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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ATF2-CHN1 (FusionGDB2 ID:7408)

Fusion Gene Summary for ATF2-CHN1

check button Fusion gene summary
Fusion gene informationFusion gene name: ATF2-CHN1
Fusion gene ID: 7408
HgeneTgene
Gene symbol

ATF2

CHN1

Gene ID

2668

1959

Gene nameglial cell derived neurotrophic factorearly growth response 2
SynonymsATF|ATF1|ATF2|HFB1-GDNF|HSCR3AT591|CHN1|CMT1D|CMT4E|KROX20
Cytomap

5p13.2

10q21.3

Type of geneprotein-codingprotein-coding
Descriptionglial cell line-derived neurotrophic factorastrocyte-derived trophic factorE3 SUMO-protein ligase EGR2E3 SUMO-protein transferase ERG2KROX-20, Drosophila, homolog (early growth response-2)early growth response protein 2zinc finger protein Krox-20
Modification date2020031420200328
UniProtAcc

P15336

P15882

Ensembl transtripts involved in fusion geneENST00000487334, ENST00000538946, 
ENST00000264110, ENST00000345739, 
ENST00000392543, ENST00000392544, 
ENST00000409437, ENST00000409499, 
ENST00000409635, ENST00000426833, 
ENST00000409833, ENST00000413123, 
ENST00000409900, ENST00000409156, 
ENST00000488080, ENST00000295497, 
ENST00000409597, 
Fusion gene scores* DoF score12 X 11 X 9=11889 X 8 X 6=432
# samples 138
** MAII scorelog2(13/1188*10)=-3.19195130777231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/432*10)=-2.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATF2 [Title/Abstract] AND CHN1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATF2(175945388)-CHN1(175816930), # samples:5
Anticipated loss of major functional domain due to fusion event.ATF2-CHN1 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
ATF2-CHN1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneATF2

GO:0001755

neural crest cell migration

15242795

HgeneATF2

GO:0008284

positive regulation of cell proliferation

22897442

HgeneATF2

GO:0031175

neuron projection development

15242795

HgeneATF2

GO:0032770

positive regulation of monooxygenase activity

12358785

HgeneATF2

GO:0043524

negative regulation of neuron apoptotic process

8493557

HgeneATF2

GO:0045944

positive regulation of transcription by RNA polymerase II

12358785

HgeneATF2

GO:0048255

mRNA stabilization

12358785

HgeneATF2

GO:0051584

regulation of dopamine uptake involved in synaptic transmission

8493557

HgeneATF2

GO:0072107

positive regulation of ureteric bud formation

8657307

HgeneATF2

GO:0090190

positive regulation of branching involved in ureteric bud morphogenesis

8657307|17229286

HgeneATF2

GO:2001240

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

10921886

TgeneCHN1

GO:0045944

positive regulation of transcription by RNA polymerase II

12687019


check buttonFusion gene breakpoints across ATF2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CHN1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-BH-A1ET-11BATF2chr2

175945388

-CHN1chr2

175816930

-
ChimerDB4Non-CancerTCGA-E9-A1N6-11AATF2chr2

175945388

-CHN1chr2

175816930

-
ChimerDB4Non-CancerTCGA-E9-A1NG-11AATF2chr2

175945388

-CHN1chr2

175816930

-
ChimerDB4Non-CancerTCGA-GI-A2C9-11AATF2chr2

175945388

-CHN1chr2

175816930

-
ChimerDB4Non-CancerTCGA-KN-8428-11AATF2chr2

175945388

-CHN1chr2

175816930

-


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Fusion Gene ORF analysis for ATF2-CHN1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000487334ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
3UTR-3CDSENST00000538946ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
3UTR-5UTRENST00000487334ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
3UTR-5UTRENST00000487334ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
3UTR-5UTRENST00000538946ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
3UTR-5UTRENST00000538946ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
3UTR-intronENST00000487334ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
3UTR-intronENST00000487334ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-
3UTR-intronENST00000538946ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
3UTR-intronENST00000538946ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000264110ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000264110ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000345739ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000345739ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000392543ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000392543ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000392544ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000392544ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000409437ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000409437ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000409499ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000409499ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000409635ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000409635ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000426833ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-5UTRENST00000426833ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000264110ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000264110ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000345739ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000345739ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000392543ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000392543ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000392544ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000392544ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000409437ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000409437ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000409499ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000409499ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000409635ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000409635ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000426833ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
5CDS-intronENST00000426833ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-
Frame-shiftENST00000392544ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
Frame-shiftENST00000409437ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
Frame-shiftENST00000426833ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
In-frameENST00000264110ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
In-frameENST00000345739ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
In-frameENST00000392543ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
In-frameENST00000409499ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
In-frameENST00000409635ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
intron-3CDSENST00000409833ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
intron-3CDSENST00000413123ENST00000409900ATF2chr2

175945388

-CHN1chr2

175816930

-
intron-5UTRENST00000409833ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
intron-5UTRENST00000409833ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
intron-5UTRENST00000413123ENST00000409156ATF2chr2

175945388

-CHN1chr2

175816930

-
intron-5UTRENST00000413123ENST00000488080ATF2chr2

175945388

-CHN1chr2

175816930

-
intron-intronENST00000409833ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
intron-intronENST00000409833ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-
intron-intronENST00000413123ENST00000295497ATF2chr2

175945388

-CHN1chr2

175816930

-
intron-intronENST00000413123ENST00000409597ATF2chr2

175945388

-CHN1chr2

175816930

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000345739ATF2chr2175945388-ENST00000409900CHN1chr2175816930-360714933762853825
ENST00000264110ATF2chr2175945388-ENST00000409900CHN1chr2175816930-370415902992950883
ENST00000409635ATF2chr2175945388-ENST00000409900CHN1chr2175816930-366715534362913825
ENST00000392543ATF2chr2175945388-ENST00000409900CHN1chr2175816930-25844702621830522
ENST00000409499ATF2chr2175945388-ENST00000409900CHN1chr2175816930-25844702621830522

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000345739ENST00000409900ATF2chr2175945388-CHN1chr2175816930-0.0008919010.99910814
ENST00000264110ENST00000409900ATF2chr2175945388-CHN1chr2175816930-0.0004842280.9995158
ENST00000409635ENST00000409900ATF2chr2175945388-CHN1chr2175816930-0.0009166330.9990834
ENST00000392543ENST00000409900ATF2chr2175945388-CHN1chr2175816930-0.0002887440.9997112
ENST00000409499ENST00000409900ATF2chr2175945388-CHN1chr2175816930-0.0002887440.9997112

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Fusion Genomic Features for ATF2-CHN1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ATF2-CHN1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:175945388/chr2:175816930)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATF2

P15336

CHN1

P15882

FUNCTION: Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'). In the nucleus, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, proliferation and death. In the cytoplasm, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, thereby impairing mitochondrial membrane potential, inducing mitochondrial leakage and promoting cell death. The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF). Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro (PubMed:10821277). In concert with CUL3 and RBX1, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM. Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type. {ECO:0000269|PubMed:10821277, ECO:0000269|PubMed:15916964, ECO:0000269|PubMed:18397884, ECO:0000269|PubMed:22304920}.FUNCTION: GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATF2chr2:175945388chr2:175816930ENST00000264110-1314352_415430506.0DomainbZIP
HgeneATF2chr2:175945388chr2:175816930ENST00000392544-1415352_415430506.0DomainbZIP
HgeneATF2chr2:175945388chr2:175816930ENST00000426833-1415352_415412488.0DomainbZIP
HgeneATF2chr2:175945388chr2:175816930ENST00000487334-1416352_415398373.3333333333333DomainbZIP
HgeneATF2chr2:175945388chr2:175816930ENST00000264110-13141_7430506.0MotifNote=Nuclear export signal 1 (N-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000264110-1314405_414430506.0MotifNote=Nuclear export signal 2 (C-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000345739-12131_7372448.0MotifNote=Nuclear export signal 1 (N-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000392543-561_751127.0MotifNote=Nuclear export signal 1 (N-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000392544-14151_7430506.0MotifNote=Nuclear export signal 1 (N-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000392544-1415405_414430506.0MotifNote=Nuclear export signal 2 (C-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000409499-561_769145.0MotifNote=Nuclear export signal 1 (N-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000409635-13141_7372448.0MotifNote=Nuclear export signal 1 (N-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000426833-14151_7412488.0MotifNote=Nuclear export signal 1 (N-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000426833-1415405_414412488.0MotifNote=Nuclear export signal 2 (C-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000487334-14161_7398373.3333333333333MotifNote=Nuclear export signal 1 (N-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000487334-1416405_414398373.3333333333333MotifNote=Nuclear export signal 2 (C-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000264110-1314296_299430506.0RegionNote=Essential for its histone acetyltransferase activity
HgeneATF2chr2:175945388chr2:175816930ENST00000264110-1314354_374430506.0RegionBasic motif
HgeneATF2chr2:175945388chr2:175816930ENST00000264110-1314380_408430506.0RegionLeucine-zipper
HgeneATF2chr2:175945388chr2:175816930ENST00000345739-1213296_299372448.0RegionNote=Essential for its histone acetyltransferase activity
HgeneATF2chr2:175945388chr2:175816930ENST00000345739-1213354_374372448.0RegionBasic motif
HgeneATF2chr2:175945388chr2:175816930ENST00000392544-1415296_299430506.0RegionNote=Essential for its histone acetyltransferase activity
HgeneATF2chr2:175945388chr2:175816930ENST00000392544-1415354_374430506.0RegionBasic motif
HgeneATF2chr2:175945388chr2:175816930ENST00000392544-1415380_408430506.0RegionLeucine-zipper
HgeneATF2chr2:175945388chr2:175816930ENST00000409635-1314296_299372448.0RegionNote=Essential for its histone acetyltransferase activity
HgeneATF2chr2:175945388chr2:175816930ENST00000409635-1314354_374372448.0RegionBasic motif
HgeneATF2chr2:175945388chr2:175816930ENST00000426833-1415296_299412488.0RegionNote=Essential for its histone acetyltransferase activity
HgeneATF2chr2:175945388chr2:175816930ENST00000426833-1415354_374412488.0RegionBasic motif
HgeneATF2chr2:175945388chr2:175816930ENST00000426833-1415380_408412488.0RegionLeucine-zipper
HgeneATF2chr2:175945388chr2:175816930ENST00000487334-1416296_299398373.3333333333333RegionNote=Essential for its histone acetyltransferase activity
HgeneATF2chr2:175945388chr2:175816930ENST00000487334-1416354_374398373.3333333333333RegionBasic motif
HgeneATF2chr2:175945388chr2:175816930ENST00000487334-1416380_408398373.3333333333333RegionLeucine-zipper
HgeneATF2chr2:175945388chr2:175816930ENST00000264110-131425_49430506.0Zinc fingerC2H2-type
HgeneATF2chr2:175945388chr2:175816930ENST00000345739-121325_49372448.0Zinc fingerC2H2-type
HgeneATF2chr2:175945388chr2:175816930ENST00000392543-5625_4951127.0Zinc fingerC2H2-type
HgeneATF2chr2:175945388chr2:175816930ENST00000392544-141525_49430506.0Zinc fingerC2H2-type
HgeneATF2chr2:175945388chr2:175816930ENST00000409499-5625_4969145.0Zinc fingerC2H2-type
HgeneATF2chr2:175945388chr2:175816930ENST00000409635-131425_49372448.0Zinc fingerC2H2-type
HgeneATF2chr2:175945388chr2:175816930ENST00000426833-141525_49412488.0Zinc fingerC2H2-type
HgeneATF2chr2:175945388chr2:175816930ENST00000487334-141625_49398373.3333333333333Zinc fingerC2H2-type
TgeneCHN1chr2:175945388chr2:175816930ENST0000029549707268_4590335.0DomainRho-GAP
TgeneCHN1chr2:175945388chr2:175816930ENST000002954970749_1350335.0DomainSH2
TgeneCHN1chr2:175945388chr2:175816930ENST00000409156113268_4596434.0DomainRho-GAP
TgeneCHN1chr2:175945388chr2:175816930ENST0000040915611349_1356434.0DomainSH2
TgeneCHN1chr2:175945388chr2:175816930ENST00000409900013268_4596460.0DomainRho-GAP
TgeneCHN1chr2:175945388chr2:175816930ENST0000040990001349_1356460.0DomainSH2
TgeneCHN1chr2:175945388chr2:175816930ENST0000029549707205_2550335.0Zinc fingerPhorbol-ester/DAG-type
TgeneCHN1chr2:175945388chr2:175816930ENST00000409156113205_2556434.0Zinc fingerPhorbol-ester/DAG-type
TgeneCHN1chr2:175945388chr2:175816930ENST00000409900013205_2556460.0Zinc fingerPhorbol-ester/DAG-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATF2chr2:175945388chr2:175816930ENST00000345739-1213352_415372448.0DomainbZIP
HgeneATF2chr2:175945388chr2:175816930ENST00000392543-56352_41551127.0DomainbZIP
HgeneATF2chr2:175945388chr2:175816930ENST00000409499-56352_41569145.0DomainbZIP
HgeneATF2chr2:175945388chr2:175816930ENST00000409635-1314352_415372448.0DomainbZIP
HgeneATF2chr2:175945388chr2:175816930ENST00000409833-18352_4150210.0DomainbZIP
HgeneATF2chr2:175945388chr2:175816930ENST00000345739-1213405_414372448.0MotifNote=Nuclear export signal 2 (C-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000392543-56405_41451127.0MotifNote=Nuclear export signal 2 (C-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000409499-56405_41469145.0MotifNote=Nuclear export signal 2 (C-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000409635-1314405_414372448.0MotifNote=Nuclear export signal 2 (C-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000409833-181_70210.0MotifNote=Nuclear export signal 1 (N-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000409833-18405_4140210.0MotifNote=Nuclear export signal 2 (C-NES)
HgeneATF2chr2:175945388chr2:175816930ENST00000345739-1213380_408372448.0RegionLeucine-zipper
HgeneATF2chr2:175945388chr2:175816930ENST00000392543-56296_29951127.0RegionNote=Essential for its histone acetyltransferase activity
HgeneATF2chr2:175945388chr2:175816930ENST00000392543-56354_37451127.0RegionBasic motif
HgeneATF2chr2:175945388chr2:175816930ENST00000392543-56380_40851127.0RegionLeucine-zipper
HgeneATF2chr2:175945388chr2:175816930ENST00000409499-56296_29969145.0RegionNote=Essential for its histone acetyltransferase activity
HgeneATF2chr2:175945388chr2:175816930ENST00000409499-56354_37469145.0RegionBasic motif
HgeneATF2chr2:175945388chr2:175816930ENST00000409499-56380_40869145.0RegionLeucine-zipper
HgeneATF2chr2:175945388chr2:175816930ENST00000409635-1314380_408372448.0RegionLeucine-zipper
HgeneATF2chr2:175945388chr2:175816930ENST00000409833-18296_2990210.0RegionNote=Essential for its histone acetyltransferase activity
HgeneATF2chr2:175945388chr2:175816930ENST00000409833-18354_3740210.0RegionBasic motif
HgeneATF2chr2:175945388chr2:175816930ENST00000409833-18380_4080210.0RegionLeucine-zipper
HgeneATF2chr2:175945388chr2:175816930ENST00000409833-1825_490210.0Zinc fingerC2H2-type


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Fusion Gene Sequence for ATF2-CHN1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>7408_7408_1_ATF2-CHN1_ATF2_chr2_175945388_ENST00000264110_CHN1_chr2_175816930_ENST00000409900_length(transcript)=3704nt_BP=1590nt
GTTGTCAGTCCGATCTCGCGAGAGAGGACGGAAGCCTGTGGGAGCCCGTGGCCTTTAAAGTGCCGTTCAGCCTTTTCCTCCAGGGGTGCT
TTGTAAACACGGCTGTGCTCAGGGCTCGCGGGTGACCGAAAGGATCATGAACTAGTGACCTGGAAAGGGTACTAGATGGAAACTTGAGAA
AGGACTGCTTATTGATAACAGCTAAGGTATTCCTGGAAGCAGAGTAAATAAAGCTCATGGCCCACCAGCTAGAAAGTATTCTTGCCATGA
GAAAAAGAATGTGATAAGTTATTCAACTTATGAAATTCAAGTTACATGTGAATTCTGCCAGGCAATACAAGGACCTGTGGAATATGAGTG
ATGACAAACCCTTTCTATGTACTGCGCCTGGATGTGGCCAGCGTTTTACCAACGAGGATCATTTGGCTGTCCATAAACATAAACATGAGA
TGACACTGAAATTTGGTCCAGCACGTAATGACAGTGTCATTGTGGCTGATCAGACCCCAACACCAACAAGATTCTTGAAAAACTGTGAAG
AAGTGGGTTTGTTTAATGAGTTGGCGAGTCCATTTGAGAATGAATTCAAGAAAGCTTCAGAAGATGACATTAAAAAAATGCCTCTAGATT
TATCCCCTCTTGCAACACCTATCATAAGAAGCAAAATTGAGGAGCCTTCTGTTGTAGAAACAACTCACCAGGATAGTCCTTTACCTCACC
CAGAGTCTACTACCAGTGATGAGAAGGAAGTACCATTGGCACAAACTGCACAGCCCACATCAGCTATTGTTCGTCCAGCATCATTACAGG
TTCCCAATGTGCTGCTTACAAGTTCTGACTCAAGTGTAATTATTCAGCAGGCAGTACCTTCACCAACCTCAAGTACTGTAATCACCCAGG
CACCATCCTCTAACAGGCCAATTGTCCCTGTACCAGGCCCATTTCCTCTTCTGTTACATCTTCCTAATGGACAAACCATGCCTGTTGCTA
TTCCTGCATCAATTACAAGTTCTAATGTGCATGTTCCAGCTGCAGTCCCACTCGTTCGACCAGTCACCATGGTGCCTAGTGTTCCAGGAA
TCCCAGGTCCTTCCTCTCCCCAACCAGTACAGTCAGAAGCAAAAATGAGATTAAAAGCTGCTTTGACCCAGCAACATCCTCCAGTTACCA
ATGGTGATACTGTCAAAGGTCATGGTAGCGGATTGGTTAGGACTCAGTCAGAGGAATCTCGACCGCAGTCATTACAACAGCCAGCCACAT
CCACTACAGAAACTCCGGCTTCTCCAGCTCACACAACTCCACAGACCCAAAGTACAAGTGGTCGTCGGAGAAGAGCAGCTAACGAAGATC
CTGATGAAAAAAGGAGAAAGTTTTTAGAGCGAAATAGAGCAGCAGCTTCAAGATGCCGACAAAAAAGGAAAGTCTGGGTTCAGTCTTTAG
AGAAGAAAGCTGAAGACTTGAGTTCATTAAATGGTCAGCTGCAGAGTGAAGTCACCCTGCTGAGAAATGAAGTGGCACAGCTGAAACAGC
TTCTTCTGGCTCATAAAGATTGCCCTGTAACCGCCATGCAGAAGAAATCTGGCTATCATAATACAGATGAATATAGACCTCCTGTTTGGA
AATCTTACTTATATCAGCTACAACAGGAAGCCCCTCATCCTCGAAGAATTACCTGTACTTGCGAGGTGGAAAACAGACCAAAGTATTATG
GAAGAGAGTTTCATGGCATGATCTCCAGAGAAGCAGCCGACCAGCTCTTGATTGTGGCTGAGGGGAGCTACCTCATCCGGGAGAGCCAGC
GGCAGCCAGGGACCTACACTTTGGCTTTAAGATTTGGAAGTCAAACCAGAAACTTCAGGCTCTACTACGATGGCAAGCACTTTGTTGGGG
AGAAACGCTTTGAGTCCATCCACGATCTGGTGACTGATGGCTTGATTACTCTCTATATTGAAACCAAGGCAGCAGAATACATTGCCAAGA
TGACGATAAACCCAATTTATGAGCACGTAGGATACACAACCTTAAACAGAGAGCCAGCATACAAAAAACATATGCCAGTCCTGAAAGAGA
CACATGATGAGAGAGATTCTACAGGCCAGGATGGGGTGTCAGAGAAAAGGTTGACATCACTTGTTAGAAGAGCAACTCTGAAAGAAAACG
AGCAAATTCCAAAATATGAAAAGATTCACAATTTCAAGGTGCATACATTCAGAGGGCCACACTGGTGTGAATACTGTGCCAACTTTATGT
GGGGTCTCATTGCTCAGGGAGTGAAATGTGCAGATTGTGGTTTGAATGTTCATAAGCAGTGTTCCAAGATGGTCCCAAATGACTGTAAGC
CAGACTTGAAGCATGTCAAAAAGGTGTACAGCTGTGACCTTACGACGCTCGTGAAAGCACATACCACTAAGCGGCCAATGGTGGTAGACA
TGTGCATCAGGGAGATTGAGTCTAGAGGTCTTAATTCTGAAGGACTATACCGAGTATCAGGATTTAGTGACCTAATTGAAGATGTCAAGA
TGGCTTTCGACAGAGATGGTGAGAAGGCAGATATTTCTGTGAACATGTATGAAGATATCAACATTATCACTGGTGCACTTAAACTGTACT
TCAGGGATTTGCCAATTCCACTCATTACATATGATGCCTACCCTAAGTTTATAGAATCTGCCAAAATTATGGATCCGGATGAGCAATTGG
AAACCCTTCATGAAGCACTGAAACTACTGCCACCTGCTCACTGCGAAACCCTCCGGTACCTCATGGCACATCTAAAGAGAGTGACCCTCC
ACGAAAAGGAGAATCTTATGAATGCAGAGAACCTTGGAATCGTCTTTGGACCCACCCTTATGAGATCTCCAGAACTAGACGCCATGGCTG
CATTGAATGATATACGGTATCAGAGACTGGTGGTGGAGCTGCTTATCAAAAACGAAGACATTTTATTTTAAATTTTTAATTTGAGGGGAA
AAGAAATGTTTTACAGATGAAGGAATGTTTTATAGTAATTTAATTTGCTCCTGTAGCTGCATTATTTCTTGATTAGAGGTTTGGGCATAT
AACCAGATTAAAGTGAAGGAACTTTCTGTTGTTTTTGTAGCACCGCTCAGCTGTCTTGTAAAACAGTGAACACACGCTTTCTGGTTCTAG
TAATCCTGGGTGTTTATCACGTTCAGAGAAACTCAAGCTATTGCATGATTAGCCCCCTATCTGGCAAGGAAACCCCATACAGAAGAAACA
ACAAACCTGCGCCTGCACCGCCTCTGCGTCCTGGGTAGTCTGTGCTTGTAATCCAGCATGTTTCACAGAGTAAGCCTGTTGTGACTTTGC
TTTTGGGGTCTATGTCATTGGTTTCTGATGCTTGTACAAACACGCACACACAAATGGATAAAACAGCACCTCTGGCTGTTACATTACCAT
AAACCATATCACATGCCTACATTTTACAAATGATTTCTGGTTTCTCTTAGTTCTTCTCTAACATAGTACTTTCTTTCCAGCAAAAGCAAA
ATGTGTTTTCAGATTTGTTACTTTAATAAAGGTTATCCATACCAATAAAAAGTGTACAACACAGCATTTTCTGTTAAATTATTATTGGTT
TTCAGTTGTAATTTGGTATTTTTTCTGGCATGCGTTTATTAATTTATTAAATTGGCTTTTAGAAATAAAAAATATTGATAGCTTACTTTT

>7408_7408_1_ATF2-CHN1_ATF2_chr2_175945388_ENST00000264110_CHN1_chr2_175816930_ENST00000409900_length(amino acids)=883AA_BP=0
MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARNDSVIVADQTPTPTRFLKNCEEVGLFNELAS
PFENEFKKASEDDIKKMPLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSD
SSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNVHVPAAVPLVRPVTMVPSVPGIPGPSSPQPV
QSEAKMRLKAALTQQHPPVTNGDTVKGHGSGLVRTQSEESRPQSLQQPATSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLE
RNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDCPVTAMQKKSGYHNTDEYRPPVWKSYLYQLQQE
APHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDL
VTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIH
NFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRG
LNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLL

--------------------------------------------------------------
>7408_7408_2_ATF2-CHN1_ATF2_chr2_175945388_ENST00000345739_CHN1_chr2_175816930_ENST00000409900_length(transcript)=3607nt_BP=1493nt
GTTGTCAGTCCGATCTCGCGAGAGAGGACGGAAGCCTGTGGGAGCCCGTGGCCTTTAAAGTGCCGTTCAGCCTTTTCCTCCAGGGGTGCT
TTGTAAACACGGCTGTGCTCAGGGCTCGCGGGTGACCGAAAGGATCATGAACTAGTGACCTGGAAAGGGTACTAGATGGAAACTTGAGAA
AGGACTGCTTATTGATAACAGCTAAGGTATTCCTGGAAGCAGAGTAAATAAAGCTCATGGCCCACCAGCTAGAAAGTATTCTTGCCATGA
GAAAAAGAATGTGATAAGTTATTCAACTTATGAAATTCAAGTTACATGTGAATTCTGCCAGGCAATACAAGGACCTGTGGAATATGAGTG
ATGACAAACCCTTTCTATGTACTGCGCCTGGATGTGGCCAGATCAGACCCCAACACCAACAAGATTCTTGAAAAACTGTGAAGAAGTGGG
TTTGTTTAATGAGTTGGCGAGTCCATTTGAGAATGAATTCAAGAAAGCTTCAGAAGATGACATTAAAAAAATGCCTCTAGATTTATCCCC
TCTTGCAACACCTATCATAAGAAGCAAAATTGAGGAGCCTTCTGTTGTAGAAACAACTCACCAGGATAGTCCTTTACCTCACCCAGAGTC
TACTACCAGTGATGAGAAGGAAGTACCATTGGCACAAACTGCACAGCCCACATCAGCTATTGTTCGTCCAGCATCATTACAGGTTCCCAA
TGTGCTGCTTACAAGTTCTGACTCAAGTGTAATTATTCAGCAGGCAGTACCTTCACCAACCTCAAGTACTGTAATCACCCAGGCACCATC
CTCTAACAGGCCAATTGTCCCTGTACCAGGCCCATTTCCTCTTCTGTTACATCTTCCTAATGGACAAACCATGCCTGTTGCTATTCCTGC
ATCAATTACAAGTTCTAATGTGCATGTTCCAGCTGCAGTCCCACTCGTTCGACCAGTCACCATGGTGCCTAGTGTTCCAGGAATCCCAGG
TCCTTCCTCTCCCCAACCAGTACAGTCAGAAGCAAAAATGAGATTAAAAGCTGCTTTGACCCAGCAACATCCTCCAGTTACCAATGGTGA
TACTGTCAAAGGTCATGGTAGCGGATTGGTTAGGACTCAGTCAGAGGAATCTCGACCGCAGTCATTACAACAGCCAGCCACATCCACTAC
AGAAACTCCGGCTTCTCCAGCTCACACAACTCCACAGACCCAAAGTACAAGTGGTCGTCGGAGAAGAGCAGCTAACGAAGATCCTGATGA
AAAAAGGAGAAAGTTTTTAGAGCGAAATAGAGCAGCAGCTTCAAGATGCCGACAAAAAAGGAAAGTCTGGGTTCAGTCTTTAGAGAAGAA
AGCTGAAGACTTGAGTTCATTAAATGGTCAGCTGCAGAGTGAAGTCACCCTGCTGAGAAATGAAGTGGCACAGCTGAAACAGCTTCTTCT
GGCTCATAAAGATTGCCCTGTAACCGCCATGCAGAAGAAATCTGGCTATCATAATACAGATGAATATAGACCTCCTGTTTGGAAATCTTA
CTTATATCAGCTACAACAGGAAGCCCCTCATCCTCGAAGAATTACCTGTACTTGCGAGGTGGAAAACAGACCAAAGTATTATGGAAGAGA
GTTTCATGGCATGATCTCCAGAGAAGCAGCCGACCAGCTCTTGATTGTGGCTGAGGGGAGCTACCTCATCCGGGAGAGCCAGCGGCAGCC
AGGGACCTACACTTTGGCTTTAAGATTTGGAAGTCAAACCAGAAACTTCAGGCTCTACTACGATGGCAAGCACTTTGTTGGGGAGAAACG
CTTTGAGTCCATCCACGATCTGGTGACTGATGGCTTGATTACTCTCTATATTGAAACCAAGGCAGCAGAATACATTGCCAAGATGACGAT
AAACCCAATTTATGAGCACGTAGGATACACAACCTTAAACAGAGAGCCAGCATACAAAAAACATATGCCAGTCCTGAAAGAGACACATGA
TGAGAGAGATTCTACAGGCCAGGATGGGGTGTCAGAGAAAAGGTTGACATCACTTGTTAGAAGAGCAACTCTGAAAGAAAACGAGCAAAT
TCCAAAATATGAAAAGATTCACAATTTCAAGGTGCATACATTCAGAGGGCCACACTGGTGTGAATACTGTGCCAACTTTATGTGGGGTCT
CATTGCTCAGGGAGTGAAATGTGCAGATTGTGGTTTGAATGTTCATAAGCAGTGTTCCAAGATGGTCCCAAATGACTGTAAGCCAGACTT
GAAGCATGTCAAAAAGGTGTACAGCTGTGACCTTACGACGCTCGTGAAAGCACATACCACTAAGCGGCCAATGGTGGTAGACATGTGCAT
CAGGGAGATTGAGTCTAGAGGTCTTAATTCTGAAGGACTATACCGAGTATCAGGATTTAGTGACCTAATTGAAGATGTCAAGATGGCTTT
CGACAGAGATGGTGAGAAGGCAGATATTTCTGTGAACATGTATGAAGATATCAACATTATCACTGGTGCACTTAAACTGTACTTCAGGGA
TTTGCCAATTCCACTCATTACATATGATGCCTACCCTAAGTTTATAGAATCTGCCAAAATTATGGATCCGGATGAGCAATTGGAAACCCT
TCATGAAGCACTGAAACTACTGCCACCTGCTCACTGCGAAACCCTCCGGTACCTCATGGCACATCTAAAGAGAGTGACCCTCCACGAAAA
GGAGAATCTTATGAATGCAGAGAACCTTGGAATCGTCTTTGGACCCACCCTTATGAGATCTCCAGAACTAGACGCCATGGCTGCATTGAA
TGATATACGGTATCAGAGACTGGTGGTGGAGCTGCTTATCAAAAACGAAGACATTTTATTTTAAATTTTTAATTTGAGGGGAAAAGAAAT
GTTTTACAGATGAAGGAATGTTTTATAGTAATTTAATTTGCTCCTGTAGCTGCATTATTTCTTGATTAGAGGTTTGGGCATATAACCAGA
TTAAAGTGAAGGAACTTTCTGTTGTTTTTGTAGCACCGCTCAGCTGTCTTGTAAAACAGTGAACACACGCTTTCTGGTTCTAGTAATCCT
GGGTGTTTATCACGTTCAGAGAAACTCAAGCTATTGCATGATTAGCCCCCTATCTGGCAAGGAAACCCCATACAGAAGAAACAACAAACC
TGCGCCTGCACCGCCTCTGCGTCCTGGGTAGTCTGTGCTTGTAATCCAGCATGTTTCACAGAGTAAGCCTGTTGTGACTTTGCTTTTGGG
GTCTATGTCATTGGTTTCTGATGCTTGTACAAACACGCACACACAAATGGATAAAACAGCACCTCTGGCTGTTACATTACCATAAACCAT
ATCACATGCCTACATTTTACAAATGATTTCTGGTTTCTCTTAGTTCTTCTCTAACATAGTACTTTCTTTCCAGCAAAAGCAAAATGTGTT
TTCAGATTTGTTACTTTAATAAAGGTTATCCATACCAATAAAAAGTGTACAACACAGCATTTTCTGTTAAATTATTATTGGTTTTCAGTT
GTAATTTGGTATTTTTTCTGGCATGCGTTTATTAATTTATTAAATTGGCTTTTAGAAATAAAAAATATTGATAGCTTACTTTTTTCTCAT

>7408_7408_2_ATF2-CHN1_ATF2_chr2_175945388_ENST00000345739_CHN1_chr2_175816930_ENST00000409900_length(amino acids)=825AA_BP=0
MYCAWMWPDQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDE
KEVPLAQTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSS
NVHVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKMRLKAALTQQHPPVTNGDTVKGHGSGLVRTQSEESRPQSLQQPATSTTETPAS
PAHTTPQTQSTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDC
PVTAMQKKSGYHNTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTL
ALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDST
GQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKK
VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPL
ITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQ

--------------------------------------------------------------
>7408_7408_3_ATF2-CHN1_ATF2_chr2_175945388_ENST00000392543_CHN1_chr2_175816930_ENST00000409900_length(transcript)=2584nt_BP=470nt
GTGGGAGCCCGTGGCCTTTAAAGTGCCGTTCAGCCTTTTCCTCCAGGGGTGCTTTGTAAACACGGCTGTGCTCAGGGCTCGCGGGTGACC
GAAAGGATCATGAACTAGTGACCTGGAAAGGGTACTAGATGGAAACTTGAGAAAGGACTGCTTATTGATAACAGCTAAGGTATTCCTGGA
AGCAGAGTAAATAAAGCTCATGGCCCACCAGCTAGAAAGTATTCTTGCCATGAGAAAAAGAATGTGATAAGTTATTCAACTTATGAAATT
CAAGTTACATGTGAATTCTGCCAGGCAATACAAGGACCTGTGGAATATGAGTGATGACAAACCCTTTCTATGTACTGCGCCTGGATGTGG
CCAGAGTGAAGTCACCCTGCTGAGAAATGAAGTGGCACAGCTGAAACAGCTTCTTCTGGCTCATAAAGATTGCCCTGTAACCGCCATGCA
GAAGAAATCTGGCTATCATAATACAGATGAATATAGACCTCCTGTTTGGAAATCTTACTTATATCAGCTACAACAGGAAGCCCCTCATCC
TCGAAGAATTACCTGTACTTGCGAGGTGGAAAACAGACCAAAGTATTATGGAAGAGAGTTTCATGGCATGATCTCCAGAGAAGCAGCCGA
CCAGCTCTTGATTGTGGCTGAGGGGAGCTACCTCATCCGGGAGAGCCAGCGGCAGCCAGGGACCTACACTTTGGCTTTAAGATTTGGAAG
TCAAACCAGAAACTTCAGGCTCTACTACGATGGCAAGCACTTTGTTGGGGAGAAACGCTTTGAGTCCATCCACGATCTGGTGACTGATGG
CTTGATTACTCTCTATATTGAAACCAAGGCAGCAGAATACATTGCCAAGATGACGATAAACCCAATTTATGAGCACGTAGGATACACAAC
CTTAAACAGAGAGCCAGCATACAAAAAACATATGCCAGTCCTGAAAGAGACACATGATGAGAGAGATTCTACAGGCCAGGATGGGGTGTC
AGAGAAAAGGTTGACATCACTTGTTAGAAGAGCAACTCTGAAAGAAAACGAGCAAATTCCAAAATATGAAAAGATTCACAATTTCAAGGT
GCATACATTCAGAGGGCCACACTGGTGTGAATACTGTGCCAACTTTATGTGGGGTCTCATTGCTCAGGGAGTGAAATGTGCAGATTGTGG
TTTGAATGTTCATAAGCAGTGTTCCAAGATGGTCCCAAATGACTGTAAGCCAGACTTGAAGCATGTCAAAAAGGTGTACAGCTGTGACCT
TACGACGCTCGTGAAAGCACATACCACTAAGCGGCCAATGGTGGTAGACATGTGCATCAGGGAGATTGAGTCTAGAGGTCTTAATTCTGA
AGGACTATACCGAGTATCAGGATTTAGTGACCTAATTGAAGATGTCAAGATGGCTTTCGACAGAGATGGTGAGAAGGCAGATATTTCTGT
GAACATGTATGAAGATATCAACATTATCACTGGTGCACTTAAACTGTACTTCAGGGATTTGCCAATTCCACTCATTACATATGATGCCTA
CCCTAAGTTTATAGAATCTGCCAAAATTATGGATCCGGATGAGCAATTGGAAACCCTTCATGAAGCACTGAAACTACTGCCACCTGCTCA
CTGCGAAACCCTCCGGTACCTCATGGCACATCTAAAGAGAGTGACCCTCCACGAAAAGGAGAATCTTATGAATGCAGAGAACCTTGGAAT
CGTCTTTGGACCCACCCTTATGAGATCTCCAGAACTAGACGCCATGGCTGCATTGAATGATATACGGTATCAGAGACTGGTGGTGGAGCT
GCTTATCAAAAACGAAGACATTTTATTTTAAATTTTTAATTTGAGGGGAAAAGAAATGTTTTACAGATGAAGGAATGTTTTATAGTAATT
TAATTTGCTCCTGTAGCTGCATTATTTCTTGATTAGAGGTTTGGGCATATAACCAGATTAAAGTGAAGGAACTTTCTGTTGTTTTTGTAG
CACCGCTCAGCTGTCTTGTAAAACAGTGAACACACGCTTTCTGGTTCTAGTAATCCTGGGTGTTTATCACGTTCAGAGAAACTCAAGCTA
TTGCATGATTAGCCCCCTATCTGGCAAGGAAACCCCATACAGAAGAAACAACAAACCTGCGCCTGCACCGCCTCTGCGTCCTGGGTAGTC
TGTGCTTGTAATCCAGCATGTTTCACAGAGTAAGCCTGTTGTGACTTTGCTTTTGGGGTCTATGTCATTGGTTTCTGATGCTTGTACAAA
CACGCACACACAAATGGATAAAACAGCACCTCTGGCTGTTACATTACCATAAACCATATCACATGCCTACATTTTACAAATGATTTCTGG
TTTCTCTTAGTTCTTCTCTAACATAGTACTTTCTTTCCAGCAAAAGCAAAATGTGTTTTCAGATTTGTTACTTTAATAAAGGTTATCCAT
ACCAATAAAAAGTGTACAACACAGCATTTTCTGTTAAATTATTATTGGTTTTCAGTTGTAATTTGGTATTTTTTCTGGCATGCGTTTATT

>7408_7408_3_ATF2-CHN1_ATF2_chr2_175945388_ENST00000392543_CHN1_chr2_175816930_ENST00000409900_length(amino acids)=522AA_BP=0
MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQSEVTLLRNEVAQLKQLLLAHKDCPVTAMQKKSGYHNTDEYRPPVWKSYLYQLQQEA
PHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLV
TDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHN
FKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGL
NSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLP

--------------------------------------------------------------
>7408_7408_4_ATF2-CHN1_ATF2_chr2_175945388_ENST00000409499_CHN1_chr2_175816930_ENST00000409900_length(transcript)=2584nt_BP=470nt
GTGGGAGCCCGTGGCCTTTAAAGTGCCGTTCAGCCTTTTCCTCCAGGGGTGCTTTGTAAACACGGCTGTGCTCAGGGCTCGCGGGTGACC
GAAAGGATCATGAACTAGTGACCTGGAAAGGGTACTAGATGGAAACTTGAGAAAGGACTGCTTATTGATAACAGCTAAGGTATTCCTGGA
AGCAGAGTAAATAAAGCTCATGGCCCACCAGCTAGAAAGTATTCTTGCCATGAGAAAAAGAATGTGATAAGTTATTCAACTTATGAAATT
CAAGTTACATGTGAATTCTGCCAGGCAATACAAGGACCTGTGGAATATGAGTGATGACAAACCCTTTCTATGTACTGCGCCTGGATGTGG
CCAGAGTGAAGTCACCCTGCTGAGAAATGAAGTGGCACAGCTGAAACAGCTTCTTCTGGCTCATAAAGATTGCCCTGTAACCGCCATGCA
GAAGAAATCTGGCTATCATAATACAGATGAATATAGACCTCCTGTTTGGAAATCTTACTTATATCAGCTACAACAGGAAGCCCCTCATCC
TCGAAGAATTACCTGTACTTGCGAGGTGGAAAACAGACCAAAGTATTATGGAAGAGAGTTTCATGGCATGATCTCCAGAGAAGCAGCCGA
CCAGCTCTTGATTGTGGCTGAGGGGAGCTACCTCATCCGGGAGAGCCAGCGGCAGCCAGGGACCTACACTTTGGCTTTAAGATTTGGAAG
TCAAACCAGAAACTTCAGGCTCTACTACGATGGCAAGCACTTTGTTGGGGAGAAACGCTTTGAGTCCATCCACGATCTGGTGACTGATGG
CTTGATTACTCTCTATATTGAAACCAAGGCAGCAGAATACATTGCCAAGATGACGATAAACCCAATTTATGAGCACGTAGGATACACAAC
CTTAAACAGAGAGCCAGCATACAAAAAACATATGCCAGTCCTGAAAGAGACACATGATGAGAGAGATTCTACAGGCCAGGATGGGGTGTC
AGAGAAAAGGTTGACATCACTTGTTAGAAGAGCAACTCTGAAAGAAAACGAGCAAATTCCAAAATATGAAAAGATTCACAATTTCAAGGT
GCATACATTCAGAGGGCCACACTGGTGTGAATACTGTGCCAACTTTATGTGGGGTCTCATTGCTCAGGGAGTGAAATGTGCAGATTGTGG
TTTGAATGTTCATAAGCAGTGTTCCAAGATGGTCCCAAATGACTGTAAGCCAGACTTGAAGCATGTCAAAAAGGTGTACAGCTGTGACCT
TACGACGCTCGTGAAAGCACATACCACTAAGCGGCCAATGGTGGTAGACATGTGCATCAGGGAGATTGAGTCTAGAGGTCTTAATTCTGA
AGGACTATACCGAGTATCAGGATTTAGTGACCTAATTGAAGATGTCAAGATGGCTTTCGACAGAGATGGTGAGAAGGCAGATATTTCTGT
GAACATGTATGAAGATATCAACATTATCACTGGTGCACTTAAACTGTACTTCAGGGATTTGCCAATTCCACTCATTACATATGATGCCTA
CCCTAAGTTTATAGAATCTGCCAAAATTATGGATCCGGATGAGCAATTGGAAACCCTTCATGAAGCACTGAAACTACTGCCACCTGCTCA
CTGCGAAACCCTCCGGTACCTCATGGCACATCTAAAGAGAGTGACCCTCCACGAAAAGGAGAATCTTATGAATGCAGAGAACCTTGGAAT
CGTCTTTGGACCCACCCTTATGAGATCTCCAGAACTAGACGCCATGGCTGCATTGAATGATATACGGTATCAGAGACTGGTGGTGGAGCT
GCTTATCAAAAACGAAGACATTTTATTTTAAATTTTTAATTTGAGGGGAAAAGAAATGTTTTACAGATGAAGGAATGTTTTATAGTAATT
TAATTTGCTCCTGTAGCTGCATTATTTCTTGATTAGAGGTTTGGGCATATAACCAGATTAAAGTGAAGGAACTTTCTGTTGTTTTTGTAG
CACCGCTCAGCTGTCTTGTAAAACAGTGAACACACGCTTTCTGGTTCTAGTAATCCTGGGTGTTTATCACGTTCAGAGAAACTCAAGCTA
TTGCATGATTAGCCCCCTATCTGGCAAGGAAACCCCATACAGAAGAAACAACAAACCTGCGCCTGCACCGCCTCTGCGTCCTGGGTAGTC
TGTGCTTGTAATCCAGCATGTTTCACAGAGTAAGCCTGTTGTGACTTTGCTTTTGGGGTCTATGTCATTGGTTTCTGATGCTTGTACAAA
CACGCACACACAAATGGATAAAACAGCACCTCTGGCTGTTACATTACCATAAACCATATCACATGCCTACATTTTACAAATGATTTCTGG
TTTCTCTTAGTTCTTCTCTAACATAGTACTTTCTTTCCAGCAAAAGCAAAATGTGTTTTCAGATTTGTTACTTTAATAAAGGTTATCCAT
ACCAATAAAAAGTGTACAACACAGCATTTTCTGTTAAATTATTATTGGTTTTCAGTTGTAATTTGGTATTTTTTCTGGCATGCGTTTATT

>7408_7408_4_ATF2-CHN1_ATF2_chr2_175945388_ENST00000409499_CHN1_chr2_175816930_ENST00000409900_length(amino acids)=522AA_BP=0
MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQSEVTLLRNEVAQLKQLLLAHKDCPVTAMQKKSGYHNTDEYRPPVWKSYLYQLQQEA
PHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLV
TDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHN
FKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGL
NSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLP

--------------------------------------------------------------
>7408_7408_5_ATF2-CHN1_ATF2_chr2_175945388_ENST00000409635_CHN1_chr2_175816930_ENST00000409900_length(transcript)=3667nt_BP=1553nt
GTCAGTCCGATCTCGCGAGAGAGGACGGAAGCCTGTGGGAGCCCGTGGCCTTTAAAGTGCCGTTCAGCCTTTTCCTCCAGGGGTGCTTTG
TAAACACGGCTGTGCTCAGGGCTCGCGGGTGACCGAAAGGATCATGAACTAGTGACCTGGAAAGGGTACTAGATGGAAACTTGAGAAAGG
ACTGCTTATTGATAACAGCTAAGGTATTCCTGGAAGCAGAGTAAATAAAGCTCATGGCCCACCAGCTAGAAAGTATTCTTGCCATGAGAA
AAAGAATGTGATAAGTTATTCAACTTATGAAATTCAAGTTACATGTGAATTCTGCCAGATACTGAATTCATTACTTAAAACCACCCAGAA
GAGAAACCTCCAGGCTCAGATAGCTTCACTGGCAATACAAGGACCTGTGGAATATGAGTGATGACAAACCCTTTCTATGTACTGCGCCTG
GATGTGGCCAGATCAGACCCCAACACCAACAAGATTCTTGAAAAACTGTGAAGAAGTGGGTTTGTTTAATGAGTTGGCGAGTCCATTTGA
GAATGAATTCAAGAAAGCTTCAGAAGATGACATTAAAAAAATGCCTCTAGATTTATCCCCTCTTGCAACACCTATCATAAGAAGCAAAAT
TGAGGAGCCTTCTGTTGTAGAAACAACTCACCAGGATAGTCCTTTACCTCACCCAGAGTCTACTACCAGTGATGAGAAGGAAGTACCATT
GGCACAAACTGCACAGCCCACATCAGCTATTGTTCGTCCAGCATCATTACAGGTTCCCAATGTGCTGCTTACAAGTTCTGACTCAAGTGT
AATTATTCAGCAGGCAGTACCTTCACCAACCTCAAGTACTGTAATCACCCAGGCACCATCCTCTAACAGGCCAATTGTCCCTGTACCAGG
CCCATTTCCTCTTCTGTTACATCTTCCTAATGGACAAACCATGCCTGTTGCTATTCCTGCATCAATTACAAGTTCTAATGTGCATGTTCC
AGCTGCAGTCCCACTCGTTCGACCAGTCACCATGGTGCCTAGTGTTCCAGGAATCCCAGGTCCTTCCTCTCCCCAACCAGTACAGTCAGA
AGCAAAAATGAGATTAAAAGCTGCTTTGACCCAGCAACATCCTCCAGTTACCAATGGTGATACTGTCAAAGGTCATGGTAGCGGATTGGT
TAGGACTCAGTCAGAGGAATCTCGACCGCAGTCATTACAACAGCCAGCCACATCCACTACAGAAACTCCGGCTTCTCCAGCTCACACAAC
TCCACAGACCCAAAGTACAAGTGGTCGTCGGAGAAGAGCAGCTAACGAAGATCCTGATGAAAAAAGGAGAAAGTTTTTAGAGCGAAATAG
AGCAGCAGCTTCAAGATGCCGACAAAAAAGGAAAGTCTGGGTTCAGTCTTTAGAGAAGAAAGCTGAAGACTTGAGTTCATTAAATGGTCA
GCTGCAGAGTGAAGTCACCCTGCTGAGAAATGAAGTGGCACAGCTGAAACAGCTTCTTCTGGCTCATAAAGATTGCCCTGTAACCGCCAT
GCAGAAGAAATCTGGCTATCATAATACAGATGAATATAGACCTCCTGTTTGGAAATCTTACTTATATCAGCTACAACAGGAAGCCCCTCA
TCCTCGAAGAATTACCTGTACTTGCGAGGTGGAAAACAGACCAAAGTATTATGGAAGAGAGTTTCATGGCATGATCTCCAGAGAAGCAGC
CGACCAGCTCTTGATTGTGGCTGAGGGGAGCTACCTCATCCGGGAGAGCCAGCGGCAGCCAGGGACCTACACTTTGGCTTTAAGATTTGG
AAGTCAAACCAGAAACTTCAGGCTCTACTACGATGGCAAGCACTTTGTTGGGGAGAAACGCTTTGAGTCCATCCACGATCTGGTGACTGA
TGGCTTGATTACTCTCTATATTGAAACCAAGGCAGCAGAATACATTGCCAAGATGACGATAAACCCAATTTATGAGCACGTAGGATACAC
AACCTTAAACAGAGAGCCAGCATACAAAAAACATATGCCAGTCCTGAAAGAGACACATGATGAGAGAGATTCTACAGGCCAGGATGGGGT
GTCAGAGAAAAGGTTGACATCACTTGTTAGAAGAGCAACTCTGAAAGAAAACGAGCAAATTCCAAAATATGAAAAGATTCACAATTTCAA
GGTGCATACATTCAGAGGGCCACACTGGTGTGAATACTGTGCCAACTTTATGTGGGGTCTCATTGCTCAGGGAGTGAAATGTGCAGATTG
TGGTTTGAATGTTCATAAGCAGTGTTCCAAGATGGTCCCAAATGACTGTAAGCCAGACTTGAAGCATGTCAAAAAGGTGTACAGCTGTGA
CCTTACGACGCTCGTGAAAGCACATACCACTAAGCGGCCAATGGTGGTAGACATGTGCATCAGGGAGATTGAGTCTAGAGGTCTTAATTC
TGAAGGACTATACCGAGTATCAGGATTTAGTGACCTAATTGAAGATGTCAAGATGGCTTTCGACAGAGATGGTGAGAAGGCAGATATTTC
TGTGAACATGTATGAAGATATCAACATTATCACTGGTGCACTTAAACTGTACTTCAGGGATTTGCCAATTCCACTCATTACATATGATGC
CTACCCTAAGTTTATAGAATCTGCCAAAATTATGGATCCGGATGAGCAATTGGAAACCCTTCATGAAGCACTGAAACTACTGCCACCTGC
TCACTGCGAAACCCTCCGGTACCTCATGGCACATCTAAAGAGAGTGACCCTCCACGAAAAGGAGAATCTTATGAATGCAGAGAACCTTGG
AATCGTCTTTGGACCCACCCTTATGAGATCTCCAGAACTAGACGCCATGGCTGCATTGAATGATATACGGTATCAGAGACTGGTGGTGGA
GCTGCTTATCAAAAACGAAGACATTTTATTTTAAATTTTTAATTTGAGGGGAAAAGAAATGTTTTACAGATGAAGGAATGTTTTATAGTA
ATTTAATTTGCTCCTGTAGCTGCATTATTTCTTGATTAGAGGTTTGGGCATATAACCAGATTAAAGTGAAGGAACTTTCTGTTGTTTTTG
TAGCACCGCTCAGCTGTCTTGTAAAACAGTGAACACACGCTTTCTGGTTCTAGTAATCCTGGGTGTTTATCACGTTCAGAGAAACTCAAG
CTATTGCATGATTAGCCCCCTATCTGGCAAGGAAACCCCATACAGAAGAAACAACAAACCTGCGCCTGCACCGCCTCTGCGTCCTGGGTA
GTCTGTGCTTGTAATCCAGCATGTTTCACAGAGTAAGCCTGTTGTGACTTTGCTTTTGGGGTCTATGTCATTGGTTTCTGATGCTTGTAC
AAACACGCACACACAAATGGATAAAACAGCACCTCTGGCTGTTACATTACCATAAACCATATCACATGCCTACATTTTACAAATGATTTC
TGGTTTCTCTTAGTTCTTCTCTAACATAGTACTTTCTTTCCAGCAAAAGCAAAATGTGTTTTCAGATTTGTTACTTTAATAAAGGTTATC
CATACCAATAAAAAGTGTACAACACAGCATTTTCTGTTAAATTATTATTGGTTTTCAGTTGTAATTTGGTATTTTTTCTGGCATGCGTTT

>7408_7408_5_ATF2-CHN1_ATF2_chr2_175945388_ENST00000409635_CHN1_chr2_175816930_ENST00000409900_length(amino acids)=825AA_BP=0
MYCAWMWPDQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDE
KEVPLAQTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSS
NVHVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKMRLKAALTQQHPPVTNGDTVKGHGSGLVRTQSEESRPQSLQQPATSTTETPAS
PAHTTPQTQSTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDC
PVTAMQKKSGYHNTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTL
ALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDST
GQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKK
VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPL
ITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ATF2-CHN1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATF2-CHN1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATF2-CHN1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource