FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:RCOR1-PPP2R5C (FusionGDB2 ID:73329)

Fusion Gene Summary for RCOR1-PPP2R5C

check button Fusion gene summary
Fusion gene informationFusion gene name: RCOR1-PPP2R5C
Fusion gene ID: 73329
HgeneTgene
Gene symbol

RCOR1

PPP2R5C

Gene ID

23186

5527

Gene nameREST corepressor 1protein phosphatase 2 regulatory subunit B'gamma
SynonymsCOREST|RCORB56G|B56gamma|PR61G
Cytomap

14q32.31-q32.32

14q32.31

Type of geneprotein-codingprotein-coding
DescriptionREST corepressor 1serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoformB' alpha regulatory subunitPP2A B subunit isoform B'-gammaPP2A B subunit isoform B56-gammaPP2A B subunit isoform PR61-gammaPP2A B subunit isoform R5-gammaprotein phosphat
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000262241, ENST00000570597, 
ENST00000328724, ENST00000334743, 
ENST00000350249, ENST00000445439, 
ENST00000554442, ENST00000556068, 
ENST00000556260, ENST00000556946, 
ENST00000557095, ENST00000557714, 
ENST00000422945, 
Fusion gene scores* DoF score10 X 9 X 10=90015 X 17 X 10=2550
# samples 2022
** MAII scorelog2(20/900*10)=-2.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(22/2550*10)=-3.53492181822156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RCOR1 [Title/Abstract] AND PPP2R5C [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRCOR1(103148315)-PPP2R5C(102323023), # samples:3
RCOR1(103059662)-PPP2R5C(102391478), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRCOR1

GO:0045892

negative regulation of transcription, DNA-templated

10449787

HgeneRCOR1

GO:0070933

histone H4 deacetylation

17555596

TgenePPP2R5C

GO:0008285

negative regulation of cell proliferation

17245430


check buttonFusion gene breakpoints across RCOR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PPP2R5C (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ACCTCGA-OR-A5J7-01ARCOR1chr14

103148315

-PPP2R5Cchr14

102323023

+
ChimerDB4ACCTCGA-OR-A5J7-01ARCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
ChimerDB4OVTCGA-13-1410-01ARCOR1chr14

103059662

-PPP2R5Cchr14

102391478

+
ChimerDB4OVTCGA-13-1410-01ARCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
ChimerDB4OVTCGA-13-1410RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+


Top

Fusion Gene ORF analysis for RCOR1-PPP2R5C

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000262241ENST00000328724RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000262241ENST00000328724RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000262241ENST00000328724RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000262241ENST00000334743RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000262241ENST00000334743RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000262241ENST00000334743RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000262241ENST00000350249RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000262241ENST00000350249RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000262241ENST00000350249RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000262241ENST00000445439RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000262241ENST00000445439RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000262241ENST00000445439RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000262241ENST00000554442RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000262241ENST00000554442RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000262241ENST00000554442RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000262241ENST00000556068RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000262241ENST00000556068RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000262241ENST00000556068RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000262241ENST00000556260RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000262241ENST00000556260RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000262241ENST00000556260RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000262241ENST00000556946RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000262241ENST00000556946RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000262241ENST00000556946RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000262241ENST00000557095RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000262241ENST00000557095RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000262241ENST00000557095RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000262241ENST00000557714RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000262241ENST00000557714RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000262241ENST00000557714RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000570597ENST00000328724RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000570597ENST00000328724RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000570597ENST00000328724RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000570597ENST00000334743RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000570597ENST00000334743RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000570597ENST00000334743RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000570597ENST00000350249RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000570597ENST00000350249RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000570597ENST00000350249RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000570597ENST00000445439RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000570597ENST00000445439RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000570597ENST00000445439RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000570597ENST00000554442RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000570597ENST00000554442RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000570597ENST00000554442RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000570597ENST00000556068RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000570597ENST00000556068RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000570597ENST00000556068RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000570597ENST00000556260RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000570597ENST00000556260RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000570597ENST00000556260RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000570597ENST00000556946RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000570597ENST00000556946RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000570597ENST00000556946RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000570597ENST00000557095RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000570597ENST00000557095RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000570597ENST00000557095RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
5CDS-intronENST00000570597ENST00000557714RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
5CDS-intronENST00000570597ENST00000557714RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
5CDS-intronENST00000570597ENST00000557714RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
In-frameENST00000262241ENST00000422945RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
In-frameENST00000262241ENST00000422945RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
In-frameENST00000262241ENST00000422945RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+
In-frameENST00000570597ENST00000422945RCOR1chr14

103148315

+PPP2R5Cchr14

102323023

+
In-frameENST00000570597ENST00000422945RCOR1chr14

103059662

+PPP2R5Cchr14

102391478

+
In-frameENST00000570597ENST00000422945RCOR1chr14

103059662

+PPP2R5Cchr14

102391477

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000262241RCOR1chr14103148315+ENST00000422945PPP2R5Cchr14102323023+4869671252151708
ENST00000570597RCOR1chr14103148315+ENST00000422945PPP2R5Cchr14102323023+463443601916638
ENST00000262241RCOR1chr14103059662+ENST00000422945PPP2R5Cchr14102391478+3436587863177228
ENST00000570597RCOR1chr14103059662+ENST00000422945PPP2R5Cchr14102391478+32013526282209
ENST00000262241RCOR1chr14103059662+ENST00000422945PPP2R5Cchr14102391477+3436587863177228
ENST00000570597RCOR1chr14103059662+ENST00000422945PPP2R5Cchr14102391477+32013526282209

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000262241ENST00000422945RCOR1chr14103148315+PPP2R5Cchr14102323023+0.0008385660.9991615
ENST00000570597ENST00000422945RCOR1chr14103148315+PPP2R5Cchr14102323023+0.0003348230.99966514
ENST00000262241ENST00000422945RCOR1chr14103059662+PPP2R5Cchr14102391478+0.0131008920.98689914
ENST00000570597ENST00000422945RCOR1chr14103059662+PPP2R5Cchr14102391478+0.0120534270.98794657
ENST00000262241ENST00000422945RCOR1chr14103059662+PPP2R5Cchr14102391477+0.0131008920.98689914
ENST00000570597ENST00000422945RCOR1chr14103059662+PPP2R5Cchr14102391477+0.0120534270.98794657

Top

Fusion Genomic Features for RCOR1-PPP2R5C


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RCOR1chr14103148315+PPP2R5Cchr14102323022+2.26E-050.99997735
RCOR1chr14103059662+PPP2R5Cchr14102391477+1.13E-091
RCOR1chr14103059662+PPP2R5Cchr14102391477+1.13E-091
RCOR1chr14103148315+PPP2R5Cchr14102323022+2.26E-050.99997735
RCOR1chr14103059662+PPP2R5Cchr14102391477+1.13E-091
RCOR1chr14103059662+PPP2R5Cchr14102391477+1.13E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for RCOR1-PPP2R5C


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:103148315/chr14:102323023)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRCOR1chr14:103059662chr14:102391477ENST00000570597+21221_77117483.0Compositional biasNote=Ala-rich
HgeneRCOR1chr14:103059662chr14:102391478ENST00000570597+21221_77117483.0Compositional biasNote=Ala-rich
HgeneRCOR1chr14:103148315chr14:102323023ENST00000570597+31221_77145483.0Compositional biasNote=Ala-rich
TgenePPP2R5Cchr14:103059662chr14:102391477ENST00000445439012416_4220450.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103059662chr14:102391478ENST00000445439012416_4220450.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103148315chr14:102323023ENST00000328724215416_42286541.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103148315chr14:102323023ENST00000334743014416_42231525.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103148315chr14:102323023ENST00000350249013416_42231486.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103148315chr14:102323023ENST00000422945216416_42262556.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103148315chr14:102323023ENST00000445439012416_42231450.0MotifNuclear localization signal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRCOR1chr14:103059662chr14:102391477ENST00000570597+212244_273117483.0Coiled coilOntology_term=ECO:0000255
HgeneRCOR1chr14:103059662chr14:102391477ENST00000570597+212334_369117483.0Coiled coilOntology_term=ECO:0000255
HgeneRCOR1chr14:103059662chr14:102391478ENST00000570597+212244_273117483.0Coiled coilOntology_term=ECO:0000255
HgeneRCOR1chr14:103059662chr14:102391478ENST00000570597+212334_369117483.0Coiled coilOntology_term=ECO:0000255
HgeneRCOR1chr14:103148315chr14:102323023ENST00000570597+312244_273145483.0Coiled coilOntology_term=ECO:0000255
HgeneRCOR1chr14:103148315chr14:102323023ENST00000570597+312334_369145483.0Coiled coilOntology_term=ECO:0000255
HgeneRCOR1chr14:103059662chr14:102391477ENST00000570597+212103_189117483.0DomainELM2
HgeneRCOR1chr14:103059662chr14:102391477ENST00000570597+212190_241117483.0DomainSANT 1
HgeneRCOR1chr14:103059662chr14:102391477ENST00000570597+212381_432117483.0DomainSANT 2
HgeneRCOR1chr14:103059662chr14:102391478ENST00000570597+212103_189117483.0DomainELM2
HgeneRCOR1chr14:103059662chr14:102391478ENST00000570597+212190_241117483.0DomainSANT 1
HgeneRCOR1chr14:103059662chr14:102391478ENST00000570597+212381_432117483.0DomainSANT 2
HgeneRCOR1chr14:103148315chr14:102323023ENST00000570597+312103_189145483.0DomainELM2
HgeneRCOR1chr14:103148315chr14:102323023ENST00000570597+312190_241145483.0DomainSANT 1
HgeneRCOR1chr14:103148315chr14:102323023ENST00000570597+312381_432145483.0DomainSANT 2
TgenePPP2R5Cchr14:103059662chr14:102391477ENST000003287241315416_422497541.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103059662chr14:102391477ENST000003347431214416_422481525.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103059662chr14:102391477ENST000003502491113416_422442486.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103059662chr14:102391477ENST000004229451416416_422512556.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103059662chr14:102391478ENST000003287241315416_422497541.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103059662chr14:102391478ENST000003347431214416_422481525.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103059662chr14:102391478ENST000003502491113416_422442486.0MotifNuclear localization signal
TgenePPP2R5Cchr14:103059662chr14:102391478ENST000004229451416416_422512556.0MotifNuclear localization signal


Top

Fusion Gene Sequence for RCOR1-PPP2R5C


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>73329_73329_1_RCOR1-PPP2R5C_RCOR1_chr14_103059662_ENST00000262241_PPP2R5C_chr14_102391477_ENST00000422945_length(transcript)=3436nt_BP=587nt
GTGAGGGCGGCGATGAGAGCGAAAGTTGCGCTCGGCTCGTCGCTGGGGGCTTGAAGCGGCTCCGCGCTCTGCCCGTTTGGGCCTCCCCCG
ACTCGGACTCGCGCCCGTGGGCTCCCGCCGCGCCCGCCCGGCCCCGCGCCGGCCCCGCGCCCCCTCCCCCGTCTCGGCGCCCCCTCCTCA
GGAGCCGCGGGTCCCCGCCACTTTCGCACGGCCCCGGCCCCCGCCGATGCCGGCCATGGTGGAGAAGGGCCCCGAGGTCTCAGGGAAGCG
GAGAGGGAGGAACAACGCGGCCGCCTCCGCCTCCGCCGCCGCCGCCTCCGCCGCCGCCTCGGCCGCCTGCGCCTCGCCAGCCGCCACTGC
CGCCTCGGGCGCCGCCGCCTCCTCAGCCTCGGCCGCCGCCGCCTCAGCCGCCGCCGCCCCCAATAATGGCCAGAATAAAAGTTTGGCGGC
GGCGGCGCCCAATGGCAACAGCAGCAGCAACTCCTGGGAGGAAGGCAGCTCGGGCTCGTCCAGCGACGAGGAGCACGGTGGCGGTGGCAT
GAGGGTCGGACCCCAGTACCAGGCGGTGGTGCCCGACTTCGACCCCGGCACAGAAAGATCCGAAGAAGGACCGTCCTCTTGCACGCCGCA
AGTCCGAGCTGCCTCAGGACCCCCACACCAAGAAAGCCTTGGAAGCTCACTGCAGGGCCGATGAGCTGGCCTCCCAGGACGGCCGCTAGC
CTCCGGGGCGCCGCGTCGGGGCCGGGCCCGCCAGTTCTTTTCCGGATTCTGTAGAAAATACATACTTCCTGTGCCATACCAATCAGTTAC
ACTCAAAGCTTTCTTGGACCCCGTTCCGTAGGCAATAACGTGCGTCCGCCTCAGCGCGAGATTAGGAGTTCAAACAATGGTGACTTCCCA
GAGCCCGCTGGCAGAGCCGCGGGTTGACGACGGTGTCCTCGCAGTGTCGCCGCCACCCCAGCGTAGTCCAAGTCAGACTATTTCACAAAG
TCAGAGCGATAGGAAAGCACCCTGCCCTTCATCTTCATGTTCTCCCAAATGGAACTTAGGATCTTTTAACATAGGTGGTTCTGTGATAAC
ATCAGTGTTTTCCAAATCAAAGGAACGCTTTAAAAAATAGGACCTATTTTTTAAGACTTTACAGCCTTTGAAATGGTTTCCACGTGATTG
TTACGCCAGCAGTTCTCGTTTTGTTTGTTTTTCAATCTCAGTGAAATGGCTCTTTGCTTTCGAGTTCTCACGCAACGTACTGGGCAAATG
ACAATCCTCAGCCGCTGGTATTTTCTAAGGGGTCTCTTCACTTTGATGAGTGACATGAACACCGTGTCTCCTTCTCTTGTGTGTACCTAA
AGCCATATTTCCAAGTCTGTGGTACTCCAGGATTCCAGGAGTAAGCCTGTAGAAGAGATTTATTTTAAAAGAGATTGCTCTGAAATTTAT
CTTAAAAGAGCTTGCTCTGTCTACCTTGACAGAAATTGGAGTTTTAAAATTATGTGTTAATATTTTTATTTGCAGATTTCGTTTCCGTCA
ACTTAAACATTGTTGCCCTTCAACAAGGCTCTTGAATTAATAAAATTATAGTCTCTAAGAATTCCACATTTTATGGAAAGTTAGAGCAAA
ATCATTTTGAGTTAAGCCAGTTCTTAGCCTAATGCAAACTGCAGCGCCTTTAAGCATAAAGTAACACAACAGCATTGCACGGGGCCGGCA
CTGCCGCTGCCTTCACTGAAGGCTGCAGTGCTGTTCTGAGAGCTTGGAGGAGGCACCAGCGAGGATGACGTTTAGTGGAGCTCTTTCTGT
TGAAAAGAGCTCACGTTATCAACACCTTGTAAGGAAAATACAGTGTCTGAGTTTTCATCGGTCTTCACATGCTGCTATATATTCCACAGA
GTTCCTTGCATGTACTGAGCTTTTGTTTTAGATGGAATAGCACAAGGAGAAAAATCTTTAAACTTAGTGCTTTGTCTATTCTTTATTTCT
CTCAGGGTGGCCAGTATTTTGACTTATTTATCCTGCTTGAAAGCTACTTGAGATGTGTACTGCTATTCTAAACACGTGATCTAGTTTCTT
TCATCTCTGGCATAAGATTATATAACTTAATGTTAAGTGTCTTGAGGCATAAAAGACAAAATGTGGCTTATTTTAGGATCTGTTTTTTCA
TCGAGGTCTCGGGTATCCTTTCAAAGATAGTGAGAAGCAGACACTGCTCCTTGTGCAGCTCTGGTACCTCCTGCCCACTGCTGTCACTTC
AAGCCACTGGCAATGCTTCTGTCCTCGTGTCTTGGAGGAAAATCACCTGGGGGGAGGGGACTTCTTGTGGTAAGAGCAAGTGCAGGTATG
AAATGCGAAGATTGCCCCAGCTAAAAGTGGACAAGTCCGCTTTGTGAGATGAATACTTCCTGAGAAACTTGACAAGTATCTCTCCATTTT
ACCATTATGAAAACTATCATTAAAAAAAACAGTTTAGATGCCTTCTCCTTTTGAGGGAAAAAGGGTGCTTTTTATTGTATAAAGCAGCGT
CTTATGTATTTTGATATACCATTGTTTGAACTTCCGTCTTTAGCTGATAGATTCTCAAATATCCTTGATTTTGGATGTTCAGTATGTTTG
TGAGAGAGGTTTCTGGGAAGACTCTCTTTTTGCCCTCGGGAAAAAGCAAAATATCAATGTTTGGGTGACTGTGTAAAGCTCAGTGTGTAA
GAACATCTTTTTGTCTAGGTTTTCTTTCTGCTCTTTATTGAAGACAAACACTCACCAAAAAGAAAAATAAAAGTTTTCAGAGAAACTAAT
TTTCTTTGGCAAGAGTATTACTTAATATTTTGGCCTCCTAAAGTTTCCCTAGTTAGTACTCGGACTCCTGTGCTAATTGTCAGCTTACAT
ATCATTGTATAGAGACTGTTTATTCTGTACCAAACTGATTTCAAAAGTACTACATTGAAAATAAACCGGTGACTGTTTTTCTTCATAAAG
TTCTGCGTTTGGCATCTTCACTCTTTCCAAAATGTATCTGTACATCAGAAATGTCACTATTCCAAGTGTCTTTTTAGTGTGGCTTTAGTA
TGGCTTCCTTTTAATATTGTACATACATTGTATCTTTGTTTTATGGTAATAAGTAATAAAAATGTAGACTTCATATTTTGTACAAAATGT
CCTATGTACAGAATAAAAAAGTTCATAGAAACAGCAAATATAGGTAAGTGGCACAATTATTTTTCTTTAGAAAATATCTGTAACTTTATG
CATTAGTGAAATGTTAAGTACCGACATATTTTTTAACATTTTGTAATTCAAAACTTTTTGTTTTGACATTGTTTATGAAGAGAAACTTCA
TACACTTGCCATTTAATATGCTCTTTTATCTAATTTTCAAAAACTCTAAAAAACGGTGTATCATATGGACTAAATAAAGAACATGTGAAT

>73329_73329_1_RCOR1-PPP2R5C_RCOR1_chr14_103059662_ENST00000262241_PPP2R5C_chr14_102391477_ENST00000422945_length(amino acids)=228AA_BP=1
MRRTHVIAYGTGSKKALSVTDWYGTGSMYFLQNPEKNWRARPRRGAPEASGRPGRPAHRPCSELPRLSWCGGPEAARTCGVQEDGPSSDL
SVPGSKSGTTAWYWGPTLMPPPPCSSSLDEPELPSSQELLLLLPLGAAAAKLLFWPLLGAAAAEAAAAEAEEAAAPEAAVAAGEAQAAEA

--------------------------------------------------------------
>73329_73329_2_RCOR1-PPP2R5C_RCOR1_chr14_103059662_ENST00000262241_PPP2R5C_chr14_102391478_ENST00000422945_length(transcript)=3436nt_BP=587nt
GTGAGGGCGGCGATGAGAGCGAAAGTTGCGCTCGGCTCGTCGCTGGGGGCTTGAAGCGGCTCCGCGCTCTGCCCGTTTGGGCCTCCCCCG
ACTCGGACTCGCGCCCGTGGGCTCCCGCCGCGCCCGCCCGGCCCCGCGCCGGCCCCGCGCCCCCTCCCCCGTCTCGGCGCCCCCTCCTCA
GGAGCCGCGGGTCCCCGCCACTTTCGCACGGCCCCGGCCCCCGCCGATGCCGGCCATGGTGGAGAAGGGCCCCGAGGTCTCAGGGAAGCG
GAGAGGGAGGAACAACGCGGCCGCCTCCGCCTCCGCCGCCGCCGCCTCCGCCGCCGCCTCGGCCGCCTGCGCCTCGCCAGCCGCCACTGC
CGCCTCGGGCGCCGCCGCCTCCTCAGCCTCGGCCGCCGCCGCCTCAGCCGCCGCCGCCCCCAATAATGGCCAGAATAAAAGTTTGGCGGC
GGCGGCGCCCAATGGCAACAGCAGCAGCAACTCCTGGGAGGAAGGCAGCTCGGGCTCGTCCAGCGACGAGGAGCACGGTGGCGGTGGCAT
GAGGGTCGGACCCCAGTACCAGGCGGTGGTGCCCGACTTCGACCCCGGCACAGAAAGATCCGAAGAAGGACCGTCCTCTTGCACGCCGCA
AGTCCGAGCTGCCTCAGGACCCCCACACCAAGAAAGCCTTGGAAGCTCACTGCAGGGCCGATGAGCTGGCCTCCCAGGACGGCCGCTAGC
CTCCGGGGCGCCGCGTCGGGGCCGGGCCCGCCAGTTCTTTTCCGGATTCTGTAGAAAATACATACTTCCTGTGCCATACCAATCAGTTAC
ACTCAAAGCTTTCTTGGACCCCGTTCCGTAGGCAATAACGTGCGTCCGCCTCAGCGCGAGATTAGGAGTTCAAACAATGGTGACTTCCCA
GAGCCCGCTGGCAGAGCCGCGGGTTGACGACGGTGTCCTCGCAGTGTCGCCGCCACCCCAGCGTAGTCCAAGTCAGACTATTTCACAAAG
TCAGAGCGATAGGAAAGCACCCTGCCCTTCATCTTCATGTTCTCCCAAATGGAACTTAGGATCTTTTAACATAGGTGGTTCTGTGATAAC
ATCAGTGTTTTCCAAATCAAAGGAACGCTTTAAAAAATAGGACCTATTTTTTAAGACTTTACAGCCTTTGAAATGGTTTCCACGTGATTG
TTACGCCAGCAGTTCTCGTTTTGTTTGTTTTTCAATCTCAGTGAAATGGCTCTTTGCTTTCGAGTTCTCACGCAACGTACTGGGCAAATG
ACAATCCTCAGCCGCTGGTATTTTCTAAGGGGTCTCTTCACTTTGATGAGTGACATGAACACCGTGTCTCCTTCTCTTGTGTGTACCTAA
AGCCATATTTCCAAGTCTGTGGTACTCCAGGATTCCAGGAGTAAGCCTGTAGAAGAGATTTATTTTAAAAGAGATTGCTCTGAAATTTAT
CTTAAAAGAGCTTGCTCTGTCTACCTTGACAGAAATTGGAGTTTTAAAATTATGTGTTAATATTTTTATTTGCAGATTTCGTTTCCGTCA
ACTTAAACATTGTTGCCCTTCAACAAGGCTCTTGAATTAATAAAATTATAGTCTCTAAGAATTCCACATTTTATGGAAAGTTAGAGCAAA
ATCATTTTGAGTTAAGCCAGTTCTTAGCCTAATGCAAACTGCAGCGCCTTTAAGCATAAAGTAACACAACAGCATTGCACGGGGCCGGCA
CTGCCGCTGCCTTCACTGAAGGCTGCAGTGCTGTTCTGAGAGCTTGGAGGAGGCACCAGCGAGGATGACGTTTAGTGGAGCTCTTTCTGT
TGAAAAGAGCTCACGTTATCAACACCTTGTAAGGAAAATACAGTGTCTGAGTTTTCATCGGTCTTCACATGCTGCTATATATTCCACAGA
GTTCCTTGCATGTACTGAGCTTTTGTTTTAGATGGAATAGCACAAGGAGAAAAATCTTTAAACTTAGTGCTTTGTCTATTCTTTATTTCT
CTCAGGGTGGCCAGTATTTTGACTTATTTATCCTGCTTGAAAGCTACTTGAGATGTGTACTGCTATTCTAAACACGTGATCTAGTTTCTT
TCATCTCTGGCATAAGATTATATAACTTAATGTTAAGTGTCTTGAGGCATAAAAGACAAAATGTGGCTTATTTTAGGATCTGTTTTTTCA
TCGAGGTCTCGGGTATCCTTTCAAAGATAGTGAGAAGCAGACACTGCTCCTTGTGCAGCTCTGGTACCTCCTGCCCACTGCTGTCACTTC
AAGCCACTGGCAATGCTTCTGTCCTCGTGTCTTGGAGGAAAATCACCTGGGGGGAGGGGACTTCTTGTGGTAAGAGCAAGTGCAGGTATG
AAATGCGAAGATTGCCCCAGCTAAAAGTGGACAAGTCCGCTTTGTGAGATGAATACTTCCTGAGAAACTTGACAAGTATCTCTCCATTTT
ACCATTATGAAAACTATCATTAAAAAAAACAGTTTAGATGCCTTCTCCTTTTGAGGGAAAAAGGGTGCTTTTTATTGTATAAAGCAGCGT
CTTATGTATTTTGATATACCATTGTTTGAACTTCCGTCTTTAGCTGATAGATTCTCAAATATCCTTGATTTTGGATGTTCAGTATGTTTG
TGAGAGAGGTTTCTGGGAAGACTCTCTTTTTGCCCTCGGGAAAAAGCAAAATATCAATGTTTGGGTGACTGTGTAAAGCTCAGTGTGTAA
GAACATCTTTTTGTCTAGGTTTTCTTTCTGCTCTTTATTGAAGACAAACACTCACCAAAAAGAAAAATAAAAGTTTTCAGAGAAACTAAT
TTTCTTTGGCAAGAGTATTACTTAATATTTTGGCCTCCTAAAGTTTCCCTAGTTAGTACTCGGACTCCTGTGCTAATTGTCAGCTTACAT
ATCATTGTATAGAGACTGTTTATTCTGTACCAAACTGATTTCAAAAGTACTACATTGAAAATAAACCGGTGACTGTTTTTCTTCATAAAG
TTCTGCGTTTGGCATCTTCACTCTTTCCAAAATGTATCTGTACATCAGAAATGTCACTATTCCAAGTGTCTTTTTAGTGTGGCTTTAGTA
TGGCTTCCTTTTAATATTGTACATACATTGTATCTTTGTTTTATGGTAATAAGTAATAAAAATGTAGACTTCATATTTTGTACAAAATGT
CCTATGTACAGAATAAAAAAGTTCATAGAAACAGCAAATATAGGTAAGTGGCACAATTATTTTTCTTTAGAAAATATCTGTAACTTTATG
CATTAGTGAAATGTTAAGTACCGACATATTTTTTAACATTTTGTAATTCAAAACTTTTTGTTTTGACATTGTTTATGAAGAGAAACTTCA
TACACTTGCCATTTAATATGCTCTTTTATCTAATTTTCAAAAACTCTAAAAAACGGTGTATCATATGGACTAAATAAAGAACATGTGAAT

>73329_73329_2_RCOR1-PPP2R5C_RCOR1_chr14_103059662_ENST00000262241_PPP2R5C_chr14_102391478_ENST00000422945_length(amino acids)=228AA_BP=1
MRRTHVIAYGTGSKKALSVTDWYGTGSMYFLQNPEKNWRARPRRGAPEASGRPGRPAHRPCSELPRLSWCGGPEAARTCGVQEDGPSSDL
SVPGSKSGTTAWYWGPTLMPPPPCSSSLDEPELPSSQELLLLLPLGAAAAKLLFWPLLGAAAAEAAAAEAEEAAAPEAAVAAGEAQAAEA

--------------------------------------------------------------
>73329_73329_3_RCOR1-PPP2R5C_RCOR1_chr14_103059662_ENST00000570597_PPP2R5C_chr14_102391477_ENST00000422945_length(transcript)=3201nt_BP=352nt
ATGGTGGAGAAGGGCCCCGAGGTCTCAGGGAAGCGGAGAGGGAGGAACAACGCGGCCGCCTCCGCCTCCGCCGCCGCCGCCTCCGCCGCC
GCCTCGGCCGCCTGCGCCTCGCCAGCCGCCACTGCCGCCTCGGGCGCCGCCGCCTCCTCAGCCTCGGCCGCCGCCGCCTCAGCCGCCGCC
GCCCCCAATAATGGCCAGAATAAAAGTTTGGCGGCGGCGGCGCCCAATGGCAACAGCAGCAGCAACTCCTGGGAGGAAGGCAGCTCGGGC
TCGTCCAGCGACGAGGAGCACGGTGGCGGTGGCATGAGGGTCGGACCCCAGTACCAGGCGGTGGTGCCCGACTTCGACCCCGGCACAGAA
AGATCCGAAGAAGGACCGTCCTCTTGCACGCCGCAAGTCCGAGCTGCCTCAGGACCCCCACACCAAGAAAGCCTTGGAAGCTCACTGCAG
GGCCGATGAGCTGGCCTCCCAGGACGGCCGCTAGCCTCCGGGGCGCCGCGTCGGGGCCGGGCCCGCCAGTTCTTTTCCGGATTCTGTAGA
AAATACATACTTCCTGTGCCATACCAATCAGTTACACTCAAAGCTTTCTTGGACCCCGTTCCGTAGGCAATAACGTGCGTCCGCCTCAGC
GCGAGATTAGGAGTTCAAACAATGGTGACTTCCCAGAGCCCGCTGGCAGAGCCGCGGGTTGACGACGGTGTCCTCGCAGTGTCGCCGCCA
CCCCAGCGTAGTCCAAGTCAGACTATTTCACAAAGTCAGAGCGATAGGAAAGCACCCTGCCCTTCATCTTCATGTTCTCCCAAATGGAAC
TTAGGATCTTTTAACATAGGTGGTTCTGTGATAACATCAGTGTTTTCCAAATCAAAGGAACGCTTTAAAAAATAGGACCTATTTTTTAAG
ACTTTACAGCCTTTGAAATGGTTTCCACGTGATTGTTACGCCAGCAGTTCTCGTTTTGTTTGTTTTTCAATCTCAGTGAAATGGCTCTTT
GCTTTCGAGTTCTCACGCAACGTACTGGGCAAATGACAATCCTCAGCCGCTGGTATTTTCTAAGGGGTCTCTTCACTTTGATGAGTGACA
TGAACACCGTGTCTCCTTCTCTTGTGTGTACCTAAAGCCATATTTCCAAGTCTGTGGTACTCCAGGATTCCAGGAGTAAGCCTGTAGAAG
AGATTTATTTTAAAAGAGATTGCTCTGAAATTTATCTTAAAAGAGCTTGCTCTGTCTACCTTGACAGAAATTGGAGTTTTAAAATTATGT
GTTAATATTTTTATTTGCAGATTTCGTTTCCGTCAACTTAAACATTGTTGCCCTTCAACAAGGCTCTTGAATTAATAAAATTATAGTCTC
TAAGAATTCCACATTTTATGGAAAGTTAGAGCAAAATCATTTTGAGTTAAGCCAGTTCTTAGCCTAATGCAAACTGCAGCGCCTTTAAGC
ATAAAGTAACACAACAGCATTGCACGGGGCCGGCACTGCCGCTGCCTTCACTGAAGGCTGCAGTGCTGTTCTGAGAGCTTGGAGGAGGCA
CCAGCGAGGATGACGTTTAGTGGAGCTCTTTCTGTTGAAAAGAGCTCACGTTATCAACACCTTGTAAGGAAAATACAGTGTCTGAGTTTT
CATCGGTCTTCACATGCTGCTATATATTCCACAGAGTTCCTTGCATGTACTGAGCTTTTGTTTTAGATGGAATAGCACAAGGAGAAAAAT
CTTTAAACTTAGTGCTTTGTCTATTCTTTATTTCTCTCAGGGTGGCCAGTATTTTGACTTATTTATCCTGCTTGAAAGCTACTTGAGATG
TGTACTGCTATTCTAAACACGTGATCTAGTTTCTTTCATCTCTGGCATAAGATTATATAACTTAATGTTAAGTGTCTTGAGGCATAAAAG
ACAAAATGTGGCTTATTTTAGGATCTGTTTTTTCATCGAGGTCTCGGGTATCCTTTCAAAGATAGTGAGAAGCAGACACTGCTCCTTGTG
CAGCTCTGGTACCTCCTGCCCACTGCTGTCACTTCAAGCCACTGGCAATGCTTCTGTCCTCGTGTCTTGGAGGAAAATCACCTGGGGGGA
GGGGACTTCTTGTGGTAAGAGCAAGTGCAGGTATGAAATGCGAAGATTGCCCCAGCTAAAAGTGGACAAGTCCGCTTTGTGAGATGAATA
CTTCCTGAGAAACTTGACAAGTATCTCTCCATTTTACCATTATGAAAACTATCATTAAAAAAAACAGTTTAGATGCCTTCTCCTTTTGAG
GGAAAAAGGGTGCTTTTTATTGTATAAAGCAGCGTCTTATGTATTTTGATATACCATTGTTTGAACTTCCGTCTTTAGCTGATAGATTCT
CAAATATCCTTGATTTTGGATGTTCAGTATGTTTGTGAGAGAGGTTTCTGGGAAGACTCTCTTTTTGCCCTCGGGAAAAAGCAAAATATC
AATGTTTGGGTGACTGTGTAAAGCTCAGTGTGTAAGAACATCTTTTTGTCTAGGTTTTCTTTCTGCTCTTTATTGAAGACAAACACTCAC
CAAAAAGAAAAATAAAAGTTTTCAGAGAAACTAATTTTCTTTGGCAAGAGTATTACTTAATATTTTGGCCTCCTAAAGTTTCCCTAGTTA
GTACTCGGACTCCTGTGCTAATTGTCAGCTTACATATCATTGTATAGAGACTGTTTATTCTGTACCAAACTGATTTCAAAAGTACTACAT
TGAAAATAAACCGGTGACTGTTTTTCTTCATAAAGTTCTGCGTTTGGCATCTTCACTCTTTCCAAAATGTATCTGTACATCAGAAATGTC
ACTATTCCAAGTGTCTTTTTAGTGTGGCTTTAGTATGGCTTCCTTTTAATATTGTACATACATTGTATCTTTGTTTTATGGTAATAAGTA
ATAAAAATGTAGACTTCATATTTTGTACAAAATGTCCTATGTACAGAATAAAAAAGTTCATAGAAACAGCAAATATAGGTAAGTGGCACA
ATTATTTTTCTTTAGAAAATATCTGTAACTTTATGCATTAGTGAAATGTTAAGTACCGACATATTTTTTAACATTTTGTAATTCAAAACT
TTTTGTTTTGACATTGTTTATGAAGAGAAACTTCATACACTTGCCATTTAATATGCTCTTTTATCTAATTTTCAAAAACTCTAAAAAACG

>73329_73329_3_RCOR1-PPP2R5C_RCOR1_chr14_103059662_ENST00000570597_PPP2R5C_chr14_102391477_ENST00000422945_length(amino acids)=209AA_BP=1
MRRTHVIAYGTGSKKALSVTDWYGTGSMYFLQNPEKNWRARPRRGAPEASGRPGRPAHRPCSELPRLSWCGGPEAARTCGVQEDGPSSDL
SVPGSKSGTTAWYWGPTLMPPPPCSSSLDEPELPSSQELLLLLPLGAAAAKLLFWPLLGAAAAEAAAAEAEEAAAPEAAVAAGEAQAAEA

--------------------------------------------------------------
>73329_73329_4_RCOR1-PPP2R5C_RCOR1_chr14_103059662_ENST00000570597_PPP2R5C_chr14_102391478_ENST00000422945_length(transcript)=3201nt_BP=352nt
ATGGTGGAGAAGGGCCCCGAGGTCTCAGGGAAGCGGAGAGGGAGGAACAACGCGGCCGCCTCCGCCTCCGCCGCCGCCGCCTCCGCCGCC
GCCTCGGCCGCCTGCGCCTCGCCAGCCGCCACTGCCGCCTCGGGCGCCGCCGCCTCCTCAGCCTCGGCCGCCGCCGCCTCAGCCGCCGCC
GCCCCCAATAATGGCCAGAATAAAAGTTTGGCGGCGGCGGCGCCCAATGGCAACAGCAGCAGCAACTCCTGGGAGGAAGGCAGCTCGGGC
TCGTCCAGCGACGAGGAGCACGGTGGCGGTGGCATGAGGGTCGGACCCCAGTACCAGGCGGTGGTGCCCGACTTCGACCCCGGCACAGAA
AGATCCGAAGAAGGACCGTCCTCTTGCACGCCGCAAGTCCGAGCTGCCTCAGGACCCCCACACCAAGAAAGCCTTGGAAGCTCACTGCAG
GGCCGATGAGCTGGCCTCCCAGGACGGCCGCTAGCCTCCGGGGCGCCGCGTCGGGGCCGGGCCCGCCAGTTCTTTTCCGGATTCTGTAGA
AAATACATACTTCCTGTGCCATACCAATCAGTTACACTCAAAGCTTTCTTGGACCCCGTTCCGTAGGCAATAACGTGCGTCCGCCTCAGC
GCGAGATTAGGAGTTCAAACAATGGTGACTTCCCAGAGCCCGCTGGCAGAGCCGCGGGTTGACGACGGTGTCCTCGCAGTGTCGCCGCCA
CCCCAGCGTAGTCCAAGTCAGACTATTTCACAAAGTCAGAGCGATAGGAAAGCACCCTGCCCTTCATCTTCATGTTCTCCCAAATGGAAC
TTAGGATCTTTTAACATAGGTGGTTCTGTGATAACATCAGTGTTTTCCAAATCAAAGGAACGCTTTAAAAAATAGGACCTATTTTTTAAG
ACTTTACAGCCTTTGAAATGGTTTCCACGTGATTGTTACGCCAGCAGTTCTCGTTTTGTTTGTTTTTCAATCTCAGTGAAATGGCTCTTT
GCTTTCGAGTTCTCACGCAACGTACTGGGCAAATGACAATCCTCAGCCGCTGGTATTTTCTAAGGGGTCTCTTCACTTTGATGAGTGACA
TGAACACCGTGTCTCCTTCTCTTGTGTGTACCTAAAGCCATATTTCCAAGTCTGTGGTACTCCAGGATTCCAGGAGTAAGCCTGTAGAAG
AGATTTATTTTAAAAGAGATTGCTCTGAAATTTATCTTAAAAGAGCTTGCTCTGTCTACCTTGACAGAAATTGGAGTTTTAAAATTATGT
GTTAATATTTTTATTTGCAGATTTCGTTTCCGTCAACTTAAACATTGTTGCCCTTCAACAAGGCTCTTGAATTAATAAAATTATAGTCTC
TAAGAATTCCACATTTTATGGAAAGTTAGAGCAAAATCATTTTGAGTTAAGCCAGTTCTTAGCCTAATGCAAACTGCAGCGCCTTTAAGC
ATAAAGTAACACAACAGCATTGCACGGGGCCGGCACTGCCGCTGCCTTCACTGAAGGCTGCAGTGCTGTTCTGAGAGCTTGGAGGAGGCA
CCAGCGAGGATGACGTTTAGTGGAGCTCTTTCTGTTGAAAAGAGCTCACGTTATCAACACCTTGTAAGGAAAATACAGTGTCTGAGTTTT
CATCGGTCTTCACATGCTGCTATATATTCCACAGAGTTCCTTGCATGTACTGAGCTTTTGTTTTAGATGGAATAGCACAAGGAGAAAAAT
CTTTAAACTTAGTGCTTTGTCTATTCTTTATTTCTCTCAGGGTGGCCAGTATTTTGACTTATTTATCCTGCTTGAAAGCTACTTGAGATG
TGTACTGCTATTCTAAACACGTGATCTAGTTTCTTTCATCTCTGGCATAAGATTATATAACTTAATGTTAAGTGTCTTGAGGCATAAAAG
ACAAAATGTGGCTTATTTTAGGATCTGTTTTTTCATCGAGGTCTCGGGTATCCTTTCAAAGATAGTGAGAAGCAGACACTGCTCCTTGTG
CAGCTCTGGTACCTCCTGCCCACTGCTGTCACTTCAAGCCACTGGCAATGCTTCTGTCCTCGTGTCTTGGAGGAAAATCACCTGGGGGGA
GGGGACTTCTTGTGGTAAGAGCAAGTGCAGGTATGAAATGCGAAGATTGCCCCAGCTAAAAGTGGACAAGTCCGCTTTGTGAGATGAATA
CTTCCTGAGAAACTTGACAAGTATCTCTCCATTTTACCATTATGAAAACTATCATTAAAAAAAACAGTTTAGATGCCTTCTCCTTTTGAG
GGAAAAAGGGTGCTTTTTATTGTATAAAGCAGCGTCTTATGTATTTTGATATACCATTGTTTGAACTTCCGTCTTTAGCTGATAGATTCT
CAAATATCCTTGATTTTGGATGTTCAGTATGTTTGTGAGAGAGGTTTCTGGGAAGACTCTCTTTTTGCCCTCGGGAAAAAGCAAAATATC
AATGTTTGGGTGACTGTGTAAAGCTCAGTGTGTAAGAACATCTTTTTGTCTAGGTTTTCTTTCTGCTCTTTATTGAAGACAAACACTCAC
CAAAAAGAAAAATAAAAGTTTTCAGAGAAACTAATTTTCTTTGGCAAGAGTATTACTTAATATTTTGGCCTCCTAAAGTTTCCCTAGTTA
GTACTCGGACTCCTGTGCTAATTGTCAGCTTACATATCATTGTATAGAGACTGTTTATTCTGTACCAAACTGATTTCAAAAGTACTACAT
TGAAAATAAACCGGTGACTGTTTTTCTTCATAAAGTTCTGCGTTTGGCATCTTCACTCTTTCCAAAATGTATCTGTACATCAGAAATGTC
ACTATTCCAAGTGTCTTTTTAGTGTGGCTTTAGTATGGCTTCCTTTTAATATTGTACATACATTGTATCTTTGTTTTATGGTAATAAGTA
ATAAAAATGTAGACTTCATATTTTGTACAAAATGTCCTATGTACAGAATAAAAAAGTTCATAGAAACAGCAAATATAGGTAAGTGGCACA
ATTATTTTTCTTTAGAAAATATCTGTAACTTTATGCATTAGTGAAATGTTAAGTACCGACATATTTTTTAACATTTTGTAATTCAAAACT
TTTTGTTTTGACATTGTTTATGAAGAGAAACTTCATACACTTGCCATTTAATATGCTCTTTTATCTAATTTTCAAAAACTCTAAAAAACG

>73329_73329_4_RCOR1-PPP2R5C_RCOR1_chr14_103059662_ENST00000570597_PPP2R5C_chr14_102391478_ENST00000422945_length(amino acids)=209AA_BP=1
MRRTHVIAYGTGSKKALSVTDWYGTGSMYFLQNPEKNWRARPRRGAPEASGRPGRPAHRPCSELPRLSWCGGPEAARTCGVQEDGPSSDL
SVPGSKSGTTAWYWGPTLMPPPPCSSSLDEPELPSSQELLLLLPLGAAAAKLLFWPLLGAAAAEAAAAEAEEAAAPEAAVAAGEAQAAEA

--------------------------------------------------------------
>73329_73329_5_RCOR1-PPP2R5C_RCOR1_chr14_103148315_ENST00000262241_PPP2R5C_chr14_102323023_ENST00000422945_length(transcript)=4869nt_BP=671nt
GTGAGGGCGGCGATGAGAGCGAAAGTTGCGCTCGGCTCGTCGCTGGGGGCTTGAAGCGGCTCCGCGCTCTGCCCGTTTGGGCCTCCCCCG
ACTCGGACTCGCGCCCGTGGGCTCCCGCCGCGCCCGCCCGGCCCCGCGCCGGCCCCGCGCCCCCTCCCCCGTCTCGGCGCCCCCTCCTCA
GGAGCCGCGGGTCCCCGCCACTTTCGCACGGCCCCGGCCCCCGCCGATGCCGGCCATGGTGGAGAAGGGCCCCGAGGTCTCAGGGAAGCG
GAGAGGGAGGAACAACGCGGCCGCCTCCGCCTCCGCCGCCGCCGCCTCCGCCGCCGCCTCGGCCGCCTGCGCCTCGCCAGCCGCCACTGC
CGCCTCGGGCGCCGCCGCCTCCTCAGCCTCGGCCGCCGCCGCCTCAGCCGCCGCCGCCCCCAATAATGGCCAGAATAAAAGTTTGGCGGC
GGCGGCGCCCAATGGCAACAGCAGCAGCAACTCCTGGGAGGAAGGCAGCTCGGGCTCGTCCAGCGACGAGGAGCACGGTGGCGGTGGCAT
GAGGGTCGGACCCCAGTACCAGGCGGTGGTGCCCGACTTCGACCCCGCCAAACTGGCAAGACGCAGTCAAGAACGGGACAATCTTGGCAT
GTTGGTCTGGTCACCCAATCAAAATCTGTCAGAAGCAAAGTATGTTCCTCCTGCTGATCAAGAGAAGCTTTTTATCCAGAAGTTACGTCA
GTGTTGCGTCCTCTTTGACTTTGTTTCTGATCCACTAAGTGACCTAAAGTGGAAGGAAGTAAAACGAGCTGCTTTAAGTGAAATGGTAGA
ATATATCACCCATAATCGGAATGTGATCACAGAGCCTATTTACCCAGAAGTAGTCCATATGTTTGCAGTTAACATGTTTCGAACATTACC
ACCTTCCTCCAATCCTACGGGAGCGGAATTTGACCCGGAGGAAGATGAACCAACGTTAGAAGCAGCCTGGCCTCATCTACAGCTTGTTTA
TGAATTTTTCTTAAGATTTTTAGAGTCTCCAGATTTCCAACCTAATATAGCGAAGAAATATATTGATCAGAAGTTTGTATTGCAGCTTTT
AGAGCTCTTTGACAGTGAAGATCCTCGGGAGAGAGATTTTCTTAAAACCACCCTTCACAGAATCTATGGGAAATTCCTAGGCTTGAGAGC
TTACATCAGAAAACAGATAAATAATATATTTTATAGGTTTATTTATGAAACAGAGCATCATAATGGCATAGCAGAGTTACTGGAAATATT
GGGAAGTATAATTAATGGATTTGCCTTACCACTAAAAGAAGAGCACAAGATTTTCTTATTGAAGGTGTTACTACCTTTGCACAAAGTGAA
ATCTCTGAGTGTCTACCATCCCCAGCTGGCATACTGTGTAGTGCAGTTTTTAGAAAAGGACAGCACCCTCACGGAACCAGTGGTGATGGC
ACTTCTCAAATACTGGCCAAAGACTCACAGTCCAAAAGAAGTAATGTTCTTAAACGAATTAGAAGAGATTTTAGATGTCATTGAACCATC
AGAATTTGTGAAGATCATGGAACCCCTCTTCCGGCAGTTGGCCAAATGTGTCTCCAGCCCACACTTCCAGGTGGCAGAGCGAGCTCTCTA
TTACTGGAATAATGAATACATCATGAGTTTAATCAGTGACAACGCAGCGAAGATTCTGCCCATCATGTTTCCTTCCTTGTACCGCAACTC
AAAGACCCATTGGAACAAGACAATACATGGCTTGATATACAACGCCCTGAAGCTCTTCATGGAGATGAACCAAAAGCTATTTGATGACTG
TACACAACAGTTCAAAGCAGAGAAACTAAAAGAGAAGCTAAAAATGAAAGAACGGGAAGAAGCATGGGTTAAAATAGAAAATCTAGCCAA
AGCCAATCCCCAGTACACAGTGTATAGTCAAGCCAGCACCATGAGCATTCCGGTTGCAATGGAGACAGATGGGCCTTTATTTGAAGATGT
GCAGATGCTGAGAAAGACAGTGAAGGACGAGGCTCATCAGGCACAGAAAGATCCGAAGAAGGACCGTCCTCTTGCACGCCGCAAGTCCGA
GCTGCCTCAGGACCCCCACACCAAGAAAGCCTTGGAAGCTCACTGCAGGGCCGATGAGCTGGCCTCCCAGGACGGCCGCTAGCCTCCGGG
GCGCCGCGTCGGGGCCGGGCCCGCCAGTTCTTTTCCGGATTCTGTAGAAAATACATACTTCCTGTGCCATACCAATCAGTTACACTCAAA
GCTTTCTTGGACCCCGTTCCGTAGGCAATAACGTGCGTCCGCCTCAGCGCGAGATTAGGAGTTCAAACAATGGTGACTTCCCAGAGCCCG
CTGGCAGAGCCGCGGGTTGACGACGGTGTCCTCGCAGTGTCGCCGCCACCCCAGCGTAGTCCAAGTCAGACTATTTCACAAAGTCAGAGC
GATAGGAAAGCACCCTGCCCTTCATCTTCATGTTCTCCCAAATGGAACTTAGGATCTTTTAACATAGGTGGTTCTGTGATAACATCAGTG
TTTTCCAAATCAAAGGAACGCTTTAAAAAATAGGACCTATTTTTTAAGACTTTACAGCCTTTGAAATGGTTTCCACGTGATTGTTACGCC
AGCAGTTCTCGTTTTGTTTGTTTTTCAATCTCAGTGAAATGGCTCTTTGCTTTCGAGTTCTCACGCAACGTACTGGGCAAATGACAATCC
TCAGCCGCTGGTATTTTCTAAGGGGTCTCTTCACTTTGATGAGTGACATGAACACCGTGTCTCCTTCTCTTGTGTGTACCTAAAGCCATA
TTTCCAAGTCTGTGGTACTCCAGGATTCCAGGAGTAAGCCTGTAGAAGAGATTTATTTTAAAAGAGATTGCTCTGAAATTTATCTTAAAA
GAGCTTGCTCTGTCTACCTTGACAGAAATTGGAGTTTTAAAATTATGTGTTAATATTTTTATTTGCAGATTTCGTTTCCGTCAACTTAAA
CATTGTTGCCCTTCAACAAGGCTCTTGAATTAATAAAATTATAGTCTCTAAGAATTCCACATTTTATGGAAAGTTAGAGCAAAATCATTT
TGAGTTAAGCCAGTTCTTAGCCTAATGCAAACTGCAGCGCCTTTAAGCATAAAGTAACACAACAGCATTGCACGGGGCCGGCACTGCCGC
TGCCTTCACTGAAGGCTGCAGTGCTGTTCTGAGAGCTTGGAGGAGGCACCAGCGAGGATGACGTTTAGTGGAGCTCTTTCTGTTGAAAAG
AGCTCACGTTATCAACACCTTGTAAGGAAAATACAGTGTCTGAGTTTTCATCGGTCTTCACATGCTGCTATATATTCCACAGAGTTCCTT
GCATGTACTGAGCTTTTGTTTTAGATGGAATAGCACAAGGAGAAAAATCTTTAAACTTAGTGCTTTGTCTATTCTTTATTTCTCTCAGGG
TGGCCAGTATTTTGACTTATTTATCCTGCTTGAAAGCTACTTGAGATGTGTACTGCTATTCTAAACACGTGATCTAGTTTCTTTCATCTC
TGGCATAAGATTATATAACTTAATGTTAAGTGTCTTGAGGCATAAAAGACAAAATGTGGCTTATTTTAGGATCTGTTTTTTCATCGAGGT
CTCGGGTATCCTTTCAAAGATAGTGAGAAGCAGACACTGCTCCTTGTGCAGCTCTGGTACCTCCTGCCCACTGCTGTCACTTCAAGCCAC
TGGCAATGCTTCTGTCCTCGTGTCTTGGAGGAAAATCACCTGGGGGGAGGGGACTTCTTGTGGTAAGAGCAAGTGCAGGTATGAAATGCG
AAGATTGCCCCAGCTAAAAGTGGACAAGTCCGCTTTGTGAGATGAATACTTCCTGAGAAACTTGACAAGTATCTCTCCATTTTACCATTA
TGAAAACTATCATTAAAAAAAACAGTTTAGATGCCTTCTCCTTTTGAGGGAAAAAGGGTGCTTTTTATTGTATAAAGCAGCGTCTTATGT
ATTTTGATATACCATTGTTTGAACTTCCGTCTTTAGCTGATAGATTCTCAAATATCCTTGATTTTGGATGTTCAGTATGTTTGTGAGAGA
GGTTTCTGGGAAGACTCTCTTTTTGCCCTCGGGAAAAAGCAAAATATCAATGTTTGGGTGACTGTGTAAAGCTCAGTGTGTAAGAACATC
TTTTTGTCTAGGTTTTCTTTCTGCTCTTTATTGAAGACAAACACTCACCAAAAAGAAAAATAAAAGTTTTCAGAGAAACTAATTTTCTTT
GGCAAGAGTATTACTTAATATTTTGGCCTCCTAAAGTTTCCCTAGTTAGTACTCGGACTCCTGTGCTAATTGTCAGCTTACATATCATTG
TATAGAGACTGTTTATTCTGTACCAAACTGATTTCAAAAGTACTACATTGAAAATAAACCGGTGACTGTTTTTCTTCATAAAGTTCTGCG
TTTGGCATCTTCACTCTTTCCAAAATGTATCTGTACATCAGAAATGTCACTATTCCAAGTGTCTTTTTAGTGTGGCTTTAGTATGGCTTC
CTTTTAATATTGTACATACATTGTATCTTTGTTTTATGGTAATAAGTAATAAAAATGTAGACTTCATATTTTGTACAAAATGTCCTATGT
ACAGAATAAAAAAGTTCATAGAAACAGCAAATATAGGTAAGTGGCACAATTATTTTTCTTTAGAAAATATCTGTAACTTTATGCATTAGT
GAAATGTTAAGTACCGACATATTTTTTAACATTTTGTAATTCAAAACTTTTTGTTTTGACATTGTTTATGAAGAGAAACTTCATACACTT
GCCATTTAATATGCTCTTTTATCTAATTTTCAAAAACTCTAAAAAACGGTGTATCATATGGACTAAATAAAGAACATGTGAATTTTATTG

>73329_73329_5_RCOR1-PPP2R5C_RCOR1_chr14_103148315_ENST00000262241_PPP2R5C_chr14_102323023_ENST00000422945_length(amino acids)=708AA_BP=19
MRSARRWGLEAAPRSARLGLPRLGLAPVGSRRARPAPRRPRAPSPVSAPPPQEPRVPATFARPRPPPMPAMVEKGPEVSGKRRGRNNAAA
SASAAAASAAASAACASPAATAASGAAASSASAAAASAAAAPNNGQNKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQA
VVPDFDPAKLARRSQERDNLGMLVWSPNQNLSEAKYVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNV
ITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDP
RERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQ
LAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIM
SLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVY

--------------------------------------------------------------
>73329_73329_6_RCOR1-PPP2R5C_RCOR1_chr14_103148315_ENST00000570597_PPP2R5C_chr14_102323023_ENST00000422945_length(transcript)=4634nt_BP=436nt
ATGGTGGAGAAGGGCCCCGAGGTCTCAGGGAAGCGGAGAGGGAGGAACAACGCGGCCGCCTCCGCCTCCGCCGCCGCCGCCTCCGCCGCC
GCCTCGGCCGCCTGCGCCTCGCCAGCCGCCACTGCCGCCTCGGGCGCCGCCGCCTCCTCAGCCTCGGCCGCCGCCGCCTCAGCCGCCGCC
GCCCCCAATAATGGCCAGAATAAAAGTTTGGCGGCGGCGGCGCCCAATGGCAACAGCAGCAGCAACTCCTGGGAGGAAGGCAGCTCGGGC
TCGTCCAGCGACGAGGAGCACGGTGGCGGTGGCATGAGGGTCGGACCCCAGTACCAGGCGGTGGTGCCCGACTTCGACCCCGCCAAACTG
GCAAGACGCAGTCAAGAACGGGACAATCTTGGCATGTTGGTCTGGTCACCCAATCAAAATCTGTCAGAAGCAAAGTATGTTCCTCCTGCT
GATCAAGAGAAGCTTTTTATCCAGAAGTTACGTCAGTGTTGCGTCCTCTTTGACTTTGTTTCTGATCCACTAAGTGACCTAAAGTGGAAG
GAAGTAAAACGAGCTGCTTTAAGTGAAATGGTAGAATATATCACCCATAATCGGAATGTGATCACAGAGCCTATTTACCCAGAAGTAGTC
CATATGTTTGCAGTTAACATGTTTCGAACATTACCACCTTCCTCCAATCCTACGGGAGCGGAATTTGACCCGGAGGAAGATGAACCAACG
TTAGAAGCAGCCTGGCCTCATCTACAGCTTGTTTATGAATTTTTCTTAAGATTTTTAGAGTCTCCAGATTTCCAACCTAATATAGCGAAG
AAATATATTGATCAGAAGTTTGTATTGCAGCTTTTAGAGCTCTTTGACAGTGAAGATCCTCGGGAGAGAGATTTTCTTAAAACCACCCTT
CACAGAATCTATGGGAAATTCCTAGGCTTGAGAGCTTACATCAGAAAACAGATAAATAATATATTTTATAGGTTTATTTATGAAACAGAG
CATCATAATGGCATAGCAGAGTTACTGGAAATATTGGGAAGTATAATTAATGGATTTGCCTTACCACTAAAAGAAGAGCACAAGATTTTC
TTATTGAAGGTGTTACTACCTTTGCACAAAGTGAAATCTCTGAGTGTCTACCATCCCCAGCTGGCATACTGTGTAGTGCAGTTTTTAGAA
AAGGACAGCACCCTCACGGAACCAGTGGTGATGGCACTTCTCAAATACTGGCCAAAGACTCACAGTCCAAAAGAAGTAATGTTCTTAAAC
GAATTAGAAGAGATTTTAGATGTCATTGAACCATCAGAATTTGTGAAGATCATGGAACCCCTCTTCCGGCAGTTGGCCAAATGTGTCTCC
AGCCCACACTTCCAGGTGGCAGAGCGAGCTCTCTATTACTGGAATAATGAATACATCATGAGTTTAATCAGTGACAACGCAGCGAAGATT
CTGCCCATCATGTTTCCTTCCTTGTACCGCAACTCAAAGACCCATTGGAACAAGACAATACATGGCTTGATATACAACGCCCTGAAGCTC
TTCATGGAGATGAACCAAAAGCTATTTGATGACTGTACACAACAGTTCAAAGCAGAGAAACTAAAAGAGAAGCTAAAAATGAAAGAACGG
GAAGAAGCATGGGTTAAAATAGAAAATCTAGCCAAAGCCAATCCCCAGTACACAGTGTATAGTCAAGCCAGCACCATGAGCATTCCGGTT
GCAATGGAGACAGATGGGCCTTTATTTGAAGATGTGCAGATGCTGAGAAAGACAGTGAAGGACGAGGCTCATCAGGCACAGAAAGATCCG
AAGAAGGACCGTCCTCTTGCACGCCGCAAGTCCGAGCTGCCTCAGGACCCCCACACCAAGAAAGCCTTGGAAGCTCACTGCAGGGCCGAT
GAGCTGGCCTCCCAGGACGGCCGCTAGCCTCCGGGGCGCCGCGTCGGGGCCGGGCCCGCCAGTTCTTTTCCGGATTCTGTAGAAAATACA
TACTTCCTGTGCCATACCAATCAGTTACACTCAAAGCTTTCTTGGACCCCGTTCCGTAGGCAATAACGTGCGTCCGCCTCAGCGCGAGAT
TAGGAGTTCAAACAATGGTGACTTCCCAGAGCCCGCTGGCAGAGCCGCGGGTTGACGACGGTGTCCTCGCAGTGTCGCCGCCACCCCAGC
GTAGTCCAAGTCAGACTATTTCACAAAGTCAGAGCGATAGGAAAGCACCCTGCCCTTCATCTTCATGTTCTCCCAAATGGAACTTAGGAT
CTTTTAACATAGGTGGTTCTGTGATAACATCAGTGTTTTCCAAATCAAAGGAACGCTTTAAAAAATAGGACCTATTTTTTAAGACTTTAC
AGCCTTTGAAATGGTTTCCACGTGATTGTTACGCCAGCAGTTCTCGTTTTGTTTGTTTTTCAATCTCAGTGAAATGGCTCTTTGCTTTCG
AGTTCTCACGCAACGTACTGGGCAAATGACAATCCTCAGCCGCTGGTATTTTCTAAGGGGTCTCTTCACTTTGATGAGTGACATGAACAC
CGTGTCTCCTTCTCTTGTGTGTACCTAAAGCCATATTTCCAAGTCTGTGGTACTCCAGGATTCCAGGAGTAAGCCTGTAGAAGAGATTTA
TTTTAAAAGAGATTGCTCTGAAATTTATCTTAAAAGAGCTTGCTCTGTCTACCTTGACAGAAATTGGAGTTTTAAAATTATGTGTTAATA
TTTTTATTTGCAGATTTCGTTTCCGTCAACTTAAACATTGTTGCCCTTCAACAAGGCTCTTGAATTAATAAAATTATAGTCTCTAAGAAT
TCCACATTTTATGGAAAGTTAGAGCAAAATCATTTTGAGTTAAGCCAGTTCTTAGCCTAATGCAAACTGCAGCGCCTTTAAGCATAAAGT
AACACAACAGCATTGCACGGGGCCGGCACTGCCGCTGCCTTCACTGAAGGCTGCAGTGCTGTTCTGAGAGCTTGGAGGAGGCACCAGCGA
GGATGACGTTTAGTGGAGCTCTTTCTGTTGAAAAGAGCTCACGTTATCAACACCTTGTAAGGAAAATACAGTGTCTGAGTTTTCATCGGT
CTTCACATGCTGCTATATATTCCACAGAGTTCCTTGCATGTACTGAGCTTTTGTTTTAGATGGAATAGCACAAGGAGAAAAATCTTTAAA
CTTAGTGCTTTGTCTATTCTTTATTTCTCTCAGGGTGGCCAGTATTTTGACTTATTTATCCTGCTTGAAAGCTACTTGAGATGTGTACTG
CTATTCTAAACACGTGATCTAGTTTCTTTCATCTCTGGCATAAGATTATATAACTTAATGTTAAGTGTCTTGAGGCATAAAAGACAAAAT
GTGGCTTATTTTAGGATCTGTTTTTTCATCGAGGTCTCGGGTATCCTTTCAAAGATAGTGAGAAGCAGACACTGCTCCTTGTGCAGCTCT
GGTACCTCCTGCCCACTGCTGTCACTTCAAGCCACTGGCAATGCTTCTGTCCTCGTGTCTTGGAGGAAAATCACCTGGGGGGAGGGGACT
TCTTGTGGTAAGAGCAAGTGCAGGTATGAAATGCGAAGATTGCCCCAGCTAAAAGTGGACAAGTCCGCTTTGTGAGATGAATACTTCCTG
AGAAACTTGACAAGTATCTCTCCATTTTACCATTATGAAAACTATCATTAAAAAAAACAGTTTAGATGCCTTCTCCTTTTGAGGGAAAAA
GGGTGCTTTTTATTGTATAAAGCAGCGTCTTATGTATTTTGATATACCATTGTTTGAACTTCCGTCTTTAGCTGATAGATTCTCAAATAT
CCTTGATTTTGGATGTTCAGTATGTTTGTGAGAGAGGTTTCTGGGAAGACTCTCTTTTTGCCCTCGGGAAAAAGCAAAATATCAATGTTT
GGGTGACTGTGTAAAGCTCAGTGTGTAAGAACATCTTTTTGTCTAGGTTTTCTTTCTGCTCTTTATTGAAGACAAACACTCACCAAAAAG
AAAAATAAAAGTTTTCAGAGAAACTAATTTTCTTTGGCAAGAGTATTACTTAATATTTTGGCCTCCTAAAGTTTCCCTAGTTAGTACTCG
GACTCCTGTGCTAATTGTCAGCTTACATATCATTGTATAGAGACTGTTTATTCTGTACCAAACTGATTTCAAAAGTACTACATTGAAAAT
AAACCGGTGACTGTTTTTCTTCATAAAGTTCTGCGTTTGGCATCTTCACTCTTTCCAAAATGTATCTGTACATCAGAAATGTCACTATTC
CAAGTGTCTTTTTAGTGTGGCTTTAGTATGGCTTCCTTTTAATATTGTACATACATTGTATCTTTGTTTTATGGTAATAAGTAATAAAAA
TGTAGACTTCATATTTTGTACAAAATGTCCTATGTACAGAATAAAAAAGTTCATAGAAACAGCAAATATAGGTAAGTGGCACAATTATTT
TTCTTTAGAAAATATCTGTAACTTTATGCATTAGTGAAATGTTAAGTACCGACATATTTTTTAACATTTTGTAATTCAAAACTTTTTGTT
TTGACATTGTTTATGAAGAGAAACTTCATACACTTGCCATTTAATATGCTCTTTTATCTAATTTTCAAAAACTCTAAAAAACGGTGTATC

>73329_73329_6_RCOR1-PPP2R5C_RCOR1_chr14_103148315_ENST00000570597_PPP2R5C_chr14_102323023_ENST00000422945_length(amino acids)=638AA_BP=146
MVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAASAAAAPNNGQNKSLAAAAPNGNSSSNSWEEGSSG
SSSDEEHGGGGMRVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLSEAKYVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWK
EVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAK
KYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIF
LLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVS
SPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKER
EEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRAD

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for RCOR1-PPP2R5C


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneRCOR1chr14:103059662chr14:102391477ENST00000570597+21278_257117.33333333333333483.0HDAC1
HgeneRCOR1chr14:103059662chr14:102391478ENST00000570597+21278_257117.33333333333333483.0HDAC1
HgeneRCOR1chr14:103148315chr14:102323023ENST00000570597+31278_257145.33333333333334483.0HDAC1
HgeneRCOR1chr14:103059662chr14:102391477ENST00000570597+212296_384117.33333333333333483.0KDM1A
HgeneRCOR1chr14:103059662chr14:102391478ENST00000570597+212296_384117.33333333333333483.0KDM1A
HgeneRCOR1chr14:103148315chr14:102323023ENST00000570597+312296_384145.33333333333334483.0KDM1A


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for RCOR1-PPP2R5C


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for RCOR1-PPP2R5C


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource