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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RBM38-FRMD4B (FusionGDB2 ID:72866)

Fusion Gene Summary for RBM38-FRMD4B

check button Fusion gene summary
Fusion gene informationFusion gene name: RBM38-FRMD4B
Fusion gene ID: 72866
HgeneTgene
Gene symbol

RBM38

FRMD4B

Gene ID

55544

23150

Gene nameRNA binding motif protein 38FERM domain containing 4B
SynonymsHSRNASEB|RNPC1|SEB4B|SEB4D|dJ800J21.26030440G05Rik|GRSP1
Cytomap

20q13.31

3p14.1

Type of geneprotein-codingprotein-coding
DescriptionRNA-binding protein 38CLL-associated antigen KW-5RNA-binding region (RNP1, RRM) containing 1RNA-binding region-containing protein 1ssDNA-binding protein SEB4FERM domain-containing protein 4BGRP1-binding protein GRSP1
Modification date2020031320200313
UniProtAcc.

Q9Y2L6

Ensembl transtripts involved in fusion geneENST00000356208, ENST00000371219, 
ENST00000440234, 
ENST00000478263, 
ENST00000497757, ENST00000398540, 
ENST00000542259, 
Fusion gene scores* DoF score11 X 5 X 6=33012 X 12 X 10=1440
# samples 1014
** MAII scorelog2(10/330*10)=-1.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(14/1440*10)=-3.36257007938471
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RBM38 [Title/Abstract] AND FRMD4B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRBM38(55968389)-FRMD4B(69267530), # samples:4
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRBM38

GO:0043484

regulation of RNA splicing

19285943


check buttonFusion gene breakpoints across RBM38 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FRMD4B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-L3-A524-01ARBM38chr20

55968388

+FRMD4Bchr3

69267529

-
ChimerDB4LUSCTCGA-L3-A524-01ARBM38chr20

55968389

-FRMD4Bchr3

69267530

-
ChimerDB4LUSCTCGA-L3-A524-01ARBM38chr20

55968389

+FRMD4Bchr3

69267530

-
ChimerDB4LUSCTCGA-L3-A524RBM38chr20

55968389

+FRMD4Bchr3

69267530

-


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Fusion Gene ORF analysis for RBM38-FRMD4B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000356208ENST00000478263RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
5CDS-intronENST00000356208ENST00000478263RBM38chr20

55968389

+FRMD4Bchr3

69267530

-
5CDS-intronENST00000356208ENST00000497757RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
5CDS-intronENST00000356208ENST00000497757RBM38chr20

55968389

+FRMD4Bchr3

69267530

-
5CDS-intronENST00000371219ENST00000478263RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
5CDS-intronENST00000371219ENST00000478263RBM38chr20

55968389

+FRMD4Bchr3

69267530

-
5CDS-intronENST00000371219ENST00000497757RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
5CDS-intronENST00000371219ENST00000497757RBM38chr20

55968389

+FRMD4Bchr3

69267530

-
In-frameENST00000356208ENST00000398540RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
In-frameENST00000356208ENST00000398540RBM38chr20

55968389

+FRMD4Bchr3

69267530

-
In-frameENST00000356208ENST00000542259RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
In-frameENST00000356208ENST00000542259RBM38chr20

55968389

+FRMD4Bchr3

69267530

-
In-frameENST00000371219ENST00000398540RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
In-frameENST00000371219ENST00000398540RBM38chr20

55968389

+FRMD4Bchr3

69267530

-
In-frameENST00000371219ENST00000542259RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
In-frameENST00000371219ENST00000542259RBM38chr20

55968389

+FRMD4Bchr3

69267530

-
intron-3CDSENST00000440234ENST00000398540RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
intron-3CDSENST00000440234ENST00000398540RBM38chr20

55968389

+FRMD4Bchr3

69267530

-
intron-3CDSENST00000440234ENST00000542259RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
intron-3CDSENST00000440234ENST00000542259RBM38chr20

55968389

+FRMD4Bchr3

69267530

-
intron-intronENST00000440234ENST00000478263RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
intron-intronENST00000440234ENST00000478263RBM38chr20

55968389

+FRMD4Bchr3

69267530

-
intron-intronENST00000440234ENST00000497757RBM38chr20

55968388

+FRMD4Bchr3

69267529

-
intron-intronENST00000440234ENST00000497757RBM38chr20

55968389

+FRMD4Bchr3

69267530

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000356208RBM38chr2055968389+ENST00000398540FRMD4Bchr369267530-4836591792964961
ENST00000356208RBM38chr2055968389+ENST00000542259FRMD4Bchr369267530-4831591792964961
ENST00000371219RBM38chr2055968389+ENST00000398540FRMD4Bchr369267530-46874421012815904
ENST00000371219RBM38chr2055968389+ENST00000542259FRMD4Bchr369267530-46824421012815904
ENST00000356208RBM38chr2055968388+ENST00000398540FRMD4Bchr369267529-4836591792964961
ENST00000356208RBM38chr2055968388+ENST00000542259FRMD4Bchr369267529-4831591792964961
ENST00000371219RBM38chr2055968388+ENST00000398540FRMD4Bchr369267529-46874421012815904
ENST00000371219RBM38chr2055968388+ENST00000542259FRMD4Bchr369267529-46824421012815904

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000356208ENST00000398540RBM38chr2055968389+FRMD4Bchr369267530-0.0003808230.9996191
ENST00000356208ENST00000542259RBM38chr2055968389+FRMD4Bchr369267530-0.0003793930.99962056
ENST00000371219ENST00000398540RBM38chr2055968389+FRMD4Bchr369267530-0.0006504680.99934953
ENST00000371219ENST00000542259RBM38chr2055968389+FRMD4Bchr369267530-0.0006485090.99935144
ENST00000356208ENST00000398540RBM38chr2055968388+FRMD4Bchr369267529-0.0003808230.9996191
ENST00000356208ENST00000542259RBM38chr2055968388+FRMD4Bchr369267529-0.0003793930.99962056
ENST00000371219ENST00000398540RBM38chr2055968388+FRMD4Bchr369267529-0.0006504680.99934953
ENST00000371219ENST00000542259RBM38chr2055968388+FRMD4Bchr369267529-0.0006485090.99935144

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Fusion Genomic Features for RBM38-FRMD4B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RBM38-FRMD4B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:55968389/chr3:69267530)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FRMD4B

Q9Y2L6

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization. {ECO:0000250|UniProtKB:Q920B0}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRBM38chr20:55968388chr3:69267529ENST00000356208+3434_111138240.0DomainRRM
HgeneRBM38chr20:55968389chr3:69267530ENST00000356208+3434_111138240.0DomainRRM
TgeneFRMD4Bchr20:55968388chr3:69267529ENST00000398540823417_4502431035.0Coiled coilOntology_term=ECO:0000255
TgeneFRMD4Bchr20:55968388chr3:69267529ENST00000398540823531_5612431035.0Coiled coilOntology_term=ECO:0000255
TgeneFRMD4Bchr20:55968389chr3:69267530ENST00000398540823417_4502431035.0Coiled coilOntology_term=ECO:0000255
TgeneFRMD4Bchr20:55968389chr3:69267530ENST00000398540823531_5612431035.0Coiled coilOntology_term=ECO:0000255
TgeneFRMD4Bchr20:55968388chr3:69267529ENST00000398540823542_9712431035.0RegionNecessary for adherens junction and tight junction localization
TgeneFRMD4Bchr20:55968389chr3:69267530ENST00000398540823542_9712431035.0RegionNecessary for adherens junction and tight junction localization

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRBM38chr20:55968388chr3:69267529ENST00000440234+1334_1110122.0DomainRRM
HgeneRBM38chr20:55968389chr3:69267530ENST00000440234+1334_1110122.0DomainRRM
TgeneFRMD4Bchr20:55968388chr3:69267529ENST0000039854082359_3612431035.0DomainFERM
TgeneFRMD4Bchr20:55968389chr3:69267530ENST0000039854082359_3612431035.0DomainFERM


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Fusion Gene Sequence for RBM38-FRMD4B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>72866_72866_1_RBM38-FRMD4B_RBM38_chr20_55968388_ENST00000356208_FRMD4B_chr3_69267529_ENST00000398540_length(transcript)=4836nt_BP=591nt
GCAGCGCCGGTCGGGAGCGCAGCGCGGCGCACGTCGGCGCGCACGGCGGGACGGGCGCCGGAGTGGTCGGGCCTGGCGGCTGGACGGGCG
CCCCTCGCTGCCCCGCGCGCTCCCCGCCGCCCCCCATGAGCGCAGCCCCGCGCGGCCCGGGTCCGTAGGCGGCGGGGCGCCCCCCATGCT
GCTGCAGCCCGCGCCGTGCGCCCCGAGCGCGGGCTTCCCGCGGCCCCTGGCCGCCCCCGGCGCCATGCACGGCTCGCAGAAGGACACCAC
GTTCACCAAGATCTTCGTGGGCGGCCTGCCGTACCACACTACCGACGCCTCGCTCAGGAAGTACTTCGAGGGCTTCGGCGACATCGAGGA
GGCCGTGGTCATCACCGACCGCCAGACGGGCAAGTCCCGCGGCTACGGCTTCGTGACCATGGCCGACCGGGCGGCAGCTGAGAGGGCTTG
CAAAGACCCGAACCCCATCATCGACGGCCGCAAGGCCAACGTGAACCTGGCATATCTGGGCGCCAAGCCGCGGAGCCTCCAGACGGGCTT
TGCCATTGGGGTGCAGCAGCTGCACCCCACCTTGATCCAGCGGACTTACGGGTATATGAAAATAGTAGAAGCTCTACCGACTTACGGTGT
CCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATAAGGGAATTGGCCAATATGATATACAAGACAA
GGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGAAAAAATTTGCTGTTGAAGTTCATGATCCACG
AAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGTATGCTAACTCTTCTCTCATCAAGTCCATTTG
GGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAATTCCTTCAGCCAGGAGTTTAGATGAGATTGC
AATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGAAAAGTCAGTTCATCATGGCAAGTAATGGCAG
TTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAATCCTTGAACTAAAGAAGAAGGAGAAACTATT
ACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTGAGCTCACAGGCAAAATGCCAAAGGAGTATCC
CCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAATTAGATGACAACTTGCTGCCGAGTGAAGAAGA
TCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTGCAAAGAAACTTGCCAATGAGCCAGACCTTTG
TAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGGAGATTGAAAATGCAATAAACGAATACCGAAT
TAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCTCAGAGAGTAGCTCTTTGTCTGACACCACCAC
CTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTCATTCTCCAAGAATTCTTCCCCCCAAGTCTCT
TGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCAGGCAGTCCAGAGAAATGCTGTCCACACACAG
CAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGCCAGTTCTTACCCGAAACGCCTACAGCAGCAG
CCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGTCCCAGTCCCACCTGCTCTCCGAGATGGACAG
CGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCGATGACGGGTCTTCTTATACAAGCCAATCAAG
CACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGGACACTCGCACCAGGGGTCGGAGGAGGTCAAA
GAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATAGTTTGAGGAATGGTGTTTACTCAAAGAGTCA
GGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACTTTTATTACAGTGGTGGTTATGTCTATGAGAA
TGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGATATGAGCGCCAGAGGGACTACAGCAGATCCTT
TCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAAGGAAGGCTGCTGCAAAATCGGAGCACATCAC
CAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCTCTGGGCAGAAGGATCAGGGACACAGCCCGCA
GACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAGTACCTTGTTCTCCAAGCAGTCGTGCATCCTC
GTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAGGGCTGTCGGATTACGAGACTCCAGCACATTC
TTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAATACACAGAAATCAGTCAACTGGATGGTACAGA
TGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAGATTCAAAGCCTGGAACATTAGTCTGAACTGC
AGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATTTGTCTTCCGAGAGGATGTTCGTTTTAGAAAC
CTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATCACACACCAAGCCCCACAAAGCCCCTAAAGGA
GGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGAAGTATTGCCAAGAGAGGACTCAGTGTGAAGC
CTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAAACATGAAAGGGCATTCAGGATGTCCCATGGC
AATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGAAGCTCCGGAGTCATTGCTCACTTCAGAGTTT
GAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGACAGTATTGGAAAATTACTTGAAGCTGGATTT
TCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTTCATAAGCACCATAAAATGGGTTCTGGAAAAA
CTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCAGCCCACTGAATAATTGACAAAGTCTGCTTGG
AGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTGATGAGCTATTGTTCTGGCTGTTAATTCTCCA
ACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTTGAAAAAGCATTTTAAGATGATACAGAAAGTA
TCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATGGTGAACGTTAGAAAATTAAACAAGTCTGGAT
TCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAAACAACAACAACGACAAAAAGCTCCAAGCTGC
AGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGCTATGGTTTATTGTAGGGTTTTGTTTGTTTGT
TTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAAAATTACATAAAAGGTGCTCCTTTCCCCCTTC
TTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGGAACATTTTCTATCTATATTCCAAAGCATGTA
ATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATGAAGTTTGGGAAAAAATTTTGGAAAAAAGACA
AGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAAATAACCTTTTTGCATATTCTTTTATTGTTCT
GACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGAAAATGTTTACGTTTTCTTCCATTTATGTCAG
GGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTTCGGATTTTTATTTATAGTATTACCGTATTTT
ATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTATTGATGGCATATTCTACTTGAATTGGCAGTT

>72866_72866_1_RBM38-FRMD4B_RBM38_chr20_55968388_ENST00000356208_FRMD4B_chr3_69267529_ENST00000398540_length(amino acids)=961AA_BP=171
MDGRPSLPRALPAAPHERSPARPGSVGGGAPPMLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFG
DIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGYMKIVEALP
TYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLI
KSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKK
EKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANE
PDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILP
PKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLESQSHLLS
EMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVY
SKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKS
EHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSDYET

--------------------------------------------------------------
>72866_72866_2_RBM38-FRMD4B_RBM38_chr20_55968388_ENST00000356208_FRMD4B_chr3_69267529_ENST00000542259_length(transcript)=4831nt_BP=591nt
GCAGCGCCGGTCGGGAGCGCAGCGCGGCGCACGTCGGCGCGCACGGCGGGACGGGCGCCGGAGTGGTCGGGCCTGGCGGCTGGACGGGCG
CCCCTCGCTGCCCCGCGCGCTCCCCGCCGCCCCCCATGAGCGCAGCCCCGCGCGGCCCGGGTCCGTAGGCGGCGGGGCGCCCCCCATGCT
GCTGCAGCCCGCGCCGTGCGCCCCGAGCGCGGGCTTCCCGCGGCCCCTGGCCGCCCCCGGCGCCATGCACGGCTCGCAGAAGGACACCAC
GTTCACCAAGATCTTCGTGGGCGGCCTGCCGTACCACACTACCGACGCCTCGCTCAGGAAGTACTTCGAGGGCTTCGGCGACATCGAGGA
GGCCGTGGTCATCACCGACCGCCAGACGGGCAAGTCCCGCGGCTACGGCTTCGTGACCATGGCCGACCGGGCGGCAGCTGAGAGGGCTTG
CAAAGACCCGAACCCCATCATCGACGGCCGCAAGGCCAACGTGAACCTGGCATATCTGGGCGCCAAGCCGCGGAGCCTCCAGACGGGCTT
TGCCATTGGGGTGCAGCAGCTGCACCCCACCTTGATCCAGCGGACTTACGGGTATATGAAAATAGTAGAAGCTCTACCGACTTACGGTGT
CCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATAAGGGAATTGGCCAATATGATATACAAGACAA
GGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGAAAAAATTTGCTGTTGAAGTTCATGATCCACG
AAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGTATGCTAACTCTTCTCTCATCAAGTCCATTTG
GGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAATTCCTTCAGCCAGGAGTTTAGATGAGATTGC
AATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGAAAAGTCAGTTCATCATGGCAAGTAATGGCAG
TTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAATCCTTGAACTAAAGAAGAAGGAGAAACTATT
ACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTGAGCTCACAGGCAAAATGCCAAAGGAGTATCC
CCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAATTAGATGACAACTTGCTGCCGAGTGAAGAAGA
TCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTGCAAAGAAACTTGCCAATGAGCCAGACCTTTG
TAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGGAGATTGAAAATGCAATAAACGAATACCGAAT
TAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCTCAGAGAGTAGCTCTTTGTCTGACACCACCAC
CTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTCATTCTCCAAGAATTCTTCCCCCCAAGTCTCT
TGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCAGGCAGTCCAGAGAAATGCTGTCCACACACAG
CAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGCCAGTTCTTACCCGAAACGCCTACAGCAGCAG
CCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGTCCCAGTCCCACCTGCTCTCCGAGATGGACAG
CGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCGATGACGGGTCTTCTTATACAAGCCAATCAAG
CACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGGACACTCGCACCAGGGGTCGGAGGAGGTCAAA
GAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATAGTTTGAGGAATGGTGTTTACTCAAAGAGTCA
GGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACTTTTATTACAGTGGTGGTTATGTCTATGAGAA
TGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGATATGAGCGCCAGAGGGACTACAGCAGATCCTT
TCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAAGGAAGGCTGCTGCAAAATCGGAGCACATCAC
CAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCTCTGGGCAGAAGGATCAGGGACACAGCCCGCA
GACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAGTACCTTGTTCTCCAAGCAGTCGTGCATCCTC
GTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAGGGCTGTCGGATTACGAGACTCCAGCACATTC
TTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAATACACAGAAATCAGTCAACTGGATGGTACAGA
TGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAGATTCAAAGCCTGGAACATTAGTCTGAACTGC
AGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATTTGTCTTCCGAGAGGATGTTCGTTTTAGAAAC
CTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATCACACACCAAGCCCCACAAAGCCCCTAAAGGA
GGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGAAGTATTGCCAAGAGAGGACTCAGTGTGAAGC
CTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAAACATGAAAGGGCATTCAGGATGTCCCATGGC
AATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGAAGCTCCGGAGTCATTGCTCACTTCAGAGTTT
GAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGACAGTATTGGAAAATTACTTGAAGCTGGATTT
TCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTTCATAAGCACCATAAAATGGGTTCTGGAAAAA
CTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCAGCCCACTGAATAATTGACAAAGTCTGCTTGG
AGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTGATGAGCTATTGTTCTGGCTGTTAATTCTCCA
ACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTTGAAAAAGCATTTTAAGATGATACAGAAAGTA
TCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATGGTGAACGTTAGAAAATTAAACAAGTCTGGAT
TCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAAACAACAACAACGACAAAAAGCTCCAAGCTGC
AGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGCTATGGTTTATTGTAGGGTTTTGTTTGTTTGT
TTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAAAATTACATAAAAGGTGCTCCTTTCCCCCTTC
TTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGGAACATTTTCTATCTATATTCCAAAGCATGTA
ATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATGAAGTTTGGGAAAAAATTTTGGAAAAAAGACA
AGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAAATAACCTTTTTGCATATTCTTTTATTGTTCT
GACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGAAAATGTTTACGTTTTCTTCCATTTATGTCAG
GGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTTCGGATTTTTATTTATAGTATTACCGTATTTT
ATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTATTGATGGCATATTCTACTTGAATTGGCAGTT

>72866_72866_2_RBM38-FRMD4B_RBM38_chr20_55968388_ENST00000356208_FRMD4B_chr3_69267529_ENST00000542259_length(amino acids)=961AA_BP=171
MDGRPSLPRALPAAPHERSPARPGSVGGGAPPMLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFG
DIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGYMKIVEALP
TYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLI
KSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKK
EKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANE
PDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILP
PKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLESQSHLLS
EMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVY
SKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKS
EHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSDYET

--------------------------------------------------------------
>72866_72866_3_RBM38-FRMD4B_RBM38_chr20_55968388_ENST00000371219_FRMD4B_chr3_69267529_ENST00000398540_length(transcript)=4687nt_BP=442nt
ATAAACATCAGCTTAAGTAAAAACGTCTTGAAGACACTTTCCTGCTTACCTTCCAAGCATAGCGTCGCAAACTCCTTCTCAGAGGAAAGT
CTCGGCCCTCACTGGTGGGCAAGTCCAGGCGGCCCCCCAAGCTCCCTTCGGGGTTCATTTTTGCCCTATCCCCGCAGGGGATTATTTTTG
TCCTTGAAGGCCACATTTCCCAGGCCTTGAACTTTGACGGGAGGAGCTGGAATCCAGGAGGCATCTTTGTGGGAGAGCCCCAGGTGACCA
TGGCCGACCGGGCGGCAGCTGAGAGGGCTTGCAAAGACCCGAACCCCATCATCGACGGCCGCAAGGCCAACGTGAACCTGGCATATCTGG
GCGCCAAGCCGCGGAGCCTCCAGACGGGCTTTGCCATTGGGGTGCAGCAGCTGCACCCCACCTTGATCCAGCGGACTTACGGGTATATGA
AAATAGTAGAAGCTCTACCGACTTACGGTGTCCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATA
AGGGAATTGGCCAATATGATATACAAGACAAGGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGA
AAAAATTTGCTGTTGAAGTTCATGATCCACGAAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGT
ATGCTAACTCTTCTCTCATCAAGTCCATTTGGGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAA
TTCCTTCAGCCAGGAGTTTAGATGAGATTGCAATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGA
AAAGTCAGTTCATCATGGCAAGTAATGGCAGTTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAA
TCCTTGAACTAAAGAAGAAGGAGAAACTATTACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTG
AGCTCACAGGCAAAATGCCAAAGGAGTATCCCCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAAT
TAGATGACAACTTGCTGCCGAGTGAAGAAGATCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTG
CAAAGAAACTTGCCAATGAGCCAGACCTTTGTAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGG
AGATTGAAAATGCAATAAACGAATACCGAATTAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCT
CAGAGAGTAGCTCTTTGTCTGACACCACCACCTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTC
ATTCTCCAAGAATTCTTCCCCCCAAGTCTCTTGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCA
GGCAGTCCAGAGAAATGCTGTCCACACACAGCAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGC
CAGTTCTTACCCGAAACGCCTACAGCAGCAGCCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGT
CCCAGTCCCACCTGCTCTCCGAGATGGACAGCGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCG
ATGACGGGTCTTCTTATACAAGCCAATCAAGCACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGG
ACACTCGCACCAGGGGTCGGAGGAGGTCAAAGAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATA
GTTTGAGGAATGGTGTTTACTCAAAGAGTCAGGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACT
TTTATTACAGTGGTGGTTATGTCTATGAGAATGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGAT
ATGAGCGCCAGAGGGACTACAGCAGATCCTTTCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAA
GGAAGGCTGCTGCAAAATCGGAGCACATCACCAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCT
CTGGGCAGAAGGATCAGGGACACAGCCCGCAGACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAG
TACCTTGTTCTCCAAGCAGTCGTGCATCCTCGTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAG
GGCTGTCGGATTACGAGACTCCAGCACATTCTTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAAT
ACACAGAAATCAGTCAACTGGATGGTACAGATGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAG
ATTCAAAGCCTGGAACATTAGTCTGAACTGCAGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATT
TGTCTTCCGAGAGGATGTTCGTTTTAGAAACCTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATC
ACACACCAAGCCCCACAAAGCCCCTAAAGGAGGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGA
AGTATTGCCAAGAGAGGACTCAGTGTGAAGCCTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAA
ACATGAAAGGGCATTCAGGATGTCCCATGGCAATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGA
AGCTCCGGAGTCATTGCTCACTTCAGAGTTTGAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGA
CAGTATTGGAAAATTACTTGAAGCTGGATTTTCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTT
CATAAGCACCATAAAATGGGTTCTGGAAAAACTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCA
GCCCACTGAATAATTGACAAAGTCTGCTTGGAGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTG
ATGAGCTATTGTTCTGGCTGTTAATTCTCCAACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTT
GAAAAAGCATTTTAAGATGATACAGAAAGTATCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATG
GTGAACGTTAGAAAATTAAACAAGTCTGGATTCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAA
ACAACAACAACGACAAAAAGCTCCAAGCTGCAGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGC
TATGGTTTATTGTAGGGTTTTGTTTGTTTGTTTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAA
AATTACATAAAAGGTGCTCCTTTCCCCCTTCTTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGG
AACATTTTCTATCTATATTCCAAAGCATGTAATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATG
AAGTTTGGGAAAAAATTTTGGAAAAAAGACAAGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAA
ATAACCTTTTTGCATATTCTTTTATTGTTCTGACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGA
AAATGTTTACGTTTTCTTCCATTTATGTCAGGGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTT
CGGATTTTTATTTATAGTATTACCGTATTTTATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTA
TTGATGGCATATTCTACTTGAATTGGCAGTTTTTTCTTAATAGTACATTAAAAATAATGCTGTGTCTTACAATAAAGTTGCCTTAGAATT

>72866_72866_3_RBM38-FRMD4B_RBM38_chr20_55968388_ENST00000371219_FRMD4B_chr3_69267529_ENST00000398540_length(amino acids)=904AA_BP=114
MVGKSRRPPKLPSGFIFALSPQGIIFVLEGHISQALNFDGRSWNPGGIFVGEPQVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKP
RSLQTGFAIGVQQLHPTLIQRTYGYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFA
VEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQF
IMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDN
LLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESS
SLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILPPKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLT
RNAYSSSHLEPESSSQHCRQRSGSLESQSHLLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRT
RGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVYSKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQ
RDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCS
PSSRASSYSSVSSTNASGNWRTQLTIGLSDYETPAHSSYTSCYGNVYNPLPSPSRQYTEISQLDGTDGNQLEDNLESSEQRLFWHEDSKP

--------------------------------------------------------------
>72866_72866_4_RBM38-FRMD4B_RBM38_chr20_55968388_ENST00000371219_FRMD4B_chr3_69267529_ENST00000542259_length(transcript)=4682nt_BP=442nt
ATAAACATCAGCTTAAGTAAAAACGTCTTGAAGACACTTTCCTGCTTACCTTCCAAGCATAGCGTCGCAAACTCCTTCTCAGAGGAAAGT
CTCGGCCCTCACTGGTGGGCAAGTCCAGGCGGCCCCCCAAGCTCCCTTCGGGGTTCATTTTTGCCCTATCCCCGCAGGGGATTATTTTTG
TCCTTGAAGGCCACATTTCCCAGGCCTTGAACTTTGACGGGAGGAGCTGGAATCCAGGAGGCATCTTTGTGGGAGAGCCCCAGGTGACCA
TGGCCGACCGGGCGGCAGCTGAGAGGGCTTGCAAAGACCCGAACCCCATCATCGACGGCCGCAAGGCCAACGTGAACCTGGCATATCTGG
GCGCCAAGCCGCGGAGCCTCCAGACGGGCTTTGCCATTGGGGTGCAGCAGCTGCACCCCACCTTGATCCAGCGGACTTACGGGTATATGA
AAATAGTAGAAGCTCTACCGACTTACGGTGTCCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATA
AGGGAATTGGCCAATATGATATACAAGACAAGGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGA
AAAAATTTGCTGTTGAAGTTCATGATCCACGAAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGT
ATGCTAACTCTTCTCTCATCAAGTCCATTTGGGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAA
TTCCTTCAGCCAGGAGTTTAGATGAGATTGCAATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGA
AAAGTCAGTTCATCATGGCAAGTAATGGCAGTTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAA
TCCTTGAACTAAAGAAGAAGGAGAAACTATTACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTG
AGCTCACAGGCAAAATGCCAAAGGAGTATCCCCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAAT
TAGATGACAACTTGCTGCCGAGTGAAGAAGATCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTG
CAAAGAAACTTGCCAATGAGCCAGACCTTTGTAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGG
AGATTGAAAATGCAATAAACGAATACCGAATTAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCT
CAGAGAGTAGCTCTTTGTCTGACACCACCACCTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTC
ATTCTCCAAGAATTCTTCCCCCCAAGTCTCTTGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCA
GGCAGTCCAGAGAAATGCTGTCCACACACAGCAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGC
CAGTTCTTACCCGAAACGCCTACAGCAGCAGCCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGT
CCCAGTCCCACCTGCTCTCCGAGATGGACAGCGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCG
ATGACGGGTCTTCTTATACAAGCCAATCAAGCACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGG
ACACTCGCACCAGGGGTCGGAGGAGGTCAAAGAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATA
GTTTGAGGAATGGTGTTTACTCAAAGAGTCAGGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACT
TTTATTACAGTGGTGGTTATGTCTATGAGAATGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGAT
ATGAGCGCCAGAGGGACTACAGCAGATCCTTTCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAA
GGAAGGCTGCTGCAAAATCGGAGCACATCACCAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCT
CTGGGCAGAAGGATCAGGGACACAGCCCGCAGACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAG
TACCTTGTTCTCCAAGCAGTCGTGCATCCTCGTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAG
GGCTGTCGGATTACGAGACTCCAGCACATTCTTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAAT
ACACAGAAATCAGTCAACTGGATGGTACAGATGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAG
ATTCAAAGCCTGGAACATTAGTCTGAACTGCAGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATT
TGTCTTCCGAGAGGATGTTCGTTTTAGAAACCTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATC
ACACACCAAGCCCCACAAAGCCCCTAAAGGAGGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGA
AGTATTGCCAAGAGAGGACTCAGTGTGAAGCCTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAA
ACATGAAAGGGCATTCAGGATGTCCCATGGCAATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGA
AGCTCCGGAGTCATTGCTCACTTCAGAGTTTGAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGA
CAGTATTGGAAAATTACTTGAAGCTGGATTTTCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTT
CATAAGCACCATAAAATGGGTTCTGGAAAAACTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCA
GCCCACTGAATAATTGACAAAGTCTGCTTGGAGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTG
ATGAGCTATTGTTCTGGCTGTTAATTCTCCAACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTT
GAAAAAGCATTTTAAGATGATACAGAAAGTATCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATG
GTGAACGTTAGAAAATTAAACAAGTCTGGATTCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAA
ACAACAACAACGACAAAAAGCTCCAAGCTGCAGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGC
TATGGTTTATTGTAGGGTTTTGTTTGTTTGTTTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAA
AATTACATAAAAGGTGCTCCTTTCCCCCTTCTTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGG
AACATTTTCTATCTATATTCCAAAGCATGTAATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATG
AAGTTTGGGAAAAAATTTTGGAAAAAAGACAAGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAA
ATAACCTTTTTGCATATTCTTTTATTGTTCTGACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGA
AAATGTTTACGTTTTCTTCCATTTATGTCAGGGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTT
CGGATTTTTATTTATAGTATTACCGTATTTTATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTA
TTGATGGCATATTCTACTTGAATTGGCAGTTTTTTCTTAATAGTACATTAAAAATAATGCTGTGTCTTACAATAAAGTTGCCTTAGAATT

>72866_72866_4_RBM38-FRMD4B_RBM38_chr20_55968388_ENST00000371219_FRMD4B_chr3_69267529_ENST00000542259_length(amino acids)=904AA_BP=114
MVGKSRRPPKLPSGFIFALSPQGIIFVLEGHISQALNFDGRSWNPGGIFVGEPQVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKP
RSLQTGFAIGVQQLHPTLIQRTYGYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFA
VEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQF
IMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDN
LLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESS
SLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILPPKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLT
RNAYSSSHLEPESSSQHCRQRSGSLESQSHLLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRT
RGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVYSKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQ
RDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCS
PSSRASSYSSVSSTNASGNWRTQLTIGLSDYETPAHSSYTSCYGNVYNPLPSPSRQYTEISQLDGTDGNQLEDNLESSEQRLFWHEDSKP

--------------------------------------------------------------
>72866_72866_5_RBM38-FRMD4B_RBM38_chr20_55968389_ENST00000356208_FRMD4B_chr3_69267530_ENST00000398540_length(transcript)=4836nt_BP=591nt
GCAGCGCCGGTCGGGAGCGCAGCGCGGCGCACGTCGGCGCGCACGGCGGGACGGGCGCCGGAGTGGTCGGGCCTGGCGGCTGGACGGGCG
CCCCTCGCTGCCCCGCGCGCTCCCCGCCGCCCCCCATGAGCGCAGCCCCGCGCGGCCCGGGTCCGTAGGCGGCGGGGCGCCCCCCATGCT
GCTGCAGCCCGCGCCGTGCGCCCCGAGCGCGGGCTTCCCGCGGCCCCTGGCCGCCCCCGGCGCCATGCACGGCTCGCAGAAGGACACCAC
GTTCACCAAGATCTTCGTGGGCGGCCTGCCGTACCACACTACCGACGCCTCGCTCAGGAAGTACTTCGAGGGCTTCGGCGACATCGAGGA
GGCCGTGGTCATCACCGACCGCCAGACGGGCAAGTCCCGCGGCTACGGCTTCGTGACCATGGCCGACCGGGCGGCAGCTGAGAGGGCTTG
CAAAGACCCGAACCCCATCATCGACGGCCGCAAGGCCAACGTGAACCTGGCATATCTGGGCGCCAAGCCGCGGAGCCTCCAGACGGGCTT
TGCCATTGGGGTGCAGCAGCTGCACCCCACCTTGATCCAGCGGACTTACGGGTATATGAAAATAGTAGAAGCTCTACCGACTTACGGTGT
CCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATAAGGGAATTGGCCAATATGATATACAAGACAA
GGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGAAAAAATTTGCTGTTGAAGTTCATGATCCACG
AAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGTATGCTAACTCTTCTCTCATCAAGTCCATTTG
GGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAATTCCTTCAGCCAGGAGTTTAGATGAGATTGC
AATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGAAAAGTCAGTTCATCATGGCAAGTAATGGCAG
TTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAATCCTTGAACTAAAGAAGAAGGAGAAACTATT
ACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTGAGCTCACAGGCAAAATGCCAAAGGAGTATCC
CCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAATTAGATGACAACTTGCTGCCGAGTGAAGAAGA
TCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTGCAAAGAAACTTGCCAATGAGCCAGACCTTTG
TAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGGAGATTGAAAATGCAATAAACGAATACCGAAT
TAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCTCAGAGAGTAGCTCTTTGTCTGACACCACCAC
CTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTCATTCTCCAAGAATTCTTCCCCCCAAGTCTCT
TGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCAGGCAGTCCAGAGAAATGCTGTCCACACACAG
CAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGCCAGTTCTTACCCGAAACGCCTACAGCAGCAG
CCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGTCCCAGTCCCACCTGCTCTCCGAGATGGACAG
CGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCGATGACGGGTCTTCTTATACAAGCCAATCAAG
CACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGGACACTCGCACCAGGGGTCGGAGGAGGTCAAA
GAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATAGTTTGAGGAATGGTGTTTACTCAAAGAGTCA
GGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACTTTTATTACAGTGGTGGTTATGTCTATGAGAA
TGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGATATGAGCGCCAGAGGGACTACAGCAGATCCTT
TCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAAGGAAGGCTGCTGCAAAATCGGAGCACATCAC
CAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCTCTGGGCAGAAGGATCAGGGACACAGCCCGCA
GACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAGTACCTTGTTCTCCAAGCAGTCGTGCATCCTC
GTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAGGGCTGTCGGATTACGAGACTCCAGCACATTC
TTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAATACACAGAAATCAGTCAACTGGATGGTACAGA
TGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAGATTCAAAGCCTGGAACATTAGTCTGAACTGC
AGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATTTGTCTTCCGAGAGGATGTTCGTTTTAGAAAC
CTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATCACACACCAAGCCCCACAAAGCCCCTAAAGGA
GGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGAAGTATTGCCAAGAGAGGACTCAGTGTGAAGC
CTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAAACATGAAAGGGCATTCAGGATGTCCCATGGC
AATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGAAGCTCCGGAGTCATTGCTCACTTCAGAGTTT
GAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGACAGTATTGGAAAATTACTTGAAGCTGGATTT
TCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTTCATAAGCACCATAAAATGGGTTCTGGAAAAA
CTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCAGCCCACTGAATAATTGACAAAGTCTGCTTGG
AGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTGATGAGCTATTGTTCTGGCTGTTAATTCTCCA
ACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTTGAAAAAGCATTTTAAGATGATACAGAAAGTA
TCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATGGTGAACGTTAGAAAATTAAACAAGTCTGGAT
TCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAAACAACAACAACGACAAAAAGCTCCAAGCTGC
AGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGCTATGGTTTATTGTAGGGTTTTGTTTGTTTGT
TTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAAAATTACATAAAAGGTGCTCCTTTCCCCCTTC
TTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGGAACATTTTCTATCTATATTCCAAAGCATGTA
ATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATGAAGTTTGGGAAAAAATTTTGGAAAAAAGACA
AGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAAATAACCTTTTTGCATATTCTTTTATTGTTCT
GACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGAAAATGTTTACGTTTTCTTCCATTTATGTCAG
GGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTTCGGATTTTTATTTATAGTATTACCGTATTTT
ATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTATTGATGGCATATTCTACTTGAATTGGCAGTT

>72866_72866_5_RBM38-FRMD4B_RBM38_chr20_55968389_ENST00000356208_FRMD4B_chr3_69267530_ENST00000398540_length(amino acids)=961AA_BP=171
MDGRPSLPRALPAAPHERSPARPGSVGGGAPPMLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFG
DIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGYMKIVEALP
TYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLI
KSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKK
EKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANE
PDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILP
PKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLESQSHLLS
EMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVY
SKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKS
EHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSDYET

--------------------------------------------------------------
>72866_72866_6_RBM38-FRMD4B_RBM38_chr20_55968389_ENST00000356208_FRMD4B_chr3_69267530_ENST00000542259_length(transcript)=4831nt_BP=591nt
GCAGCGCCGGTCGGGAGCGCAGCGCGGCGCACGTCGGCGCGCACGGCGGGACGGGCGCCGGAGTGGTCGGGCCTGGCGGCTGGACGGGCG
CCCCTCGCTGCCCCGCGCGCTCCCCGCCGCCCCCCATGAGCGCAGCCCCGCGCGGCCCGGGTCCGTAGGCGGCGGGGCGCCCCCCATGCT
GCTGCAGCCCGCGCCGTGCGCCCCGAGCGCGGGCTTCCCGCGGCCCCTGGCCGCCCCCGGCGCCATGCACGGCTCGCAGAAGGACACCAC
GTTCACCAAGATCTTCGTGGGCGGCCTGCCGTACCACACTACCGACGCCTCGCTCAGGAAGTACTTCGAGGGCTTCGGCGACATCGAGGA
GGCCGTGGTCATCACCGACCGCCAGACGGGCAAGTCCCGCGGCTACGGCTTCGTGACCATGGCCGACCGGGCGGCAGCTGAGAGGGCTTG
CAAAGACCCGAACCCCATCATCGACGGCCGCAAGGCCAACGTGAACCTGGCATATCTGGGCGCCAAGCCGCGGAGCCTCCAGACGGGCTT
TGCCATTGGGGTGCAGCAGCTGCACCCCACCTTGATCCAGCGGACTTACGGGTATATGAAAATAGTAGAAGCTCTACCGACTTACGGTGT
CCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATAAGGGAATTGGCCAATATGATATACAAGACAA
GGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGAAAAAATTTGCTGTTGAAGTTCATGATCCACG
AAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGTATGCTAACTCTTCTCTCATCAAGTCCATTTG
GGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAATTCCTTCAGCCAGGAGTTTAGATGAGATTGC
AATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGAAAAGTCAGTTCATCATGGCAAGTAATGGCAG
TTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAATCCTTGAACTAAAGAAGAAGGAGAAACTATT
ACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTGAGCTCACAGGCAAAATGCCAAAGGAGTATCC
CCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAATTAGATGACAACTTGCTGCCGAGTGAAGAAGA
TCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTGCAAAGAAACTTGCCAATGAGCCAGACCTTTG
TAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGGAGATTGAAAATGCAATAAACGAATACCGAAT
TAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCTCAGAGAGTAGCTCTTTGTCTGACACCACCAC
CTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTCATTCTCCAAGAATTCTTCCCCCCAAGTCTCT
TGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCAGGCAGTCCAGAGAAATGCTGTCCACACACAG
CAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGCCAGTTCTTACCCGAAACGCCTACAGCAGCAG
CCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGTCCCAGTCCCACCTGCTCTCCGAGATGGACAG
CGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCGATGACGGGTCTTCTTATACAAGCCAATCAAG
CACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGGACACTCGCACCAGGGGTCGGAGGAGGTCAAA
GAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATAGTTTGAGGAATGGTGTTTACTCAAAGAGTCA
GGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACTTTTATTACAGTGGTGGTTATGTCTATGAGAA
TGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGATATGAGCGCCAGAGGGACTACAGCAGATCCTT
TCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAAGGAAGGCTGCTGCAAAATCGGAGCACATCAC
CAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCTCTGGGCAGAAGGATCAGGGACACAGCCCGCA
GACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAGTACCTTGTTCTCCAAGCAGTCGTGCATCCTC
GTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAGGGCTGTCGGATTACGAGACTCCAGCACATTC
TTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAATACACAGAAATCAGTCAACTGGATGGTACAGA
TGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAGATTCAAAGCCTGGAACATTAGTCTGAACTGC
AGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATTTGTCTTCCGAGAGGATGTTCGTTTTAGAAAC
CTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATCACACACCAAGCCCCACAAAGCCCCTAAAGGA
GGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGAAGTATTGCCAAGAGAGGACTCAGTGTGAAGC
CTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAAACATGAAAGGGCATTCAGGATGTCCCATGGC
AATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGAAGCTCCGGAGTCATTGCTCACTTCAGAGTTT
GAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGACAGTATTGGAAAATTACTTGAAGCTGGATTT
TCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTTCATAAGCACCATAAAATGGGTTCTGGAAAAA
CTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCAGCCCACTGAATAATTGACAAAGTCTGCTTGG
AGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTGATGAGCTATTGTTCTGGCTGTTAATTCTCCA
ACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTTGAAAAAGCATTTTAAGATGATACAGAAAGTA
TCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATGGTGAACGTTAGAAAATTAAACAAGTCTGGAT
TCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAAACAACAACAACGACAAAAAGCTCCAAGCTGC
AGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGCTATGGTTTATTGTAGGGTTTTGTTTGTTTGT
TTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAAAATTACATAAAAGGTGCTCCTTTCCCCCTTC
TTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGGAACATTTTCTATCTATATTCCAAAGCATGTA
ATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATGAAGTTTGGGAAAAAATTTTGGAAAAAAGACA
AGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAAATAACCTTTTTGCATATTCTTTTATTGTTCT
GACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGAAAATGTTTACGTTTTCTTCCATTTATGTCAG
GGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTTCGGATTTTTATTTATAGTATTACCGTATTTT
ATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTATTGATGGCATATTCTACTTGAATTGGCAGTT

>72866_72866_6_RBM38-FRMD4B_RBM38_chr20_55968389_ENST00000356208_FRMD4B_chr3_69267530_ENST00000542259_length(amino acids)=961AA_BP=171
MDGRPSLPRALPAAPHERSPARPGSVGGGAPPMLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFG
DIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGYMKIVEALP
TYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLI
KSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKK
EKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANE
PDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILP
PKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLESQSHLLS
EMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVY
SKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKS
EHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSDYET

--------------------------------------------------------------
>72866_72866_7_RBM38-FRMD4B_RBM38_chr20_55968389_ENST00000371219_FRMD4B_chr3_69267530_ENST00000398540_length(transcript)=4687nt_BP=442nt
ATAAACATCAGCTTAAGTAAAAACGTCTTGAAGACACTTTCCTGCTTACCTTCCAAGCATAGCGTCGCAAACTCCTTCTCAGAGGAAAGT
CTCGGCCCTCACTGGTGGGCAAGTCCAGGCGGCCCCCCAAGCTCCCTTCGGGGTTCATTTTTGCCCTATCCCCGCAGGGGATTATTTTTG
TCCTTGAAGGCCACATTTCCCAGGCCTTGAACTTTGACGGGAGGAGCTGGAATCCAGGAGGCATCTTTGTGGGAGAGCCCCAGGTGACCA
TGGCCGACCGGGCGGCAGCTGAGAGGGCTTGCAAAGACCCGAACCCCATCATCGACGGCCGCAAGGCCAACGTGAACCTGGCATATCTGG
GCGCCAAGCCGCGGAGCCTCCAGACGGGCTTTGCCATTGGGGTGCAGCAGCTGCACCCCACCTTGATCCAGCGGACTTACGGGTATATGA
AAATAGTAGAAGCTCTACCGACTTACGGTGTCCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATA
AGGGAATTGGCCAATATGATATACAAGACAAGGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGA
AAAAATTTGCTGTTGAAGTTCATGATCCACGAAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGT
ATGCTAACTCTTCTCTCATCAAGTCCATTTGGGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAA
TTCCTTCAGCCAGGAGTTTAGATGAGATTGCAATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGA
AAAGTCAGTTCATCATGGCAAGTAATGGCAGTTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAA
TCCTTGAACTAAAGAAGAAGGAGAAACTATTACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTG
AGCTCACAGGCAAAATGCCAAAGGAGTATCCCCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAAT
TAGATGACAACTTGCTGCCGAGTGAAGAAGATCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTG
CAAAGAAACTTGCCAATGAGCCAGACCTTTGTAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGG
AGATTGAAAATGCAATAAACGAATACCGAATTAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCT
CAGAGAGTAGCTCTTTGTCTGACACCACCACCTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTC
ATTCTCCAAGAATTCTTCCCCCCAAGTCTCTTGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCA
GGCAGTCCAGAGAAATGCTGTCCACACACAGCAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGC
CAGTTCTTACCCGAAACGCCTACAGCAGCAGCCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGT
CCCAGTCCCACCTGCTCTCCGAGATGGACAGCGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCG
ATGACGGGTCTTCTTATACAAGCCAATCAAGCACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGG
ACACTCGCACCAGGGGTCGGAGGAGGTCAAAGAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATA
GTTTGAGGAATGGTGTTTACTCAAAGAGTCAGGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACT
TTTATTACAGTGGTGGTTATGTCTATGAGAATGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGAT
ATGAGCGCCAGAGGGACTACAGCAGATCCTTTCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAA
GGAAGGCTGCTGCAAAATCGGAGCACATCACCAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCT
CTGGGCAGAAGGATCAGGGACACAGCCCGCAGACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAG
TACCTTGTTCTCCAAGCAGTCGTGCATCCTCGTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAG
GGCTGTCGGATTACGAGACTCCAGCACATTCTTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAAT
ACACAGAAATCAGTCAACTGGATGGTACAGATGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAG
ATTCAAAGCCTGGAACATTAGTCTGAACTGCAGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATT
TGTCTTCCGAGAGGATGTTCGTTTTAGAAACCTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATC
ACACACCAAGCCCCACAAAGCCCCTAAAGGAGGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGA
AGTATTGCCAAGAGAGGACTCAGTGTGAAGCCTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAA
ACATGAAAGGGCATTCAGGATGTCCCATGGCAATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGA
AGCTCCGGAGTCATTGCTCACTTCAGAGTTTGAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGA
CAGTATTGGAAAATTACTTGAAGCTGGATTTTCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTT
CATAAGCACCATAAAATGGGTTCTGGAAAAACTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCA
GCCCACTGAATAATTGACAAAGTCTGCTTGGAGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTG
ATGAGCTATTGTTCTGGCTGTTAATTCTCCAACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTT
GAAAAAGCATTTTAAGATGATACAGAAAGTATCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATG
GTGAACGTTAGAAAATTAAACAAGTCTGGATTCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAA
ACAACAACAACGACAAAAAGCTCCAAGCTGCAGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGC
TATGGTTTATTGTAGGGTTTTGTTTGTTTGTTTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAA
AATTACATAAAAGGTGCTCCTTTCCCCCTTCTTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGG
AACATTTTCTATCTATATTCCAAAGCATGTAATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATG
AAGTTTGGGAAAAAATTTTGGAAAAAAGACAAGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAA
ATAACCTTTTTGCATATTCTTTTATTGTTCTGACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGA
AAATGTTTACGTTTTCTTCCATTTATGTCAGGGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTT
CGGATTTTTATTTATAGTATTACCGTATTTTATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTA
TTGATGGCATATTCTACTTGAATTGGCAGTTTTTTCTTAATAGTACATTAAAAATAATGCTGTGTCTTACAATAAAGTTGCCTTAGAATT

>72866_72866_7_RBM38-FRMD4B_RBM38_chr20_55968389_ENST00000371219_FRMD4B_chr3_69267530_ENST00000398540_length(amino acids)=904AA_BP=114
MVGKSRRPPKLPSGFIFALSPQGIIFVLEGHISQALNFDGRSWNPGGIFVGEPQVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKP
RSLQTGFAIGVQQLHPTLIQRTYGYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFA
VEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQF
IMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDN
LLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESS
SLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILPPKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLT
RNAYSSSHLEPESSSQHCRQRSGSLESQSHLLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRT
RGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVYSKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQ
RDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCS
PSSRASSYSSVSSTNASGNWRTQLTIGLSDYETPAHSSYTSCYGNVYNPLPSPSRQYTEISQLDGTDGNQLEDNLESSEQRLFWHEDSKP

--------------------------------------------------------------
>72866_72866_8_RBM38-FRMD4B_RBM38_chr20_55968389_ENST00000371219_FRMD4B_chr3_69267530_ENST00000542259_length(transcript)=4682nt_BP=442nt
ATAAACATCAGCTTAAGTAAAAACGTCTTGAAGACACTTTCCTGCTTACCTTCCAAGCATAGCGTCGCAAACTCCTTCTCAGAGGAAAGT
CTCGGCCCTCACTGGTGGGCAAGTCCAGGCGGCCCCCCAAGCTCCCTTCGGGGTTCATTTTTGCCCTATCCCCGCAGGGGATTATTTTTG
TCCTTGAAGGCCACATTTCCCAGGCCTTGAACTTTGACGGGAGGAGCTGGAATCCAGGAGGCATCTTTGTGGGAGAGCCCCAGGTGACCA
TGGCCGACCGGGCGGCAGCTGAGAGGGCTTGCAAAGACCCGAACCCCATCATCGACGGCCGCAAGGCCAACGTGAACCTGGCATATCTGG
GCGCCAAGCCGCGGAGCCTCCAGACGGGCTTTGCCATTGGGGTGCAGCAGCTGCACCCCACCTTGATCCAGCGGACTTACGGGTATATGA
AAATAGTAGAAGCTCTACCGACTTACGGTGTCCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATA
AGGGAATTGGCCAATATGATATACAAGACAAGGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGA
AAAAATTTGCTGTTGAAGTTCATGATCCACGAAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGT
ATGCTAACTCTTCTCTCATCAAGTCCATTTGGGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAA
TTCCTTCAGCCAGGAGTTTAGATGAGATTGCAATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGA
AAAGTCAGTTCATCATGGCAAGTAATGGCAGTTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAA
TCCTTGAACTAAAGAAGAAGGAGAAACTATTACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTG
AGCTCACAGGCAAAATGCCAAAGGAGTATCCCCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAAT
TAGATGACAACTTGCTGCCGAGTGAAGAAGATCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTG
CAAAGAAACTTGCCAATGAGCCAGACCTTTGTAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGG
AGATTGAAAATGCAATAAACGAATACCGAATTAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCT
CAGAGAGTAGCTCTTTGTCTGACACCACCACCTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTC
ATTCTCCAAGAATTCTTCCCCCCAAGTCTCTTGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCA
GGCAGTCCAGAGAAATGCTGTCCACACACAGCAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGC
CAGTTCTTACCCGAAACGCCTACAGCAGCAGCCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGT
CCCAGTCCCACCTGCTCTCCGAGATGGACAGCGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCG
ATGACGGGTCTTCTTATACAAGCCAATCAAGCACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGG
ACACTCGCACCAGGGGTCGGAGGAGGTCAAAGAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATA
GTTTGAGGAATGGTGTTTACTCAAAGAGTCAGGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACT
TTTATTACAGTGGTGGTTATGTCTATGAGAATGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGAT
ATGAGCGCCAGAGGGACTACAGCAGATCCTTTCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAA
GGAAGGCTGCTGCAAAATCGGAGCACATCACCAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCT
CTGGGCAGAAGGATCAGGGACACAGCCCGCAGACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAG
TACCTTGTTCTCCAAGCAGTCGTGCATCCTCGTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAG
GGCTGTCGGATTACGAGACTCCAGCACATTCTTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAAT
ACACAGAAATCAGTCAACTGGATGGTACAGATGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAG
ATTCAAAGCCTGGAACATTAGTCTGAACTGCAGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATT
TGTCTTCCGAGAGGATGTTCGTTTTAGAAACCTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATC
ACACACCAAGCCCCACAAAGCCCCTAAAGGAGGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGA
AGTATTGCCAAGAGAGGACTCAGTGTGAAGCCTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAA
ACATGAAAGGGCATTCAGGATGTCCCATGGCAATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGA
AGCTCCGGAGTCATTGCTCACTTCAGAGTTTGAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGA
CAGTATTGGAAAATTACTTGAAGCTGGATTTTCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTT
CATAAGCACCATAAAATGGGTTCTGGAAAAACTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCA
GCCCACTGAATAATTGACAAAGTCTGCTTGGAGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTG
ATGAGCTATTGTTCTGGCTGTTAATTCTCCAACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTT
GAAAAAGCATTTTAAGATGATACAGAAAGTATCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATG
GTGAACGTTAGAAAATTAAACAAGTCTGGATTCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAA
ACAACAACAACGACAAAAAGCTCCAAGCTGCAGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGC
TATGGTTTATTGTAGGGTTTTGTTTGTTTGTTTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAA
AATTACATAAAAGGTGCTCCTTTCCCCCTTCTTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGG
AACATTTTCTATCTATATTCCAAAGCATGTAATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATG
AAGTTTGGGAAAAAATTTTGGAAAAAAGACAAGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAA
ATAACCTTTTTGCATATTCTTTTATTGTTCTGACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGA
AAATGTTTACGTTTTCTTCCATTTATGTCAGGGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTT
CGGATTTTTATTTATAGTATTACCGTATTTTATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTA
TTGATGGCATATTCTACTTGAATTGGCAGTTTTTTCTTAATAGTACATTAAAAATAATGCTGTGTCTTACAATAAAGTTGCCTTAGAATT

>72866_72866_8_RBM38-FRMD4B_RBM38_chr20_55968389_ENST00000371219_FRMD4B_chr3_69267530_ENST00000542259_length(amino acids)=904AA_BP=114
MVGKSRRPPKLPSGFIFALSPQGIIFVLEGHISQALNFDGRSWNPGGIFVGEPQVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKP
RSLQTGFAIGVQQLHPTLIQRTYGYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFA
VEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQF
IMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDN
LLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESS
SLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILPPKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLT
RNAYSSSHLEPESSSQHCRQRSGSLESQSHLLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRT
RGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVYSKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQ
RDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCS
PSSRASSYSSVSSTNASGNWRTQLTIGLSDYETPAHSSYTSCYGNVYNPLPSPSRQYTEISQLDGTDGNQLEDNLESSEQRLFWHEDSKP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RBM38-FRMD4B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RBM38-FRMD4B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RBM38-FRMD4B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource