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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RC3H2-GNA14 (FusionGDB2 ID:73115)

Fusion Gene Summary for RC3H2-GNA14

check button Fusion gene summary
Fusion gene informationFusion gene name: RC3H2-GNA14
Fusion gene ID: 73115
HgeneTgene
Gene symbol

RC3H2

GNA14

Gene ID

54542

9630

Gene namering finger and CCCH-type domains 2G protein subunit alpha 14
SynonymsMNAB|RNF164-
Cytomap

9q33.2

9q21.2

Type of geneprotein-codingprotein-coding
Descriptionroquin-2RING finger protein 164RING-type E3 ubiquitin transferase Roquin-2membrane associated DNA binding proteinmembrane-associated nucleic acid-binding proteinring finger and CCCH-type zinc finger domain-containing protein 2ring finger and CCCH-tyguanine nucleotide-binding protein subunit alpha-14g alpha-14guanine nucleotide binding protein (G protein), alpha 14guanine nucleotide-binding protein 14
Modification date2020031320200313
UniProtAcc.

O95837

Ensembl transtripts involved in fusion geneENST00000335387, ENST00000357244, 
ENST00000373665, ENST00000373670, 
ENST00000423239, ENST00000471874, 
ENST00000478216, 		ENST00000464095, 
ENST00000341700, 
Fusion gene scores* DoF score7 X 8 X 6=3367 X 4 X 5=140
# samples 77
** MAII scorelog2(7/336*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/140*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RC3H2 [Title/Abstract] AND GNA14 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRC3H2(125645483)-GNA14(80049438), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRC3H2

GO:0000209

protein polyubiquitination

26489670


check buttonFusion gene breakpoints across RC3H2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GNA14 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A4RW-01ARC3H2chr9

125645483

-GNA14chr9

80049438

-


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Fusion Gene ORF analysis for RC3H2-GNA14

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000335387ENST00000464095RC3H2chr9

125645483

-GNA14chr9

80049438

-
5CDS-intronENST00000357244ENST00000464095RC3H2chr9

125645483

-GNA14chr9

80049438

-
5CDS-intronENST00000373665ENST00000464095RC3H2chr9

125645483

-GNA14chr9

80049438

-
5CDS-intronENST00000373670ENST00000464095RC3H2chr9

125645483

-GNA14chr9

80049438

-
5CDS-intronENST00000423239ENST00000464095RC3H2chr9

125645483

-GNA14chr9

80049438

-
In-frameENST00000335387ENST00000341700RC3H2chr9

125645483

-GNA14chr9

80049438

-
In-frameENST00000357244ENST00000341700RC3H2chr9

125645483

-GNA14chr9

80049438

-
In-frameENST00000373665ENST00000341700RC3H2chr9

125645483

-GNA14chr9

80049438

-
In-frameENST00000373670ENST00000341700RC3H2chr9

125645483

-GNA14chr9

80049438

-
In-frameENST00000423239ENST00000341700RC3H2chr9

125645483

-GNA14chr9

80049438

-
intron-3CDSENST00000471874ENST00000341700RC3H2chr9

125645483

-GNA14chr9

80049438

-
intron-3CDSENST00000478216ENST00000341700RC3H2chr9

125645483

-GNA14chr9

80049438

-
intron-intronENST00000471874ENST00000464095RC3H2chr9

125645483

-GNA14chr9

80049438

-
intron-intronENST00000478216ENST00000464095RC3H2chr9

125645483

-GNA14chr9

80049438

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000373670RC3H2chr9125645483-ENST00000341700GNA14chr980049438-301913606012118505
ENST00000357244RC3H2chr9125645483-ENST00000341700GNA14chr980049438-265910002411758505
ENST00000423239RC3H2chr9125645483-ENST00000341700GNA14chr980049438-271710582991816505
ENST00000373665RC3H2chr9125645483-ENST00000341700GNA14chr980049438-265910002411758505
ENST00000335387RC3H2chr9125645483-ENST00000341700GNA14chr980049438-25919321731690505

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000373670ENST00000341700RC3H2chr9125645483-GNA14chr980049438-0.0001788450.9998211
ENST00000357244ENST00000341700RC3H2chr9125645483-GNA14chr980049438-0.0002914070.9997086
ENST00000423239ENST00000341700RC3H2chr9125645483-GNA14chr980049438-0.0002880710.99971193
ENST00000373665ENST00000341700RC3H2chr9125645483-GNA14chr980049438-0.0002914070.9997086
ENST00000335387ENST00000341700RC3H2chr9125645483-GNA14chr980049438-0.0002863250.9997136

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Fusion Genomic Features for RC3H2-GNA14


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RC3H2-GNA14


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:125645483/chr9:80049438)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.GNA14

O95837

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRC3H2chr9:125645483chr9:80049438ENST00000357244-52191_1702531192.0RegionHEPN-N
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373665-51191_170253479.0RegionHEPN-N
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373670-42091_1702531192.0RegionHEPN-N
HgeneRC3H2chr9:125645483chr9:80049438ENST00000423239-51891_1702531065.0RegionHEPN-N
HgeneRC3H2chr9:125645483chr9:80049438ENST00000357244-52114_542531192.0Zinc fingerRING-type%3B degenerate
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373665-51114_54253479.0Zinc fingerRING-type%3B degenerate
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373670-42014_542531192.0Zinc fingerRING-type%3B degenerate
HgeneRC3H2chr9:125645483chr9:80049438ENST00000423239-51814_542531065.0Zinc fingerRING-type%3B degenerate
TgeneGNA14chr9:125645483chr9:80049438ENST0000034170017176_182103356.0Nucleotide bindingGTP
TgeneGNA14chr9:125645483chr9:80049438ENST0000034170017201_205103356.0Nucleotide bindingGTP
TgeneGNA14chr9:125645483chr9:80049438ENST0000034170017270_273103356.0Nucleotide bindingGTP
TgeneGNA14chr9:125645483chr9:80049438ENST0000034170017174_182103356.0RegionG2 motif
TgeneGNA14chr9:125645483chr9:80049438ENST0000034170017197_206103356.0RegionG3 motif
TgeneGNA14chr9:125645483chr9:80049438ENST0000034170017266_273103356.0RegionG4 motif
TgeneGNA14chr9:125645483chr9:80049438ENST0000034170017325_330103356.0RegionG5 motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRC3H2chr9:125645483chr9:80049438ENST00000357244-521576_7042531192.0Compositional biasNote=Pro-rich
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373665-511576_704253479.0Compositional biasNote=Pro-rich
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373670-420576_7042531192.0Compositional biasNote=Pro-rich
HgeneRC3H2chr9:125645483chr9:80049438ENST00000423239-518576_7042531065.0Compositional biasNote=Pro-rich
HgeneRC3H2chr9:125645483chr9:80049438ENST00000471874-13576_7040219.0Compositional biasNote=Pro-rich
HgeneRC3H2chr9:125645483chr9:80049438ENST00000357244-521171_3252531192.0RegionROQ
HgeneRC3H2chr9:125645483chr9:80049438ENST00000357244-521326_3962531192.0RegionHEPN-C
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373665-511171_325253479.0RegionROQ
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373665-511326_396253479.0RegionHEPN-C
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373670-420171_3252531192.0RegionROQ
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373670-420326_3962531192.0RegionHEPN-C
HgeneRC3H2chr9:125645483chr9:80049438ENST00000423239-518171_3252531065.0RegionROQ
HgeneRC3H2chr9:125645483chr9:80049438ENST00000423239-518326_3962531065.0RegionHEPN-C
HgeneRC3H2chr9:125645483chr9:80049438ENST00000471874-13171_3250219.0RegionROQ
HgeneRC3H2chr9:125645483chr9:80049438ENST00000471874-13326_3960219.0RegionHEPN-C
HgeneRC3H2chr9:125645483chr9:80049438ENST00000471874-1391_1700219.0RegionHEPN-N
HgeneRC3H2chr9:125645483chr9:80049438ENST00000357244-521410_4382531192.0Zinc fingerC3H1-type
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373665-511410_438253479.0Zinc fingerC3H1-type
HgeneRC3H2chr9:125645483chr9:80049438ENST00000373670-420410_4382531192.0Zinc fingerC3H1-type
HgeneRC3H2chr9:125645483chr9:80049438ENST00000423239-518410_4382531065.0Zinc fingerC3H1-type
HgeneRC3H2chr9:125645483chr9:80049438ENST00000471874-1314_540219.0Zinc fingerRING-type%3B degenerate
HgeneRC3H2chr9:125645483chr9:80049438ENST00000471874-13410_4380219.0Zinc fingerC3H1-type
TgeneGNA14chr9:125645483chr9:80049438ENST000003417001734_355103356.0DomainG-alpha
TgeneGNA14chr9:125645483chr9:80049438ENST000003417001742_49103356.0Nucleotide bindingGTP
TgeneGNA14chr9:125645483chr9:80049438ENST000003417001737_50103356.0RegionG1 motif


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Fusion Gene Sequence for RC3H2-GNA14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>73115_73115_1_RC3H2-GNA14_RC3H2_chr9_125645483_ENST00000335387_GNA14_chr9_80049438_ENST00000341700_length(transcript)=2591nt_BP=932nt
CTCCGCCGAGCTCTGCCCCGGCGAGACGAGGCGCCTCCGTCGCCAAGCCGCGCCGTCGCGGGGCTCCCGGGAGCGGCCCTTAGCGACCCC
GCCCGGGCCCCCTCAGCTTACAAAACACTACACAGCAAAATAATGATCTGCTAGACTGCTAACCCGAGCATCCAGCTTCCACAATGCCTG
TGCAGGCAGCTCAATGGACAGAATTTCTGTCCTGTCCAATCTGCTATAATGAATTTGATGAGAATGTGCACAAACCCATCAGTTTAGGTT
GTTCACACACTGTTTGCAAGACCTGCTTGAATAAACTTCATCGAAAAGCTTGTCCTTTTGACCAGACTGCCATCAACACAGATATTGATG
TACTTCCTGTCAACTTCGCACTTCTCCAGTTAGTTGGAGCCCAGGTACCAGATCATCAGTCAATTAAGTTAAGTAATCTAGGTGAGAATA
AACACTATGAGGTTGCAAAGAAATGCGTTGAGGATTTGGCACTCTACTTAAAACCACTAAGTGGAGGTAAAGGTGTAGCTAGCTTGAACC
AGAGTGCACTGAGCCGTCCAATGCAAAGGAAACTGGTGACACTTGTAAACTGTCAACTGGTGGAGGAAGAAGGTCGTGTAAGAGCCATGC
GAGCAGCTCGTTCCCTTGGAGAAAGAACTGTAACAGAACTGATATTACAGCACCAGAACCCTCAGCAGTTGTCTGCCAATCTATGGGCCG
CTGTCAGGGCTCGAGGATGCCAGTTTTTAGGGCCAGCTATGCAAGAAGAGGCCTTGAAGCTGGTGTTACTGGCATTAGAAGATGGTTCTG
CCCTCTCAAGGAAAGTTCTGGTACTTTTTGTTGTGCAGAGACTAGAACCAAGATTTCCTCAGGCATCAAAAACAAGTATTGGTCATGTTG
TGCAACTACTGTATCGAGCTTCTTGTTTTAAGGAAAATGCCCAGATAATCAGAGAAGTGGAAGTGGACAAGGTCTCCATGCTCTCCAGGG
AGCAGGTGGAGGCCATCAAGCAGCTCTGGCAAGATCCAGGCATCCAGGAGTGTTACGACAGGAGGAGGGAGTACCAGCTGTCGGACTCTG
CCAAATATTACCTGACTGACATTGACCGCATCGCCACACCATCATTCGTGCCTACCCAACAAGATGTGCTTCGCGTCCGAGTGCCCACCA
CCGGCATCATTGAGTATCCATTTGACTTGGAAAACATCATCTTTCGGATGGTGGATGTTGGTGGCCAACGATCGGAAAGACGGAAGTGGA
TTCACTGCTTTGAGAGTGTCACCTCCATTATTTTCTTGGTTGCTCTGAGTGAATATGACCAGGTCCTGGCTGAGTGTGACAACGAGAATC
GCATGGAAGAGAGCAAAGCCTTATTTAAAACCATCATCACCTACCCCTGGTTTCTGAATTCGTCTGTGATTTTATTCTTGAACAAGAAGG
ATCTTTTGGAAGAGAAAATCATGTACTCTCATCTAATTAGCTATTTCCCAGAATACACAGGACCGAAACAGGATGTCAGAGCTGCCAGAG
ACTTTATCCTGAAGCTTTACCAAGATCAGAATCCTGACAAAGAGAAAGTCATCTACTCTCACTTCACATGTGCTACAGATACAGACAATA
TTCGCTTTGTGTTTGCTGCTGTCAAAGACACAATTCTACAGCTAAACCTAAGGGAATTCAACCTTGTCTAAAAGCTGCTGCCCACTCCTC
CCCTATAACAGAAGATGTGATTTGCAAACTCCTTGTTTTATTTGCAAGTGCTTCTGACATCACCAGAGCCAGCCCCATGCCAGGAACTAA
GGATGTCATGTAGATCGTGGGGACAGAGATGGGTGATGGAACTTGGAAGATATTTGAGTTTACCAACATACTTTAAAAGTCCTTACATCC
CAAATTGTGTTTATAATTATTTTCTTGACTTTTGGCTATAAGATTTTGTGTAATTTTTGAATTTGGTGTTTTCTAGAATTTTTAAAAGCC
ACTTTGATTTAGTTTTAAATATGTTTAAAAATAGCGATTAAAATTATGTAAGCAAGGAGCCTGTTAGTTTATAGATCATGCCTTCAAACC
TCTAGAGTTAATTTGGGTGACTTTTTTAAAAATAAGAATGTTAATGGGTTTGAAGCTTTTTATTAAACCTTGTAATTTAGAGACATTTTT
AATTGTGTTTCTCACCTCATGCTGAAGGGTGACTCCTTTAACATGCCACCAAAGATTTTTTTTAAACACTTGGTTCTTTTTGTGTGTTAA
CTTTCTAAGCCAAATTAATGGATATATAAGTATATCTAATTTAGCTTTGCCACAGTTTGATCACCAAGAAGCCAAAGCTGACATAGAGTA
AATGGGCTCTAGATAGCATATATGTTTTATTGGTGAAAAATGTGTGTGTGTGCACGTGTGTGTGTGTGTACATTTTTACCCCCAATGTAT
ATGACCAGATCTTAAAAATGTATGAAATGGCTAGAAGTCCACATTGTTTGACAAATGTTACGTAACCCTGCCAAAGTTCTGATGGCCACC

>73115_73115_1_RC3H2-GNA14_RC3H2_chr9_125645483_ENST00000335387_GNA14_chr9_80049438_ENST00000341700_length(amino acids)=505AA_BP=253
MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTDIDVLPVNFALLQLVGAQVPDHQSIKLSNLG
ENKHYEVAKKCVEDLALYLKPLSGGKGVASLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL
WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIGHVVQLLYRASCFKENAQIIREVEVDKVSML
SREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERR
KWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRA

--------------------------------------------------------------
>73115_73115_2_RC3H2-GNA14_RC3H2_chr9_125645483_ENST00000357244_GNA14_chr9_80049438_ENST00000341700_length(transcript)=2659nt_BP=1000nt
GTCGCGGCCTTCGCCGCCGCCAACGGGGCTGTCCCTGTAGCTCCCGATGGAGTTTGAGGTCGTGAAACCTCCGCCGAGCTCTGCCCCGGC
GAGACGAGGCGCCTCCGTCGCCAAGCCGCGCCGTCGCGGGGCTCCCGGGAGCGGCCCTTAGCGACCCCGCCCGGGCCCCCTCAGCTTACA
AAACACTACACAGCAAAATAATGATCTGCTAGACTGCTAACCCGAGCATCCAGCTTCCACAATGCCTGTGCAGGCAGCTCAATGGACAGA
ATTTCTGTCCTGTCCAATCTGCTATAATGAATTTGATGAGAATGTGCACAAACCCATCAGTTTAGGTTGTTCACACACTGTTTGCAAGAC
CTGCTTGAATAAACTTCATCGAAAAGCTTGTCCTTTTGACCAGACTGCCATCAACACAGATATTGATGTACTTCCTGTCAACTTCGCACT
TCTCCAGTTAGTTGGAGCCCAGGTACCAGATCATCAGTCAATTAAGTTAAGTAATCTAGGTGAGAATAAACACTATGAGGTTGCAAAGAA
ATGCGTTGAGGATTTGGCACTCTACTTAAAACCACTAAGTGGAGGTAAAGGTGTAGCTAGCTTGAACCAGAGTGCACTGAGCCGTCCAAT
GCAAAGGAAACTGGTGACACTTGTAAACTGTCAACTGGTGGAGGAAGAAGGTCGTGTAAGAGCCATGCGAGCAGCTCGTTCCCTTGGAGA
AAGAACTGTAACAGAACTGATATTACAGCACCAGAACCCTCAGCAGTTGTCTGCCAATCTATGGGCCGCTGTCAGGGCTCGAGGATGCCA
GTTTTTAGGGCCAGCTATGCAAGAAGAGGCCTTGAAGCTGGTGTTACTGGCATTAGAAGATGGTTCTGCCCTCTCAAGGAAAGTTCTGGT
ACTTTTTGTTGTGCAGAGACTAGAACCAAGATTTCCTCAGGCATCAAAAACAAGTATTGGTCATGTTGTGCAACTACTGTATCGAGCTTC
TTGTTTTAAGGAAAATGCCCAGATAATCAGAGAAGTGGAAGTGGACAAGGTCTCCATGCTCTCCAGGGAGCAGGTGGAGGCCATCAAGCA
GCTCTGGCAAGATCCAGGCATCCAGGAGTGTTACGACAGGAGGAGGGAGTACCAGCTGTCGGACTCTGCCAAATATTACCTGACTGACAT
TGACCGCATCGCCACACCATCATTCGTGCCTACCCAACAAGATGTGCTTCGCGTCCGAGTGCCCACCACCGGCATCATTGAGTATCCATT
TGACTTGGAAAACATCATCTTTCGGATGGTGGATGTTGGTGGCCAACGATCGGAAAGACGGAAGTGGATTCACTGCTTTGAGAGTGTCAC
CTCCATTATTTTCTTGGTTGCTCTGAGTGAATATGACCAGGTCCTGGCTGAGTGTGACAACGAGAATCGCATGGAAGAGAGCAAAGCCTT
ATTTAAAACCATCATCACCTACCCCTGGTTTCTGAATTCGTCTGTGATTTTATTCTTGAACAAGAAGGATCTTTTGGAAGAGAAAATCAT
GTACTCTCATCTAATTAGCTATTTCCCAGAATACACAGGACCGAAACAGGATGTCAGAGCTGCCAGAGACTTTATCCTGAAGCTTTACCA
AGATCAGAATCCTGACAAAGAGAAAGTCATCTACTCTCACTTCACATGTGCTACAGATACAGACAATATTCGCTTTGTGTTTGCTGCTGT
CAAAGACACAATTCTACAGCTAAACCTAAGGGAATTCAACCTTGTCTAAAAGCTGCTGCCCACTCCTCCCCTATAACAGAAGATGTGATT
TGCAAACTCCTTGTTTTATTTGCAAGTGCTTCTGACATCACCAGAGCCAGCCCCATGCCAGGAACTAAGGATGTCATGTAGATCGTGGGG
ACAGAGATGGGTGATGGAACTTGGAAGATATTTGAGTTTACCAACATACTTTAAAAGTCCTTACATCCCAAATTGTGTTTATAATTATTT
TCTTGACTTTTGGCTATAAGATTTTGTGTAATTTTTGAATTTGGTGTTTTCTAGAATTTTTAAAAGCCACTTTGATTTAGTTTTAAATAT
GTTTAAAAATAGCGATTAAAATTATGTAAGCAAGGAGCCTGTTAGTTTATAGATCATGCCTTCAAACCTCTAGAGTTAATTTGGGTGACT
TTTTTAAAAATAAGAATGTTAATGGGTTTGAAGCTTTTTATTAAACCTTGTAATTTAGAGACATTTTTAATTGTGTTTCTCACCTCATGC
TGAAGGGTGACTCCTTTAACATGCCACCAAAGATTTTTTTTAAACACTTGGTTCTTTTTGTGTGTTAACTTTCTAAGCCAAATTAATGGA
TATATAAGTATATCTAATTTAGCTTTGCCACAGTTTGATCACCAAGAAGCCAAAGCTGACATAGAGTAAATGGGCTCTAGATAGCATATA
TGTTTTATTGGTGAAAAATGTGTGTGTGTGCACGTGTGTGTGTGTGTACATTTTTACCCCCAATGTATATGACCAGATCTTAAAAATGTA
TGAAATGGCTAGAAGTCCACATTGTTTGACAAATGTTACGTAACCCTGCCAAAGTTCTGATGGCCACCACAGATTTGCTGTTTGAATTAT

>73115_73115_2_RC3H2-GNA14_RC3H2_chr9_125645483_ENST00000357244_GNA14_chr9_80049438_ENST00000341700_length(amino acids)=505AA_BP=253
MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTDIDVLPVNFALLQLVGAQVPDHQSIKLSNLG
ENKHYEVAKKCVEDLALYLKPLSGGKGVASLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL
WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIGHVVQLLYRASCFKENAQIIREVEVDKVSML
SREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERR
KWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRA

--------------------------------------------------------------
>73115_73115_3_RC3H2-GNA14_RC3H2_chr9_125645483_ENST00000373665_GNA14_chr9_80049438_ENST00000341700_length(transcript)=2659nt_BP=1000nt
GTCGCGGCCTTCGCCGCCGCCAACGGGGCTGTCCCTGTAGCTCCCGATGGAGTTTGAGGTCGTGAAACCTCCGCCGAGCTCTGCCCCGGC
GAGACGAGGCGCCTCCGTCGCCAAGCCGCGCCGTCGCGGGGCTCCCGGGAGCGGCCCTTAGCGACCCCGCCCGGGCCCCCTCAGCTTACA
AAACACTACACAGCAAAATAATGATCTGCTAGACTGCTAACCCGAGCATCCAGCTTCCACAATGCCTGTGCAGGCAGCTCAATGGACAGA
ATTTCTGTCCTGTCCAATCTGCTATAATGAATTTGATGAGAATGTGCACAAACCCATCAGTTTAGGTTGTTCACACACTGTTTGCAAGAC
CTGCTTGAATAAACTTCATCGAAAAGCTTGTCCTTTTGACCAGACTGCCATCAACACAGATATTGATGTACTTCCTGTCAACTTCGCACT
TCTCCAGTTAGTTGGAGCCCAGGTACCAGATCATCAGTCAATTAAGTTAAGTAATCTAGGTGAGAATAAACACTATGAGGTTGCAAAGAA
ATGCGTTGAGGATTTGGCACTCTACTTAAAACCACTAAGTGGAGGTAAAGGTGTAGCTAGCTTGAACCAGAGTGCACTGAGCCGTCCAAT
GCAAAGGAAACTGGTGACACTTGTAAACTGTCAACTGGTGGAGGAAGAAGGTCGTGTAAGAGCCATGCGAGCAGCTCGTTCCCTTGGAGA
AAGAACTGTAACAGAACTGATATTACAGCACCAGAACCCTCAGCAGTTGTCTGCCAATCTATGGGCCGCTGTCAGGGCTCGAGGATGCCA
GTTTTTAGGGCCAGCTATGCAAGAAGAGGCCTTGAAGCTGGTGTTACTGGCATTAGAAGATGGTTCTGCCCTCTCAAGGAAAGTTCTGGT
ACTTTTTGTTGTGCAGAGACTAGAACCAAGATTTCCTCAGGCATCAAAAACAAGTATTGGTCATGTTGTGCAACTACTGTATCGAGCTTC
TTGTTTTAAGGAAAATGCCCAGATAATCAGAGAAGTGGAAGTGGACAAGGTCTCCATGCTCTCCAGGGAGCAGGTGGAGGCCATCAAGCA
GCTCTGGCAAGATCCAGGCATCCAGGAGTGTTACGACAGGAGGAGGGAGTACCAGCTGTCGGACTCTGCCAAATATTACCTGACTGACAT
TGACCGCATCGCCACACCATCATTCGTGCCTACCCAACAAGATGTGCTTCGCGTCCGAGTGCCCACCACCGGCATCATTGAGTATCCATT
TGACTTGGAAAACATCATCTTTCGGATGGTGGATGTTGGTGGCCAACGATCGGAAAGACGGAAGTGGATTCACTGCTTTGAGAGTGTCAC
CTCCATTATTTTCTTGGTTGCTCTGAGTGAATATGACCAGGTCCTGGCTGAGTGTGACAACGAGAATCGCATGGAAGAGAGCAAAGCCTT
ATTTAAAACCATCATCACCTACCCCTGGTTTCTGAATTCGTCTGTGATTTTATTCTTGAACAAGAAGGATCTTTTGGAAGAGAAAATCAT
GTACTCTCATCTAATTAGCTATTTCCCAGAATACACAGGACCGAAACAGGATGTCAGAGCTGCCAGAGACTTTATCCTGAAGCTTTACCA
AGATCAGAATCCTGACAAAGAGAAAGTCATCTACTCTCACTTCACATGTGCTACAGATACAGACAATATTCGCTTTGTGTTTGCTGCTGT
CAAAGACACAATTCTACAGCTAAACCTAAGGGAATTCAACCTTGTCTAAAAGCTGCTGCCCACTCCTCCCCTATAACAGAAGATGTGATT
TGCAAACTCCTTGTTTTATTTGCAAGTGCTTCTGACATCACCAGAGCCAGCCCCATGCCAGGAACTAAGGATGTCATGTAGATCGTGGGG
ACAGAGATGGGTGATGGAACTTGGAAGATATTTGAGTTTACCAACATACTTTAAAAGTCCTTACATCCCAAATTGTGTTTATAATTATTT
TCTTGACTTTTGGCTATAAGATTTTGTGTAATTTTTGAATTTGGTGTTTTCTAGAATTTTTAAAAGCCACTTTGATTTAGTTTTAAATAT
GTTTAAAAATAGCGATTAAAATTATGTAAGCAAGGAGCCTGTTAGTTTATAGATCATGCCTTCAAACCTCTAGAGTTAATTTGGGTGACT
TTTTTAAAAATAAGAATGTTAATGGGTTTGAAGCTTTTTATTAAACCTTGTAATTTAGAGACATTTTTAATTGTGTTTCTCACCTCATGC
TGAAGGGTGACTCCTTTAACATGCCACCAAAGATTTTTTTTAAACACTTGGTTCTTTTTGTGTGTTAACTTTCTAAGCCAAATTAATGGA
TATATAAGTATATCTAATTTAGCTTTGCCACAGTTTGATCACCAAGAAGCCAAAGCTGACATAGAGTAAATGGGCTCTAGATAGCATATA
TGTTTTATTGGTGAAAAATGTGTGTGTGTGCACGTGTGTGTGTGTGTACATTTTTACCCCCAATGTATATGACCAGATCTTAAAAATGTA
TGAAATGGCTAGAAGTCCACATTGTTTGACAAATGTTACGTAACCCTGCCAAAGTTCTGATGGCCACCACAGATTTGCTGTTTGAATTAT

>73115_73115_3_RC3H2-GNA14_RC3H2_chr9_125645483_ENST00000373665_GNA14_chr9_80049438_ENST00000341700_length(amino acids)=505AA_BP=253
MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTDIDVLPVNFALLQLVGAQVPDHQSIKLSNLG
ENKHYEVAKKCVEDLALYLKPLSGGKGVASLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL
WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIGHVVQLLYRASCFKENAQIIREVEVDKVSML
SREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERR
KWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRA

--------------------------------------------------------------
>73115_73115_4_RC3H2-GNA14_RC3H2_chr9_125645483_ENST00000373670_GNA14_chr9_80049438_ENST00000341700_length(transcript)=3019nt_BP=1360nt
AGCCAAGTCTTGTCAGAGATTTCCTCTTTCAGGTGGCAAAGCTGTTTTCTTCACACTTGAGTCTCTACAATATTGTTTGGATCAGTAGTT
TCCAAAGTTCATTAACTCCTGGCCATACTTTATTATGTTTTGGGGTACTGGTTATCCAAGGGAAACACTTTTTTAAACAACAAAACAAAA
AAACCGCCCAGCAGTCCAAAGTAATTTGTGTTCCTAAAAATGGAATATGGAAAGTTAATTTGCTTGTTTGATGTGGTCGTTGAGAAAAAT
ACATAAAAGCTTTGATGTTTATTATGTGAGCAACCAATATAAATACAGTTTAGTTGAAAGGAACACTATTAAGGTATTGTTTCCAGGCAG
AATTTCAGAAATGTAATTAATTCAGCAAATAGGTTTTTTAAAAAAGACATCCAAAGGTTATAAAATTATTTAGAAGTATTTTAGGTCTGA
AGCTGTAATAGTTGACTTAAGCAATTAACTCTTCAAAGGTGAATGATGAATATGTGGTTAATTCATACTTTTGTCCATTTCTAGCTTACA
AAACACTACACAGCAAAATAATGATCTGCTAGACTGCTAACCCGAGCATCCAGCTTCCACAATGCCTGTGCAGGCAGCTCAATGGACAGA
ATTTCTGTCCTGTCCAATCTGCTATAATGAATTTGATGAGAATGTGCACAAACCCATCAGTTTAGGTTGTTCACACACTGTTTGCAAGAC
CTGCTTGAATAAACTTCATCGAAAAGCTTGTCCTTTTGACCAGACTGCCATCAACACAGATATTGATGTACTTCCTGTCAACTTCGCACT
TCTCCAGTTAGTTGGAGCCCAGGTACCAGATCATCAGTCAATTAAGTTAAGTAATCTAGGTGAGAATAAACACTATGAGGTTGCAAAGAA
ATGCGTTGAGGATTTGGCACTCTACTTAAAACCACTAAGTGGAGGTAAAGGTGTAGCTAGCTTGAACCAGAGTGCACTGAGCCGTCCAAT
GCAAAGGAAACTGGTGACACTTGTAAACTGTCAACTGGTGGAGGAAGAAGGTCGTGTAAGAGCCATGCGAGCAGCTCGTTCCCTTGGAGA
AAGAACTGTAACAGAACTGATATTACAGCACCAGAACCCTCAGCAGTTGTCTGCCAATCTATGGGCCGCTGTCAGGGCTCGAGGATGCCA
GTTTTTAGGGCCAGCTATGCAAGAAGAGGCCTTGAAGCTGGTGTTACTGGCATTAGAAGATGGTTCTGCCCTCTCAAGGAAAGTTCTGGT
ACTTTTTGTTGTGCAGAGACTAGAACCAAGATTTCCTCAGGCATCAAAAACAAGTATTGGTCATGTTGTGCAACTACTGTATCGAGCTTC
TTGTTTTAAGGAAAATGCCCAGATAATCAGAGAAGTGGAAGTGGACAAGGTCTCCATGCTCTCCAGGGAGCAGGTGGAGGCCATCAAGCA
GCTCTGGCAAGATCCAGGCATCCAGGAGTGTTACGACAGGAGGAGGGAGTACCAGCTGTCGGACTCTGCCAAATATTACCTGACTGACAT
TGACCGCATCGCCACACCATCATTCGTGCCTACCCAACAAGATGTGCTTCGCGTCCGAGTGCCCACCACCGGCATCATTGAGTATCCATT
TGACTTGGAAAACATCATCTTTCGGATGGTGGATGTTGGTGGCCAACGATCGGAAAGACGGAAGTGGATTCACTGCTTTGAGAGTGTCAC
CTCCATTATTTTCTTGGTTGCTCTGAGTGAATATGACCAGGTCCTGGCTGAGTGTGACAACGAGAATCGCATGGAAGAGAGCAAAGCCTT
ATTTAAAACCATCATCACCTACCCCTGGTTTCTGAATTCGTCTGTGATTTTATTCTTGAACAAGAAGGATCTTTTGGAAGAGAAAATCAT
GTACTCTCATCTAATTAGCTATTTCCCAGAATACACAGGACCGAAACAGGATGTCAGAGCTGCCAGAGACTTTATCCTGAAGCTTTACCA
AGATCAGAATCCTGACAAAGAGAAAGTCATCTACTCTCACTTCACATGTGCTACAGATACAGACAATATTCGCTTTGTGTTTGCTGCTGT
CAAAGACACAATTCTACAGCTAAACCTAAGGGAATTCAACCTTGTCTAAAAGCTGCTGCCCACTCCTCCCCTATAACAGAAGATGTGATT
TGCAAACTCCTTGTTTTATTTGCAAGTGCTTCTGACATCACCAGAGCCAGCCCCATGCCAGGAACTAAGGATGTCATGTAGATCGTGGGG
ACAGAGATGGGTGATGGAACTTGGAAGATATTTGAGTTTACCAACATACTTTAAAAGTCCTTACATCCCAAATTGTGTTTATAATTATTT
TCTTGACTTTTGGCTATAAGATTTTGTGTAATTTTTGAATTTGGTGTTTTCTAGAATTTTTAAAAGCCACTTTGATTTAGTTTTAAATAT
GTTTAAAAATAGCGATTAAAATTATGTAAGCAAGGAGCCTGTTAGTTTATAGATCATGCCTTCAAACCTCTAGAGTTAATTTGGGTGACT
TTTTTAAAAATAAGAATGTTAATGGGTTTGAAGCTTTTTATTAAACCTTGTAATTTAGAGACATTTTTAATTGTGTTTCTCACCTCATGC
TGAAGGGTGACTCCTTTAACATGCCACCAAAGATTTTTTTTAAACACTTGGTTCTTTTTGTGTGTTAACTTTCTAAGCCAAATTAATGGA
TATATAAGTATATCTAATTTAGCTTTGCCACAGTTTGATCACCAAGAAGCCAAAGCTGACATAGAGTAAATGGGCTCTAGATAGCATATA
TGTTTTATTGGTGAAAAATGTGTGTGTGTGCACGTGTGTGTGTGTGTACATTTTTACCCCCAATGTATATGACCAGATCTTAAAAATGTA
TGAAATGGCTAGAAGTCCACATTGTTTGACAAATGTTACGTAACCCTGCCAAAGTTCTGATGGCCACCACAGATTTGCTGTTTGAATTAT

>73115_73115_4_RC3H2-GNA14_RC3H2_chr9_125645483_ENST00000373670_GNA14_chr9_80049438_ENST00000341700_length(amino acids)=505AA_BP=253
MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTDIDVLPVNFALLQLVGAQVPDHQSIKLSNLG
ENKHYEVAKKCVEDLALYLKPLSGGKGVASLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL
WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIGHVVQLLYRASCFKENAQIIREVEVDKVSML
SREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERR
KWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRA

--------------------------------------------------------------
>73115_73115_5_RC3H2-GNA14_RC3H2_chr9_125645483_ENST00000423239_GNA14_chr9_80049438_ENST00000341700_length(transcript)=2717nt_BP=1058nt
CCGTGGTGAGGAGGAGGAGGAGGAGGAGGCGGAGGTGGAGGGAGGAGGAGGAGGCCCCGTCGCGGCCTTCGCCGCCGCCAACGGGGCTGT
CCCTGTAGCTCCCGATGGAGTTTGAGGTCGTGAAACCTCCGCCGAGCTCTGCCCCGGCGAGACGAGGCGCCTCCGTCGCCAAGCCGCGCC
GTCGCGGGGCTCCCGGGAGCGGCCCTTAGCGACCCCGCCCGGGCCCCCTCAGCTTACAAAACACTACACAGCAAAATAATGATCTGCTAG
ACTGCTAACCCGAGCATCCAGCTTCCACAATGCCTGTGCAGGCAGCTCAATGGACAGAATTTCTGTCCTGTCCAATCTGCTATAATGAAT
TTGATGAGAATGTGCACAAACCCATCAGTTTAGGTTGTTCACACACTGTTTGCAAGACCTGCTTGAATAAACTTCATCGAAAAGCTTGTC
CTTTTGACCAGACTGCCATCAACACAGATATTGATGTACTTCCTGTCAACTTCGCACTTCTCCAGTTAGTTGGAGCCCAGGTACCAGATC
ATCAGTCAATTAAGTTAAGTAATCTAGGTGAGAATAAACACTATGAGGTTGCAAAGAAATGCGTTGAGGATTTGGCACTCTACTTAAAAC
CACTAAGTGGAGGTAAAGGTGTAGCTAGCTTGAACCAGAGTGCACTGAGCCGTCCAATGCAAAGGAAACTGGTGACACTTGTAAACTGTC
AACTGGTGGAGGAAGAAGGTCGTGTAAGAGCCATGCGAGCAGCTCGTTCCCTTGGAGAAAGAACTGTAACAGAACTGATATTACAGCACC
AGAACCCTCAGCAGTTGTCTGCCAATCTATGGGCCGCTGTCAGGGCTCGAGGATGCCAGTTTTTAGGGCCAGCTATGCAAGAAGAGGCCT
TGAAGCTGGTGTTACTGGCATTAGAAGATGGTTCTGCCCTCTCAAGGAAAGTTCTGGTACTTTTTGTTGTGCAGAGACTAGAACCAAGAT
TTCCTCAGGCATCAAAAACAAGTATTGGTCATGTTGTGCAACTACTGTATCGAGCTTCTTGTTTTAAGGAAAATGCCCAGATAATCAGAG
AAGTGGAAGTGGACAAGGTCTCCATGCTCTCCAGGGAGCAGGTGGAGGCCATCAAGCAGCTCTGGCAAGATCCAGGCATCCAGGAGTGTT
ACGACAGGAGGAGGGAGTACCAGCTGTCGGACTCTGCCAAATATTACCTGACTGACATTGACCGCATCGCCACACCATCATTCGTGCCTA
CCCAACAAGATGTGCTTCGCGTCCGAGTGCCCACCACCGGCATCATTGAGTATCCATTTGACTTGGAAAACATCATCTTTCGGATGGTGG
ATGTTGGTGGCCAACGATCGGAAAGACGGAAGTGGATTCACTGCTTTGAGAGTGTCACCTCCATTATTTTCTTGGTTGCTCTGAGTGAAT
ATGACCAGGTCCTGGCTGAGTGTGACAACGAGAATCGCATGGAAGAGAGCAAAGCCTTATTTAAAACCATCATCACCTACCCCTGGTTTC
TGAATTCGTCTGTGATTTTATTCTTGAACAAGAAGGATCTTTTGGAAGAGAAAATCATGTACTCTCATCTAATTAGCTATTTCCCAGAAT
ACACAGGACCGAAACAGGATGTCAGAGCTGCCAGAGACTTTATCCTGAAGCTTTACCAAGATCAGAATCCTGACAAAGAGAAAGTCATCT
ACTCTCACTTCACATGTGCTACAGATACAGACAATATTCGCTTTGTGTTTGCTGCTGTCAAAGACACAATTCTACAGCTAAACCTAAGGG
AATTCAACCTTGTCTAAAAGCTGCTGCCCACTCCTCCCCTATAACAGAAGATGTGATTTGCAAACTCCTTGTTTTATTTGCAAGTGCTTC
TGACATCACCAGAGCCAGCCCCATGCCAGGAACTAAGGATGTCATGTAGATCGTGGGGACAGAGATGGGTGATGGAACTTGGAAGATATT
TGAGTTTACCAACATACTTTAAAAGTCCTTACATCCCAAATTGTGTTTATAATTATTTTCTTGACTTTTGGCTATAAGATTTTGTGTAAT
TTTTGAATTTGGTGTTTTCTAGAATTTTTAAAAGCCACTTTGATTTAGTTTTAAATATGTTTAAAAATAGCGATTAAAATTATGTAAGCA
AGGAGCCTGTTAGTTTATAGATCATGCCTTCAAACCTCTAGAGTTAATTTGGGTGACTTTTTTAAAAATAAGAATGTTAATGGGTTTGAA
GCTTTTTATTAAACCTTGTAATTTAGAGACATTTTTAATTGTGTTTCTCACCTCATGCTGAAGGGTGACTCCTTTAACATGCCACCAAAG
ATTTTTTTTAAACACTTGGTTCTTTTTGTGTGTTAACTTTCTAAGCCAAATTAATGGATATATAAGTATATCTAATTTAGCTTTGCCACA
GTTTGATCACCAAGAAGCCAAAGCTGACATAGAGTAAATGGGCTCTAGATAGCATATATGTTTTATTGGTGAAAAATGTGTGTGTGTGCA
CGTGTGTGTGTGTGTACATTTTTACCCCCAATGTATATGACCAGATCTTAAAAATGTATGAAATGGCTAGAAGTCCACATTGTTTGACAA
ATGTTACGTAACCCTGCCAAAGTTCTGATGGCCACCACAGATTTGCTGTTTGAATTATGTATGCTGTGCCTTTCTGAGGAGGCTAAGAAT

>73115_73115_5_RC3H2-GNA14_RC3H2_chr9_125645483_ENST00000423239_GNA14_chr9_80049438_ENST00000341700_length(amino acids)=505AA_BP=253
MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTDIDVLPVNFALLQLVGAQVPDHQSIKLSNLG
ENKHYEVAKKCVEDLALYLKPLSGGKGVASLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL
WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIGHVVQLLYRASCFKENAQIIREVEVDKVSML
SREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERR
KWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RC3H2-GNA14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RC3H2-GNA14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RC3H2-GNA14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource