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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RECK-UNC13B (FusionGDB2 ID:73376)

Fusion Gene Summary for RECK-UNC13B

check button Fusion gene summary
Fusion gene informationFusion gene name: RECK-UNC13B
Fusion gene ID: 73376
HgeneTgene
Gene symbol

RECK

UNC13B

Gene ID

8434

10497

Gene namereversion inducing cysteine rich protein with kazal motifsunc-13 homolog B
SynonymsST15MUNC13|UNC13|Unc13h2|munc13-2
Cytomap

9p13.3

9p13.3

Type of geneprotein-codingprotein-coding
Descriptionreversion-inducing cysteine-rich protein with Kazal motifsmembrane-anchored glycoprotein (metastasis and invasion)suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein with kazal motifs)suppression of tumorigenicity 5 (reversion-inprotein unc-13 homolog Bhomolog of rat Munc13 (diacylglycerol-binding)unc-13-like
Modification date2020032220200329
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000479053, ENST00000377966, 
ENST00000378495, ENST00000378496, 
ENST00000396787, ENST00000481299, 
Fusion gene scores* DoF score9 X 7 X 6=37812 X 10 X 7=840
# samples 1013
** MAII scorelog2(10/378*10)=-1.91838623444635
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/840*10)=-2.69187770463767
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RECK [Title/Abstract] AND UNC13B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRECK(36058898)-UNC13B(35366943), # samples:1
RECK(36058898)-UNC13B(35366944), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRECK

GO:1904684

negative regulation of metalloendopeptidase activity

18194466

TgeneUNC13B

GO:0043065

positive regulation of apoptotic process

10233166

TgeneUNC13B

GO:0050714

positive regulation of protein secretion

19641095

TgeneUNC13B

GO:0060478

acrosomal vesicle exocytosis

22248876

TgeneUNC13B

GO:0071333

cellular response to glucose stimulus

19641095


check buttonFusion gene breakpoints across RECK (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across UNC13B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-12-0619-01ARECKchr9

36058898

+UNC13Bchr9

35366944

+
ChimerDB4GBMTCGA-12-0619RECKchr9

36058898

+UNC13Bchr9

35366943

+


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Fusion Gene ORF analysis for RECK-UNC13B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000479053ENST00000378495RECKchr9

36058898

+UNC13Bchr9

35366944

+
3UTR-3CDSENST00000479053ENST00000378495RECKchr9

36058898

+UNC13Bchr9

35366943

+
3UTR-3CDSENST00000479053ENST00000378496RECKchr9

36058898

+UNC13Bchr9

35366944

+
3UTR-3CDSENST00000479053ENST00000378496RECKchr9

36058898

+UNC13Bchr9

35366943

+
3UTR-3CDSENST00000479053ENST00000396787RECKchr9

36058898

+UNC13Bchr9

35366944

+
3UTR-3CDSENST00000479053ENST00000396787RECKchr9

36058898

+UNC13Bchr9

35366943

+
3UTR-intronENST00000479053ENST00000481299RECKchr9

36058898

+UNC13Bchr9

35366944

+
3UTR-intronENST00000479053ENST00000481299RECKchr9

36058898

+UNC13Bchr9

35366943

+
5CDS-intronENST00000377966ENST00000481299RECKchr9

36058898

+UNC13Bchr9

35366944

+
5CDS-intronENST00000377966ENST00000481299RECKchr9

36058898

+UNC13Bchr9

35366943

+
In-frameENST00000377966ENST00000378495RECKchr9

36058898

+UNC13Bchr9

35366944

+
In-frameENST00000377966ENST00000378495RECKchr9

36058898

+UNC13Bchr9

35366943

+
In-frameENST00000377966ENST00000378496RECKchr9

36058898

+UNC13Bchr9

35366944

+
In-frameENST00000377966ENST00000378496RECKchr9

36058898

+UNC13Bchr9

35366943

+
In-frameENST00000377966ENST00000396787RECKchr9

36058898

+UNC13Bchr9

35366944

+
In-frameENST00000377966ENST00000396787RECKchr9

36058898

+UNC13Bchr9

35366943

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000377966RECKchr936058898+ENST00000396787UNC13Bchr935366943+460880046444651333
ENST00000377966RECKchr936058898+ENST00000378495UNC13Bchr935366943+571480046444081314
ENST00000377966RECKchr936058898+ENST00000378496UNC13Bchr935366943+448780046444651333
ENST00000377966RECKchr936058898+ENST00000396787UNC13Bchr935366944+460880046444651333
ENST00000377966RECKchr936058898+ENST00000378495UNC13Bchr935366944+571480046444081314
ENST00000377966RECKchr936058898+ENST00000378496UNC13Bchr935366944+448780046444651333

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000377966ENST00000396787RECKchr936058898+UNC13Bchr935366943+0.0011469220.9988531
ENST00000377966ENST00000378495RECKchr936058898+UNC13Bchr935366943+0.0024362340.9975637
ENST00000377966ENST00000378496RECKchr936058898+UNC13Bchr935366943+0.0011874560.99881256
ENST00000377966ENST00000396787RECKchr936058898+UNC13Bchr935366944+0.0011469220.9988531
ENST00000377966ENST00000378495RECKchr936058898+UNC13Bchr935366944+0.0024362340.9975637
ENST00000377966ENST00000378496RECKchr936058898+UNC13Bchr935366944+0.0011874560.99881256

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Fusion Genomic Features for RECK-UNC13B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RECKchr936058898+UNC13Bchr935366943+1.39E-050.99998605
RECKchr936058898+UNC13Bchr935366943+1.39E-050.99998605
RECKchr936058898+UNC13Bchr935366943+1.39E-050.99998605
RECKchr936058898+UNC13Bchr935366943+1.39E-050.99998605

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for RECK-UNC13B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:36058898/chr9:35366943)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneUNC13Bchr9:36058898chr9:35366943ENST000003784959391172_12023891592.0Coiled coilOntology_term=ECO:0000255
TgeneUNC13Bchr9:36058898chr9:35366944ENST000003784959391172_12023891592.0Coiled coilOntology_term=ECO:0000255
TgeneUNC13Bchr9:36058898chr9:35366943ENST000003784959391013_11563891592.0DomainMHD1
TgeneUNC13Bchr9:36058898chr9:35366943ENST000003784959391263_14053891592.0DomainMHD2
TgeneUNC13Bchr9:36058898chr9:35366943ENST000003784959391419_15463891592.0DomainC2 3
TgeneUNC13Bchr9:36058898chr9:35366943ENST00000378495939583_7073891592.0DomainC2 2
TgeneUNC13Bchr9:36058898chr9:35366944ENST000003784959391013_11563891592.0DomainMHD1
TgeneUNC13Bchr9:36058898chr9:35366944ENST000003784959391263_14053891592.0DomainMHD2
TgeneUNC13Bchr9:36058898chr9:35366944ENST000003784959391419_15463891592.0DomainC2 3
TgeneUNC13Bchr9:36058898chr9:35366944ENST00000378495939583_7073891592.0DomainC2 2
TgeneUNC13Bchr9:36058898chr9:35366943ENST00000378495939477_5273891592.0Zinc fingerPhorbol-ester/DAG-type
TgeneUNC13Bchr9:36058898chr9:35366944ENST00000378495939477_5273891592.0Zinc fingerPhorbol-ester/DAG-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRECKchr9:36058898chr9:35366943ENST00000377966+321627_67378972.0DomainKazal-like 1
HgeneRECKchr9:36058898chr9:35366943ENST00000377966+321698_75278972.0DomainKazal-like 2
HgeneRECKchr9:36058898chr9:35366943ENST00000377966+321753_78978972.0DomainKazal-like 3
HgeneRECKchr9:36058898chr9:35366944ENST00000377966+321627_67378972.0DomainKazal-like 1
HgeneRECKchr9:36058898chr9:35366944ENST00000377966+321698_75278972.0DomainKazal-like 2
HgeneRECKchr9:36058898chr9:35366944ENST00000377966+321753_78978972.0DomainKazal-like 3
HgeneRECKchr9:36058898chr9:35366943ENST00000377966+32137_33878972.0RegionNote=5 X Knot repeats
HgeneRECKchr9:36058898chr9:35366944ENST00000377966+32137_33878972.0RegionNote=5 X Knot repeats
HgeneRECKchr9:36058898chr9:35366943ENST00000377966+321104_14178972.0RepeatNote=Knot 2
HgeneRECKchr9:36058898chr9:35366943ENST00000377966+321151_19778972.0RepeatNote=Knot 3
HgeneRECKchr9:36058898chr9:35366943ENST00000377966+321216_26378972.0RepeatNote=Knot 4
HgeneRECKchr9:36058898chr9:35366943ENST00000377966+321292_33878972.0RepeatNote=Knot 5
HgeneRECKchr9:36058898chr9:35366943ENST00000377966+32137_8478972.0RepeatNote=Knot 1
HgeneRECKchr9:36058898chr9:35366944ENST00000377966+321104_14178972.0RepeatNote=Knot 2
HgeneRECKchr9:36058898chr9:35366944ENST00000377966+321151_19778972.0RepeatNote=Knot 3
HgeneRECKchr9:36058898chr9:35366944ENST00000377966+321216_26378972.0RepeatNote=Knot 4
HgeneRECKchr9:36058898chr9:35366944ENST00000377966+321292_33878972.0RepeatNote=Knot 5
HgeneRECKchr9:36058898chr9:35366944ENST00000377966+32137_8478972.0RepeatNote=Knot 1


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Fusion Gene Sequence for RECK-UNC13B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>73376_73376_1_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366943_ENST00000378495_length(transcript)=5714nt_BP=800nt
GATGAACCCTTGTCAGGGGGCCGTGTCTGCGGGAGGCCGAAGGATCCCGGGTGACATGCTTTCTTTGGGTGCGAGGCAGCGTCTCGGCAG
AAAGAATATTGCGAGTATTACTGAGGGTACATGAAGGAGAGAAGCCCCTTTGGTTCGGCCTTGGACTAAGCCCTTGTTCTCAGGTGAACT
TGCAGTGTGATCTTGAGTAAGGTCAGTCTCCTCTCTCACCTCAGTGGCCCGAAACCTCAGGAGGTGGCAGAGGTTTTCTAATGACTCTCC
CAGCTCTGACATCCTCTGACTTCACTCTGGGAGAACGTGGGCTGGTGGACTCCTGGCAGAAGCCGACACACAGTTGGGCCATAACAAAGA
GCCCTGGTACGGGGCACGTTCCCGCCCCCGGGAGGTTTTGGAAACACTGTGAGGCAGGGGGCGGGGCTTGAGCGGGCCGCAGCCAGTCAC
CAAAGGGCCGGGCGCTGGGGGCGGGGCCTCGCGCGAGCGGCGGCGGTAGCGGCGGCAGCGGCTGCGGCCAAGCTGGGTCCGAGCATCCCG
CGGCTCTGGAGCCGCCCGGCCCGGACATGGCGACCGTCCGGGCCTCTCTGCGAGGTGCGCTGCTCCTTCTGCTGGCCGTGGCGGGGGTCG
CGGAGGTGGCAGGGGGCCTGGCTCCGGGCAGTGCGGGTGCATTGTGTTGTAATCATTCAAAGGATAACCAAATGTGCCGTGATGTATGTG
AACAGATTTTCTCCTCAAAAAGTGAATCCCGACTAAAACATCTGTTGCAGCGAGCCCCAGATTATTGCCCAGAGACAATGATTCCAGATG
ATGGTGACCCCTCTCTGCCTCAGTGGCTCCCGGAAGGGCCAGCCGGAGGGCTCTATGGCATTGACAGCATGCCAGATTTACGCAGAAAGA
AGCCACTGCCACTTGTCAGTGATCTGTCACTGGTCCAGTCTCGGAAGGCAGGAATCACTTCTGCAATGGCTACACGCACTTCTCTTAAGG
ACGAAGAGCTGAAATCCCACGTGTATAAGAAAACCCTGCAGGCCTTAATCTACCCCATTTCGTGCACCACTCCTCATAACTTTGAGGTCT
GGACGGCCACTACCCCAACCTACTGCTATGAGTGTGAAGGCCTGCTCTGGGGCATTGCCCGGCAGGGCATGCGCTGCAGCGAATGTGGAG
TCAAGTGCCATGAGAAGTGCCAGGATCTGCTCAATGCTGACTGCCTGCAGCGGGCTGCAGAAAAGAGCTGTAAACATGGAGCTGAGGACC
GGACCCAGAACATTATCATGGCCATGAAGGACCGCATGAAGATCCGAGAGCGAAATAAGCCAGAGATCTTTGAAGTTATCCGGGACGTCT
TCACAGTGAACAAAGCTGCCCATGTGCAGCAGATGAAAACAGTGAAGCAGAGTGTACTGGATGGCACCTCCAAATGGTCAGCCAAGATCA
CCATTACTGTGGTGTGTGCCCAGGGCCTACAAGCCAAGGACAAAACAGGATCCAGTGACCCTTACGTGACTGTGCAAGTCAGCAAAACTA
AGAAGCGTACCAAGACCATTTTTGGAAACTTGAATCCTGTTTGGGAGGAGAAGTTCCATTTTGAGTGCCACAACTCCTCTGACCGCATTA
AGGTGCGTGTATGGGATGAGGATGATGACATCAAGTCAAGAGTAAAGCAACGCCTAAAGCGAGAGTCTGATGATTTCCTTGGCCAAACCA
TCATTGAGGTTCGGACCCTAAGTGGCGAGATGGACGTCTGGTACAACTTGGAGAAGAGGACAGACAAATCAGCCGTCTCAGGGGCTATCC
GACTACAAATCAGTGTGGAGATCAAGGGGGAGGAGAAAGTAGCCCCATACCACGTGCAGTATACATGTCTCCATGAGAATCTTTTCCATT
ACCTCACAGACATTCAGGGCAGTGGAGGAGTCCGCATCCCTGAAGCTCGAGGAGACGATGCCTGGAAGGTGTACTTTGATGAGACAGCCC
AAGAAATTGTGGATGAATTTGCCATGCGTTATGGCATTGAGTCCATATATCAGGCCATGACGCACTTTGCATGTTTATCATCCAAGTACA
TGTGTCCTGGTGTGCCAGCAGTGATGAGCACCTTACTGGCCAACATCAACGCCTACTATGCCCACACAACTGCCTCTACCAATGTCTCTG
CATCTGATCGCTTTGCAGCCTCCAACTTTGGGAAAGAGAGATTTGTAAAACTGCTGGACCAGCTACACAACTCACTGAGGATCGACCTCT
CTACATACAGGAATAATTTCCCTGCTGGGAGTCCTGAACGGCTTCAGGACTTAAAATCCACAGTGGATTTGCTGACCAGCATTACTTTCT
TCAGAATGAAGGTACAAGAACTGCAAAGCCCTCCAAGAGCCAGCCAGGTGGTAAAGGATTGTGTGAAGGCCTGTTTGAACTCCACATATG
AATATATCTTCAACAACTGCCACGACTTATACAGCCGCCAGTACCAGCTGAAGCAGGAGCTACCTCCAGAGGAACAAGGGCCCAGCATTC
GGAACCTGGATTTCTGGCCCAAGCTCATCACACTCATCGTGTCAATCATAGAGGAAGATAAGAATTCCTACACACCTGTTCTGAACCAGT
TTCCTCAGGAGTTGAATGTGGGAAAAGTCAGCGCAGAAGTGATGTGGCATTTGTTTGCCCAAGACATGAAATATGCATTGGAGGAGCATG
AGAAAGACCACCTGTGTAAAAGTGCTGACTACATGAACCTGCACTTCAAGGTGAAGTGGCTCCACAATGAATACGTGCGGGATCTGCCTG
TCCTCCAGGGGCAGGTGCCTGAGTACCCAGCGTGGTTTGAGCAGTTCGTGCTACAATGGCTGGATGAGAATGAGGATGTATCCCTGGAAT
TCCTGCGTGGGGCCCTGGAACGAGATAAGAAGGATGGATTCCAGCAGACATCAGAGCATGCACTCTTTTCCTGCTCTGTGGTGGATGTCT
TCACACAACTCAATCAGAGCTTTGAGATCATCCGGAAGCTGGAATGCCCAGACCCCAGCATCCTTGCCCACTACATGAGGAGGTTTGCTA
AGACCATCGGGAAGGTGCTGATGCAGTATGCAGACATCTTGTCAAAGGACTTCCCAGCCTATTGCACAAAGGAGAAACTGCCCTGCATCC
TGATGAACAACGTGCAGCAACTGAGGGTCCAGCTGGAGAAAATGTTTGAGGCCATGGGAGGCAAGGAGCTGGACCTTGAAGCTGCAGACA
GTCTGAAGGAGCTGCAGGTGAAACTGAATACGGTTCTGGATGAGCTCAGCATGGTGTTTGGAAACAGTTTCCAGGTACGGATTGATGAGT
GTGTTCGACAAATGGCCGACATCCTGGGCCAGGTTCGGGGCACAGGGAATGCATCTCCAGACGCCAGGGCCTCAGCGGCTCAGGATGCAG
ATAGCGTACTCCGGCCTCTCATGGACTTCCTGGATGGCAACCTCACCCTCTTTGCCACTGTGTGTGAGAAGACGGTTCTGAAGCGTGTAC
TGAAGGAGCTCTGGCGCGTGGTGATGAACACAATGGAGAGGATGATTGTTCTGCCCCCACTCACTGACCAGACGGGCACCCAGCTGATCT
TCACTGCTGCCAAGGAGCTGAGCCATCTTTCCAAACTCAAGGATCACATGGTACGAGAGGAAACACGGAATCTCACTCCAAAGCAGTGTG
CAGTCCTTGACCTCGCCCTGGACACCATCAAGCAATACTTCCATGCAGGAGGCAATGGGCTGAAGAAAACCTTCCTGGAGAAGAGCCCAG
ATCTGCAGTCTCTACGCTATGCCCTGTCTCTGTACACACAGACTACTGACACTCTCATCAAGACCTTTGTGCGCTCGCAGACCACCCAAG
GGTCTGGTGTGGACGATCCTGTGGGAGAAGTCTCTATTCAGGTGGACTTGTTTACACACCCTGGTACTGGGGAGCACAAGGTCACAGTGA
AAGTGGTGGCTGCCAATGACCTCAAGTGGCAGACAGCGGGTATGTTCCGGCCTTTCGTGGAGGTGACTATGGTTGGCCCACACCAAAGTG
ATAAGAAGAGGAAGTTCACAACCAAATCCAAAAGCAACAACTGGGCCCCCAAGTACAATGAGACATTCCACTTCCTCCTGGGAAATGAGG
AGGGGCCCGAGTCCTATGAGTTGCAGATATGCGTGAAGGATTACTGCTTTGCCCGGGAAGATCGCGTGCTAGGGCTGGCTGTGATGCCTC
TGAGGGATGTCACAGCCAAGGGCAGCTGTGCCTGCTGGTGCCCCTTGGGCCGGAAGATCCATATGGATGAGACAGGCCTGACCATTCTCC
GGATTTTATCTCAGAGGAGCAATGACGAGGTGGCCCGAGAATTTGTGAAACTCAAATCAGAGTCTCGTTCCACGGAGGAGGGGAGCTGAA
CACCTTCGACTCCTGTGCCAATCAGGCAGCAGCAATTTCACAAATCAGGGCCAGTGGGAGTTAGCTGTGTAACCGGCTTAGGGTCTTTGC
AGTCAAGAGGCTGACCCCTTCAGTTAAAGATATTTAAGGAAAAATTTGGGGTGGTGATAATATGGCTTTTCACAGAAAGGGTCATGAAGC
CCTGGCCCAACAGGACTGTGGTACTAGGGGCTGGGATGTGGGGTTACCACATGGAGAGATTTTCCATTAAGAGAGAAGGACAAACATTTC
TGAGAGTGTCAGCCATTCTTGGTAGACACCTCTCCACTCCTCATCCCACCTCTACCCATCTCCATGCCACACCTTATCCAGTTAGACACA
TACATACCAATCATTAGAAGAACAAGTTTAGAAGGTGTGGAACTTGTGCCTGGCTGGCTGGGTAGTCAGCTGAGCCTGTTGCTGAGCCCG
GTGGTCTGGATTGGAGTATGGCCAGGGCAGGAGTACACAGAATAGAATTTAGACTGTCCCTTGAGTAGAATCCACTGATTTTCTGTGGCT
CCAGTGAGAACAAGGCTTTGAAACTGAACAAGATAACTTCTAGAAATGAACTGTACTAATCCCTTTCCCCAGATTGTATCATGAGTAGAA
TCAGGTTCACGTGGTGCTTCAAAGCCCTGAGAAGAATATTTCTTTGGACCCCAGGCACTAGGGGCCACCTGCCTGGGAGTCTCCCTGCCT
CACTCCTCTAGGCAGGGGAGTGATGCTTCAGGACGTGACAGGCTGTTCTAACATGTGTCTACCTGAGGGCTAGTTGAAGGATCCAGGAGT
ATTTTCTTCTTGGGTGGGCCCTGAACAAAGCCAAAAATTGTAGAAACCAGTCTAGAAAAAGTCCTGCTCATCTGTGGCCACTGCCTTCTA
GCCGTCCTCCACCTTGCAGAAAGAATCTAGCCTTTGGTCTCTCTCTCTCTCATCGGGGTCATTTGCTATTCCCCTCTGATATTCAACCCT
ATAGAAGGAGCCTGGACTCTGATCCCTCTGTACAGGCTGGATGGAAGGGGCCCTCCACACTTCCTGGGAGGTCAGAGACAAACTGTTTCA
GAGAGTCAGATGGACTTCCCAAGACTTGTTGAGAGATGTGACATGGTTCTTGGATTTCCTCTGTAGCAGCCTCCTGGACTTCCTGAGGAC
TCGACATTGTCCACAGATGTACTGGCCATTACATGAAACAAGAAACCAAGCATCTTTGCTGTTGTTAATTATTATATGTGCCATTGTTAC

>73376_73376_1_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366943_ENST00000378495_length(amino acids)=1314AA_BP=112
MGAGPRASGGGSGGSGCGQAGSEHPAALEPPGPDMATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFS
SKSESRLKHLLQRAPDYCPETMIPDDGDPSLPQWLPEGPAGGLYGIDSMPDLRRKKPLPLVSDLSLVQSRKAGITSAMATRTSLKDEELK
SHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSCKHGAEDRTQNI
IMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTK
TIFGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQIS
VEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGV
PAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKV
QELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQEL
NVGKVSAEVMWHLFAQDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWFEQFVLQWLDENEDVSLEFLRGA
LERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNV
QQLRVQLEKMFEAMGGKELDLEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDARASAAQDADSVLR
PLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTDQTGTQLIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVLDL
ALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQGSGVDDPVGEVSIQVDLFTHPGTGEHKVTVKVVAA
NDLKWQTAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYELQICVKDYCFAREDRVLGLAVMPLRDVT

--------------------------------------------------------------
>73376_73376_2_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366943_ENST00000378496_length(transcript)=4487nt_BP=800nt
GATGAACCCTTGTCAGGGGGCCGTGTCTGCGGGAGGCCGAAGGATCCCGGGTGACATGCTTTCTTTGGGTGCGAGGCAGCGTCTCGGCAG
AAAGAATATTGCGAGTATTACTGAGGGTACATGAAGGAGAGAAGCCCCTTTGGTTCGGCCTTGGACTAAGCCCTTGTTCTCAGGTGAACT
TGCAGTGTGATCTTGAGTAAGGTCAGTCTCCTCTCTCACCTCAGTGGCCCGAAACCTCAGGAGGTGGCAGAGGTTTTCTAATGACTCTCC
CAGCTCTGACATCCTCTGACTTCACTCTGGGAGAACGTGGGCTGGTGGACTCCTGGCAGAAGCCGACACACAGTTGGGCCATAACAAAGA
GCCCTGGTACGGGGCACGTTCCCGCCCCCGGGAGGTTTTGGAAACACTGTGAGGCAGGGGGCGGGGCTTGAGCGGGCCGCAGCCAGTCAC
CAAAGGGCCGGGCGCTGGGGGCGGGGCCTCGCGCGAGCGGCGGCGGTAGCGGCGGCAGCGGCTGCGGCCAAGCTGGGTCCGAGCATCCCG
CGGCTCTGGAGCCGCCCGGCCCGGACATGGCGACCGTCCGGGCCTCTCTGCGAGGTGCGCTGCTCCTTCTGCTGGCCGTGGCGGGGGTCG
CGGAGGTGGCAGGGGGCCTGGCTCCGGGCAGTGCGGGTGCATTGTGTTGTAATCATTCAAAGGATAACCAAATGTGCCGTGATGTATGTG
AACAGATTTTCTCCTCAAAAAGTGAATCCCGACTAAAACATCTGTTGCAGCGAGCCCCAGATTATTGCCCAGAGACAATGATTCCAGATG
ATGGTGACCCCTCTCTGCCTCAGTGGCTCCCGGAAGGGCCAGCCGGAGGGCTCTATGGCATTGACAGCATGCCAGATTTACGCAGAAAGA
AGCCACTGCCACTTGTCAGTGATCTGTCACTGGTCCAGTCTCGGAAGGCAGGAATCACTTCTGCAATGGCTACACGCACTTCTCTTAAGG
ACGAAGAGCTGAAATCCCACGTGTATAAGAAAACCCTGCAGGCCTTAATCTACCCCATTTCGTGCACCACTCCTCATAACTTTGAGGTCT
GGACGGCCACTACCCCAACCTACTGCTATGAGTGTGAAGGCCTGCTCTGGGGCATTGCCCGGCAGGGCATGCGCTGCAGCGAATGTGGAG
TCAAGTGCCATGAGAAGTGCCAGGATCTGCTCAATGCTGACTGCCTGCAGCGGGCTGCAGAAAAGAGCTGTAAACATGGAGCTGAGGACC
GGACCCAGAACATTATCATGGCCATGAAGGACCGCATGAAGATCCGAGAGCGAAATAAGCCAGAGATCTTTGAAGTTATCCGGGACGTCT
TCACAGTGAACAAAGCTGCCCATGTGCAGCAGATGAAAACAGTGAAGCAGAGTGTACTGGATGGCACCTCCAAATGGTCAGCCAAGATCA
CCATTACTGTGGTGTGTGCCCAGGGCCTACAAGCCAAGGACAAAACAGGATCCAGTGACCCTTACGTGACTGTGCAAGTCAGCAAAACTA
AGAAGCGTACCAAGACCATTTTTGGAAACTTGAATCCTGTTTGGGAGGAGAAGTTCCATTTTGAGTGCCACAACTCCTCTGACCGCATTA
AGGTGCGTGTATGGGATGAGGATGATGACATCAAGTCAAGAGTAAAGCAACGCCTAAAGCGAGAGTCTGATGATTTCCTTGGCCAAACCA
TCATTGAGGTTCGGACCCTAAGTGGCGAGATGGACGTCTGGTACAACTTGGAGAAGAGGACAGACAAATCAGCCGTCTCAGGGGCTATCC
GACTACAAATCAGTGTGGAGATCAAGGGGGAGGAGAAAGTAGCCCCATACCACGTGCAGTATACATGTCTCCATGAGAATCTTTTCCATT
ACCTCACAGACATTCAGGGCAGTGGAGGAGTCCGCATCCCTGAAGCTCGAGGAGACGATGCCTGGAAGGTGTACTTTGATGAGACAGCCC
AAGAAATTGTGGATGAATTTGCCATGCGTTATGGCATTGAGTCCATATATCAGGCCATGACGCACTTTGCATGTTTATCATCCAAGTACA
TGTGTCCTGGTGTGCCAGCAGTGATGAGCACCTTACTGGCCAACATCAACGCCTACTATGCCCACACAACTGCCTCTACCAATGTCTCTG
CATCTGATCGCTTTGCAGCCTCCAACTTTGGGAAAGAGAGATTTGTAAAACTGCTGGACCAGCTACACAACTCACTGAGGATCGACCTCT
CTACATACAGGAATAATTTCCCTGCTGGGAGTCCTGAACGGCTTCAGGACTTAAAATCCACAGTGGATTTGCTGACCAGCATTACTTTCT
TCAGAATGAAGGTACAAGAACTGCAAAGCCCTCCAAGAGCCAGCCAGGTGGTAAAGGATTGTGTGAAGGCCTGTTTGAACTCCACATATG
AATATATCTTCAACAACTGCCACGACTTATACAGCCGCCAGTACCAGCTGAAGCAGGAGCTACCTCCAGAGGAACAAGGGCCCAGCATTC
GGAACCTGGATTTCTGGCCCAAGCTCATCACACTCATCGTGTCAATCATAGAGGAAGATAAGAATTCCTACACACCTGTTCTGAACCAGT
TTCCTCAGGAGTTGAATGTGGGAAAAGTCAGCGCAGAAGTGATGTGGCATTTGTTTGCCCAAGACATGAAATATGCATTGGAGGAGCATG
AGAAAGACCACCTGTGTAAAAGTGCTGACTACATGAACCTGCACTTCAAGGTGAAGTGGCTCCACAATGAATACGTGCGGGATCTGCCTG
TCCTCCAGGGGCAGGTGCCTGAGTACCCAGCGTGGTTTGAGCAGTTCGTGCTACAATGGCTGGATGAGAATGAGGATGTATCCCTGGAAT
TCCTGCGTGGGGCCCTGGAACGAGATAAGAAGGATGGATTCCAGCAGACATCAGAGCATGCACTCTTTTCCTGCTCTGTGGTGGATGTCT
TCACACAACTCAATCAGAGCTTTGAGATCATCCGGAAGCTGGAATGCCCAGACCCCAGCATCCTTGCCCACTACATGAGGAGGTTTGCTA
AGACCATCGGGAAGGTGCTGATGCAGTATGCAGACATCTTGTCAAAGGACTTCCCAGCCTATTGCACAAAGGAGAAACTGCCCTGCATCC
TGATGAACAACGTGCAGCAACTGAGGGTCCAGCTGGAGAAAATGTTTGAGGCCATGGGAGGCAAGGAGCTGGACCTTGAAGCTGCAGACA
GTCTGAAGGAGCTGCAGGTGAAACTGAATACGGTTCTGGATGAGCTCAGCATGGTGTTTGGAAACAGTTTCCAGGTACGGATTGATGAGT
GTGTTCGACAAATGGCCGACATCCTGGGCCAGGTTCGGGGCACAGGGAATGCATCTCCAGACGCCAGGGCCTCAGCGGCTCAGGATGCAG
ATAGCGTACTCCGGCCTCTCATGGACTTCCTGGATGGCAACCTCACCCTCTTTGCCACTGTGTGTGAGAAGACGGTTCTGAAGCGTGTAC
TGAAGGAGCTCTGGCGCGTGGTGATGAACACAATGGAGAGGATGATTGTTCTGCCCCCACTCACTGACCAGACGGGCACCCAGCTGATCT
TCACTGCTGCCAAGGAGCTGAGCCATCTTTCCAAACTCAAGGATCACATGGTACGAGAGGAAACACGGAATCTCACTCCAAAGCAGTGTG
CAGTCCTTGACCTCGCCCTGGACACCATCAAGCAATACTTCCATGCAGGAGGCAATGGGCTGAAGAAAACCTTCCTGGAGAAGAGCCCAG
ATCTGCAGTCTCTACGCTATGCCCTGTCTCTGTACACACAGACTACTGACACTCTCATCAAGACCTTTGTGCGCTCGCAGACCACCCAAG
TGCATGATGGGAAAGGTATTAGATTTACTGCTAATGAGGACATTCGTCCGGAAAAGGGGTCTGGTGTGGACGATCCTGTGGGAGAAGTCT
CTATTCAGGTGGACTTGTTTACACACCCTGGTACTGGGGAGCACAAGGTCACAGTGAAAGTGGTGGCTGCCAATGACCTCAAGTGGCAGA
CAGCGGGTATGTTCCGGCCTTTCGTGGAGGTGACTATGGTTGGCCCACACCAAAGTGATAAGAAGAGGAAGTTCACAACCAAATCCAAAA
GCAACAACTGGGCCCCCAAGTACAATGAGACATTCCACTTCCTCCTGGGAAATGAGGAGGGGCCCGAGTCCTATGAGTTGCAGATATGCG
TGAAGGATTACTGCTTTGCCCGGGAAGATCGCGTGCTAGGGCTGGCTGTGATGCCTCTGAGGGATGTCACAGCCAAGGGCAGCTGTGCCT
GCTGGTGCCCCTTGGGCCGGAAGATCCATATGGATGAGACAGGCCTGACCATTCTCCGGATTTTATCTCAGAGGAGCAATGACGAGGTGG

>73376_73376_2_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366943_ENST00000378496_length(amino acids)=1333AA_BP=112
MGAGPRASGGGSGGSGCGQAGSEHPAALEPPGPDMATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFS
SKSESRLKHLLQRAPDYCPETMIPDDGDPSLPQWLPEGPAGGLYGIDSMPDLRRKKPLPLVSDLSLVQSRKAGITSAMATRTSLKDEELK
SHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSCKHGAEDRTQNI
IMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTK
TIFGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQIS
VEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGV
PAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKV
QELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQEL
NVGKVSAEVMWHLFAQDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWFEQFVLQWLDENEDVSLEFLRGA
LERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNV
QQLRVQLEKMFEAMGGKELDLEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDARASAAQDADSVLR
PLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTDQTGTQLIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVLDL
ALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQVHDGKGIRFTANEDIRPEKGSGVDDPVGEVSIQVD
LFTHPGTGEHKVTVKVVAANDLKWQTAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYELQICVKDYC

--------------------------------------------------------------
>73376_73376_3_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366943_ENST00000396787_length(transcript)=4608nt_BP=800nt
GATGAACCCTTGTCAGGGGGCCGTGTCTGCGGGAGGCCGAAGGATCCCGGGTGACATGCTTTCTTTGGGTGCGAGGCAGCGTCTCGGCAG
AAAGAATATTGCGAGTATTACTGAGGGTACATGAAGGAGAGAAGCCCCTTTGGTTCGGCCTTGGACTAAGCCCTTGTTCTCAGGTGAACT
TGCAGTGTGATCTTGAGTAAGGTCAGTCTCCTCTCTCACCTCAGTGGCCCGAAACCTCAGGAGGTGGCAGAGGTTTTCTAATGACTCTCC
CAGCTCTGACATCCTCTGACTTCACTCTGGGAGAACGTGGGCTGGTGGACTCCTGGCAGAAGCCGACACACAGTTGGGCCATAACAAAGA
GCCCTGGTACGGGGCACGTTCCCGCCCCCGGGAGGTTTTGGAAACACTGTGAGGCAGGGGGCGGGGCTTGAGCGGGCCGCAGCCAGTCAC
CAAAGGGCCGGGCGCTGGGGGCGGGGCCTCGCGCGAGCGGCGGCGGTAGCGGCGGCAGCGGCTGCGGCCAAGCTGGGTCCGAGCATCCCG
CGGCTCTGGAGCCGCCCGGCCCGGACATGGCGACCGTCCGGGCCTCTCTGCGAGGTGCGCTGCTCCTTCTGCTGGCCGTGGCGGGGGTCG
CGGAGGTGGCAGGGGGCCTGGCTCCGGGCAGTGCGGGTGCATTGTGTTGTAATCATTCAAAGGATAACCAAATGTGCCGTGATGTATGTG
AACAGATTTTCTCCTCAAAAAGTGAATCCCGACTAAAACATCTGTTGCAGCGAGCCCCAGATTATTGCCCAGAGACAATGATTCCAGATG
ATGGTGACCCCTCTCTGCCTCAGTGGCTCCCGGAAGGGCCAGCCGGAGGGCTCTATGGCATTGACAGCATGCCAGATTTACGCAGAAAGA
AGCCACTGCCACTTGTCAGTGATCTGTCACTGGTCCAGTCTCGGAAGGCAGGAATCACTTCTGCAATGGCTACACGCACTTCTCTTAAGG
ACGAAGAGCTGAAATCCCACGTGTATAAGAAAACCCTGCAGGCCTTAATCTACCCCATTTCGTGCACCACTCCTCATAACTTTGAGGTCT
GGACGGCCACTACCCCAACCTACTGCTATGAGTGTGAAGGCCTGCTCTGGGGCATTGCCCGGCAGGGCATGCGCTGCAGCGAATGTGGAG
TCAAGTGCCATGAGAAGTGCCAGGATCTGCTCAATGCTGACTGCCTGCAGCGGGCTGCAGAAAAGAGCTGTAAACATGGAGCTGAGGACC
GGACCCAGAACATTATCATGGCCATGAAGGACCGCATGAAGATCCGAGAGCGAAATAAGCCAGAGATCTTTGAAGTTATCCGGGACGTCT
TCACAGTGAACAAAGCTGCCCATGTGCAGCAGATGAAAACAGTGAAGCAGAGTGTACTGGATGGCACCTCCAAATGGTCAGCCAAGATCA
CCATTACTGTGGTGTGTGCCCAGGGCCTACAAGCCAAGGACAAAACAGGATCCAGTGACCCTTACGTGACTGTGCAAGTCAGCAAAACTA
AGAAGCGTACCAAGACCATTTTTGGAAACTTGAATCCTGTTTGGGAGGAGAAGTTCCATTTTGAGTGCCACAACTCCTCTGACCGCATTA
AGGTGCGTGTATGGGATGAGGATGATGACATCAAGTCAAGAGTAAAGCAACGCCTAAAGCGAGAGTCTGATGATTTCCTTGGCCAAACCA
TCATTGAGGTTCGGACCCTAAGTGGCGAGATGGACGTCTGGTACAACTTGGAGAAGAGGACAGACAAATCAGCCGTCTCAGGGGCTATCC
GACTACAAATCAGTGTGGAGATCAAGGGGGAGGAGAAAGTAGCCCCATACCACGTGCAGTATACATGTCTCCATGAGAATCTTTTCCATT
ACCTCACAGACATTCAGGGCAGTGGAGGAGTCCGCATCCCTGAAGCTCGAGGAGACGATGCCTGGAAGGTGTACTTTGATGAGACAGCCC
AAGAAATTGTGGATGAATTTGCCATGCGTTATGGCATTGAGTCCATATATCAGGCCATGACGCACTTTGCATGTTTATCATCCAAGTACA
TGTGTCCTGGTGTGCCAGCAGTGATGAGCACCTTACTGGCCAACATCAACGCCTACTATGCCCACACAACTGCCTCTACCAATGTCTCTG
CATCTGATCGCTTTGCAGCCTCCAACTTTGGGAAAGAGAGATTTGTAAAACTGCTGGACCAGCTACACAACTCACTGAGGATCGACCTCT
CTACATACAGGAATAATTTCCCTGCTGGGAGTCCTGAACGGCTTCAGGACTTAAAATCCACAGTGGATTTGCTGACCAGCATTACTTTCT
TCAGAATGAAGGTACAAGAACTGCAAAGCCCTCCAAGAGCCAGCCAGGTGGTAAAGGATTGTGTGAAGGCCTGTTTGAACTCCACATATG
AATATATCTTCAACAACTGCCACGACTTATACAGCCGCCAGTACCAGCTGAAGCAGGAGCTACCTCCAGAGGAACAAGGGCCCAGCATTC
GGAACCTGGATTTCTGGCCCAAGCTCATCACACTCATCGTGTCAATCATAGAGGAAGATAAGAATTCCTACACACCTGTTCTGAACCAGT
TTCCTCAGGAGTTGAATGTGGGAAAAGTCAGCGCAGAAGTGATGTGGCATTTGTTTGCCCAAGACATGAAATATGCATTGGAGGAGCATG
AGAAAGACCACCTGTGTAAAAGTGCTGACTACATGAACCTGCACTTCAAGGTGAAGTGGCTCCACAATGAATACGTGCGGGATCTGCCTG
TCCTCCAGGGGCAGGTGCCTGAGTACCCAGCGTGGTTTGAGCAGTTCGTGCTACAATGGCTGGATGAGAATGAGGATGTATCCCTGGAAT
TCCTGCGTGGGGCCCTGGAACGAGATAAGAAGGATGGATTCCAGCAGACATCAGAGCATGCACTCTTTTCCTGCTCTGTGGTGGATGTCT
TCACACAACTCAATCAGAGCTTTGAGATCATCCGGAAGCTGGAATGCCCAGACCCCAGCATCCTTGCCCACTACATGAGGAGGTTTGCTA
AGACCATCGGGAAGGTGCTGATGCAGTATGCAGACATCTTGTCAAAGGACTTCCCAGCCTATTGCACAAAGGAGAAACTGCCCTGCATCC
TGATGAACAACGTGCAGCAACTGAGGGTCCAGCTGGAGAAAATGTTTGAGGCCATGGGAGGCAAGGAGCTGGACCTTGAAGCTGCAGACA
GTCTGAAGGAGCTGCAGGTGAAACTGAATACGGTTCTGGATGAGCTCAGCATGGTGTTTGGAAACAGTTTCCAGGTACGGATTGATGAGT
GTGTTCGACAAATGGCCGACATCCTGGGCCAGGTTCGGGGCACAGGGAATGCATCTCCAGACGCCAGGGCCTCAGCGGCTCAGGATGCAG
ATAGCGTACTCCGGCCTCTCATGGACTTCCTGGATGGCAACCTCACCCTCTTTGCCACTGTGTGTGAGAAGACGGTTCTGAAGCGTGTAC
TGAAGGAGCTCTGGCGCGTGGTGATGAACACAATGGAGAGGATGATTGTTCTGCCCCCACTCACTGACCAGACGGGCACCCAGCTGATCT
TCACTGCTGCCAAGGAGCTGAGCCATCTTTCCAAACTCAAGGATCACATGGTACGAGAGGAAACACGGAATCTCACTCCAAAGCAGTGTG
CAGTCCTTGACCTCGCCCTGGACACCATCAAGCAATACTTCCATGCAGGAGGCAATGGGCTGAAGAAAACCTTCCTGGAGAAGAGCCCAG
ATCTGCAGTCTCTACGCTATGCCCTGTCTCTGTACACACAGACTACTGACACTCTCATCAAGACCTTTGTGCGCTCGCAGACCACCCAAG
TGCATGATGGGAAAGGTATTAGATTTACTGCTAATGAGGACATTCGTCCGGAAAAGGGGTCTGGTGTGGACGATCCTGTGGGAGAAGTCT
CTATTCAGGTGGACTTGTTTACACACCCTGGTACTGGGGAGCACAAGGTCACAGTGAAAGTGGTGGCTGCCAATGACCTCAAGTGGCAGA
CAGCGGGTATGTTCCGGCCTTTCGTGGAGGTGACTATGGTTGGCCCACACCAAAGTGATAAGAAGAGGAAGTTCACAACCAAATCCAAAA
GCAACAACTGGGCCCCCAAGTACAATGAGACATTCCACTTCCTCCTGGGAAATGAGGAGGGGCCCGAGTCCTATGAGTTGCAGATATGCG
TGAAGGATTACTGCTTTGCCCGGGAAGATCGCGTGCTAGGGCTGGCTGTGATGCCTCTGAGGGATGTCACAGCCAAGGGCAGCTGTGCCT
GCTGGTGCCCCTTGGGCCGGAAGATCCATATGGATGAGACAGGCCTGACCATTCTCCGGATTTTATCTCAGAGGAGCAATGACGAGGTGG
CCCGAGAATTTGTGAAACTCAAATCAGAGTCTCGTTCCACGGAGGAGGGGAGCTGAACACCTTCGACTCCTGTGCCAATCAGGCAGCAGC
AATTTCACAAATCAGGGCCAGTGGGAGTTAGCTGTGTAACCGGCTTAGGGTCTTTGCAGTCAAGAGGCTGACCCCTTCAGTTAAAGATAT

>73376_73376_3_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366943_ENST00000396787_length(amino acids)=1333AA_BP=112
MGAGPRASGGGSGGSGCGQAGSEHPAALEPPGPDMATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFS
SKSESRLKHLLQRAPDYCPETMIPDDGDPSLPQWLPEGPAGGLYGIDSMPDLRRKKPLPLVSDLSLVQSRKAGITSAMATRTSLKDEELK
SHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSCKHGAEDRTQNI
IMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTK
TIFGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQIS
VEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGV
PAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKV
QELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQEL
NVGKVSAEVMWHLFAQDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWFEQFVLQWLDENEDVSLEFLRGA
LERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNV
QQLRVQLEKMFEAMGGKELDLEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDARASAAQDADSVLR
PLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTDQTGTQLIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVLDL
ALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQVHDGKGIRFTANEDIRPEKGSGVDDPVGEVSIQVD
LFTHPGTGEHKVTVKVVAANDLKWQTAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYELQICVKDYC

--------------------------------------------------------------
>73376_73376_4_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366944_ENST00000378495_length(transcript)=5714nt_BP=800nt
GATGAACCCTTGTCAGGGGGCCGTGTCTGCGGGAGGCCGAAGGATCCCGGGTGACATGCTTTCTTTGGGTGCGAGGCAGCGTCTCGGCAG
AAAGAATATTGCGAGTATTACTGAGGGTACATGAAGGAGAGAAGCCCCTTTGGTTCGGCCTTGGACTAAGCCCTTGTTCTCAGGTGAACT
TGCAGTGTGATCTTGAGTAAGGTCAGTCTCCTCTCTCACCTCAGTGGCCCGAAACCTCAGGAGGTGGCAGAGGTTTTCTAATGACTCTCC
CAGCTCTGACATCCTCTGACTTCACTCTGGGAGAACGTGGGCTGGTGGACTCCTGGCAGAAGCCGACACACAGTTGGGCCATAACAAAGA
GCCCTGGTACGGGGCACGTTCCCGCCCCCGGGAGGTTTTGGAAACACTGTGAGGCAGGGGGCGGGGCTTGAGCGGGCCGCAGCCAGTCAC
CAAAGGGCCGGGCGCTGGGGGCGGGGCCTCGCGCGAGCGGCGGCGGTAGCGGCGGCAGCGGCTGCGGCCAAGCTGGGTCCGAGCATCCCG
CGGCTCTGGAGCCGCCCGGCCCGGACATGGCGACCGTCCGGGCCTCTCTGCGAGGTGCGCTGCTCCTTCTGCTGGCCGTGGCGGGGGTCG
CGGAGGTGGCAGGGGGCCTGGCTCCGGGCAGTGCGGGTGCATTGTGTTGTAATCATTCAAAGGATAACCAAATGTGCCGTGATGTATGTG
AACAGATTTTCTCCTCAAAAAGTGAATCCCGACTAAAACATCTGTTGCAGCGAGCCCCAGATTATTGCCCAGAGACAATGATTCCAGATG
ATGGTGACCCCTCTCTGCCTCAGTGGCTCCCGGAAGGGCCAGCCGGAGGGCTCTATGGCATTGACAGCATGCCAGATTTACGCAGAAAGA
AGCCACTGCCACTTGTCAGTGATCTGTCACTGGTCCAGTCTCGGAAGGCAGGAATCACTTCTGCAATGGCTACACGCACTTCTCTTAAGG
ACGAAGAGCTGAAATCCCACGTGTATAAGAAAACCCTGCAGGCCTTAATCTACCCCATTTCGTGCACCACTCCTCATAACTTTGAGGTCT
GGACGGCCACTACCCCAACCTACTGCTATGAGTGTGAAGGCCTGCTCTGGGGCATTGCCCGGCAGGGCATGCGCTGCAGCGAATGTGGAG
TCAAGTGCCATGAGAAGTGCCAGGATCTGCTCAATGCTGACTGCCTGCAGCGGGCTGCAGAAAAGAGCTGTAAACATGGAGCTGAGGACC
GGACCCAGAACATTATCATGGCCATGAAGGACCGCATGAAGATCCGAGAGCGAAATAAGCCAGAGATCTTTGAAGTTATCCGGGACGTCT
TCACAGTGAACAAAGCTGCCCATGTGCAGCAGATGAAAACAGTGAAGCAGAGTGTACTGGATGGCACCTCCAAATGGTCAGCCAAGATCA
CCATTACTGTGGTGTGTGCCCAGGGCCTACAAGCCAAGGACAAAACAGGATCCAGTGACCCTTACGTGACTGTGCAAGTCAGCAAAACTA
AGAAGCGTACCAAGACCATTTTTGGAAACTTGAATCCTGTTTGGGAGGAGAAGTTCCATTTTGAGTGCCACAACTCCTCTGACCGCATTA
AGGTGCGTGTATGGGATGAGGATGATGACATCAAGTCAAGAGTAAAGCAACGCCTAAAGCGAGAGTCTGATGATTTCCTTGGCCAAACCA
TCATTGAGGTTCGGACCCTAAGTGGCGAGATGGACGTCTGGTACAACTTGGAGAAGAGGACAGACAAATCAGCCGTCTCAGGGGCTATCC
GACTACAAATCAGTGTGGAGATCAAGGGGGAGGAGAAAGTAGCCCCATACCACGTGCAGTATACATGTCTCCATGAGAATCTTTTCCATT
ACCTCACAGACATTCAGGGCAGTGGAGGAGTCCGCATCCCTGAAGCTCGAGGAGACGATGCCTGGAAGGTGTACTTTGATGAGACAGCCC
AAGAAATTGTGGATGAATTTGCCATGCGTTATGGCATTGAGTCCATATATCAGGCCATGACGCACTTTGCATGTTTATCATCCAAGTACA
TGTGTCCTGGTGTGCCAGCAGTGATGAGCACCTTACTGGCCAACATCAACGCCTACTATGCCCACACAACTGCCTCTACCAATGTCTCTG
CATCTGATCGCTTTGCAGCCTCCAACTTTGGGAAAGAGAGATTTGTAAAACTGCTGGACCAGCTACACAACTCACTGAGGATCGACCTCT
CTACATACAGGAATAATTTCCCTGCTGGGAGTCCTGAACGGCTTCAGGACTTAAAATCCACAGTGGATTTGCTGACCAGCATTACTTTCT
TCAGAATGAAGGTACAAGAACTGCAAAGCCCTCCAAGAGCCAGCCAGGTGGTAAAGGATTGTGTGAAGGCCTGTTTGAACTCCACATATG
AATATATCTTCAACAACTGCCACGACTTATACAGCCGCCAGTACCAGCTGAAGCAGGAGCTACCTCCAGAGGAACAAGGGCCCAGCATTC
GGAACCTGGATTTCTGGCCCAAGCTCATCACACTCATCGTGTCAATCATAGAGGAAGATAAGAATTCCTACACACCTGTTCTGAACCAGT
TTCCTCAGGAGTTGAATGTGGGAAAAGTCAGCGCAGAAGTGATGTGGCATTTGTTTGCCCAAGACATGAAATATGCATTGGAGGAGCATG
AGAAAGACCACCTGTGTAAAAGTGCTGACTACATGAACCTGCACTTCAAGGTGAAGTGGCTCCACAATGAATACGTGCGGGATCTGCCTG
TCCTCCAGGGGCAGGTGCCTGAGTACCCAGCGTGGTTTGAGCAGTTCGTGCTACAATGGCTGGATGAGAATGAGGATGTATCCCTGGAAT
TCCTGCGTGGGGCCCTGGAACGAGATAAGAAGGATGGATTCCAGCAGACATCAGAGCATGCACTCTTTTCCTGCTCTGTGGTGGATGTCT
TCACACAACTCAATCAGAGCTTTGAGATCATCCGGAAGCTGGAATGCCCAGACCCCAGCATCCTTGCCCACTACATGAGGAGGTTTGCTA
AGACCATCGGGAAGGTGCTGATGCAGTATGCAGACATCTTGTCAAAGGACTTCCCAGCCTATTGCACAAAGGAGAAACTGCCCTGCATCC
TGATGAACAACGTGCAGCAACTGAGGGTCCAGCTGGAGAAAATGTTTGAGGCCATGGGAGGCAAGGAGCTGGACCTTGAAGCTGCAGACA
GTCTGAAGGAGCTGCAGGTGAAACTGAATACGGTTCTGGATGAGCTCAGCATGGTGTTTGGAAACAGTTTCCAGGTACGGATTGATGAGT
GTGTTCGACAAATGGCCGACATCCTGGGCCAGGTTCGGGGCACAGGGAATGCATCTCCAGACGCCAGGGCCTCAGCGGCTCAGGATGCAG
ATAGCGTACTCCGGCCTCTCATGGACTTCCTGGATGGCAACCTCACCCTCTTTGCCACTGTGTGTGAGAAGACGGTTCTGAAGCGTGTAC
TGAAGGAGCTCTGGCGCGTGGTGATGAACACAATGGAGAGGATGATTGTTCTGCCCCCACTCACTGACCAGACGGGCACCCAGCTGATCT
TCACTGCTGCCAAGGAGCTGAGCCATCTTTCCAAACTCAAGGATCACATGGTACGAGAGGAAACACGGAATCTCACTCCAAAGCAGTGTG
CAGTCCTTGACCTCGCCCTGGACACCATCAAGCAATACTTCCATGCAGGAGGCAATGGGCTGAAGAAAACCTTCCTGGAGAAGAGCCCAG
ATCTGCAGTCTCTACGCTATGCCCTGTCTCTGTACACACAGACTACTGACACTCTCATCAAGACCTTTGTGCGCTCGCAGACCACCCAAG
GGTCTGGTGTGGACGATCCTGTGGGAGAAGTCTCTATTCAGGTGGACTTGTTTACACACCCTGGTACTGGGGAGCACAAGGTCACAGTGA
AAGTGGTGGCTGCCAATGACCTCAAGTGGCAGACAGCGGGTATGTTCCGGCCTTTCGTGGAGGTGACTATGGTTGGCCCACACCAAAGTG
ATAAGAAGAGGAAGTTCACAACCAAATCCAAAAGCAACAACTGGGCCCCCAAGTACAATGAGACATTCCACTTCCTCCTGGGAAATGAGG
AGGGGCCCGAGTCCTATGAGTTGCAGATATGCGTGAAGGATTACTGCTTTGCCCGGGAAGATCGCGTGCTAGGGCTGGCTGTGATGCCTC
TGAGGGATGTCACAGCCAAGGGCAGCTGTGCCTGCTGGTGCCCCTTGGGCCGGAAGATCCATATGGATGAGACAGGCCTGACCATTCTCC
GGATTTTATCTCAGAGGAGCAATGACGAGGTGGCCCGAGAATTTGTGAAACTCAAATCAGAGTCTCGTTCCACGGAGGAGGGGAGCTGAA
CACCTTCGACTCCTGTGCCAATCAGGCAGCAGCAATTTCACAAATCAGGGCCAGTGGGAGTTAGCTGTGTAACCGGCTTAGGGTCTTTGC
AGTCAAGAGGCTGACCCCTTCAGTTAAAGATATTTAAGGAAAAATTTGGGGTGGTGATAATATGGCTTTTCACAGAAAGGGTCATGAAGC
CCTGGCCCAACAGGACTGTGGTACTAGGGGCTGGGATGTGGGGTTACCACATGGAGAGATTTTCCATTAAGAGAGAAGGACAAACATTTC
TGAGAGTGTCAGCCATTCTTGGTAGACACCTCTCCACTCCTCATCCCACCTCTACCCATCTCCATGCCACACCTTATCCAGTTAGACACA
TACATACCAATCATTAGAAGAACAAGTTTAGAAGGTGTGGAACTTGTGCCTGGCTGGCTGGGTAGTCAGCTGAGCCTGTTGCTGAGCCCG
GTGGTCTGGATTGGAGTATGGCCAGGGCAGGAGTACACAGAATAGAATTTAGACTGTCCCTTGAGTAGAATCCACTGATTTTCTGTGGCT
CCAGTGAGAACAAGGCTTTGAAACTGAACAAGATAACTTCTAGAAATGAACTGTACTAATCCCTTTCCCCAGATTGTATCATGAGTAGAA
TCAGGTTCACGTGGTGCTTCAAAGCCCTGAGAAGAATATTTCTTTGGACCCCAGGCACTAGGGGCCACCTGCCTGGGAGTCTCCCTGCCT
CACTCCTCTAGGCAGGGGAGTGATGCTTCAGGACGTGACAGGCTGTTCTAACATGTGTCTACCTGAGGGCTAGTTGAAGGATCCAGGAGT
ATTTTCTTCTTGGGTGGGCCCTGAACAAAGCCAAAAATTGTAGAAACCAGTCTAGAAAAAGTCCTGCTCATCTGTGGCCACTGCCTTCTA
GCCGTCCTCCACCTTGCAGAAAGAATCTAGCCTTTGGTCTCTCTCTCTCTCATCGGGGTCATTTGCTATTCCCCTCTGATATTCAACCCT
ATAGAAGGAGCCTGGACTCTGATCCCTCTGTACAGGCTGGATGGAAGGGGCCCTCCACACTTCCTGGGAGGTCAGAGACAAACTGTTTCA
GAGAGTCAGATGGACTTCCCAAGACTTGTTGAGAGATGTGACATGGTTCTTGGATTTCCTCTGTAGCAGCCTCCTGGACTTCCTGAGGAC
TCGACATTGTCCACAGATGTACTGGCCATTACATGAAACAAGAAACCAAGCATCTTTGCTGTTGTTAATTATTATATGTGCCATTGTTAC

>73376_73376_4_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366944_ENST00000378495_length(amino acids)=1314AA_BP=112
MGAGPRASGGGSGGSGCGQAGSEHPAALEPPGPDMATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFS
SKSESRLKHLLQRAPDYCPETMIPDDGDPSLPQWLPEGPAGGLYGIDSMPDLRRKKPLPLVSDLSLVQSRKAGITSAMATRTSLKDEELK
SHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSCKHGAEDRTQNI
IMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTK
TIFGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQIS
VEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGV
PAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKV
QELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQEL
NVGKVSAEVMWHLFAQDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWFEQFVLQWLDENEDVSLEFLRGA
LERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNV
QQLRVQLEKMFEAMGGKELDLEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDARASAAQDADSVLR
PLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTDQTGTQLIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVLDL
ALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQGSGVDDPVGEVSIQVDLFTHPGTGEHKVTVKVVAA
NDLKWQTAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYELQICVKDYCFAREDRVLGLAVMPLRDVT

--------------------------------------------------------------
>73376_73376_5_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366944_ENST00000378496_length(transcript)=4487nt_BP=800nt
GATGAACCCTTGTCAGGGGGCCGTGTCTGCGGGAGGCCGAAGGATCCCGGGTGACATGCTTTCTTTGGGTGCGAGGCAGCGTCTCGGCAG
AAAGAATATTGCGAGTATTACTGAGGGTACATGAAGGAGAGAAGCCCCTTTGGTTCGGCCTTGGACTAAGCCCTTGTTCTCAGGTGAACT
TGCAGTGTGATCTTGAGTAAGGTCAGTCTCCTCTCTCACCTCAGTGGCCCGAAACCTCAGGAGGTGGCAGAGGTTTTCTAATGACTCTCC
CAGCTCTGACATCCTCTGACTTCACTCTGGGAGAACGTGGGCTGGTGGACTCCTGGCAGAAGCCGACACACAGTTGGGCCATAACAAAGA
GCCCTGGTACGGGGCACGTTCCCGCCCCCGGGAGGTTTTGGAAACACTGTGAGGCAGGGGGCGGGGCTTGAGCGGGCCGCAGCCAGTCAC
CAAAGGGCCGGGCGCTGGGGGCGGGGCCTCGCGCGAGCGGCGGCGGTAGCGGCGGCAGCGGCTGCGGCCAAGCTGGGTCCGAGCATCCCG
CGGCTCTGGAGCCGCCCGGCCCGGACATGGCGACCGTCCGGGCCTCTCTGCGAGGTGCGCTGCTCCTTCTGCTGGCCGTGGCGGGGGTCG
CGGAGGTGGCAGGGGGCCTGGCTCCGGGCAGTGCGGGTGCATTGTGTTGTAATCATTCAAAGGATAACCAAATGTGCCGTGATGTATGTG
AACAGATTTTCTCCTCAAAAAGTGAATCCCGACTAAAACATCTGTTGCAGCGAGCCCCAGATTATTGCCCAGAGACAATGATTCCAGATG
ATGGTGACCCCTCTCTGCCTCAGTGGCTCCCGGAAGGGCCAGCCGGAGGGCTCTATGGCATTGACAGCATGCCAGATTTACGCAGAAAGA
AGCCACTGCCACTTGTCAGTGATCTGTCACTGGTCCAGTCTCGGAAGGCAGGAATCACTTCTGCAATGGCTACACGCACTTCTCTTAAGG
ACGAAGAGCTGAAATCCCACGTGTATAAGAAAACCCTGCAGGCCTTAATCTACCCCATTTCGTGCACCACTCCTCATAACTTTGAGGTCT
GGACGGCCACTACCCCAACCTACTGCTATGAGTGTGAAGGCCTGCTCTGGGGCATTGCCCGGCAGGGCATGCGCTGCAGCGAATGTGGAG
TCAAGTGCCATGAGAAGTGCCAGGATCTGCTCAATGCTGACTGCCTGCAGCGGGCTGCAGAAAAGAGCTGTAAACATGGAGCTGAGGACC
GGACCCAGAACATTATCATGGCCATGAAGGACCGCATGAAGATCCGAGAGCGAAATAAGCCAGAGATCTTTGAAGTTATCCGGGACGTCT
TCACAGTGAACAAAGCTGCCCATGTGCAGCAGATGAAAACAGTGAAGCAGAGTGTACTGGATGGCACCTCCAAATGGTCAGCCAAGATCA
CCATTACTGTGGTGTGTGCCCAGGGCCTACAAGCCAAGGACAAAACAGGATCCAGTGACCCTTACGTGACTGTGCAAGTCAGCAAAACTA
AGAAGCGTACCAAGACCATTTTTGGAAACTTGAATCCTGTTTGGGAGGAGAAGTTCCATTTTGAGTGCCACAACTCCTCTGACCGCATTA
AGGTGCGTGTATGGGATGAGGATGATGACATCAAGTCAAGAGTAAAGCAACGCCTAAAGCGAGAGTCTGATGATTTCCTTGGCCAAACCA
TCATTGAGGTTCGGACCCTAAGTGGCGAGATGGACGTCTGGTACAACTTGGAGAAGAGGACAGACAAATCAGCCGTCTCAGGGGCTATCC
GACTACAAATCAGTGTGGAGATCAAGGGGGAGGAGAAAGTAGCCCCATACCACGTGCAGTATACATGTCTCCATGAGAATCTTTTCCATT
ACCTCACAGACATTCAGGGCAGTGGAGGAGTCCGCATCCCTGAAGCTCGAGGAGACGATGCCTGGAAGGTGTACTTTGATGAGACAGCCC
AAGAAATTGTGGATGAATTTGCCATGCGTTATGGCATTGAGTCCATATATCAGGCCATGACGCACTTTGCATGTTTATCATCCAAGTACA
TGTGTCCTGGTGTGCCAGCAGTGATGAGCACCTTACTGGCCAACATCAACGCCTACTATGCCCACACAACTGCCTCTACCAATGTCTCTG
CATCTGATCGCTTTGCAGCCTCCAACTTTGGGAAAGAGAGATTTGTAAAACTGCTGGACCAGCTACACAACTCACTGAGGATCGACCTCT
CTACATACAGGAATAATTTCCCTGCTGGGAGTCCTGAACGGCTTCAGGACTTAAAATCCACAGTGGATTTGCTGACCAGCATTACTTTCT
TCAGAATGAAGGTACAAGAACTGCAAAGCCCTCCAAGAGCCAGCCAGGTGGTAAAGGATTGTGTGAAGGCCTGTTTGAACTCCACATATG
AATATATCTTCAACAACTGCCACGACTTATACAGCCGCCAGTACCAGCTGAAGCAGGAGCTACCTCCAGAGGAACAAGGGCCCAGCATTC
GGAACCTGGATTTCTGGCCCAAGCTCATCACACTCATCGTGTCAATCATAGAGGAAGATAAGAATTCCTACACACCTGTTCTGAACCAGT
TTCCTCAGGAGTTGAATGTGGGAAAAGTCAGCGCAGAAGTGATGTGGCATTTGTTTGCCCAAGACATGAAATATGCATTGGAGGAGCATG
AGAAAGACCACCTGTGTAAAAGTGCTGACTACATGAACCTGCACTTCAAGGTGAAGTGGCTCCACAATGAATACGTGCGGGATCTGCCTG
TCCTCCAGGGGCAGGTGCCTGAGTACCCAGCGTGGTTTGAGCAGTTCGTGCTACAATGGCTGGATGAGAATGAGGATGTATCCCTGGAAT
TCCTGCGTGGGGCCCTGGAACGAGATAAGAAGGATGGATTCCAGCAGACATCAGAGCATGCACTCTTTTCCTGCTCTGTGGTGGATGTCT
TCACACAACTCAATCAGAGCTTTGAGATCATCCGGAAGCTGGAATGCCCAGACCCCAGCATCCTTGCCCACTACATGAGGAGGTTTGCTA
AGACCATCGGGAAGGTGCTGATGCAGTATGCAGACATCTTGTCAAAGGACTTCCCAGCCTATTGCACAAAGGAGAAACTGCCCTGCATCC
TGATGAACAACGTGCAGCAACTGAGGGTCCAGCTGGAGAAAATGTTTGAGGCCATGGGAGGCAAGGAGCTGGACCTTGAAGCTGCAGACA
GTCTGAAGGAGCTGCAGGTGAAACTGAATACGGTTCTGGATGAGCTCAGCATGGTGTTTGGAAACAGTTTCCAGGTACGGATTGATGAGT
GTGTTCGACAAATGGCCGACATCCTGGGCCAGGTTCGGGGCACAGGGAATGCATCTCCAGACGCCAGGGCCTCAGCGGCTCAGGATGCAG
ATAGCGTACTCCGGCCTCTCATGGACTTCCTGGATGGCAACCTCACCCTCTTTGCCACTGTGTGTGAGAAGACGGTTCTGAAGCGTGTAC
TGAAGGAGCTCTGGCGCGTGGTGATGAACACAATGGAGAGGATGATTGTTCTGCCCCCACTCACTGACCAGACGGGCACCCAGCTGATCT
TCACTGCTGCCAAGGAGCTGAGCCATCTTTCCAAACTCAAGGATCACATGGTACGAGAGGAAACACGGAATCTCACTCCAAAGCAGTGTG
CAGTCCTTGACCTCGCCCTGGACACCATCAAGCAATACTTCCATGCAGGAGGCAATGGGCTGAAGAAAACCTTCCTGGAGAAGAGCCCAG
ATCTGCAGTCTCTACGCTATGCCCTGTCTCTGTACACACAGACTACTGACACTCTCATCAAGACCTTTGTGCGCTCGCAGACCACCCAAG
TGCATGATGGGAAAGGTATTAGATTTACTGCTAATGAGGACATTCGTCCGGAAAAGGGGTCTGGTGTGGACGATCCTGTGGGAGAAGTCT
CTATTCAGGTGGACTTGTTTACACACCCTGGTACTGGGGAGCACAAGGTCACAGTGAAAGTGGTGGCTGCCAATGACCTCAAGTGGCAGA
CAGCGGGTATGTTCCGGCCTTTCGTGGAGGTGACTATGGTTGGCCCACACCAAAGTGATAAGAAGAGGAAGTTCACAACCAAATCCAAAA
GCAACAACTGGGCCCCCAAGTACAATGAGACATTCCACTTCCTCCTGGGAAATGAGGAGGGGCCCGAGTCCTATGAGTTGCAGATATGCG
TGAAGGATTACTGCTTTGCCCGGGAAGATCGCGTGCTAGGGCTGGCTGTGATGCCTCTGAGGGATGTCACAGCCAAGGGCAGCTGTGCCT
GCTGGTGCCCCTTGGGCCGGAAGATCCATATGGATGAGACAGGCCTGACCATTCTCCGGATTTTATCTCAGAGGAGCAATGACGAGGTGG

>73376_73376_5_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366944_ENST00000378496_length(amino acids)=1333AA_BP=112
MGAGPRASGGGSGGSGCGQAGSEHPAALEPPGPDMATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFS
SKSESRLKHLLQRAPDYCPETMIPDDGDPSLPQWLPEGPAGGLYGIDSMPDLRRKKPLPLVSDLSLVQSRKAGITSAMATRTSLKDEELK
SHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSCKHGAEDRTQNI
IMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTK
TIFGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQIS
VEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGV
PAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKV
QELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQEL
NVGKVSAEVMWHLFAQDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWFEQFVLQWLDENEDVSLEFLRGA
LERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNV
QQLRVQLEKMFEAMGGKELDLEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDARASAAQDADSVLR
PLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTDQTGTQLIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVLDL
ALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQVHDGKGIRFTANEDIRPEKGSGVDDPVGEVSIQVD
LFTHPGTGEHKVTVKVVAANDLKWQTAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYELQICVKDYC

--------------------------------------------------------------
>73376_73376_6_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366944_ENST00000396787_length(transcript)=4608nt_BP=800nt
GATGAACCCTTGTCAGGGGGCCGTGTCTGCGGGAGGCCGAAGGATCCCGGGTGACATGCTTTCTTTGGGTGCGAGGCAGCGTCTCGGCAG
AAAGAATATTGCGAGTATTACTGAGGGTACATGAAGGAGAGAAGCCCCTTTGGTTCGGCCTTGGACTAAGCCCTTGTTCTCAGGTGAACT
TGCAGTGTGATCTTGAGTAAGGTCAGTCTCCTCTCTCACCTCAGTGGCCCGAAACCTCAGGAGGTGGCAGAGGTTTTCTAATGACTCTCC
CAGCTCTGACATCCTCTGACTTCACTCTGGGAGAACGTGGGCTGGTGGACTCCTGGCAGAAGCCGACACACAGTTGGGCCATAACAAAGA
GCCCTGGTACGGGGCACGTTCCCGCCCCCGGGAGGTTTTGGAAACACTGTGAGGCAGGGGGCGGGGCTTGAGCGGGCCGCAGCCAGTCAC
CAAAGGGCCGGGCGCTGGGGGCGGGGCCTCGCGCGAGCGGCGGCGGTAGCGGCGGCAGCGGCTGCGGCCAAGCTGGGTCCGAGCATCCCG
CGGCTCTGGAGCCGCCCGGCCCGGACATGGCGACCGTCCGGGCCTCTCTGCGAGGTGCGCTGCTCCTTCTGCTGGCCGTGGCGGGGGTCG
CGGAGGTGGCAGGGGGCCTGGCTCCGGGCAGTGCGGGTGCATTGTGTTGTAATCATTCAAAGGATAACCAAATGTGCCGTGATGTATGTG
AACAGATTTTCTCCTCAAAAAGTGAATCCCGACTAAAACATCTGTTGCAGCGAGCCCCAGATTATTGCCCAGAGACAATGATTCCAGATG
ATGGTGACCCCTCTCTGCCTCAGTGGCTCCCGGAAGGGCCAGCCGGAGGGCTCTATGGCATTGACAGCATGCCAGATTTACGCAGAAAGA
AGCCACTGCCACTTGTCAGTGATCTGTCACTGGTCCAGTCTCGGAAGGCAGGAATCACTTCTGCAATGGCTACACGCACTTCTCTTAAGG
ACGAAGAGCTGAAATCCCACGTGTATAAGAAAACCCTGCAGGCCTTAATCTACCCCATTTCGTGCACCACTCCTCATAACTTTGAGGTCT
GGACGGCCACTACCCCAACCTACTGCTATGAGTGTGAAGGCCTGCTCTGGGGCATTGCCCGGCAGGGCATGCGCTGCAGCGAATGTGGAG
TCAAGTGCCATGAGAAGTGCCAGGATCTGCTCAATGCTGACTGCCTGCAGCGGGCTGCAGAAAAGAGCTGTAAACATGGAGCTGAGGACC
GGACCCAGAACATTATCATGGCCATGAAGGACCGCATGAAGATCCGAGAGCGAAATAAGCCAGAGATCTTTGAAGTTATCCGGGACGTCT
TCACAGTGAACAAAGCTGCCCATGTGCAGCAGATGAAAACAGTGAAGCAGAGTGTACTGGATGGCACCTCCAAATGGTCAGCCAAGATCA
CCATTACTGTGGTGTGTGCCCAGGGCCTACAAGCCAAGGACAAAACAGGATCCAGTGACCCTTACGTGACTGTGCAAGTCAGCAAAACTA
AGAAGCGTACCAAGACCATTTTTGGAAACTTGAATCCTGTTTGGGAGGAGAAGTTCCATTTTGAGTGCCACAACTCCTCTGACCGCATTA
AGGTGCGTGTATGGGATGAGGATGATGACATCAAGTCAAGAGTAAAGCAACGCCTAAAGCGAGAGTCTGATGATTTCCTTGGCCAAACCA
TCATTGAGGTTCGGACCCTAAGTGGCGAGATGGACGTCTGGTACAACTTGGAGAAGAGGACAGACAAATCAGCCGTCTCAGGGGCTATCC
GACTACAAATCAGTGTGGAGATCAAGGGGGAGGAGAAAGTAGCCCCATACCACGTGCAGTATACATGTCTCCATGAGAATCTTTTCCATT
ACCTCACAGACATTCAGGGCAGTGGAGGAGTCCGCATCCCTGAAGCTCGAGGAGACGATGCCTGGAAGGTGTACTTTGATGAGACAGCCC
AAGAAATTGTGGATGAATTTGCCATGCGTTATGGCATTGAGTCCATATATCAGGCCATGACGCACTTTGCATGTTTATCATCCAAGTACA
TGTGTCCTGGTGTGCCAGCAGTGATGAGCACCTTACTGGCCAACATCAACGCCTACTATGCCCACACAACTGCCTCTACCAATGTCTCTG
CATCTGATCGCTTTGCAGCCTCCAACTTTGGGAAAGAGAGATTTGTAAAACTGCTGGACCAGCTACACAACTCACTGAGGATCGACCTCT
CTACATACAGGAATAATTTCCCTGCTGGGAGTCCTGAACGGCTTCAGGACTTAAAATCCACAGTGGATTTGCTGACCAGCATTACTTTCT
TCAGAATGAAGGTACAAGAACTGCAAAGCCCTCCAAGAGCCAGCCAGGTGGTAAAGGATTGTGTGAAGGCCTGTTTGAACTCCACATATG
AATATATCTTCAACAACTGCCACGACTTATACAGCCGCCAGTACCAGCTGAAGCAGGAGCTACCTCCAGAGGAACAAGGGCCCAGCATTC
GGAACCTGGATTTCTGGCCCAAGCTCATCACACTCATCGTGTCAATCATAGAGGAAGATAAGAATTCCTACACACCTGTTCTGAACCAGT
TTCCTCAGGAGTTGAATGTGGGAAAAGTCAGCGCAGAAGTGATGTGGCATTTGTTTGCCCAAGACATGAAATATGCATTGGAGGAGCATG
AGAAAGACCACCTGTGTAAAAGTGCTGACTACATGAACCTGCACTTCAAGGTGAAGTGGCTCCACAATGAATACGTGCGGGATCTGCCTG
TCCTCCAGGGGCAGGTGCCTGAGTACCCAGCGTGGTTTGAGCAGTTCGTGCTACAATGGCTGGATGAGAATGAGGATGTATCCCTGGAAT
TCCTGCGTGGGGCCCTGGAACGAGATAAGAAGGATGGATTCCAGCAGACATCAGAGCATGCACTCTTTTCCTGCTCTGTGGTGGATGTCT
TCACACAACTCAATCAGAGCTTTGAGATCATCCGGAAGCTGGAATGCCCAGACCCCAGCATCCTTGCCCACTACATGAGGAGGTTTGCTA
AGACCATCGGGAAGGTGCTGATGCAGTATGCAGACATCTTGTCAAAGGACTTCCCAGCCTATTGCACAAAGGAGAAACTGCCCTGCATCC
TGATGAACAACGTGCAGCAACTGAGGGTCCAGCTGGAGAAAATGTTTGAGGCCATGGGAGGCAAGGAGCTGGACCTTGAAGCTGCAGACA
GTCTGAAGGAGCTGCAGGTGAAACTGAATACGGTTCTGGATGAGCTCAGCATGGTGTTTGGAAACAGTTTCCAGGTACGGATTGATGAGT
GTGTTCGACAAATGGCCGACATCCTGGGCCAGGTTCGGGGCACAGGGAATGCATCTCCAGACGCCAGGGCCTCAGCGGCTCAGGATGCAG
ATAGCGTACTCCGGCCTCTCATGGACTTCCTGGATGGCAACCTCACCCTCTTTGCCACTGTGTGTGAGAAGACGGTTCTGAAGCGTGTAC
TGAAGGAGCTCTGGCGCGTGGTGATGAACACAATGGAGAGGATGATTGTTCTGCCCCCACTCACTGACCAGACGGGCACCCAGCTGATCT
TCACTGCTGCCAAGGAGCTGAGCCATCTTTCCAAACTCAAGGATCACATGGTACGAGAGGAAACACGGAATCTCACTCCAAAGCAGTGTG
CAGTCCTTGACCTCGCCCTGGACACCATCAAGCAATACTTCCATGCAGGAGGCAATGGGCTGAAGAAAACCTTCCTGGAGAAGAGCCCAG
ATCTGCAGTCTCTACGCTATGCCCTGTCTCTGTACACACAGACTACTGACACTCTCATCAAGACCTTTGTGCGCTCGCAGACCACCCAAG
TGCATGATGGGAAAGGTATTAGATTTACTGCTAATGAGGACATTCGTCCGGAAAAGGGGTCTGGTGTGGACGATCCTGTGGGAGAAGTCT
CTATTCAGGTGGACTTGTTTACACACCCTGGTACTGGGGAGCACAAGGTCACAGTGAAAGTGGTGGCTGCCAATGACCTCAAGTGGCAGA
CAGCGGGTATGTTCCGGCCTTTCGTGGAGGTGACTATGGTTGGCCCACACCAAAGTGATAAGAAGAGGAAGTTCACAACCAAATCCAAAA
GCAACAACTGGGCCCCCAAGTACAATGAGACATTCCACTTCCTCCTGGGAAATGAGGAGGGGCCCGAGTCCTATGAGTTGCAGATATGCG
TGAAGGATTACTGCTTTGCCCGGGAAGATCGCGTGCTAGGGCTGGCTGTGATGCCTCTGAGGGATGTCACAGCCAAGGGCAGCTGTGCCT
GCTGGTGCCCCTTGGGCCGGAAGATCCATATGGATGAGACAGGCCTGACCATTCTCCGGATTTTATCTCAGAGGAGCAATGACGAGGTGG
CCCGAGAATTTGTGAAACTCAAATCAGAGTCTCGTTCCACGGAGGAGGGGAGCTGAACACCTTCGACTCCTGTGCCAATCAGGCAGCAGC
AATTTCACAAATCAGGGCCAGTGGGAGTTAGCTGTGTAACCGGCTTAGGGTCTTTGCAGTCAAGAGGCTGACCCCTTCAGTTAAAGATAT

>73376_73376_6_RECK-UNC13B_RECK_chr9_36058898_ENST00000377966_UNC13B_chr9_35366944_ENST00000396787_length(amino acids)=1333AA_BP=112
MGAGPRASGGGSGGSGCGQAGSEHPAALEPPGPDMATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFS
SKSESRLKHLLQRAPDYCPETMIPDDGDPSLPQWLPEGPAGGLYGIDSMPDLRRKKPLPLVSDLSLVQSRKAGITSAMATRTSLKDEELK
SHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSCKHGAEDRTQNI
IMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTK
TIFGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQIS
VEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGV
PAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKV
QELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQEL
NVGKVSAEVMWHLFAQDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWFEQFVLQWLDENEDVSLEFLRGA
LERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNV
QQLRVQLEKMFEAMGGKELDLEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDARASAAQDADSVLR
PLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTDQTGTQLIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVLDL
ALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQVHDGKGIRFTANEDIRPEKGSGVDDPVGEVSIQVD
LFTHPGTGEHKVTVKVVAANDLKWQTAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYELQICVKDYC

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Fusion Gene PPI Analysis for RECK-UNC13B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RECK-UNC13B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RECK-UNC13B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource