGACTACCAGAATATTTC
AAGAAATGGTGCATCTTCCCGAAACCTGAAGAAATTTATAGAAAGCTTGTCTAGAAACAAGGTGTTGGACTATCCCGCCATCGTTATATA
TGCCATGATTGGAAATGATGTCTGCAGTGGGAAGAGTGACCCAGTCCCAGCCATGACCACTCCTGAGAAACTCTACTCCAACGTCATGCA
GACTCTGAAGCATCTAAATTCCCACCTGCCCAATGGCAGCCATGTTATTTTGTATGGCTTACCAGATGGAACCTTTCTCTGGGATAATTT
GCACAACAGATATCATCCTCTCGGCCAGCTAAATAAAGACATGACCTATGCGCAGTTGTACTCCTTCCTGAACTGCCTCCAGGTCAGCCC
CTGCCACGGCTGGATGTCTTCCAACAAGACGTTGCGGACTCTCACTTCAGAGAGAGCAGAGCAACTCTCCAACACACTGAAAAAAATTGC
AGCCAGTGAGAAATTTACAAACTTCAATCTTTTCTACATGGATTTTGCCTTCCATGAAATCATACAGGAGTGGCAGAAGAGAGGCGGACA
GCCCTGGCAGCTCATCGAGCCCGTGGATGGATTCCACCCCAACGAGAGAAAGAGCATCCTCCTCAAAGGCATATTAATGACAAGCCAGAC
ACTGGACAACCAAGAATGGACCCAGCTAACATCATGGATAAAGGGAAACCTGACATGCGACAGCAGAACCAGAGAGTGGCTTTGCTGTTG
TTGGCGGATCATTTCTGGAAAAAGGTGCAGCTCCAGTGGCCCCAAATCCTGGGAAAGGAGAATCCGTTCAACCCCCAGATTAAACAGGTG
TTTGGAGACCAAGGCGGGCACTGAGCCTCTCAGGAGCATGCACCCCTGGGGAGCACAGGGAGGCAGAGGCTTGGGTAAACTCATTCCACA
ACCCTATGGGGGCTGCCACGTCACAGGCCCAAAGGACTCTTCTTCAGCAGCATCTTTGCAAATGTCTTTCTCTCAATGAAGAGCATATCT
GGACGACTGTGCAATGCTGTGTGCTCCCGGGATCAGTAACCCTTCCGCTGTTCCTGAAATAACCTTTCATAAAGTGCTTTGGGTGCCATT

>72842_72842_2_RBM28-AOAH_RBM28_chr7_127957712_ENST00000223073_AOAH_chr7_36634036_ENST00000431169_length(amino acids)=977AA_BP=596
MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEITTFEGCKINVTVAKKKLRNKTKEKG
KNENSECPKKEPKAKKAKVADKKARLIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLLEAGKALKGMNMKEIK
GRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEENDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKR
AVKRPAPAKSSDHSEEDSDLEESDSIDDGEELAQSDTSTEEQEDKAVQVSNKKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGE
LKYVRIVLHPDTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGGLKLDGRQLKVDLAVTRDEAAKLQTTKVKKPTGTRNLYLAREGLIRA
GTKAAEGVSAADMAKRERFELLKHQKLKDQNIFVSRTRLCLHNLPKAVDDKQLRKLLLSATSGEKGVRIKECRVMRDLKGVHGNMKGQSL
GYAFAEFQEHEHALKALRLINNNPEIFGPLKRPIVEFSLEDRRKLKMKELRIQRSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKE
KSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSH
LPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNF
NLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNERKSILLKGILMTSQTLDNQEWTQLTSWIKGNLTCDSRTREWLCCCWRIISGKR

--------------------------------------------------------------
>72842_72842_3_RBM28-AOAH_RBM28_chr7_127957712_ENST00000223073_AOAH_chr7_36634036_ENST00000535891_length(transcript)=3086nt_BP=1903nt
ACTTCCGGAATCTCTCGGCGTGTGAGCTTGGTTGTCCTACCAAAGCCAGCGTTTCGGCTCGCGTGCGCCGGCCTAGTTTGCTCGCGTCCT
CACGCGCTTTGGGTTTCCCGGTCTCATGGCCGGCCTGACCTTATTTGTGGGCCGCCTCCCGCCCTCGGCCCGCAGTGAGCAGCTGGAGGA
ACTGTTCAGTCAGGTGGGGCCGGTGAAGCAGTGCTTCGTGGTGACTGAAAAAGGGAGTAAGGCATGTCGAGGCTTTGGCTATGTCACTTT
TTCAATGCTGGAAGATGTTCAGAGGGCCCTCAAGGAGATTACCACCTTTGAAGGTTGCAAGATCAACGTGACTGTTGCCAAGAAAAAACT
GAGGAACAAGACAAAGGAAAAGGGGAAAAATGAAAACTCAGAGTGCCCAAAGAAGGAGCCGAAGGCTAAAAAAGCCAAAGTGGCAGATAA
GAAAGCCAGATTAATTATTCGGAACCTGAGCTTTAAGTGTTCAGAAGATGACTTGAAGACAGTATTTGCTCAATTTGGAGCTGTCCTGGA
AGTAAATATCCCTAGGAAACCAGATGGGAAGATGCGCGGTTTTGGTTTTGTTCAGTTCAAAAACCTCCTAGAAGCAGGTAAAGCTCTCAA
AGGCATGAACATGAAAGAGATAAAAGGCCGGACAGTGGCTGTGGATTGGGCCGTGGCAAAGGATAAATATAAAGATACACAGTCTGTTTC
TGCTATAGGTGAGGAAAAGAGCCATGAATCTAAACATCAGGAATCAGTTAAAAAGAAGGGCAGAGAGGAAGAGGATATGGAAGAGGAAGA
AAACGATGATGATGACGATGATGATGATGAAGAAGATGGGGTTTTTGATGATGAAGATGAAGAGGAAGAGAATATAGAATCAAAGGTGAC
CAAGCCTGTGCAAATTCAGAAGAGAGCAGTCAAGAGACCAGCCCCTGCAAAAAGCAGTGATCATTCTGAGGAGGACAGTGACCTAGAGGA
AAGCGATAGTATTGATGATGGAGAGGAACTGGCTCAGAGTGATACCAGCACTGAGGAGCAAGAGGATAAAGCTGTGCAAGTCTCAAACAA
AAAGAAGAGGAAATTACCCTCTGATGTGAATGAAGGGAAAACTGTTTTTATCAGAAATCTGTCCTTTGACTCAGAAGAAGAAGAACTTGG
GGAGCTTCTCCAACAGTTTGGAGAACTCAAATATGTCCGCATTGTCTTGCATCCAGACACAGAGCATTCTAAAGGTTGTGCATTTGCCCA
GTTCATGACTCAAGAAGCAGCTCAGAAATGCCTTCTAGCTGCTTCTCCAGAGAATGAGGCTGGTGGGCTTAAACTGGATGGCCGGCAGCT
CAAGGTTGACTTGGCGGTGACCCGTGATGAGGCTGCAAAGCTTCAGACGACGAAGGTGAAGAAGCCGACTGGCACCCGGAATCTCTATCT
GGCCCGAGAAGGCTTGATTCGTGCTGGGACGAAGGCTGCAGAGGGTGTGAGTGCTGCTGATATGGCCAAAAGAGAACGGTTTGAGCTGCT
GAAGCATCAGAAACTCAAGGACCAGAATATCTTTGTCTCCCGAACCAGGCTCTGCCTGCACAATCTCCCAAAGGCTGTAGATGACAAACA
GCTCAGAAAGCTGCTGCTGAGTGCTACTAGTGGAGAGAAAGGGGTGCGCATCAAGGAGTGTAGAGTGATGCGAGACCTCAAAGGAGTTCA
TGGGAACATGAAGGGTCAGTCCCTGGGCTACGCCTTTGCGGAGTTCCAAGAGCACGAGCATGCCCTGAAAGCCCTCCGCCTCATCAACAA
CAATCCAGAAATCTTTGGGCCTCTGAAGAGACCAATAGTGGAGTTCTCTTTAGAAGATCGAAGAAAACTTAAAATGAAGGAATTAAGGAT
CCAGCGCAGCTTGAACTCTTTCATCAATCTACCAACAGCCCTTACCAACGAGCTTGACTGGCCCCAACTCTCTGGTGCTACAGGATTTCT
GGACTCCACTGTTGGAATTAAAGAAAAATCTATTTACCTTCGCTTATGGAAAAGAAACCACTGTAATCACAGGGACTACCAGAATATTTC
AAGAAATGGTGCATCTTCCCGAAACCTGAAGAAATTTATAGAAAGCTTGTCTAGAAACAAGGTGTTGGACTATCCCGCCATCGTTATATA
TGCCATGATTGGAAATGATGTCTGCAGTGGGAAGAGTGACCCAGTCCCAGCCATGACCACTCCTGAGAAACTCTACTCCAACGTCATGCA
GACTCTGAAGCATCTAAATTCCCACCTGCCCAATGGCAGCCATGTTATTTTGTATGGCTTACCAGATGGAACCTTTCTCTGGGATAATTT
GCACAACAGATATCATCCTCTCGGCCAGCTAAATAAAGACATGACCTATGCGCAGTTGTACTCCTTCCTGAACTGCCTCCAGGTCAGCCC
CTGCCACGGCTGGATGTCTTCCAACAAGACGTTGCGGACTCTCACTTCAGAGAGAGCAGAGCAACTCTCCAACACACTGAAAAAAATTGC
AGCCAGTGAGAAATTTACAAACTTCAATCTTTTCTACATGGATTTTGCCTTCCATGAAATCATACAGGAGTGGCAGAAGAGAGGCGGACA
GCCCTGGCAGCTCATCGAGCCCGTGGATGGATTCCACCCCAACGAGGTGGCTTTGCTGTTGTTGGCGGATCATTTCTGGAAAAAGGTGCA
GCTCCAGTGGCCCCAAATCCTGGGAAAGGAGAATCCGTTCAACCCCCAGATTAAACAGGTGTTTGGAGACCAAGGCGGGCACTGAGCCTC
TCAGGAGCATGCACCCCTGGGGAGCACAGGGAGGCAGAGGCTTGGGTAAACTCATTCCACAACCCTATGGGGGCTGCCACGTCACAGGCC
CAAAGGACTCTTCTTCAGCAGCATCTTTGCAAATGTCTTTCTCTCAATGAAGAGCATATCTGGACGACTGTGCAATGCTGTGTGCTCCCG
GGATCAGTAACCCTTCCGCTGTTCCTGAAATAACCTTTCATAAAGTGCTTTGGGTGCCATTCCAAACAAGAGAGTATCTGTGCCCTTTAC

>72842_72842_3_RBM28-AOAH_RBM28_chr7_127957712_ENST00000223073_AOAH_chr7_36634036_ENST00000535891_length(amino acids)=889AA_BP=596
MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEITTFEGCKINVTVAKKKLRNKTKEKG
KNENSECPKKEPKAKKAKVADKKARLIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLLEAGKALKGMNMKEIK
GRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEENDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKR
AVKRPAPAKSSDHSEEDSDLEESDSIDDGEELAQSDTSTEEQEDKAVQVSNKKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGE
LKYVRIVLHPDTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGGLKLDGRQLKVDLAVTRDEAAKLQTTKVKKPTGTRNLYLAREGLIRA
GTKAAEGVSAADMAKRERFELLKHQKLKDQNIFVSRTRLCLHNLPKAVDDKQLRKLLLSATSGEKGVRIKECRVMRDLKGVHGNMKGQSL
GYAFAEFQEHEHALKALRLINNNPEIFGPLKRPIVEFSLEDRRKLKMKELRIQRSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKE
KSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSH
LPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNF

--------------------------------------------------------------
>72842_72842_4_RBM28-AOAH_RBM28_chr7_127957712_ENST00000223073_AOAH_chr7_36634036_ENST00000538464_length(transcript)=3187nt_BP=1903nt
ACTTCCGGAATCTCTCGGCGTGTGAGCTTGGTTGTCCTACCAAAGCCAGCGTTTCGGCTCGCGTGCGCCGGCCTAGTTTGCTCGCGTCCT
CACGCGCTTTGGGTTTCCCGGTCTCATGGCCGGCCTGACCTTATTTGTGGGCCGCCTCCCGCCCTCGGCCCGCAGTGAGCAGCTGGAGGA
ACTGTTCAGTCAGGTGGGGCCGGTGAAGCAGTGCTTCGTGGTGACTGAAAAAGGGAGTAAGGCATGTCGAGGCTTTGGCTATGTCACTTT
TTCAATGCTGGAAGATGTTCAGAGGGCCCTCAAGGAGATTACCACCTTTGAAGGTTGCAAGATCAACGTGACTGTTGCCAAGAAAAAACT
GAGGAACAAGACAAAGGAAAAGGGGAAAAATGAAAACTCAGAGTGCCCAAAGAAGGAGCCGAAGGCTAAAAAAGCCAAAGTGGCAGATAA
GAAAGCCAGATTAATTATTCGGAACCTGAGCTTTAAGTGTTCAGAAGATGACTTGAAGACAGTATTTGCTCAATTTGGAGCTGTCCTGGA
AGTAAATATCCCTAGGAAACCAGATGGGAAGATGCGCGGTTTTGGTTTTGTTCAGTTCAAAAACCTCCTAGAAGCAGGTAAAGCTCTCAA
AGGCATGAACATGAAAGAGATAAAAGGCCGGACAGTGGCTGTGGATTGGGCCGTGGCAAAGGATAAATATAAAGATACACAGTCTGTTTC
TGCTATAGGTGAGGAAAAGAGCCATGAATCTAAACATCAGGAATCAGTTAAAAAGAAGGGCAGAGAGGAAGAGGATATGGAAGAGGAAGA
AAACGATGATGATGACGATGATGATGATGAAGAAGATGGGGTTTTTGATGATGAAGATGAAGAGGAAGAGAATATAGAATCAAAGGTGAC
CAAGCCTGTGCAAATTCAGAAGAGAGCAGTCAAGAGACCAGCCCCTGCAAAAAGCAGTGATCATTCTGAGGAGGACAGTGACCTAGAGGA
AAGCGATAGTATTGATGATGGAGAGGAACTGGCTCAGAGTGATACCAGCACTGAGGAGCAAGAGGATAAAGCTGTGCAAGTCTCAAACAA
AAAGAAGAGGAAATTACCCTCTGATGTGAATGAAGGGAAAACTGTTTTTATCAGAAATCTGTCCTTTGACTCAGAAGAAGAAGAACTTGG
GGAGCTTCTCCAACAGTTTGGAGAACTCAAATATGTCCGCATTGTCTTGCATCCAGACACAGAGCATTCTAAAGGTTGTGCATTTGCCCA
GTTCATGACTCAAGAAGCAGCTCAGAAATGCCTTCTAGCTGCTTCTCCAGAGAATGAGGCTGGTGGGCTTAAACTGGATGGCCGGCAGCT
CAAGGTTGACTTGGCGGTGACCCGTGATGAGGCTGCAAAGCTTCAGACGACGAAGGTGAAGAAGCCGACTGGCACCCGGAATCTCTATCT
GGCCCGAGAAGGCTTGATTCGTGCTGGGACGAAGGCTGCAGAGGGTGTGAGTGCTGCTGATATGGCCAAAAGAGAACGGTTTGAGCTGCT
GAAGCATCAGAAACTCAAGGACCAGAATATCTTTGTCTCCCGAACCAGGCTCTGCCTGCACAATCTCCCAAAGGCTGTAGATGACAAACA
GCTCAGAAAGCTGCTGCTGAGTGCTACTAGTGGAGAGAAAGGGGTGCGCATCAAGGAGTGTAGAGTGATGCGAGACCTCAAAGGAGTTCA
TGGGAACATGAAGGGTCAGTCCCTGGGCTACGCCTTTGCGGAGTTCCAAGAGCACGAGCATGCCCTGAAAGCCCTCCGCCTCATCAACAA
CAATCCAGAAATCTTTGGGCCTCTGAAGAGACCAATAGTGGAGTTCTCTTTAGAAGATCGAAGAAAACTTAAAATGAAGGAATTAAGGAT
CCAGCGCAGCTTGAACTCTTTCATCAATCTACCAACAGCCCTTACCAACGAGCTTGACTGGCCCCAACTCTCTGGTGCTACAGGATTTCT
GGACTCCACTGTTGGAATTAAAGAAAAATCTATTTACCTTCGCTTATGGAAAAGAAACCACTGTAATCACAGGGACTACCAGAATATTTC
AAGAAATGGTGCATCTTCCCGAAACCTGAAGAAATTTATAGAAAGCTTGTCTAGAAACAAGGTGTTGGACTATCCCGCCATCGTTATATA
TGCCATGATTGGAAATGATGTCTGCAGTGGGAAGAGTGACCCAGTCCCAGCCATGACCACTCCTGAGAAACTCTACTCCAACGTCATGCA
GACTCTGAAGCATCTAAATTCCCACCTGCCCAATGGCAGCCATGTTATTTTGTATGGCTTACCAGATGGAACCTTTCTCTGGGATAATTT
GCACAACAGATATCATCCTCTCGGCCAGCTAAATAAAGACATGACCTATGCGCAGTTGTACTCCTTCCTGAACTGCCTCCAGGTCAGCCC
CTGCCACGGCTGGATGTCTTCCAACAAGACGTTGCGGACTCTCACTTCAGAGAGAGCAGAGCAACTCTCCAACACACTGAAAAAAATTGC
AGCCAGTGAGAAATTTACAAACTTCAATCTTTTCTACATGGATTTTGCCTTCCATGAAATCATACAGGAGTGGCAGAAGAGAGGCGGACA
GCCCTGGCAGCTCATCGAGCCCGTGGATGGATTCCACCCCAACGAGGTGGCTTTGCTGTTGTTGGCGGATCATTTCTGGAAAAAGGTGCA
GCTCCAGTGGCCCCAAATCCTGGGAAAGGAGAATCCGTTCAACCCCCAGATTAAACAGGTGTTTGGAGACCAAGGCGGGCACTGAGCCTC
TCAGGAGCATGCACCCCTGGGGAGCACAGGGAGGCAGAGGCTTGGGTAAACTCATTCCACAACCCTATGGGGGCTGCCACGTCACAGGCC
CAAAGGACTCTTCTTCAGCAGCATCTTTGCAAATGTCTTTCTCTCAATGAAGAGCATATCTGGACGACTGTGCAATGCTGTGTGCTCCCG
GGATCAGTAACCCTTCCGCTGTTCCTGAAATAACCTTTCATAAAGTGCTTTGGGTGCCATTCCAAACAAGAGAGTATCTGTGCCCTTTAC
AGCTAATTGTTCTAAAAGGAGTTTCTAAAAACACTTAAGTCCAGCGATGTTCAGCAATTTACCCAGGGTCTTGGCATGCCAGGGGACTGA

>72842_72842_4_RBM28-AOAH_RBM28_chr7_127957712_ENST00000223073_AOAH_chr7_36634036_ENST00000538464_length(amino acids)=889AA_BP=596
MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEITTFEGCKINVTVAKKKLRNKTKEKG
KNENSECPKKEPKAKKAKVADKKARLIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLLEAGKALKGMNMKEIK
GRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEENDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKR
AVKRPAPAKSSDHSEEDSDLEESDSIDDGEELAQSDTSTEEQEDKAVQVSNKKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGE
LKYVRIVLHPDTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGGLKLDGRQLKVDLAVTRDEAAKLQTTKVKKPTGTRNLYLAREGLIRA
GTKAAEGVSAADMAKRERFELLKHQKLKDQNIFVSRTRLCLHNLPKAVDDKQLRKLLLSATSGEKGVRIKECRVMRDLKGVHGNMKGQSL
GYAFAEFQEHEHALKALRLINNNPEIFGPLKRPIVEFSLEDRRKLKMKELRIQRSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKE
KSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSH
LPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNF

--------------------------------------------------------------
>72842_72842_5_RBM28-AOAH_RBM28_chr7_127957712_ENST00000415472_AOAH_chr7_36634036_ENST00000258749_length(transcript)=2575nt_BP=1442nt
ACCAAAGCCAGCGTTTCGGCTCGCGTGCGCCGGCCTAGTTTGCTCGCGTCCTCACGCGCTTTGGGTTTCCCGGTCTCATGGCCGGCCTGA
CCTTATTTGTGGGCCGCCTCCCGCCCTCGGCCCGCAGTGAGCAGCTGGAGGAACTGTTCAGTCAGGTGGGGCCGGTGAAGCAGTGCTTCG
TGGTGACTGAAAAAGGCCGGACAGTGGCTGTGGATTGGGCCGTGGCAAAGGATAAATATAAAGATACACAGTCTGTTTCTGCTATAGGTG
AGGAAAAGAGCCATGAATCTAAACATCAGGAATCAGTTAAAAAGAAGGGCAGAGAGGAAGAGGATATGGAAGAGGAAGAAAACGATGATG
ATGACGATGATGATGATGAAGAAGATGGGGTTTTTGATGATGAAGATGAAGAGGAAGAGAATATAGAATCAAAGGTGACCAAGCCTGTGC
AAATTCAGAAGAGAGCAGTCAAGAGACCAGCCCCTGCAAAAAGCAGTGATCATTCTGAGGAGGACAGTGACCTAGAGGAAAGCGATAGTA
TTGATGATGGAGAGGAACTGGCTCAGAGTGATACCAGCACTGAGGAGCAAGAGGATAAAGCTGTGCAAGTCTCAAACAAAAAGAAGAGGA
AATTACCCTCTGATGTGAATGAAGGGAAAACTGTTTTTATCAGAAATCTGTCCTTTGACTCAGAAGAAGAAGAACTTGGGGAGCTTCTCC
AACAGTTTGGAGAACTCAAATATGTCCGCATTGTCTTGCATCCAGACACAGAGCATTCTAAAGGTTGTGCATTTGCCCAGTTCATGACTC
AAGAAGCAGCTCAGAAATGCCTTCTAGCTGCTTCTCCAGAGAATGAGGCTGGTGGGCTTAAACTGGATGGCCGGCAGCTCAAGGTTGACT
TGGCGGTGACCCGTGATGAGGCTGCAAAGCTTCAGACGACGAAGGTGAAGAAGCCGACTGGCACCCGGAATCTCTATCTGGCCCGAGAAG
GCTTGATTCGTGCTGGGACGAAGGCTGCAGAGGGTGTGAGTGCTGCTGATATGGCCAAAAGAGAACGGTTTGAGCTGCTGAAGCATCAGA
AACTCAAGGACCAGAATATCTTTGTCTCCCGAACCAGGCTCTGCCTGCACAATCTCCCAAAGGCTGTAGATGACAAACAGCTCAGAAAGC
TGCTGCTGAGTGCTACTAGTGGAGAGAAAGGGGTGCGCATCAAGGAGTGTAGAGTGATGCGAGACCTCAAAGGAGTTCATGGGAACATGA
AGGGTCAGTCCCTGGGCTACGCCTTTGCGGAGTTCCAAGAGCACGAGCATGCCCTGAAAGCCCTCCGCCTCATCAACAACAATCCAGAAA
TCTTTGGGCCTCTGAAGAGACCAATAGTGGAGTTCTCTTTAGAAGATCGAAGAAAACTTAAAATGAAGGAATTAAGGATCCAGCGCAGCT
TGAACTCTTTCATCAATCTACCAACAGCCCTTACCAACGAGCTTGACTGGCCCCAACTCTCTGGTGCTACAGGATTTCTGGACTCCACTG
TTGGAATTAAAGAAAAATCTATTTACCTTCGCTTATGGAAAAGAAACCACTGTAATCACAGGGACTACCAGAATATTTCAAGAAATGGTG
CATCTTCCCGAAACCTGAAGAAATTTATAGAAAGCTTGTCTAGAAACAAGGTGTTGGACTATCCCGCCATCGTTATATATGCCATGATTG
GAAATGATGTCTGCAGTGGGAAGAGTGACCCAGTCCCAGCCATGACCACTCCTGAGAAACTCTACTCCAACGTCATGCAGACTCTGAAGC
ATCTAAATTCCCACCTGCCCAATGGCAGCCATGTTATTTTGTATGGCTTACCAGATGGAACCTTTCTCTGGGATAATTTGCACAACAGAT
ATCATCCTCTCGGCCAGCTAAATAAAGACATGACCTATGCGCAGTTGTACTCCTTCCTGAACTGCCTCCAGGTCAGCCCCTGCCACGGCT
GGATGTCTTCCAACAAGACGTTGCGGACTCTCACTTCAGAGAGAGCAGAGCAACTCTCCAACACACTGAAAAAAATTGCAGCCAGTGAGA
AATTTACAAACTTCAATCTTTTCTACATGGATTTTGCCTTCCATGAAATCATACAGGAGTGGCAGAAGAGAGGCGGACAGCCCTGGCAGC
TCATCGAGCCCGTGGATGGATTCCACCCCAACGAGGTGGCTTTGCTGTTGTTGGCGGATCATTTCTGGAAAAAGGTGCAGCTCCAGTGGC
CCCAAATCCTGGGAAAGGAGAATCCGTTCAACCCCCAGATTAAACAGGTGTTTGGAGACCAAGGCGGGCACTGAGCCTCTCAGGAGCATG
CACCCCTGGGGAGCACAGGGAGGCAGAGGCTTGGGTAAACTCATTCCACAACCCTATGGGGGCTGCCACGTCACAGGCCCAAAGGACTCT
TCTTCAGCAGCATCTTTGCAAATGTCTTTCTCTCAATGAAGAGCATATCTGGACGACTGTGCAATGCTGTGTGCTCCCGGGATCAGTAAC

>72842_72842_5_RBM28-AOAH_RBM28_chr7_127957712_ENST00000415472_AOAH_chr7_36634036_ENST00000258749_length(amino acids)=748AA_BP=455
MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEE
ENDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDSIDDGEELAQSDTSTEEQEDKAVQVSN
KKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLHPDTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGGLKLDGRQ
LKVDLAVTRDEAAKLQTTKVKKPTGTRNLYLAREGLIRAGTKAAEGVSAADMAKRERFELLKHQKLKDQNIFVSRTRLCLHNLPKAVDDK
QLRKLLLSATSGEKGVRIKECRVMRDLKGVHGNMKGQSLGYAFAEFQEHEHALKALRLINNNPEIFGPLKRPIVEFSLEDRRKLKMKELR
IQRSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVI
YAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVS
PCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKV

--------------------------------------------------------------
>72842_72842_6_RBM28-AOAH_RBM28_chr7_127957712_ENST00000415472_AOAH_chr7_36634036_ENST00000431169_length(transcript)=2691nt_BP=1442nt
ACCAAAGCCAGCGTTTCGGCTCGCGTGCGCCGGCCTAGTTTGCTCGCGTCCTCACGCGCTTTGGGTTTCCCGGTCTCATGGCCGGCCTGA
CCTTATTTGTGGGCCGCCTCCCGCCCTCGGCCCGCAGTGAGCAGCTGGAGGAACTGTTCAGTCAGGTGGGGCCGGTGAAGCAGTGCTTCG
TGGTGACTGAAAAAGGCCGGACAGTGGCTGTGGATTGGGCCGTGGCAAAGGATAAATATAAAGATACACAGTCTGTTTCTGCTATAGGTG
AGGAAAAGAGCCATGAATCTAAACATCAGGAATCAGTTAAAAAGAAGGGCAGAGAGGAAGAGGATATGGAAGAGGAAGAAAACGATGATG
ATGACGATGATGATGATGAAGAAGATGGGGTTTTTGATGATGAAGATGAAGAGGAAGAGAATATAGAATCAAAGGTGACCAAGCCTGTGC
AAATTCAGAAGAGAGCAGTCAAGAGACCAGCCCCTGCAAAAAGCAGTGATCATTCTGAGGAGGACAGTGACCTAGAGGAAAGCGATAGTA
TTGATGATGGAGAGGAACTGGCTCAGAGTGATACCAGCACTGAGGAGCAAGAGGATAAAGCTGTGCAAGTCTCAAACAAAAAGAAGAGGA
AATTACCCTCTGATGTGAATGAAGGGAAAACTGTTTTTATCAGAAATCTGTCCTTTGACTCAGAAGAAGAAGAACTTGGGGAGCTTCTCC
AACAGTTTGGAGAACTCAAATATGTCCGCATTGTCTTGCATCCAGACACAGAGCATTCTAAAGGTTGTGCATTTGCCCAGTTCATGACTC
AAGAAGCAGCTCAGAAATGCCTTCTAGCTGCTTCTCCAGAGAATGAGGCTGGTGGGCTTAAACTGGATGGCCGGCAGCTCAAGGTTGACT
TGGCGGTGACCCGTGATGAGGCTGCAAAGCTTCAGACGACGAAGGTGAAGAAGCCGACTGGCACCCGGAATCTCTATCTGGCCCGAGAAG
GCTTGATTCGTGCTGGGACGAAGGCTGCAGAGGGTGTGAGTGCTGCTGATATGGCCAAAAGAGAACGGTTTGAGCTGCTGAAGCATCAGA
AACTCAAGGACCAGAATATCTTTGTCTCCCGAACCAGGCTCTGCCTGCACAATCTCCCAAAGGCTGTAGATGACAAACAGCTCAGAAAGC
TGCTGCTGAGTGCTACTAGTGGAGAGAAAGGGGTGCGCATCAAGGAGTGTAGAGTGATGCGAGACCTCAAAGGAGTTCATGGGAACATGA
AGGGTCAGTCCCTGGGCTACGCCTTTGCGGAGTTCCAAGAGCACGAGCATGCCCTGAAAGCCCTCCGCCTCATCAACAACAATCCAGAAA
TCTTTGGGCCTCTGAAGAGACCAATAGTGGAGTTCTCTTTAGAAGATCGAAGAAAACTTAAAATGAAGGAATTAAGGATCCAGCGCAGCT
TGAACTCTTTCATCAATCTACCAACAGCCCTTACCAACGAGCTTGACTGGCCCCAACTCTCTGGTGCTACAGGATTTCTGGACTCCACTG
TTGGAATTAAAGAAAAATCTATTTACCTTCGCTTATGGAAAAGAAACCACTGTAATCACAGGGACTACCAGAATATTTCAAGAAATGGTG
CATCTTCCCGAAACCTGAAGAAATTTATAGAAAGCTTGTCTAGAAACAAGGTGTTGGACTATCCCGCCATCGTTATATATGCCATGATTG
GAAATGATGTCTGCAGTGGGAAGAGTGACCCAGTCCCAGCCATGACCACTCCTGAGAAACTCTACTCCAACGTCATGCAGACTCTGAAGC
ATCTAAATTCCCACCTGCCCAATGGCAGCCATGTTATTTTGTATGGCTTACCAGATGGAACCTTTCTCTGGGATAATTTGCACAACAGAT
ATCATCCTCTCGGCCAGCTAAATAAAGACATGACCTATGCGCAGTTGTACTCCTTCCTGAACTGCCTCCAGGTCAGCCCCTGCCACGGCT
GGATGTCTTCCAACAAGACGTTGCGGACTCTCACTTCAGAGAGAGCAGAGCAACTCTCCAACACACTGAAAAAAATTGCAGCCAGTGAGA
AATTTACAAACTTCAATCTTTTCTACATGGATTTTGCCTTCCATGAAATCATACAGGAGTGGCAGAAGAGAGGCGGACAGCCCTGGCAGC
TCATCGAGCCCGTGGATGGATTCCACCCCAACGAGAGAAAGAGCATCCTCCTCAAAGGCATATTAATGACAAGCCAGACACTGGACAACC
AAGAATGGACCCAGCTAACATCATGGATAAAGGGAAACCTGACATGCGACAGCAGAACCAGAGAGTGGCTTTGCTGTTGTTGGCGGATCA
TTTCTGGAAAAAGGTGCAGCTCCAGTGGCCCCAAATCCTGGGAAAGGAGAATCCGTTCAACCCCCAGATTAAACAGGTGTTTGGAGACCA
AGGCGGGCACTGAGCCTCTCAGGAGCATGCACCCCTGGGGAGCACAGGGAGGCAGAGGCTTGGGTAAACTCATTCCACAACCCTATGGGG
GCTGCCACGTCACAGGCCCAAAGGACTCTTCTTCAGCAGCATCTTTGCAAATGTCTTTCTCTCAATGAAGAGCATATCTGGACGACTGTG

>72842_72842_6_RBM28-AOAH_RBM28_chr7_127957712_ENST00000415472_AOAH_chr7_36634036_ENST00000431169_length(amino acids)=836AA_BP=455
MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEE
ENDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDSIDDGEELAQSDTSTEEQEDKAVQVSN
KKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLHPDTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGGLKLDGRQ
LKVDLAVTRDEAAKLQTTKVKKPTGTRNLYLAREGLIRAGTKAAEGVSAADMAKRERFELLKHQKLKDQNIFVSRTRLCLHNLPKAVDDK
QLRKLLLSATSGEKGVRIKECRVMRDLKGVHGNMKGQSLGYAFAEFQEHEHALKALRLINNNPEIFGPLKRPIVEFSLEDRRKLKMKELR
IQRSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVI
YAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVS
PCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNERKSILLKGILMTSQ
TLDNQEWTQLTSWIKGNLTCDSRTREWLCCCWRIISGKRCSSSGPKSWERRIRSTPRLNRCLETKAGTEPLRSMHPWGAQGGRGLGKLIP

--------------------------------------------------------------
>72842_72842_7_RBM28-AOAH_RBM28_chr7_127957712_ENST00000415472_AOAH_chr7_36634036_ENST00000535891_length(transcript)=2625nt_BP=1442nt
ACCAAAGCCAGCGTTTCGGCTCGCGTGCGCCGGCCTAGTTTGCTCGCGTCCTCACGCGCTTTGGGTTTCCCGGTCTCATGGCCGGCCTGA
CCTTATTTGTGGGCCGCCTCCCGCCCTCGGCCCGCAGTGAGCAGCTGGAGGAACTGTTCAGTCAGGTGGGGCCGGTGAAGCAGTGCTTCG
TGGTGACTGAAAAAGGCCGGACAGTGGCTGTGGATTGGGCCGTGGCAAAGGATAAATATAAAGATACACAGTCTGTTTCTGCTATAGGTG
AGGAAAAGAGCCATGAATCTAAACATCAGGAATCAGTTAAAAAGAAGGGCAGAGAGGAAGAGGATATGGAAGAGGAAGAAAACGATGATG
ATGACGATGATGATGATGAAGAAGATGGGGTTTTTGATGATGAAGATGAAGAGGAAGAGAATATAGAATCAAAGGTGACCAAGCCTGTGC
AAATTCAGAAGAGAGCAGTCAAGAGACCAGCCCCTGCAAAAAGCAGTGATCATTCTGAGGAGGACAGTGACCTAGAGGAAAGCGATAGTA
TTGATGATGGAGAGGAACTGGCTCAGAGTGATACCAGCACTGAGGAGCAAGAGGATAAAGCTGTGCAAGTCTCAAACAAAAAGAAGAGGA
AATTACCCTCTGATGTGAATGAAGGGAAAACTGTTTTTATCAGAAATCTGTCCTTTGACTCAGAAGAAGAAGAACTTGGGGAGCTTCTCC
AACAGTTTGGAGAACTCAAATATGTCCGCATTGTCTTGCATCCAGACACAGAGCATTCTAAAGGTTGTGCATTTGCCCAGTTCATGACTC
AAGAAGCAGCTCAGAAATGCCTTCTAGCTGCTTCTCCAGAGAATGAGGCTGGTGGGCTTAAACTGGATGGCCGGCAGCTCAAGGTTGACT
TGGCGGTGACCCGTGATGAGGCTGCAAAGCTTCAGACGACGAAGGTGAAGAAGCCGACTGGCACCCGGAATCTCTATCTGGCCCGAGAAG
GCTTGATTCGTGCTGGGACGAAGGCTGCAGAGGGTGTGAGTGCTGCTGATATGGCCAAAAGAGAACGGTTTGAGCTGCTGAAGCATCAGA
AACTCAAGGACCAGAATATCTTTGTCTCCCGAACCAGGCTCTGCCTGCACAATCTCCCAAAGGCTGTAGATGACAAACAGCTCAGAAAGC
TGCTGCTGAGTGCTACTAGTGGAGAGAAAGGGGTGCGCATCAAGGAGTGTAGAGTGATGCGAGACCTCAAAGGAGTTCATGGGAACATGA
AGGGTCAGTCCCTGGGCTACGCCTTTGCGGAGTTCCAAGAGCACGAGCATGCCCTGAAAGCCCTCCGCCTCATCAACAACAATCCAGAAA
TCTTTGGGCCTCTGAAGAGACCAATAGTGGAGTTCTCTTTAGAAGATCGAAGAAAACTTAAAATGAAGGAATTAAGGATCCAGCGCAGCT
TGAACTCTTTCATCAATCTACCAACAGCCCTTACCAACGAGCTTGACTGGCCCCAACTCTCTGGTGCTACAGGATTTCTGGACTCCACTG
TTGGAATTAAAGAAAAATCTATTTACCTTCGCTTATGGAAAAGAAACCACTGTAATCACAGGGACTACCAGAATATTTCAAGAAATGGTG
CATCTTCCCGAAACCTGAAGAAATTTATAGAAAGCTTGTCTAGAAACAAGGTGTTGGACTATCCCGCCATCGTTATATATGCCATGATTG
GAAATGATGTCTGCAGTGGGAAGAGTGACCCAGTCCCAGCCATGACCACTCCTGAGAAACTCTACTCCAACGTCATGCAGACTCTGAAGC
ATCTAAATTCCCACCTGCCCAATGGCAGCCATGTTATTTTGTATGGCTTACCAGATGGAACCTTTCTCTGGGATAATTTGCACAACAGAT
ATCATCCTCTCGGCCAGCTAAATAAAGACATGACCTATGCGCAGTTGTACTCCTTCCTGAACTGCCTCCAGGTCAGCCCCTGCCACGGCT
GGATGTCTTCCAACAAGACGTTGCGGACTCTCACTTCAGAGAGAGCAGAGCAACTCTCCAACACACTGAAAAAAATTGCAGCCAGTGAGA
AATTTACAAACTTCAATCTTTTCTACATGGATTTTGCCTTCCATGAAATCATACAGGAGTGGCAGAAGAGAGGCGGACAGCCCTGGCAGC
TCATCGAGCCCGTGGATGGATTCCACCCCAACGAGGTGGCTTTGCTGTTGTTGGCGGATCATTTCTGGAAAAAGGTGCAGCTCCAGTGGC
CCCAAATCCTGGGAAAGGAGAATCCGTTCAACCCCCAGATTAAACAGGTGTTTGGAGACCAAGGCGGGCACTGAGCCTCTCAGGAGCATG
CACCCCTGGGGAGCACAGGGAGGCAGAGGCTTGGGTAAACTCATTCCACAACCCTATGGGGGCTGCCACGTCACAGGCCCAAAGGACTCT
TCTTCAGCAGCATCTTTGCAAATGTCTTTCTCTCAATGAAGAGCATATCTGGACGACTGTGCAATGCTGTGTGCTCCCGGGATCAGTAAC
CCTTCCGCTGTTCCTGAAATAACCTTTCATAAAGTGCTTTGGGTGCCATTCCAAACAAGAGAGTATCTGTGCCCTTTACAGCTAATTGTT

>72842_72842_7_RBM28-AOAH_RBM28_chr7_127957712_ENST00000415472_AOAH_chr7_36634036_ENST00000535891_length(amino acids)=748AA_BP=455
MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEE
ENDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDSIDDGEELAQSDTSTEEQEDKAVQVSN
KKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLHPDTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGGLKLDGRQ
LKVDLAVTRDEAAKLQTTKVKKPTGTRNLYLAREGLIRAGTKAAEGVSAADMAKRERFELLKHQKLKDQNIFVSRTRLCLHNLPKAVDDK
QLRKLLLSATSGEKGVRIKECRVMRDLKGVHGNMKGQSLGYAFAEFQEHEHALKALRLINNNPEIFGPLKRPIVEFSLEDRRKLKMKELR
IQRSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVI
YAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVS
PCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKV

--------------------------------------------------------------
>72842_72842_8_RBM28-AOAH_RBM28_chr7_127957712_ENST00000415472_AOAH_chr7_36634036_ENST00000538464_length(transcript)=2726nt_BP=1442nt
ACCAAAGCCAGCGTTTCGGCTCGCGTGCGCCGGCCTAGTTTGCTCGCGTCCTCACGCGCTTTGGGTTTCCCGGTCTCATGGCCGGCCTGA
CCTTATTTGTGGGCCGCCTCCCGCCCTCGGCCCGCAGTGAGCAGCTGGAGGAACTGTTCAGTCAGGTGGGGCCGGTGAAGCAGTGCTTCG
TGGTGACTGAAAAAGGCCGGACAGTGGCTGTGGATTGGGCCGTGGCAAAGGATAAATATAAAGATACACAGTCTGTTTCTGCTATAGGTG
AGGAAAAGAGCCATGAATCTAAACATCAGGAATCAGTTAAAAAGAAGGGCAGAGAGGAAGAGGATATGGAAGAGGAAGAAAACGATGATG
ATGACGATGATGATGATGAAGAAGATGGGGTTTTTGATGATGAAGATGAAGAGGAAGAGAATATAGAATCAAAGGTGACCAAGCCTGTGC
AAATTCAGAAGAGAGCAGTCAAGAGACCAGCCCCTGCAAAAAGCAGTGATCATTCTGAGGAGGACAGTGACCTAGAGGAAAGCGATAGTA
TTGATGATGGAGAGGAACTGGCTCAGAGTGATACCAGCACTGAGGAGCAAGAGGATAAAGCTGTGCAAGTCTCAAACAAAAAGAAGAGGA
AATTACCCTCTGATGTGAATGAAGGGAAAACTGTTTTTATCAGAAATCTGTCCTTTGACTCAGAAGAAGAAGAACTTGGGGAGCTTCTCC
AACAGTTTGGAGAACTCAAATATGTCCGCATTGTCTTGCATCCAGACACAGAGCATTCTAAAGGTTGTGCATTTGCCCAGTTCATGACTC
AAGAAGCAGCTCAGAAATGCCTTCTAGCTGCTTCTCCAGAGAATGAGGCTGGTGGGCTTAAACTGGATGGCCGGCAGCTCAAGGTTGACT
TGGCGGTGACCCGTGATGAGGCTGCAAAGCTTCAGACGACGAAGGTGAAGAAGCCGACTGGCACCCGGAATCTCTATCTGGCCCGAGAAG
GCTTGATTCGTGCTGGGACGAAGGCTGCAGAGGGTGTGAGTGCTGCTGATATGGCCAAAAGAGAACGGTTTGAGCTGCTGAAGCATCAGA
AACTCAAGGACCAGAATATCTTTGTCTCCCGAACCAGGCTCTGCCTGCACAATCTCCCAAAGGCTGTAGATGACAAACAGCTCAGAAAGC
TGCTGCTGAGTGCTACTAGTGGAGAGAAAGGGGTGCGCATCAAGGAGTGTAGAGTGATGCGAGACCTCAAAGGAGTTCATGGGAACATGA
AGGGTCAGTCCCTGGGCTACGCCTTTGCGGAGTTCCAAGAGCACGAGCATGCCCTGAAAGCCCTCCGCCTCATCAACAACAATCCAGAAA
TCTTTGGGCCTCTGAAGAGACCAATAGTGGAGTTCTCTTTAGAAGATCGAAGAAAACTTAAAATGAAGGAATTAAGGATCCAGCGCAGCT
TGAACTCTTTCATCAATCTACCAACAGCCCTTACCAACGAGCTTGACTGGCCCCAACTCTCTGGTGCTACAGGATTTCTGGACTCCACTG
TTGGAATTAAAGAAAAATCTATTTACCTTCGCTTATGGAAAAGAAACCACTGTAATCACAGGGACTACCAGAATATTTCAAGAAATGGTG
CATCTTCCCGAAACCTGAAGAAATTTATAGAAAGCTTGTCTAGAAACAAGGTGTTGGACTATCCCGCCATCGTTATATATGCCATGATTG
GAAATGATGTCTGCAGTGGGAAGAGTGACCCAGTCCCAGCCATGACCACTCCTGAGAAACTCTACTCCAACGTCATGCAGACTCTGAAGC
ATCTAAATTCCCACCTGCCCAATGGCAGCCATGTTATTTTGTATGGCTTACCAGATGGAACCTTTCTCTGGGATAATTTGCACAACAGAT
ATCATCCTCTCGGCCAGCTAAATAAAGACATGACCTATGCGCAGTTGTACTCCTTCCTGAACTGCCTCCAGGTCAGCCCCTGCCACGGCT
GGATGTCTTCCAACAAGACGTTGCGGACTCTCACTTCAGAGAGAGCAGAGCAACTCTCCAACACACTGAAAAAAATTGCAGCCAGTGAGA
AATTTACAAACTTCAATCTTTTCTACATGGATTTTGCCTTCCATGAAATCATACAGGAGTGGCAGAAGAGAGGCGGACAGCCCTGGCAGC
TCATCGAGCCCGTGGATGGATTCCACCCCAACGAGGTGGCTTTGCTGTTGTTGGCGGATCATTTCTGGAAAAAGGTGCAGCTCCAGTGGC
CCCAAATCCTGGGAAAGGAGAATCCGTTCAACCCCCAGATTAAACAGGTGTTTGGAGACCAAGGCGGGCACTGAGCCTCTCAGGAGCATG
CACCCCTGGGGAGCACAGGGAGGCAGAGGCTTGGGTAAACTCATTCCACAACCCTATGGGGGCTGCCACGTCACAGGCCCAAAGGACTCT
TCTTCAGCAGCATCTTTGCAAATGTCTTTCTCTCAATGAAGAGCATATCTGGACGACTGTGCAATGCTGTGTGCTCCCGGGATCAGTAAC
CCTTCCGCTGTTCCTGAAATAACCTTTCATAAAGTGCTTTGGGTGCCATTCCAAACAAGAGAGTATCTGTGCCCTTTACAGCTAATTGTT
CTAAAAGGAGTTTCTAAAAACACTTAAGTCCAGCGATGTTCAGCAATTTACCCAGGGTCTTGGCATGCCAGGGGACTGATCCCCCCTGTG

>72842_72842_8_RBM28-AOAH_RBM28_chr7_127957712_ENST00000415472_AOAH_chr7_36634036_ENST00000538464_length(amino acids)=748AA_BP=455
MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEE
ENDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDSIDDGEELAQSDTSTEEQEDKAVQVSN
KKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLHPDTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGGLKLDGRQ
LKVDLAVTRDEAAKLQTTKVKKPTGTRNLYLAREGLIRAGTKAAEGVSAADMAKRERFELLKHQKLKDQNIFVSRTRLCLHNLPKAVDDK
QLRKLLLSATSGEKGVRIKECRVMRDLKGVHGNMKGQSLGYAFAEFQEHEHALKALRLINNNPEIFGPLKRPIVEFSLEDRRKLKMKELR
IQRSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVI
YAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVS
PCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RBM28-AOAH


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RBM28-AOAH


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RBM28-AOAH


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource