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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:RGS3-BSPRY (FusionGDB2 ID:73824)

Fusion Gene Summary for RGS3-BSPRY

Fusion gene summary

Fusion gene information	Fusion gene name: RGS3-BSPRY
	Fusion gene ID: 73824
		Hgene	Tgene
	Gene symbol	RGS3	BSPRY
	Gene ID	5998	54836
	Gene name	regulator of G protein signaling 3	B-box and SPRY domain containing
	Synonyms	C2PA\|RGP3	-
	Cytomap	9q32	9q32
	Type of gene	protein-coding	protein-coding
	Description	regulator of G-protein signaling 3regulator of G-protein signalling 3	B box and SPRY domain-containing proteinB-box and SPRY-domain containing proteinzetin 1
	Modification date	20200320	20200320
	UniProtAcc	.	Q5W0U4
	Ensembl transtripts involved in fusion gene	ENST00000343817, ENST00000350696, ENST00000374134, ENST00000374140, ENST00000462143, ENST00000317613, ENST00000342620, ENST00000374136, ENST00000394646, ENST00000462403, ENST00000463806,	ENST00000462085, ENST00000374183,
Fusion gene scores	* DoF score	5 X 5 X 5=125	5 X 5 X 3=75
	# samples	7	6
	** MAII score	log2(7/125*10)=-0.836501267717121 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(6/75*10)=-0.321928094887362 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: RGS3 [Title/Abstract] AND BSPRY [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	RGS3(116226161)-BSPRY(116130539), # samples:3 RGS3(116346707)-BSPRY(116116520), # samples:3
Anticipated loss of major functional domain due to fusion event.	RGS3-BSPRY seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across RGS3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across BSPRY (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LUAD	TCGA-05-4427-01A	RGS3	chr9	116226161	-	BSPRY	chr9	116130539	+
ChimerDB4	LUAD	TCGA-05-4427-01A	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
ChimerDB4	UCEC	TCGA-E6-A8L9-01A	RGS3	chr9	116346707	-	BSPRY	chr9	116116520	+
ChimerDB4	UCEC	TCGA-E6-A8L9-01A	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+

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Fusion Gene ORF analysis for RGS3-BSPRY

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000343817	ENST00000462085	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
5CDS-3UTR	ENST00000350696	ENST00000462085	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
5CDS-3UTR	ENST00000374134	ENST00000462085	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
5CDS-3UTR	ENST00000374140	ENST00000462085	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
5CDS-3UTR	ENST00000462143	ENST00000462085	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
5CDS-intron	ENST00000317613	ENST00000462085	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
Frame-shift	ENST00000317613	ENST00000374183	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
In-frame	ENST00000343817	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
In-frame	ENST00000350696	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
In-frame	ENST00000374134	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
In-frame	ENST00000374140	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
In-frame	ENST00000462143	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3CDS	ENST00000317613	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3CDS	ENST00000342620	ENST00000374183	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-3CDS	ENST00000342620	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3CDS	ENST00000343817	ENST00000374183	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-3CDS	ENST00000350696	ENST00000374183	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-3CDS	ENST00000374134	ENST00000374183	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-3CDS	ENST00000374136	ENST00000374183	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-3CDS	ENST00000374136	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3CDS	ENST00000374140	ENST00000374183	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-3CDS	ENST00000394646	ENST00000374183	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-3CDS	ENST00000394646	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3CDS	ENST00000462143	ENST00000374183	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-3CDS	ENST00000462403	ENST00000374183	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-3CDS	ENST00000462403	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3CDS	ENST00000463806	ENST00000374183	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-3CDS	ENST00000463806	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3UTR	ENST00000317613	ENST00000462085	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3UTR	ENST00000342620	ENST00000462085	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3UTR	ENST00000374136	ENST00000462085	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3UTR	ENST00000394646	ENST00000462085	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3UTR	ENST00000462403	ENST00000462085	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-3UTR	ENST00000463806	ENST00000462085	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+
intron-intron	ENST00000342620	ENST00000462085	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-intron	ENST00000343817	ENST00000462085	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-intron	ENST00000350696	ENST00000462085	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-intron	ENST00000374134	ENST00000462085	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-intron	ENST00000374136	ENST00000462085	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-intron	ENST00000374140	ENST00000462085	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-intron	ENST00000394646	ENST00000462085	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-intron	ENST00000462143	ENST00000462085	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-intron	ENST00000462403	ENST00000462085	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+
intron-intron	ENST00000463806	ENST00000462085	RGS3	chr9	116226161	+	BSPRY	chr9	116130539	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

ENST00000374140

RGS3

chr9

116346707

ENST00000374183

BSPRY

chr9

116116520

5323

3224

209

4231

1340

ENST00000350696

RGS3

chr9

116346707

ENST00000374183

BSPRY

chr9

116116520

5131

3032

4039

1340

ENST00000343817

RGS3

chr9

116346707

ENST00000374183

BSPRY

chr9

116116520

4421

2322

3329

1086

ENST00000462143

RGS3

chr9

116346707

ENST00000374183

BSPRY

chr9

116116520

3492

1393

313

2400

695

ENST00000374134

RGS3

chr9

116346707

ENST00000374183

BSPRY

chr9

116116520

3594

1495

517

2502

661

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000374140	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+	0.002814746	0.9971853
ENST00000350696	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+	0.00249996	0.9975
ENST00000343817	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+	0.002440342	0.99755967
ENST00000462143	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+	0.006767472	0.9932326
ENST00000374134	ENST00000374183	RGS3	chr9	116346707	+	BSPRY	chr9	116116520	+	0.005315968	0.99468404

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Fusion Genomic Features for RGS3-BSPRY

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
RGS3	chr9	116346707	+	BSPRY	chr9	116116519	+	0.001016438	0.99898356
RGS3	chr9	116226161	+	BSPRY	chr9	116130538	+	0.00099834	0.9990017
RGS3	chr9	116346707	+	BSPRY	chr9	116116519	+	0.001016438	0.99898356
RGS3	chr9	116226161	+	BSPRY	chr9	116130538	+	0.00099834	0.9990017

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RGS3-BSPRY

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:116226161/chr9:116130539)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	BSPRY Q5W0U4
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: May regulate epithelial calcium transport by inhibiting TRPV5 activity. {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000350696

705_819

1005

1199.0

Compositional bias

Note=Pro-rich

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000374140

705_819

1005

1199.0

Compositional bias

Note=Pro-rich

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000343817

137_256

724

918.0

Domain

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000343817

299_376

724

918.0

Domain

PDZ

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000350696

137_256

1005

1199.0

Domain

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000350696

299_376

1005

1199.0

Domain

PDZ

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000374134

137_256

326

520.0

Domain

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000374140

137_256

1005

1199.0

Domain

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000374140

299_376

1005

1199.0

Domain

PDZ

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000462143

137_256

326

520.0

Domain

Tgene

BSPRY

chr9:116346707

chr9:116116520

ENST00000374183

212_402

403.0

Domain

B30.2/SPRY

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000317613

705_819

603.0

Compositional bias

Note=Pro-rich

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000343817

705_819

724

918.0

Compositional bias

Note=Pro-rich

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000374134

705_819

326

520.0

Compositional bias

Note=Pro-rich

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000462143

705_819

326

520.0

Compositional bias

Note=Pro-rich

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000462403

705_819

312.0

Compositional bias

Note=Pro-rich

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000317613

1073_1198

603.0

Domain

RGS

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000317613

137_256

603.0

Domain

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000317613

299_376

603.0

Domain

PDZ

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000343817

1073_1198

724

918.0

Domain

RGS

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000350696

1073_1198

1005

1199.0

Domain

RGS

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000374134

1073_1198

326

520.0

Domain

RGS

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000374134

299_376

326

520.0

Domain

PDZ

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000374140

1073_1198

1005

1199.0

Domain

RGS

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000462143

1073_1198

326

520.0

Domain

RGS

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000462143

299_376

326

520.0

Domain

PDZ

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000462403

1073_1198

312.0

Domain

RGS

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000462403

137_256

312.0

Domain

Hgene

RGS3

chr9:116346707

chr9:116116520

ENST00000462403

299_376

312.0

Domain

PDZ

Tgene

BSPRY

chr9:116346707

chr9:116116520

ENST00000374183

17_65

403.0

Zinc finger

Note=B box-type

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Fusion Gene Sequence for RGS3-BSPRY

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>73824_73824_1_RGS3-BSPRY_RGS3_chr9_116346707_ENST00000343817_BSPRY_chr9_116116520_ENST00000374183_length(transcript)=4421nt_BP=2322nt
TTGGGGAGGTGAGAGGTGATTTCCTGCCATTCTTCTGTGGGGCGGGCTTCCCAGGGTGCTCATGCCAGGCTGACGGGTCCAGTGCGGGCT
CCCGCTGCTGGGGGAGAGCTGGGTTTTCATGGGGCGGCAGCCGAGGCAGGACCCGCAGCCATGAACCGCTTCAATGGGCTCTGCAAGGTG
TGCTCGGAGCGCCGCTACCGCCAGATCACCATCCCGAGGGGAAAGGACGGCTTTGGCTTCACCATCTGCTGCGACTCTCCAGTTCGAGTC
CAGGCCGTGGATTCCGGGGGTCCGGCGGAACGGGCAGGGCTGCAGCAGCTGGACACGGTGCTGCAGCTGAATGAGAGGCCTGTGGAGCAC
TGGAAATGTGTGGAGCTGGCCCACGAGATCCGGAGCTGCCCCAGTGAGATCATCCTACTCGTGTGGCGCATGGTCCCCCAGGTCAAGCCA
GGACCAGATGGCGGGGTCCTGCGGCGGGCCTCCTGCAAGTCGACACATGACCTCCAGTCACCCCCCAACAAACGGGAGAAGAACTGCACC
CATGGGGTCCAGGCACGGCCTGAGCAGCGCCACAGCTGCCACCTGGTATGTGACAGCTCTGATGGGCTGCTGCTCGGCGGCTGGGAGCGC
TACACCGAGGTGGCCAAGCGCGGGGGCCAGCACACCCTGCCTGCACTGTCCCGTGCCACTGCCCCCACCGACCCCAACTACATCATCCTG
GCCCCGCTGAATCCTGGGAGCCAGCTGCTCCGGCCTGTGTACCAGGAGGATACCATCCCCGAAGAATCAGGGAGTCCCAGTAAAGGGAAG
TCCTACACAGGCCTGGGGAAGAAGTCCCGGCTGATGAAGACAGTGCAGACCATGAAGGGCCACGGGAACTACCAAAACTGCCCGGTTGTG
AGGCCGCATGCCACGCACTCAAGCTATGGCACCTACGTCACCCTGGCCCCCAAAGTCCTGGTGTTCCCTGTCTTTGTTCAGCCTCTAGAT
CTCTGTAATCCTGCCCGGACCCTCCTGCTGTCAGAGGAGCTGCTGCTGTATGAAGGGAGGAACAAGGCTGCCGAGGTGACACTGTTTGCC
TATTCGGACCTGCTGCTCTTCACCAAGGAGGACGAGCCTGGCCGCTGCGACGTCCTGAGGAACCCCCTCTACCTCCAGAGTGTGAAGCTG
CAGGAAGGTTCTTCAGAAGACCTGAAATTCTGCGTGCTCTATCTAGCAGAGAAGGCAGAGTGCTTATTCACTTTGGAAGCGCACTCGCAG
GAGCAGAAGAAGAGAGTGTGCTGGTGCCTGTCGGAGAACATCGCCAAGCAGCAACAGCTGGCAGCATCACCCCCGGACAGCAAGATGTTT
GAGACGGAGGCAGATGAGAAGAGGGAGATGGCCTTGGAGGAAGGGAAGGGGCCTGGTGCCGAGGATTCCCCACCCAGCAAGGAGCCCTCT
CCTGGCCAGGAGCTTCCTCCAGGACAAGACCTTCCACCCAACAAGGACTCCCCTTCTGGGCAGGAACCCGCTCCCAGCCAAGAACCACTG
TCCAGCAAAGACTCAGCTACCTCTGAAGGATCCCCTCCAGGCCCAGATGCTCCGCCCAGCAAGGATGTGCCACCATGCCAGGAACCCCCT
CCAGCCCAAGACCTCTCACCCTGCCAGGACCTACCTGCTGGTCAAGAACCCCTGCCTCACCAGGACCCTCTACTCACCAAAGACCTCCCT
GCCATCCAGGAATCCCCCACCCGGGACCTTCCACCCTGTCAAGATCTGCCTCCTAGCCAGGTCTCCCTGCCAGCCAAGGCCCTTACTGAG
GACACCATGAGCTCCGGGGACCTACTAGCAGCTACTGGGGACCCACCTGCGGCCCCCAGGCCAGCCTTCGTGATCCCTGAGGTCCGGCTG
GATAGCACCTACAGCCAGAAGGCAGGGGCAGAGCAGGGCTGCTCGGGAGATGAGGAGGATGCAGAAGAGGCCGAGGAGGTGGAGGAGGGG
GAGGAAGGGGAGGAGGACGAGGATGAGGACACCAGCGATGACAACTACGGAGAGCGCAGTGAGGCCAAGCGCAGCAGCATGATCGAGACG
GGCCAGGGGGCTGAGGGTGGCCTCTCACTGCGTGTGCAGAACTCGCTGCGGCGCCGGACGCACAGCGAGGGCAGCCTGCTGCAGGAGCCC
CGAGGGCCCTGCTTTGCCTCCGACACCACCTTGCACTGCTCAGACGGTGAGGGCGCCGCCTCCACCTGGGGCATGCCTTCGCCCAGCACC
CTCAAGAAAGAGCTGGGCCGCAATGGTGGCTCCATGCACCACCTTTCCCTCTTCTTCACAGGACACAGGAAGAACAAGATTGTGGACCAG
TGTGAGAGGCTGCAGTTACAGAGTGCTGCCATCACCAAGTATGTGGCGGACGTCCTGCCGGGGAAGAATCAAAGAGCAGTGAGCATGGCC
AGTGCAGCGAGGGAACTGGTTATCCAGCGGTTGAGTCTGGTGAGGAGTCTTTGCGAGAGCGAGGAGCAGCGGTTACTGGAACAGGTGCAT
GGCGAAGAGGAGCGGGCCCACCAGAGCATCCTGACACAGCGGGTGCACTGGGCCGAGGCGCTGCAGAAACTTGACACCATCCGCACTGGC
CTGGTGGGCATGCTTACTCACCTGGATGACCTCCAGCTGATTCAGAAGGAGCAAGAGATTTTCGAGAGGACCGAAGAAGCAGAGGGCATT
TTGGATCCCCAGGAGTCGGAAATGTTAAACTTTAATGAGAAGTGCACTCGGAGCCCACTACTGACCCAACTCTGGGCAACGGCGGTTCTT
GGGTCTCTCTCAGGCACAGAGGACATACGGATCGATGAGAGGACAGTCAGCCCCTTCCTGCAATTGTCAGATGATCGAAAGACCCTGACC
TTCAGCACCAAGAAGTCAAAGGCCTGTGCAGATGGCCCGGAGCGCTTCGACCACTGGCCCAATGCCCTGGCTGCCACCTCCTTCCAGAAT
GGGCTCCATGCCTGGATGGTGAATGTCCAGAACAGTTGTGCCTATAAGGTGGGCGTGGCTTCAGGCCACCTGCCCCGCAAGGGTTCTGGC
AGTGACTGCCGTCTGGGCCACAATGCCTTCTCCTGGGTCTTCTCTCGCTATGATCAGGAGTTTCGTTTCTCACACAATGGGCAGCACGAG
CCCCTGGGGCTGCTGCGGGGCCCAGCCCAGCTGGGTGTAGTGCTGGACTTGCAGGTTCAGGAGCTGCTCTTCTATGAGCCAGCCTCCGGC
ACAGTGCTCTGTGCCCATCATGTGTCCTTCCCGGGGCCCCTCTTCCCAGTCTTTGCTGTGGCCGATCAGACCATTTCTATCGTCCGCTGA
CCTCTGGCCACAGGAAGCCAGGTCCACCGCCCACCACCCTTTCAGGCCATGTTTCTACTCAGTGTGCTTTTCCCAAATGATGTGTGTGGT
GTTTCTAAGAGAAACAGGGCCCATAACCAGTGGGCAGCTTTAGGAGGGATGGGGATCTGTTTCAGATCTAGGCATAACCTGTAAATCACA
GGTGTCCAAACTTTTGGCTTCCCTGGGCCACATTTGAAGAAGAATTTTCTTGGGCCACATAAAATACACTAACGATAGCTGATGAGCTAA
AAAAAAAAAAAAAGTCTGTGTATAATTTTTGTGATATCTGCCACCACAGATAAGCAAAAAAGTCCTTGCATTCAAAGGGTTGGAGATTGC
TGCTTTGAGTGCTGGGTACCTGTGGGGAACCTACTACTCCCTGGGCCTTAGTCTCCCAAATCCACCATGCATCTGCCCCTCTGAGGGTGT
CTTCACTTTGTCTCTGGCATCTAGCATGGTGCCTGGTGCATAGTGAGCATGCAATAAATATTTGGCAGGTGAGTGGATGGATAGATGGAT
AGGTGAATGTAGGTGGACAGGTGACTGGGTGGATGTTGTGGTCTCTGGAGAAGCACTGCCATTCAGCCTCCTGCTCCAGCTGTTCACATG
CAGAAATGCTCTCTTCACAGGCAGAGAAGCCTGTGGCTAAAGTTTCCACATCCCATTAACTCAGTGCTTTTGTCTTTTTCATGACATGGC
ACATAGAGAAAATATTTTTTTCTAGCACACAAGAGCAACCTGAAAGGCTGCTCCTGGCCAGAGGACTCTGTCCCGGGGGACCGTGTCCTC
CCCCATGTCCTGCCTAGGCCCTCAGAGGACCAGGGGATCATGTCTCCAGGTAACCCGACTGTAGCCCCTGCTGGCTGAGCTCCAGCCTGT
GCCCACTGATAATAGCAGGGACGGCCTTTTCTCTTAGAGCAGCTGATAAGTTTCCCTACCTGATGGCCCCCTCTGACATAAACTGCACAC
CTGGGGTGATGGCTTAAAGCCAGAAAGAGCTGAGGGAGTTAAGAGGGCCAACCTTAGGGCACGTGGGCATTATTAAAGGTCTTAAAAGCA

>73824_73824_1_RGS3-BSPRY_RGS3_chr9_116346707_ENST00000343817_BSPRY_chr9_116116520_ENST00000374183_length(amino acids)=1086AA_BP=751
MTGPVRAPAAGGELGFHGAAAEAGPAAMNRFNGLCKVCSERRYRQITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQL
NERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARPEQRHSCHLVCDSSDGL
LLGGWERYTEVAKRGGQHTLPALSRATAPTDPNYIILAPLNPGSQLLRPVYQEDTIPEESGSPSKGKSYTGLGKKSRLMKTVQTMKGHGN
YQNCPVVRPHATHSSYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLFTKEDEPGRCDVLRNPL
YLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAASPPDSKMFETEADEKREMALEEGKGPGAEDS
PPSKEPSPGQELPPGQDLPPNKDSPSGQEPAPSQEPLSSKDSATSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDP
LLTKDLPAIQESPTRDLPPCQDLPPSQVSLPAKALTEDTMSSGDLLAATGDPPAAPRPAFVIPEVRLDSTYSQKAGAEQGCSGDEEDAEE
AEEVEEGEEGEEDEDEDTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAASTW
GMPSPSTLKKELGRNGGSMHHLSLFFTGHRKNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQ
RLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQ
LWATAVLGSLSGTEDIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGH
LPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASGTVLCAHHVSFPGPLFPVFAVADQ

--------------------------------------------------------------
>73824_73824_2_RGS3-BSPRY_RGS3_chr9_116346707_ENST00000350696_BSPRY_chr9_116116520_ENST00000374183_length(transcript)=5131nt_BP=3032nt
GCCAGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGTTGAGATGGGCAGATCGCAAGGTCAGGAGATCGAGACCATCCTGG
CTAACAGGTCACATTCAGACAGCACACCTTTGCCCAATTTTCTTTCTGGATCTCACCGTCCTGAGTGTTGTACCTGCAGGTTGCTCACAG
CCTCTGGAGCCCAAGATAGTCTCCCCTTTGGGAGGAGGCTCTACAGTGGTCCCTGGCGAAGTTGTGAAGAGGTCTGCCACGTCTCTGTGC
TCAGTGTCCTCTCTACATCCTGTGGCTTGAGCCTGAGCTTGCCCATATTCCCTGGCTGGATGGAGTGGCTAAGCCCTGATATCGCTCTGC
CCAGAAGAGATGAGTGGACTCAAACTTCTCCAGCCAGGAAGAGGATCACGCATGCCAAAGTCCAGGGTGCAGGTCAGCTGAGGCTGTCCA
TTGATGCCCAGGACCGGGTTCTGCTGCTTCACATTATAGAAGGTAAAGGCCTGATCAGCAAACAGCCTGGCACCTGTGATCCGTATGTGA
AGATTTCTTTGATCCCTGAAGATAGTAGACTACGCCACCAGAAGACGCAGACCGTTCCAGACTGCAGAGACCCGGCTTTCCACGAGCACT
TCTTCTTTCCTGTCCAAGAGGAGGATGATCAGAAGCGTCTCTTGGTTACTGTGTGGAACAGGGCCAGCCAGTCCAGACAGAGTGGACTCA
TTGGCTGCATGAGCTTTGGGGTGAAGTCTCTCCTGACTCCAGACAAGGAGATCAGTGGTTGGTACTACCTCCTAGGGGAGCACCTGGGCC
GGACCAAGCACTTGAAGGTGGCCAGGCGGCGACTGCGGCCGCTGAGAGACCCGCTGCTGAGAATGCCAGGAGGTGGGGACACTGAGAATG
GGAAGAAACTAAAGATCACCATCCCGAGGGGAAAGGACGGCTTTGGCTTCACCATCTGCTGCGACTCTCCAGTTCGAGTCCAGGCCGTGG
ATTCCGGGGGTCCGGCGGAACGGGCAGGGCTGCAGCAGCTGGACACGGTGCTGCAGCTGAATGAGAGGCCTGTGGAGCACTGGAAATGTG
TGGAGCTGGCCCACGAGATCCGGAGCTGCCCCAGTGAGATCATCCTACTCGTGTGGCGCATGGTCCCCCAGGTCAAGCCAGGACCAGATG
GCGGGGTCCTGCGGCGGGCCTCCTGCAAGTCGACACATGACCTCCAGTCACCCCCCAACAAACGGGAGAAGAACTGCACCCATGGGGTCC
AGGCACGGCCTGAGCAGCGCCACAGCTGCCACCTGGTATGTGACAGCTCTGATGGGCTGCTGCTCGGCGGCTGGGAGCGCTACACCGAGG
TGGCCAAGCGCGGGGGCCAGCACACCCTGCCTGCACTGTCCCGTGCCACTGCCCCCACCGACCCCAACTACATCATCCTGGCCCCGCTGA
ATCCTGGGAGCCAGCTGCTCCGGCCTGTGTACCAGGAGGATACCATCCCCGAAGAATCAGGGAGTCCCAGTAAAGGGAAGTCCTACACAG
GCCTGGGGAAGAAGTCCCGGCTGATGAAGACAGTGCAGACCATGAAGGGCCACGGGAACTACCAAAACTGCCCGGTTGTGAGGCCGCATG
CCACGCACTCAAGCTATGGCACCTACGTCACCCTGGCCCCCAAAGTCCTGGTGTTCCCTGTCTTTGTTCAGCCTCTAGATCTCTGTAATC
CTGCCCGGACCCTCCTGCTGTCAGAGGAGCTGCTGCTGTATGAAGGGAGGAACAAGGCTGCCGAGGTGACACTGTTTGCCTATTCGGACC
TGCTGCTCTTCACCAAGGAGGACGAGCCTGGCCGCTGCGACGTCCTGAGGAACCCCCTCTACCTCCAGAGTGTGAAGCTGCAGGAAGGTT
CTTCAGAAGACCTGAAATTCTGCGTGCTCTATCTAGCAGAGAAGGCAGAGTGCTTATTCACTTTGGAAGCGCACTCGCAGGAGCAGAAGA
AGAGAGTGTGCTGGTGCCTGTCGGAGAACATCGCCAAGCAGCAACAGCTGGCAGCATCACCCCCGGACAGCAAGATGTTTGAGACGGAGG
CAGATGAGAAGAGGGAGATGGCCTTGGAGGAAGGGAAGGGGCCTGGTGCCGAGGATTCCCCACCCAGCAAGGAGCCCTCTCCTGGCCAGG
AGCTTCCTCCAGGACAAGACCTTCCACCCAACAAGGACTCCCCTTCTGGGCAGGAACCCGCTCCCAGCCAAGAACCACTGTCCAGCAAAG
ACTCAGCTACCTCTGAAGGATCCCCTCCAGGCCCAGATGCTCCGCCCAGCAAGGATGTGCCACCATGCCAGGAACCCCCTCCAGCCCAAG
ACCTCTCACCCTGCCAGGACCTACCTGCTGGTCAAGAACCCCTGCCTCACCAGGACCCTCTACTCACCAAAGACCTCCCTGCCATCCAGG
AATCCCCCACCCGGGACCTTCCACCCTGTCAAGATCTGCCTCCTAGCCAGGTCTCCCTGCCAGCCAAGGCCCTTACTGAGGACACCATGA
GCTCCGGGGACCTACTAGCAGCTACTGGGGACCCACCTGCGGCCCCCAGGCCAGCCTTCGTGATCCCTGAGGTCCGGCTGGATAGCACCT
ACAGCCAGAAGGCAGGGGCAGAGCAGGGCTGCTCGGGAGATGAGGAGGATGCAGAAGAGGCCGAGGAGGTGGAGGAGGGGGAGGAAGGGG
AGGAGGACGAGGATGAGGACACCAGCGATGACAACTACGGAGAGCGCAGTGAGGCCAAGCGCAGCAGCATGATCGAGACGGGCCAGGGGG
CTGAGGGTGGCCTCTCACTGCGTGTGCAGAACTCGCTGCGGCGCCGGACGCACAGCGAGGGCAGCCTGCTGCAGGAGCCCCGAGGGCCCT
GCTTTGCCTCCGACACCACCTTGCACTGCTCAGACGGTGAGGGCGCCGCCTCCACCTGGGGCATGCCTTCGCCCAGCACCCTCAAGAAAG
AGCTGGGCCGCAATGGTGGCTCCATGCACCACCTTTCCCTCTTCTTCACAGGACACAGGAAGAACAAGATTGTGGACCAGTGTGAGAGGC
TGCAGTTACAGAGTGCTGCCATCACCAAGTATGTGGCGGACGTCCTGCCGGGGAAGAATCAAAGAGCAGTGAGCATGGCCAGTGCAGCGA
GGGAACTGGTTATCCAGCGGTTGAGTCTGGTGAGGAGTCTTTGCGAGAGCGAGGAGCAGCGGTTACTGGAACAGGTGCATGGCGAAGAGG
AGCGGGCCCACCAGAGCATCCTGACACAGCGGGTGCACTGGGCCGAGGCGCTGCAGAAACTTGACACCATCCGCACTGGCCTGGTGGGCA
TGCTTACTCACCTGGATGACCTCCAGCTGATTCAGAAGGAGCAAGAGATTTTCGAGAGGACCGAAGAAGCAGAGGGCATTTTGGATCCCC
AGGAGTCGGAAATGTTAAACTTTAATGAGAAGTGCACTCGGAGCCCACTACTGACCCAACTCTGGGCAACGGCGGTTCTTGGGTCTCTCT
CAGGCACAGAGGACATACGGATCGATGAGAGGACAGTCAGCCCCTTCCTGCAATTGTCAGATGATCGAAAGACCCTGACCTTCAGCACCA
AGAAGTCAAAGGCCTGTGCAGATGGCCCGGAGCGCTTCGACCACTGGCCCAATGCCCTGGCTGCCACCTCCTTCCAGAATGGGCTCCATG
CCTGGATGGTGAATGTCCAGAACAGTTGTGCCTATAAGGTGGGCGTGGCTTCAGGCCACCTGCCCCGCAAGGGTTCTGGCAGTGACTGCC
GTCTGGGCCACAATGCCTTCTCCTGGGTCTTCTCTCGCTATGATCAGGAGTTTCGTTTCTCACACAATGGGCAGCACGAGCCCCTGGGGC
TGCTGCGGGGCCCAGCCCAGCTGGGTGTAGTGCTGGACTTGCAGGTTCAGGAGCTGCTCTTCTATGAGCCAGCCTCCGGCACAGTGCTCT
GTGCCCATCATGTGTCCTTCCCGGGGCCCCTCTTCCCAGTCTTTGCTGTGGCCGATCAGACCATTTCTATCGTCCGCTGACCTCTGGCCA
CAGGAAGCCAGGTCCACCGCCCACCACCCTTTCAGGCCATGTTTCTACTCAGTGTGCTTTTCCCAAATGATGTGTGTGGTGTTTCTAAGA
GAAACAGGGCCCATAACCAGTGGGCAGCTTTAGGAGGGATGGGGATCTGTTTCAGATCTAGGCATAACCTGTAAATCACAGGTGTCCAAA
CTTTTGGCTTCCCTGGGCCACATTTGAAGAAGAATTTTCTTGGGCCACATAAAATACACTAACGATAGCTGATGAGCTAAAAAAAAAAAA
AAAGTCTGTGTATAATTTTTGTGATATCTGCCACCACAGATAAGCAAAAAAGTCCTTGCATTCAAAGGGTTGGAGATTGCTGCTTTGAGT
GCTGGGTACCTGTGGGGAACCTACTACTCCCTGGGCCTTAGTCTCCCAAATCCACCATGCATCTGCCCCTCTGAGGGTGTCTTCACTTTG
TCTCTGGCATCTAGCATGGTGCCTGGTGCATAGTGAGCATGCAATAAATATTTGGCAGGTGAGTGGATGGATAGATGGATAGGTGAATGT
AGGTGGACAGGTGACTGGGTGGATGTTGTGGTCTCTGGAGAAGCACTGCCATTCAGCCTCCTGCTCCAGCTGTTCACATGCAGAAATGCT
CTCTTCACAGGCAGAGAAGCCTGTGGCTAAAGTTTCCACATCCCATTAACTCAGTGCTTTTGTCTTTTTCATGACATGGCACATAGAGAA
AATATTTTTTTCTAGCACACAAGAGCAACCTGAAAGGCTGCTCCTGGCCAGAGGACTCTGTCCCGGGGGACCGTGTCCTCCCCCATGTCC
TGCCTAGGCCCTCAGAGGACCAGGGGATCATGTCTCCAGGTAACCCGACTGTAGCCCCTGCTGGCTGAGCTCCAGCCTGTGCCCACTGAT
AATAGCAGGGACGGCCTTTTCTCTTAGAGCAGCTGATAAGTTTCCCTACCTGATGGCCCCCTCTGACATAAACTGCACACCTGGGGTGAT
GGCTTAAAGCCAGAAAGAGCTGAGGGAGTTAAGAGGGCCAACCTTAGGGCACGTGGGCATTATTAAAGGTCTTAAAAGCATTGAAGATTT

>73824_73824_2_RGS3-BSPRY_RGS3_chr9_116346707_ENST00000350696_BSPRY_chr9_116116520_ENST00000374183_length(amino acids)=1340AA_BP=1
MPVIPALWEVEMGRSQGQEIETILANRSHSDSTPLPNFLSGSHRPECCTCRLLTASGAQDSLPFGRRLYSGPWRSCEEVCHVSVLSVLST
SCGLSLSLPIFPGWMEWLSPDIALPRRDEWTQTSPARKRITHAKVQGAGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLIP
EDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLK
VARRRLRPLRDPLLRMPGGGDTENGKKLKITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHE
IRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARPEQRHSCHLVCDSSDGLLLGGWERYTEVAKRGG
QHTLPALSRATAPTDPNYIILAPLNPGSQLLRPVYQEDTIPEESGSPSKGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVRPHATHSSY
GTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLFTKEDEPGRCDVLRNPLYLQSVKLQEGSSEDLK
FCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAASPPDSKMFETEADEKREMALEEGKGPGAEDSPPSKEPSPGQELPPGQ
DLPPNKDSPSGQEPAPSQEPLSSKDSATSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRD
LPPCQDLPPSQVSLPAKALTEDTMSSGDLLAATGDPPAAPRPAFVIPEVRLDSTYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDE
DTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNG
GSMHHLSLFFTGHRKNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEERAHQS
ILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDI
RIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNA

--------------------------------------------------------------
>73824_73824_3_RGS3-BSPRY_RGS3_chr9_116346707_ENST00000374134_BSPRY_chr9_116116520_ENST00000374183_length(transcript)=3594nt_BP=1495nt
TTCTCGGCTGATCTCTCTGGGTAGGTGCCCTCTGGGGGCAGTACCCCTGCCTGAGTGGCACTTCCCCTCCTGGCTTTGTTTGGTTTGGCC
TCGATTTAGAACAGGGTTGGCAGAGGCAGGCTGACTTGCATTTCTGGTTTTGGGTTTGTTGCTGCACTTTCCCCAAGGGGTGGGCGGGCT
CTGACTGACAGTCACCACTGGGACAGGCCTGGGCCCCACCCTCACCACCCAGGAAAGGGGAAATGCGGCCCGCTCCCCACTCAGTGCCAC
TCTGTGCCACTCCGTGCCAGGCCCTGAGGGCACCCGGTTGCTGCTTCCTTCCGTCTTTCCCCAAGGACTATCAGAGATGCCAGCGTGACC
CCTGACACGTGTGTGCAGCAGCCTGCAGCTGCCCCAAGCCATGGCTGAACACTGACTCCCAGCTGTGGGGCTTCACCATTACAGACTCCC
CAGGGCTTCAAAGACTTCTCAGCTTCGAGCATGGCTTTTGGCTGTCAGGGCAGCTGTACAATAGTGGATGTTTGAGACGGAGGCAGATGA
GAAGAGGGAGATGGCCTTGGAGGAAGGGAAGGGGCCTGGTGCCGAGGATTCCCCACCCAGCAAGGAGCCCTCTCCTGGCCAGGAGCTTCC
TCCAGGACAAGACCTTCCACCCAACAAGGACTCCCCTTCTGGGCAGGAACCCGCTCCCAGCCAAGAACCACTGTCCAGCAAAGACTCAGC
TACCTCTGAAGGATCCCCTCCAGGCCCAGATGCTCCGCCCAGCAAGGATGTGCCACCATGCCAGGAACCCCCTCCAGCCCAAGACCTCTC
ACCCTGCCAGGACCTACCTGCTGGTCAAGAACCCCTGCCTCACCAGGACCCTCTACTCACCAAAGACCTCCCTGCCATCCAGGAATCCCC
CACCCGGGACCTTCCACCCTGTCAAGATCTGCCTCCTAGCCAGGTCTCCCTGCCAGCCAAGGCCCTTACTGAGGACACCATGAGCTCCGG
GGACCTACTAGCAGCTACTGGGGACCCACCTGCGGCCCCCAGGCCAGCCTTCGTGATCCCTGAGGTCCGGCTGGATAGCACCTACAGCCA
GAAGGCAGGGGCAGAGCAGGGCTGCTCGGGAGATGAGGAGGATGCAGAAGAGGCCGAGGAGGTGGAGGAGGGGGAGGAAGGGGAGGAGGA
CGAGGATGAGGACACCAGCGATGACAACTACGGAGAGCGCAGTGAGGCCAAGCGCAGCAGCATGATCGAGACGGGCCAGGGGGCTGAGGG
TGGCCTCTCACTGCGTGTGCAGAACTCGCTGCGGCGCCGGACGCACAGCGAGGGCAGCCTGCTGCAGGAGCCCCGAGGGCCCTGCTTTGC
CTCCGACACCACCTTGCACTGCTCAGACGGTGAGGGCGCCGCCTCCACCTGGGGCATGCCTTCGCCCAGCACCCTCAAGAAAGAGCTGGG
CCGCAATGGTGGCTCCATGCACCACCTTTCCCTCTTCTTCACAGGACACAGGAAGAACAAGATTGTGGACCAGTGTGAGAGGCTGCAGTT
ACAGAGTGCTGCCATCACCAAGTATGTGGCGGACGTCCTGCCGGGGAAGAATCAAAGAGCAGTGAGCATGGCCAGTGCAGCGAGGGAACT
GGTTATCCAGCGGTTGAGTCTGGTGAGGAGTCTTTGCGAGAGCGAGGAGCAGCGGTTACTGGAACAGGTGCATGGCGAAGAGGAGCGGGC
CCACCAGAGCATCCTGACACAGCGGGTGCACTGGGCCGAGGCGCTGCAGAAACTTGACACCATCCGCACTGGCCTGGTGGGCATGCTTAC
TCACCTGGATGACCTCCAGCTGATTCAGAAGGAGCAAGAGATTTTCGAGAGGACCGAAGAAGCAGAGGGCATTTTGGATCCCCAGGAGTC
GGAAATGTTAAACTTTAATGAGAAGTGCACTCGGAGCCCACTACTGACCCAACTCTGGGCAACGGCGGTTCTTGGGTCTCTCTCAGGCAC
AGAGGACATACGGATCGATGAGAGGACAGTCAGCCCCTTCCTGCAATTGTCAGATGATCGAAAGACCCTGACCTTCAGCACCAAGAAGTC
AAAGGCCTGTGCAGATGGCCCGGAGCGCTTCGACCACTGGCCCAATGCCCTGGCTGCCACCTCCTTCCAGAATGGGCTCCATGCCTGGAT
GGTGAATGTCCAGAACAGTTGTGCCTATAAGGTGGGCGTGGCTTCAGGCCACCTGCCCCGCAAGGGTTCTGGCAGTGACTGCCGTCTGGG
CCACAATGCCTTCTCCTGGGTCTTCTCTCGCTATGATCAGGAGTTTCGTTTCTCACACAATGGGCAGCACGAGCCCCTGGGGCTGCTGCG
GGGCCCAGCCCAGCTGGGTGTAGTGCTGGACTTGCAGGTTCAGGAGCTGCTCTTCTATGAGCCAGCCTCCGGCACAGTGCTCTGTGCCCA
TCATGTGTCCTTCCCGGGGCCCCTCTTCCCAGTCTTTGCTGTGGCCGATCAGACCATTTCTATCGTCCGCTGACCTCTGGCCACAGGAAG
CCAGGTCCACCGCCCACCACCCTTTCAGGCCATGTTTCTACTCAGTGTGCTTTTCCCAAATGATGTGTGTGGTGTTTCTAAGAGAAACAG
GGCCCATAACCAGTGGGCAGCTTTAGGAGGGATGGGGATCTGTTTCAGATCTAGGCATAACCTGTAAATCACAGGTGTCCAAACTTTTGG
CTTCCCTGGGCCACATTTGAAGAAGAATTTTCTTGGGCCACATAAAATACACTAACGATAGCTGATGAGCTAAAAAAAAAAAAAAAGTCT
GTGTATAATTTTTGTGATATCTGCCACCACAGATAAGCAAAAAAGTCCTTGCATTCAAAGGGTTGGAGATTGCTGCTTTGAGTGCTGGGT
ACCTGTGGGGAACCTACTACTCCCTGGGCCTTAGTCTCCCAAATCCACCATGCATCTGCCCCTCTGAGGGTGTCTTCACTTTGTCTCTGG
CATCTAGCATGGTGCCTGGTGCATAGTGAGCATGCAATAAATATTTGGCAGGTGAGTGGATGGATAGATGGATAGGTGAATGTAGGTGGA
CAGGTGACTGGGTGGATGTTGTGGTCTCTGGAGAAGCACTGCCATTCAGCCTCCTGCTCCAGCTGTTCACATGCAGAAATGCTCTCTTCA
CAGGCAGAGAAGCCTGTGGCTAAAGTTTCCACATCCCATTAACTCAGTGCTTTTGTCTTTTTCATGACATGGCACATAGAGAAAATATTT
TTTTCTAGCACACAAGAGCAACCTGAAAGGCTGCTCCTGGCCAGAGGACTCTGTCCCGGGGGACCGTGTCCTCCCCCATGTCCTGCCTAG
GCCCTCAGAGGACCAGGGGATCATGTCTCCAGGTAACCCGACTGTAGCCCCTGCTGGCTGAGCTCCAGCCTGTGCCCACTGATAATAGCA
GGGACGGCCTTTTCTCTTAGAGCAGCTGATAAGTTTCCCTACCTGATGGCCCCCTCTGACATAAACTGCACACCTGGGGTGATGGCTTAA

>73824_73824_3_RGS3-BSPRY_RGS3_chr9_116346707_ENST00000374134_BSPRY_chr9_116116520_ENST00000374183_length(amino acids)=661AA_BP=326
MFETEADEKREMALEEGKGPGAEDSPPSKEPSPGQELPPGQDLPPNKDSPSGQEPAPSQEPLSSKDSATSEGSPPGPDAPPSKDVPPCQE
PPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRDLPPCQDLPPSQVSLPAKALTEDTMSSGDLLAATGDPPAAPRPAFVIPEV
RLDSTYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRTHSEGSLLQ
EPRGPCFASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSMHHLSLFFTGHRKNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVS
MASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAE
GILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSF
QNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPA

--------------------------------------------------------------
>73824_73824_4_RGS3-BSPRY_RGS3_chr9_116346707_ENST00000374140_BSPRY_chr9_116116520_ENST00000374183_length(transcript)=5323nt_BP=3224nt
AACTTTGGCTCAGCCTGTCTTCATCCACTGTATCCTGACACCTCTCCTACTCCTTCTCTTTAATGTACAGCTGAGACTGGGATACCCTTA
GACTGAAAGGAAGGACACGGCTATGTAGAAAAGAATTGACTGAAGGGGAGGAGTACTCGTGAACCCCTTGCTTCAGCCTCCCAATGTTCT
GAGAGAGGAGGAGCCAGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGTTGAGATGGGCAGATCGCAAGGTCAGGAGATCG
AGACCATCCTGGCTAACAGGTCACATTCAGACAGCACACCTTTGCCCAATTTTCTTTCTGGATCTCACCGTCCTGAGTGTTGTACCTGCA
GGTTGCTCACAGCCTCTGGAGCCCAAGATAGTCTCCCCTTTGGGAGGAGGCTCTACAGTGGTCCCTGGCGAAGTTGTGAAGAGGTCTGCC
ACGTCTCTGTGCTCAGTGTCCTCTCTACATCCTGTGGCTTGAGCCTGAGCTTGCCCATATTCCCTGGCTGGATGGAGTGGCTAAGCCCTG
ATATCGCTCTGCCCAGAAGAGATGAGTGGACTCAAACTTCTCCAGCCAGGAAGAGGATCACGCATGCCAAAGTCCAGGGTGCAGGTCAGC
TGAGGCTGTCCATTGATGCCCAGGACCGGGTTCTGCTGCTTCACATTATAGAAGGTAAAGGCCTGATCAGCAAACAGCCTGGCACCTGTG
ATCCGTATGTGAAGATTTCTTTGATCCCTGAAGATAGTAGACTACGCCACCAGAAGACGCAGACCGTTCCAGACTGCAGAGACCCGGCTT
TCCACGAGCACTTCTTCTTTCCTGTCCAAGAGGAGGATGATCAGAAGCGTCTCTTGGTTACTGTGTGGAACAGGGCCAGCCAGTCCAGAC
AGAGTGGACTCATTGGCTGCATGAGCTTTGGGGTGAAGTCTCTCCTGACTCCAGACAAGGAGATCAGTGGTTGGTACTACCTCCTAGGGG
AGCACCTGGGCCGGACCAAGCACTTGAAGGTGGCCAGGCGGCGACTGCGGCCGCTGAGAGACCCGCTGCTGAGAATGCCAGGAGGTGGGG
ACACTGAGAATGGGAAGAAACTAAAGATCACCATCCCGAGGGGAAAGGACGGCTTTGGCTTCACCATCTGCTGCGACTCTCCAGTTCGAG
TCCAGGCCGTGGATTCCGGGGGTCCGGCGGAACGGGCAGGGCTGCAGCAGCTGGACACGGTGCTGCAGCTGAATGAGAGGCCTGTGGAGC
ACTGGAAATGTGTGGAGCTGGCCCACGAGATCCGGAGCTGCCCCAGTGAGATCATCCTACTCGTGTGGCGCATGGTCCCCCAGGTCAAGC
CAGGACCAGATGGCGGGGTCCTGCGGCGGGCCTCCTGCAAGTCGACACATGACCTCCAGTCACCCCCCAACAAACGGGAGAAGAACTGCA
CCCATGGGGTCCAGGCACGGCCTGAGCAGCGCCACAGCTGCCACCTGGTATGTGACAGCTCTGATGGGCTGCTGCTCGGCGGCTGGGAGC
GCTACACCGAGGTGGCCAAGCGCGGGGGCCAGCACACCCTGCCTGCACTGTCCCGTGCCACTGCCCCCACCGACCCCAACTACATCATCC
TGGCCCCGCTGAATCCTGGGAGCCAGCTGCTCCGGCCTGTGTACCAGGAGGATACCATCCCCGAAGAATCAGGGAGTCCCAGTAAAGGGA
AGTCCTACACAGGCCTGGGGAAGAAGTCCCGGCTGATGAAGACAGTGCAGACCATGAAGGGCCACGGGAACTACCAAAACTGCCCGGTTG
TGAGGCCGCATGCCACGCACTCAAGCTATGGCACCTACGTCACCCTGGCCCCCAAAGTCCTGGTGTTCCCTGTCTTTGTTCAGCCTCTAG
ATCTCTGTAATCCTGCCCGGACCCTCCTGCTGTCAGAGGAGCTGCTGCTGTATGAAGGGAGGAACAAGGCTGCCGAGGTGACACTGTTTG
CCTATTCGGACCTGCTGCTCTTCACCAAGGAGGACGAGCCTGGCCGCTGCGACGTCCTGAGGAACCCCCTCTACCTCCAGAGTGTGAAGC
TGCAGGAAGGTTCTTCAGAAGACCTGAAATTCTGCGTGCTCTATCTAGCAGAGAAGGCAGAGTGCTTATTCACTTTGGAAGCGCACTCGC
AGGAGCAGAAGAAGAGAGTGTGCTGGTGCCTGTCGGAGAACATCGCCAAGCAGCAACAGCTGGCAGCATCACCCCCGGACAGCAAGATGT
TTGAGACGGAGGCAGATGAGAAGAGGGAGATGGCCTTGGAGGAAGGGAAGGGGCCTGGTGCCGAGGATTCCCCACCCAGCAAGGAGCCCT
CTCCTGGCCAGGAGCTTCCTCCAGGACAAGACCTTCCACCCAACAAGGACTCCCCTTCTGGGCAGGAACCCGCTCCCAGCCAAGAACCAC
TGTCCAGCAAAGACTCAGCTACCTCTGAAGGATCCCCTCCAGGCCCAGATGCTCCGCCCAGCAAGGATGTGCCACCATGCCAGGAACCCC
CTCCAGCCCAAGACCTCTCACCCTGCCAGGACCTACCTGCTGGTCAAGAACCCCTGCCTCACCAGGACCCTCTACTCACCAAAGACCTCC
CTGCCATCCAGGAATCCCCCACCCGGGACCTTCCACCCTGTCAAGATCTGCCTCCTAGCCAGGTCTCCCTGCCAGCCAAGGCCCTTACTG
AGGACACCATGAGCTCCGGGGACCTACTAGCAGCTACTGGGGACCCACCTGCGGCCCCCAGGCCAGCCTTCGTGATCCCTGAGGTCCGGC
TGGATAGCACCTACAGCCAGAAGGCAGGGGCAGAGCAGGGCTGCTCGGGAGATGAGGAGGATGCAGAAGAGGCCGAGGAGGTGGAGGAGG
GGGAGGAAGGGGAGGAGGACGAGGATGAGGACACCAGCGATGACAACTACGGAGAGCGCAGTGAGGCCAAGCGCAGCAGCATGATCGAGA
CGGGCCAGGGGGCTGAGGGTGGCCTCTCACTGCGTGTGCAGAACTCGCTGCGGCGCCGGACGCACAGCGAGGGCAGCCTGCTGCAGGAGC
CCCGAGGGCCCTGCTTTGCCTCCGACACCACCTTGCACTGCTCAGACGGTGAGGGCGCCGCCTCCACCTGGGGCATGCCTTCGCCCAGCA
CCCTCAAGAAAGAGCTGGGCCGCAATGGTGGCTCCATGCACCACCTTTCCCTCTTCTTCACAGGACACAGGAAGAACAAGATTGTGGACC
AGTGTGAGAGGCTGCAGTTACAGAGTGCTGCCATCACCAAGTATGTGGCGGACGTCCTGCCGGGGAAGAATCAAAGAGCAGTGAGCATGG
CCAGTGCAGCGAGGGAACTGGTTATCCAGCGGTTGAGTCTGGTGAGGAGTCTTTGCGAGAGCGAGGAGCAGCGGTTACTGGAACAGGTGC
ATGGCGAAGAGGAGCGGGCCCACCAGAGCATCCTGACACAGCGGGTGCACTGGGCCGAGGCGCTGCAGAAACTTGACACCATCCGCACTG
GCCTGGTGGGCATGCTTACTCACCTGGATGACCTCCAGCTGATTCAGAAGGAGCAAGAGATTTTCGAGAGGACCGAAGAAGCAGAGGGCA
TTTTGGATCCCCAGGAGTCGGAAATGTTAAACTTTAATGAGAAGTGCACTCGGAGCCCACTACTGACCCAACTCTGGGCAACGGCGGTTC
TTGGGTCTCTCTCAGGCACAGAGGACATACGGATCGATGAGAGGACAGTCAGCCCCTTCCTGCAATTGTCAGATGATCGAAAGACCCTGA
CCTTCAGCACCAAGAAGTCAAAGGCCTGTGCAGATGGCCCGGAGCGCTTCGACCACTGGCCCAATGCCCTGGCTGCCACCTCCTTCCAGA
ATGGGCTCCATGCCTGGATGGTGAATGTCCAGAACAGTTGTGCCTATAAGGTGGGCGTGGCTTCAGGCCACCTGCCCCGCAAGGGTTCTG
GCAGTGACTGCCGTCTGGGCCACAATGCCTTCTCCTGGGTCTTCTCTCGCTATGATCAGGAGTTTCGTTTCTCACACAATGGGCAGCACG
AGCCCCTGGGGCTGCTGCGGGGCCCAGCCCAGCTGGGTGTAGTGCTGGACTTGCAGGTTCAGGAGCTGCTCTTCTATGAGCCAGCCTCCG
GCACAGTGCTCTGTGCCCATCATGTGTCCTTCCCGGGGCCCCTCTTCCCAGTCTTTGCTGTGGCCGATCAGACCATTTCTATCGTCCGCT
GACCTCTGGCCACAGGAAGCCAGGTCCACCGCCCACCACCCTTTCAGGCCATGTTTCTACTCAGTGTGCTTTTCCCAAATGATGTGTGTG
GTGTTTCTAAGAGAAACAGGGCCCATAACCAGTGGGCAGCTTTAGGAGGGATGGGGATCTGTTTCAGATCTAGGCATAACCTGTAAATCA
CAGGTGTCCAAACTTTTGGCTTCCCTGGGCCACATTTGAAGAAGAATTTTCTTGGGCCACATAAAATACACTAACGATAGCTGATGAGCT
AAAAAAAAAAAAAAAGTCTGTGTATAATTTTTGTGATATCTGCCACCACAGATAAGCAAAAAAGTCCTTGCATTCAAAGGGTTGGAGATT
GCTGCTTTGAGTGCTGGGTACCTGTGGGGAACCTACTACTCCCTGGGCCTTAGTCTCCCAAATCCACCATGCATCTGCCCCTCTGAGGGT
GTCTTCACTTTGTCTCTGGCATCTAGCATGGTGCCTGGTGCATAGTGAGCATGCAATAAATATTTGGCAGGTGAGTGGATGGATAGATGG
ATAGGTGAATGTAGGTGGACAGGTGACTGGGTGGATGTTGTGGTCTCTGGAGAAGCACTGCCATTCAGCCTCCTGCTCCAGCTGTTCACA
TGCAGAAATGCTCTCTTCACAGGCAGAGAAGCCTGTGGCTAAAGTTTCCACATCCCATTAACTCAGTGCTTTTGTCTTTTTCATGACATG
GCACATAGAGAAAATATTTTTTTCTAGCACACAAGAGCAACCTGAAAGGCTGCTCCTGGCCAGAGGACTCTGTCCCGGGGGACCGTGTCC
TCCCCCATGTCCTGCCTAGGCCCTCAGAGGACCAGGGGATCATGTCTCCAGGTAACCCGACTGTAGCCCCTGCTGGCTGAGCTCCAGCCT
GTGCCCACTGATAATAGCAGGGACGGCCTTTTCTCTTAGAGCAGCTGATAAGTTTCCCTACCTGATGGCCCCCTCTGACATAAACTGCAC
ACCTGGGGTGATGGCTTAAAGCCAGAAAGAGCTGAGGGAGTTAAGAGGGCCAACCTTAGGGCACGTGGGCATTATTAAAGGTCTTAAAAG

>73824_73824_4_RGS3-BSPRY_RGS3_chr9_116346707_ENST00000374140_BSPRY_chr9_116116520_ENST00000374183_length(amino acids)=1340AA_BP=1
MPVIPALWEVEMGRSQGQEIETILANRSHSDSTPLPNFLSGSHRPECCTCRLLTASGAQDSLPFGRRLYSGPWRSCEEVCHVSVLSVLST
SCGLSLSLPIFPGWMEWLSPDIALPRRDEWTQTSPARKRITHAKVQGAGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLIP
EDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLK
VARRRLRPLRDPLLRMPGGGDTENGKKLKITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHE
IRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARPEQRHSCHLVCDSSDGLLLGGWERYTEVAKRGG
QHTLPALSRATAPTDPNYIILAPLNPGSQLLRPVYQEDTIPEESGSPSKGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVRPHATHSSY
GTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLFTKEDEPGRCDVLRNPLYLQSVKLQEGSSEDLK
FCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAASPPDSKMFETEADEKREMALEEGKGPGAEDSPPSKEPSPGQELPPGQ
DLPPNKDSPSGQEPAPSQEPLSSKDSATSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRD
LPPCQDLPPSQVSLPAKALTEDTMSSGDLLAATGDPPAAPRPAFVIPEVRLDSTYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDE
DTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNG
GSMHHLSLFFTGHRKNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEERAHQS
ILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDI
RIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNA

--------------------------------------------------------------
>73824_73824_5_RGS3-BSPRY_RGS3_chr9_116346707_ENST00000462143_BSPRY_chr9_116116520_ENST00000374183_length(transcript)=3492nt_BP=1393nt
ATCGGCTCTGTCCTGCTCTCCACAGGCCTCTGCTGTGTTGGGAGCCACTGCCTTCCTCCCCTCCCCCAACCTGTGGGCCCACAGCTCGCC
AGCTGGCCCTTGAACCCACTTCCCTGCGCCTCTGGCTGCCTCAATGTCACTGGGGATTAGTGTGCATTTGCGGCTTTTGGCGGACACTCC
CCTCCTGGCTGCAGCCTCACCCTCTGGAGCCCAGGGATGGGCTTGGGCCTGGGAGCCCCCTGAACCAGGGAGCAGCCCTGACCGTCCGTT
TCTCTATTTTCCCTGACGTCAGAAGGCAGAGTGCTTATTCACTTTGGAAGCGCACTCGCAGGAGCAGAAGAAGAGAGTGTGCTGGTGCCT
GTCGGAGAACATCGCCAAGCAGCAACAGCTGGCAGCATCACCCCCGGACAGCAAGATGTTTGAGACGGAGGCAGATGAGAAGAGGGAGAT
GGCCTTGGAGGAAGGGAAGGGGCCTGGTGCCGAGGATTCCCCACCCAGCAAGGAGCCCTCTCCTGGCCAGGAGCTTCCTCCAGGACAAGA
CCTTCCACCCAACAAGGACTCCCCTTCTGGGCAGGAACCCGCTCCCAGCCAAGAACCACTGTCCAGCAAAGACTCAGCTACCTCTGAAGG
ATCCCCTCCAGGCCCAGATGCTCCGCCCAGCAAGGATGTGCCACCATGCCAGGAACCCCCTCCAGCCCAAGACCTCTCACCCTGCCAGGA
CCTACCTGCTGGTCAAGAACCCCTGCCTCACCAGGACCCTCTACTCACCAAAGACCTCCCTGCCATCCAGGAATCCCCCACCCGGGACCT
TCCACCCTGTCAAGATCTGCCTCCTAGCCAGGTCTCCCTGCCAGCCAAGGCCCTTACTGAGGACACCATGAGCTCCGGGGACCTACTAGC
AGCTACTGGGGACCCACCTGCGGCCCCCAGGCCAGCCTTCGTGATCCCTGAGGTCCGGCTGGATAGCACCTACAGCCAGAAGGCAGGGGC
AGAGCAGGGCTGCTCGGGAGATGAGGAGGATGCAGAAGAGGCCGAGGAGGTGGAGGAGGGGGAGGAAGGGGAGGAGGACGAGGATGAGGA
CACCAGCGATGACAACTACGGAGAGCGCAGTGAGGCCAAGCGCAGCAGCATGATCGAGACGGGCCAGGGGGCTGAGGGTGGCCTCTCACT
GCGTGTGCAGAACTCGCTGCGGCGCCGGACGCACAGCGAGGGCAGCCTGCTGCAGGAGCCCCGAGGGCCCTGCTTTGCCTCCGACACCAC
CTTGCACTGCTCAGACGGTGAGGGCGCCGCCTCCACCTGGGGCATGCCTTCGCCCAGCACCCTCAAGAAAGAGCTGGGCCGCAATGGTGG
CTCCATGCACCACCTTTCCCTCTTCTTCACAGGACACAGGAAGAACAAGATTGTGGACCAGTGTGAGAGGCTGCAGTTACAGAGTGCTGC
CATCACCAAGTATGTGGCGGACGTCCTGCCGGGGAAGAATCAAAGAGCAGTGAGCATGGCCAGTGCAGCGAGGGAACTGGTTATCCAGCG
GTTGAGTCTGGTGAGGAGTCTTTGCGAGAGCGAGGAGCAGCGGTTACTGGAACAGGTGCATGGCGAAGAGGAGCGGGCCCACCAGAGCAT
CCTGACACAGCGGGTGCACTGGGCCGAGGCGCTGCAGAAACTTGACACCATCCGCACTGGCCTGGTGGGCATGCTTACTCACCTGGATGA
CCTCCAGCTGATTCAGAAGGAGCAAGAGATTTTCGAGAGGACCGAAGAAGCAGAGGGCATTTTGGATCCCCAGGAGTCGGAAATGTTAAA
CTTTAATGAGAAGTGCACTCGGAGCCCACTACTGACCCAACTCTGGGCAACGGCGGTTCTTGGGTCTCTCTCAGGCACAGAGGACATACG
GATCGATGAGAGGACAGTCAGCCCCTTCCTGCAATTGTCAGATGATCGAAAGACCCTGACCTTCAGCACCAAGAAGTCAAAGGCCTGTGC
AGATGGCCCGGAGCGCTTCGACCACTGGCCCAATGCCCTGGCTGCCACCTCCTTCCAGAATGGGCTCCATGCCTGGATGGTGAATGTCCA
GAACAGTTGTGCCTATAAGGTGGGCGTGGCTTCAGGCCACCTGCCCCGCAAGGGTTCTGGCAGTGACTGCCGTCTGGGCCACAATGCCTT
CTCCTGGGTCTTCTCTCGCTATGATCAGGAGTTTCGTTTCTCACACAATGGGCAGCACGAGCCCCTGGGGCTGCTGCGGGGCCCAGCCCA
GCTGGGTGTAGTGCTGGACTTGCAGGTTCAGGAGCTGCTCTTCTATGAGCCAGCCTCCGGCACAGTGCTCTGTGCCCATCATGTGTCCTT
CCCGGGGCCCCTCTTCCCAGTCTTTGCTGTGGCCGATCAGACCATTTCTATCGTCCGCTGACCTCTGGCCACAGGAAGCCAGGTCCACCG
CCCACCACCCTTTCAGGCCATGTTTCTACTCAGTGTGCTTTTCCCAAATGATGTGTGTGGTGTTTCTAAGAGAAACAGGGCCCATAACCA
GTGGGCAGCTTTAGGAGGGATGGGGATCTGTTTCAGATCTAGGCATAACCTGTAAATCACAGGTGTCCAAACTTTTGGCTTCCCTGGGCC
ACATTTGAAGAAGAATTTTCTTGGGCCACATAAAATACACTAACGATAGCTGATGAGCTAAAAAAAAAAAAAAAGTCTGTGTATAATTTT
TGTGATATCTGCCACCACAGATAAGCAAAAAAGTCCTTGCATTCAAAGGGTTGGAGATTGCTGCTTTGAGTGCTGGGTACCTGTGGGGAA
CCTACTACTCCCTGGGCCTTAGTCTCCCAAATCCACCATGCATCTGCCCCTCTGAGGGTGTCTTCACTTTGTCTCTGGCATCTAGCATGG
TGCCTGGTGCATAGTGAGCATGCAATAAATATTTGGCAGGTGAGTGGATGGATAGATGGATAGGTGAATGTAGGTGGACAGGTGACTGGG
TGGATGTTGTGGTCTCTGGAGAAGCACTGCCATTCAGCCTCCTGCTCCAGCTGTTCACATGCAGAAATGCTCTCTTCACAGGCAGAGAAG
CCTGTGGCTAAAGTTTCCACATCCCATTAACTCAGTGCTTTTGTCTTTTTCATGACATGGCACATAGAGAAAATATTTTTTTCTAGCACA
CAAGAGCAACCTGAAAGGCTGCTCCTGGCCAGAGGACTCTGTCCCGGGGGACCGTGTCCTCCCCCATGTCCTGCCTAGGCCCTCAGAGGA
CCAGGGGATCATGTCTCCAGGTAACCCGACTGTAGCCCCTGCTGGCTGAGCTCCAGCCTGTGCCCACTGATAATAGCAGGGACGGCCTTT
TCTCTTAGAGCAGCTGATAAGTTTCCCTACCTGATGGCCCCCTCTGACATAAACTGCACACCTGGGGTGATGGCTTAAAGCCAGAAAGAG

>73824_73824_5_RGS3-BSPRY_RGS3_chr9_116346707_ENST00000462143_BSPRY_chr9_116116520_ENST00000374183_length(amino acids)=695AA_BP=360
MEAHSQEQKKRVCWCLSENIAKQQQLAASPPDSKMFETEADEKREMALEEGKGPGAEDSPPSKEPSPGQELPPGQDLPPNKDSPSGQEPA
PSQEPLSSKDSATSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRDLPPCQDLPPSQVSLP
AKALTEDTMSSGDLLAATGDPPAAPRPAFVIPEVRLDSTYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDNYGERSEAKR
SSMIETGQGAEGGLSLRVQNSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSMHHLSLFFTGHRK
NKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKL
DTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQLSD
DRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for RGS3-BSPRY

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for RGS3-BSPRY

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for RGS3-BSPRY

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source