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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RNF121-C6orf132 (FusionGDB2 ID:74726)

Fusion Gene Summary for RNF121-C6orf132

check button Fusion gene summary
Fusion gene informationFusion gene name: RNF121-C6orf132
Fusion gene ID: 74726
HgeneTgene
Gene symbol

RNF121

C6orf132

Gene ID

55298

647024

Gene namering finger protein 121chromosome 6 open reading frame 132
Synonyms-bA7K24.2
Cytomap

11q13.4

6p21.1

Type of geneprotein-codingprotein-coding
DescriptionRING finger protein 121uncharacterized protein C6orf132
Modification date2020031320200313
UniProtAcc.

Q5T0Z8

Ensembl transtripts involved in fusion geneENST00000490867, ENST00000361756, 
ENST00000393713, ENST00000530137, 
ENST00000533380, ENST00000545854, 
ENST00000341865, ENST00000356542, 
Fusion gene scores* DoF score22 X 8 X 11=19368 X 7 X 5=280
# samples 2712
** MAII scorelog2(27/1936*10)=-2.84204764022376
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/280*10)=-1.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RNF121 [Title/Abstract] AND C6orf132 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRNF121(71671937)-C6orf132(42078029), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across RNF121 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across C6orf132 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-IN-8663RNF121chr11

71671937

+C6orf132chr6

42078029

-


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Fusion Gene ORF analysis for RNF121-C6orf132

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000490867ENST00000341865RNF121chr11

71671937

+C6orf132chr6

42078029

-
3UTR-intronENST00000490867ENST00000356542RNF121chr11

71671937

+C6orf132chr6

42078029

-
5CDS-intronENST00000361756ENST00000356542RNF121chr11

71671937

+C6orf132chr6

42078029

-
5CDS-intronENST00000393713ENST00000356542RNF121chr11

71671937

+C6orf132chr6

42078029

-
5CDS-intronENST00000530137ENST00000356542RNF121chr11

71671937

+C6orf132chr6

42078029

-
5CDS-intronENST00000533380ENST00000356542RNF121chr11

71671937

+C6orf132chr6

42078029

-
5UTR-3CDSENST00000545854ENST00000341865RNF121chr11

71671937

+C6orf132chr6

42078029

-
5UTR-intronENST00000545854ENST00000356542RNF121chr11

71671937

+C6orf132chr6

42078029

-
In-frameENST00000361756ENST00000341865RNF121chr11

71671937

+C6orf132chr6

42078029

-
In-frameENST00000393713ENST00000341865RNF121chr11

71671937

+C6orf132chr6

42078029

-
In-frameENST00000530137ENST00000341865RNF121chr11

71671937

+C6orf132chr6

42078029

-
In-frameENST00000533380ENST00000341865RNF121chr11

71671937

+C6orf132chr6

42078029

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000361756RNF121chr1171671937+ENST00000341865C6orf132chr642078029-656260431939181199
ENST00000533380RNF121chr1171671937+ENST00000341865C6orf132chr642078029-61932355535491164
ENST00000393713RNF121chr1171671937+ENST00000341865C6orf132chr642078029-61912335335471164
ENST00000530137RNF121chr1171671937+ENST00000341865C6orf132chr642078029-6143185534991164

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000361756ENST00000341865RNF121chr1171671937+C6orf132chr642078029-0.0024281090.9975719
ENST00000533380ENST00000341865RNF121chr1171671937+C6orf132chr642078029-0.0019670780.99803287
ENST00000393713ENST00000341865RNF121chr1171671937+C6orf132chr642078029-0.0019586980.9980413
ENST00000530137ENST00000341865RNF121chr1171671937+C6orf132chr642078029-0.0018581020.9981419

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Fusion Genomic Features for RNF121-C6orf132


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RNF121-C6orf132


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:71671937/chr6:42078029)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.C6orf132

Q5T0Z8

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF121chr11:71671937chr6:42078029ENST00000361756+3950_7081328.0TransmembraneHelical
TgeneC6orf132chr11:71671937chr6:42078029ENST0000034186515140_185841189.0Compositional biasNote=Pro-rich
TgeneC6orf132chr11:71671937chr6:42078029ENST0000035654203140_1850100.0Compositional biasNote=Pro-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF121chr11:71671937chr6:42078029ENST00000361756+39100_12081328.0TransmembraneHelical
HgeneRNF121chr11:71671937chr6:42078029ENST00000361756+39148_16881328.0TransmembraneHelical
HgeneRNF121chr11:71671937chr6:42078029ENST00000361756+39172_19281328.0TransmembraneHelical
HgeneRNF121chr11:71671937chr6:42078029ENST00000361756+39306_32681328.0TransmembraneHelical
HgeneRNF121chr11:71671937chr6:42078029ENST00000361756+3979_9981328.0TransmembraneHelical
HgeneRNF121chr11:71671937chr6:42078029ENST00000361756+39226_27681328.0Zinc fingerRING-type%3B atypical


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Fusion Gene Sequence for RNF121-C6orf132


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>74726_74726_1_RNF121-C6orf132_RNF121_chr11_71671937_ENST00000361756_C6orf132_chr6_42078029_ENST00000341865_length(transcript)=6562nt_BP=604nt
ACGTCTCGCTCCTTGGAGCCCAGACTGAGGGAGCGTCGCGAAAGTTGCCCGTTTTGGAACGCTCCCATTTGGCTCTCCAAAGGGAAGAAT
TGGTTAAATAGTTGCACTGAAAATAATGCGATTCAAATTTCTCATTTTCCAAGAACGCTCCCTTGCTGAAGCTTGCAAGGGCACGGTACT
CCCCTCTCCTTGACCCTGAAACGTGCAGCAAGTAGATAACCTCCTGATCCCTGACAGTCTCCGCCTGTGTTGATGCCCCGCCCCCTCTGC
TGGAGTCCGAGCCGCCGATTGGCTAGGAGCACTTGAGCAGCGGAAGCAGCTGGCTCGCGCGGGGACTGCGGTGAGGGGGCGAGCCGTGAA
GATGGCGGCAGTGGTGGAGGTGGAGGTTGGAGGTGGTGCTGCTGGGGAACGGGAGCTGGATGAGGTTGATATGTCAGATCTCTCTCCAGA
AGAGCAATGGAGGGTCGAGCACGCACGCATGCATGCCAAGCACCGTGGCCATGAAGCTATGCATGCTGAAATGGTCCTCATCCTCATCGC
AACCTTGGTGGTGGCCCAGCTGCTCCTGGTGCAGTGGAAGCAGAGGCACCCACGCTCCTACAATAATGCCCAGGAAAACCATGGGCTGGC
TGTGCCCACCCCCTCGGTTCCAGATGATTTTGCAGACAAAGAAGTGACAGGTACCAGCTCACTAGTCAATGGCAACCTCCGACTGTACAG
CTCTGTGGGTGACCTGAGGCCTGGACAATATGGCCAGGATCTACTCATCCCCCCACCTCCCCCAGGCCCAGCCCCAGGGCCCCCTCAGGA
CATTTCAGAACCTCCAGGGGGGTCGCCACTGCCATCTCCACCTTCCACAGCACCCCCACCACCTCCCCTGCTGCTGGAACCCCCACCCCC
GCCCAGCATGGCCCCACCTCCACCCCCAGTATTGGAGGCCCTATCCCCACCACACACTCTTTCCTCCCCATCCATACCCACCCCTCCTGA
CTTCATTCCCCCTGCCCCACCCTTGGCCTTTCTAGCCCCCCCACCGCCTCCTGTGCCAGCCCCAGCACCCCCAGCTCCAGCATCTCCTCA
CACAGTGGGGACTCGTCTCTTTCCCCCTGGGGGTGTCACCAAGTGGAAATCAGATGTAGCACTGAATGGCAGGCAGGCAGAGGCCACCAG
AGCCAGCCCCCCGAGAAGCCCTGCTGAGCCAAAGGGGAGCGCCCTGGGACCTAACCCAGAGCCCCATCTCACCTTCCCCCGTTCTTTCAA
AGTGCCTCCCCCAACCCCAGTCAGGACTTCGTCCATCCCAGTTCAGGAAGCACAAGAGGCTCCCCGAAAGGAAGAGGGGGCCACCAAGAA
GGCTCCCAGCCGACTCCCACTGCCTCCCAGCTTCCACATCCGCCCCGCCTCCCAGGTCTACCCAGACAGGGCCCCCGAGCCAGACTGCCC
TGGGGAGCTCAAGGCCACAGCACCAGCCAGCCCAAGGCTTGGCCAGTCCCAGTCCCAAGCAGATGAACGAGCTGGGACTCCGCCTCCAGC
CCCTCCCCTGCCCCCTCCTGCACCCCCCCTCCCTCCCCCAGCACCCCCACTTCCCCCAGCTGCACCTCCTTTGCCCTGTGCTCAGAAGGC
AGCCCATCCACCTGCTGGGTTTACAAAAACCCCTAAATCCAGCTCTCCTGCTCTCAAACCCAAACCCAACCCCCCCAGCCCAGAGAACAC
AGCGTCTTCAGCACCTGTGGACTGGAGGGACCCCAGCCAGATGGAAAAGCTGCGGAACGAGCTGGCAGCCTATCTCTGTGGCTCCAGGAG
AGAGGACCGATTCCTCAGTCACAGGCCAGGCCCAACAGTGGCCCCTCAGAGCAAGGAGGGCAAGAAGGGCCCCCGCCTGCCTGAGAAGGA
GACTCTCCTGAGCCTGCCAGCAAAGGACACTCCCCCAGGTGTTCCTGAAAAGAGTCTTGGCGGCAGCAGCCTGACAGAGACAGAGGCTGC
CCCCAGCCTGACCCTGCCCTCTGTGGACTACATTCCCCAAGACTCTCCAACTCCCAGTGTGCGGCAGATCCGGAATGAGCTGGAGGCCCG
GCTCTCCTCAGCAGCAGAGAAGGAGGCTAAGCCCAGCATAGGATCTCTGCCCCCTAAGCCTCGGCTAGAAGGGGGAAGAATTTGTGAAAA
CGGGGCTGATGATGACAAACTCTCCAAGCCTGTGGCCAAGAATCTGCCACCTCAATCCACCACCCTGCTGCCAACTACATCACTCCAGCC
CAAGGCTATGTTGGGACCAGCCATACCACCCAAGGCCACACCTGAGCCAGCCATACCACCCAAGGCTACACTTTGGCCAGCCACACCACC
CAAGGCCACACTTGGGCCAGCCACACCACTCAAGGCCACATCTGGGCCAACCACACCACTCAAGGCCACATCTGGCCCTGCCATAGCATC
TACAGCCACAACTCTGCCCACCACCACATCCCAACTGATGGCAGAGAAGGACTCAGGCCCAGCTGGCCAGCCAGAGAAGCCAGCATCTCA
AGAAGTTTCCACTCCCTCCCAGGCAAGGGGAGAGGGGTCCCCCTCAGAGGCCACTAGGCTGCCCACACAGGGAGCCCGCTCATCTGCAGC
CTTCCCACCAAAGACATCTCCTGGTGGAGGAGAGGTGCCATGTCTCTACAAGCCCCACTGCCACCAGAGCAGCCTCAGCCGTGAGGTTGC
TGTGGTGATGCCCACCCTGGCCAGAGGAGGGGCTGCAGGGCCAGGGGAGCCCGTGGAGGTGAAGGAGCCCCCAGGGCTGCCAGCCAAGCC
TCCTGCCTCGGCCCAGCCCACTGATGAACTCCTCAGGCACCCGGTGACTGGGGAGGTGGTGGAGCGGGGCTCGCCGATGGCCCTGCTCCT
GGCGGCCAGGCAGAGGGCTCAGAAGGGAAGGTCTGTAGGGGCTGCCCTGGGTCGGTCCTCTCTGCCAGGAAGTCTCCGTGACCACAGCCA
CCAAGCCGAGGCCAGCTCTGACAGCATCTTCCACAGCCAGGGCACGCCCAACTCCTTCACTGTGGTGCCCAAGTTACCCAAGGAGGCTGA
GAAGGACTCCCCGCTGACGACCGAAATACCCAATAAGTGGGGGCCGCGGCTGGGAAGAGACGCAGAGGGCACAGAGCTGAGCCGCAGGCA
CAACTGGACAAAGCCAGAGCCCCAGGCCCCTGTGGCCTGGGAAAGAGTAGCTCCCTCCAACCTCCCCCAGGGCCACCCGCTGCCCAAGTC
CTTCTCCTCCCCACCTTCTCCTTCGAACAAGAGGGAGGAGGAGGAGGAGGAGTTCAACTTCGAGGTCATCCCACCGCCGCCAGAGTTCAG
CAATGACCCTGAGCCCCCGGCCCCGGCCCTCCAGTATCTGGGCCGCCAGAGCTCCCCTCCCCGGAACAACTACTCAGACTTGAGGCAGCT
CCCGAACGCTGGCCCCGGGGCGCCCCCGGCTCTCGGCTTCTCGCGCTTTCCCGCGGGCGCGCGCTACGCCGGGGCTGGGGGCCTGGAGCG
CTTCTCGGGAGGGGGCCGCTCGCTCATAAAGAAGCGCCTGTACGTCGGGGAGCCGCACCGAGGCCCAGGGCTACCCCACGGTGGCACCGG
CCGCAGCCTGAGCTCTCCCAACTGCTTCGGGCCGCAGCCCGGAGGCCCCGAGATGCGGCGCGTGAACTCGGCGGGTCGCGCGCCCCCCGG
AGGCCTGCACGCGCCGAGGCTGTCCCTGGAGGGCGCCGCCCGGGGCGCCGCGGAGGCCAAGCACAAAGCGCCCGGCAGCGCCGACTACGG
CTTCGCCCCAGCTGCCGGCAGGTCTCCCTACACCACCACCCGCTATGGAAGCCCCATCAACACGTTCACCGTGAGGCCTGGGACCCGCCA
TCCCATCTCCTATGTCTGCTCAGGGGCCCATCGGAAAGCCACCTCCTGAGCCAGGGGTTCTCTTAGCTCTACTCCAACAAACTGTGTCTT
TAAGGATCTGGGCACTTGTTTCTTGTGGGGGGTGGGAGGTACACAGCAGGTGTTGGGCGACCTGACTCAGACACAGAGGAGTCTTTGATC
CCCAAAGACCAACGATGAGAAGCAGTGGCCCAGGAAGACCGAGAGTGGGCTTCTGTTTCCCAAAGCGCTGGTGTGACTGTGGACTGTTTA
CACGTGGGGGGTGGGAGGGGAAGGAGGGTAGAGAGAAGGAACCATTAAGGACCTGGGCGCTGAGTTTCTGCTCTCTGGTACTATCTGCTT
TAGCAAGAGTTATTTAAAACAGTTTTACAAGCACGGCCTACTGAGCAGGTTCTGAAAGCAAGGGGTGGGGCACTGACTGAACTGGAACCC
ATCGAGATAGCTGTGATTGCCTGTCAGGCCCTTGCAAAGGGCTGAGGCCCAGCTCTGTCTGGTGGGTGTGCAGGGCACCGAAGGGAGATC
TTTAGCCTCCATCACCTGCCATCCCAAGCAAGAGTGGACACCTGGGGTTCCTAGCCGCATTGAGGTGGGACCAGGAATGTGTATGTATAA
CATGTGGAGAAGGACCATGTGTGGGGTGGGGAGTGAAGCTCCCACATGTGGAATGGAAGCCCTTTGCATTGGCCAAGGGCAGAGGTGGGA
GATTGATGGTTCATTTTTCCTTGGCCCTAGCCCTTAGCTACAGGGAGGCCTAGAGAGAGGACACTTGGCAAGTTTAGGATGGGAAACAAG
GTTAAGCCTGGCTTTGCTATTCAGACCTGTGCAGCCCTGATTTTGGGGACTGGGCCCAAGGAGCCATGAGTCTTAGGCTTGACACTAGGG
GCCTTACATGGCCAGGTCTCATATGGGATTTGGAGAAGGCATTTTTCCTAACACTGATACTACAAGTCACCAATACTCTTGATGCCTTAA
GATGCTAGAAAGCCTTGGAGAGTGGAGGCAGCAGAGATGGGAATGGAGGTCTGAAGAAGCTTGCTGCTGTTGGGGAATGTGTTTGGGAAA
GTCAAGAGTGGTAGGATTGGTTGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCCGGTGGATCACTTGA
GGTCAGAAGTTCGAGACCAGCCTGCCCAAATGGTGAAACCCCATCTCTACTAAAAATACGGAAAAAAAAAAAAAAAGAGTGCTAGGATTG
GGCCAGTTAAGAGCAGGGGAGACCTGGCTGGGCATGGTGGCTCACACCTGTAATTCTAGCACTTTGGGAGGCTGAGGCGGGTGGATCATG
AGGTCAAGAGATTAAGACCATCCTGGCCTACATGGCGAAACCCTGTCTCTACTAAAAATAAAAAAATGACCTGGGCATGGTGGTGGGCGC
CTGTAGTCCCAGCTACTCGGGGCGCTGAGGCAGGAGAATCGCTCGAACCCAGGAGGTGGAGGTTGCAGTGAGCCGAGATTGCACAATTGC
ACTCCAGCCTGGCGACAGAGCGAGACTCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAGGAGCAGGGGAGACCTATCAGTAGGGTGACCA
CGTGTCCTTTGCCTGGGCAGTCCAGGTTTATGCTTGTTTTCCAGTGAATTAGACCCCCTTCCACTTTTCAAAAAAGTCCTGGTTTAGATG
CTGTGATCACCAAACATATCAGGAAACAATATTCCTTGGTCTTGCTTCCCTATCTTCAGGTACTGGTGGGCCAAATTCCTGGGACCAGGT
CAAGGTGGGCTGCCTCAGTAAGAAGGAAGGACTGGAGAGTGCCCATTTCAGAGGAGCAGGCTGGTGGGGGCCAGCCAGAAAGTAGTTCCC
TTTGGGGGGAAGATGTTGGACCTTTATTATTTGTGGTAACCAGCCGAGGCTGGTTGTCAGGACAGCAGGTGAGCCACTTTAGGGAAGAAA
GTGCAGGGGTGGGTGGATGCCCAGATTACCAAGGCCAGCCACCCTGATGGGGTAGGGTCTGGTTATCTGTGTTCAAGAAGCAAATCCCAC
CCCAGCCCCAGCACTAGCTCTCTATGTATGTATTTTCCCTGTACAATGTTTTATAAAAGAGATCATTAATTTATCTGCTATGTTAAGGCT
CGAGGGGTGGGGCGTAGACTCTCAGCTGTATATTGCTCTGGGGTGGGCAGGGAAGGCTGAGTCTCACTTGACTTGGAAGATAAACAGGCC
AGTTTGGACTGGCCTCCAGCTCCGTGGCTGTGTTTGTCTAACAAGGATTTGGGTAACTACTGGATACAAGCCACTGTGCTTAGTATGGAT
AGACTGCCATCAGCTCACCCACATGACTCCTGTTCATGGCAAGCTAATAGTCTGTCTGGTGGAAGAGGATTGAAAAAGCACACAAAAACA
TCATAAATTACAAGGAGTAGTAAGAAGGAAAAAACAGGGAACGTGAGAGAATAACTAGCGAGTGGGGAGAGGAGTGGATTTACTTTAACA
GGGTAGTCAGGGAAGGCCTCTTGTGGTGGTGACATACTGATTTAGGCAAAGCGTCCAGCACGTGCCTAGCGCTTAGTAGTTGCTCAGCAA

>74726_74726_1_RNF121-C6orf132_RNF121_chr11_71671937_ENST00000361756_C6orf132_chr6_42078029_ENST00000341865_length(amino acids)=1199AA_BP=170
MARAGTAVRGRAVKMAAVVEVEVGGGAAGERELDEVDMSDLSPEEQWRVEHARMHAKHRGHEAMHAEMVLILIATLVVAQLLLVQWKQRH
PRSYNNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPST
APPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWK
SDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPA
SQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSP
ALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPE
KSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLP
PQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEK
DSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGE
PVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTP
NSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEE
EFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVG
EPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAPAAGRSPYTTTRYG

--------------------------------------------------------------
>74726_74726_2_RNF121-C6orf132_RNF121_chr11_71671937_ENST00000393713_C6orf132_chr6_42078029_ENST00000341865_length(transcript)=6191nt_BP=233nt
GACTGCGGTGAGGGGGCGAGCCGTGAAGATGGCGGCAGTGGTGGAGGTGGAGGTTGGAGGTGGTGCTGCTGGGGAACGGGAGCTGGATGA
GGGTCGAGCACGCACGCATGCATGCCAAGCACCGTGGCCATGAAGCTATGCATGCTGAAATGGTCCTCATCCTCATCGCAACCTTGGTGG
TGGCCCAGCTGCTCCTGGTGCAGTGGAAGCAGAGGCACCCACGCTCCTACAATAATGCCCAGGAAAACCATGGGCTGGCTGTGCCCACCC
CCTCGGTTCCAGATGATTTTGCAGACAAAGAAGTGACAGGTACCAGCTCACTAGTCAATGGCAACCTCCGACTGTACAGCTCTGTGGGTG
ACCTGAGGCCTGGACAATATGGCCAGGATCTACTCATCCCCCCACCTCCCCCAGGCCCAGCCCCAGGGCCCCCTCAGGACATTTCAGAAC
CTCCAGGGGGGTCGCCACTGCCATCTCCACCTTCCACAGCACCCCCACCACCTCCCCTGCTGCTGGAACCCCCACCCCCGCCCAGCATGG
CCCCACCTCCACCCCCAGTATTGGAGGCCCTATCCCCACCACACACTCTTTCCTCCCCATCCATACCCACCCCTCCTGACTTCATTCCCC
CTGCCCCACCCTTGGCCTTTCTAGCCCCCCCACCGCCTCCTGTGCCAGCCCCAGCACCCCCAGCTCCAGCATCTCCTCACACAGTGGGGA
CTCGTCTCTTTCCCCCTGGGGGTGTCACCAAGTGGAAATCAGATGTAGCACTGAATGGCAGGCAGGCAGAGGCCACCAGAGCCAGCCCCC
CGAGAAGCCCTGCTGAGCCAAAGGGGAGCGCCCTGGGACCTAACCCAGAGCCCCATCTCACCTTCCCCCGTTCTTTCAAAGTGCCTCCCC
CAACCCCAGTCAGGACTTCGTCCATCCCAGTTCAGGAAGCACAAGAGGCTCCCCGAAAGGAAGAGGGGGCCACCAAGAAGGCTCCCAGCC
GACTCCCACTGCCTCCCAGCTTCCACATCCGCCCCGCCTCCCAGGTCTACCCAGACAGGGCCCCCGAGCCAGACTGCCCTGGGGAGCTCA
AGGCCACAGCACCAGCCAGCCCAAGGCTTGGCCAGTCCCAGTCCCAAGCAGATGAACGAGCTGGGACTCCGCCTCCAGCCCCTCCCCTGC
CCCCTCCTGCACCCCCCCTCCCTCCCCCAGCACCCCCACTTCCCCCAGCTGCACCTCCTTTGCCCTGTGCTCAGAAGGCAGCCCATCCAC
CTGCTGGGTTTACAAAAACCCCTAAATCCAGCTCTCCTGCTCTCAAACCCAAACCCAACCCCCCCAGCCCAGAGAACACAGCGTCTTCAG
CACCTGTGGACTGGAGGGACCCCAGCCAGATGGAAAAGCTGCGGAACGAGCTGGCAGCCTATCTCTGTGGCTCCAGGAGAGAGGACCGAT
TCCTCAGTCACAGGCCAGGCCCAACAGTGGCCCCTCAGAGCAAGGAGGGCAAGAAGGGCCCCCGCCTGCCTGAGAAGGAGACTCTCCTGA
GCCTGCCAGCAAAGGACACTCCCCCAGGTGTTCCTGAAAAGAGTCTTGGCGGCAGCAGCCTGACAGAGACAGAGGCTGCCCCCAGCCTGA
CCCTGCCCTCTGTGGACTACATTCCCCAAGACTCTCCAACTCCCAGTGTGCGGCAGATCCGGAATGAGCTGGAGGCCCGGCTCTCCTCAG
CAGCAGAGAAGGAGGCTAAGCCCAGCATAGGATCTCTGCCCCCTAAGCCTCGGCTAGAAGGGGGAAGAATTTGTGAAAACGGGGCTGATG
ATGACAAACTCTCCAAGCCTGTGGCCAAGAATCTGCCACCTCAATCCACCACCCTGCTGCCAACTACATCACTCCAGCCCAAGGCTATGT
TGGGACCAGCCATACCACCCAAGGCCACACCTGAGCCAGCCATACCACCCAAGGCTACACTTTGGCCAGCCACACCACCCAAGGCCACAC
TTGGGCCAGCCACACCACTCAAGGCCACATCTGGGCCAACCACACCACTCAAGGCCACATCTGGCCCTGCCATAGCATCTACAGCCACAA
CTCTGCCCACCACCACATCCCAACTGATGGCAGAGAAGGACTCAGGCCCAGCTGGCCAGCCAGAGAAGCCAGCATCTCAAGAAGTTTCCA
CTCCCTCCCAGGCAAGGGGAGAGGGGTCCCCCTCAGAGGCCACTAGGCTGCCCACACAGGGAGCCCGCTCATCTGCAGCCTTCCCACCAA
AGACATCTCCTGGTGGAGGAGAGGTGCCATGTCTCTACAAGCCCCACTGCCACCAGAGCAGCCTCAGCCGTGAGGTTGCTGTGGTGATGC
CCACCCTGGCCAGAGGAGGGGCTGCAGGGCCAGGGGAGCCCGTGGAGGTGAAGGAGCCCCCAGGGCTGCCAGCCAAGCCTCCTGCCTCGG
CCCAGCCCACTGATGAACTCCTCAGGCACCCGGTGACTGGGGAGGTGGTGGAGCGGGGCTCGCCGATGGCCCTGCTCCTGGCGGCCAGGC
AGAGGGCTCAGAAGGGAAGGTCTGTAGGGGCTGCCCTGGGTCGGTCCTCTCTGCCAGGAAGTCTCCGTGACCACAGCCACCAAGCCGAGG
CCAGCTCTGACAGCATCTTCCACAGCCAGGGCACGCCCAACTCCTTCACTGTGGTGCCCAAGTTACCCAAGGAGGCTGAGAAGGACTCCC
CGCTGACGACCGAAATACCCAATAAGTGGGGGCCGCGGCTGGGAAGAGACGCAGAGGGCACAGAGCTGAGCCGCAGGCACAACTGGACAA
AGCCAGAGCCCCAGGCCCCTGTGGCCTGGGAAAGAGTAGCTCCCTCCAACCTCCCCCAGGGCCACCCGCTGCCCAAGTCCTTCTCCTCCC
CACCTTCTCCTTCGAACAAGAGGGAGGAGGAGGAGGAGGAGTTCAACTTCGAGGTCATCCCACCGCCGCCAGAGTTCAGCAATGACCCTG
AGCCCCCGGCCCCGGCCCTCCAGTATCTGGGCCGCCAGAGCTCCCCTCCCCGGAACAACTACTCAGACTTGAGGCAGCTCCCGAACGCTG
GCCCCGGGGCGCCCCCGGCTCTCGGCTTCTCGCGCTTTCCCGCGGGCGCGCGCTACGCCGGGGCTGGGGGCCTGGAGCGCTTCTCGGGAG
GGGGCCGCTCGCTCATAAAGAAGCGCCTGTACGTCGGGGAGCCGCACCGAGGCCCAGGGCTACCCCACGGTGGCACCGGCCGCAGCCTGA
GCTCTCCCAACTGCTTCGGGCCGCAGCCCGGAGGCCCCGAGATGCGGCGCGTGAACTCGGCGGGTCGCGCGCCCCCCGGAGGCCTGCACG
CGCCGAGGCTGTCCCTGGAGGGCGCCGCCCGGGGCGCCGCGGAGGCCAAGCACAAAGCGCCCGGCAGCGCCGACTACGGCTTCGCCCCAG
CTGCCGGCAGGTCTCCCTACACCACCACCCGCTATGGAAGCCCCATCAACACGTTCACCGTGAGGCCTGGGACCCGCCATCCCATCTCCT
ATGTCTGCTCAGGGGCCCATCGGAAAGCCACCTCCTGAGCCAGGGGTTCTCTTAGCTCTACTCCAACAAACTGTGTCTTTAAGGATCTGG
GCACTTGTTTCTTGTGGGGGGTGGGAGGTACACAGCAGGTGTTGGGCGACCTGACTCAGACACAGAGGAGTCTTTGATCCCCAAAGACCA
ACGATGAGAAGCAGTGGCCCAGGAAGACCGAGAGTGGGCTTCTGTTTCCCAAAGCGCTGGTGTGACTGTGGACTGTTTACACGTGGGGGG
TGGGAGGGGAAGGAGGGTAGAGAGAAGGAACCATTAAGGACCTGGGCGCTGAGTTTCTGCTCTCTGGTACTATCTGCTTTAGCAAGAGTT
ATTTAAAACAGTTTTACAAGCACGGCCTACTGAGCAGGTTCTGAAAGCAAGGGGTGGGGCACTGACTGAACTGGAACCCATCGAGATAGC
TGTGATTGCCTGTCAGGCCCTTGCAAAGGGCTGAGGCCCAGCTCTGTCTGGTGGGTGTGCAGGGCACCGAAGGGAGATCTTTAGCCTCCA
TCACCTGCCATCCCAAGCAAGAGTGGACACCTGGGGTTCCTAGCCGCATTGAGGTGGGACCAGGAATGTGTATGTATAACATGTGGAGAA
GGACCATGTGTGGGGTGGGGAGTGAAGCTCCCACATGTGGAATGGAAGCCCTTTGCATTGGCCAAGGGCAGAGGTGGGAGATTGATGGTT
CATTTTTCCTTGGCCCTAGCCCTTAGCTACAGGGAGGCCTAGAGAGAGGACACTTGGCAAGTTTAGGATGGGAAACAAGGTTAAGCCTGG
CTTTGCTATTCAGACCTGTGCAGCCCTGATTTTGGGGACTGGGCCCAAGGAGCCATGAGTCTTAGGCTTGACACTAGGGGCCTTACATGG
CCAGGTCTCATATGGGATTTGGAGAAGGCATTTTTCCTAACACTGATACTACAAGTCACCAATACTCTTGATGCCTTAAGATGCTAGAAA
GCCTTGGAGAGTGGAGGCAGCAGAGATGGGAATGGAGGTCTGAAGAAGCTTGCTGCTGTTGGGGAATGTGTTTGGGAAAGTCAAGAGTGG
TAGGATTGGTTGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCCGGTGGATCACTTGAGGTCAGAAGTT
CGAGACCAGCCTGCCCAAATGGTGAAACCCCATCTCTACTAAAAATACGGAAAAAAAAAAAAAAAGAGTGCTAGGATTGGGCCAGTTAAG
AGCAGGGGAGACCTGGCTGGGCATGGTGGCTCACACCTGTAATTCTAGCACTTTGGGAGGCTGAGGCGGGTGGATCATGAGGTCAAGAGA
TTAAGACCATCCTGGCCTACATGGCGAAACCCTGTCTCTACTAAAAATAAAAAAATGACCTGGGCATGGTGGTGGGCGCCTGTAGTCCCA
GCTACTCGGGGCGCTGAGGCAGGAGAATCGCTCGAACCCAGGAGGTGGAGGTTGCAGTGAGCCGAGATTGCACAATTGCACTCCAGCCTG
GCGACAGAGCGAGACTCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAGGAGCAGGGGAGACCTATCAGTAGGGTGACCACGTGTCCTTTG
CCTGGGCAGTCCAGGTTTATGCTTGTTTTCCAGTGAATTAGACCCCCTTCCACTTTTCAAAAAAGTCCTGGTTTAGATGCTGTGATCACC
AAACATATCAGGAAACAATATTCCTTGGTCTTGCTTCCCTATCTTCAGGTACTGGTGGGCCAAATTCCTGGGACCAGGTCAAGGTGGGCT
GCCTCAGTAAGAAGGAAGGACTGGAGAGTGCCCATTTCAGAGGAGCAGGCTGGTGGGGGCCAGCCAGAAAGTAGTTCCCTTTGGGGGGAA
GATGTTGGACCTTTATTATTTGTGGTAACCAGCCGAGGCTGGTTGTCAGGACAGCAGGTGAGCCACTTTAGGGAAGAAAGTGCAGGGGTG
GGTGGATGCCCAGATTACCAAGGCCAGCCACCCTGATGGGGTAGGGTCTGGTTATCTGTGTTCAAGAAGCAAATCCCACCCCAGCCCCAG
CACTAGCTCTCTATGTATGTATTTTCCCTGTACAATGTTTTATAAAAGAGATCATTAATTTATCTGCTATGTTAAGGCTCGAGGGGTGGG
GCGTAGACTCTCAGCTGTATATTGCTCTGGGGTGGGCAGGGAAGGCTGAGTCTCACTTGACTTGGAAGATAAACAGGCCAGTTTGGACTG
GCCTCCAGCTCCGTGGCTGTGTTTGTCTAACAAGGATTTGGGTAACTACTGGATACAAGCCACTGTGCTTAGTATGGATAGACTGCCATC
AGCTCACCCACATGACTCCTGTTCATGGCAAGCTAATAGTCTGTCTGGTGGAAGAGGATTGAAAAAGCACACAAAAACATCATAAATTAC
AAGGAGTAGTAAGAAGGAAAAAACAGGGAACGTGAGAGAATAACTAGCGAGTGGGGAGAGGAGTGGATTTACTTTAACAGGGTAGTCAGG
GAAGGCCTCTTGTGGTGGTGACATACTGATTTAGGCAAAGCGTCCAGCACGTGCCTAGCGCTTAGTAGTTGCTCAGCAAATGGCATCTTT

>74726_74726_2_RNF121-C6orf132_RNF121_chr11_71671937_ENST00000393713_C6orf132_chr6_42078029_ENST00000341865_length(amino acids)=1164AA_BP=135
MEVVLLGNGSWMRVEHARMHAKHRGHEAMHAEMVLILIATLVVAQLLLVQWKQRHPRSYNNAQENHGLAVPTPSVPDDFADKEVTGTSSL
VNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLS
SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEP
HLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQAD
ERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNEL
AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVR
QIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPK
ATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLP
TQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVE
RGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDA
EGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR
NNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRV

--------------------------------------------------------------
>74726_74726_3_RNF121-C6orf132_RNF121_chr11_71671937_ENST00000530137_C6orf132_chr6_42078029_ENST00000341865_length(transcript)=6143nt_BP=185nt
GGAGGTTGGAGGTGGTGCTGCTGGGGAACGGGAGCTGGATGAGGGTCGAGCACGCACGCATGCATGCCAAGCACCGTGGCCATGAAGCTA
TGCATGCTGAAATGGTCCTCATCCTCATCGCAACCTTGGTGGTGGCCCAGCTGCTCCTGGTGCAGTGGAAGCAGAGGCACCCACGCTCCT
ACAATAATGCCCAGGAAAACCATGGGCTGGCTGTGCCCACCCCCTCGGTTCCAGATGATTTTGCAGACAAAGAAGTGACAGGTACCAGCT
CACTAGTCAATGGCAACCTCCGACTGTACAGCTCTGTGGGTGACCTGAGGCCTGGACAATATGGCCAGGATCTACTCATCCCCCCACCTC
CCCCAGGCCCAGCCCCAGGGCCCCCTCAGGACATTTCAGAACCTCCAGGGGGGTCGCCACTGCCATCTCCACCTTCCACAGCACCCCCAC
CACCTCCCCTGCTGCTGGAACCCCCACCCCCGCCCAGCATGGCCCCACCTCCACCCCCAGTATTGGAGGCCCTATCCCCACCACACACTC
TTTCCTCCCCATCCATACCCACCCCTCCTGACTTCATTCCCCCTGCCCCACCCTTGGCCTTTCTAGCCCCCCCACCGCCTCCTGTGCCAG
CCCCAGCACCCCCAGCTCCAGCATCTCCTCACACAGTGGGGACTCGTCTCTTTCCCCCTGGGGGTGTCACCAAGTGGAAATCAGATGTAG
CACTGAATGGCAGGCAGGCAGAGGCCACCAGAGCCAGCCCCCCGAGAAGCCCTGCTGAGCCAAAGGGGAGCGCCCTGGGACCTAACCCAG
AGCCCCATCTCACCTTCCCCCGTTCTTTCAAAGTGCCTCCCCCAACCCCAGTCAGGACTTCGTCCATCCCAGTTCAGGAAGCACAAGAGG
CTCCCCGAAAGGAAGAGGGGGCCACCAAGAAGGCTCCCAGCCGACTCCCACTGCCTCCCAGCTTCCACATCCGCCCCGCCTCCCAGGTCT
ACCCAGACAGGGCCCCCGAGCCAGACTGCCCTGGGGAGCTCAAGGCCACAGCACCAGCCAGCCCAAGGCTTGGCCAGTCCCAGTCCCAAG
CAGATGAACGAGCTGGGACTCCGCCTCCAGCCCCTCCCCTGCCCCCTCCTGCACCCCCCCTCCCTCCCCCAGCACCCCCACTTCCCCCAG
CTGCACCTCCTTTGCCCTGTGCTCAGAAGGCAGCCCATCCACCTGCTGGGTTTACAAAAACCCCTAAATCCAGCTCTCCTGCTCTCAAAC
CCAAACCCAACCCCCCCAGCCCAGAGAACACAGCGTCTTCAGCACCTGTGGACTGGAGGGACCCCAGCCAGATGGAAAAGCTGCGGAACG
AGCTGGCAGCCTATCTCTGTGGCTCCAGGAGAGAGGACCGATTCCTCAGTCACAGGCCAGGCCCAACAGTGGCCCCTCAGAGCAAGGAGG
GCAAGAAGGGCCCCCGCCTGCCTGAGAAGGAGACTCTCCTGAGCCTGCCAGCAAAGGACACTCCCCCAGGTGTTCCTGAAAAGAGTCTTG
GCGGCAGCAGCCTGACAGAGACAGAGGCTGCCCCCAGCCTGACCCTGCCCTCTGTGGACTACATTCCCCAAGACTCTCCAACTCCCAGTG
TGCGGCAGATCCGGAATGAGCTGGAGGCCCGGCTCTCCTCAGCAGCAGAGAAGGAGGCTAAGCCCAGCATAGGATCTCTGCCCCCTAAGC
CTCGGCTAGAAGGGGGAAGAATTTGTGAAAACGGGGCTGATGATGACAAACTCTCCAAGCCTGTGGCCAAGAATCTGCCACCTCAATCCA
CCACCCTGCTGCCAACTACATCACTCCAGCCCAAGGCTATGTTGGGACCAGCCATACCACCCAAGGCCACACCTGAGCCAGCCATACCAC
CCAAGGCTACACTTTGGCCAGCCACACCACCCAAGGCCACACTTGGGCCAGCCACACCACTCAAGGCCACATCTGGGCCAACCACACCAC
TCAAGGCCACATCTGGCCCTGCCATAGCATCTACAGCCACAACTCTGCCCACCACCACATCCCAACTGATGGCAGAGAAGGACTCAGGCC
CAGCTGGCCAGCCAGAGAAGCCAGCATCTCAAGAAGTTTCCACTCCCTCCCAGGCAAGGGGAGAGGGGTCCCCCTCAGAGGCCACTAGGC
TGCCCACACAGGGAGCCCGCTCATCTGCAGCCTTCCCACCAAAGACATCTCCTGGTGGAGGAGAGGTGCCATGTCTCTACAAGCCCCACT
GCCACCAGAGCAGCCTCAGCCGTGAGGTTGCTGTGGTGATGCCCACCCTGGCCAGAGGAGGGGCTGCAGGGCCAGGGGAGCCCGTGGAGG
TGAAGGAGCCCCCAGGGCTGCCAGCCAAGCCTCCTGCCTCGGCCCAGCCCACTGATGAACTCCTCAGGCACCCGGTGACTGGGGAGGTGG
TGGAGCGGGGCTCGCCGATGGCCCTGCTCCTGGCGGCCAGGCAGAGGGCTCAGAAGGGAAGGTCTGTAGGGGCTGCCCTGGGTCGGTCCT
CTCTGCCAGGAAGTCTCCGTGACCACAGCCACCAAGCCGAGGCCAGCTCTGACAGCATCTTCCACAGCCAGGGCACGCCCAACTCCTTCA
CTGTGGTGCCCAAGTTACCCAAGGAGGCTGAGAAGGACTCCCCGCTGACGACCGAAATACCCAATAAGTGGGGGCCGCGGCTGGGAAGAG
ACGCAGAGGGCACAGAGCTGAGCCGCAGGCACAACTGGACAAAGCCAGAGCCCCAGGCCCCTGTGGCCTGGGAAAGAGTAGCTCCCTCCA
ACCTCCCCCAGGGCCACCCGCTGCCCAAGTCCTTCTCCTCCCCACCTTCTCCTTCGAACAAGAGGGAGGAGGAGGAGGAGGAGTTCAACT
TCGAGGTCATCCCACCGCCGCCAGAGTTCAGCAATGACCCTGAGCCCCCGGCCCCGGCCCTCCAGTATCTGGGCCGCCAGAGCTCCCCTC
CCCGGAACAACTACTCAGACTTGAGGCAGCTCCCGAACGCTGGCCCCGGGGCGCCCCCGGCTCTCGGCTTCTCGCGCTTTCCCGCGGGCG
CGCGCTACGCCGGGGCTGGGGGCCTGGAGCGCTTCTCGGGAGGGGGCCGCTCGCTCATAAAGAAGCGCCTGTACGTCGGGGAGCCGCACC
GAGGCCCAGGGCTACCCCACGGTGGCACCGGCCGCAGCCTGAGCTCTCCCAACTGCTTCGGGCCGCAGCCCGGAGGCCCCGAGATGCGGC
GCGTGAACTCGGCGGGTCGCGCGCCCCCCGGAGGCCTGCACGCGCCGAGGCTGTCCCTGGAGGGCGCCGCCCGGGGCGCCGCGGAGGCCA
AGCACAAAGCGCCCGGCAGCGCCGACTACGGCTTCGCCCCAGCTGCCGGCAGGTCTCCCTACACCACCACCCGCTATGGAAGCCCCATCA
ACACGTTCACCGTGAGGCCTGGGACCCGCCATCCCATCTCCTATGTCTGCTCAGGGGCCCATCGGAAAGCCACCTCCTGAGCCAGGGGTT
CTCTTAGCTCTACTCCAACAAACTGTGTCTTTAAGGATCTGGGCACTTGTTTCTTGTGGGGGGTGGGAGGTACACAGCAGGTGTTGGGCG
ACCTGACTCAGACACAGAGGAGTCTTTGATCCCCAAAGACCAACGATGAGAAGCAGTGGCCCAGGAAGACCGAGAGTGGGCTTCTGTTTC
CCAAAGCGCTGGTGTGACTGTGGACTGTTTACACGTGGGGGGTGGGAGGGGAAGGAGGGTAGAGAGAAGGAACCATTAAGGACCTGGGCG
CTGAGTTTCTGCTCTCTGGTACTATCTGCTTTAGCAAGAGTTATTTAAAACAGTTTTACAAGCACGGCCTACTGAGCAGGTTCTGAAAGC
AAGGGGTGGGGCACTGACTGAACTGGAACCCATCGAGATAGCTGTGATTGCCTGTCAGGCCCTTGCAAAGGGCTGAGGCCCAGCTCTGTC
TGGTGGGTGTGCAGGGCACCGAAGGGAGATCTTTAGCCTCCATCACCTGCCATCCCAAGCAAGAGTGGACACCTGGGGTTCCTAGCCGCA
TTGAGGTGGGACCAGGAATGTGTATGTATAACATGTGGAGAAGGACCATGTGTGGGGTGGGGAGTGAAGCTCCCACATGTGGAATGGAAG
CCCTTTGCATTGGCCAAGGGCAGAGGTGGGAGATTGATGGTTCATTTTTCCTTGGCCCTAGCCCTTAGCTACAGGGAGGCCTAGAGAGAG
GACACTTGGCAAGTTTAGGATGGGAAACAAGGTTAAGCCTGGCTTTGCTATTCAGACCTGTGCAGCCCTGATTTTGGGGACTGGGCCCAA
GGAGCCATGAGTCTTAGGCTTGACACTAGGGGCCTTACATGGCCAGGTCTCATATGGGATTTGGAGAAGGCATTTTTCCTAACACTGATA
CTACAAGTCACCAATACTCTTGATGCCTTAAGATGCTAGAAAGCCTTGGAGAGTGGAGGCAGCAGAGATGGGAATGGAGGTCTGAAGAAG
CTTGCTGCTGTTGGGGAATGTGTTTGGGAAAGTCAAGAGTGGTAGGATTGGTTGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCAC
TTTGGGAGGCCGAGGCCGGTGGATCACTTGAGGTCAGAAGTTCGAGACCAGCCTGCCCAAATGGTGAAACCCCATCTCTACTAAAAATAC
GGAAAAAAAAAAAAAAAGAGTGCTAGGATTGGGCCAGTTAAGAGCAGGGGAGACCTGGCTGGGCATGGTGGCTCACACCTGTAATTCTAG
CACTTTGGGAGGCTGAGGCGGGTGGATCATGAGGTCAAGAGATTAAGACCATCCTGGCCTACATGGCGAAACCCTGTCTCTACTAAAAAT
AAAAAAATGACCTGGGCATGGTGGTGGGCGCCTGTAGTCCCAGCTACTCGGGGCGCTGAGGCAGGAGAATCGCTCGAACCCAGGAGGTGG
AGGTTGCAGTGAGCCGAGATTGCACAATTGCACTCCAGCCTGGCGACAGAGCGAGACTCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAG
GAGCAGGGGAGACCTATCAGTAGGGTGACCACGTGTCCTTTGCCTGGGCAGTCCAGGTTTATGCTTGTTTTCCAGTGAATTAGACCCCCT
TCCACTTTTCAAAAAAGTCCTGGTTTAGATGCTGTGATCACCAAACATATCAGGAAACAATATTCCTTGGTCTTGCTTCCCTATCTTCAG
GTACTGGTGGGCCAAATTCCTGGGACCAGGTCAAGGTGGGCTGCCTCAGTAAGAAGGAAGGACTGGAGAGTGCCCATTTCAGAGGAGCAG
GCTGGTGGGGGCCAGCCAGAAAGTAGTTCCCTTTGGGGGGAAGATGTTGGACCTTTATTATTTGTGGTAACCAGCCGAGGCTGGTTGTCA
GGACAGCAGGTGAGCCACTTTAGGGAAGAAAGTGCAGGGGTGGGTGGATGCCCAGATTACCAAGGCCAGCCACCCTGATGGGGTAGGGTC
TGGTTATCTGTGTTCAAGAAGCAAATCCCACCCCAGCCCCAGCACTAGCTCTCTATGTATGTATTTTCCCTGTACAATGTTTTATAAAAG
AGATCATTAATTTATCTGCTATGTTAAGGCTCGAGGGGTGGGGCGTAGACTCTCAGCTGTATATTGCTCTGGGGTGGGCAGGGAAGGCTG
AGTCTCACTTGACTTGGAAGATAAACAGGCCAGTTTGGACTGGCCTCCAGCTCCGTGGCTGTGTTTGTCTAACAAGGATTTGGGTAACTA
CTGGATACAAGCCACTGTGCTTAGTATGGATAGACTGCCATCAGCTCACCCACATGACTCCTGTTCATGGCAAGCTAATAGTCTGTCTGG
TGGAAGAGGATTGAAAAAGCACACAAAAACATCATAAATTACAAGGAGTAGTAAGAAGGAAAAAACAGGGAACGTGAGAGAATAACTAGC
GAGTGGGGAGAGGAGTGGATTTACTTTAACAGGGTAGTCAGGGAAGGCCTCTTGTGGTGGTGACATACTGATTTAGGCAAAGCGTCCAGC
ACGTGCCTAGCGCTTAGTAGTTGCTCAGCAAATGGCATCTTTGGGTGATGAATACCTCACATTTGTATATGGCCTGTCACAGTTTTCCAT

>74726_74726_3_RNF121-C6orf132_RNF121_chr11_71671937_ENST00000530137_C6orf132_chr6_42078029_ENST00000341865_length(amino acids)=1164AA_BP=135
MEVVLLGNGSWMRVEHARMHAKHRGHEAMHAEMVLILIATLVVAQLLLVQWKQRHPRSYNNAQENHGLAVPTPSVPDDFADKEVTGTSSL
VNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLS
SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEP
HLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQAD
ERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNEL
AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVR
QIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPK
ATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLP
TQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVE
RGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDA
EGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR
NNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRV

--------------------------------------------------------------
>74726_74726_4_RNF121-C6orf132_RNF121_chr11_71671937_ENST00000533380_C6orf132_chr6_42078029_ENST00000341865_length(transcript)=6193nt_BP=235nt
GGGACTGCGGTGAGGGGGCGAGCCGTGAAGATGGCGGCAGTGGTGGAGGTGGAGGTTGGAGGTGGTGCTGCTGGGGAACGGGAGCTGGAT
GAGGGTCGAGCACGCACGCATGCATGCCAAGCACCGTGGCCATGAAGCTATGCATGCTGAAATGGTCCTCATCCTCATCGCAACCTTGGT
GGTGGCCCAGCTGCTCCTGGTGCAGTGGAAGCAGAGGCACCCACGCTCCTACAATAATGCCCAGGAAAACCATGGGCTGGCTGTGCCCAC
CCCCTCGGTTCCAGATGATTTTGCAGACAAAGAAGTGACAGGTACCAGCTCACTAGTCAATGGCAACCTCCGACTGTACAGCTCTGTGGG
TGACCTGAGGCCTGGACAATATGGCCAGGATCTACTCATCCCCCCACCTCCCCCAGGCCCAGCCCCAGGGCCCCCTCAGGACATTTCAGA
ACCTCCAGGGGGGTCGCCACTGCCATCTCCACCTTCCACAGCACCCCCACCACCTCCCCTGCTGCTGGAACCCCCACCCCCGCCCAGCAT
GGCCCCACCTCCACCCCCAGTATTGGAGGCCCTATCCCCACCACACACTCTTTCCTCCCCATCCATACCCACCCCTCCTGACTTCATTCC
CCCTGCCCCACCCTTGGCCTTTCTAGCCCCCCCACCGCCTCCTGTGCCAGCCCCAGCACCCCCAGCTCCAGCATCTCCTCACACAGTGGG
GACTCGTCTCTTTCCCCCTGGGGGTGTCACCAAGTGGAAATCAGATGTAGCACTGAATGGCAGGCAGGCAGAGGCCACCAGAGCCAGCCC
CCCGAGAAGCCCTGCTGAGCCAAAGGGGAGCGCCCTGGGACCTAACCCAGAGCCCCATCTCACCTTCCCCCGTTCTTTCAAAGTGCCTCC
CCCAACCCCAGTCAGGACTTCGTCCATCCCAGTTCAGGAAGCACAAGAGGCTCCCCGAAAGGAAGAGGGGGCCACCAAGAAGGCTCCCAG
CCGACTCCCACTGCCTCCCAGCTTCCACATCCGCCCCGCCTCCCAGGTCTACCCAGACAGGGCCCCCGAGCCAGACTGCCCTGGGGAGCT
CAAGGCCACAGCACCAGCCAGCCCAAGGCTTGGCCAGTCCCAGTCCCAAGCAGATGAACGAGCTGGGACTCCGCCTCCAGCCCCTCCCCT
GCCCCCTCCTGCACCCCCCCTCCCTCCCCCAGCACCCCCACTTCCCCCAGCTGCACCTCCTTTGCCCTGTGCTCAGAAGGCAGCCCATCC
ACCTGCTGGGTTTACAAAAACCCCTAAATCCAGCTCTCCTGCTCTCAAACCCAAACCCAACCCCCCCAGCCCAGAGAACACAGCGTCTTC
AGCACCTGTGGACTGGAGGGACCCCAGCCAGATGGAAAAGCTGCGGAACGAGCTGGCAGCCTATCTCTGTGGCTCCAGGAGAGAGGACCG
ATTCCTCAGTCACAGGCCAGGCCCAACAGTGGCCCCTCAGAGCAAGGAGGGCAAGAAGGGCCCCCGCCTGCCTGAGAAGGAGACTCTCCT
GAGCCTGCCAGCAAAGGACACTCCCCCAGGTGTTCCTGAAAAGAGTCTTGGCGGCAGCAGCCTGACAGAGACAGAGGCTGCCCCCAGCCT
GACCCTGCCCTCTGTGGACTACATTCCCCAAGACTCTCCAACTCCCAGTGTGCGGCAGATCCGGAATGAGCTGGAGGCCCGGCTCTCCTC
AGCAGCAGAGAAGGAGGCTAAGCCCAGCATAGGATCTCTGCCCCCTAAGCCTCGGCTAGAAGGGGGAAGAATTTGTGAAAACGGGGCTGA
TGATGACAAACTCTCCAAGCCTGTGGCCAAGAATCTGCCACCTCAATCCACCACCCTGCTGCCAACTACATCACTCCAGCCCAAGGCTAT
GTTGGGACCAGCCATACCACCCAAGGCCACACCTGAGCCAGCCATACCACCCAAGGCTACACTTTGGCCAGCCACACCACCCAAGGCCAC
ACTTGGGCCAGCCACACCACTCAAGGCCACATCTGGGCCAACCACACCACTCAAGGCCACATCTGGCCCTGCCATAGCATCTACAGCCAC
AACTCTGCCCACCACCACATCCCAACTGATGGCAGAGAAGGACTCAGGCCCAGCTGGCCAGCCAGAGAAGCCAGCATCTCAAGAAGTTTC
CACTCCCTCCCAGGCAAGGGGAGAGGGGTCCCCCTCAGAGGCCACTAGGCTGCCCACACAGGGAGCCCGCTCATCTGCAGCCTTCCCACC
AAAGACATCTCCTGGTGGAGGAGAGGTGCCATGTCTCTACAAGCCCCACTGCCACCAGAGCAGCCTCAGCCGTGAGGTTGCTGTGGTGAT
GCCCACCCTGGCCAGAGGAGGGGCTGCAGGGCCAGGGGAGCCCGTGGAGGTGAAGGAGCCCCCAGGGCTGCCAGCCAAGCCTCCTGCCTC
GGCCCAGCCCACTGATGAACTCCTCAGGCACCCGGTGACTGGGGAGGTGGTGGAGCGGGGCTCGCCGATGGCCCTGCTCCTGGCGGCCAG
GCAGAGGGCTCAGAAGGGAAGGTCTGTAGGGGCTGCCCTGGGTCGGTCCTCTCTGCCAGGAAGTCTCCGTGACCACAGCCACCAAGCCGA
GGCCAGCTCTGACAGCATCTTCCACAGCCAGGGCACGCCCAACTCCTTCACTGTGGTGCCCAAGTTACCCAAGGAGGCTGAGAAGGACTC
CCCGCTGACGACCGAAATACCCAATAAGTGGGGGCCGCGGCTGGGAAGAGACGCAGAGGGCACAGAGCTGAGCCGCAGGCACAACTGGAC
AAAGCCAGAGCCCCAGGCCCCTGTGGCCTGGGAAAGAGTAGCTCCCTCCAACCTCCCCCAGGGCCACCCGCTGCCCAAGTCCTTCTCCTC
CCCACCTTCTCCTTCGAACAAGAGGGAGGAGGAGGAGGAGGAGTTCAACTTCGAGGTCATCCCACCGCCGCCAGAGTTCAGCAATGACCC
TGAGCCCCCGGCCCCGGCCCTCCAGTATCTGGGCCGCCAGAGCTCCCCTCCCCGGAACAACTACTCAGACTTGAGGCAGCTCCCGAACGC
TGGCCCCGGGGCGCCCCCGGCTCTCGGCTTCTCGCGCTTTCCCGCGGGCGCGCGCTACGCCGGGGCTGGGGGCCTGGAGCGCTTCTCGGG
AGGGGGCCGCTCGCTCATAAAGAAGCGCCTGTACGTCGGGGAGCCGCACCGAGGCCCAGGGCTACCCCACGGTGGCACCGGCCGCAGCCT
GAGCTCTCCCAACTGCTTCGGGCCGCAGCCCGGAGGCCCCGAGATGCGGCGCGTGAACTCGGCGGGTCGCGCGCCCCCCGGAGGCCTGCA
CGCGCCGAGGCTGTCCCTGGAGGGCGCCGCCCGGGGCGCCGCGGAGGCCAAGCACAAAGCGCCCGGCAGCGCCGACTACGGCTTCGCCCC
AGCTGCCGGCAGGTCTCCCTACACCACCACCCGCTATGGAAGCCCCATCAACACGTTCACCGTGAGGCCTGGGACCCGCCATCCCATCTC
CTATGTCTGCTCAGGGGCCCATCGGAAAGCCACCTCCTGAGCCAGGGGTTCTCTTAGCTCTACTCCAACAAACTGTGTCTTTAAGGATCT
GGGCACTTGTTTCTTGTGGGGGGTGGGAGGTACACAGCAGGTGTTGGGCGACCTGACTCAGACACAGAGGAGTCTTTGATCCCCAAAGAC
CAACGATGAGAAGCAGTGGCCCAGGAAGACCGAGAGTGGGCTTCTGTTTCCCAAAGCGCTGGTGTGACTGTGGACTGTTTACACGTGGGG
GGTGGGAGGGGAAGGAGGGTAGAGAGAAGGAACCATTAAGGACCTGGGCGCTGAGTTTCTGCTCTCTGGTACTATCTGCTTTAGCAAGAG
TTATTTAAAACAGTTTTACAAGCACGGCCTACTGAGCAGGTTCTGAAAGCAAGGGGTGGGGCACTGACTGAACTGGAACCCATCGAGATA
GCTGTGATTGCCTGTCAGGCCCTTGCAAAGGGCTGAGGCCCAGCTCTGTCTGGTGGGTGTGCAGGGCACCGAAGGGAGATCTTTAGCCTC
CATCACCTGCCATCCCAAGCAAGAGTGGACACCTGGGGTTCCTAGCCGCATTGAGGTGGGACCAGGAATGTGTATGTATAACATGTGGAG
AAGGACCATGTGTGGGGTGGGGAGTGAAGCTCCCACATGTGGAATGGAAGCCCTTTGCATTGGCCAAGGGCAGAGGTGGGAGATTGATGG
TTCATTTTTCCTTGGCCCTAGCCCTTAGCTACAGGGAGGCCTAGAGAGAGGACACTTGGCAAGTTTAGGATGGGAAACAAGGTTAAGCCT
GGCTTTGCTATTCAGACCTGTGCAGCCCTGATTTTGGGGACTGGGCCCAAGGAGCCATGAGTCTTAGGCTTGACACTAGGGGCCTTACAT
GGCCAGGTCTCATATGGGATTTGGAGAAGGCATTTTTCCTAACACTGATACTACAAGTCACCAATACTCTTGATGCCTTAAGATGCTAGA
AAGCCTTGGAGAGTGGAGGCAGCAGAGATGGGAATGGAGGTCTGAAGAAGCTTGCTGCTGTTGGGGAATGTGTTTGGGAAAGTCAAGAGT
GGTAGGATTGGTTGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCCGGTGGATCACTTGAGGTCAGAAG
TTCGAGACCAGCCTGCCCAAATGGTGAAACCCCATCTCTACTAAAAATACGGAAAAAAAAAAAAAAAGAGTGCTAGGATTGGGCCAGTTA
AGAGCAGGGGAGACCTGGCTGGGCATGGTGGCTCACACCTGTAATTCTAGCACTTTGGGAGGCTGAGGCGGGTGGATCATGAGGTCAAGA
GATTAAGACCATCCTGGCCTACATGGCGAAACCCTGTCTCTACTAAAAATAAAAAAATGACCTGGGCATGGTGGTGGGCGCCTGTAGTCC
CAGCTACTCGGGGCGCTGAGGCAGGAGAATCGCTCGAACCCAGGAGGTGGAGGTTGCAGTGAGCCGAGATTGCACAATTGCACTCCAGCC
TGGCGACAGAGCGAGACTCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAGGAGCAGGGGAGACCTATCAGTAGGGTGACCACGTGTCCTT
TGCCTGGGCAGTCCAGGTTTATGCTTGTTTTCCAGTGAATTAGACCCCCTTCCACTTTTCAAAAAAGTCCTGGTTTAGATGCTGTGATCA
CCAAACATATCAGGAAACAATATTCCTTGGTCTTGCTTCCCTATCTTCAGGTACTGGTGGGCCAAATTCCTGGGACCAGGTCAAGGTGGG
CTGCCTCAGTAAGAAGGAAGGACTGGAGAGTGCCCATTTCAGAGGAGCAGGCTGGTGGGGGCCAGCCAGAAAGTAGTTCCCTTTGGGGGG
AAGATGTTGGACCTTTATTATTTGTGGTAACCAGCCGAGGCTGGTTGTCAGGACAGCAGGTGAGCCACTTTAGGGAAGAAAGTGCAGGGG
TGGGTGGATGCCCAGATTACCAAGGCCAGCCACCCTGATGGGGTAGGGTCTGGTTATCTGTGTTCAAGAAGCAAATCCCACCCCAGCCCC
AGCACTAGCTCTCTATGTATGTATTTTCCCTGTACAATGTTTTATAAAAGAGATCATTAATTTATCTGCTATGTTAAGGCTCGAGGGGTG
GGGCGTAGACTCTCAGCTGTATATTGCTCTGGGGTGGGCAGGGAAGGCTGAGTCTCACTTGACTTGGAAGATAAACAGGCCAGTTTGGAC
TGGCCTCCAGCTCCGTGGCTGTGTTTGTCTAACAAGGATTTGGGTAACTACTGGATACAAGCCACTGTGCTTAGTATGGATAGACTGCCA
TCAGCTCACCCACATGACTCCTGTTCATGGCAAGCTAATAGTCTGTCTGGTGGAAGAGGATTGAAAAAGCACACAAAAACATCATAAATT
ACAAGGAGTAGTAAGAAGGAAAAAACAGGGAACGTGAGAGAATAACTAGCGAGTGGGGAGAGGAGTGGATTTACTTTAACAGGGTAGTCA
GGGAAGGCCTCTTGTGGTGGTGACATACTGATTTAGGCAAAGCGTCCAGCACGTGCCTAGCGCTTAGTAGTTGCTCAGCAAATGGCATCT

>74726_74726_4_RNF121-C6orf132_RNF121_chr11_71671937_ENST00000533380_C6orf132_chr6_42078029_ENST00000341865_length(amino acids)=1164AA_BP=135
MEVVLLGNGSWMRVEHARMHAKHRGHEAMHAEMVLILIATLVVAQLLLVQWKQRHPRSYNNAQENHGLAVPTPSVPDDFADKEVTGTSSL
VNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLS
SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEP
HLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQAD
ERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNEL
AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVR
QIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPK
ATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLP
TQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVE
RGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDA
EGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR
NNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRV

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Fusion Gene PPI Analysis for RNF121-C6orf132


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RNF121-C6orf132


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RNF121-C6orf132


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource