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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RNF111-SLTM (FusionGDB2 ID:74699)

Fusion Gene Summary for RNF111-SLTM

check button Fusion gene summary
Fusion gene informationFusion gene name: RNF111-SLTM
Fusion gene ID: 74699
HgeneTgene
Gene symbol

RNF111

SLTM

Gene ID

54778

79811

Gene namering finger protein 111SAFB like transcription modulator
SynonymsARK|hRNF111Met
Cytomap

15q22.1-q22.2

15q22.1

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase ArkadiaArkadiaRING-type E3 ubiquitin transferase ArkadiaSAFB-like transcription modulatormodulator of estrogen-induced transcription
Modification date2020032720200313
UniProtAcc.

Q9NWH9

Ensembl transtripts involved in fusion geneENST00000348370, ENST00000434298, 
ENST00000557998, ENST00000559209, 
ENST00000561186, ENST00000560080, 
ENST00000536328, ENST00000557950, 
ENST00000380516, 
Fusion gene scores* DoF score11 X 8 X 9=79212 X 15 X 5=900
# samples 1416
** MAII scorelog2(14/792*10)=-2.50007360313464
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/900*10)=-2.49185309632967
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RNF111 [Title/Abstract] AND SLTM [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRNF111(59359282)-SLTM(59193486), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across RNF111 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLTM (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-ZF-A9RN-01ARNF111chr15

59359282

-SLTMchr15

59193486

-
ChimerDB4BLCATCGA-ZF-A9RNRNF111chr15

59359282

+SLTMchr15

59193486

-
ChimerDB4CESCTCGA-C5-A3HE-01ARNF111chr15

59323901

-SLTMchr15

59209198

-


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Fusion Gene ORF analysis for RNF111-SLTM

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000348370ENST00000536328RNF111chr15

59359282

+SLTMchr15

59193486

-
5CDS-5UTRENST00000348370ENST00000536328RNF111chr15

59323901

-SLTMchr15

59209198

-
5CDS-5UTRENST00000348370ENST00000557950RNF111chr15

59359282

+SLTMchr15

59193486

-
5CDS-5UTRENST00000348370ENST00000557950RNF111chr15

59323901

-SLTMchr15

59209198

-
5CDS-5UTRENST00000434298ENST00000536328RNF111chr15

59359282

+SLTMchr15

59193486

-
5CDS-5UTRENST00000434298ENST00000536328RNF111chr15

59323901

-SLTMchr15

59209198

-
5CDS-5UTRENST00000434298ENST00000557950RNF111chr15

59359282

+SLTMchr15

59193486

-
5CDS-5UTRENST00000434298ENST00000557950RNF111chr15

59323901

-SLTMchr15

59209198

-
5CDS-5UTRENST00000557998ENST00000536328RNF111chr15

59359282

+SLTMchr15

59193486

-
5CDS-5UTRENST00000557998ENST00000536328RNF111chr15

59323901

-SLTMchr15

59209198

-
5CDS-5UTRENST00000557998ENST00000557950RNF111chr15

59359282

+SLTMchr15

59193486

-
5CDS-5UTRENST00000557998ENST00000557950RNF111chr15

59323901

-SLTMchr15

59209198

-
5CDS-5UTRENST00000559209ENST00000536328RNF111chr15

59359282

+SLTMchr15

59193486

-
5CDS-5UTRENST00000559209ENST00000536328RNF111chr15

59323901

-SLTMchr15

59209198

-
5CDS-5UTRENST00000559209ENST00000557950RNF111chr15

59359282

+SLTMchr15

59193486

-
5CDS-5UTRENST00000559209ENST00000557950RNF111chr15

59323901

-SLTMchr15

59209198

-
5CDS-5UTRENST00000561186ENST00000536328RNF111chr15

59359282

+SLTMchr15

59193486

-
5CDS-5UTRENST00000561186ENST00000536328RNF111chr15

59323901

-SLTMchr15

59209198

-
5CDS-5UTRENST00000561186ENST00000557950RNF111chr15

59359282

+SLTMchr15

59193486

-
5CDS-5UTRENST00000561186ENST00000557950RNF111chr15

59323901

-SLTMchr15

59209198

-
In-frameENST00000348370ENST00000380516RNF111chr15

59359282

+SLTMchr15

59193486

-
In-frameENST00000348370ENST00000380516RNF111chr15

59323901

-SLTMchr15

59209198

-
In-frameENST00000434298ENST00000380516RNF111chr15

59359282

+SLTMchr15

59193486

-
In-frameENST00000434298ENST00000380516RNF111chr15

59323901

-SLTMchr15

59209198

-
In-frameENST00000557998ENST00000380516RNF111chr15

59359282

+SLTMchr15

59193486

-
In-frameENST00000557998ENST00000380516RNF111chr15

59323901

-SLTMchr15

59209198

-
In-frameENST00000559209ENST00000380516RNF111chr15

59359282

+SLTMchr15

59193486

-
In-frameENST00000559209ENST00000380516RNF111chr15

59323901

-SLTMchr15

59209198

-
In-frameENST00000561186ENST00000380516RNF111chr15

59359282

+SLTMchr15

59193486

-
In-frameENST00000561186ENST00000380516RNF111chr15

59323901

-SLTMchr15

59209198

-
intron-3CDSENST00000560080ENST00000380516RNF111chr15

59359282

+SLTMchr15

59193486

-
intron-3CDSENST00000560080ENST00000380516RNF111chr15

59323901

-SLTMchr15

59209198

-
intron-5UTRENST00000560080ENST00000536328RNF111chr15

59359282

+SLTMchr15

59193486

-
intron-5UTRENST00000560080ENST00000536328RNF111chr15

59323901

-SLTMchr15

59209198

-
intron-5UTRENST00000560080ENST00000557950RNF111chr15

59359282

+SLTMchr15

59193486

-
intron-5UTRENST00000560080ENST00000557950RNF111chr15

59323901

-SLTMchr15

59209198

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000348370RNF111chr1559359282+ENST00000380516SLTMchr1559193486-5617211943346621409
ENST00000434298RNF111chr1559359282+ENST00000380516SLTMchr1559193486-5606210842246511409
ENST00000559209RNF111chr1559359282+ENST00000380516SLTMchr1559193486-5320182213643651409
ENST00000557998RNF111chr1559359282+ENST00000380516SLTMchr1559193486-5471197328745161409
ENST00000561186RNF111chr1559359282+ENST00000380516SLTMchr1559193486-51841686042291409
ENST00000348370RNF111chr1559323901-ENST00000380516SLTMchr1559209198-5122131343341671244
ENST00000434298RNF111chr1559323901-ENST00000380516SLTMchr1559209198-5111130242241561244
ENST00000559209RNF111chr1559323901-ENST00000380516SLTMchr1559209198-4825101613638701244
ENST00000557998RNF111chr1559323901-ENST00000380516SLTMchr1559209198-4976116728740211244
ENST00000561186RNF111chr1559323901-ENST00000380516SLTMchr1559209198-4689880037341244

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000348370ENST00000380516RNF111chr1559359282+SLTMchr1559193486-0.0007688390.9992312
ENST00000434298ENST00000380516RNF111chr1559359282+SLTMchr1559193486-0.0007655240.99923444
ENST00000559209ENST00000380516RNF111chr1559359282+SLTMchr1559193486-0.0005269540.99947304
ENST00000557998ENST00000380516RNF111chr1559359282+SLTMchr1559193486-0.0006071670.99939287
ENST00000561186ENST00000380516RNF111chr1559359282+SLTMchr1559193486-0.0005303750.9994697
ENST00000348370ENST00000380516RNF111chr1559323901-SLTMchr1559209198-0.0003882870.9996118
ENST00000434298ENST00000380516RNF111chr1559323901-SLTMchr1559209198-0.0003859560.99961406
ENST00000559209ENST00000380516RNF111chr1559323901-SLTMchr1559209198-0.0002611020.9997389
ENST00000557998ENST00000380516RNF111chr1559323901-SLTMchr1559209198-0.0003015720.9996984
ENST00000561186ENST00000380516RNF111chr1559323901-SLTMchr1559209198-0.000265510.99973446

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Fusion Genomic Features for RNF111-SLTM


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RNF111-SLTM


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:59359282/chr15:59193486)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.SLTM

Q9NWH9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF111chr15:59359282chr15:59193486ENST00000348370+614252_464562987.0Compositional biasNote=Ser-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000348370+614494_523562987.0Compositional biasNote=His-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000434298+614252_4645621004.0Compositional biasNote=Ser-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000434298+614494_5235621004.0Compositional biasNote=His-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000557998+614252_464562995.0Compositional biasNote=Ser-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000557998+614494_523562995.0Compositional biasNote=His-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000559209+614252_464562996.0Compositional biasNote=Ser-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000559209+614494_523562996.0Compositional biasNote=His-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000561186+513252_4645621004.0Compositional biasNote=Ser-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000561186+513494_5235621004.0Compositional biasNote=His-rich
TgeneSLTMchr15:59323901chr15:59209198ENST00000380516121609_728831035.0Coiled coilOntology_term=ECO:0000255
TgeneSLTMchr15:59359282chr15:59193486ENST00000380516421609_7281871035.0Coiled coilOntology_term=ECO:0000255
TgeneSLTMchr15:59323901chr15:59209198ENST00000380516121108_239831035.0Compositional biasNote=Glu-rich
TgeneSLTMchr15:59323901chr15:59209198ENST00000380516121569_906831035.0Compositional biasNote=Arg/Glu-rich
TgeneSLTMchr15:59359282chr15:59193486ENST00000380516421569_9061871035.0Compositional biasNote=Arg/Glu-rich
TgeneSLTMchr15:59323901chr15:59209198ENST00000380516121384_462831035.0DomainRRM
TgeneSLTMchr15:59359282chr15:59193486ENST00000380516421384_4621871035.0DomainRRM

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF111chr15:59323901chr15:59209198ENST00000348370-214252_464293987.0Compositional biasNote=Ser-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000348370-214494_523293987.0Compositional biasNote=His-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000348370-214629_781293987.0Compositional biasNote=Pro-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000434298-214252_4642931004.0Compositional biasNote=Ser-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000434298-214494_5232931004.0Compositional biasNote=His-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000434298-214629_7812931004.0Compositional biasNote=Pro-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000557998-214252_464293995.0Compositional biasNote=Ser-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000557998-214494_523293995.0Compositional biasNote=His-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000557998-214629_781293995.0Compositional biasNote=Pro-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000559209-214252_464293996.0Compositional biasNote=Ser-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000559209-214494_523293996.0Compositional biasNote=His-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000559209-214629_781293996.0Compositional biasNote=Pro-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000561186-113252_4642931004.0Compositional biasNote=Ser-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000561186-113494_5232931004.0Compositional biasNote=His-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000561186-113629_7812931004.0Compositional biasNote=Pro-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000348370+614629_781562987.0Compositional biasNote=Pro-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000434298+614629_7815621004.0Compositional biasNote=Pro-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000557998+614629_781562995.0Compositional biasNote=Pro-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000559209+614629_781562996.0Compositional biasNote=Pro-rich
HgeneRNF111chr15:59359282chr15:59193486ENST00000561186+513629_7815621004.0Compositional biasNote=Pro-rich
HgeneRNF111chr15:59323901chr15:59209198ENST00000348370-214907_909293987.0RegionUbiquitin binding
HgeneRNF111chr15:59323901chr15:59209198ENST00000348370-214957_961293987.0RegionUbiquitin binding
HgeneRNF111chr15:59323901chr15:59209198ENST00000434298-214907_9092931004.0RegionUbiquitin binding
HgeneRNF111chr15:59323901chr15:59209198ENST00000434298-214957_9612931004.0RegionUbiquitin binding
HgeneRNF111chr15:59323901chr15:59209198ENST00000557998-214907_909293995.0RegionUbiquitin binding
HgeneRNF111chr15:59323901chr15:59209198ENST00000557998-214957_961293995.0RegionUbiquitin binding
HgeneRNF111chr15:59323901chr15:59209198ENST00000559209-214907_909293996.0RegionUbiquitin binding
HgeneRNF111chr15:59323901chr15:59209198ENST00000559209-214957_961293996.0RegionUbiquitin binding
HgeneRNF111chr15:59323901chr15:59209198ENST00000561186-113907_9092931004.0RegionUbiquitin binding
HgeneRNF111chr15:59323901chr15:59209198ENST00000561186-113957_9612931004.0RegionUbiquitin binding
HgeneRNF111chr15:59359282chr15:59193486ENST00000348370+614907_909562987.0RegionUbiquitin binding
HgeneRNF111chr15:59359282chr15:59193486ENST00000348370+614957_961562987.0RegionUbiquitin binding
HgeneRNF111chr15:59359282chr15:59193486ENST00000434298+614907_9095621004.0RegionUbiquitin binding
HgeneRNF111chr15:59359282chr15:59193486ENST00000434298+614957_9615621004.0RegionUbiquitin binding
HgeneRNF111chr15:59359282chr15:59193486ENST00000557998+614907_909562995.0RegionUbiquitin binding
HgeneRNF111chr15:59359282chr15:59193486ENST00000557998+614957_961562995.0RegionUbiquitin binding
HgeneRNF111chr15:59359282chr15:59193486ENST00000559209+614907_909562996.0RegionUbiquitin binding
HgeneRNF111chr15:59359282chr15:59193486ENST00000559209+614957_961562996.0RegionUbiquitin binding
HgeneRNF111chr15:59359282chr15:59193486ENST00000561186+513907_9095621004.0RegionUbiquitin binding
HgeneRNF111chr15:59359282chr15:59193486ENST00000561186+513957_9615621004.0RegionUbiquitin binding
HgeneRNF111chr15:59323901chr15:59209198ENST00000348370-214942_983293987.0Zinc fingerRING-type%3B atypical
HgeneRNF111chr15:59323901chr15:59209198ENST00000434298-214942_9832931004.0Zinc fingerRING-type%3B atypical
HgeneRNF111chr15:59323901chr15:59209198ENST00000557998-214942_983293995.0Zinc fingerRING-type%3B atypical
HgeneRNF111chr15:59323901chr15:59209198ENST00000559209-214942_983293996.0Zinc fingerRING-type%3B atypical
HgeneRNF111chr15:59323901chr15:59209198ENST00000561186-113942_9832931004.0Zinc fingerRING-type%3B atypical
HgeneRNF111chr15:59359282chr15:59193486ENST00000348370+614942_983562987.0Zinc fingerRING-type%3B atypical
HgeneRNF111chr15:59359282chr15:59193486ENST00000434298+614942_9835621004.0Zinc fingerRING-type%3B atypical
HgeneRNF111chr15:59359282chr15:59193486ENST00000557998+614942_983562995.0Zinc fingerRING-type%3B atypical
HgeneRNF111chr15:59359282chr15:59193486ENST00000559209+614942_983562996.0Zinc fingerRING-type%3B atypical
HgeneRNF111chr15:59359282chr15:59193486ENST00000561186+513942_9835621004.0Zinc fingerRING-type%3B atypical
TgeneSLTMchr15:59359282chr15:59193486ENST00000380516421108_2391871035.0Compositional biasNote=Glu-rich
TgeneSLTMchr15:59323901chr15:59209198ENST0000038051612122_56831035.0DomainSAP
TgeneSLTMchr15:59359282chr15:59193486ENST0000038051642122_561871035.0DomainSAP


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Fusion Gene Sequence for RNF111-SLTM


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>74699_74699_1_RNF111-SLTM_RNF111_chr15_59323901_ENST00000348370_SLTM_chr15_59209198_ENST00000380516_length(transcript)=5122nt_BP=1313nt
AGAGCCCTAGTGTCGTGCTCTCCTCGGTAGGGGAGGAATTGGTTAGGCGGCGGCGGCGGCGAAGCGGCGGCGGCGGCTGTAGGGGAGCAG
CGGCAGTGGCGGCGACGGCGAGGAGGTGTTCGGTTTGCGCAGCGTAGAAACGCCCGCAGCTTCAGAGAAGGAGTTCTTGTGGGACCAAAT
TAGGCATTCTGAACCCACGCCGGCTTAGCTGGGCCGAGTCCAGGCGCTGCCGCACGTACAGTTTTGGTGGCGGTGACAGACACTGTTCTT
GACTCTAGGGGCCTATTAGGCCGACGTCTGAGGCGCAGATCGCTGGCTCTCGACGCATTACTCTTTACGCCTTACATTTCTGTCTTCCTT
CCTGGGTCAGTGATTCCCGGACCCTGGAAGAGAAGAGGGTGGCTAATGATTAAGGCTTTCCTTAAAGTTTCCCATGTCTCAATGGACTCC
TGAATATAACGAGCTCTACACCTTAAAAGTGGATATGAAGAGTGAGATTCCTTCTGATGCACCAAAGACACAGGAGAGTCTGAAAGGGAT
CCTTTTGCATCCAGAGCCCATTGGGGCAGCCAAAAGTTTTCCTGCAGGAGTTGAGATGATTAATAGTAAAGTGGGGAATGAATTCTCTCA
CCTGTGTGATGATTCTCAAAAGCAAGAGAAGGAAATGAATGGTAACCAGCAAGAACAAGAAAAAAGTCTCGTTGTGAGGAAAAAACGCAA
AAGCCAGCAGGCTGGCCCTTCGTATGTGCAGAATTGTGTTAAAGAAAACCAGGGAATATTAGGACTGAGGCAACACCTAGGGACACCAAG
TGATGAAGATAATGATTCCTCTTTTAGTGATTGTCTTTCTTCTCCTTCATCTAGTCTGCATTTTGGAGATTCTGATACTGTGACTTCAGA
TGAGGATAAAGAAGTCTCTGTAAGACATTCCCAGACCATTTTGAATGCTAAAAGTAGAAGCCATAGTGCACGGTCTCATAAGTGGCCTCG
GACTGAGACAGAATCTGTATCGGGATTGTTAATGAAAAGACCCTGTTTACATGGCAGTTCGTTACGGAGACTTCCATGCAGAAAGAGATT
TGTAAAAAATAATTCCTCACAGAGGACACAGAAACAAAAAGAGAGGATATTAATGCAGAGGAAGAAACGAGAAGTGTTAGCTCGAAGAAA
ATATGCCTTGCTACCTAGTTCTAGTAGTTCCAGTGAGAATGACCTCAGCAGTGAATCCTCTTCTAGCTCATCAACTGAAGGAGAAGAAGA
TTTGTTTGTTTCTGCCAGTGAAAACCACCAAAACAATCCAGCTGTTCCCTCAGGTAAAAAACATGAAGCAGATGAGTTGAGTGGAGATGC
TTCTGTGGAAGATGATGCTTTTATCAAGGACTGTGAATTGGAGAATCAAGAGGCACATGAGCAAGATGGAAATGATGAACTAAAGGACTC
TGAAGAATTTGGTGAAAATGAAGAAGAAAATGTGCATTCCAAGGAGTTACTCTCTGCAGAAGAAAACAAGAGAGCTCATGAATTAATAGA
GGCAGAAGGAATAGAAGATATAGAAAAAGAGGACATCGAAAGTCAGGAAATTGAAGCTCAAGAAGGTGAAGATGATACCTTTCTAACAGC
CCAAGATGGTGAGGAAGAAGAAAATGAGAAAGATATAGCAGGTTCTGGTGATGGTACACAAGAAGTATCTAAACCTCTTCCTTCAGAAGG
GAGCCTAGCTGAGGCTGATCACACAGCTCATGAAGAGATGGAAGCTCATACGACTGTGAAAGAAGCTGAGGATGACAACATCTCGGTCAC
AATCCAGGCTGAAGATGCCATCACTCTGGATTTTGATGGTGATGACCTCCTAGAAACAGGTAAAAATGTGAAAATTACAGATTCTGAAGC
AAGTAAGCCAAAAGATGGGCAGGACGCCATTGCACAGAGCCCGGAGAAGGAAAGCAAGGATTATGAGATGAATGCGAACCATAAAGATGG
TAAGAAGGAAGACTGCGTGAAGGGTGACCCTGTCGAGAAGGAAGCCAGAGAAAGTTCTAAGAAAGCAGAATCTGGAGACAAAGAAAAGGA
TACTTTGAAGAAAGGGCCCTCGTCTACTGGGGCCTCTGGTCAAGCAAAGAGCTCTTCAAAGGAATCTAAAGACAGCAAGACATCATCTAA
AGATGACAAAGGAAGTACAAGTAGTACTAGTGGTAGCAGTGGAAGCTCAACTAAAAATATCTGGGTTAGTGGACTTTCATCTAATACCAA
AGCTGCTGATTTGAAGAACCTCTTTGGCAAATATGGAAAGGTTCTGAGTGCAAAAGTAGTTACAAATGCTCGAAGTCCTGGGGCAAAATG
CTATGGCATTGTAACTATGTCTTCAAGCACAGAGGTGTCCAGGTGTATTGCACATCTTCATCGCACTGAGCTGCATGGACAGCTGATTTC
TGTTGAAAAAGTAAAAGGTGATCCCTCTAAGAAAGAAATGAAGAAAGAAAATGATGAAAAGAGTAGTTCAAGAAGTTCTGGAGATAAAAA
AAATACGAGTGATAGAAGTAGCAAGACACAAGCCTCTGTCAAAAAAGAAGAGAAAAGATCGTCTGAGAAATCTGAAAAAAAAGAAAGCAA
GGATACTAAGAAAATAGAAGGTAAAGATGAGAAGAATGATAATGGAGCAAGTGGCCAAACATCAGAATCGATTAAAAAAAGTGAAGAAAA
GAAGCGAATAAGTTCCAAGAGTCCAGGACATATGGTAATACTAGACCAAACTAAAGGAGATCATTGTAGACCATCAAGAAGAGGAAGATA
TGAGAAAATTCATGGAAGAAGTAAGGAAAAGGAGAGAGCTAGTCTAGATAAAAAAAGAGATAAAGACTACAGAAGGAAAGAGATCTTGCC
TTTTGAAAAGATGAAGGAACAAAGGTTGAGAGAACATTTAGTTCGTTTTGAAAGGCTGCGACGAGCAATGGAACTTCGAAGACGAAGAGA
GATTGCAGAGAGAGAGCGTCGAGAGCGAGAACGCATTAGAATAATTCGTGAACGGGAAGAACGGGAACGCTTACAGAGAGAGAGAGAGCG
CCTAGAAATTGAAAGGCAAAAACTAGAGAGAGAGAGAATGGAACGCGAACGCTTGGAAAGGGAACGCATTCGTATTGAACAGGAACGTCG
TAAGGAAGCTGAACGGATTGCTCGAGAAAGAGAGGAACTCAGAAGGCAACAACAGCAGCTTCGTTATGAACAAGAAAAAAGGAATTCCTT
GAAACGCCCACGTGATGTAGATCATAGGCGAGATGATCCTTACTGGAGCGAGAATAAAAAGTTGTCTCTAGATACAGATGCACGATTTGG
CCATGGATCCGACTACTCTCGCCAACAGAACAGATTTAATGACTTTGATCACCGAGAGAGGGGCAGGTTTCCTGAGAGTTCAGCAGTACA
GTCTTCATCTTTTGAAAGGCGGGATCGCTTTGTTGGTCAAAGTGAGGGGAAAAAAGCACGACCTACTGCACGAAGGGAAGATCCAAGCTT
CGAAAGATATCCCAAAAATTTCAGTGACTCCAGAAGAAATGAGCCTCCACCACCAAGAAATGAACTTAGAGAATCAGACAGGCGAGAAGT
ACGAGGGGAGCGAGACGAAAGGAGAACGGTGATTATTCATGACAGGCCTGATATCACTCATCCTAGACATCCTCGAGAGGCAGGGCCCAA
TCCTTCCAGACCCACCAGCTGGAAAAGTGAAGGAAGCATGTCCACTGACAAACGGGAAACAAGAGTTGAAAGGCCAGAACGATCTGGGAG
AGAAGTATCAGGGCACAGTGTGAGAGGCGCTCCCCCTGGGAATCGTAGCAGCGCTTCGGGGTACGGGAGCAGAGAGGGAGACAGAGGAGT
CATCACAGACCGAGGAGGTGGATCACAGCACTATCCTGAGGAGCGACATGTGGTTGAACGCCATGGACGGGACACAAGCGGACCAAGGAA
AGAGTGGCATGGTCCACCCTCTCAAGGGCCTAGCTATCATGATACGAGGCGAATGGGTGACGGCCGGGCAGGAGCAGGCATGATAACCCA
ACATTCAAGTAACGCATCCCCAATTAATAGAATTGTACAAATCAGTGGCAATTCCATGCCAAGAGGAAGTGGCTCCGGATTTAAGCCATT
TAAGGGTGGACCTCCGCGACGATTCTGAAAATGAGCTCTCTGCCAAGGTTTTAAGATAATTTATTGAAATCTCCTGTAAACTTTACTTGA
CTACTTATGAAGAGGACCTCTGACTTGCTTGAGAGTTCTGTCAGACTTTTCTTTTTAAAAATTTAACATGATTGCTTTTCTCAATTTTGG
AGAAGATGTTTAAATAGTTCTGTTGTAACTTTTAATAGTTTTGTGTATCATTCAACTTTTTTTCTTGCAGCACCGAGGCACATTTGAAAA
GATGGAATTGAAGTCGTTTTGTTTAACGCTGTGTGAATATAAAGAGTAGTTTGCAGCTGTGTGGTAGTGGTTTAATTTGCAGCCTTAGCT
CTGTGGTGTCTGGCTCTAGAGTTACTTCTTTTTACCAAGCATTTTCAGCCTCCATTTTGAAGGCTGTCTACACTTAAGAAGTCTTAGCTG
TCTAATTTTTAGAGAATAAGATTGTTCATTGCATTTCTGAGTATTATGTAACCTATTTTTGCAGAAGGTACTGTTACATTAAGTGCATCT
GTGTATCCTGGTTTAAAAAAATGTAATCTTTTTTGAAATAAACCTTCATATTCTGTATAGTTGCTAAAGTGTTGAGAACCTTTTTAATTG
TAAAATGAGAACCGATTTTCAGTTTAGTGTAGCAGCACACTTGTTCAGGTTTGCATGGTATGAAACCAAATAGATTCATGAAACCTTGGC
CATGAGGTTTGTTTCACAAGGTTCTTAGACCGAGTTGTGCAGGTAAGTGCACTTTTAGGTAATCTGCACTGTTTGTTTGATGGATAAATT
CCATCTCTGGGAATTGTGTGGGTATTAATGTTTCCATGTTCCCAACTATGTTGAGAAGTGGAAAAAAACCCAGGTTCTAGATGGGTGAAT

>74699_74699_1_RNF111-SLTM_RNF111_chr15_59323901_ENST00000348370_SLTM_chr15_59209198_ENST00000380516_length(amino acids)=1244AA_BP=293
MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLV
VRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR
SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSS
TEGEEDLFVSASENHQNNPAVPSGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKR
AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAED
DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAES
GDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR
SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKS
EKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR
RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIR
IEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP
ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHP
REAGPNPSRPTSWKSEGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD

--------------------------------------------------------------
>74699_74699_2_RNF111-SLTM_RNF111_chr15_59323901_ENST00000434298_SLTM_chr15_59209198_ENST00000380516_length(transcript)=5111nt_BP=1302nt
GTCGTGCTCTCCTCGGTAGGGGAGGAATTGGTTAGGCGGCGGCGGCGGCGAAGCGGCGGCGGCGGCTGTAGGGGAGCAGCGGCAGTGGCG
GCGACGGCGAGGAGGTGTTCGGTTTGCGCAGCGTAGAAACGCCCGCAGCTTCAGAGAAGGAGTTCTTGTGGGACCAAATTAGGCATTCTG
AACCCACGCCGGCTTAGCTGGGCCGAGTCCAGGCGCTGCCGCACGTACAGTTTTGGTGGCGGTGACAGACACTGTTCTTGACTCTAGGGG
CCTATTAGGCCGACGTCTGAGGCGCAGATCGCTGGCTCTCGACGCATTACTCTTTACGCCTTACATTTCTGTCTTCCTTCCTGGGTCAGT
GATTCCCGGACCCTGGAAGAGAAGAGGGTGGCTAATGATTAAGGCTTTCCTTAAAGTTTCCCATGTCTCAATGGACTCCTGAATATAACG
AGCTCTACACCTTAAAAGTGGATATGAAGAGTGAGATTCCTTCTGATGCACCAAAGACACAGGAGAGTCTGAAAGGGATCCTTTTGCATC
CAGAGCCCATTGGGGCAGCCAAAAGTTTTCCTGCAGGAGTTGAGATGATTAATAGTAAAGTGGGGAATGAATTCTCTCACCTGTGTGATG
ATTCTCAAAAGCAAGAGAAGGAAATGAATGGTAACCAGCAAGAACAAGAAAAAAGTCTCGTTGTGAGGAAAAAACGCAAAAGCCAGCAGG
CTGGCCCTTCGTATGTGCAGAATTGTGTTAAAGAAAACCAGGGAATATTAGGACTGAGGCAACACCTAGGGACACCAAGTGATGAAGATA
ATGATTCCTCTTTTAGTGATTGTCTTTCTTCTCCTTCATCTAGTCTGCATTTTGGAGATTCTGATACTGTGACTTCAGATGAGGATAAAG
AAGTCTCTGTAAGACATTCCCAGACCATTTTGAATGCTAAAAGTAGAAGCCATAGTGCACGGTCTCATAAGTGGCCTCGGACTGAGACAG
AATCTGTATCGGGATTGTTAATGAAAAGACCCTGTTTACATGGCAGTTCGTTACGGAGACTTCCATGCAGAAAGAGATTTGTAAAAAATA
ATTCCTCACAGAGGACACAGAAACAAAAAGAGAGGATATTAATGCAGAGGAAGAAACGAGAAGTGTTAGCTCGAAGAAAATATGCCTTGC
TACCTAGTTCTAGTAGTTCCAGTGAGAATGACCTCAGCAGTGAATCCTCTTCTAGCTCATCAACTGAAGGAGAAGAAGATTTGTTTGTTT
CTGCCAGTGAAAACCACCAAAACAATCCAGCTGTTCCCTCAGGTAAAAAACATGAAGCAGATGAGTTGAGTGGAGATGCTTCTGTGGAAG
ATGATGCTTTTATCAAGGACTGTGAATTGGAGAATCAAGAGGCACATGAGCAAGATGGAAATGATGAACTAAAGGACTCTGAAGAATTTG
GTGAAAATGAAGAAGAAAATGTGCATTCCAAGGAGTTACTCTCTGCAGAAGAAAACAAGAGAGCTCATGAATTAATAGAGGCAGAAGGAA
TAGAAGATATAGAAAAAGAGGACATCGAAAGTCAGGAAATTGAAGCTCAAGAAGGTGAAGATGATACCTTTCTAACAGCCCAAGATGGTG
AGGAAGAAGAAAATGAGAAAGATATAGCAGGTTCTGGTGATGGTACACAAGAAGTATCTAAACCTCTTCCTTCAGAAGGGAGCCTAGCTG
AGGCTGATCACACAGCTCATGAAGAGATGGAAGCTCATACGACTGTGAAAGAAGCTGAGGATGACAACATCTCGGTCACAATCCAGGCTG
AAGATGCCATCACTCTGGATTTTGATGGTGATGACCTCCTAGAAACAGGTAAAAATGTGAAAATTACAGATTCTGAAGCAAGTAAGCCAA
AAGATGGGCAGGACGCCATTGCACAGAGCCCGGAGAAGGAAAGCAAGGATTATGAGATGAATGCGAACCATAAAGATGGTAAGAAGGAAG
ACTGCGTGAAGGGTGACCCTGTCGAGAAGGAAGCCAGAGAAAGTTCTAAGAAAGCAGAATCTGGAGACAAAGAAAAGGATACTTTGAAGA
AAGGGCCCTCGTCTACTGGGGCCTCTGGTCAAGCAAAGAGCTCTTCAAAGGAATCTAAAGACAGCAAGACATCATCTAAAGATGACAAAG
GAAGTACAAGTAGTACTAGTGGTAGCAGTGGAAGCTCAACTAAAAATATCTGGGTTAGTGGACTTTCATCTAATACCAAAGCTGCTGATT
TGAAGAACCTCTTTGGCAAATATGGAAAGGTTCTGAGTGCAAAAGTAGTTACAAATGCTCGAAGTCCTGGGGCAAAATGCTATGGCATTG
TAACTATGTCTTCAAGCACAGAGGTGTCCAGGTGTATTGCACATCTTCATCGCACTGAGCTGCATGGACAGCTGATTTCTGTTGAAAAAG
TAAAAGGTGATCCCTCTAAGAAAGAAATGAAGAAAGAAAATGATGAAAAGAGTAGTTCAAGAAGTTCTGGAGATAAAAAAAATACGAGTG
ATAGAAGTAGCAAGACACAAGCCTCTGTCAAAAAAGAAGAGAAAAGATCGTCTGAGAAATCTGAAAAAAAAGAAAGCAAGGATACTAAGA
AAATAGAAGGTAAAGATGAGAAGAATGATAATGGAGCAAGTGGCCAAACATCAGAATCGATTAAAAAAAGTGAAGAAAAGAAGCGAATAA
GTTCCAAGAGTCCAGGACATATGGTAATACTAGACCAAACTAAAGGAGATCATTGTAGACCATCAAGAAGAGGAAGATATGAGAAAATTC
ATGGAAGAAGTAAGGAAAAGGAGAGAGCTAGTCTAGATAAAAAAAGAGATAAAGACTACAGAAGGAAAGAGATCTTGCCTTTTGAAAAGA
TGAAGGAACAAAGGTTGAGAGAACATTTAGTTCGTTTTGAAAGGCTGCGACGAGCAATGGAACTTCGAAGACGAAGAGAGATTGCAGAGA
GAGAGCGTCGAGAGCGAGAACGCATTAGAATAATTCGTGAACGGGAAGAACGGGAACGCTTACAGAGAGAGAGAGAGCGCCTAGAAATTG
AAAGGCAAAAACTAGAGAGAGAGAGAATGGAACGCGAACGCTTGGAAAGGGAACGCATTCGTATTGAACAGGAACGTCGTAAGGAAGCTG
AACGGATTGCTCGAGAAAGAGAGGAACTCAGAAGGCAACAACAGCAGCTTCGTTATGAACAAGAAAAAAGGAATTCCTTGAAACGCCCAC
GTGATGTAGATCATAGGCGAGATGATCCTTACTGGAGCGAGAATAAAAAGTTGTCTCTAGATACAGATGCACGATTTGGCCATGGATCCG
ACTACTCTCGCCAACAGAACAGATTTAATGACTTTGATCACCGAGAGAGGGGCAGGTTTCCTGAGAGTTCAGCAGTACAGTCTTCATCTT
TTGAAAGGCGGGATCGCTTTGTTGGTCAAAGTGAGGGGAAAAAAGCACGACCTACTGCACGAAGGGAAGATCCAAGCTTCGAAAGATATC
CCAAAAATTTCAGTGACTCCAGAAGAAATGAGCCTCCACCACCAAGAAATGAACTTAGAGAATCAGACAGGCGAGAAGTACGAGGGGAGC
GAGACGAAAGGAGAACGGTGATTATTCATGACAGGCCTGATATCACTCATCCTAGACATCCTCGAGAGGCAGGGCCCAATCCTTCCAGAC
CCACCAGCTGGAAAAGTGAAGGAAGCATGTCCACTGACAAACGGGAAACAAGAGTTGAAAGGCCAGAACGATCTGGGAGAGAAGTATCAG
GGCACAGTGTGAGAGGCGCTCCCCCTGGGAATCGTAGCAGCGCTTCGGGGTACGGGAGCAGAGAGGGAGACAGAGGAGTCATCACAGACC
GAGGAGGTGGATCACAGCACTATCCTGAGGAGCGACATGTGGTTGAACGCCATGGACGGGACACAAGCGGACCAAGGAAAGAGTGGCATG
GTCCACCCTCTCAAGGGCCTAGCTATCATGATACGAGGCGAATGGGTGACGGCCGGGCAGGAGCAGGCATGATAACCCAACATTCAAGTA
ACGCATCCCCAATTAATAGAATTGTACAAATCAGTGGCAATTCCATGCCAAGAGGAAGTGGCTCCGGATTTAAGCCATTTAAGGGTGGAC
CTCCGCGACGATTCTGAAAATGAGCTCTCTGCCAAGGTTTTAAGATAATTTATTGAAATCTCCTGTAAACTTTACTTGACTACTTATGAA
GAGGACCTCTGACTTGCTTGAGAGTTCTGTCAGACTTTTCTTTTTAAAAATTTAACATGATTGCTTTTCTCAATTTTGGAGAAGATGTTT
AAATAGTTCTGTTGTAACTTTTAATAGTTTTGTGTATCATTCAACTTTTTTTCTTGCAGCACCGAGGCACATTTGAAAAGATGGAATTGA
AGTCGTTTTGTTTAACGCTGTGTGAATATAAAGAGTAGTTTGCAGCTGTGTGGTAGTGGTTTAATTTGCAGCCTTAGCTCTGTGGTGTCT
GGCTCTAGAGTTACTTCTTTTTACCAAGCATTTTCAGCCTCCATTTTGAAGGCTGTCTACACTTAAGAAGTCTTAGCTGTCTAATTTTTA
GAGAATAAGATTGTTCATTGCATTTCTGAGTATTATGTAACCTATTTTTGCAGAAGGTACTGTTACATTAAGTGCATCTGTGTATCCTGG
TTTAAAAAAATGTAATCTTTTTTGAAATAAACCTTCATATTCTGTATAGTTGCTAAAGTGTTGAGAACCTTTTTAATTGTAAAATGAGAA
CCGATTTTCAGTTTAGTGTAGCAGCACACTTGTTCAGGTTTGCATGGTATGAAACCAAATAGATTCATGAAACCTTGGCCATGAGGTTTG
TTTCACAAGGTTCTTAGACCGAGTTGTGCAGGTAAGTGCACTTTTAGGTAATCTGCACTGTTTGTTTGATGGATAAATTCCATCTCTGGG
AATTGTGTGGGTATTAATGTTTCCATGTTCCCAACTATGTTGAGAAGTGGAAAAAAACCCAGGTTCTAGATGGGTGAATCAGTTGGGTTT

>74699_74699_2_RNF111-SLTM_RNF111_chr15_59323901_ENST00000434298_SLTM_chr15_59209198_ENST00000380516_length(amino acids)=1244AA_BP=293
MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLV
VRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR
SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSS
TEGEEDLFVSASENHQNNPAVPSGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKR
AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAED
DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAES
GDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR
SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKS
EKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR
RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIR
IEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP
ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHP
REAGPNPSRPTSWKSEGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD

--------------------------------------------------------------
>74699_74699_3_RNF111-SLTM_RNF111_chr15_59323901_ENST00000557998_SLTM_chr15_59209198_ENST00000380516_length(transcript)=4976nt_BP=1167nt
TGGAGGGGAGAAAGAGGAAGGGCTGCGGCCGCGGAAGGCTGGGGTCGGTGACCGGCCGGTTATCTCTGGCTCGGTGGTGACTTAGGGTCT
GGGTCTCCGCAGACGATTTGTGTTTGGGCAAGGCATTCGTCTACCGACACACCCACAGCCTACAGTGAGGGAGTGTGGGTGAGGGGATTT
CTCTCCCACTTCCGACTCTCCCTAGAGTCTCAGGATGGGGGCTGAGGACCGAGGCGTGGGAGTGCGATTTGACAATGGAGTGATGAAGGC
TTTCCTTAAAGTTTCCCATGTCTCAATGGACTCCTGAATATAACGAGCTCTACACCTTAAAAGTGGATATGAAGAGTGAGATTCCTTCTG
ATGCACCAAAGACACAGGAGAGTCTGAAAGGGATCCTTTTGCATCCAGAGCCCATTGGGGCAGCCAAAAGTTTTCCTGCAGGAGTTGAGA
TGATTAATAGTAAAGTGGGGAATGAATTCTCTCACCTGTGTGATGATTCTCAAAAGCAAGAGAAGGAAATGAATGGTAACCAGCAAGAAC
AAGAAAAAAGTCTCGTTGTGAGGAAAAAACGCAAAAGCCAGCAGGCTGGCCCTTCGTATGTGCAGAATTGTGTTAAAGAAAACCAGGGAA
TATTAGGACTGAGGCAACACCTAGGGACACCAAGTGATGAAGATAATGATTCCTCTTTTAGTGATTGTCTTTCTTCTCCTTCATCTAGTC
TGCATTTTGGAGATTCTGATACTGTGACTTCAGATGAGGATAAAGAAGTCTCTGTAAGACATTCCCAGACCATTTTGAATGCTAAAAGTA
GAAGCCATAGTGCACGGTCTCATAAGTGGCCTCGGACTGAGACAGAATCTGTATCGGGATTGTTAATGAAAAGACCCTGTTTACATGGCA
GTTCGTTACGGAGACTTCCATGCAGAAAGAGATTTGTAAAAAATAATTCCTCACAGAGGACACAGAAACAAAAAGAGAGGATATTAATGC
AGAGGAAGAAACGAGAAGTGTTAGCTCGAAGAAAATATGCCTTGCTACCTAGTTCTAGTAGTTCCAGTGAGAATGACCTCAGCAGTGAAT
CCTCTTCTAGCTCATCAACTGAAGGAGAAGAAGATTTGTTTGTTTCTGCCAGTGAAAACCACCAAAACAATCCAGCTGTTCCCTCAGGTA
AAAAACATGAAGCAGATGAGTTGAGTGGAGATGCTTCTGTGGAAGATGATGCTTTTATCAAGGACTGTGAATTGGAGAATCAAGAGGCAC
ATGAGCAAGATGGAAATGATGAACTAAAGGACTCTGAAGAATTTGGTGAAAATGAAGAAGAAAATGTGCATTCCAAGGAGTTACTCTCTG
CAGAAGAAAACAAGAGAGCTCATGAATTAATAGAGGCAGAAGGAATAGAAGATATAGAAAAAGAGGACATCGAAAGTCAGGAAATTGAAG
CTCAAGAAGGTGAAGATGATACCTTTCTAACAGCCCAAGATGGTGAGGAAGAAGAAAATGAGAAAGATATAGCAGGTTCTGGTGATGGTA
CACAAGAAGTATCTAAACCTCTTCCTTCAGAAGGGAGCCTAGCTGAGGCTGATCACACAGCTCATGAAGAGATGGAAGCTCATACGACTG
TGAAAGAAGCTGAGGATGACAACATCTCGGTCACAATCCAGGCTGAAGATGCCATCACTCTGGATTTTGATGGTGATGACCTCCTAGAAA
CAGGTAAAAATGTGAAAATTACAGATTCTGAAGCAAGTAAGCCAAAAGATGGGCAGGACGCCATTGCACAGAGCCCGGAGAAGGAAAGCA
AGGATTATGAGATGAATGCGAACCATAAAGATGGTAAGAAGGAAGACTGCGTGAAGGGTGACCCTGTCGAGAAGGAAGCCAGAGAAAGTT
CTAAGAAAGCAGAATCTGGAGACAAAGAAAAGGATACTTTGAAGAAAGGGCCCTCGTCTACTGGGGCCTCTGGTCAAGCAAAGAGCTCTT
CAAAGGAATCTAAAGACAGCAAGACATCATCTAAAGATGACAAAGGAAGTACAAGTAGTACTAGTGGTAGCAGTGGAAGCTCAACTAAAA
ATATCTGGGTTAGTGGACTTTCATCTAATACCAAAGCTGCTGATTTGAAGAACCTCTTTGGCAAATATGGAAAGGTTCTGAGTGCAAAAG
TAGTTACAAATGCTCGAAGTCCTGGGGCAAAATGCTATGGCATTGTAACTATGTCTTCAAGCACAGAGGTGTCCAGGTGTATTGCACATC
TTCATCGCACTGAGCTGCATGGACAGCTGATTTCTGTTGAAAAAGTAAAAGGTGATCCCTCTAAGAAAGAAATGAAGAAAGAAAATGATG
AAAAGAGTAGTTCAAGAAGTTCTGGAGATAAAAAAAATACGAGTGATAGAAGTAGCAAGACACAAGCCTCTGTCAAAAAAGAAGAGAAAA
GATCGTCTGAGAAATCTGAAAAAAAAGAAAGCAAGGATACTAAGAAAATAGAAGGTAAAGATGAGAAGAATGATAATGGAGCAAGTGGCC
AAACATCAGAATCGATTAAAAAAAGTGAAGAAAAGAAGCGAATAAGTTCCAAGAGTCCAGGACATATGGTAATACTAGACCAAACTAAAG
GAGATCATTGTAGACCATCAAGAAGAGGAAGATATGAGAAAATTCATGGAAGAAGTAAGGAAAAGGAGAGAGCTAGTCTAGATAAAAAAA
GAGATAAAGACTACAGAAGGAAAGAGATCTTGCCTTTTGAAAAGATGAAGGAACAAAGGTTGAGAGAACATTTAGTTCGTTTTGAAAGGC
TGCGACGAGCAATGGAACTTCGAAGACGAAGAGAGATTGCAGAGAGAGAGCGTCGAGAGCGAGAACGCATTAGAATAATTCGTGAACGGG
AAGAACGGGAACGCTTACAGAGAGAGAGAGAGCGCCTAGAAATTGAAAGGCAAAAACTAGAGAGAGAGAGAATGGAACGCGAACGCTTGG
AAAGGGAACGCATTCGTATTGAACAGGAACGTCGTAAGGAAGCTGAACGGATTGCTCGAGAAAGAGAGGAACTCAGAAGGCAACAACAGC
AGCTTCGTTATGAACAAGAAAAAAGGAATTCCTTGAAACGCCCACGTGATGTAGATCATAGGCGAGATGATCCTTACTGGAGCGAGAATA
AAAAGTTGTCTCTAGATACAGATGCACGATTTGGCCATGGATCCGACTACTCTCGCCAACAGAACAGATTTAATGACTTTGATCACCGAG
AGAGGGGCAGGTTTCCTGAGAGTTCAGCAGTACAGTCTTCATCTTTTGAAAGGCGGGATCGCTTTGTTGGTCAAAGTGAGGGGAAAAAAG
CACGACCTACTGCACGAAGGGAAGATCCAAGCTTCGAAAGATATCCCAAAAATTTCAGTGACTCCAGAAGAAATGAGCCTCCACCACCAA
GAAATGAACTTAGAGAATCAGACAGGCGAGAAGTACGAGGGGAGCGAGACGAAAGGAGAACGGTGATTATTCATGACAGGCCTGATATCA
CTCATCCTAGACATCCTCGAGAGGCAGGGCCCAATCCTTCCAGACCCACCAGCTGGAAAAGTGAAGGAAGCATGTCCACTGACAAACGGG
AAACAAGAGTTGAAAGGCCAGAACGATCTGGGAGAGAAGTATCAGGGCACAGTGTGAGAGGCGCTCCCCCTGGGAATCGTAGCAGCGCTT
CGGGGTACGGGAGCAGAGAGGGAGACAGAGGAGTCATCACAGACCGAGGAGGTGGATCACAGCACTATCCTGAGGAGCGACATGTGGTTG
AACGCCATGGACGGGACACAAGCGGACCAAGGAAAGAGTGGCATGGTCCACCCTCTCAAGGGCCTAGCTATCATGATACGAGGCGAATGG
GTGACGGCCGGGCAGGAGCAGGCATGATAACCCAACATTCAAGTAACGCATCCCCAATTAATAGAATTGTACAAATCAGTGGCAATTCCA
TGCCAAGAGGAAGTGGCTCCGGATTTAAGCCATTTAAGGGTGGACCTCCGCGACGATTCTGAAAATGAGCTCTCTGCCAAGGTTTTAAGA
TAATTTATTGAAATCTCCTGTAAACTTTACTTGACTACTTATGAAGAGGACCTCTGACTTGCTTGAGAGTTCTGTCAGACTTTTCTTTTT
AAAAATTTAACATGATTGCTTTTCTCAATTTTGGAGAAGATGTTTAAATAGTTCTGTTGTAACTTTTAATAGTTTTGTGTATCATTCAAC
TTTTTTTCTTGCAGCACCGAGGCACATTTGAAAAGATGGAATTGAAGTCGTTTTGTTTAACGCTGTGTGAATATAAAGAGTAGTTTGCAG
CTGTGTGGTAGTGGTTTAATTTGCAGCCTTAGCTCTGTGGTGTCTGGCTCTAGAGTTACTTCTTTTTACCAAGCATTTTCAGCCTCCATT
TTGAAGGCTGTCTACACTTAAGAAGTCTTAGCTGTCTAATTTTTAGAGAATAAGATTGTTCATTGCATTTCTGAGTATTATGTAACCTAT
TTTTGCAGAAGGTACTGTTACATTAAGTGCATCTGTGTATCCTGGTTTAAAAAAATGTAATCTTTTTTGAAATAAACCTTCATATTCTGT
ATAGTTGCTAAAGTGTTGAGAACCTTTTTAATTGTAAAATGAGAACCGATTTTCAGTTTAGTGTAGCAGCACACTTGTTCAGGTTTGCAT
GGTATGAAACCAAATAGATTCATGAAACCTTGGCCATGAGGTTTGTTTCACAAGGTTCTTAGACCGAGTTGTGCAGGTAAGTGCACTTTT
AGGTAATCTGCACTGTTTGTTTGATGGATAAATTCCATCTCTGGGAATTGTGTGGGTATTAATGTTTCCATGTTCCCAACTATGTTGAGA
AGTGGAAAAAAACCCAGGTTCTAGATGGGTGAATCAGTTGGGTTTTGTAAATACTTGTATGTGGGGAAGACATTGTTGTCTTTTTGTGAA

>74699_74699_3_RNF111-SLTM_RNF111_chr15_59323901_ENST00000557998_SLTM_chr15_59209198_ENST00000380516_length(amino acids)=1244AA_BP=293
MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLV
VRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR
SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSS
TEGEEDLFVSASENHQNNPAVPSGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKR
AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAED
DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAES
GDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR
SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKS
EKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR
RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIR
IEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP
ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHP
REAGPNPSRPTSWKSEGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD

--------------------------------------------------------------
>74699_74699_4_RNF111-SLTM_RNF111_chr15_59323901_ENST00000559209_SLTM_chr15_59209198_ENST00000380516_length(transcript)=4825nt_BP=1016nt
CTGAGGCGCAGATCGCTGGCTCTCGACGCATTACTCTTTACGCCTTACATTTCTGTCTTCCTTCCTGGGTCAGTGATTCCCGGACCCTGG
AAGAGAAGAGGGTGGCTAATGATTAAGGCTTTCCTTAAAGTTTCCCATGTCTCAATGGACTCCTGAATATAACGAGCTCTACACCTTAAA
AGTGGATATGAAGAGTGAGATTCCTTCTGATGCACCAAAGACACAGGAGAGTCTGAAAGGGATCCTTTTGCATCCAGAGCCCATTGGGGC
AGCCAAAAGTTTTCCTGCAGGAGTTGAGATGATTAATAGTAAAGTGGGGAATGAATTCTCTCACCTGTGTGATGATTCTCAAAAGCAAGA
GAAGGAAATGAATGGTAACCAGCAAGAACAAGAAAAAAGTCTCGTTGTGAGGAAAAAACGCAAAAGCCAGCAGGCTGGCCCTTCGTATGT
GCAGAATTGTGTTAAAGAAAACCAGGGAATATTAGGACTGAGGCAACACCTAGGGACACCAAGTGATGAAGATAATGATTCCTCTTTTAG
TGATTGTCTTTCTTCTCCTTCATCTAGTCTGCATTTTGGAGATTCTGATACTGTGACTTCAGATGAGGATAAAGAAGTCTCTGTAAGACA
TTCCCAGACCATTTTGAATGCTAAAAGTAGAAGCCATAGTGCACGGTCTCATAAGTGGCCTCGGACTGAGACAGAATCTGTATCGGGATT
GTTAATGAAAAGACCCTGTTTACATGGCAGTTCGTTACGGAGACTTCCATGCAGAAAGAGATTTGTAAAAAATAATTCCTCACAGAGGAC
ACAGAAACAAAAAGAGAGGATATTAATGCAGAGGAAGAAACGAGAAGTGTTAGCTCGAAGAAAATATGCCTTGCTACCTAGTTCTAGTAG
TTCCAGTGAGAATGACCTCAGCAGTGAATCCTCTTCTAGCTCATCAACTGAAGGAGAAGAAGATTTGTTTGTTTCTGCCAGTGAAAACCA
CCAAAACAATCCAGCTGTTCCCTCAGGTAAAAAACATGAAGCAGATGAGTTGAGTGGAGATGCTTCTGTGGAAGATGATGCTTTTATCAA
GGACTGTGAATTGGAGAATCAAGAGGCACATGAGCAAGATGGAAATGATGAACTAAAGGACTCTGAAGAATTTGGTGAAAATGAAGAAGA
AAATGTGCATTCCAAGGAGTTACTCTCTGCAGAAGAAAACAAGAGAGCTCATGAATTAATAGAGGCAGAAGGAATAGAAGATATAGAAAA
AGAGGACATCGAAAGTCAGGAAATTGAAGCTCAAGAAGGTGAAGATGATACCTTTCTAACAGCCCAAGATGGTGAGGAAGAAGAAAATGA
GAAAGATATAGCAGGTTCTGGTGATGGTACACAAGAAGTATCTAAACCTCTTCCTTCAGAAGGGAGCCTAGCTGAGGCTGATCACACAGC
TCATGAAGAGATGGAAGCTCATACGACTGTGAAAGAAGCTGAGGATGACAACATCTCGGTCACAATCCAGGCTGAAGATGCCATCACTCT
GGATTTTGATGGTGATGACCTCCTAGAAACAGGTAAAAATGTGAAAATTACAGATTCTGAAGCAAGTAAGCCAAAAGATGGGCAGGACGC
CATTGCACAGAGCCCGGAGAAGGAAAGCAAGGATTATGAGATGAATGCGAACCATAAAGATGGTAAGAAGGAAGACTGCGTGAAGGGTGA
CCCTGTCGAGAAGGAAGCCAGAGAAAGTTCTAAGAAAGCAGAATCTGGAGACAAAGAAAAGGATACTTTGAAGAAAGGGCCCTCGTCTAC
TGGGGCCTCTGGTCAAGCAAAGAGCTCTTCAAAGGAATCTAAAGACAGCAAGACATCATCTAAAGATGACAAAGGAAGTACAAGTAGTAC
TAGTGGTAGCAGTGGAAGCTCAACTAAAAATATCTGGGTTAGTGGACTTTCATCTAATACCAAAGCTGCTGATTTGAAGAACCTCTTTGG
CAAATATGGAAAGGTTCTGAGTGCAAAAGTAGTTACAAATGCTCGAAGTCCTGGGGCAAAATGCTATGGCATTGTAACTATGTCTTCAAG
CACAGAGGTGTCCAGGTGTATTGCACATCTTCATCGCACTGAGCTGCATGGACAGCTGATTTCTGTTGAAAAAGTAAAAGGTGATCCCTC
TAAGAAAGAAATGAAGAAAGAAAATGATGAAAAGAGTAGTTCAAGAAGTTCTGGAGATAAAAAAAATACGAGTGATAGAAGTAGCAAGAC
ACAAGCCTCTGTCAAAAAAGAAGAGAAAAGATCGTCTGAGAAATCTGAAAAAAAAGAAAGCAAGGATACTAAGAAAATAGAAGGTAAAGA
TGAGAAGAATGATAATGGAGCAAGTGGCCAAACATCAGAATCGATTAAAAAAAGTGAAGAAAAGAAGCGAATAAGTTCCAAGAGTCCAGG
ACATATGGTAATACTAGACCAAACTAAAGGAGATCATTGTAGACCATCAAGAAGAGGAAGATATGAGAAAATTCATGGAAGAAGTAAGGA
AAAGGAGAGAGCTAGTCTAGATAAAAAAAGAGATAAAGACTACAGAAGGAAAGAGATCTTGCCTTTTGAAAAGATGAAGGAACAAAGGTT
GAGAGAACATTTAGTTCGTTTTGAAAGGCTGCGACGAGCAATGGAACTTCGAAGACGAAGAGAGATTGCAGAGAGAGAGCGTCGAGAGCG
AGAACGCATTAGAATAATTCGTGAACGGGAAGAACGGGAACGCTTACAGAGAGAGAGAGAGCGCCTAGAAATTGAAAGGCAAAAACTAGA
GAGAGAGAGAATGGAACGCGAACGCTTGGAAAGGGAACGCATTCGTATTGAACAGGAACGTCGTAAGGAAGCTGAACGGATTGCTCGAGA
AAGAGAGGAACTCAGAAGGCAACAACAGCAGCTTCGTTATGAACAAGAAAAAAGGAATTCCTTGAAACGCCCACGTGATGTAGATCATAG
GCGAGATGATCCTTACTGGAGCGAGAATAAAAAGTTGTCTCTAGATACAGATGCACGATTTGGCCATGGATCCGACTACTCTCGCCAACA
GAACAGATTTAATGACTTTGATCACCGAGAGAGGGGCAGGTTTCCTGAGAGTTCAGCAGTACAGTCTTCATCTTTTGAAAGGCGGGATCG
CTTTGTTGGTCAAAGTGAGGGGAAAAAAGCACGACCTACTGCACGAAGGGAAGATCCAAGCTTCGAAAGATATCCCAAAAATTTCAGTGA
CTCCAGAAGAAATGAGCCTCCACCACCAAGAAATGAACTTAGAGAATCAGACAGGCGAGAAGTACGAGGGGAGCGAGACGAAAGGAGAAC
GGTGATTATTCATGACAGGCCTGATATCACTCATCCTAGACATCCTCGAGAGGCAGGGCCCAATCCTTCCAGACCCACCAGCTGGAAAAG
TGAAGGAAGCATGTCCACTGACAAACGGGAAACAAGAGTTGAAAGGCCAGAACGATCTGGGAGAGAAGTATCAGGGCACAGTGTGAGAGG
CGCTCCCCCTGGGAATCGTAGCAGCGCTTCGGGGTACGGGAGCAGAGAGGGAGACAGAGGAGTCATCACAGACCGAGGAGGTGGATCACA
GCACTATCCTGAGGAGCGACATGTGGTTGAACGCCATGGACGGGACACAAGCGGACCAAGGAAAGAGTGGCATGGTCCACCCTCTCAAGG
GCCTAGCTATCATGATACGAGGCGAATGGGTGACGGCCGGGCAGGAGCAGGCATGATAACCCAACATTCAAGTAACGCATCCCCAATTAA
TAGAATTGTACAAATCAGTGGCAATTCCATGCCAAGAGGAAGTGGCTCCGGATTTAAGCCATTTAAGGGTGGACCTCCGCGACGATTCTG
AAAATGAGCTCTCTGCCAAGGTTTTAAGATAATTTATTGAAATCTCCTGTAAACTTTACTTGACTACTTATGAAGAGGACCTCTGACTTG
CTTGAGAGTTCTGTCAGACTTTTCTTTTTAAAAATTTAACATGATTGCTTTTCTCAATTTTGGAGAAGATGTTTAAATAGTTCTGTTGTA
ACTTTTAATAGTTTTGTGTATCATTCAACTTTTTTTCTTGCAGCACCGAGGCACATTTGAAAAGATGGAATTGAAGTCGTTTTGTTTAAC
GCTGTGTGAATATAAAGAGTAGTTTGCAGCTGTGTGGTAGTGGTTTAATTTGCAGCCTTAGCTCTGTGGTGTCTGGCTCTAGAGTTACTT
CTTTTTACCAAGCATTTTCAGCCTCCATTTTGAAGGCTGTCTACACTTAAGAAGTCTTAGCTGTCTAATTTTTAGAGAATAAGATTGTTC
ATTGCATTTCTGAGTATTATGTAACCTATTTTTGCAGAAGGTACTGTTACATTAAGTGCATCTGTGTATCCTGGTTTAAAAAAATGTAAT
CTTTTTTGAAATAAACCTTCATATTCTGTATAGTTGCTAAAGTGTTGAGAACCTTTTTAATTGTAAAATGAGAACCGATTTTCAGTTTAG
TGTAGCAGCACACTTGTTCAGGTTTGCATGGTATGAAACCAAATAGATTCATGAAACCTTGGCCATGAGGTTTGTTTCACAAGGTTCTTA
GACCGAGTTGTGCAGGTAAGTGCACTTTTAGGTAATCTGCACTGTTTGTTTGATGGATAAATTCCATCTCTGGGAATTGTGTGGGTATTA
ATGTTTCCATGTTCCCAACTATGTTGAGAAGTGGAAAAAAACCCAGGTTCTAGATGGGTGAATCAGTTGGGTTTTGTAAATACTTGTATG

>74699_74699_4_RNF111-SLTM_RNF111_chr15_59323901_ENST00000559209_SLTM_chr15_59209198_ENST00000380516_length(amino acids)=1244AA_BP=293
MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLV
VRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR
SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSS
TEGEEDLFVSASENHQNNPAVPSGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKR
AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAED
DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAES
GDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR
SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKS
EKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR
RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIR
IEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP
ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHP
REAGPNPSRPTSWKSEGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD

--------------------------------------------------------------
>74699_74699_5_RNF111-SLTM_RNF111_chr15_59323901_ENST00000561186_SLTM_chr15_59209198_ENST00000380516_length(transcript)=4689nt_BP=880nt
ATGTCTCAATGGACTCCTGAATATAACGAGCTCTACACCTTAAAAGTGGATATGAAGAGTGAGATTCCTTCTGATGCACCAAAGACACAG
GAGAGTCTGAAAGGGATCCTTTTGCATCCAGAGCCCATTGGGGCAGCCAAAAGTTTTCCTGCAGGAGTTGAGATGATTAATAGTAAAGTG
GGGAATGAATTCTCTCACCTGTGTGATGATTCTCAAAAGCAAGAGAAGGAAATGAATGGTAACCAGCAAGAACAAGAAAAAAGTCTCGTT
GTGAGGAAAAAACGCAAAAGCCAGCAGGCTGGCCCTTCGTATGTGCAGAATTGTGTTAAAGAAAACCAGGGAATATTAGGACTGAGGCAA
CACCTAGGGACACCAAGTGATGAAGATAATGATTCCTCTTTTAGTGATTGTCTTTCTTCTCCTTCATCTAGTCTGCATTTTGGAGATTCT
GATACTGTGACTTCAGATGAGGATAAAGAAGTCTCTGTAAGACATTCCCAGACCATTTTGAATGCTAAAAGTAGAAGCCATAGTGCACGG
TCTCATAAGTGGCCTCGGACTGAGACAGAATCTGTATCGGGATTGTTAATGAAAAGACCCTGTTTACATGGCAGTTCGTTACGGAGACTT
CCATGCAGAAAGAGATTTGTAAAAAATAATTCCTCACAGAGGACACAGAAACAAAAAGAGAGGATATTAATGCAGAGGAAGAAACGAGAA
GTGTTAGCTCGAAGAAAATATGCCTTGCTACCTAGTTCTAGTAGTTCCAGTGAGAATGACCTCAGCAGTGAATCCTCTTCTAGCTCATCA
ACTGAAGGAGAAGAAGATTTGTTTGTTTCTGCCAGTGAAAACCACCAAAACAATCCAGCTGTTCCCTCAGGTAAAAAACATGAAGCAGAT
GAGTTGAGTGGAGATGCTTCTGTGGAAGATGATGCTTTTATCAAGGACTGTGAATTGGAGAATCAAGAGGCACATGAGCAAGATGGAAAT
GATGAACTAAAGGACTCTGAAGAATTTGGTGAAAATGAAGAAGAAAATGTGCATTCCAAGGAGTTACTCTCTGCAGAAGAAAACAAGAGA
GCTCATGAATTAATAGAGGCAGAAGGAATAGAAGATATAGAAAAAGAGGACATCGAAAGTCAGGAAATTGAAGCTCAAGAAGGTGAAGAT
GATACCTTTCTAACAGCCCAAGATGGTGAGGAAGAAGAAAATGAGAAAGATATAGCAGGTTCTGGTGATGGTACACAAGAAGTATCTAAA
CCTCTTCCTTCAGAAGGGAGCCTAGCTGAGGCTGATCACACAGCTCATGAAGAGATGGAAGCTCATACGACTGTGAAAGAAGCTGAGGAT
GACAACATCTCGGTCACAATCCAGGCTGAAGATGCCATCACTCTGGATTTTGATGGTGATGACCTCCTAGAAACAGGTAAAAATGTGAAA
ATTACAGATTCTGAAGCAAGTAAGCCAAAAGATGGGCAGGACGCCATTGCACAGAGCCCGGAGAAGGAAAGCAAGGATTATGAGATGAAT
GCGAACCATAAAGATGGTAAGAAGGAAGACTGCGTGAAGGGTGACCCTGTCGAGAAGGAAGCCAGAGAAAGTTCTAAGAAAGCAGAATCT
GGAGACAAAGAAAAGGATACTTTGAAGAAAGGGCCCTCGTCTACTGGGGCCTCTGGTCAAGCAAAGAGCTCTTCAAAGGAATCTAAAGAC
AGCAAGACATCATCTAAAGATGACAAAGGAAGTACAAGTAGTACTAGTGGTAGCAGTGGAAGCTCAACTAAAAATATCTGGGTTAGTGGA
CTTTCATCTAATACCAAAGCTGCTGATTTGAAGAACCTCTTTGGCAAATATGGAAAGGTTCTGAGTGCAAAAGTAGTTACAAATGCTCGA
AGTCCTGGGGCAAAATGCTATGGCATTGTAACTATGTCTTCAAGCACAGAGGTGTCCAGGTGTATTGCACATCTTCATCGCACTGAGCTG
CATGGACAGCTGATTTCTGTTGAAAAAGTAAAAGGTGATCCCTCTAAGAAAGAAATGAAGAAAGAAAATGATGAAAAGAGTAGTTCAAGA
AGTTCTGGAGATAAAAAAAATACGAGTGATAGAAGTAGCAAGACACAAGCCTCTGTCAAAAAAGAAGAGAAAAGATCGTCTGAGAAATCT
GAAAAAAAAGAAAGCAAGGATACTAAGAAAATAGAAGGTAAAGATGAGAAGAATGATAATGGAGCAAGTGGCCAAACATCAGAATCGATT
AAAAAAAGTGAAGAAAAGAAGCGAATAAGTTCCAAGAGTCCAGGACATATGGTAATACTAGACCAAACTAAAGGAGATCATTGTAGACCA
TCAAGAAGAGGAAGATATGAGAAAATTCATGGAAGAAGTAAGGAAAAGGAGAGAGCTAGTCTAGATAAAAAAAGAGATAAAGACTACAGA
AGGAAAGAGATCTTGCCTTTTGAAAAGATGAAGGAACAAAGGTTGAGAGAACATTTAGTTCGTTTTGAAAGGCTGCGACGAGCAATGGAA
CTTCGAAGACGAAGAGAGATTGCAGAGAGAGAGCGTCGAGAGCGAGAACGCATTAGAATAATTCGTGAACGGGAAGAACGGGAACGCTTA
CAGAGAGAGAGAGAGCGCCTAGAAATTGAAAGGCAAAAACTAGAGAGAGAGAGAATGGAACGCGAACGCTTGGAAAGGGAACGCATTCGT
ATTGAACAGGAACGTCGTAAGGAAGCTGAACGGATTGCTCGAGAAAGAGAGGAACTCAGAAGGCAACAACAGCAGCTTCGTTATGAACAA
GAAAAAAGGAATTCCTTGAAACGCCCACGTGATGTAGATCATAGGCGAGATGATCCTTACTGGAGCGAGAATAAAAAGTTGTCTCTAGAT
ACAGATGCACGATTTGGCCATGGATCCGACTACTCTCGCCAACAGAACAGATTTAATGACTTTGATCACCGAGAGAGGGGCAGGTTTCCT
GAGAGTTCAGCAGTACAGTCTTCATCTTTTGAAAGGCGGGATCGCTTTGTTGGTCAAAGTGAGGGGAAAAAAGCACGACCTACTGCACGA
AGGGAAGATCCAAGCTTCGAAAGATATCCCAAAAATTTCAGTGACTCCAGAAGAAATGAGCCTCCACCACCAAGAAATGAACTTAGAGAA
TCAGACAGGCGAGAAGTACGAGGGGAGCGAGACGAAAGGAGAACGGTGATTATTCATGACAGGCCTGATATCACTCATCCTAGACATCCT
CGAGAGGCAGGGCCCAATCCTTCCAGACCCACCAGCTGGAAAAGTGAAGGAAGCATGTCCACTGACAAACGGGAAACAAGAGTTGAAAGG
CCAGAACGATCTGGGAGAGAAGTATCAGGGCACAGTGTGAGAGGCGCTCCCCCTGGGAATCGTAGCAGCGCTTCGGGGTACGGGAGCAGA
GAGGGAGACAGAGGAGTCATCACAGACCGAGGAGGTGGATCACAGCACTATCCTGAGGAGCGACATGTGGTTGAACGCCATGGACGGGAC
ACAAGCGGACCAAGGAAAGAGTGGCATGGTCCACCCTCTCAAGGGCCTAGCTATCATGATACGAGGCGAATGGGTGACGGCCGGGCAGGA
GCAGGCATGATAACCCAACATTCAAGTAACGCATCCCCAATTAATAGAATTGTACAAATCAGTGGCAATTCCATGCCAAGAGGAAGTGGC
TCCGGATTTAAGCCATTTAAGGGTGGACCTCCGCGACGATTCTGAAAATGAGCTCTCTGCCAAGGTTTTAAGATAATTTATTGAAATCTC
CTGTAAACTTTACTTGACTACTTATGAAGAGGACCTCTGACTTGCTTGAGAGTTCTGTCAGACTTTTCTTTTTAAAAATTTAACATGATT
GCTTTTCTCAATTTTGGAGAAGATGTTTAAATAGTTCTGTTGTAACTTTTAATAGTTTTGTGTATCATTCAACTTTTTTTCTTGCAGCAC
CGAGGCACATTTGAAAAGATGGAATTGAAGTCGTTTTGTTTAACGCTGTGTGAATATAAAGAGTAGTTTGCAGCTGTGTGGTAGTGGTTT
AATTTGCAGCCTTAGCTCTGTGGTGTCTGGCTCTAGAGTTACTTCTTTTTACCAAGCATTTTCAGCCTCCATTTTGAAGGCTGTCTACAC
TTAAGAAGTCTTAGCTGTCTAATTTTTAGAGAATAAGATTGTTCATTGCATTTCTGAGTATTATGTAACCTATTTTTGCAGAAGGTACTG
TTACATTAAGTGCATCTGTGTATCCTGGTTTAAAAAAATGTAATCTTTTTTGAAATAAACCTTCATATTCTGTATAGTTGCTAAAGTGTT
GAGAACCTTTTTAATTGTAAAATGAGAACCGATTTTCAGTTTAGTGTAGCAGCACACTTGTTCAGGTTTGCATGGTATGAAACCAAATAG
ATTCATGAAACCTTGGCCATGAGGTTTGTTTCACAAGGTTCTTAGACCGAGTTGTGCAGGTAAGTGCACTTTTAGGTAATCTGCACTGTT
TGTTTGATGGATAAATTCCATCTCTGGGAATTGTGTGGGTATTAATGTTTCCATGTTCCCAACTATGTTGAGAAGTGGAAAAAAACCCAG
GTTCTAGATGGGTGAATCAGTTGGGTTTTGTAAATACTTGTATGTGGGGAAGACATTGTTGTCTTTTTGTGAAAATAAAAATCCACACCT

>74699_74699_5_RNF111-SLTM_RNF111_chr15_59323901_ENST00000561186_SLTM_chr15_59209198_ENST00000380516_length(amino acids)=1244AA_BP=293
MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLV
VRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR
SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSS
TEGEEDLFVSASENHQNNPAVPSGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKR
AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAED
DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAES
GDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR
SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKS
EKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR
RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIR
IEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP
ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHP
REAGPNPSRPTSWKSEGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD

--------------------------------------------------------------
>74699_74699_6_RNF111-SLTM_RNF111_chr15_59359282_ENST00000348370_SLTM_chr15_59193486_ENST00000380516_length(transcript)=5617nt_BP=2119nt
AGAGCCCTAGTGTCGTGCTCTCCTCGGTAGGGGAGGAATTGGTTAGGCGGCGGCGGCGGCGAAGCGGCGGCGGCGGCTGTAGGGGAGCAG
CGGCAGTGGCGGCGACGGCGAGGAGGTGTTCGGTTTGCGCAGCGTAGAAACGCCCGCAGCTTCAGAGAAGGAGTTCTTGTGGGACCAAAT
TAGGCATTCTGAACCCACGCCGGCTTAGCTGGGCCGAGTCCAGGCGCTGCCGCACGTACAGTTTTGGTGGCGGTGACAGACACTGTTCTT
GACTCTAGGGGCCTATTAGGCCGACGTCTGAGGCGCAGATCGCTGGCTCTCGACGCATTACTCTTTACGCCTTACATTTCTGTCTTCCTT
CCTGGGTCAGTGATTCCCGGACCCTGGAAGAGAAGAGGGTGGCTAATGATTAAGGCTTTCCTTAAAGTTTCCCATGTCTCAATGGACTCC
TGAATATAACGAGCTCTACACCTTAAAAGTGGATATGAAGAGTGAGATTCCTTCTGATGCACCAAAGACACAGGAGAGTCTGAAAGGGAT
CCTTTTGCATCCAGAGCCCATTGGGGCAGCCAAAAGTTTTCCTGCAGGAGTTGAGATGATTAATAGTAAAGTGGGGAATGAATTCTCTCA
CCTGTGTGATGATTCTCAAAAGCAAGAGAAGGAAATGAATGGTAACCAGCAAGAACAAGAAAAAAGTCTCGTTGTGAGGAAAAAACGCAA
AAGCCAGCAGGCTGGCCCTTCGTATGTGCAGAATTGTGTTAAAGAAAACCAGGGAATATTAGGACTGAGGCAACACCTAGGGACACCAAG
TGATGAAGATAATGATTCCTCTTTTAGTGATTGTCTTTCTTCTCCTTCATCTAGTCTGCATTTTGGAGATTCTGATACTGTGACTTCAGA
TGAGGATAAAGAAGTCTCTGTAAGACATTCCCAGACCATTTTGAATGCTAAAAGTAGAAGCCATAGTGCACGGTCTCATAAGTGGCCTCG
GACTGAGACAGAATCTGTATCGGGATTGTTAATGAAAAGACCCTGTTTACATGGCAGTTCGTTACGGAGACTTCCATGCAGAAAGAGATT
TGTAAAAAATAATTCCTCACAGAGGACACAGAAACAAAAAGAGAGGATATTAATGCAGAGGAAGAAACGAGAAGTGTTAGCTCGAAGAAA
ATATGCCTTGCTACCTAGTTCTAGTAGTTCCAGTGAGAATGACCTCAGCAGTGAATCCTCTTCTAGCTCATCAACTGAAGGAGAAGAAGA
TTTGTTTGTTTCTGCCAGTGAAAACCACCAAAACAATCCAGCTGTTCCCTCAGGAAGTATTGATGAAGATGTTGTGGTGATAGAAGCTTC
CTCCACTCCCCAGGTTACTGCCAATGAAGAAATTAATGTTACCTCAACTGACAGTGAAGTGGAGATTGTAACAGTTGGAGAAAGCTATCG
GTCTCGTTCAACCCTTGGACACTCCAGATCTCATTGGAGCCAGGGTTCCAGTTCTCATGCAAGTCGGCCACAGGAGCCACGGAACCGCAG
TAGGATTTCTACTGTTATACAGCCCTTGAGGCAGAATGCAGCAGAAGTTGTGGACCTTACCGTTGATGAAGATGAACCTACTGTAGTACC
AACCACTTCTGCAAGAATGGAATCACAAGCTACTAGCGCTTCCATTAACAATTCAAATCCATCTACCTCTGAGCAGGCCTCTGATACTGC
TTCAGCTGTCACCAGTAGCCAACCTTCCACAGTGTCAGAGACTTCAGCTACTCTTACAAGCAATAGTACCACTGGCACTTCTATAGGAGA
TGACTCAAGGAGAACTACATCTAGTGCTGTAACGGAAACTGGCCCTCCTGCAATGCCAAGGTTACCTTCCTGCTGTCCCCAGCACTCACC
ATGTGGAGGGTCGTCACAGAACCACCATGCATTAGGACATCCTCATACAAGTTGCTTTCAGCAGCATGGTCACCATTTTCAACATCATCA
CCACCACCACCATACTCCCCACCCAGCTGTCCCAGTTTCTCCTTCCTTTAGTGATCCTGCTTGCCCTGTGGAAAGACCTCCACAAGTACA
AGCACCTTGTGGAGCAAATAGTAGTTCTGGTACCAGCTATCATGAACAGGATGGTGAGGAAGAAGAAAATGAGAAAGATATAGCAGGTTC
TGGTGATGGTACACAAGAAGTATCTAAACCTCTTCCTTCAGAAGGGAGCCTAGCTGAGGCTGATCACACAGCTCATGAAGAGATGGAAGC
TCATACGACTGTGAAAGAAGCTGAGGATGACAACATCTCGGTCACAATCCAGGCTGAAGATGCCATCACTCTGGATTTTGATGGTGATGA
CCTCCTAGAAACAGGTAAAAATGTGAAAATTACAGATTCTGAAGCAAGTAAGCCAAAAGATGGGCAGGACGCCATTGCACAGAGCCCGGA
GAAGGAAAGCAAGGATTATGAGATGAATGCGAACCATAAAGATGGTAAGAAGGAAGACTGCGTGAAGGGTGACCCTGTCGAGAAGGAAGC
CAGAGAAAGTTCTAAGAAAGCAGAATCTGGAGACAAAGAAAAGGATACTTTGAAGAAAGGGCCCTCGTCTACTGGGGCCTCTGGTCAAGC
AAAGAGCTCTTCAAAGGAATCTAAAGACAGCAAGACATCATCTAAAGATGACAAAGGAAGTACAAGTAGTACTAGTGGTAGCAGTGGAAG
CTCAACTAAAAATATCTGGGTTAGTGGACTTTCATCTAATACCAAAGCTGCTGATTTGAAGAACCTCTTTGGCAAATATGGAAAGGTTCT
GAGTGCAAAAGTAGTTACAAATGCTCGAAGTCCTGGGGCAAAATGCTATGGCATTGTAACTATGTCTTCAAGCACAGAGGTGTCCAGGTG
TATTGCACATCTTCATCGCACTGAGCTGCATGGACAGCTGATTTCTGTTGAAAAAGTAAAAGGTGATCCCTCTAAGAAAGAAATGAAGAA
AGAAAATGATGAAAAGAGTAGTTCAAGAAGTTCTGGAGATAAAAAAAATACGAGTGATAGAAGTAGCAAGACACAAGCCTCTGTCAAAAA
AGAAGAGAAAAGATCGTCTGAGAAATCTGAAAAAAAAGAAAGCAAGGATACTAAGAAAATAGAAGGTAAAGATGAGAAGAATGATAATGG
AGCAAGTGGCCAAACATCAGAATCGATTAAAAAAAGTGAAGAAAAGAAGCGAATAAGTTCCAAGAGTCCAGGACATATGGTAATACTAGA
CCAAACTAAAGGAGATCATTGTAGACCATCAAGAAGAGGAAGATATGAGAAAATTCATGGAAGAAGTAAGGAAAAGGAGAGAGCTAGTCT
AGATAAAAAAAGAGATAAAGACTACAGAAGGAAAGAGATCTTGCCTTTTGAAAAGATGAAGGAACAAAGGTTGAGAGAACATTTAGTTCG
TTTTGAAAGGCTGCGACGAGCAATGGAACTTCGAAGACGAAGAGAGATTGCAGAGAGAGAGCGTCGAGAGCGAGAACGCATTAGAATAAT
TCGTGAACGGGAAGAACGGGAACGCTTACAGAGAGAGAGAGAGCGCCTAGAAATTGAAAGGCAAAAACTAGAGAGAGAGAGAATGGAACG
CGAACGCTTGGAAAGGGAACGCATTCGTATTGAACAGGAACGTCGTAAGGAAGCTGAACGGATTGCTCGAGAAAGAGAGGAACTCAGAAG
GCAACAACAGCAGCTTCGTTATGAACAAGAAAAAAGGAATTCCTTGAAACGCCCACGTGATGTAGATCATAGGCGAGATGATCCTTACTG
GAGCGAGAATAAAAAGTTGTCTCTAGATACAGATGCACGATTTGGCCATGGATCCGACTACTCTCGCCAACAGAACAGATTTAATGACTT
TGATCACCGAGAGAGGGGCAGGTTTCCTGAGAGTTCAGCAGTACAGTCTTCATCTTTTGAAAGGCGGGATCGCTTTGTTGGTCAAAGTGA
GGGGAAAAAAGCACGACCTACTGCACGAAGGGAAGATCCAAGCTTCGAAAGATATCCCAAAAATTTCAGTGACTCCAGAAGAAATGAGCC
TCCACCACCAAGAAATGAACTTAGAGAATCAGACAGGCGAGAAGTACGAGGGGAGCGAGACGAAAGGAGAACGGTGATTATTCATGACAG
GCCTGATATCACTCATCCTAGACATCCTCGAGAGGCAGGGCCCAATCCTTCCAGACCCACCAGCTGGAAAAGTGAAGGAAGCATGTCCAC
TGACAAACGGGAAACAAGAGTTGAAAGGCCAGAACGATCTGGGAGAGAAGTATCAGGGCACAGTGTGAGAGGCGCTCCCCCTGGGAATCG
TAGCAGCGCTTCGGGGTACGGGAGCAGAGAGGGAGACAGAGGAGTCATCACAGACCGAGGAGGTGGATCACAGCACTATCCTGAGGAGCG
ACATGTGGTTGAACGCCATGGACGGGACACAAGCGGACCAAGGAAAGAGTGGCATGGTCCACCCTCTCAAGGGCCTAGCTATCATGATAC
GAGGCGAATGGGTGACGGCCGGGCAGGAGCAGGCATGATAACCCAACATTCAAGTAACGCATCCCCAATTAATAGAATTGTACAAATCAG
TGGCAATTCCATGCCAAGAGGAAGTGGCTCCGGATTTAAGCCATTTAAGGGTGGACCTCCGCGACGATTCTGAAAATGAGCTCTCTGCCA
AGGTTTTAAGATAATTTATTGAAATCTCCTGTAAACTTTACTTGACTACTTATGAAGAGGACCTCTGACTTGCTTGAGAGTTCTGTCAGA
CTTTTCTTTTTAAAAATTTAACATGATTGCTTTTCTCAATTTTGGAGAAGATGTTTAAATAGTTCTGTTGTAACTTTTAATAGTTTTGTG
TATCATTCAACTTTTTTTCTTGCAGCACCGAGGCACATTTGAAAAGATGGAATTGAAGTCGTTTTGTTTAACGCTGTGTGAATATAAAGA
GTAGTTTGCAGCTGTGTGGTAGTGGTTTAATTTGCAGCCTTAGCTCTGTGGTGTCTGGCTCTAGAGTTACTTCTTTTTACCAAGCATTTT
CAGCCTCCATTTTGAAGGCTGTCTACACTTAAGAAGTCTTAGCTGTCTAATTTTTAGAGAATAAGATTGTTCATTGCATTTCTGAGTATT
ATGTAACCTATTTTTGCAGAAGGTACTGTTACATTAAGTGCATCTGTGTATCCTGGTTTAAAAAAATGTAATCTTTTTTGAAATAAACCT
TCATATTCTGTATAGTTGCTAAAGTGTTGAGAACCTTTTTAATTGTAAAATGAGAACCGATTTTCAGTTTAGTGTAGCAGCACACTTGTT
CAGGTTTGCATGGTATGAAACCAAATAGATTCATGAAACCTTGGCCATGAGGTTTGTTTCACAAGGTTCTTAGACCGAGTTGTGCAGGTA
AGTGCACTTTTAGGTAATCTGCACTGTTTGTTTGATGGATAAATTCCATCTCTGGGAATTGTGTGGGTATTAATGTTTCCATGTTCCCAA
CTATGTTGAGAAGTGGAAAAAAACCCAGGTTCTAGATGGGTGAATCAGTTGGGTTTTGTAAATACTTGTATGTGGGGAAGACATTGTTGT

>74699_74699_6_RNF111-SLTM_RNF111_chr15_59359282_ENST00000348370_SLTM_chr15_59193486_ENST00000380516_length(amino acids)=1409AA_BP=561
MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLV
VRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR
SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSS
TEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQ
EPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTT
GTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVE
RPPQVQAPCGANSSSGTSYHEQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITL
DFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSST
GASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSS
TEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKD
EKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRL
REHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARE
REELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDR
FVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKS
EGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPPSQG

--------------------------------------------------------------
>74699_74699_7_RNF111-SLTM_RNF111_chr15_59359282_ENST00000434298_SLTM_chr15_59193486_ENST00000380516_length(transcript)=5606nt_BP=2108nt
GTCGTGCTCTCCTCGGTAGGGGAGGAATTGGTTAGGCGGCGGCGGCGGCGAAGCGGCGGCGGCGGCTGTAGGGGAGCAGCGGCAGTGGCG
GCGACGGCGAGGAGGTGTTCGGTTTGCGCAGCGTAGAAACGCCCGCAGCTTCAGAGAAGGAGTTCTTGTGGGACCAAATTAGGCATTCTG
AACCCACGCCGGCTTAGCTGGGCCGAGTCCAGGCGCTGCCGCACGTACAGTTTTGGTGGCGGTGACAGACACTGTTCTTGACTCTAGGGG
CCTATTAGGCCGACGTCTGAGGCGCAGATCGCTGGCTCTCGACGCATTACTCTTTACGCCTTACATTTCTGTCTTCCTTCCTGGGTCAGT
GATTCCCGGACCCTGGAAGAGAAGAGGGTGGCTAATGATTAAGGCTTTCCTTAAAGTTTCCCATGTCTCAATGGACTCCTGAATATAACG
AGCTCTACACCTTAAAAGTGGATATGAAGAGTGAGATTCCTTCTGATGCACCAAAGACACAGGAGAGTCTGAAAGGGATCCTTTTGCATC
CAGAGCCCATTGGGGCAGCCAAAAGTTTTCCTGCAGGAGTTGAGATGATTAATAGTAAAGTGGGGAATGAATTCTCTCACCTGTGTGATG
ATTCTCAAAAGCAAGAGAAGGAAATGAATGGTAACCAGCAAGAACAAGAAAAAAGTCTCGTTGTGAGGAAAAAACGCAAAAGCCAGCAGG
CTGGCCCTTCGTATGTGCAGAATTGTGTTAAAGAAAACCAGGGAATATTAGGACTGAGGCAACACCTAGGGACACCAAGTGATGAAGATA
ATGATTCCTCTTTTAGTGATTGTCTTTCTTCTCCTTCATCTAGTCTGCATTTTGGAGATTCTGATACTGTGACTTCAGATGAGGATAAAG
AAGTCTCTGTAAGACATTCCCAGACCATTTTGAATGCTAAAAGTAGAAGCCATAGTGCACGGTCTCATAAGTGGCCTCGGACTGAGACAG
AATCTGTATCGGGATTGTTAATGAAAAGACCCTGTTTACATGGCAGTTCGTTACGGAGACTTCCATGCAGAAAGAGATTTGTAAAAAATA
ATTCCTCACAGAGGACACAGAAACAAAAAGAGAGGATATTAATGCAGAGGAAGAAACGAGAAGTGTTAGCTCGAAGAAAATATGCCTTGC
TACCTAGTTCTAGTAGTTCCAGTGAGAATGACCTCAGCAGTGAATCCTCTTCTAGCTCATCAACTGAAGGAGAAGAAGATTTGTTTGTTT
CTGCCAGTGAAAACCACCAAAACAATCCAGCTGTTCCCTCAGGAAGTATTGATGAAGATGTTGTGGTGATAGAAGCTTCCTCCACTCCCC
AGGTTACTGCCAATGAAGAAATTAATGTTACCTCAACTGACAGTGAAGTGGAGATTGTAACAGTTGGAGAAAGCTATCGGTCTCGTTCAA
CCCTTGGACACTCCAGATCTCATTGGAGCCAGGGTTCCAGTTCTCATGCAAGTCGGCCACAGGAGCCACGGAACCGCAGTAGGATTTCTA
CTGTTATACAGCCCTTGAGGCAGAATGCAGCAGAAGTTGTGGACCTTACCGTTGATGAAGATGAACCTACTGTAGTACCAACCACTTCTG
CAAGAATGGAATCACAAGCTACTAGCGCTTCCATTAACAATTCAAATCCATCTACCTCTGAGCAGGCCTCTGATACTGCTTCAGCTGTCA
CCAGTAGCCAACCTTCCACAGTGTCAGAGACTTCAGCTACTCTTACAAGCAATAGTACCACTGGCACTTCTATAGGAGATGACTCAAGGA
GAACTACATCTAGTGCTGTAACGGAAACTGGCCCTCCTGCAATGCCAAGGTTACCTTCCTGCTGTCCCCAGCACTCACCATGTGGAGGGT
CGTCACAGAACCACCATGCATTAGGACATCCTCATACAAGTTGCTTTCAGCAGCATGGTCACCATTTTCAACATCATCACCACCACCACC
ATACTCCCCACCCAGCTGTCCCAGTTTCTCCTTCCTTTAGTGATCCTGCTTGCCCTGTGGAAAGACCTCCACAAGTACAAGCACCTTGTG
GAGCAAATAGTAGTTCTGGTACCAGCTATCATGAACAGGATGGTGAGGAAGAAGAAAATGAGAAAGATATAGCAGGTTCTGGTGATGGTA
CACAAGAAGTATCTAAACCTCTTCCTTCAGAAGGGAGCCTAGCTGAGGCTGATCACACAGCTCATGAAGAGATGGAAGCTCATACGACTG
TGAAAGAAGCTGAGGATGACAACATCTCGGTCACAATCCAGGCTGAAGATGCCATCACTCTGGATTTTGATGGTGATGACCTCCTAGAAA
CAGGTAAAAATGTGAAAATTACAGATTCTGAAGCAAGTAAGCCAAAAGATGGGCAGGACGCCATTGCACAGAGCCCGGAGAAGGAAAGCA
AGGATTATGAGATGAATGCGAACCATAAAGATGGTAAGAAGGAAGACTGCGTGAAGGGTGACCCTGTCGAGAAGGAAGCCAGAGAAAGTT
CTAAGAAAGCAGAATCTGGAGACAAAGAAAAGGATACTTTGAAGAAAGGGCCCTCGTCTACTGGGGCCTCTGGTCAAGCAAAGAGCTCTT
CAAAGGAATCTAAAGACAGCAAGACATCATCTAAAGATGACAAAGGAAGTACAAGTAGTACTAGTGGTAGCAGTGGAAGCTCAACTAAAA
ATATCTGGGTTAGTGGACTTTCATCTAATACCAAAGCTGCTGATTTGAAGAACCTCTTTGGCAAATATGGAAAGGTTCTGAGTGCAAAAG
TAGTTACAAATGCTCGAAGTCCTGGGGCAAAATGCTATGGCATTGTAACTATGTCTTCAAGCACAGAGGTGTCCAGGTGTATTGCACATC
TTCATCGCACTGAGCTGCATGGACAGCTGATTTCTGTTGAAAAAGTAAAAGGTGATCCCTCTAAGAAAGAAATGAAGAAAGAAAATGATG
AAAAGAGTAGTTCAAGAAGTTCTGGAGATAAAAAAAATACGAGTGATAGAAGTAGCAAGACACAAGCCTCTGTCAAAAAAGAAGAGAAAA
GATCGTCTGAGAAATCTGAAAAAAAAGAAAGCAAGGATACTAAGAAAATAGAAGGTAAAGATGAGAAGAATGATAATGGAGCAAGTGGCC
AAACATCAGAATCGATTAAAAAAAGTGAAGAAAAGAAGCGAATAAGTTCCAAGAGTCCAGGACATATGGTAATACTAGACCAAACTAAAG
GAGATCATTGTAGACCATCAAGAAGAGGAAGATATGAGAAAATTCATGGAAGAAGTAAGGAAAAGGAGAGAGCTAGTCTAGATAAAAAAA
GAGATAAAGACTACAGAAGGAAAGAGATCTTGCCTTTTGAAAAGATGAAGGAACAAAGGTTGAGAGAACATTTAGTTCGTTTTGAAAGGC
TGCGACGAGCAATGGAACTTCGAAGACGAAGAGAGATTGCAGAGAGAGAGCGTCGAGAGCGAGAACGCATTAGAATAATTCGTGAACGGG
AAGAACGGGAACGCTTACAGAGAGAGAGAGAGCGCCTAGAAATTGAAAGGCAAAAACTAGAGAGAGAGAGAATGGAACGCGAACGCTTGG
AAAGGGAACGCATTCGTATTGAACAGGAACGTCGTAAGGAAGCTGAACGGATTGCTCGAGAAAGAGAGGAACTCAGAAGGCAACAACAGC
AGCTTCGTTATGAACAAGAAAAAAGGAATTCCTTGAAACGCCCACGTGATGTAGATCATAGGCGAGATGATCCTTACTGGAGCGAGAATA
AAAAGTTGTCTCTAGATACAGATGCACGATTTGGCCATGGATCCGACTACTCTCGCCAACAGAACAGATTTAATGACTTTGATCACCGAG
AGAGGGGCAGGTTTCCTGAGAGTTCAGCAGTACAGTCTTCATCTTTTGAAAGGCGGGATCGCTTTGTTGGTCAAAGTGAGGGGAAAAAAG
CACGACCTACTGCACGAAGGGAAGATCCAAGCTTCGAAAGATATCCCAAAAATTTCAGTGACTCCAGAAGAAATGAGCCTCCACCACCAA
GAAATGAACTTAGAGAATCAGACAGGCGAGAAGTACGAGGGGAGCGAGACGAAAGGAGAACGGTGATTATTCATGACAGGCCTGATATCA
CTCATCCTAGACATCCTCGAGAGGCAGGGCCCAATCCTTCCAGACCCACCAGCTGGAAAAGTGAAGGAAGCATGTCCACTGACAAACGGG
AAACAAGAGTTGAAAGGCCAGAACGATCTGGGAGAGAAGTATCAGGGCACAGTGTGAGAGGCGCTCCCCCTGGGAATCGTAGCAGCGCTT
CGGGGTACGGGAGCAGAGAGGGAGACAGAGGAGTCATCACAGACCGAGGAGGTGGATCACAGCACTATCCTGAGGAGCGACATGTGGTTG
AACGCCATGGACGGGACACAAGCGGACCAAGGAAAGAGTGGCATGGTCCACCCTCTCAAGGGCCTAGCTATCATGATACGAGGCGAATGG
GTGACGGCCGGGCAGGAGCAGGCATGATAACCCAACATTCAAGTAACGCATCCCCAATTAATAGAATTGTACAAATCAGTGGCAATTCCA
TGCCAAGAGGAAGTGGCTCCGGATTTAAGCCATTTAAGGGTGGACCTCCGCGACGATTCTGAAAATGAGCTCTCTGCCAAGGTTTTAAGA
TAATTTATTGAAATCTCCTGTAAACTTTACTTGACTACTTATGAAGAGGACCTCTGACTTGCTTGAGAGTTCTGTCAGACTTTTCTTTTT
AAAAATTTAACATGATTGCTTTTCTCAATTTTGGAGAAGATGTTTAAATAGTTCTGTTGTAACTTTTAATAGTTTTGTGTATCATTCAAC
TTTTTTTCTTGCAGCACCGAGGCACATTTGAAAAGATGGAATTGAAGTCGTTTTGTTTAACGCTGTGTGAATATAAAGAGTAGTTTGCAG
CTGTGTGGTAGTGGTTTAATTTGCAGCCTTAGCTCTGTGGTGTCTGGCTCTAGAGTTACTTCTTTTTACCAAGCATTTTCAGCCTCCATT
TTGAAGGCTGTCTACACTTAAGAAGTCTTAGCTGTCTAATTTTTAGAGAATAAGATTGTTCATTGCATTTCTGAGTATTATGTAACCTAT
TTTTGCAGAAGGTACTGTTACATTAAGTGCATCTGTGTATCCTGGTTTAAAAAAATGTAATCTTTTTTGAAATAAACCTTCATATTCTGT
ATAGTTGCTAAAGTGTTGAGAACCTTTTTAATTGTAAAATGAGAACCGATTTTCAGTTTAGTGTAGCAGCACACTTGTTCAGGTTTGCAT
GGTATGAAACCAAATAGATTCATGAAACCTTGGCCATGAGGTTTGTTTCACAAGGTTCTTAGACCGAGTTGTGCAGGTAAGTGCACTTTT
AGGTAATCTGCACTGTTTGTTTGATGGATAAATTCCATCTCTGGGAATTGTGTGGGTATTAATGTTTCCATGTTCCCAACTATGTTGAGA
AGTGGAAAAAAACCCAGGTTCTAGATGGGTGAATCAGTTGGGTTTTGTAAATACTTGTATGTGGGGAAGACATTGTTGTCTTTTTGTGAA

>74699_74699_7_RNF111-SLTM_RNF111_chr15_59359282_ENST00000434298_SLTM_chr15_59193486_ENST00000380516_length(amino acids)=1409AA_BP=561
MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLV
VRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR
SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSS
TEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQ
EPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTT
GTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVE
RPPQVQAPCGANSSSGTSYHEQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITL
DFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSST
GASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSS
TEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKD
EKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRL
REHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARE
REELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDR
FVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKS
EGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPPSQG

--------------------------------------------------------------
>74699_74699_8_RNF111-SLTM_RNF111_chr15_59359282_ENST00000557998_SLTM_chr15_59193486_ENST00000380516_length(transcript)=5471nt_BP=1973nt
TGGAGGGGAGAAAGAGGAAGGGCTGCGGCCGCGGAAGGCTGGGGTCGGTGACCGGCCGGTTATCTCTGGCTCGGTGGTGACTTAGGGTCT
GGGTCTCCGCAGACGATTTGTGTTTGGGCAAGGCATTCGTCTACCGACACACCCACAGCCTACAGTGAGGGAGTGTGGGTGAGGGGATTT
CTCTCCCACTTCCGACTCTCCCTAGAGTCTCAGGATGGGGGCTGAGGACCGAGGCGTGGGAGTGCGATTTGACAATGGAGTGATGAAGGC
TTTCCTTAAAGTTTCCCATGTCTCAATGGACTCCTGAATATAACGAGCTCTACACCTTAAAAGTGGATATGAAGAGTGAGATTCCTTCTG
ATGCACCAAAGACACAGGAGAGTCTGAAAGGGATCCTTTTGCATCCAGAGCCCATTGGGGCAGCCAAAAGTTTTCCTGCAGGAGTTGAGA
TGATTAATAGTAAAGTGGGGAATGAATTCTCTCACCTGTGTGATGATTCTCAAAAGCAAGAGAAGGAAATGAATGGTAACCAGCAAGAAC
AAGAAAAAAGTCTCGTTGTGAGGAAAAAACGCAAAAGCCAGCAGGCTGGCCCTTCGTATGTGCAGAATTGTGTTAAAGAAAACCAGGGAA
TATTAGGACTGAGGCAACACCTAGGGACACCAAGTGATGAAGATAATGATTCCTCTTTTAGTGATTGTCTTTCTTCTCCTTCATCTAGTC
TGCATTTTGGAGATTCTGATACTGTGACTTCAGATGAGGATAAAGAAGTCTCTGTAAGACATTCCCAGACCATTTTGAATGCTAAAAGTA
GAAGCCATAGTGCACGGTCTCATAAGTGGCCTCGGACTGAGACAGAATCTGTATCGGGATTGTTAATGAAAAGACCCTGTTTACATGGCA
GTTCGTTACGGAGACTTCCATGCAGAAAGAGATTTGTAAAAAATAATTCCTCACAGAGGACACAGAAACAAAAAGAGAGGATATTAATGC
AGAGGAAGAAACGAGAAGTGTTAGCTCGAAGAAAATATGCCTTGCTACCTAGTTCTAGTAGTTCCAGTGAGAATGACCTCAGCAGTGAAT
CCTCTTCTAGCTCATCAACTGAAGGAGAAGAAGATTTGTTTGTTTCTGCCAGTGAAAACCACCAAAACAATCCAGCTGTTCCCTCAGGAA
GTATTGATGAAGATGTTGTGGTGATAGAAGCTTCCTCCACTCCCCAGGTTACTGCCAATGAAGAAATTAATGTTACCTCAACTGACAGTG
AAGTGGAGATTGTAACAGTTGGAGAAAGCTATCGGTCTCGTTCAACCCTTGGACACTCCAGATCTCATTGGAGCCAGGGTTCCAGTTCTC
ATGCAAGTCGGCCACAGGAGCCACGGAACCGCAGTAGGATTTCTACTGTTATACAGCCCTTGAGGCAGAATGCAGCAGAAGTTGTGGACC
TTACCGTTGATGAAGATGAACCTACTGTAGTACCAACCACTTCTGCAAGAATGGAATCACAAGCTACTAGCGCTTCCATTAACAATTCAA
ATCCATCTACCTCTGAGCAGGCCTCTGATACTGCTTCAGCTGTCACCAGTAGCCAACCTTCCACAGTGTCAGAGACTTCAGCTACTCTTA
CAAGCAATAGTACCACTGGCACTTCTATAGGAGATGACTCAAGGAGAACTACATCTAGTGCTGTAACGGAAACTGGCCCTCCTGCAATGC
CAAGGTTACCTTCCTGCTGTCCCCAGCACTCACCATGTGGAGGGTCGTCACAGAACCACCATGCATTAGGACATCCTCATACAAGTTGCT
TTCAGCAGCATGGTCACCATTTTCAACATCATCACCACCACCACCATACTCCCCACCCAGCTGTCCCAGTTTCTCCTTCCTTTAGTGATC
CTGCTTGCCCTGTGGAAAGACCTCCACAAGTACAAGCACCTTGTGGAGCAAATAGTAGTTCTGGTACCAGCTATCATGAACAGGATGGTG
AGGAAGAAGAAAATGAGAAAGATATAGCAGGTTCTGGTGATGGTACACAAGAAGTATCTAAACCTCTTCCTTCAGAAGGGAGCCTAGCTG
AGGCTGATCACACAGCTCATGAAGAGATGGAAGCTCATACGACTGTGAAAGAAGCTGAGGATGACAACATCTCGGTCACAATCCAGGCTG
AAGATGCCATCACTCTGGATTTTGATGGTGATGACCTCCTAGAAACAGGTAAAAATGTGAAAATTACAGATTCTGAAGCAAGTAAGCCAA
AAGATGGGCAGGACGCCATTGCACAGAGCCCGGAGAAGGAAAGCAAGGATTATGAGATGAATGCGAACCATAAAGATGGTAAGAAGGAAG
ACTGCGTGAAGGGTGACCCTGTCGAGAAGGAAGCCAGAGAAAGTTCTAAGAAAGCAGAATCTGGAGACAAAGAAAAGGATACTTTGAAGA
AAGGGCCCTCGTCTACTGGGGCCTCTGGTCAAGCAAAGAGCTCTTCAAAGGAATCTAAAGACAGCAAGACATCATCTAAAGATGACAAAG
GAAGTACAAGTAGTACTAGTGGTAGCAGTGGAAGCTCAACTAAAAATATCTGGGTTAGTGGACTTTCATCTAATACCAAAGCTGCTGATT
TGAAGAACCTCTTTGGCAAATATGGAAAGGTTCTGAGTGCAAAAGTAGTTACAAATGCTCGAAGTCCTGGGGCAAAATGCTATGGCATTG
TAACTATGTCTTCAAGCACAGAGGTGTCCAGGTGTATTGCACATCTTCATCGCACTGAGCTGCATGGACAGCTGATTTCTGTTGAAAAAG
TAAAAGGTGATCCCTCTAAGAAAGAAATGAAGAAAGAAAATGATGAAAAGAGTAGTTCAAGAAGTTCTGGAGATAAAAAAAATACGAGTG
ATAGAAGTAGCAAGACACAAGCCTCTGTCAAAAAAGAAGAGAAAAGATCGTCTGAGAAATCTGAAAAAAAAGAAAGCAAGGATACTAAGA
AAATAGAAGGTAAAGATGAGAAGAATGATAATGGAGCAAGTGGCCAAACATCAGAATCGATTAAAAAAAGTGAAGAAAAGAAGCGAATAA
GTTCCAAGAGTCCAGGACATATGGTAATACTAGACCAAACTAAAGGAGATCATTGTAGACCATCAAGAAGAGGAAGATATGAGAAAATTC
ATGGAAGAAGTAAGGAAAAGGAGAGAGCTAGTCTAGATAAAAAAAGAGATAAAGACTACAGAAGGAAAGAGATCTTGCCTTTTGAAAAGA
TGAAGGAACAAAGGTTGAGAGAACATTTAGTTCGTTTTGAAAGGCTGCGACGAGCAATGGAACTTCGAAGACGAAGAGAGATTGCAGAGA
GAGAGCGTCGAGAGCGAGAACGCATTAGAATAATTCGTGAACGGGAAGAACGGGAACGCTTACAGAGAGAGAGAGAGCGCCTAGAAATTG
AAAGGCAAAAACTAGAGAGAGAGAGAATGGAACGCGAACGCTTGGAAAGGGAACGCATTCGTATTGAACAGGAACGTCGTAAGGAAGCTG
AACGGATTGCTCGAGAAAGAGAGGAACTCAGAAGGCAACAACAGCAGCTTCGTTATGAACAAGAAAAAAGGAATTCCTTGAAACGCCCAC
GTGATGTAGATCATAGGCGAGATGATCCTTACTGGAGCGAGAATAAAAAGTTGTCTCTAGATACAGATGCACGATTTGGCCATGGATCCG
ACTACTCTCGCCAACAGAACAGATTTAATGACTTTGATCACCGAGAGAGGGGCAGGTTTCCTGAGAGTTCAGCAGTACAGTCTTCATCTT
TTGAAAGGCGGGATCGCTTTGTTGGTCAAAGTGAGGGGAAAAAAGCACGACCTACTGCACGAAGGGAAGATCCAAGCTTCGAAAGATATC
CCAAAAATTTCAGTGACTCCAGAAGAAATGAGCCTCCACCACCAAGAAATGAACTTAGAGAATCAGACAGGCGAGAAGTACGAGGGGAGC
GAGACGAAAGGAGAACGGTGATTATTCATGACAGGCCTGATATCACTCATCCTAGACATCCTCGAGAGGCAGGGCCCAATCCTTCCAGAC
CCACCAGCTGGAAAAGTGAAGGAAGCATGTCCACTGACAAACGGGAAACAAGAGTTGAAAGGCCAGAACGATCTGGGAGAGAAGTATCAG
GGCACAGTGTGAGAGGCGCTCCCCCTGGGAATCGTAGCAGCGCTTCGGGGTACGGGAGCAGAGAGGGAGACAGAGGAGTCATCACAGACC
GAGGAGGTGGATCACAGCACTATCCTGAGGAGCGACATGTGGTTGAACGCCATGGACGGGACACAAGCGGACCAAGGAAAGAGTGGCATG
GTCCACCCTCTCAAGGGCCTAGCTATCATGATACGAGGCGAATGGGTGACGGCCGGGCAGGAGCAGGCATGATAACCCAACATTCAAGTA
ACGCATCCCCAATTAATAGAATTGTACAAATCAGTGGCAATTCCATGCCAAGAGGAAGTGGCTCCGGATTTAAGCCATTTAAGGGTGGAC
CTCCGCGACGATTCTGAAAATGAGCTCTCTGCCAAGGTTTTAAGATAATTTATTGAAATCTCCTGTAAACTTTACTTGACTACTTATGAA
GAGGACCTCTGACTTGCTTGAGAGTTCTGTCAGACTTTTCTTTTTAAAAATTTAACATGATTGCTTTTCTCAATTTTGGAGAAGATGTTT
AAATAGTTCTGTTGTAACTTTTAATAGTTTTGTGTATCATTCAACTTTTTTTCTTGCAGCACCGAGGCACATTTGAAAAGATGGAATTGA
AGTCGTTTTGTTTAACGCTGTGTGAATATAAAGAGTAGTTTGCAGCTGTGTGGTAGTGGTTTAATTTGCAGCCTTAGCTCTGTGGTGTCT
GGCTCTAGAGTTACTTCTTTTTACCAAGCATTTTCAGCCTCCATTTTGAAGGCTGTCTACACTTAAGAAGTCTTAGCTGTCTAATTTTTA
GAGAATAAGATTGTTCATTGCATTTCTGAGTATTATGTAACCTATTTTTGCAGAAGGTACTGTTACATTAAGTGCATCTGTGTATCCTGG
TTTAAAAAAATGTAATCTTTTTTGAAATAAACCTTCATATTCTGTATAGTTGCTAAAGTGTTGAGAACCTTTTTAATTGTAAAATGAGAA
CCGATTTTCAGTTTAGTGTAGCAGCACACTTGTTCAGGTTTGCATGGTATGAAACCAAATAGATTCATGAAACCTTGGCCATGAGGTTTG
TTTCACAAGGTTCTTAGACCGAGTTGTGCAGGTAAGTGCACTTTTAGGTAATCTGCACTGTTTGTTTGATGGATAAATTCCATCTCTGGG
AATTGTGTGGGTATTAATGTTTCCATGTTCCCAACTATGTTGAGAAGTGGAAAAAAACCCAGGTTCTAGATGGGTGAATCAGTTGGGTTT

>74699_74699_8_RNF111-SLTM_RNF111_chr15_59359282_ENST00000557998_SLTM_chr15_59193486_ENST00000380516_length(amino acids)=1409AA_BP=561
MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLV
VRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR
SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSS
TEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQ
EPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTT
GTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVE
RPPQVQAPCGANSSSGTSYHEQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITL
DFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSST
GASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSS
TEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKD
EKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRL
REHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARE
REELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDR
FVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKS
EGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPPSQG

--------------------------------------------------------------
>74699_74699_9_RNF111-SLTM_RNF111_chr15_59359282_ENST00000559209_SLTM_chr15_59193486_ENST00000380516_length(transcript)=5320nt_BP=1822nt
CTGAGGCGCAGATCGCTGGCTCTCGACGCATTACTCTTTACGCCTTACATTTCTGTCTTCCTTCCTGGGTCAGTGATTCCCGGACCCTGG
AAGAGAAGAGGGTGGCTAATGATTAAGGCTTTCCTTAAAGTTTCCCATGTCTCAATGGACTCCTGAATATAACGAGCTCTACACCTTAAA
AGTGGATATGAAGAGTGAGATTCCTTCTGATGCACCAAAGACACAGGAGAGTCTGAAAGGGATCCTTTTGCATCCAGAGCCCATTGGGGC
AGCCAAAAGTTTTCCTGCAGGAGTTGAGATGATTAATAGTAAAGTGGGGAATGAATTCTCTCACCTGTGTGATGATTCTCAAAAGCAAGA
GAAGGAAATGAATGGTAACCAGCAAGAACAAGAAAAAAGTCTCGTTGTGAGGAAAAAACGCAAAAGCCAGCAGGCTGGCCCTTCGTATGT
GCAGAATTGTGTTAAAGAAAACCAGGGAATATTAGGACTGAGGCAACACCTAGGGACACCAAGTGATGAAGATAATGATTCCTCTTTTAG
TGATTGTCTTTCTTCTCCTTCATCTAGTCTGCATTTTGGAGATTCTGATACTGTGACTTCAGATGAGGATAAAGAAGTCTCTGTAAGACA
TTCCCAGACCATTTTGAATGCTAAAAGTAGAAGCCATAGTGCACGGTCTCATAAGTGGCCTCGGACTGAGACAGAATCTGTATCGGGATT
GTTAATGAAAAGACCCTGTTTACATGGCAGTTCGTTACGGAGACTTCCATGCAGAAAGAGATTTGTAAAAAATAATTCCTCACAGAGGAC
ACAGAAACAAAAAGAGAGGATATTAATGCAGAGGAAGAAACGAGAAGTGTTAGCTCGAAGAAAATATGCCTTGCTACCTAGTTCTAGTAG
TTCCAGTGAGAATGACCTCAGCAGTGAATCCTCTTCTAGCTCATCAACTGAAGGAGAAGAAGATTTGTTTGTTTCTGCCAGTGAAAACCA
CCAAAACAATCCAGCTGTTCCCTCAGGAAGTATTGATGAAGATGTTGTGGTGATAGAAGCTTCCTCCACTCCCCAGGTTACTGCCAATGA
AGAAATTAATGTTACCTCAACTGACAGTGAAGTGGAGATTGTAACAGTTGGAGAAAGCTATCGGTCTCGTTCAACCCTTGGACACTCCAG
ATCTCATTGGAGCCAGGGTTCCAGTTCTCATGCAAGTCGGCCACAGGAGCCACGGAACCGCAGTAGGATTTCTACTGTTATACAGCCCTT
GAGGCAGAATGCAGCAGAAGTTGTGGACCTTACCGTTGATGAAGATGAACCTACTGTAGTACCAACCACTTCTGCAAGAATGGAATCACA
AGCTACTAGCGCTTCCATTAACAATTCAAATCCATCTACCTCTGAGCAGGCCTCTGATACTGCTTCAGCTGTCACCAGTAGCCAACCTTC
CACAGTGTCAGAGACTTCAGCTACTCTTACAAGCAATAGTACCACTGGCACTTCTATAGGAGATGACTCAAGGAGAACTACATCTAGTGC
TGTAACGGAAACTGGCCCTCCTGCAATGCCAAGGTTACCTTCCTGCTGTCCCCAGCACTCACCATGTGGAGGGTCGTCACAGAACCACCA
TGCATTAGGACATCCTCATACAAGTTGCTTTCAGCAGCATGGTCACCATTTTCAACATCATCACCACCACCACCATACTCCCCACCCAGC
TGTCCCAGTTTCTCCTTCCTTTAGTGATCCTGCTTGCCCTGTGGAAAGACCTCCACAAGTACAAGCACCTTGTGGAGCAAATAGTAGTTC
TGGTACCAGCTATCATGAACAGGATGGTGAGGAAGAAGAAAATGAGAAAGATATAGCAGGTTCTGGTGATGGTACACAAGAAGTATCTAA
ACCTCTTCCTTCAGAAGGGAGCCTAGCTGAGGCTGATCACACAGCTCATGAAGAGATGGAAGCTCATACGACTGTGAAAGAAGCTGAGGA
TGACAACATCTCGGTCACAATCCAGGCTGAAGATGCCATCACTCTGGATTTTGATGGTGATGACCTCCTAGAAACAGGTAAAAATGTGAA
AATTACAGATTCTGAAGCAAGTAAGCCAAAAGATGGGCAGGACGCCATTGCACAGAGCCCGGAGAAGGAAAGCAAGGATTATGAGATGAA
TGCGAACCATAAAGATGGTAAGAAGGAAGACTGCGTGAAGGGTGACCCTGTCGAGAAGGAAGCCAGAGAAAGTTCTAAGAAAGCAGAATC
TGGAGACAAAGAAAAGGATACTTTGAAGAAAGGGCCCTCGTCTACTGGGGCCTCTGGTCAAGCAAAGAGCTCTTCAAAGGAATCTAAAGA
CAGCAAGACATCATCTAAAGATGACAAAGGAAGTACAAGTAGTACTAGTGGTAGCAGTGGAAGCTCAACTAAAAATATCTGGGTTAGTGG
ACTTTCATCTAATACCAAAGCTGCTGATTTGAAGAACCTCTTTGGCAAATATGGAAAGGTTCTGAGTGCAAAAGTAGTTACAAATGCTCG
AAGTCCTGGGGCAAAATGCTATGGCATTGTAACTATGTCTTCAAGCACAGAGGTGTCCAGGTGTATTGCACATCTTCATCGCACTGAGCT
GCATGGACAGCTGATTTCTGTTGAAAAAGTAAAAGGTGATCCCTCTAAGAAAGAAATGAAGAAAGAAAATGATGAAAAGAGTAGTTCAAG
AAGTTCTGGAGATAAAAAAAATACGAGTGATAGAAGTAGCAAGACACAAGCCTCTGTCAAAAAAGAAGAGAAAAGATCGTCTGAGAAATC
TGAAAAAAAAGAAAGCAAGGATACTAAGAAAATAGAAGGTAAAGATGAGAAGAATGATAATGGAGCAAGTGGCCAAACATCAGAATCGAT
TAAAAAAAGTGAAGAAAAGAAGCGAATAAGTTCCAAGAGTCCAGGACATATGGTAATACTAGACCAAACTAAAGGAGATCATTGTAGACC
ATCAAGAAGAGGAAGATATGAGAAAATTCATGGAAGAAGTAAGGAAAAGGAGAGAGCTAGTCTAGATAAAAAAAGAGATAAAGACTACAG
AAGGAAAGAGATCTTGCCTTTTGAAAAGATGAAGGAACAAAGGTTGAGAGAACATTTAGTTCGTTTTGAAAGGCTGCGACGAGCAATGGA
ACTTCGAAGACGAAGAGAGATTGCAGAGAGAGAGCGTCGAGAGCGAGAACGCATTAGAATAATTCGTGAACGGGAAGAACGGGAACGCTT
ACAGAGAGAGAGAGAGCGCCTAGAAATTGAAAGGCAAAAACTAGAGAGAGAGAGAATGGAACGCGAACGCTTGGAAAGGGAACGCATTCG
TATTGAACAGGAACGTCGTAAGGAAGCTGAACGGATTGCTCGAGAAAGAGAGGAACTCAGAAGGCAACAACAGCAGCTTCGTTATGAACA
AGAAAAAAGGAATTCCTTGAAACGCCCACGTGATGTAGATCATAGGCGAGATGATCCTTACTGGAGCGAGAATAAAAAGTTGTCTCTAGA
TACAGATGCACGATTTGGCCATGGATCCGACTACTCTCGCCAACAGAACAGATTTAATGACTTTGATCACCGAGAGAGGGGCAGGTTTCC
TGAGAGTTCAGCAGTACAGTCTTCATCTTTTGAAAGGCGGGATCGCTTTGTTGGTCAAAGTGAGGGGAAAAAAGCACGACCTACTGCACG
AAGGGAAGATCCAAGCTTCGAAAGATATCCCAAAAATTTCAGTGACTCCAGAAGAAATGAGCCTCCACCACCAAGAAATGAACTTAGAGA
ATCAGACAGGCGAGAAGTACGAGGGGAGCGAGACGAAAGGAGAACGGTGATTATTCATGACAGGCCTGATATCACTCATCCTAGACATCC
TCGAGAGGCAGGGCCCAATCCTTCCAGACCCACCAGCTGGAAAAGTGAAGGAAGCATGTCCACTGACAAACGGGAAACAAGAGTTGAAAG
GCCAGAACGATCTGGGAGAGAAGTATCAGGGCACAGTGTGAGAGGCGCTCCCCCTGGGAATCGTAGCAGCGCTTCGGGGTACGGGAGCAG
AGAGGGAGACAGAGGAGTCATCACAGACCGAGGAGGTGGATCACAGCACTATCCTGAGGAGCGACATGTGGTTGAACGCCATGGACGGGA
CACAAGCGGACCAAGGAAAGAGTGGCATGGTCCACCCTCTCAAGGGCCTAGCTATCATGATACGAGGCGAATGGGTGACGGCCGGGCAGG
AGCAGGCATGATAACCCAACATTCAAGTAACGCATCCCCAATTAATAGAATTGTACAAATCAGTGGCAATTCCATGCCAAGAGGAAGTGG
CTCCGGATTTAAGCCATTTAAGGGTGGACCTCCGCGACGATTCTGAAAATGAGCTCTCTGCCAAGGTTTTAAGATAATTTATTGAAATCT
CCTGTAAACTTTACTTGACTACTTATGAAGAGGACCTCTGACTTGCTTGAGAGTTCTGTCAGACTTTTCTTTTTAAAAATTTAACATGAT
TGCTTTTCTCAATTTTGGAGAAGATGTTTAAATAGTTCTGTTGTAACTTTTAATAGTTTTGTGTATCATTCAACTTTTTTTCTTGCAGCA
CCGAGGCACATTTGAAAAGATGGAATTGAAGTCGTTTTGTTTAACGCTGTGTGAATATAAAGAGTAGTTTGCAGCTGTGTGGTAGTGGTT
TAATTTGCAGCCTTAGCTCTGTGGTGTCTGGCTCTAGAGTTACTTCTTTTTACCAAGCATTTTCAGCCTCCATTTTGAAGGCTGTCTACA
CTTAAGAAGTCTTAGCTGTCTAATTTTTAGAGAATAAGATTGTTCATTGCATTTCTGAGTATTATGTAACCTATTTTTGCAGAAGGTACT
GTTACATTAAGTGCATCTGTGTATCCTGGTTTAAAAAAATGTAATCTTTTTTGAAATAAACCTTCATATTCTGTATAGTTGCTAAAGTGT
TGAGAACCTTTTTAATTGTAAAATGAGAACCGATTTTCAGTTTAGTGTAGCAGCACACTTGTTCAGGTTTGCATGGTATGAAACCAAATA
GATTCATGAAACCTTGGCCATGAGGTTTGTTTCACAAGGTTCTTAGACCGAGTTGTGCAGGTAAGTGCACTTTTAGGTAATCTGCACTGT
TTGTTTGATGGATAAATTCCATCTCTGGGAATTGTGTGGGTATTAATGTTTCCATGTTCCCAACTATGTTGAGAAGTGGAAAAAAACCCA
GGTTCTAGATGGGTGAATCAGTTGGGTTTTGTAAATACTTGTATGTGGGGAAGACATTGTTGTCTTTTTGTGAAAATAAAAATCCACACC

>74699_74699_9_RNF111-SLTM_RNF111_chr15_59359282_ENST00000559209_SLTM_chr15_59193486_ENST00000380516_length(amino acids)=1409AA_BP=561
MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLV
VRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR
SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSS
TEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQ
EPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTT
GTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVE
RPPQVQAPCGANSSSGTSYHEQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITL
DFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSST
GASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSS
TEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKD
EKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRL
REHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARE
REELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDR
FVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKS
EGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPPSQG

--------------------------------------------------------------
>74699_74699_10_RNF111-SLTM_RNF111_chr15_59359282_ENST00000561186_SLTM_chr15_59193486_ENST00000380516_length(transcript)=5184nt_BP=1686nt
ATGTCTCAATGGACTCCTGAATATAACGAGCTCTACACCTTAAAAGTGGATATGAAGAGTGAGATTCCTTCTGATGCACCAAAGACACAG
GAGAGTCTGAAAGGGATCCTTTTGCATCCAGAGCCCATTGGGGCAGCCAAAAGTTTTCCTGCAGGAGTTGAGATGATTAATAGTAAAGTG
GGGAATGAATTCTCTCACCTGTGTGATGATTCTCAAAAGCAAGAGAAGGAAATGAATGGTAACCAGCAAGAACAAGAAAAAAGTCTCGTT
GTGAGGAAAAAACGCAAAAGCCAGCAGGCTGGCCCTTCGTATGTGCAGAATTGTGTTAAAGAAAACCAGGGAATATTAGGACTGAGGCAA
CACCTAGGGACACCAAGTGATGAAGATAATGATTCCTCTTTTAGTGATTGTCTTTCTTCTCCTTCATCTAGTCTGCATTTTGGAGATTCT
GATACTGTGACTTCAGATGAGGATAAAGAAGTCTCTGTAAGACATTCCCAGACCATTTTGAATGCTAAAAGTAGAAGCCATAGTGCACGG
TCTCATAAGTGGCCTCGGACTGAGACAGAATCTGTATCGGGATTGTTAATGAAAAGACCCTGTTTACATGGCAGTTCGTTACGGAGACTT
CCATGCAGAAAGAGATTTGTAAAAAATAATTCCTCACAGAGGACACAGAAACAAAAAGAGAGGATATTAATGCAGAGGAAGAAACGAGAA
GTGTTAGCTCGAAGAAAATATGCCTTGCTACCTAGTTCTAGTAGTTCCAGTGAGAATGACCTCAGCAGTGAATCCTCTTCTAGCTCATCA
ACTGAAGGAGAAGAAGATTTGTTTGTTTCTGCCAGTGAAAACCACCAAAACAATCCAGCTGTTCCCTCAGGAAGTATTGATGAAGATGTT
GTGGTGATAGAAGCTTCCTCCACTCCCCAGGTTACTGCCAATGAAGAAATTAATGTTACCTCAACTGACAGTGAAGTGGAGATTGTAACA
GTTGGAGAAAGCTATCGGTCTCGTTCAACCCTTGGACACTCCAGATCTCATTGGAGCCAGGGTTCCAGTTCTCATGCAAGTCGGCCACAG
GAGCCACGGAACCGCAGTAGGATTTCTACTGTTATACAGCCCTTGAGGCAGAATGCAGCAGAAGTTGTGGACCTTACCGTTGATGAAGAT
GAACCTACTGTAGTACCAACCACTTCTGCAAGAATGGAATCACAAGCTACTAGCGCTTCCATTAACAATTCAAATCCATCTACCTCTGAG
CAGGCCTCTGATACTGCTTCAGCTGTCACCAGTAGCCAACCTTCCACAGTGTCAGAGACTTCAGCTACTCTTACAAGCAATAGTACCACT
GGCACTTCTATAGGAGATGACTCAAGGAGAACTACATCTAGTGCTGTAACGGAAACTGGCCCTCCTGCAATGCCAAGGTTACCTTCCTGC
TGTCCCCAGCACTCACCATGTGGAGGGTCGTCACAGAACCACCATGCATTAGGACATCCTCATACAAGTTGCTTTCAGCAGCATGGTCAC
CATTTTCAACATCATCACCACCACCACCATACTCCCCACCCAGCTGTCCCAGTTTCTCCTTCCTTTAGTGATCCTGCTTGCCCTGTGGAA
AGACCTCCACAAGTACAAGCACCTTGTGGAGCAAATAGTAGTTCTGGTACCAGCTATCATGAACAGGATGGTGAGGAAGAAGAAAATGAG
AAAGATATAGCAGGTTCTGGTGATGGTACACAAGAAGTATCTAAACCTCTTCCTTCAGAAGGGAGCCTAGCTGAGGCTGATCACACAGCT
CATGAAGAGATGGAAGCTCATACGACTGTGAAAGAAGCTGAGGATGACAACATCTCGGTCACAATCCAGGCTGAAGATGCCATCACTCTG
GATTTTGATGGTGATGACCTCCTAGAAACAGGTAAAAATGTGAAAATTACAGATTCTGAAGCAAGTAAGCCAAAAGATGGGCAGGACGCC
ATTGCACAGAGCCCGGAGAAGGAAAGCAAGGATTATGAGATGAATGCGAACCATAAAGATGGTAAGAAGGAAGACTGCGTGAAGGGTGAC
CCTGTCGAGAAGGAAGCCAGAGAAAGTTCTAAGAAAGCAGAATCTGGAGACAAAGAAAAGGATACTTTGAAGAAAGGGCCCTCGTCTACT
GGGGCCTCTGGTCAAGCAAAGAGCTCTTCAAAGGAATCTAAAGACAGCAAGACATCATCTAAAGATGACAAAGGAAGTACAAGTAGTACT
AGTGGTAGCAGTGGAAGCTCAACTAAAAATATCTGGGTTAGTGGACTTTCATCTAATACCAAAGCTGCTGATTTGAAGAACCTCTTTGGC
AAATATGGAAAGGTTCTGAGTGCAAAAGTAGTTACAAATGCTCGAAGTCCTGGGGCAAAATGCTATGGCATTGTAACTATGTCTTCAAGC
ACAGAGGTGTCCAGGTGTATTGCACATCTTCATCGCACTGAGCTGCATGGACAGCTGATTTCTGTTGAAAAAGTAAAAGGTGATCCCTCT
AAGAAAGAAATGAAGAAAGAAAATGATGAAAAGAGTAGTTCAAGAAGTTCTGGAGATAAAAAAAATACGAGTGATAGAAGTAGCAAGACA
CAAGCCTCTGTCAAAAAAGAAGAGAAAAGATCGTCTGAGAAATCTGAAAAAAAAGAAAGCAAGGATACTAAGAAAATAGAAGGTAAAGAT
GAGAAGAATGATAATGGAGCAAGTGGCCAAACATCAGAATCGATTAAAAAAAGTGAAGAAAAGAAGCGAATAAGTTCCAAGAGTCCAGGA
CATATGGTAATACTAGACCAAACTAAAGGAGATCATTGTAGACCATCAAGAAGAGGAAGATATGAGAAAATTCATGGAAGAAGTAAGGAA
AAGGAGAGAGCTAGTCTAGATAAAAAAAGAGATAAAGACTACAGAAGGAAAGAGATCTTGCCTTTTGAAAAGATGAAGGAACAAAGGTTG
AGAGAACATTTAGTTCGTTTTGAAAGGCTGCGACGAGCAATGGAACTTCGAAGACGAAGAGAGATTGCAGAGAGAGAGCGTCGAGAGCGA
GAACGCATTAGAATAATTCGTGAACGGGAAGAACGGGAACGCTTACAGAGAGAGAGAGAGCGCCTAGAAATTGAAAGGCAAAAACTAGAG
AGAGAGAGAATGGAACGCGAACGCTTGGAAAGGGAACGCATTCGTATTGAACAGGAACGTCGTAAGGAAGCTGAACGGATTGCTCGAGAA
AGAGAGGAACTCAGAAGGCAACAACAGCAGCTTCGTTATGAACAAGAAAAAAGGAATTCCTTGAAACGCCCACGTGATGTAGATCATAGG
CGAGATGATCCTTACTGGAGCGAGAATAAAAAGTTGTCTCTAGATACAGATGCACGATTTGGCCATGGATCCGACTACTCTCGCCAACAG
AACAGATTTAATGACTTTGATCACCGAGAGAGGGGCAGGTTTCCTGAGAGTTCAGCAGTACAGTCTTCATCTTTTGAAAGGCGGGATCGC
TTTGTTGGTCAAAGTGAGGGGAAAAAAGCACGACCTACTGCACGAAGGGAAGATCCAAGCTTCGAAAGATATCCCAAAAATTTCAGTGAC
TCCAGAAGAAATGAGCCTCCACCACCAAGAAATGAACTTAGAGAATCAGACAGGCGAGAAGTACGAGGGGAGCGAGACGAAAGGAGAACG
GTGATTATTCATGACAGGCCTGATATCACTCATCCTAGACATCCTCGAGAGGCAGGGCCCAATCCTTCCAGACCCACCAGCTGGAAAAGT
GAAGGAAGCATGTCCACTGACAAACGGGAAACAAGAGTTGAAAGGCCAGAACGATCTGGGAGAGAAGTATCAGGGCACAGTGTGAGAGGC
GCTCCCCCTGGGAATCGTAGCAGCGCTTCGGGGTACGGGAGCAGAGAGGGAGACAGAGGAGTCATCACAGACCGAGGAGGTGGATCACAG
CACTATCCTGAGGAGCGACATGTGGTTGAACGCCATGGACGGGACACAAGCGGACCAAGGAAAGAGTGGCATGGTCCACCCTCTCAAGGG
CCTAGCTATCATGATACGAGGCGAATGGGTGACGGCCGGGCAGGAGCAGGCATGATAACCCAACATTCAAGTAACGCATCCCCAATTAAT
AGAATTGTACAAATCAGTGGCAATTCCATGCCAAGAGGAAGTGGCTCCGGATTTAAGCCATTTAAGGGTGGACCTCCGCGACGATTCTGA
AAATGAGCTCTCTGCCAAGGTTTTAAGATAATTTATTGAAATCTCCTGTAAACTTTACTTGACTACTTATGAAGAGGACCTCTGACTTGC
TTGAGAGTTCTGTCAGACTTTTCTTTTTAAAAATTTAACATGATTGCTTTTCTCAATTTTGGAGAAGATGTTTAAATAGTTCTGTTGTAA
CTTTTAATAGTTTTGTGTATCATTCAACTTTTTTTCTTGCAGCACCGAGGCACATTTGAAAAGATGGAATTGAAGTCGTTTTGTTTAACG
CTGTGTGAATATAAAGAGTAGTTTGCAGCTGTGTGGTAGTGGTTTAATTTGCAGCCTTAGCTCTGTGGTGTCTGGCTCTAGAGTTACTTC
TTTTTACCAAGCATTTTCAGCCTCCATTTTGAAGGCTGTCTACACTTAAGAAGTCTTAGCTGTCTAATTTTTAGAGAATAAGATTGTTCA
TTGCATTTCTGAGTATTATGTAACCTATTTTTGCAGAAGGTACTGTTACATTAAGTGCATCTGTGTATCCTGGTTTAAAAAAATGTAATC
TTTTTTGAAATAAACCTTCATATTCTGTATAGTTGCTAAAGTGTTGAGAACCTTTTTAATTGTAAAATGAGAACCGATTTTCAGTTTAGT
GTAGCAGCACACTTGTTCAGGTTTGCATGGTATGAAACCAAATAGATTCATGAAACCTTGGCCATGAGGTTTGTTTCACAAGGTTCTTAG
ACCGAGTTGTGCAGGTAAGTGCACTTTTAGGTAATCTGCACTGTTTGTTTGATGGATAAATTCCATCTCTGGGAATTGTGTGGGTATTAA
TGTTTCCATGTTCCCAACTATGTTGAGAAGTGGAAAAAAACCCAGGTTCTAGATGGGTGAATCAGTTGGGTTTTGTAAATACTTGTATGT

>74699_74699_10_RNF111-SLTM_RNF111_chr15_59359282_ENST00000561186_SLTM_chr15_59193486_ENST00000380516_length(amino acids)=1409AA_BP=561
MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLV
VRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSAR
SHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSS
TEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQ
EPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTT
GTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVE
RPPQVQAPCGANSSSGTSYHEQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITL
DFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSST
GASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSS
TEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKD
EKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRL
REHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARE
REELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDR
FVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKS
EGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPPSQG

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Fusion Gene PPI Analysis for RNF111-SLTM


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneRNF111chr15:59359282chr15:59193486ENST00000348370+614241_404562.0987.0AXIN1
HgeneRNF111chr15:59359282chr15:59193486ENST00000434298+614241_404562.01004.0AXIN1
HgeneRNF111chr15:59359282chr15:59193486ENST00000557998+614241_404562.0995.0AXIN1
HgeneRNF111chr15:59359282chr15:59193486ENST00000559209+614241_404562.0996.0AXIN1
HgeneRNF111chr15:59359282chr15:59193486ENST00000561186+513241_404562.01004.0AXIN1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneRNF111chr15:59323901chr15:59209198ENST00000348370-214241_404293.3333333333333987.0AXIN1
HgeneRNF111chr15:59323901chr15:59209198ENST00000434298-214241_404293.33333333333331004.0AXIN1
HgeneRNF111chr15:59323901chr15:59209198ENST00000557998-214241_404293.3333333333333995.0AXIN1
HgeneRNF111chr15:59323901chr15:59209198ENST00000559209-214241_404293.3333333333333996.0AXIN1
HgeneRNF111chr15:59323901chr15:59209198ENST00000561186-113241_404293.33333333333331004.0AXIN1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RNF111-SLTM


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RNF111-SLTM


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource