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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RELN-ORC5 (FusionGDB2 ID:73451)

Fusion Gene Summary for RELN-ORC5

check button Fusion gene summary
Fusion gene informationFusion gene name: RELN-ORC5
Fusion gene ID: 73451
HgeneTgene
Gene symbol

RELN

ORC5

Gene ID

5649

5001

Gene namereelinorigin recognition complex subunit 5
SynonymsETL7|LIS2|PRO1598|RLORC5L|ORC5P|ORC5T|PPP1R117
Cytomap

7q22.1

7q22.1-q22.2

Type of geneprotein-codingprotein-coding
Descriptionreelinorigin recognition complex subunit 5protein phosphatase 1, regulatory subunit 117
Modification date2020032220200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000343529, ENST00000424685, 
ENST00000428762, ENST00000473945, 
ENST00000447452, ENST00000485726, 
ENST00000297431, ENST00000545943, 
Fusion gene scores* DoF score6 X 8 X 4=1927 X 6 X 7=294
# samples 811
** MAII scorelog2(8/192*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/294*10)=-1.4183126313117
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RELN [Title/Abstract] AND ORC5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRELN(103270387)-ORC5(103767340), # samples:3
Anticipated loss of major functional domain due to fusion event.RELN-ORC5 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
RELN-ORC5 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneORC5

GO:0006275

regulation of DNA replication

31160578


check buttonFusion gene breakpoints across RELN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ORC5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-CC-A8HV-01ARELNchr7

103175763

-ORC5chr7

103767340

-
ChimerDB4PRADTCGA-KK-A5A1-01ARELNchr7

103270387

-ORC5chr7

103767340

-
ChimerDB4PRADTCGA-KK-A5A1RELNchr7

103270387

-ORC5chr7

103767340

-


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Fusion Gene ORF analysis for RELN-ORC5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000343529ENST00000447452RELNchr7

103175763

-ORC5chr7

103767340

-
5CDS-intronENST00000343529ENST00000447452RELNchr7

103270387

-ORC5chr7

103767340

-
5CDS-intronENST00000343529ENST00000485726RELNchr7

103175763

-ORC5chr7

103767340

-
5CDS-intronENST00000343529ENST00000485726RELNchr7

103270387

-ORC5chr7

103767340

-
5CDS-intronENST00000424685ENST00000447452RELNchr7

103175763

-ORC5chr7

103767340

-
5CDS-intronENST00000424685ENST00000447452RELNchr7

103270387

-ORC5chr7

103767340

-
5CDS-intronENST00000424685ENST00000485726RELNchr7

103175763

-ORC5chr7

103767340

-
5CDS-intronENST00000424685ENST00000485726RELNchr7

103270387

-ORC5chr7

103767340

-
5CDS-intronENST00000428762ENST00000447452RELNchr7

103175763

-ORC5chr7

103767340

-
5CDS-intronENST00000428762ENST00000447452RELNchr7

103270387

-ORC5chr7

103767340

-
5CDS-intronENST00000428762ENST00000485726RELNchr7

103175763

-ORC5chr7

103767340

-
5CDS-intronENST00000428762ENST00000485726RELNchr7

103270387

-ORC5chr7

103767340

-
Frame-shiftENST00000343529ENST00000297431RELNchr7

103175763

-ORC5chr7

103767340

-
Frame-shiftENST00000343529ENST00000297431RELNchr7

103270387

-ORC5chr7

103767340

-
Frame-shiftENST00000424685ENST00000297431RELNchr7

103175763

-ORC5chr7

103767340

-
Frame-shiftENST00000424685ENST00000297431RELNchr7

103270387

-ORC5chr7

103767340

-
Frame-shiftENST00000428762ENST00000297431RELNchr7

103175763

-ORC5chr7

103767340

-
Frame-shiftENST00000428762ENST00000297431RELNchr7

103270387

-ORC5chr7

103767340

-
In-frameENST00000343529ENST00000545943RELNchr7

103175763

-ORC5chr7

103767340

-
In-frameENST00000343529ENST00000545943RELNchr7

103270387

-ORC5chr7

103767340

-
In-frameENST00000424685ENST00000545943RELNchr7

103175763

-ORC5chr7

103767340

-
In-frameENST00000424685ENST00000545943RELNchr7

103270387

-ORC5chr7

103767340

-
In-frameENST00000428762ENST00000545943RELNchr7

103175763

-ORC5chr7

103767340

-
In-frameENST00000428762ENST00000545943RELNchr7

103270387

-ORC5chr7

103767340

-
intron-3CDSENST00000473945ENST00000297431RELNchr7

103175763

-ORC5chr7

103767340

-
intron-3CDSENST00000473945ENST00000297431RELNchr7

103270387

-ORC5chr7

103767340

-
intron-3CDSENST00000473945ENST00000545943RELNchr7

103175763

-ORC5chr7

103767340

-
intron-3CDSENST00000473945ENST00000545943RELNchr7

103270387

-ORC5chr7

103767340

-
intron-intronENST00000473945ENST00000447452RELNchr7

103175763

-ORC5chr7

103767340

-
intron-intronENST00000473945ENST00000447452RELNchr7

103270387

-ORC5chr7

103767340

-
intron-intronENST00000473945ENST00000485726RELNchr7

103175763

-ORC5chr7

103767340

-
intron-intronENST00000473945ENST00000485726RELNchr7

103270387

-ORC5chr7

103767340

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000343529RELNchr7103175763-ENST00000545943ORC5chr7103767340-8060750910675542482
ENST00000428762RELNchr7103175763-ENST00000545943ORC5chr7103767340-8060750910675542482
ENST00000424685RELNchr7103175763-ENST00000545943ORC5chr7103767340-8060750910675542482
ENST00000343529RELNchr7103270387-ENST00000545943ORC5chr7103767340-341328621062907933
ENST00000428762RELNchr7103270387-ENST00000545943ORC5chr7103767340-341328621062907933
ENST00000424685RELNchr7103270387-ENST00000545943ORC5chr7103767340-341328621062907933

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000343529ENST00000545943RELNchr7103175763-ORC5chr7103767340-0.0004939170.9995061
ENST00000428762ENST00000545943RELNchr7103175763-ORC5chr7103767340-0.0004939170.9995061
ENST00000424685ENST00000545943RELNchr7103175763-ORC5chr7103767340-0.0004939170.9995061
ENST00000343529ENST00000545943RELNchr7103270387-ORC5chr7103767340-0.0003924570.9996076
ENST00000428762ENST00000545943RELNchr7103270387-ORC5chr7103767340-0.0003924570.9996076
ENST00000424685ENST00000545943RELNchr7103270387-ORC5chr7103767340-0.0003924570.9996076

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Fusion Genomic Features for RELN-ORC5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RELN-ORC5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:103270387/chr7:103767340)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46641029_106024493459.0DomainEGF-like 2
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46641408_144124493459.0DomainEGF-like 3
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46641764_179524493459.0DomainEGF-like 4
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46642128_216024493459.0DomainEGF-like 5
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-466426_19024493459.0DomainReelin
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-4664670_70124493459.0DomainEGF-like 1
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46651029_106024493461.0DomainEGF-like 2
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46651408_144124493461.0DomainEGF-like 3
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46651764_179524493461.0DomainEGF-like 4
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46652128_216024493461.0DomainEGF-like 5
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-466526_19024493461.0DomainReelin
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-4665670_70124493461.0DomainEGF-like 1
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-206426_1909003459.0DomainReelin
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-2064670_7019003459.0DomainEGF-like 1
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-206526_1909003461.0DomainReelin
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-2065670_7019003461.0DomainEGF-like 1
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46641156_116724493459.0RepeatNote=BNR 4
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46641322_133324493459.0RepeatNote=BNR 5
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46641534_154524493459.0RepeatNote=BNR 6
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46641685_169624493459.0RepeatNote=BNR 7
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46641883_189424493459.0RepeatNote=BNR 8
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46642042_205324493459.0RepeatNote=BNR 9
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46642249_226024493459.0RepeatNote=BNR 10
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46642398_240924493459.0RepeatNote=BNR 11
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-4664592_60324493459.0RepeatNote=BNR 1
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-4664798_80924493459.0RepeatNote=BNR 2
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-4664951_96224493459.0RepeatNote=BNR 3
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46651156_116724493461.0RepeatNote=BNR 4
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46651322_133324493461.0RepeatNote=BNR 5
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46651534_154524493461.0RepeatNote=BNR 6
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46651685_169624493461.0RepeatNote=BNR 7
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46651883_189424493461.0RepeatNote=BNR 8
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46652042_205324493461.0RepeatNote=BNR 9
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46652249_226024493461.0RepeatNote=BNR 10
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46652398_240924493461.0RepeatNote=BNR 11
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-4665592_60324493461.0RepeatNote=BNR 1
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-4665798_80924493461.0RepeatNote=BNR 2
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-4665951_96224493461.0RepeatNote=BNR 3
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-2064592_6039003459.0RepeatNote=BNR 1
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-2064798_8099003459.0RepeatNote=BNR 2
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-2065592_6039003461.0RepeatNote=BNR 1
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-2065798_8099003461.0RepeatNote=BNR 2
TgeneORC5chr7:103175763chr7:103767340ENST000004474520937_440325.0Nucleotide bindingATP
TgeneORC5chr7:103270387chr7:103767340ENST000004474520937_440325.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46643431_346024493459.0Compositional biasNote=Arg-rich (basic)
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46653431_346024493461.0Compositional biasNote=Arg-rich (basic)
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20643431_34609003459.0Compositional biasNote=Arg-rich (basic)
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20653431_34609003461.0Compositional biasNote=Arg-rich (basic)
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46642477_250824493459.0DomainEGF-like 6
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46642852_288324493459.0DomainEGF-like 7
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46643227_325924493459.0DomainEGF-like 8
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46652477_250824493461.0DomainEGF-like 6
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46652852_288324493461.0DomainEGF-like 7
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46653227_325924493461.0DomainEGF-like 8
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20641029_10609003459.0DomainEGF-like 2
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20641408_14419003459.0DomainEGF-like 3
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20641764_17959003459.0DomainEGF-like 4
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20642128_21609003459.0DomainEGF-like 5
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20642477_25089003459.0DomainEGF-like 6
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20642852_28839003459.0DomainEGF-like 7
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20643227_32599003459.0DomainEGF-like 8
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20651029_10609003461.0DomainEGF-like 2
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20651408_14419003461.0DomainEGF-like 3
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20651764_17959003461.0DomainEGF-like 4
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20652128_21609003461.0DomainEGF-like 5
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20652477_25089003461.0DomainEGF-like 6
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20652852_28839003461.0DomainEGF-like 7
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20653227_32599003461.0DomainEGF-like 8
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46642597_260824493459.0RepeatNote=BNR 12
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46642777_278824493459.0RepeatNote=BNR 13
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46642978_298924493459.0RepeatNote=BNR 14
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46643142_315424493459.0RepeatNote=BNR 15
HgeneRELNchr7:103175763chr7:103767340ENST00000343529-46643362_337324493459.0RepeatNote=BNR 16
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46652597_260824493461.0RepeatNote=BNR 12
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46652777_278824493461.0RepeatNote=BNR 13
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46652978_298924493461.0RepeatNote=BNR 14
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46653142_315424493461.0RepeatNote=BNR 15
HgeneRELNchr7:103175763chr7:103767340ENST00000428762-46653362_337324493461.0RepeatNote=BNR 16
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20641156_11679003459.0RepeatNote=BNR 4
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20641322_13339003459.0RepeatNote=BNR 5
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20641534_15459003459.0RepeatNote=BNR 6
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20641685_16969003459.0RepeatNote=BNR 7
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20641883_18949003459.0RepeatNote=BNR 8
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20642042_20539003459.0RepeatNote=BNR 9
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20642249_22609003459.0RepeatNote=BNR 10
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20642398_24099003459.0RepeatNote=BNR 11
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20642597_26089003459.0RepeatNote=BNR 12
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20642777_27889003459.0RepeatNote=BNR 13
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20642978_29899003459.0RepeatNote=BNR 14
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20643142_31549003459.0RepeatNote=BNR 15
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-20643362_33739003459.0RepeatNote=BNR 16
HgeneRELNchr7:103270387chr7:103767340ENST00000343529-2064951_9629003459.0RepeatNote=BNR 3
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20651156_11679003461.0RepeatNote=BNR 4
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20651322_13339003461.0RepeatNote=BNR 5
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20651534_15459003461.0RepeatNote=BNR 6
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20651685_16969003461.0RepeatNote=BNR 7
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20651883_18949003461.0RepeatNote=BNR 8
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20652042_20539003461.0RepeatNote=BNR 9
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20652249_22609003461.0RepeatNote=BNR 10
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20652398_24099003461.0RepeatNote=BNR 11
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20652597_26089003461.0RepeatNote=BNR 12
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20652777_27889003461.0RepeatNote=BNR 13
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20652978_29899003461.0RepeatNote=BNR 14
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20653142_31549003461.0RepeatNote=BNR 15
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-20653362_33739003461.0RepeatNote=BNR 16
HgeneRELNchr7:103270387chr7:103767340ENST00000428762-2065951_9629003461.0RepeatNote=BNR 3
TgeneORC5chr7:103175763chr7:103767340ENST00000297431121437_44420436.0Nucleotide bindingATP
TgeneORC5chr7:103270387chr7:103767340ENST00000297431121437_44420436.0Nucleotide bindingATP


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Fusion Gene Sequence for RELN-ORC5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>73451_73451_1_RELN-ORC5_RELN_chr7_103175763_ENST00000343529_ORC5_chr7_103767340_ENST00000545943_length(transcript)=8060nt_BP=7509nt
CTCGGCGGGGGCCCGCTCCCAGGCCCGCTCCCGAGCCCGTTCCGCTCCCGTCCGCCTTCTTCTCGCCTTCTCTCCGCGTGGCTCCTCCGT
CCCGGCGTCTCCAAAACTGAATGAGCGAGCGGCGCGTAGGGCGCGCGGCGGCGGCGGCGGCGGCGGCGGCATGGAGCGCAGTGGCTGGGC
CCGGCAGACTTTCCTCCTAGCGCTGTTGCTGGGGGCGACGCTGAGGGCGCGCGCGGCGGCTGGCTATTACCCCCGCTTTTCGCCCTTCTT
TTTCCTGTGCACCCACCACGGGGAGCTGGAAGGGGATGGGGAGCAGGGCGAGGTGCTCATTTCCCTGCATATTGCGGGCAACCCCACCTA
CTACGTTCCGGGACAAGAATACCATGTGACAATTTCAACAAGCACCTTTTTTGACGGCTTGCTGGTGACAGGACTATACACATCTACAAG
TGTTCAGGCATCACAGAGCATTGGAGGTTCCAGTGCTTTCGGATTTGGGATCATGTCTGACCACCAGTTTGGTAACCAGTTTATGTGCAG
TGTGGTAGCCTCTCACGTGAGTCACCTGCCCACAACCAACCTCAGTTTCATCTGGATTGCTCCACCTGCGGGCACAGGCTGTGTGAATTT
CATGGCTACAGCAACACACCGGGGCCAGGTTATTTTCAAAGATGCTTTAGCCCAGCAGTTGTGTGAACAAGGAGCTCCAACAGATGTCAC
TGTGCACCCACATCTAGCTGAAATACATAGTGACAGCATTATCCTGAGAGATGACTTTGACTCCTACCACCAACTGCAATTAAATCCAAA
TATATGGGTTGAATGTAACAACTGTGAGACTGGAGAACAGTGTGGCGCGATTATGCATGGCAATGCCGTCACCTTCTGTGAACCATATGG
CCCACGAGAACTGATTACCACAGGCCTTAATACAACAACAGCTTCTGTCCTCCAATTTTCCATTGGGTCAGGTTCATGTCGCTTTAGTTA
TTCAGACCCCAGCATCATCGTGTTATATGCCAAGAATAACTCTGCGGACTGGATTCAGCTAGAGAAAATTAGAGCCCCTTCCAATGTCAG
CACAATCATCCATATCCTCTACCTTCCTGAGGACGCCAAAGGGGAGAATGTCCAATTTCAGTGGAAGCAGGAAAATCTTCGTGTAGGTGA
AGTGTATGAAGCCTGCTGGGCCTTAGATAACATCTTGATCATCAATTCAGCTCACAGACAAGTCGTTTTAGAAGATAGTCTCGACCCAGT
GGACACAGGCAACTGGCTTTTCTTCCCAGGAGCTACAGTTAAGCATAGCTGTCAGTCAGATGGGAACTCCATTTATTTCCATGGAAATGA
AGGCAGCGAGTTCAATTTTGCCACCACCAGGGATGTAGATCTTTCCACAGAAGATATTCAAGAGCAATGGTCAGAAGAATTTGAGAGCCA
GCCTACAGGATGGGATGTCTTGGGAGCTGTCATTGGTACAGAATGTGGAACGATAGAATCAGGCTTATCAATGGTCTTCCTCAAAGATGG
AGAGAGGAAATTATGCACTCCATCCATGGACACTACCGGTTATGGGAACCTGAGGTTTTACTTTGTGATGGGAGGAATTTGTGACCCTGG
AAATTCTCATGAAAATGACATAATCCTGTATGCAAAAATTGAAGGAAGAAAAGAGCATATAACACTGGATACCCTTTCCTATTCCTCATA
TAAGGTTCCGTCTTTGGTTTCTGTGGTCATCAATCCTGAACTTCAGACTCCTGCTACCAAATTTTGTCTCAGGCAAAAGAACCATCAAGG
ACATAATAGGAATGTCTGGGCTGTAGACTTTTTCCATGTCTTGCCTGTTCTCCCTTCTACAATGTCTCACATGATACAGTTTTCCATCAA
TCTGGGATGTGGAACGCATCAGCCTGGTAACAGTGTCAGCTTGGAATTTTCTACCAACCATGGGCGCTCCTGGTCCCTCCTTCACACTGA
ATGCTTACCTGAGATCTGTGCTGGACCCCACCTCCCCCACAGCACTGTCTACTCCTCTGAAAACTACAGTGGGTGGAACCGAATAACAAT
TCCCCTTCCTAACGCAGCACTAACCCGGAACACCAGGATTCGCTGGAGACAAACAGGACCAATCCTTGGAAACATGTGGGCAATTGATAA
TGTTTATATTGGCCCGTCATGTCTCAAATTCTGTTCTGGCAGAGGACAGTGCACTAGACATGGTTGCAAGTGTGACCCTGGATTTTCTGG
CCCAGCTTGTGAGATGGCATCCCAGACATTCCCAATGTTTATTTCTGAAAGCTTTGGCAGTTCCAGGCTCTCCTCTTACCATAACTTTTA
CTCTATCCGTGGTGCTGAAGTCAGCTTTGGTTGTGGTGTCTTGGCCAGTGGTAAGGCCCTGGTTTTCAACAAAGATGGGCGGCGTCAGCT
AATTACATCTTTCCTTGACAGCTCACAATCCAGGTTTCTCCAGTTCACACTGAGACTGGGGAGCAAATCTGTTCTGAGCACGTGCAGAGC
CCCTGATCAGCCTGGTGAAGGAGTTTTGTTGCATTATTCTTATGATAATGGGATAACTTGGAAACTCCTGGAGCATTATTCATATCTCAG
CTATCATGAGCCCAGAATAATCTCCGTAGAACTACCAGGTGATGCAAAGCAGTTTGGAATTCAGTTCAGATGGTGGCAACCGTATCATTC
TTCCCAGAGAGAAGATGTATGGGCTATTGATGAGATTATCATGACATCTGTGCTTTTCAACAGCATTAGTCTTGACTTTACCAATCTTGT
GGAGGTCACTCAGTCTCTGGGATTCTACCTTGGAAATGTTCAGCCATACTGTGGCCACGACTGGACCCTTTGTTTTACAGGAGATTCTAA
ACTTGCCTCAAGTATGCGCTATGTGGAAACACAATCAATGCAGATAGGAGCATCCTATATGATTCAGTTCAGTTTGGTGATGGGATGTGG
CCAGAAATACACCCCACACATGGACAACCAGGTGAAGCTGGAGTACTCAACCAACCACGGCCTTACCTGGCACCTCGTCCAAGAAGAATG
CCTTCCAAGTATGCCAAGTTGTCAGGAATTTACATCAGCAAGTATTTACCATGCCAGTGAGTTTACACAGTGGAGGAGAGTCATAGTGCT
TCTTCCCCAGAAAACTTGGTCCAGTGCTACCCGTTTCCGCTGGAGCCAGAGCTATTACACAGCTCAAGACGAGTGGGCTTTGGACAGCAT
TTACATTGGGCAGCAGTGCCCCAACATGTGCAGTGGGCATGGCTCATGCGATCATGGCATATGCAGGTGTGACCAGGGGTACCAAGGCAC
TGAATGCCACCCAGAAGCTGCCCTTCCGTCCACAATTATGTCAGATTTTGAGAACCAGAATGGCTGGGAGTCTGACTGGCAAGAAGTTAT
TGGGGGAGAAATTGTAAAACCAGAACAAGGGTGTGGTGTCATCTCTTCTGGATCATCTCTGTACTTCAGCAAGGCTGGGAAAAGACAGCT
GGTGAGTTGGGACCTGGATACTTCTTGGGTGGACTTTGTCCAGTTCTACATCCAGATAGGCGGAGAGAGTGCTTCATGCAACAAGCCTGA
CAGCAGAGAGGAGGGCGTCCTCCTTCAGTACAGCAACAATGGGGGCATCCAGTGGCACCTGCTAGCAGAGATGTACTTTTCAGACTTCAG
CAAACCCAGATTTGTCTATCTGGAGCTTCCAGCTGCTGCCAAGACCCCTTGCACCAGGTTCCGCTGGTGGCAGCCCGTGTTCTCAGGGGA
GGACTATGACCAGTGGGCAGTCGATGACATCATCATTCTGTCCGAGAAGCAGAAGCAGATCATCCCAGTTATCAATCCAACTTTACCTCA
GAACTTTTATGAGAAGCCAGCTTTTGATTACCCTATGAATCAGATGAGTGTGTGGTTGATGTTGGCTAATGAAGGAATGGTTAAAAATGA
AACCTTCTGTGCTGCCACACCATCAGCAATGATATTTGGAAAATCAGATGGAGATCGATTTGCAGTAACTCGAGATTTGACCCTGAAACC
TGGATATGTGCTACAGTTCAAGCTAAACATAGGTTGTGCCAATCAATTCAGCAGTACTGCTCCAGTTCTTCTTCAGTACTCTCATGATGC
TGGTATGTCCTGGTTTCTGGTGAAAGAAGGCTGTTACCCGGCTTCTGCAGGCAAAGGATGCGAAGGAAACTCCAGAGAACTAAGTGAGCC
CACCATGTATCACACAGGGGACTTTGAAGAATGGACAAGAATCACCATTGTTATTCCAAGGTCTCTTGCATCCAGCAAGACCAGATTCCG
ATGGATCCAGGAGAGCAGCTCACAGAAAAACGTGCCTCCATTTGGTTTAGATGGAGTGTACATATCCGAGCCTTGTCCCAGTTACTGCAG
TGGCCATGGGGACTGCATTTCAGGAGTGTGTTTCTGTGACCTGGGATATACTGCTGCACAAGGAACCTGTGTGTCAAATGTCCCCAATCA
CAATGAGATGTTCGATAGGTTTGAGGGGAAGCTCAGCCCTCTGTGGTACAAGATAACAGGTGCCCAGGTTGGAACTGGCTGTGGAACACT
TAACGATGGCAAATCTCTCTACTTCAATGGCCCTGGGAAAAGGGAAGCCCGGACGGTCCCTCTGGACACCAGGAATATCAGACTTGTTCA
ATTTTATATACAAATTGGAAGCAAAACTTCAGGCATTACCTGCATCAAACCAAGAACTAGAAATGAAGGGCTTATTGTTCAGTATTCAAA
TGACAATGGGATACTCTGGCATTTGCTTCGAGAGTTGGACTTCATGTCCTTCCTGGAACCACAGATCATTTCCATTGACCTGCCACAGGA
CGCGAAGACACCTGCAACGGCATTTCGATGGTGGCAACCGCAACATGGGAAGCATTCAGCCCAGTGGGCTTTGGATGATGTTCTTATAGG
AATGAATGACAGCTCTCAAACTGGATTTCAAGACAAATTTGATGGCTCTATAGATTTGCAAGCCAACTGGTATCGAATCCAAGGAGGTCA
AGTTGATATTGACTGTCTCTCTATGGATACTGCTCTGATATTCACTGAAAACATAGGAAAACCTCGTTATGCTGAGACCTGGGATTTTCA
TGTGTCAGCATCTACCTTTTTGCAGTTTGAAATGAGCATGGGCTGTAGCAAGCCCTTCAGCAACTCCCACAGTGTACAGCTCCAGTATTC
TCTGAACAATGGCAAGGACTGGCATCTTGTCACCGAAGAGTGTGTTCCTCCAACCATTGGCTGTCTGCATTACACGGAAAGTTCAATTTA
CACCTCGGAAAGATTCCAGAATTGGAAGCGGATCACTGTCTACCTTCCACTCTCCACCATTTCTCCCAGGACCCGGTTCAGATGGATTCA
GGCCAACTACACTGTGGGGGCTGATTCCTGGGCGATTGATAATGTTGTACTGGCCTCAGGGTGCCCTTGGATGTGCTCAGGACGAGGGAT
TTGTGATGCTGGACGCTGTGTGTGTGACCGGGGCTTTGGTGGACCCTATTGTGTTCCTGTTGTTCCTCTGCCCTCGATTCTTAAAGACGA
TTTCAATGGGAATTTACATCCTGACCTTTGGCCTGAAGTGTATGGTGCAGAGAGGGGGAATCTGAATGGTGAAACCATCAAATCTGGAAC
ATCTCTAATTTTTAAAGGGGAAGGACTAAGGATGCTTATTTCAAGAGATCTAGATTGTACAAATACAATGTATGTCCAGTTTTCACTTAG
ATTTATAGCAAAAAGTACCCCAGAGAGATCTCACTCTATTCTGTTACAATTCTCCATCAGTGGAGGAATCACTTGGCACCTGATGGATGA
ATTTTACTTTCCTCAAACAACGAATATACTTTTCATCAATGTTCCCTTGCCATACACTGCCCAAACCAATGCTACAAGATTCAGACTCTG
GCAACCTTATAATAACGGTAAGAAAGAAGAAATCTGGATTGTTGATGACTTCATTATCGATGGAAATAATGTAAACAACCCTGTGATGCT
CTTGGATACATTTGATTTTGGGCCCAGAGAAGACAATTGGTTTTTCTATCCTGGTGGTAACATCGGTCTTTATTGTCCATATTCTTCAAA
GGGGGCACCTGAAGAAGATTCAGCTATGGTGTTTGTTTCAAATGAAGTTGGTGAGCATTCCATTACCACCCGTGACCTAAATGTGAATGA
GAACACCATCATACAATTTGAGATCAACGTTGGCTGTTCGACTGATAGCTCATCCGCGGATCCAGTGAGACTGGAATTTTCAAGGGACTT
CGGGGCGACCTGGCACCTTCTGCTGCCCCTCTGCTACCACAGCAGCAGCCACGTCAGCTCTTTATGCTCCACCGAGCACCACCCCAGCAG
CACCTACTACGCAGGAACCATGCAGGGCTGGAGGAGGGAGGTCGTGCACTTTGGGAAGCTGCACCTTTGTGGATCTGTCCGTTTCAGATG
GTACCAGGGATTTTACCCTGCCGGCTCTCAGCCAGTGACATGGGCCATTGATAATGTCTACATCGGTCCCCAGTGTGAGGAGATGTGTAA
TGGACAGGGGAGCTGTATCAATGGAACCAAATGTATATGTGACCCTGGCTACTCAGGTCCAACCTGTAAAATAAGCACCAAAAATCCTGA
TTTTCTCAAAGATGATTTCGAAGGTCAGCTAGAATCTGATAGATTCTTATTAATGAGTGGTGGGAAACCATCTCGAAAGTGTGGAATCCT
TTCTAGTGGAAACAACCTCTTTTTCAATGAAGATGGCTTGCGCATGTTGATGACACGAGACCTGGATTTATCACATGCTAGATTTGTGCA
GTTCTTCATGAGACTGGGATGTGGTAAAGGCGTTCCTGACCCCAGGAGTCAACCCGTGCTCCTACAGTATTCTCTCAACGGTGGCCTCTC
GTGGAGTCTTCTTCAGGAGTTCCTTTTCAGCAATTCCAGCAATGTGGGCAGGTACATTGCCCTGGAGATACCCTTGAAAGCCCGTTCTGG
TTCTACTCGCCTTCGCTGGTGGCAACCGTCTGAGAATGGGCACTTCTACAGCCCCTGGGTTATCGATCAGATTCTTATTGGAGGAAATAT
TTCTGGTAATACGGTCTTGGAAGATGATTTCACAACCCTTGATAGTAGGAAATGGCTGCTTCACCCAGGAGGCACCAAGATGCCCGTGTG
TGGCTCTACTGGTGATGCCCTGGTCTTCATTGAAAAGGCCAGCACCCGTTACGTGGTCAGCACAGACGTTGCCGTGAATGAGGATTCCTT
CCTACAGATAGACTTCGCTGCCTCCTGCTCAGTCACAGACTCTTGTTATGCGATTGAATTGGAATACTCAGTAGATCTTGGATTGTCATG
GCACCCATTGGTAAGGGACTGTCTGCCTACCAATGTGGAATGCAGTCGCTATCATCTGCAACGGATCCTGGTGTCAGACACTTTCAACAA
GTGGACTAGAATCACTCTGCCTCTCCCTCCTTATACCAGGACGGTGAACTTTGACATAATAAAATACTTGTATGATTTCTTGTGAAAACA
AGCTTCAAAGCCATATGGACACTGTGACAATGACTAAGCCAAGCTGTGTTCATCCAGCTACTTAGCTGGCCAAGGAGAGGAGTTCTTTGG
CTCTATTGGATTTGTCCAAACAGGTGCTGGCCCAGCATGGAATCTGATGAAAATATTCTGATTGGTCTGGGTGGATGTGAGCAGAAGACT
ATTTACCAGGGACCCTGGAGTATTTGGAAGCAACGTGTTAATTATAAACAGCAGGGTTTGAGCACAATCTGTTCTACTCTTAATGATGTT
ATCTTAACACTGAAATTGCCTGAAACCCATTTACTTAGGACTACATTTTGCTCTGTGAACTATCCCCTGCGCTTTGAACGTGCCAGCAGC
CCTTGTTTATATGCCCATTCTTTTCACTTCCTCTCCACAGGAGCCTCTGCAGTCGCTTGCCAAAGCAGATTTTCCTAAGGCCACTGTTTT

>73451_73451_1_RELN-ORC5_RELN_chr7_103175763_ENST00000343529_ORC5_chr7_103767340_ENST00000545943_length(amino acids)=2482AA_BP=2467
MNERAARRARGGGGGGGGMERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLHIAGNPTYYVPGQ
EYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQFGNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATAT
HRGQVIFKDALAQQLCEQGAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAVTFCEPYGPRELI
TTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKIRAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEAC
WALDNILIINSAHRQVVLEDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQWSEEFESQPTGWD
VLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVMGGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSL
VSVVINPELQTPATKFCLRQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRSWSLLHTECLPEI
CAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILGNMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEM
ASQTFPMFISESFGSSRLSSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKSVLSTCRAPDQPG
EGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFRWWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQS
LGFYLGNVQPYCGHDWTLCFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTWHLVQEECLPSMP
SCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQDEWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPE
AALPSTIMSDFENQNGWESDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGESASCNKPDSREEG
VLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWWQPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEK
PAFDYPMNQMSVWLMLANEGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVLLQYSHDAGMSWF
LVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLASSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDC
ISGVCFCDLGYTAAQGTCVSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDTRNIRLVQFYIQI
GSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQIISIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSS
QTGFQDKFDGSIDLQANWYRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSHSVQLQYSLNNGK
DWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPRTRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGR
CVCDRGFGGPYCVPVVPLPSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTMYVQFSLRFIAKS
TPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTNATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFD
FGPREDNWFFYPGGNIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWH
LLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLCGSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSC
INGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDLSHARFVQFFMRL
GCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEIPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTV
LEDDFTTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVR

--------------------------------------------------------------
>73451_73451_2_RELN-ORC5_RELN_chr7_103175763_ENST00000424685_ORC5_chr7_103767340_ENST00000545943_length(transcript)=8060nt_BP=7509nt
CTCGGCGGGGGCCCGCTCCCAGGCCCGCTCCCGAGCCCGTTCCGCTCCCGTCCGCCTTCTTCTCGCCTTCTCTCCGCGTGGCTCCTCCGT
CCCGGCGTCTCCAAAACTGAATGAGCGAGCGGCGCGTAGGGCGCGCGGCGGCGGCGGCGGCGGCGGCGGCATGGAGCGCAGTGGCTGGGC
CCGGCAGACTTTCCTCCTAGCGCTGTTGCTGGGGGCGACGCTGAGGGCGCGCGCGGCGGCTGGCTATTACCCCCGCTTTTCGCCCTTCTT
TTTCCTGTGCACCCACCACGGGGAGCTGGAAGGGGATGGGGAGCAGGGCGAGGTGCTCATTTCCCTGCATATTGCGGGCAACCCCACCTA
CTACGTTCCGGGACAAGAATACCATGTGACAATTTCAACAAGCACCTTTTTTGACGGCTTGCTGGTGACAGGACTATACACATCTACAAG
TGTTCAGGCATCACAGAGCATTGGAGGTTCCAGTGCTTTCGGATTTGGGATCATGTCTGACCACCAGTTTGGTAACCAGTTTATGTGCAG
TGTGGTAGCCTCTCACGTGAGTCACCTGCCCACAACCAACCTCAGTTTCATCTGGATTGCTCCACCTGCGGGCACAGGCTGTGTGAATTT
CATGGCTACAGCAACACACCGGGGCCAGGTTATTTTCAAAGATGCTTTAGCCCAGCAGTTGTGTGAACAAGGAGCTCCAACAGATGTCAC
TGTGCACCCACATCTAGCTGAAATACATAGTGACAGCATTATCCTGAGAGATGACTTTGACTCCTACCACCAACTGCAATTAAATCCAAA
TATATGGGTTGAATGTAACAACTGTGAGACTGGAGAACAGTGTGGCGCGATTATGCATGGCAATGCCGTCACCTTCTGTGAACCATATGG
CCCACGAGAACTGATTACCACAGGCCTTAATACAACAACAGCTTCTGTCCTCCAATTTTCCATTGGGTCAGGTTCATGTCGCTTTAGTTA
TTCAGACCCCAGCATCATCGTGTTATATGCCAAGAATAACTCTGCGGACTGGATTCAGCTAGAGAAAATTAGAGCCCCTTCCAATGTCAG
CACAATCATCCATATCCTCTACCTTCCTGAGGACGCCAAAGGGGAGAATGTCCAATTTCAGTGGAAGCAGGAAAATCTTCGTGTAGGTGA
AGTGTATGAAGCCTGCTGGGCCTTAGATAACATCTTGATCATCAATTCAGCTCACAGACAAGTCGTTTTAGAAGATAGTCTCGACCCAGT
GGACACAGGCAACTGGCTTTTCTTCCCAGGAGCTACAGTTAAGCATAGCTGTCAGTCAGATGGGAACTCCATTTATTTCCATGGAAATGA
AGGCAGCGAGTTCAATTTTGCCACCACCAGGGATGTAGATCTTTCCACAGAAGATATTCAAGAGCAATGGTCAGAAGAATTTGAGAGCCA
GCCTACAGGATGGGATGTCTTGGGAGCTGTCATTGGTACAGAATGTGGAACGATAGAATCAGGCTTATCAATGGTCTTCCTCAAAGATGG
AGAGAGGAAATTATGCACTCCATCCATGGACACTACCGGTTATGGGAACCTGAGGTTTTACTTTGTGATGGGAGGAATTTGTGACCCTGG
AAATTCTCATGAAAATGACATAATCCTGTATGCAAAAATTGAAGGAAGAAAAGAGCATATAACACTGGATACCCTTTCCTATTCCTCATA
TAAGGTTCCGTCTTTGGTTTCTGTGGTCATCAATCCTGAACTTCAGACTCCTGCTACCAAATTTTGTCTCAGGCAAAAGAACCATCAAGG
ACATAATAGGAATGTCTGGGCTGTAGACTTTTTCCATGTCTTGCCTGTTCTCCCTTCTACAATGTCTCACATGATACAGTTTTCCATCAA
TCTGGGATGTGGAACGCATCAGCCTGGTAACAGTGTCAGCTTGGAATTTTCTACCAACCATGGGCGCTCCTGGTCCCTCCTTCACACTGA
ATGCTTACCTGAGATCTGTGCTGGACCCCACCTCCCCCACAGCACTGTCTACTCCTCTGAAAACTACAGTGGGTGGAACCGAATAACAAT
TCCCCTTCCTAACGCAGCACTAACCCGGAACACCAGGATTCGCTGGAGACAAACAGGACCAATCCTTGGAAACATGTGGGCAATTGATAA
TGTTTATATTGGCCCGTCATGTCTCAAATTCTGTTCTGGCAGAGGACAGTGCACTAGACATGGTTGCAAGTGTGACCCTGGATTTTCTGG
CCCAGCTTGTGAGATGGCATCCCAGACATTCCCAATGTTTATTTCTGAAAGCTTTGGCAGTTCCAGGCTCTCCTCTTACCATAACTTTTA
CTCTATCCGTGGTGCTGAAGTCAGCTTTGGTTGTGGTGTCTTGGCCAGTGGTAAGGCCCTGGTTTTCAACAAAGATGGGCGGCGTCAGCT
AATTACATCTTTCCTTGACAGCTCACAATCCAGGTTTCTCCAGTTCACACTGAGACTGGGGAGCAAATCTGTTCTGAGCACGTGCAGAGC
CCCTGATCAGCCTGGTGAAGGAGTTTTGTTGCATTATTCTTATGATAATGGGATAACTTGGAAACTCCTGGAGCATTATTCATATCTCAG
CTATCATGAGCCCAGAATAATCTCCGTAGAACTACCAGGTGATGCAAAGCAGTTTGGAATTCAGTTCAGATGGTGGCAACCGTATCATTC
TTCCCAGAGAGAAGATGTATGGGCTATTGATGAGATTATCATGACATCTGTGCTTTTCAACAGCATTAGTCTTGACTTTACCAATCTTGT
GGAGGTCACTCAGTCTCTGGGATTCTACCTTGGAAATGTTCAGCCATACTGTGGCCACGACTGGACCCTTTGTTTTACAGGAGATTCTAA
ACTTGCCTCAAGTATGCGCTATGTGGAAACACAATCAATGCAGATAGGAGCATCCTATATGATTCAGTTCAGTTTGGTGATGGGATGTGG
CCAGAAATACACCCCACACATGGACAACCAGGTGAAGCTGGAGTACTCAACCAACCACGGCCTTACCTGGCACCTCGTCCAAGAAGAATG
CCTTCCAAGTATGCCAAGTTGTCAGGAATTTACATCAGCAAGTATTTACCATGCCAGTGAGTTTACACAGTGGAGGAGAGTCATAGTGCT
TCTTCCCCAGAAAACTTGGTCCAGTGCTACCCGTTTCCGCTGGAGCCAGAGCTATTACACAGCTCAAGACGAGTGGGCTTTGGACAGCAT
TTACATTGGGCAGCAGTGCCCCAACATGTGCAGTGGGCATGGCTCATGCGATCATGGCATATGCAGGTGTGACCAGGGGTACCAAGGCAC
TGAATGCCACCCAGAAGCTGCCCTTCCGTCCACAATTATGTCAGATTTTGAGAACCAGAATGGCTGGGAGTCTGACTGGCAAGAAGTTAT
TGGGGGAGAAATTGTAAAACCAGAACAAGGGTGTGGTGTCATCTCTTCTGGATCATCTCTGTACTTCAGCAAGGCTGGGAAAAGACAGCT
GGTGAGTTGGGACCTGGATACTTCTTGGGTGGACTTTGTCCAGTTCTACATCCAGATAGGCGGAGAGAGTGCTTCATGCAACAAGCCTGA
CAGCAGAGAGGAGGGCGTCCTCCTTCAGTACAGCAACAATGGGGGCATCCAGTGGCACCTGCTAGCAGAGATGTACTTTTCAGACTTCAG
CAAACCCAGATTTGTCTATCTGGAGCTTCCAGCTGCTGCCAAGACCCCTTGCACCAGGTTCCGCTGGTGGCAGCCCGTGTTCTCAGGGGA
GGACTATGACCAGTGGGCAGTCGATGACATCATCATTCTGTCCGAGAAGCAGAAGCAGATCATCCCAGTTATCAATCCAACTTTACCTCA
GAACTTTTATGAGAAGCCAGCTTTTGATTACCCTATGAATCAGATGAGTGTGTGGTTGATGTTGGCTAATGAAGGAATGGTTAAAAATGA
AACCTTCTGTGCTGCCACACCATCAGCAATGATATTTGGAAAATCAGATGGAGATCGATTTGCAGTAACTCGAGATTTGACCCTGAAACC
TGGATATGTGCTACAGTTCAAGCTAAACATAGGTTGTGCCAATCAATTCAGCAGTACTGCTCCAGTTCTTCTTCAGTACTCTCATGATGC
TGGTATGTCCTGGTTTCTGGTGAAAGAAGGCTGTTACCCGGCTTCTGCAGGCAAAGGATGCGAAGGAAACTCCAGAGAACTAAGTGAGCC
CACCATGTATCACACAGGGGACTTTGAAGAATGGACAAGAATCACCATTGTTATTCCAAGGTCTCTTGCATCCAGCAAGACCAGATTCCG
ATGGATCCAGGAGAGCAGCTCACAGAAAAACGTGCCTCCATTTGGTTTAGATGGAGTGTACATATCCGAGCCTTGTCCCAGTTACTGCAG
TGGCCATGGGGACTGCATTTCAGGAGTGTGTTTCTGTGACCTGGGATATACTGCTGCACAAGGAACCTGTGTGTCAAATGTCCCCAATCA
CAATGAGATGTTCGATAGGTTTGAGGGGAAGCTCAGCCCTCTGTGGTACAAGATAACAGGTGCCCAGGTTGGAACTGGCTGTGGAACACT
TAACGATGGCAAATCTCTCTACTTCAATGGCCCTGGGAAAAGGGAAGCCCGGACGGTCCCTCTGGACACCAGGAATATCAGACTTGTTCA
ATTTTATATACAAATTGGAAGCAAAACTTCAGGCATTACCTGCATCAAACCAAGAACTAGAAATGAAGGGCTTATTGTTCAGTATTCAAA
TGACAATGGGATACTCTGGCATTTGCTTCGAGAGTTGGACTTCATGTCCTTCCTGGAACCACAGATCATTTCCATTGACCTGCCACAGGA
CGCGAAGACACCTGCAACGGCATTTCGATGGTGGCAACCGCAACATGGGAAGCATTCAGCCCAGTGGGCTTTGGATGATGTTCTTATAGG
AATGAATGACAGCTCTCAAACTGGATTTCAAGACAAATTTGATGGCTCTATAGATTTGCAAGCCAACTGGTATCGAATCCAAGGAGGTCA
AGTTGATATTGACTGTCTCTCTATGGATACTGCTCTGATATTCACTGAAAACATAGGAAAACCTCGTTATGCTGAGACCTGGGATTTTCA
TGTGTCAGCATCTACCTTTTTGCAGTTTGAAATGAGCATGGGCTGTAGCAAGCCCTTCAGCAACTCCCACAGTGTACAGCTCCAGTATTC
TCTGAACAATGGCAAGGACTGGCATCTTGTCACCGAAGAGTGTGTTCCTCCAACCATTGGCTGTCTGCATTACACGGAAAGTTCAATTTA
CACCTCGGAAAGATTCCAGAATTGGAAGCGGATCACTGTCTACCTTCCACTCTCCACCATTTCTCCCAGGACCCGGTTCAGATGGATTCA
GGCCAACTACACTGTGGGGGCTGATTCCTGGGCGATTGATAATGTTGTACTGGCCTCAGGGTGCCCTTGGATGTGCTCAGGACGAGGGAT
TTGTGATGCTGGACGCTGTGTGTGTGACCGGGGCTTTGGTGGACCCTATTGTGTTCCTGTTGTTCCTCTGCCCTCGATTCTTAAAGACGA
TTTCAATGGGAATTTACATCCTGACCTTTGGCCTGAAGTGTATGGTGCAGAGAGGGGGAATCTGAATGGTGAAACCATCAAATCTGGAAC
ATCTCTAATTTTTAAAGGGGAAGGACTAAGGATGCTTATTTCAAGAGATCTAGATTGTACAAATACAATGTATGTCCAGTTTTCACTTAG
ATTTATAGCAAAAAGTACCCCAGAGAGATCTCACTCTATTCTGTTACAATTCTCCATCAGTGGAGGAATCACTTGGCACCTGATGGATGA
ATTTTACTTTCCTCAAACAACGAATATACTTTTCATCAATGTTCCCTTGCCATACACTGCCCAAACCAATGCTACAAGATTCAGACTCTG
GCAACCTTATAATAACGGTAAGAAAGAAGAAATCTGGATTGTTGATGACTTCATTATCGATGGAAATAATGTAAACAACCCTGTGATGCT
CTTGGATACATTTGATTTTGGGCCCAGAGAAGACAATTGGTTTTTCTATCCTGGTGGTAACATCGGTCTTTATTGTCCATATTCTTCAAA
GGGGGCACCTGAAGAAGATTCAGCTATGGTGTTTGTTTCAAATGAAGTTGGTGAGCATTCCATTACCACCCGTGACCTAAATGTGAATGA
GAACACCATCATACAATTTGAGATCAACGTTGGCTGTTCGACTGATAGCTCATCCGCGGATCCAGTGAGACTGGAATTTTCAAGGGACTT
CGGGGCGACCTGGCACCTTCTGCTGCCCCTCTGCTACCACAGCAGCAGCCACGTCAGCTCTTTATGCTCCACCGAGCACCACCCCAGCAG
CACCTACTACGCAGGAACCATGCAGGGCTGGAGGAGGGAGGTCGTGCACTTTGGGAAGCTGCACCTTTGTGGATCTGTCCGTTTCAGATG
GTACCAGGGATTTTACCCTGCCGGCTCTCAGCCAGTGACATGGGCCATTGATAATGTCTACATCGGTCCCCAGTGTGAGGAGATGTGTAA
TGGACAGGGGAGCTGTATCAATGGAACCAAATGTATATGTGACCCTGGCTACTCAGGTCCAACCTGTAAAATAAGCACCAAAAATCCTGA
TTTTCTCAAAGATGATTTCGAAGGTCAGCTAGAATCTGATAGATTCTTATTAATGAGTGGTGGGAAACCATCTCGAAAGTGTGGAATCCT
TTCTAGTGGAAACAACCTCTTTTTCAATGAAGATGGCTTGCGCATGTTGATGACACGAGACCTGGATTTATCACATGCTAGATTTGTGCA
GTTCTTCATGAGACTGGGATGTGGTAAAGGCGTTCCTGACCCCAGGAGTCAACCCGTGCTCCTACAGTATTCTCTCAACGGTGGCCTCTC
GTGGAGTCTTCTTCAGGAGTTCCTTTTCAGCAATTCCAGCAATGTGGGCAGGTACATTGCCCTGGAGATACCCTTGAAAGCCCGTTCTGG
TTCTACTCGCCTTCGCTGGTGGCAACCGTCTGAGAATGGGCACTTCTACAGCCCCTGGGTTATCGATCAGATTCTTATTGGAGGAAATAT
TTCTGGTAATACGGTCTTGGAAGATGATTTCACAACCCTTGATAGTAGGAAATGGCTGCTTCACCCAGGAGGCACCAAGATGCCCGTGTG
TGGCTCTACTGGTGATGCCCTGGTCTTCATTGAAAAGGCCAGCACCCGTTACGTGGTCAGCACAGACGTTGCCGTGAATGAGGATTCCTT
CCTACAGATAGACTTCGCTGCCTCCTGCTCAGTCACAGACTCTTGTTATGCGATTGAATTGGAATACTCAGTAGATCTTGGATTGTCATG
GCACCCATTGGTAAGGGACTGTCTGCCTACCAATGTGGAATGCAGTCGCTATCATCTGCAACGGATCCTGGTGTCAGACACTTTCAACAA
GTGGACTAGAATCACTCTGCCTCTCCCTCCTTATACCAGGACGGTGAACTTTGACATAATAAAATACTTGTATGATTTCTTGTGAAAACA
AGCTTCAAAGCCATATGGACACTGTGACAATGACTAAGCCAAGCTGTGTTCATCCAGCTACTTAGCTGGCCAAGGAGAGGAGTTCTTTGG
CTCTATTGGATTTGTCCAAACAGGTGCTGGCCCAGCATGGAATCTGATGAAAATATTCTGATTGGTCTGGGTGGATGTGAGCAGAAGACT
ATTTACCAGGGACCCTGGAGTATTTGGAAGCAACGTGTTAATTATAAACAGCAGGGTTTGAGCACAATCTGTTCTACTCTTAATGATGTT
ATCTTAACACTGAAATTGCCTGAAACCCATTTACTTAGGACTACATTTTGCTCTGTGAACTATCCCCTGCGCTTTGAACGTGCCAGCAGC
CCTTGTTTATATGCCCATTCTTTTCACTTCCTCTCCACAGGAGCCTCTGCAGTCGCTTGCCAAAGCAGATTTTCCTAAGGCCACTGTTTT

>73451_73451_2_RELN-ORC5_RELN_chr7_103175763_ENST00000424685_ORC5_chr7_103767340_ENST00000545943_length(amino acids)=2482AA_BP=2467
MNERAARRARGGGGGGGGMERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLHIAGNPTYYVPGQ
EYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQFGNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATAT
HRGQVIFKDALAQQLCEQGAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAVTFCEPYGPRELI
TTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKIRAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEAC
WALDNILIINSAHRQVVLEDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQWSEEFESQPTGWD
VLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVMGGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSL
VSVVINPELQTPATKFCLRQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRSWSLLHTECLPEI
CAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILGNMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEM
ASQTFPMFISESFGSSRLSSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKSVLSTCRAPDQPG
EGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFRWWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQS
LGFYLGNVQPYCGHDWTLCFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTWHLVQEECLPSMP
SCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQDEWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPE
AALPSTIMSDFENQNGWESDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGESASCNKPDSREEG
VLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWWQPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEK
PAFDYPMNQMSVWLMLANEGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVLLQYSHDAGMSWF
LVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLASSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDC
ISGVCFCDLGYTAAQGTCVSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDTRNIRLVQFYIQI
GSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQIISIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSS
QTGFQDKFDGSIDLQANWYRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSHSVQLQYSLNNGK
DWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPRTRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGR
CVCDRGFGGPYCVPVVPLPSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTMYVQFSLRFIAKS
TPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTNATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFD
FGPREDNWFFYPGGNIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWH
LLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLCGSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSC
INGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDLSHARFVQFFMRL
GCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEIPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTV
LEDDFTTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVR

--------------------------------------------------------------
>73451_73451_3_RELN-ORC5_RELN_chr7_103175763_ENST00000428762_ORC5_chr7_103767340_ENST00000545943_length(transcript)=8060nt_BP=7509nt
CTCGGCGGGGGCCCGCTCCCAGGCCCGCTCCCGAGCCCGTTCCGCTCCCGTCCGCCTTCTTCTCGCCTTCTCTCCGCGTGGCTCCTCCGT
CCCGGCGTCTCCAAAACTGAATGAGCGAGCGGCGCGTAGGGCGCGCGGCGGCGGCGGCGGCGGCGGCGGCATGGAGCGCAGTGGCTGGGC
CCGGCAGACTTTCCTCCTAGCGCTGTTGCTGGGGGCGACGCTGAGGGCGCGCGCGGCGGCTGGCTATTACCCCCGCTTTTCGCCCTTCTT
TTTCCTGTGCACCCACCACGGGGAGCTGGAAGGGGATGGGGAGCAGGGCGAGGTGCTCATTTCCCTGCATATTGCGGGCAACCCCACCTA
CTACGTTCCGGGACAAGAATACCATGTGACAATTTCAACAAGCACCTTTTTTGACGGCTTGCTGGTGACAGGACTATACACATCTACAAG
TGTTCAGGCATCACAGAGCATTGGAGGTTCCAGTGCTTTCGGATTTGGGATCATGTCTGACCACCAGTTTGGTAACCAGTTTATGTGCAG
TGTGGTAGCCTCTCACGTGAGTCACCTGCCCACAACCAACCTCAGTTTCATCTGGATTGCTCCACCTGCGGGCACAGGCTGTGTGAATTT
CATGGCTACAGCAACACACCGGGGCCAGGTTATTTTCAAAGATGCTTTAGCCCAGCAGTTGTGTGAACAAGGAGCTCCAACAGATGTCAC
TGTGCACCCACATCTAGCTGAAATACATAGTGACAGCATTATCCTGAGAGATGACTTTGACTCCTACCACCAACTGCAATTAAATCCAAA
TATATGGGTTGAATGTAACAACTGTGAGACTGGAGAACAGTGTGGCGCGATTATGCATGGCAATGCCGTCACCTTCTGTGAACCATATGG
CCCACGAGAACTGATTACCACAGGCCTTAATACAACAACAGCTTCTGTCCTCCAATTTTCCATTGGGTCAGGTTCATGTCGCTTTAGTTA
TTCAGACCCCAGCATCATCGTGTTATATGCCAAGAATAACTCTGCGGACTGGATTCAGCTAGAGAAAATTAGAGCCCCTTCCAATGTCAG
CACAATCATCCATATCCTCTACCTTCCTGAGGACGCCAAAGGGGAGAATGTCCAATTTCAGTGGAAGCAGGAAAATCTTCGTGTAGGTGA
AGTGTATGAAGCCTGCTGGGCCTTAGATAACATCTTGATCATCAATTCAGCTCACAGACAAGTCGTTTTAGAAGATAGTCTCGACCCAGT
GGACACAGGCAACTGGCTTTTCTTCCCAGGAGCTACAGTTAAGCATAGCTGTCAGTCAGATGGGAACTCCATTTATTTCCATGGAAATGA
AGGCAGCGAGTTCAATTTTGCCACCACCAGGGATGTAGATCTTTCCACAGAAGATATTCAAGAGCAATGGTCAGAAGAATTTGAGAGCCA
GCCTACAGGATGGGATGTCTTGGGAGCTGTCATTGGTACAGAATGTGGAACGATAGAATCAGGCTTATCAATGGTCTTCCTCAAAGATGG
AGAGAGGAAATTATGCACTCCATCCATGGACACTACCGGTTATGGGAACCTGAGGTTTTACTTTGTGATGGGAGGAATTTGTGACCCTGG
AAATTCTCATGAAAATGACATAATCCTGTATGCAAAAATTGAAGGAAGAAAAGAGCATATAACACTGGATACCCTTTCCTATTCCTCATA
TAAGGTTCCGTCTTTGGTTTCTGTGGTCATCAATCCTGAACTTCAGACTCCTGCTACCAAATTTTGTCTCAGGCAAAAGAACCATCAAGG
ACATAATAGGAATGTCTGGGCTGTAGACTTTTTCCATGTCTTGCCTGTTCTCCCTTCTACAATGTCTCACATGATACAGTTTTCCATCAA
TCTGGGATGTGGAACGCATCAGCCTGGTAACAGTGTCAGCTTGGAATTTTCTACCAACCATGGGCGCTCCTGGTCCCTCCTTCACACTGA
ATGCTTACCTGAGATCTGTGCTGGACCCCACCTCCCCCACAGCACTGTCTACTCCTCTGAAAACTACAGTGGGTGGAACCGAATAACAAT
TCCCCTTCCTAACGCAGCACTAACCCGGAACACCAGGATTCGCTGGAGACAAACAGGACCAATCCTTGGAAACATGTGGGCAATTGATAA
TGTTTATATTGGCCCGTCATGTCTCAAATTCTGTTCTGGCAGAGGACAGTGCACTAGACATGGTTGCAAGTGTGACCCTGGATTTTCTGG
CCCAGCTTGTGAGATGGCATCCCAGACATTCCCAATGTTTATTTCTGAAAGCTTTGGCAGTTCCAGGCTCTCCTCTTACCATAACTTTTA
CTCTATCCGTGGTGCTGAAGTCAGCTTTGGTTGTGGTGTCTTGGCCAGTGGTAAGGCCCTGGTTTTCAACAAAGATGGGCGGCGTCAGCT
AATTACATCTTTCCTTGACAGCTCACAATCCAGGTTTCTCCAGTTCACACTGAGACTGGGGAGCAAATCTGTTCTGAGCACGTGCAGAGC
CCCTGATCAGCCTGGTGAAGGAGTTTTGTTGCATTATTCTTATGATAATGGGATAACTTGGAAACTCCTGGAGCATTATTCATATCTCAG
CTATCATGAGCCCAGAATAATCTCCGTAGAACTACCAGGTGATGCAAAGCAGTTTGGAATTCAGTTCAGATGGTGGCAACCGTATCATTC
TTCCCAGAGAGAAGATGTATGGGCTATTGATGAGATTATCATGACATCTGTGCTTTTCAACAGCATTAGTCTTGACTTTACCAATCTTGT
GGAGGTCACTCAGTCTCTGGGATTCTACCTTGGAAATGTTCAGCCATACTGTGGCCACGACTGGACCCTTTGTTTTACAGGAGATTCTAA
ACTTGCCTCAAGTATGCGCTATGTGGAAACACAATCAATGCAGATAGGAGCATCCTATATGATTCAGTTCAGTTTGGTGATGGGATGTGG
CCAGAAATACACCCCACACATGGACAACCAGGTGAAGCTGGAGTACTCAACCAACCACGGCCTTACCTGGCACCTCGTCCAAGAAGAATG
CCTTCCAAGTATGCCAAGTTGTCAGGAATTTACATCAGCAAGTATTTACCATGCCAGTGAGTTTACACAGTGGAGGAGAGTCATAGTGCT
TCTTCCCCAGAAAACTTGGTCCAGTGCTACCCGTTTCCGCTGGAGCCAGAGCTATTACACAGCTCAAGACGAGTGGGCTTTGGACAGCAT
TTACATTGGGCAGCAGTGCCCCAACATGTGCAGTGGGCATGGCTCATGCGATCATGGCATATGCAGGTGTGACCAGGGGTACCAAGGCAC
TGAATGCCACCCAGAAGCTGCCCTTCCGTCCACAATTATGTCAGATTTTGAGAACCAGAATGGCTGGGAGTCTGACTGGCAAGAAGTTAT
TGGGGGAGAAATTGTAAAACCAGAACAAGGGTGTGGTGTCATCTCTTCTGGATCATCTCTGTACTTCAGCAAGGCTGGGAAAAGACAGCT
GGTGAGTTGGGACCTGGATACTTCTTGGGTGGACTTTGTCCAGTTCTACATCCAGATAGGCGGAGAGAGTGCTTCATGCAACAAGCCTGA
CAGCAGAGAGGAGGGCGTCCTCCTTCAGTACAGCAACAATGGGGGCATCCAGTGGCACCTGCTAGCAGAGATGTACTTTTCAGACTTCAG
CAAACCCAGATTTGTCTATCTGGAGCTTCCAGCTGCTGCCAAGACCCCTTGCACCAGGTTCCGCTGGTGGCAGCCCGTGTTCTCAGGGGA
GGACTATGACCAGTGGGCAGTCGATGACATCATCATTCTGTCCGAGAAGCAGAAGCAGATCATCCCAGTTATCAATCCAACTTTACCTCA
GAACTTTTATGAGAAGCCAGCTTTTGATTACCCTATGAATCAGATGAGTGTGTGGTTGATGTTGGCTAATGAAGGAATGGTTAAAAATGA
AACCTTCTGTGCTGCCACACCATCAGCAATGATATTTGGAAAATCAGATGGAGATCGATTTGCAGTAACTCGAGATTTGACCCTGAAACC
TGGATATGTGCTACAGTTCAAGCTAAACATAGGTTGTGCCAATCAATTCAGCAGTACTGCTCCAGTTCTTCTTCAGTACTCTCATGATGC
TGGTATGTCCTGGTTTCTGGTGAAAGAAGGCTGTTACCCGGCTTCTGCAGGCAAAGGATGCGAAGGAAACTCCAGAGAACTAAGTGAGCC
CACCATGTATCACACAGGGGACTTTGAAGAATGGACAAGAATCACCATTGTTATTCCAAGGTCTCTTGCATCCAGCAAGACCAGATTCCG
ATGGATCCAGGAGAGCAGCTCACAGAAAAACGTGCCTCCATTTGGTTTAGATGGAGTGTACATATCCGAGCCTTGTCCCAGTTACTGCAG
TGGCCATGGGGACTGCATTTCAGGAGTGTGTTTCTGTGACCTGGGATATACTGCTGCACAAGGAACCTGTGTGTCAAATGTCCCCAATCA
CAATGAGATGTTCGATAGGTTTGAGGGGAAGCTCAGCCCTCTGTGGTACAAGATAACAGGTGCCCAGGTTGGAACTGGCTGTGGAACACT
TAACGATGGCAAATCTCTCTACTTCAATGGCCCTGGGAAAAGGGAAGCCCGGACGGTCCCTCTGGACACCAGGAATATCAGACTTGTTCA
ATTTTATATACAAATTGGAAGCAAAACTTCAGGCATTACCTGCATCAAACCAAGAACTAGAAATGAAGGGCTTATTGTTCAGTATTCAAA
TGACAATGGGATACTCTGGCATTTGCTTCGAGAGTTGGACTTCATGTCCTTCCTGGAACCACAGATCATTTCCATTGACCTGCCACAGGA
CGCGAAGACACCTGCAACGGCATTTCGATGGTGGCAACCGCAACATGGGAAGCATTCAGCCCAGTGGGCTTTGGATGATGTTCTTATAGG
AATGAATGACAGCTCTCAAACTGGATTTCAAGACAAATTTGATGGCTCTATAGATTTGCAAGCCAACTGGTATCGAATCCAAGGAGGTCA
AGTTGATATTGACTGTCTCTCTATGGATACTGCTCTGATATTCACTGAAAACATAGGAAAACCTCGTTATGCTGAGACCTGGGATTTTCA
TGTGTCAGCATCTACCTTTTTGCAGTTTGAAATGAGCATGGGCTGTAGCAAGCCCTTCAGCAACTCCCACAGTGTACAGCTCCAGTATTC
TCTGAACAATGGCAAGGACTGGCATCTTGTCACCGAAGAGTGTGTTCCTCCAACCATTGGCTGTCTGCATTACACGGAAAGTTCAATTTA
CACCTCGGAAAGATTCCAGAATTGGAAGCGGATCACTGTCTACCTTCCACTCTCCACCATTTCTCCCAGGACCCGGTTCAGATGGATTCA
GGCCAACTACACTGTGGGGGCTGATTCCTGGGCGATTGATAATGTTGTACTGGCCTCAGGGTGCCCTTGGATGTGCTCAGGACGAGGGAT
TTGTGATGCTGGACGCTGTGTGTGTGACCGGGGCTTTGGTGGACCCTATTGTGTTCCTGTTGTTCCTCTGCCCTCGATTCTTAAAGACGA
TTTCAATGGGAATTTACATCCTGACCTTTGGCCTGAAGTGTATGGTGCAGAGAGGGGGAATCTGAATGGTGAAACCATCAAATCTGGAAC
ATCTCTAATTTTTAAAGGGGAAGGACTAAGGATGCTTATTTCAAGAGATCTAGATTGTACAAATACAATGTATGTCCAGTTTTCACTTAG
ATTTATAGCAAAAAGTACCCCAGAGAGATCTCACTCTATTCTGTTACAATTCTCCATCAGTGGAGGAATCACTTGGCACCTGATGGATGA
ATTTTACTTTCCTCAAACAACGAATATACTTTTCATCAATGTTCCCTTGCCATACACTGCCCAAACCAATGCTACAAGATTCAGACTCTG
GCAACCTTATAATAACGGTAAGAAAGAAGAAATCTGGATTGTTGATGACTTCATTATCGATGGAAATAATGTAAACAACCCTGTGATGCT
CTTGGATACATTTGATTTTGGGCCCAGAGAAGACAATTGGTTTTTCTATCCTGGTGGTAACATCGGTCTTTATTGTCCATATTCTTCAAA
GGGGGCACCTGAAGAAGATTCAGCTATGGTGTTTGTTTCAAATGAAGTTGGTGAGCATTCCATTACCACCCGTGACCTAAATGTGAATGA
GAACACCATCATACAATTTGAGATCAACGTTGGCTGTTCGACTGATAGCTCATCCGCGGATCCAGTGAGACTGGAATTTTCAAGGGACTT
CGGGGCGACCTGGCACCTTCTGCTGCCCCTCTGCTACCACAGCAGCAGCCACGTCAGCTCTTTATGCTCCACCGAGCACCACCCCAGCAG
CACCTACTACGCAGGAACCATGCAGGGCTGGAGGAGGGAGGTCGTGCACTTTGGGAAGCTGCACCTTTGTGGATCTGTCCGTTTCAGATG
GTACCAGGGATTTTACCCTGCCGGCTCTCAGCCAGTGACATGGGCCATTGATAATGTCTACATCGGTCCCCAGTGTGAGGAGATGTGTAA
TGGACAGGGGAGCTGTATCAATGGAACCAAATGTATATGTGACCCTGGCTACTCAGGTCCAACCTGTAAAATAAGCACCAAAAATCCTGA
TTTTCTCAAAGATGATTTCGAAGGTCAGCTAGAATCTGATAGATTCTTATTAATGAGTGGTGGGAAACCATCTCGAAAGTGTGGAATCCT
TTCTAGTGGAAACAACCTCTTTTTCAATGAAGATGGCTTGCGCATGTTGATGACACGAGACCTGGATTTATCACATGCTAGATTTGTGCA
GTTCTTCATGAGACTGGGATGTGGTAAAGGCGTTCCTGACCCCAGGAGTCAACCCGTGCTCCTACAGTATTCTCTCAACGGTGGCCTCTC
GTGGAGTCTTCTTCAGGAGTTCCTTTTCAGCAATTCCAGCAATGTGGGCAGGTACATTGCCCTGGAGATACCCTTGAAAGCCCGTTCTGG
TTCTACTCGCCTTCGCTGGTGGCAACCGTCTGAGAATGGGCACTTCTACAGCCCCTGGGTTATCGATCAGATTCTTATTGGAGGAAATAT
TTCTGGTAATACGGTCTTGGAAGATGATTTCACAACCCTTGATAGTAGGAAATGGCTGCTTCACCCAGGAGGCACCAAGATGCCCGTGTG
TGGCTCTACTGGTGATGCCCTGGTCTTCATTGAAAAGGCCAGCACCCGTTACGTGGTCAGCACAGACGTTGCCGTGAATGAGGATTCCTT
CCTACAGATAGACTTCGCTGCCTCCTGCTCAGTCACAGACTCTTGTTATGCGATTGAATTGGAATACTCAGTAGATCTTGGATTGTCATG
GCACCCATTGGTAAGGGACTGTCTGCCTACCAATGTGGAATGCAGTCGCTATCATCTGCAACGGATCCTGGTGTCAGACACTTTCAACAA
GTGGACTAGAATCACTCTGCCTCTCCCTCCTTATACCAGGACGGTGAACTTTGACATAATAAAATACTTGTATGATTTCTTGTGAAAACA
AGCTTCAAAGCCATATGGACACTGTGACAATGACTAAGCCAAGCTGTGTTCATCCAGCTACTTAGCTGGCCAAGGAGAGGAGTTCTTTGG
CTCTATTGGATTTGTCCAAACAGGTGCTGGCCCAGCATGGAATCTGATGAAAATATTCTGATTGGTCTGGGTGGATGTGAGCAGAAGACT
ATTTACCAGGGACCCTGGAGTATTTGGAAGCAACGTGTTAATTATAAACAGCAGGGTTTGAGCACAATCTGTTCTACTCTTAATGATGTT
ATCTTAACACTGAAATTGCCTGAAACCCATTTACTTAGGACTACATTTTGCTCTGTGAACTATCCCCTGCGCTTTGAACGTGCCAGCAGC
CCTTGTTTATATGCCCATTCTTTTCACTTCCTCTCCACAGGAGCCTCTGCAGTCGCTTGCCAAAGCAGATTTTCCTAAGGCCACTGTTTT

>73451_73451_3_RELN-ORC5_RELN_chr7_103175763_ENST00000428762_ORC5_chr7_103767340_ENST00000545943_length(amino acids)=2482AA_BP=2467
MNERAARRARGGGGGGGGMERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLHIAGNPTYYVPGQ
EYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQFGNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATAT
HRGQVIFKDALAQQLCEQGAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAVTFCEPYGPRELI
TTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKIRAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEAC
WALDNILIINSAHRQVVLEDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQWSEEFESQPTGWD
VLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVMGGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSL
VSVVINPELQTPATKFCLRQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRSWSLLHTECLPEI
CAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILGNMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEM
ASQTFPMFISESFGSSRLSSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKSVLSTCRAPDQPG
EGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFRWWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQS
LGFYLGNVQPYCGHDWTLCFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTWHLVQEECLPSMP
SCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQDEWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPE
AALPSTIMSDFENQNGWESDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGESASCNKPDSREEG
VLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWWQPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEK
PAFDYPMNQMSVWLMLANEGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVLLQYSHDAGMSWF
LVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLASSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDC
ISGVCFCDLGYTAAQGTCVSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDTRNIRLVQFYIQI
GSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQIISIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSS
QTGFQDKFDGSIDLQANWYRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSHSVQLQYSLNNGK
DWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPRTRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGR
CVCDRGFGGPYCVPVVPLPSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTMYVQFSLRFIAKS
TPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTNATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFD
FGPREDNWFFYPGGNIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWH
LLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLCGSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSC
INGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDLSHARFVQFFMRL
GCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEIPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTV
LEDDFTTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVR

--------------------------------------------------------------
>73451_73451_4_RELN-ORC5_RELN_chr7_103270387_ENST00000343529_ORC5_chr7_103767340_ENST00000545943_length(transcript)=3413nt_BP=2862nt
CTCGGCGGGGGCCCGCTCCCAGGCCCGCTCCCGAGCCCGTTCCGCTCCCGTCCGCCTTCTTCTCGCCTTCTCTCCGCGTGGCTCCTCCGT
CCCGGCGTCTCCAAAACTGAATGAGCGAGCGGCGCGTAGGGCGCGCGGCGGCGGCGGCGGCGGCGGCGGCATGGAGCGCAGTGGCTGGGC
CCGGCAGACTTTCCTCCTAGCGCTGTTGCTGGGGGCGACGCTGAGGGCGCGCGCGGCGGCTGGCTATTACCCCCGCTTTTCGCCCTTCTT
TTTCCTGTGCACCCACCACGGGGAGCTGGAAGGGGATGGGGAGCAGGGCGAGGTGCTCATTTCCCTGCATATTGCGGGCAACCCCACCTA
CTACGTTCCGGGACAAGAATACCATGTGACAATTTCAACAAGCACCTTTTTTGACGGCTTGCTGGTGACAGGACTATACACATCTACAAG
TGTTCAGGCATCACAGAGCATTGGAGGTTCCAGTGCTTTCGGATTTGGGATCATGTCTGACCACCAGTTTGGTAACCAGTTTATGTGCAG
TGTGGTAGCCTCTCACGTGAGTCACCTGCCCACAACCAACCTCAGTTTCATCTGGATTGCTCCACCTGCGGGCACAGGCTGTGTGAATTT
CATGGCTACAGCAACACACCGGGGCCAGGTTATTTTCAAAGATGCTTTAGCCCAGCAGTTGTGTGAACAAGGAGCTCCAACAGATGTCAC
TGTGCACCCACATCTAGCTGAAATACATAGTGACAGCATTATCCTGAGAGATGACTTTGACTCCTACCACCAACTGCAATTAAATCCAAA
TATATGGGTTGAATGTAACAACTGTGAGACTGGAGAACAGTGTGGCGCGATTATGCATGGCAATGCCGTCACCTTCTGTGAACCATATGG
CCCACGAGAACTGATTACCACAGGCCTTAATACAACAACAGCTTCTGTCCTCCAATTTTCCATTGGGTCAGGTTCATGTCGCTTTAGTTA
TTCAGACCCCAGCATCATCGTGTTATATGCCAAGAATAACTCTGCGGACTGGATTCAGCTAGAGAAAATTAGAGCCCCTTCCAATGTCAG
CACAATCATCCATATCCTCTACCTTCCTGAGGACGCCAAAGGGGAGAATGTCCAATTTCAGTGGAAGCAGGAAAATCTTCGTGTAGGTGA
AGTGTATGAAGCCTGCTGGGCCTTAGATAACATCTTGATCATCAATTCAGCTCACAGACAAGTCGTTTTAGAAGATAGTCTCGACCCAGT
GGACACAGGCAACTGGCTTTTCTTCCCAGGAGCTACAGTTAAGCATAGCTGTCAGTCAGATGGGAACTCCATTTATTTCCATGGAAATGA
AGGCAGCGAGTTCAATTTTGCCACCACCAGGGATGTAGATCTTTCCACAGAAGATATTCAAGAGCAATGGTCAGAAGAATTTGAGAGCCA
GCCTACAGGATGGGATGTCTTGGGAGCTGTCATTGGTACAGAATGTGGAACGATAGAATCAGGCTTATCAATGGTCTTCCTCAAAGATGG
AGAGAGGAAATTATGCACTCCATCCATGGACACTACCGGTTATGGGAACCTGAGGTTTTACTTTGTGATGGGAGGAATTTGTGACCCTGG
AAATTCTCATGAAAATGACATAATCCTGTATGCAAAAATTGAAGGAAGAAAAGAGCATATAACACTGGATACCCTTTCCTATTCCTCATA
TAAGGTTCCGTCTTTGGTTTCTGTGGTCATCAATCCTGAACTTCAGACTCCTGCTACCAAATTTTGTCTCAGGCAAAAGAACCATCAAGG
ACATAATAGGAATGTCTGGGCTGTAGACTTTTTCCATGTCTTGCCTGTTCTCCCTTCTACAATGTCTCACATGATACAGTTTTCCATCAA
TCTGGGATGTGGAACGCATCAGCCTGGTAACAGTGTCAGCTTGGAATTTTCTACCAACCATGGGCGCTCCTGGTCCCTCCTTCACACTGA
ATGCTTACCTGAGATCTGTGCTGGACCCCACCTCCCCCACAGCACTGTCTACTCCTCTGAAAACTACAGTGGGTGGAACCGAATAACAAT
TCCCCTTCCTAACGCAGCACTAACCCGGAACACCAGGATTCGCTGGAGACAAACAGGACCAATCCTTGGAAACATGTGGGCAATTGATAA
TGTTTATATTGGCCCGTCATGTCTCAAATTCTGTTCTGGCAGAGGACAGTGCACTAGACATGGTTGCAAGTGTGACCCTGGATTTTCTGG
CCCAGCTTGTGAGATGGCATCCCAGACATTCCCAATGTTTATTTCTGAAAGCTTTGGCAGTTCCAGGCTCTCCTCTTACCATAACTTTTA
CTCTATCCGTGGTGCTGAAGTCAGCTTTGGTTGTGGTGTCTTGGCCAGTGGTAAGGCCCTGGTTTTCAACAAAGATGGGCGGCGTCAGCT
AATTACATCTTTCCTTGACAGCTCACAATCCAGGTTTCTCCAGTTCACACTGAGACTGGGGAGCAAATCTGTTCTGAGCACGTGCAGAGC
CCCTGATCAGCCTGGTGAAGGAGTTTTGTTGCATTATTCTTATGATAATGGGATAACTTGGAAACTCCTGGAGCATTATTCATATCTCAG
CTATCATGAGCCCAGAATAATCTCCGTAGAACTACCAGGTGATGCAAAGCAGTTTGGAATTCAGTTCAGATGGTGGCAACCGTATCATTC
TTCCCAGAGAGAAGATGTATGGGCTATTGATGAGATTATCATGACATCTGTGCTTTTCAACAGCATTAGTCTTGACTTTACCAATCTTGT
GGAGGTCACTCAGTCTCTGGGATTCTACCTTGGAAATGTTCAGCCATACTGTGGCCACGACTGGACCCTTTGGACGGTGAACTTTGACAT
AATAAAATACTTGTATGATTTCTTGTGAAAACAAGCTTCAAAGCCATATGGACACTGTGACAATGACTAAGCCAAGCTGTGTTCATCCAG
CTACTTAGCTGGCCAAGGAGAGGAGTTCTTTGGCTCTATTGGATTTGTCCAAACAGGTGCTGGCCCAGCATGGAATCTGATGAAAATATT
CTGATTGGTCTGGGTGGATGTGAGCAGAAGACTATTTACCAGGGACCCTGGAGTATTTGGAAGCAACGTGTTAATTATAAACAGCAGGGT
TTGAGCACAATCTGTTCTACTCTTAATGATGTTATCTTAACACTGAAATTGCCTGAAACCCATTTACTTAGGACTACATTTTGCTCTGTG
AACTATCCCCTGCGCTTTGAACGTGCCAGCAGCCCTTGTTTATATGCCCATTCTTTTCACTTCCTCTCCACAGGAGCCTCTGCAGTCGCT

>73451_73451_4_RELN-ORC5_RELN_chr7_103270387_ENST00000343529_ORC5_chr7_103767340_ENST00000545943_length(amino acids)=933AA_BP=
MNERAARRARGGGGGGGGMERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLHIAGNPTYYVPGQ
EYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQFGNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATAT
HRGQVIFKDALAQQLCEQGAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAVTFCEPYGPRELI
TTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKIRAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEAC
WALDNILIINSAHRQVVLEDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQWSEEFESQPTGWD
VLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVMGGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSL
VSVVINPELQTPATKFCLRQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRSWSLLHTECLPEI
CAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILGNMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEM
ASQTFPMFISESFGSSRLSSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKSVLSTCRAPDQPG
EGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFRWWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQS

--------------------------------------------------------------
>73451_73451_5_RELN-ORC5_RELN_chr7_103270387_ENST00000424685_ORC5_chr7_103767340_ENST00000545943_length(transcript)=3413nt_BP=2862nt
CTCGGCGGGGGCCCGCTCCCAGGCCCGCTCCCGAGCCCGTTCCGCTCCCGTCCGCCTTCTTCTCGCCTTCTCTCCGCGTGGCTCCTCCGT
CCCGGCGTCTCCAAAACTGAATGAGCGAGCGGCGCGTAGGGCGCGCGGCGGCGGCGGCGGCGGCGGCGGCATGGAGCGCAGTGGCTGGGC
CCGGCAGACTTTCCTCCTAGCGCTGTTGCTGGGGGCGACGCTGAGGGCGCGCGCGGCGGCTGGCTATTACCCCCGCTTTTCGCCCTTCTT
TTTCCTGTGCACCCACCACGGGGAGCTGGAAGGGGATGGGGAGCAGGGCGAGGTGCTCATTTCCCTGCATATTGCGGGCAACCCCACCTA
CTACGTTCCGGGACAAGAATACCATGTGACAATTTCAACAAGCACCTTTTTTGACGGCTTGCTGGTGACAGGACTATACACATCTACAAG
TGTTCAGGCATCACAGAGCATTGGAGGTTCCAGTGCTTTCGGATTTGGGATCATGTCTGACCACCAGTTTGGTAACCAGTTTATGTGCAG
TGTGGTAGCCTCTCACGTGAGTCACCTGCCCACAACCAACCTCAGTTTCATCTGGATTGCTCCACCTGCGGGCACAGGCTGTGTGAATTT
CATGGCTACAGCAACACACCGGGGCCAGGTTATTTTCAAAGATGCTTTAGCCCAGCAGTTGTGTGAACAAGGAGCTCCAACAGATGTCAC
TGTGCACCCACATCTAGCTGAAATACATAGTGACAGCATTATCCTGAGAGATGACTTTGACTCCTACCACCAACTGCAATTAAATCCAAA
TATATGGGTTGAATGTAACAACTGTGAGACTGGAGAACAGTGTGGCGCGATTATGCATGGCAATGCCGTCACCTTCTGTGAACCATATGG
CCCACGAGAACTGATTACCACAGGCCTTAATACAACAACAGCTTCTGTCCTCCAATTTTCCATTGGGTCAGGTTCATGTCGCTTTAGTTA
TTCAGACCCCAGCATCATCGTGTTATATGCCAAGAATAACTCTGCGGACTGGATTCAGCTAGAGAAAATTAGAGCCCCTTCCAATGTCAG
CACAATCATCCATATCCTCTACCTTCCTGAGGACGCCAAAGGGGAGAATGTCCAATTTCAGTGGAAGCAGGAAAATCTTCGTGTAGGTGA
AGTGTATGAAGCCTGCTGGGCCTTAGATAACATCTTGATCATCAATTCAGCTCACAGACAAGTCGTTTTAGAAGATAGTCTCGACCCAGT
GGACACAGGCAACTGGCTTTTCTTCCCAGGAGCTACAGTTAAGCATAGCTGTCAGTCAGATGGGAACTCCATTTATTTCCATGGAAATGA
AGGCAGCGAGTTCAATTTTGCCACCACCAGGGATGTAGATCTTTCCACAGAAGATATTCAAGAGCAATGGTCAGAAGAATTTGAGAGCCA
GCCTACAGGATGGGATGTCTTGGGAGCTGTCATTGGTACAGAATGTGGAACGATAGAATCAGGCTTATCAATGGTCTTCCTCAAAGATGG
AGAGAGGAAATTATGCACTCCATCCATGGACACTACCGGTTATGGGAACCTGAGGTTTTACTTTGTGATGGGAGGAATTTGTGACCCTGG
AAATTCTCATGAAAATGACATAATCCTGTATGCAAAAATTGAAGGAAGAAAAGAGCATATAACACTGGATACCCTTTCCTATTCCTCATA
TAAGGTTCCGTCTTTGGTTTCTGTGGTCATCAATCCTGAACTTCAGACTCCTGCTACCAAATTTTGTCTCAGGCAAAAGAACCATCAAGG
ACATAATAGGAATGTCTGGGCTGTAGACTTTTTCCATGTCTTGCCTGTTCTCCCTTCTACAATGTCTCACATGATACAGTTTTCCATCAA
TCTGGGATGTGGAACGCATCAGCCTGGTAACAGTGTCAGCTTGGAATTTTCTACCAACCATGGGCGCTCCTGGTCCCTCCTTCACACTGA
ATGCTTACCTGAGATCTGTGCTGGACCCCACCTCCCCCACAGCACTGTCTACTCCTCTGAAAACTACAGTGGGTGGAACCGAATAACAAT
TCCCCTTCCTAACGCAGCACTAACCCGGAACACCAGGATTCGCTGGAGACAAACAGGACCAATCCTTGGAAACATGTGGGCAATTGATAA
TGTTTATATTGGCCCGTCATGTCTCAAATTCTGTTCTGGCAGAGGACAGTGCACTAGACATGGTTGCAAGTGTGACCCTGGATTTTCTGG
CCCAGCTTGTGAGATGGCATCCCAGACATTCCCAATGTTTATTTCTGAAAGCTTTGGCAGTTCCAGGCTCTCCTCTTACCATAACTTTTA
CTCTATCCGTGGTGCTGAAGTCAGCTTTGGTTGTGGTGTCTTGGCCAGTGGTAAGGCCCTGGTTTTCAACAAAGATGGGCGGCGTCAGCT
AATTACATCTTTCCTTGACAGCTCACAATCCAGGTTTCTCCAGTTCACACTGAGACTGGGGAGCAAATCTGTTCTGAGCACGTGCAGAGC
CCCTGATCAGCCTGGTGAAGGAGTTTTGTTGCATTATTCTTATGATAATGGGATAACTTGGAAACTCCTGGAGCATTATTCATATCTCAG
CTATCATGAGCCCAGAATAATCTCCGTAGAACTACCAGGTGATGCAAAGCAGTTTGGAATTCAGTTCAGATGGTGGCAACCGTATCATTC
TTCCCAGAGAGAAGATGTATGGGCTATTGATGAGATTATCATGACATCTGTGCTTTTCAACAGCATTAGTCTTGACTTTACCAATCTTGT
GGAGGTCACTCAGTCTCTGGGATTCTACCTTGGAAATGTTCAGCCATACTGTGGCCACGACTGGACCCTTTGGACGGTGAACTTTGACAT
AATAAAATACTTGTATGATTTCTTGTGAAAACAAGCTTCAAAGCCATATGGACACTGTGACAATGACTAAGCCAAGCTGTGTTCATCCAG
CTACTTAGCTGGCCAAGGAGAGGAGTTCTTTGGCTCTATTGGATTTGTCCAAACAGGTGCTGGCCCAGCATGGAATCTGATGAAAATATT
CTGATTGGTCTGGGTGGATGTGAGCAGAAGACTATTTACCAGGGACCCTGGAGTATTTGGAAGCAACGTGTTAATTATAAACAGCAGGGT
TTGAGCACAATCTGTTCTACTCTTAATGATGTTATCTTAACACTGAAATTGCCTGAAACCCATTTACTTAGGACTACATTTTGCTCTGTG
AACTATCCCCTGCGCTTTGAACGTGCCAGCAGCCCTTGTTTATATGCCCATTCTTTTCACTTCCTCTCCACAGGAGCCTCTGCAGTCGCT

>73451_73451_5_RELN-ORC5_RELN_chr7_103270387_ENST00000424685_ORC5_chr7_103767340_ENST00000545943_length(amino acids)=933AA_BP=
MNERAARRARGGGGGGGGMERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLHIAGNPTYYVPGQ
EYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQFGNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATAT
HRGQVIFKDALAQQLCEQGAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAVTFCEPYGPRELI
TTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKIRAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEAC
WALDNILIINSAHRQVVLEDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQWSEEFESQPTGWD
VLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVMGGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSL
VSVVINPELQTPATKFCLRQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRSWSLLHTECLPEI
CAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILGNMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEM
ASQTFPMFISESFGSSRLSSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKSVLSTCRAPDQPG
EGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFRWWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQS

--------------------------------------------------------------
>73451_73451_6_RELN-ORC5_RELN_chr7_103270387_ENST00000428762_ORC5_chr7_103767340_ENST00000545943_length(transcript)=3413nt_BP=2862nt
CTCGGCGGGGGCCCGCTCCCAGGCCCGCTCCCGAGCCCGTTCCGCTCCCGTCCGCCTTCTTCTCGCCTTCTCTCCGCGTGGCTCCTCCGT
CCCGGCGTCTCCAAAACTGAATGAGCGAGCGGCGCGTAGGGCGCGCGGCGGCGGCGGCGGCGGCGGCGGCATGGAGCGCAGTGGCTGGGC
CCGGCAGACTTTCCTCCTAGCGCTGTTGCTGGGGGCGACGCTGAGGGCGCGCGCGGCGGCTGGCTATTACCCCCGCTTTTCGCCCTTCTT
TTTCCTGTGCACCCACCACGGGGAGCTGGAAGGGGATGGGGAGCAGGGCGAGGTGCTCATTTCCCTGCATATTGCGGGCAACCCCACCTA
CTACGTTCCGGGACAAGAATACCATGTGACAATTTCAACAAGCACCTTTTTTGACGGCTTGCTGGTGACAGGACTATACACATCTACAAG
TGTTCAGGCATCACAGAGCATTGGAGGTTCCAGTGCTTTCGGATTTGGGATCATGTCTGACCACCAGTTTGGTAACCAGTTTATGTGCAG
TGTGGTAGCCTCTCACGTGAGTCACCTGCCCACAACCAACCTCAGTTTCATCTGGATTGCTCCACCTGCGGGCACAGGCTGTGTGAATTT
CATGGCTACAGCAACACACCGGGGCCAGGTTATTTTCAAAGATGCTTTAGCCCAGCAGTTGTGTGAACAAGGAGCTCCAACAGATGTCAC
TGTGCACCCACATCTAGCTGAAATACATAGTGACAGCATTATCCTGAGAGATGACTTTGACTCCTACCACCAACTGCAATTAAATCCAAA
TATATGGGTTGAATGTAACAACTGTGAGACTGGAGAACAGTGTGGCGCGATTATGCATGGCAATGCCGTCACCTTCTGTGAACCATATGG
CCCACGAGAACTGATTACCACAGGCCTTAATACAACAACAGCTTCTGTCCTCCAATTTTCCATTGGGTCAGGTTCATGTCGCTTTAGTTA
TTCAGACCCCAGCATCATCGTGTTATATGCCAAGAATAACTCTGCGGACTGGATTCAGCTAGAGAAAATTAGAGCCCCTTCCAATGTCAG
CACAATCATCCATATCCTCTACCTTCCTGAGGACGCCAAAGGGGAGAATGTCCAATTTCAGTGGAAGCAGGAAAATCTTCGTGTAGGTGA
AGTGTATGAAGCCTGCTGGGCCTTAGATAACATCTTGATCATCAATTCAGCTCACAGACAAGTCGTTTTAGAAGATAGTCTCGACCCAGT
GGACACAGGCAACTGGCTTTTCTTCCCAGGAGCTACAGTTAAGCATAGCTGTCAGTCAGATGGGAACTCCATTTATTTCCATGGAAATGA
AGGCAGCGAGTTCAATTTTGCCACCACCAGGGATGTAGATCTTTCCACAGAAGATATTCAAGAGCAATGGTCAGAAGAATTTGAGAGCCA
GCCTACAGGATGGGATGTCTTGGGAGCTGTCATTGGTACAGAATGTGGAACGATAGAATCAGGCTTATCAATGGTCTTCCTCAAAGATGG
AGAGAGGAAATTATGCACTCCATCCATGGACACTACCGGTTATGGGAACCTGAGGTTTTACTTTGTGATGGGAGGAATTTGTGACCCTGG
AAATTCTCATGAAAATGACATAATCCTGTATGCAAAAATTGAAGGAAGAAAAGAGCATATAACACTGGATACCCTTTCCTATTCCTCATA
TAAGGTTCCGTCTTTGGTTTCTGTGGTCATCAATCCTGAACTTCAGACTCCTGCTACCAAATTTTGTCTCAGGCAAAAGAACCATCAAGG
ACATAATAGGAATGTCTGGGCTGTAGACTTTTTCCATGTCTTGCCTGTTCTCCCTTCTACAATGTCTCACATGATACAGTTTTCCATCAA
TCTGGGATGTGGAACGCATCAGCCTGGTAACAGTGTCAGCTTGGAATTTTCTACCAACCATGGGCGCTCCTGGTCCCTCCTTCACACTGA
ATGCTTACCTGAGATCTGTGCTGGACCCCACCTCCCCCACAGCACTGTCTACTCCTCTGAAAACTACAGTGGGTGGAACCGAATAACAAT
TCCCCTTCCTAACGCAGCACTAACCCGGAACACCAGGATTCGCTGGAGACAAACAGGACCAATCCTTGGAAACATGTGGGCAATTGATAA
TGTTTATATTGGCCCGTCATGTCTCAAATTCTGTTCTGGCAGAGGACAGTGCACTAGACATGGTTGCAAGTGTGACCCTGGATTTTCTGG
CCCAGCTTGTGAGATGGCATCCCAGACATTCCCAATGTTTATTTCTGAAAGCTTTGGCAGTTCCAGGCTCTCCTCTTACCATAACTTTTA
CTCTATCCGTGGTGCTGAAGTCAGCTTTGGTTGTGGTGTCTTGGCCAGTGGTAAGGCCCTGGTTTTCAACAAAGATGGGCGGCGTCAGCT
AATTACATCTTTCCTTGACAGCTCACAATCCAGGTTTCTCCAGTTCACACTGAGACTGGGGAGCAAATCTGTTCTGAGCACGTGCAGAGC
CCCTGATCAGCCTGGTGAAGGAGTTTTGTTGCATTATTCTTATGATAATGGGATAACTTGGAAACTCCTGGAGCATTATTCATATCTCAG
CTATCATGAGCCCAGAATAATCTCCGTAGAACTACCAGGTGATGCAAAGCAGTTTGGAATTCAGTTCAGATGGTGGCAACCGTATCATTC
TTCCCAGAGAGAAGATGTATGGGCTATTGATGAGATTATCATGACATCTGTGCTTTTCAACAGCATTAGTCTTGACTTTACCAATCTTGT
GGAGGTCACTCAGTCTCTGGGATTCTACCTTGGAAATGTTCAGCCATACTGTGGCCACGACTGGACCCTTTGGACGGTGAACTTTGACAT
AATAAAATACTTGTATGATTTCTTGTGAAAACAAGCTTCAAAGCCATATGGACACTGTGACAATGACTAAGCCAAGCTGTGTTCATCCAG
CTACTTAGCTGGCCAAGGAGAGGAGTTCTTTGGCTCTATTGGATTTGTCCAAACAGGTGCTGGCCCAGCATGGAATCTGATGAAAATATT
CTGATTGGTCTGGGTGGATGTGAGCAGAAGACTATTTACCAGGGACCCTGGAGTATTTGGAAGCAACGTGTTAATTATAAACAGCAGGGT
TTGAGCACAATCTGTTCTACTCTTAATGATGTTATCTTAACACTGAAATTGCCTGAAACCCATTTACTTAGGACTACATTTTGCTCTGTG
AACTATCCCCTGCGCTTTGAACGTGCCAGCAGCCCTTGTTTATATGCCCATTCTTTTCACTTCCTCTCCACAGGAGCCTCTGCAGTCGCT

>73451_73451_6_RELN-ORC5_RELN_chr7_103270387_ENST00000428762_ORC5_chr7_103767340_ENST00000545943_length(amino acids)=933AA_BP=
MNERAARRARGGGGGGGGMERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLHIAGNPTYYVPGQ
EYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQFGNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATAT
HRGQVIFKDALAQQLCEQGAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAVTFCEPYGPRELI
TTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKIRAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEAC
WALDNILIINSAHRQVVLEDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQWSEEFESQPTGWD
VLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVMGGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSL
VSVVINPELQTPATKFCLRQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRSWSLLHTECLPEI
CAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILGNMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEM
ASQTFPMFISESFGSSRLSSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKSVLSTCRAPDQPG
EGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFRWWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQS

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Fusion Gene PPI Analysis for RELN-ORC5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RELN-ORC5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RELN-ORC5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource