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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RFTN1-DAZL (FusionGDB2 ID:73661)

Fusion Gene Summary for RFTN1-DAZL

check button Fusion gene summary
Fusion gene informationFusion gene name: RFTN1-DAZL
Fusion gene ID: 73661
HgeneTgene
Gene symbol

RFTN1

DAZL

Gene ID

23180

1618

Gene nameraftlin, lipid raft linker 1deleted in azoospermia like
SynonymsMIG2|PIB10|PIG9|RAFTLINDAZH|DAZL1|DAZLA|SPGYLA
Cytomap

3p24.3

3p24.3

Type of geneprotein-codingprotein-coding
Descriptionraftlincell migration-inducing gene 2 proteinproliferation-inducing protein 10proliferation-inducing protein 9raft-linking proteindeleted in azoospermia-likeDAZ homologDAZ-like autosomalSPGY-like-autosomaldeleted in azoospermia-like 1germline specific RNA binding proteinspermatogenesis gene on the Y-like autosomaltestis secretory sperm-binding protein Li 204a
Modification date2020031320200313
UniProtAcc.

Q92904

Ensembl transtripts involved in fusion geneENST00000334133, ENST00000432519, 
ENST00000483671, 		ENST00000399444, 
ENST00000250863, 
Fusion gene scores* DoF score7 X 8 X 6=3365 X 4 X 6=120
# samples 108
** MAII scorelog2(10/336*10)=-1.74846123300404
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/120*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RFTN1 [Title/Abstract] AND DAZL [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRFTN1(16450882)-DAZL(16636090), # samples:3
RFTN1(16450882)-DAZL(16640105), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneDAZL

GO:0045948

positive regulation of translational initiation

16001084


check buttonFusion gene breakpoints across RFTN1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DAZL (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AO-A128-01ARFTN1chr3

16535232

-DAZLchr3

16640105

-
ChimerDB4BRCATCGA-BH-A0B9-01ARFTN1chr3

16368280

-DAZLchr3

16646818

-
ChimerDB4BRCATCGA-BH-A0B9-01ARFTN1chr3

16399439

-DAZLchr3

16640105

-
ChimerDB4BRCATCGA-BH-A0BZ-01ARFTN1chr3

16450882

-DAZLchr3

16636090

-
ChimerDB4LUADTCGA-55-6972-01ARFTN1chr3

16450882

-DAZLchr3

16640105

-


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Fusion Gene ORF analysis for RFTN1-DAZL

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000334133ENST00000399444RFTN1chr3

16368280

-DAZLchr3

16646818

-
5CDS-5UTRENST00000432519ENST00000399444RFTN1chr3

16368280

-DAZLchr3

16646818

-
5CDS-intronENST00000334133ENST00000250863RFTN1chr3

16368280

-DAZLchr3

16646818

-
5CDS-intronENST00000432519ENST00000250863RFTN1chr3

16368280

-DAZLchr3

16646818

-
5UTR-3CDSENST00000483671ENST00000250863RFTN1chr3

16399439

-DAZLchr3

16640105

-
5UTR-3CDSENST00000483671ENST00000399444RFTN1chr3

16399439

-DAZLchr3

16640105

-
5UTR-5UTRENST00000483671ENST00000399444RFTN1chr3

16368280

-DAZLchr3

16646818

-
5UTR-intronENST00000483671ENST00000250863RFTN1chr3

16368280

-DAZLchr3

16646818

-
Frame-shiftENST00000334133ENST00000250863RFTN1chr3

16399439

-DAZLchr3

16640105

-
Frame-shiftENST00000334133ENST00000250863RFTN1chr3

16450882

-DAZLchr3

16636090

-
Frame-shiftENST00000334133ENST00000250863RFTN1chr3

16450882

-DAZLchr3

16640105

-
Frame-shiftENST00000334133ENST00000399444RFTN1chr3

16399439

-DAZLchr3

16640105

-
Frame-shiftENST00000334133ENST00000399444RFTN1chr3

16450882

-DAZLchr3

16636090

-
Frame-shiftENST00000334133ENST00000399444RFTN1chr3

16450882

-DAZLchr3

16640105

-
In-frameENST00000334133ENST00000250863RFTN1chr3

16535232

-DAZLchr3

16640105

-
In-frameENST00000334133ENST00000399444RFTN1chr3

16535232

-DAZLchr3

16640105

-
In-frameENST00000432519ENST00000250863RFTN1chr3

16399439

-DAZLchr3

16640105

-
In-frameENST00000432519ENST00000250863RFTN1chr3

16450882

-DAZLchr3

16636090

-
In-frameENST00000432519ENST00000250863RFTN1chr3

16450882

-DAZLchr3

16640105

-
In-frameENST00000432519ENST00000399444RFTN1chr3

16399439

-DAZLchr3

16640105

-
In-frameENST00000432519ENST00000399444RFTN1chr3

16450882

-DAZLchr3

16636090

-
In-frameENST00000432519ENST00000399444RFTN1chr3

16450882

-DAZLchr3

16640105

-
intron-3CDSENST00000432519ENST00000250863RFTN1chr3

16535232

-DAZLchr3

16640105

-
intron-3CDSENST00000432519ENST00000399444RFTN1chr3

16535232

-DAZLchr3

16640105

-
intron-3CDSENST00000483671ENST00000250863RFTN1chr3

16535232

-DAZLchr3

16640105

-
intron-3CDSENST00000483671ENST00000250863RFTN1chr3

16450882

-DAZLchr3

16636090

-
intron-3CDSENST00000483671ENST00000250863RFTN1chr3

16450882

-DAZLchr3

16640105

-
intron-3CDSENST00000483671ENST00000399444RFTN1chr3

16535232

-DAZLchr3

16640105

-
intron-3CDSENST00000483671ENST00000399444RFTN1chr3

16450882

-DAZLchr3

16636090

-
intron-3CDSENST00000483671ENST00000399444RFTN1chr3

16450882

-DAZLchr3

16640105

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000334133RFTN1chr316535232-ENST00000250863DAZLchr316640105-31714184151302295
ENST00000334133RFTN1chr316535232-ENST00000399444DAZLchr316640105-31714184151302295
ENST00000432519RFTN1chr316450882-ENST00000250863DAZLchr316636090-260241638733231
ENST00000432519RFTN1chr316450882-ENST00000399444DAZLchr316636090-260241638733231
ENST00000432519RFTN1chr316450882-ENST00000250863DAZLchr316640105-3169416381300420
ENST00000432519RFTN1chr316450882-ENST00000399444DAZLchr316640105-3169416381300420
ENST00000432519RFTN1chr316399439-ENST00000250863DAZLchr316640105-38741121382005655
ENST00000432519RFTN1chr316399439-ENST00000399444DAZLchr316640105-38741121382005655

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000334133ENST00000250863RFTN1chr316535232-DAZLchr316640105-0.0002980290.9997019
ENST00000334133ENST00000399444RFTN1chr316535232-DAZLchr316640105-0.0002980290.9997019
ENST00000432519ENST00000250863RFTN1chr316450882-DAZLchr316636090-0.0009883750.99901164
ENST00000432519ENST00000399444RFTN1chr316450882-DAZLchr316636090-0.0009883750.99901164
ENST00000432519ENST00000250863RFTN1chr316450882-DAZLchr316640105-0.0001325260.99986744
ENST00000432519ENST00000399444RFTN1chr316450882-DAZLchr316640105-0.0001325260.99986744
ENST00000432519ENST00000250863RFTN1chr316399439-DAZLchr316640105-0.0002048220.99979514
ENST00000432519ENST00000399444RFTN1chr316399439-DAZLchr316640105-0.0002048220.99979514

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Fusion Genomic Features for RFTN1-DAZL


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RFTN1-DAZL


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:16450882/chr3:16636090)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DAZL

Q92904

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDAZLchr3:16399439chr3:16640105ENST00000250863011167_19021316.0DomainDAZ
TgeneDAZLchr3:16399439chr3:16640105ENST0000025086301140_11521316.0DomainRRM
TgeneDAZLchr3:16399439chr3:16640105ENST00000399444011167_1901296.0DomainDAZ
TgeneDAZLchr3:16399439chr3:16640105ENST0000039944401140_1151296.0DomainRRM
TgeneDAZLchr3:16450882chr3:16640105ENST00000250863011167_19021316.0DomainDAZ
TgeneDAZLchr3:16450882chr3:16640105ENST0000025086301140_11521316.0DomainRRM
TgeneDAZLchr3:16450882chr3:16640105ENST00000399444011167_1901296.0DomainDAZ
TgeneDAZLchr3:16450882chr3:16640105ENST0000039944401140_1151296.0DomainRRM
TgeneDAZLchr3:16535232chr3:16640105ENST00000250863011167_19021316.0DomainDAZ
TgeneDAZLchr3:16535232chr3:16640105ENST0000025086301140_11521316.0DomainRRM
TgeneDAZLchr3:16535232chr3:16640105ENST00000399444011167_1901296.0DomainDAZ
TgeneDAZLchr3:16535232chr3:16640105ENST0000039944401140_1151296.0DomainRRM
TgeneDAZLchr3:16399439chr3:16640105ENST0000025086301180_13221316.0RegionHomodimerization
TgeneDAZLchr3:16399439chr3:16640105ENST0000039944401180_1321296.0RegionHomodimerization
TgeneDAZLchr3:16450882chr3:16640105ENST0000025086301180_13221316.0RegionHomodimerization
TgeneDAZLchr3:16450882chr3:16640105ENST0000039944401180_1321296.0RegionHomodimerization
TgeneDAZLchr3:16535232chr3:16640105ENST0000025086301180_13221316.0RegionHomodimerization
TgeneDAZLchr3:16535232chr3:16640105ENST0000039944401180_1321296.0RegionHomodimerization

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDAZLchr3:16450882chr3:16636090ENST00000250863611167_190210316.0DomainDAZ
TgeneDAZLchr3:16450882chr3:16636090ENST0000025086361140_115210316.0DomainRRM
TgeneDAZLchr3:16450882chr3:16636090ENST00000399444611167_190190296.0DomainDAZ
TgeneDAZLchr3:16450882chr3:16636090ENST0000039944461140_115190296.0DomainRRM
TgeneDAZLchr3:16450882chr3:16636090ENST0000025086361180_132210316.0RegionHomodimerization
TgeneDAZLchr3:16450882chr3:16636090ENST0000039944461180_132190296.0RegionHomodimerization


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Fusion Gene Sequence for RFTN1-DAZL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>73661_73661_1_RFTN1-DAZL_RFTN1_chr3_16399439_ENST00000432519_DAZL_chr3_16640105_ENST00000250863_length(transcript)=3874nt_BP=1121nt
CTCGTACAGTCCTTCATCTTCATGGCAGAAAGGCTGTTCTGCCCCTGCGCCCTCCCTGGCCTCTCTGGGGATCCCTGCAGCTGATGTATT
GTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCCGCCCAGC
TCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGC
ACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTAGATTGCT
GTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGATCCAGGAGGCTGCAAGCCAGGGCCTGAAATTCG
TTGGTGTTATACCTCAGTACCATTCCTCTGTGAACTCGGCAGGCAGCAGTGCTCCGGTGTCTACTGCCAACAGCACCGAGGATGCCAGAG
ATGCAAAAAACGCACGTGGGGATCACGCGTCACTGGAGAATGAGAAACCGGGGACTGGGGATGTGTGCAGTGCTCCGGCTGGGAGAAACC
AAAGCCCAGAGCCCAGCTCAGGCCCCAGAGGGGAGGTGCCCCTCGCCAAGCAGCCCAGCTCACCCTCCGGAGAGGGAGATGGTGGAGAAC
TTTCACCACAGGGGGTGAGCAAGACACTGGATGGACCGGAGAGCAACCCCTTGGAGGTGCATGAAGAGCCACTCTCAGGGAAAATGGAGA
TCTTCACCCTTTTCAACAAACCGAAGAGCCATCAGAAGTGCCGGCAATACTACCCTGTCACCATTCCTCTCCATGTCTCCAAGAATGGCC
AGACAGTGAGCGGTTTGGACGCCAACTGGTTAGAGCACATGAGCGACCACTTCCGGAAAGGAGGCATGCTGGTGAACGCAGTCTTCTACC
TTGGAATAGTGAATGATTCCTTACATGGCTTGACAGATGGAGTATTCATCTTTGAAGCTGTTTCCACAGAAGATAGCAAAACCATACAGG
GCTATGATGCTATTGTGGTTGAACAATGGACAGTCCTGGAATCTACTGCAAATCCTGAAACTCCAAACTCAACCATCTCCAGAGAGGCCA
GCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGTTTTTGTTGGAGGAATTG
ATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAATCACTGATCGAACTGGTG
TGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAATTTCCATGGTAAAAAGC
TGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAATCATCCTCCTCCACCAC
AGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAACTCAGTATGTTCAGGCAT
ATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCCACCACAGTGGCCTGTTG
GGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAGCTGAAGTTGTGCCAA
ATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATACAAACGGTGGTATCTT
GTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGCATCACTTTAGAAGAA
GTCGGGCAATGCTTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATATTAAGCTAAAAGGTTTCC
ACTATTATAGAAATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCTAGTTTTATCTTAAACTG
TTCTTCATTAGATGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGACTGAAAGAAACTAAGATT
TATCTGCAAGGATTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTTTTAAAAACCTATTTTGA
AAGGTCAGAATTTTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATTTACAGTATTGAGCTTTG
CATTTATGATTTCTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCAATATATAGTTAGCTTTA
TTGAAGTCTTCTTATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTATTCAAAATATTTTATCTT
TTAGCTAGAATCCACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAATTTTTTAAAGAATCCAA
GACAAACTAAACTTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTTCTTTGAAATGCTAAACT
TGGCTGTATGTCAAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTAATCAGAGTATCTGAAGG
GAATTGTTTTTATAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTTGTAAAGTAAAATATGTC
CAGAAGAGTCAAAGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAATGTGCTAGAGTTAAAAGT
TAGCATTGTTTCTAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTTGCTATACCACAGTCTTT
CGTTTCCAGCCTTTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGCTGTATGAGCAGAGCAGT
TCAAGGGCCAAACCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCATTTGATCTGCCATGGAC
ATGAGTTTAAAGCGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATGTAGTTACTGTGAGCCAT
ATTACTAGTGCCCCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAACTTTAGAATTCCCAAGAG
GGCTTTATTACACCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGTGCTATAACATTCTGACA
CATATCATTCTGTGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTATTCCAATATGACCTTAAG
GAAAAGTAAGGGAATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAGTCCTGAACCTTTCAAAA
TGGAAAATTAATTCTAAACTTAGAAATATGCTTCTGCCTATTGCTGATACTGTCTTTGCATACATGAATAAAAATAAAGTTTTTTTCTTC

>73661_73661_1_RFTN1-DAZL_RFTN1_chr3_16399439_ENST00000432519_DAZL_chr3_16640105_ENST00000250863_length(amino acids)=655AA_BP=359
MPLRPPWPLWGSLQLMYCDGAVDLDAAAELPGSSAVRLASLRDLPAQLLELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDR
SQKTDLHNEGYILELDCCSSLDHPTDQKLIPEFIKKIQEAASQGLKFVGVIPQYHSSVNSAGSSAPVSTANSTEDARDAKNARGDHASLE
NEKPGTGDVCSAPAGRNQSPEPSSGPRGEVPLAKQPSSPSGEGDGGELSPQGVSKTLDGPESNPLEVHEEPLSGKMEIFTLFNKPKSHQK
CRQYYPVTIPLHVSKNGQTVSGLDANWLEHMSDHFRKGGMLVNAVFYLGIVNDSLHGLTDGVFIFEAVSTEDSKTIQGYDAIVVEQWTVL
ESTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFND
VDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSV

--------------------------------------------------------------
>73661_73661_2_RFTN1-DAZL_RFTN1_chr3_16399439_ENST00000432519_DAZL_chr3_16640105_ENST00000399444_length(transcript)=3874nt_BP=1121nt
CTCGTACAGTCCTTCATCTTCATGGCAGAAAGGCTGTTCTGCCCCTGCGCCCTCCCTGGCCTCTCTGGGGATCCCTGCAGCTGATGTATT
GTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCCGCCCAGC
TCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGC
ACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTAGATTGCT
GTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGATCCAGGAGGCTGCAAGCCAGGGCCTGAAATTCG
TTGGTGTTATACCTCAGTACCATTCCTCTGTGAACTCGGCAGGCAGCAGTGCTCCGGTGTCTACTGCCAACAGCACCGAGGATGCCAGAG
ATGCAAAAAACGCACGTGGGGATCACGCGTCACTGGAGAATGAGAAACCGGGGACTGGGGATGTGTGCAGTGCTCCGGCTGGGAGAAACC
AAAGCCCAGAGCCCAGCTCAGGCCCCAGAGGGGAGGTGCCCCTCGCCAAGCAGCCCAGCTCACCCTCCGGAGAGGGAGATGGTGGAGAAC
TTTCACCACAGGGGGTGAGCAAGACACTGGATGGACCGGAGAGCAACCCCTTGGAGGTGCATGAAGAGCCACTCTCAGGGAAAATGGAGA
TCTTCACCCTTTTCAACAAACCGAAGAGCCATCAGAAGTGCCGGCAATACTACCCTGTCACCATTCCTCTCCATGTCTCCAAGAATGGCC
AGACAGTGAGCGGTTTGGACGCCAACTGGTTAGAGCACATGAGCGACCACTTCCGGAAAGGAGGCATGCTGGTGAACGCAGTCTTCTACC
TTGGAATAGTGAATGATTCCTTACATGGCTTGACAGATGGAGTATTCATCTTTGAAGCTGTTTCCACAGAAGATAGCAAAACCATACAGG
GCTATGATGCTATTGTGGTTGAACAATGGACAGTCCTGGAATCTACTGCAAATCCTGAAACTCCAAACTCAACCATCTCCAGAGAGGCCA
GCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGTTTTTGTTGGAGGAATTG
ATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAATCACTGATCGAACTGGTG
TGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAATTTCCATGGTAAAAAGC
TGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAATCATCCTCCTCCACCAC
AGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAACTCAGTATGTTCAGGCAT
ATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCCACCACAGTGGCCTGTTG
GGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAGCTGAAGTTGTGCCAA
ATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATACAAACGGTGGTATCTT
GTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGCATCACTTTAGAAGAA
GTCGGGCAATGCTTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATATTAAGCTAAAAGGTTTCC
ACTATTATAGAAATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCTAGTTTTATCTTAAACTG
TTCTTCATTAGATGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGACTGAAAGAAACTAAGATT
TATCTGCAAGGATTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTTTTAAAAACCTATTTTGA
AAGGTCAGAATTTTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATTTACAGTATTGAGCTTTG
CATTTATGATTTCTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCAATATATAGTTAGCTTTA
TTGAAGTCTTCTTATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTATTCAAAATATTTTATCTT
TTAGCTAGAATCCACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAATTTTTTAAAGAATCCAA
GACAAACTAAACTTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTTCTTTGAAATGCTAAACT
TGGCTGTATGTCAAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTAATCAGAGTATCTGAAGG
GAATTGTTTTTATAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTTGTAAAGTAAAATATGTC
CAGAAGAGTCAAAGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAATGTGCTAGAGTTAAAAGT
TAGCATTGTTTCTAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTTGCTATACCACAGTCTTT
CGTTTCCAGCCTTTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGCTGTATGAGCAGAGCAGT
TCAAGGGCCAAACCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCATTTGATCTGCCATGGAC
ATGAGTTTAAAGCGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATGTAGTTACTGTGAGCCAT
ATTACTAGTGCCCCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAACTTTAGAATTCCCAAGAG
GGCTTTATTACACCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGTGCTATAACATTCTGACA
CATATCATTCTGTGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTATTCCAATATGACCTTAAG
GAAAAGTAAGGGAATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAGTCCTGAACCTTTCAAAA
TGGAAAATTAATTCTAAACTTAGAAATATGCTTCTGCCTATTGCTGATACTGTCTTTGCATACATGAATAAAAATAAAGTTTTTTTCTTC

>73661_73661_2_RFTN1-DAZL_RFTN1_chr3_16399439_ENST00000432519_DAZL_chr3_16640105_ENST00000399444_length(amino acids)=655AA_BP=359
MPLRPPWPLWGSLQLMYCDGAVDLDAAAELPGSSAVRLASLRDLPAQLLELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDR
SQKTDLHNEGYILELDCCSSLDHPTDQKLIPEFIKKIQEAASQGLKFVGVIPQYHSSVNSAGSSAPVSTANSTEDARDAKNARGDHASLE
NEKPGTGDVCSAPAGRNQSPEPSSGPRGEVPLAKQPSSPSGEGDGGELSPQGVSKTLDGPESNPLEVHEEPLSGKMEIFTLFNKPKSHQK
CRQYYPVTIPLHVSKNGQTVSGLDANWLEHMSDHFRKGGMLVNAVFYLGIVNDSLHGLTDGVFIFEAVSTEDSKTIQGYDAIVVEQWTVL
ESTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFND
VDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSV

--------------------------------------------------------------
>73661_73661_3_RFTN1-DAZL_RFTN1_chr3_16450882_ENST00000432519_DAZL_chr3_16636090_ENST00000250863_length(transcript)=2602nt_BP=416nt
CTCGTACAGTCCTTCATCTTCATGGCAGAAAGGCTGTTCTGCCCCTGCGCCCTCCCTGGCCTCTCTGGGGATCCCTGCAGCTGATGTATT
GTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCCGCCCAGC
TCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGC
ACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTAGATTGCT
GTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGATGCCACCACAGTGGCCTGTTGGGGAGCAAAGGA
GCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAGCTGAAGTTGTGCCAAATGAATGTTCAG
TTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATACAAACGGTGGTATCTTGTCTGTTTAATC
CAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGCATCACTTTAGAAGAAGTCGGGCAATGC
TTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATATTAAGCTAAAAGGTTTCCACTATTATAGAA
ATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCTAGTTTTATCTTAAACTGTTCTTCATTAGA
TGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGACTGAAAGAAACTAAGATTTATCTGCAAGGA
TTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTTTTAAAAACCTATTTTGAAAGGTCAGAATT
TTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATTTACAGTATTGAGCTTTGCATTTATGATTT
CTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCAATATATAGTTAGCTTTATTGAAGTCTTCT
TATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTATTCAAAATATTTTATCTTTTAGCTAGAATC
CACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAATTTTTTAAAGAATCCAAGACAAACTAAAC
TTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTTCTTTGAAATGCTAAACTTGGCTGTATGTC
AAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTAATCAGAGTATCTGAAGGGAATTGTTTTTA
TAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTTGTAAAGTAAAATATGTCCAGAAGAGTCAA
AGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAATGTGCTAGAGTTAAAAGTTAGCATTGTTTC
TAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTTGCTATACCACAGTCTTTCGTTTCCAGCCT
TTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGCTGTATGAGCAGAGCAGTTCAAGGGCCAAA
CCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCATTTGATCTGCCATGGACATGAGTTTAAAG
CGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATGTAGTTACTGTGAGCCATATTACTAGTGCC
CCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAACTTTAGAATTCCCAAGAGGGCTTTATTACA
CCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGTGCTATAACATTCTGACACATATCATTCTG
TGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTATTCCAATATGACCTTAAGGAAAAGTAAGGG
AATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAGTCCTGAACCTTTCAAAATGGAAAATTAAT

>73661_73661_3_RFTN1-DAZL_RFTN1_chr3_16450882_ENST00000432519_DAZL_chr3_16636090_ENST00000250863_length(amino acids)=231AA_BP=125
MPLRPPWPLWGSLQLMYCDGAVDLDAAAELPGSSAVRLASLRDLPAQLLELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDR
SQKTDLHNEGYILELDCCSSLDHPTDQKLIPEFIKKMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQ

--------------------------------------------------------------
>73661_73661_4_RFTN1-DAZL_RFTN1_chr3_16450882_ENST00000432519_DAZL_chr3_16636090_ENST00000399444_length(transcript)=2602nt_BP=416nt
CTCGTACAGTCCTTCATCTTCATGGCAGAAAGGCTGTTCTGCCCCTGCGCCCTCCCTGGCCTCTCTGGGGATCCCTGCAGCTGATGTATT
GTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCCGCCCAGC
TCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGC
ACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTAGATTGCT
GTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGATGCCACCACAGTGGCCTGTTGGGGAGCAAAGGA
GCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAGCTGAAGTTGTGCCAAATGAATGTTCAG
TTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATACAAACGGTGGTATCTTGTCTGTTTAATC
CAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGCATCACTTTAGAAGAAGTCGGGCAATGC
TTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATATTAAGCTAAAAGGTTTCCACTATTATAGAA
ATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCTAGTTTTATCTTAAACTGTTCTTCATTAGA
TGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGACTGAAAGAAACTAAGATTTATCTGCAAGGA
TTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTTTTAAAAACCTATTTTGAAAGGTCAGAATT
TTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATTTACAGTATTGAGCTTTGCATTTATGATTT
CTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCAATATATAGTTAGCTTTATTGAAGTCTTCT
TATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTATTCAAAATATTTTATCTTTTAGCTAGAATC
CACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAATTTTTTAAAGAATCCAAGACAAACTAAAC
TTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTTCTTTGAAATGCTAAACTTGGCTGTATGTC
AAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTAATCAGAGTATCTGAAGGGAATTGTTTTTA
TAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTTGTAAAGTAAAATATGTCCAGAAGAGTCAA
AGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAATGTGCTAGAGTTAAAAGTTAGCATTGTTTC
TAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTTGCTATACCACAGTCTTTCGTTTCCAGCCT
TTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGCTGTATGAGCAGAGCAGTTCAAGGGCCAAA
CCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCATTTGATCTGCCATGGACATGAGTTTAAAG
CGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATGTAGTTACTGTGAGCCATATTACTAGTGCC
CCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAACTTTAGAATTCCCAAGAGGGCTTTATTACA
CCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGTGCTATAACATTCTGACACATATCATTCTG
TGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTATTCCAATATGACCTTAAGGAAAAGTAAGGG
AATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAGTCCTGAACCTTTCAAAATGGAAAATTAAT

>73661_73661_4_RFTN1-DAZL_RFTN1_chr3_16450882_ENST00000432519_DAZL_chr3_16636090_ENST00000399444_length(amino acids)=231AA_BP=125
MPLRPPWPLWGSLQLMYCDGAVDLDAAAELPGSSAVRLASLRDLPAQLLELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDR
SQKTDLHNEGYILELDCCSSLDHPTDQKLIPEFIKKMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQ

--------------------------------------------------------------
>73661_73661_5_RFTN1-DAZL_RFTN1_chr3_16450882_ENST00000432519_DAZL_chr3_16640105_ENST00000250863_length(transcript)=3169nt_BP=416nt
CTCGTACAGTCCTTCATCTTCATGGCAGAAAGGCTGTTCTGCCCCTGCGCCCTCCCTGGCCTCTCTGGGGATCCCTGCAGCTGATGTATT
GTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCCGCCCAGC
TCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGC
ACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTAGATTGCT
GTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGTCTACTGCAAATCCTGAAACTCCAAACTCAACCA
TCTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGTTT
TTGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAATCA
CTGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAATT
TCCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAATC
ATCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAACTC
AGTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCCAC
CACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAG
CTGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATAC
AAACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGC
ATCACTTTAGAAGAAGTCGGGCAATGCTTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATATTA
AGCTAAAAGGTTTCCACTATTATAGAAATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCTAG
TTTTATCTTAAACTGTTCTTCATTAGATGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGACTG
AAAGAAACTAAGATTTATCTGCAAGGATTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTTTT
AAAAACCTATTTTGAAAGGTCAGAATTTTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATTTA
CAGTATTGAGCTTTGCATTTATGATTTCTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCAAT
ATATAGTTAGCTTTATTGAAGTCTTCTTATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTATTC
AAAATATTTTATCTTTTAGCTAGAATCCACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAATT
TTTTAAAGAATCCAAGACAAACTAAACTTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTTCT
TTGAAATGCTAAACTTGGCTGTATGTCAAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTAAT
CAGAGTATCTGAAGGGAATTGTTTTTATAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTTGT
AAAGTAAAATATGTCCAGAAGAGTCAAAGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAATGT
GCTAGAGTTAAAAGTTAGCATTGTTTCTAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTTGC
TATACCACAGTCTTTCGTTTCCAGCCTTTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGCTG
TATGAGCAGAGCAGTTCAAGGGCCAAACCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCATT
TGATCTGCCATGGACATGAGTTTAAAGCGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATGTA
GTTACTGTGAGCCATATTACTAGTGCCCCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAACTT
TAGAATTCCCAAGAGGGCTTTATTACACCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGTGC
TATAACATTCTGACACATATCATTCTGTGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTATTC
CAATATGACCTTAAGGAAAAGTAAGGGAATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAGTC
CTGAACCTTTCAAAATGGAAAATTAATTCTAAACTTAGAAATATGCTTCTGCCTATTGCTGATACTGTCTTTGCATACATGAATAAAAAT

>73661_73661_5_RFTN1-DAZL_RFTN1_chr3_16450882_ENST00000432519_DAZL_chr3_16640105_ENST00000250863_length(amino acids)=420AA_BP=126
MPLRPPWPLWGSLQLMYCDGAVDLDAAAELPGSSAVRLASLRDLPAQLLELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDR
SQKTDLHNEGYILELDCCSSLDHPTDQKLIPEFIKKSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETE
IRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTN
PNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEA

--------------------------------------------------------------
>73661_73661_6_RFTN1-DAZL_RFTN1_chr3_16450882_ENST00000432519_DAZL_chr3_16640105_ENST00000399444_length(transcript)=3169nt_BP=416nt
CTCGTACAGTCCTTCATCTTCATGGCAGAAAGGCTGTTCTGCCCCTGCGCCCTCCCTGGCCTCTCTGGGGATCCCTGCAGCTGATGTATT
GTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCCGCCCAGC
TCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGC
ACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTAGATTGCT
GTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGTCTACTGCAAATCCTGAAACTCCAAACTCAACCA
TCTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGTTT
TTGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAATCA
CTGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAATT
TCCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAATC
ATCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAACTC
AGTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCCAC
CACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAG
CTGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATAC
AAACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGC
ATCACTTTAGAAGAAGTCGGGCAATGCTTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATATTA
AGCTAAAAGGTTTCCACTATTATAGAAATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCTAG
TTTTATCTTAAACTGTTCTTCATTAGATGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGACTG
AAAGAAACTAAGATTTATCTGCAAGGATTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTTTT
AAAAACCTATTTTGAAAGGTCAGAATTTTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATTTA
CAGTATTGAGCTTTGCATTTATGATTTCTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCAAT
ATATAGTTAGCTTTATTGAAGTCTTCTTATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTATTC
AAAATATTTTATCTTTTAGCTAGAATCCACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAATT
TTTTAAAGAATCCAAGACAAACTAAACTTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTTCT
TTGAAATGCTAAACTTGGCTGTATGTCAAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTAAT
CAGAGTATCTGAAGGGAATTGTTTTTATAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTTGT
AAAGTAAAATATGTCCAGAAGAGTCAAAGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAATGT
GCTAGAGTTAAAAGTTAGCATTGTTTCTAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTTGC
TATACCACAGTCTTTCGTTTCCAGCCTTTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGCTG
TATGAGCAGAGCAGTTCAAGGGCCAAACCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCATT
TGATCTGCCATGGACATGAGTTTAAAGCGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATGTA
GTTACTGTGAGCCATATTACTAGTGCCCCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAACTT
TAGAATTCCCAAGAGGGCTTTATTACACCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGTGC
TATAACATTCTGACACATATCATTCTGTGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTATTC
CAATATGACCTTAAGGAAAAGTAAGGGAATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAGTC
CTGAACCTTTCAAAATGGAAAATTAATTCTAAACTTAGAAATATGCTTCTGCCTATTGCTGATACTGTCTTTGCATACATGAATAAAAAT

>73661_73661_6_RFTN1-DAZL_RFTN1_chr3_16450882_ENST00000432519_DAZL_chr3_16640105_ENST00000399444_length(amino acids)=420AA_BP=126
MPLRPPWPLWGSLQLMYCDGAVDLDAAAELPGSSAVRLASLRDLPAQLLELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDR
SQKTDLHNEGYILELDCCSSLDHPTDQKLIPEFIKKSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETE
IRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTN
PNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEA

--------------------------------------------------------------
>73661_73661_7_RFTN1-DAZL_RFTN1_chr3_16535232_ENST00000334133_DAZL_chr3_16640105_ENST00000250863_length(transcript)=3171nt_BP=418nt
CGTCGGGGCTGGAGCCGGAGCGCGCCGGGCGCTGGGCGCAGCGAGCGAGAGCGCGGCGGCCGCGGGCTCCGGCGAGGGACAGACGCACCG
ATCGCCGGAGGGACAGACACACGACCACGCGGCGCCACCGCCCACGCCTCCACCCACCGGCGCCCAAGTCCTCCCCGCGCCGCCTCCTCT
GTATGGCACAAACTTTCCTCCCGGGACGGAACACGCTGCCTCAGGGAGCCCGCGACCGCGCCTTCTCCTCCGCCGGTCCCATACGCTGCT
GAAATGGGTTGCGGATTGAACAAGTTAGAGAAACGTGATGAAAAACGGCCTGGGAATATTTATTCAACTTTGAAGAGGCCTCAGGTGGAA
ACCAAGATAGATGTGTCCTATGAATACCGCTTCCTGGAGTTCACGACTCTGAGTGCTGTCTACTGCAAATCCTGAAACTCCAAACTCAAC
CATCTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGT
TTTTGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAAT
CACTGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAA
TTTCCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAA
TCATCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAAC
TCAGTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCC
ACCACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGG
AGCTGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCAT
ACAAACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGT
GCATCACTTTAGAAGAAGTCGGGCAATGCTTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATAT
TAAGCTAAAAGGTTTCCACTATTATAGAAATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCT
AGTTTTATCTTAAACTGTTCTTCATTAGATGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGAC
TGAAAGAAACTAAGATTTATCTGCAAGGATTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTT
TTAAAAACCTATTTTGAAAGGTCAGAATTTTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATT
TACAGTATTGAGCTTTGCATTTATGATTTCTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCA
ATATATAGTTAGCTTTATTGAAGTCTTCTTATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTAT
TCAAAATATTTTATCTTTTAGCTAGAATCCACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAA
TTTTTTAAAGAATCCAAGACAAACTAAACTTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTT
CTTTGAAATGCTAAACTTGGCTGTATGTCAAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTA
ATCAGAGTATCTGAAGGGAATTGTTTTTATAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTT
GTAAAGTAAAATATGTCCAGAAGAGTCAAAGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAAT
GTGCTAGAGTTAAAAGTTAGCATTGTTTCTAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTT
GCTATACCACAGTCTTTCGTTTCCAGCCTTTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGC
TGTATGAGCAGAGCAGTTCAAGGGCCAAACCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCA
TTTGATCTGCCATGGACATGAGTTTAAAGCGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATG
TAGTTACTGTGAGCCATATTACTAGTGCCCCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAAC
TTTAGAATTCCCAAGAGGGCTTTATTACACCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGT
GCTATAACATTCTGACACATATCATTCTGTGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTAT
TCCAATATGACCTTAAGGAAAAGTAAGGGAATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAG
TCCTGAACCTTTCAAAATGGAAAATTAATTCTAAACTTAGAAATATGCTTCTGCCTATTGCTGATACTGTCTTTGCATACATGAATAAAA

>73661_73661_7_RFTN1-DAZL_RFTN1_chr3_16535232_ENST00000334133_DAZL_chr3_16640105_ENST00000250863_length(amino acids)=295AA_BP=1
MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFND
VDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSV

--------------------------------------------------------------
>73661_73661_8_RFTN1-DAZL_RFTN1_chr3_16535232_ENST00000334133_DAZL_chr3_16640105_ENST00000399444_length(transcript)=3171nt_BP=418nt
CGTCGGGGCTGGAGCCGGAGCGCGCCGGGCGCTGGGCGCAGCGAGCGAGAGCGCGGCGGCCGCGGGCTCCGGCGAGGGACAGACGCACCG
ATCGCCGGAGGGACAGACACACGACCACGCGGCGCCACCGCCCACGCCTCCACCCACCGGCGCCCAAGTCCTCCCCGCGCCGCCTCCTCT
GTATGGCACAAACTTTCCTCCCGGGACGGAACACGCTGCCTCAGGGAGCCCGCGACCGCGCCTTCTCCTCCGCCGGTCCCATACGCTGCT
GAAATGGGTTGCGGATTGAACAAGTTAGAGAAACGTGATGAAAAACGGCCTGGGAATATTTATTCAACTTTGAAGAGGCCTCAGGTGGAA
ACCAAGATAGATGTGTCCTATGAATACCGCTTCCTGGAGTTCACGACTCTGAGTGCTGTCTACTGCAAATCCTGAAACTCCAAACTCAAC
CATCTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGT
TTTTGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAAT
CACTGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAA
TTTCCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAA
TCATCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAAC
TCAGTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCC
ACCACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGG
AGCTGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCAT
ACAAACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGT
GCATCACTTTAGAAGAAGTCGGGCAATGCTTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATAT
TAAGCTAAAAGGTTTCCACTATTATAGAAATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCT
AGTTTTATCTTAAACTGTTCTTCATTAGATGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGAC
TGAAAGAAACTAAGATTTATCTGCAAGGATTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTT
TTAAAAACCTATTTTGAAAGGTCAGAATTTTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATT
TACAGTATTGAGCTTTGCATTTATGATTTCTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCA
ATATATAGTTAGCTTTATTGAAGTCTTCTTATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTAT
TCAAAATATTTTATCTTTTAGCTAGAATCCACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAA
TTTTTTAAAGAATCCAAGACAAACTAAACTTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTT
CTTTGAAATGCTAAACTTGGCTGTATGTCAAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTA
ATCAGAGTATCTGAAGGGAATTGTTTTTATAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTT
GTAAAGTAAAATATGTCCAGAAGAGTCAAAGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAAT
GTGCTAGAGTTAAAAGTTAGCATTGTTTCTAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTT
GCTATACCACAGTCTTTCGTTTCCAGCCTTTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGC
TGTATGAGCAGAGCAGTTCAAGGGCCAAACCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCA
TTTGATCTGCCATGGACATGAGTTTAAAGCGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATG
TAGTTACTGTGAGCCATATTACTAGTGCCCCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAAC
TTTAGAATTCCCAAGAGGGCTTTATTACACCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGT
GCTATAACATTCTGACACATATCATTCTGTGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTAT
TCCAATATGACCTTAAGGAAAAGTAAGGGAATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAG
TCCTGAACCTTTCAAAATGGAAAATTAATTCTAAACTTAGAAATATGCTTCTGCCTATTGCTGATACTGTCTTTGCATACATGAATAAAA

>73661_73661_8_RFTN1-DAZL_RFTN1_chr3_16535232_ENST00000334133_DAZL_chr3_16640105_ENST00000399444_length(amino acids)=295AA_BP=1
MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFND
VDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RFTN1-DAZL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RFTN1-DAZL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RFTN1-DAZL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource