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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RNF139-ASPH (FusionGDB2 ID:74787)

Fusion Gene Summary for RNF139-ASPH

check button Fusion gene summary
Fusion gene informationFusion gene name: RNF139-ASPH
Fusion gene ID: 74787
HgeneTgene
Gene symbol

RNF139

ASPH

Gene ID

11236

444

Gene namering finger protein 139aspartate beta-hydroxylase
SynonymsHRCA1|RCA1|TRC8AAH|BAH|CASQ2BP1|FDLAB|HAAH|JCTN|junctin
Cytomap

8q24.13

8q12.3

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase RNF139RING-type E3 ubiquitin transferase RNF139multiple membrane spanning receptor TRC8patched related protein translocated in renal cancertranslocation in renal carcinoma on chromosome 8 proteintranslocation in renal carcaspartyl/asparaginyl beta-hydroxylaseA beta H-J-JASP beta-hydroxylasecardiac junctinhumbugjunctatepeptide-aspartate beta-dioxygenase
Modification date2020031320200315
UniProtAcc.

Q6ICH7

Ensembl transtripts involved in fusion geneENST00000303545, ENST00000356457, 
ENST00000379449, ENST00000389204, 
ENST00000445642, ENST00000517661, 
ENST00000517847, ENST00000517856, 
ENST00000517903, ENST00000518068, 
ENST00000522603, ENST00000522835, 
ENST00000522919, ENST00000523897, 
ENST00000379454, ENST00000541428, 
Fusion gene scores* DoF score6 X 3 X 5=9017 X 17 X 5=1445
# samples 619
** MAII scorelog2(6/90*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/1445*10)=-2.92699816905709
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RNF139 [Title/Abstract] AND ASPH [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRNF139(125487531)-ASPH(62566219), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRNF139

GO:0008285

negative regulation of cell proliferation

17016439

HgeneRNF139

GO:0016567

protein ubiquitination

10500182|17016439

HgeneRNF139

GO:0017148

negative regulation of translation

20068067

HgeneRNF139

GO:0060628

regulation of ER to Golgi vesicle-mediated transport

19706601

HgeneRNF139

GO:0070613

regulation of protein processing

19706601

TgeneASPH

GO:0045862

positive regulation of proteolysis

18387192

TgeneASPH

GO:0097202

activation of cysteine-type endopeptidase activity

18387192


check buttonFusion gene breakpoints across RNF139 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ASPH (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AN-A041-01ARNF139chr8

125487531

+ASPHchr8

62566219

-


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Fusion Gene ORF analysis for RNF139-ASPH

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000303545ENST00000356457RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000379449RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000389204RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000445642RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000517661RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000517847RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000517856RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000517903RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000518068RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000522603RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000522835RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000522919RNF139chr8

125487531

+ASPHchr8

62566219

-
5CDS-intronENST00000303545ENST00000523897RNF139chr8

125487531

+ASPHchr8

62566219

-
In-frameENST00000303545ENST00000379454RNF139chr8

125487531

+ASPHchr8

62566219

-
In-frameENST00000303545ENST00000541428RNF139chr8

125487531

+ASPHchr8

62566219

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000303545RNF139chr8125487531+ENST00000541428ASPHchr862566219-53105531862507773
ENST00000303545RNF139chr8125487531+ENST00000379454ASPHchr862566219-46385531862507773

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000303545ENST00000541428RNF139chr8125487531+ASPHchr862566219-0.0003382210.9996618
ENST00000303545ENST00000379454RNF139chr8125487531+ASPHchr862566219-0.0008859430.9991141

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Fusion Genomic Features for RNF139-ASPH


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RNF139-ASPH


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:125487531/chr8:62566219)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ASPH

Q6ICH7

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May function as 2-oxoglutarate-dependent dioxygenase. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneASPHchr8:125487531chr8:62566219ENST000003794490590_1020204.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:125487531chr8:62566219ENST000003892040690_1020226.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:125487531chr8:62566219ENST000005226030590_1020211.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:125487531chr8:62566219ENST0000054142822590_10278730.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:125487531chr8:62566219ENST00000356457214111_312107314.0Compositional biasNote=Glu-rich
TgeneASPHchr8:125487531chr8:62566219ENST00000356457214323_332107314.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:125487531chr8:62566219ENST0000037944905111_3120204.0Compositional biasNote=Glu-rich
TgeneASPHchr8:125487531chr8:62566219ENST0000037944905323_3320204.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:125487531chr8:62566219ENST00000379449059_290204.0Compositional biasNote=Ser-rich
TgeneASPHchr8:125487531chr8:62566219ENST00000379454225111_312107759.0Compositional biasNote=Glu-rich
TgeneASPHchr8:125487531chr8:62566219ENST00000379454225323_332107759.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:125487531chr8:62566219ENST0000038920406111_3120226.0Compositional biasNote=Glu-rich
TgeneASPHchr8:125487531chr8:62566219ENST0000038920406323_3320226.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:125487531chr8:62566219ENST00000389204069_290226.0Compositional biasNote=Ser-rich
TgeneASPHchr8:125487531chr8:62566219ENST00000445642316111_31293651.6666666666666Compositional biasNote=Glu-rich
TgeneASPHchr8:125487531chr8:62566219ENST00000445642316323_33293651.6666666666666Compositional biasNote=Poly-Lys
TgeneASPHchr8:125487531chr8:62566219ENST00000517847315111_31293300.0Compositional biasNote=Glu-rich
TgeneASPHchr8:125487531chr8:62566219ENST00000517847315323_33293300.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:125487531chr8:62566219ENST00000517903315111_31293299.0Compositional biasNote=Glu-rich
TgeneASPHchr8:125487531chr8:62566219ENST00000517903315323_33293299.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:125487531chr8:62566219ENST00000518068213111_312107271.0Compositional biasNote=Glu-rich
TgeneASPHchr8:125487531chr8:62566219ENST00000518068213323_332107271.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:125487531chr8:62566219ENST0000052260305111_3120211.0Compositional biasNote=Glu-rich
TgeneASPHchr8:125487531chr8:62566219ENST0000052260305323_3320211.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:125487531chr8:62566219ENST00000522603059_290211.0Compositional biasNote=Ser-rich
TgeneASPHchr8:125487531chr8:62566219ENST00000522835314111_31293257.0Compositional biasNote=Glu-rich
TgeneASPHchr8:125487531chr8:62566219ENST00000522835314323_33293257.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:125487531chr8:62566219ENST00000541428225111_31278730.0Compositional biasNote=Glu-rich
TgeneASPHchr8:125487531chr8:62566219ENST00000541428225323_33278730.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:125487531chr8:62566219ENST00000356457214688_690107314.0Region2-oxoglutarate binding
TgeneASPHchr8:125487531chr8:62566219ENST0000037944905688_6900204.0Region2-oxoglutarate binding
TgeneASPHchr8:125487531chr8:62566219ENST00000379454225688_690107759.0Region2-oxoglutarate binding
TgeneASPHchr8:125487531chr8:62566219ENST0000038920406688_6900226.0Region2-oxoglutarate binding
TgeneASPHchr8:125487531chr8:62566219ENST00000445642316688_69093651.6666666666666Region2-oxoglutarate binding
TgeneASPHchr8:125487531chr8:62566219ENST00000517847315688_69093300.0Region2-oxoglutarate binding
TgeneASPHchr8:125487531chr8:62566219ENST00000517903315688_69093299.0Region2-oxoglutarate binding
TgeneASPHchr8:125487531chr8:62566219ENST00000518068213688_690107271.0Region2-oxoglutarate binding
TgeneASPHchr8:125487531chr8:62566219ENST0000052260305688_6900211.0Region2-oxoglutarate binding
TgeneASPHchr8:125487531chr8:62566219ENST00000522835314688_69093257.0Region2-oxoglutarate binding
TgeneASPHchr8:125487531chr8:62566219ENST00000541428225688_69078730.0Region2-oxoglutarate binding
TgeneASPHchr8:125487531chr8:62566219ENST00000356457214341_374107314.0RepeatNote=TPR 1
TgeneASPHchr8:125487531chr8:62566219ENST00000356457214454_487107314.0RepeatNote=TPR 2
TgeneASPHchr8:125487531chr8:62566219ENST00000356457214489_521107314.0RepeatNote=TPR 3
TgeneASPHchr8:125487531chr8:62566219ENST00000356457214525_557107314.0RepeatNote=TPR 4
TgeneASPHchr8:125487531chr8:62566219ENST0000037944905341_3740204.0RepeatNote=TPR 1
TgeneASPHchr8:125487531chr8:62566219ENST0000037944905454_4870204.0RepeatNote=TPR 2
TgeneASPHchr8:125487531chr8:62566219ENST0000037944905489_5210204.0RepeatNote=TPR 3
TgeneASPHchr8:125487531chr8:62566219ENST0000037944905525_5570204.0RepeatNote=TPR 4
TgeneASPHchr8:125487531chr8:62566219ENST00000379454225341_374107759.0RepeatNote=TPR 1
TgeneASPHchr8:125487531chr8:62566219ENST00000379454225454_487107759.0RepeatNote=TPR 2
TgeneASPHchr8:125487531chr8:62566219ENST00000379454225489_521107759.0RepeatNote=TPR 3
TgeneASPHchr8:125487531chr8:62566219ENST00000379454225525_557107759.0RepeatNote=TPR 4
TgeneASPHchr8:125487531chr8:62566219ENST0000038920406341_3740226.0RepeatNote=TPR 1
TgeneASPHchr8:125487531chr8:62566219ENST0000038920406454_4870226.0RepeatNote=TPR 2
TgeneASPHchr8:125487531chr8:62566219ENST0000038920406489_5210226.0RepeatNote=TPR 3
TgeneASPHchr8:125487531chr8:62566219ENST0000038920406525_5570226.0RepeatNote=TPR 4
TgeneASPHchr8:125487531chr8:62566219ENST00000445642316341_37493651.6666666666666RepeatNote=TPR 1
TgeneASPHchr8:125487531chr8:62566219ENST00000445642316454_48793651.6666666666666RepeatNote=TPR 2
TgeneASPHchr8:125487531chr8:62566219ENST00000445642316489_52193651.6666666666666RepeatNote=TPR 3
TgeneASPHchr8:125487531chr8:62566219ENST00000445642316525_55793651.6666666666666RepeatNote=TPR 4
TgeneASPHchr8:125487531chr8:62566219ENST00000517847315341_37493300.0RepeatNote=TPR 1
TgeneASPHchr8:125487531chr8:62566219ENST00000517847315454_48793300.0RepeatNote=TPR 2
TgeneASPHchr8:125487531chr8:62566219ENST00000517847315489_52193300.0RepeatNote=TPR 3
TgeneASPHchr8:125487531chr8:62566219ENST00000517847315525_55793300.0RepeatNote=TPR 4
TgeneASPHchr8:125487531chr8:62566219ENST00000517903315341_37493299.0RepeatNote=TPR 1
TgeneASPHchr8:125487531chr8:62566219ENST00000517903315454_48793299.0RepeatNote=TPR 2
TgeneASPHchr8:125487531chr8:62566219ENST00000517903315489_52193299.0RepeatNote=TPR 3
TgeneASPHchr8:125487531chr8:62566219ENST00000517903315525_55793299.0RepeatNote=TPR 4
TgeneASPHchr8:125487531chr8:62566219ENST00000518068213341_374107271.0RepeatNote=TPR 1
TgeneASPHchr8:125487531chr8:62566219ENST00000518068213454_487107271.0RepeatNote=TPR 2
TgeneASPHchr8:125487531chr8:62566219ENST00000518068213489_521107271.0RepeatNote=TPR 3
TgeneASPHchr8:125487531chr8:62566219ENST00000518068213525_557107271.0RepeatNote=TPR 4
TgeneASPHchr8:125487531chr8:62566219ENST0000052260305341_3740211.0RepeatNote=TPR 1
TgeneASPHchr8:125487531chr8:62566219ENST0000052260305454_4870211.0RepeatNote=TPR 2
TgeneASPHchr8:125487531chr8:62566219ENST0000052260305489_5210211.0RepeatNote=TPR 3
TgeneASPHchr8:125487531chr8:62566219ENST0000052260305525_5570211.0RepeatNote=TPR 4
TgeneASPHchr8:125487531chr8:62566219ENST00000522835314341_37493257.0RepeatNote=TPR 1
TgeneASPHchr8:125487531chr8:62566219ENST00000522835314454_48793257.0RepeatNote=TPR 2
TgeneASPHchr8:125487531chr8:62566219ENST00000522835314489_52193257.0RepeatNote=TPR 3
TgeneASPHchr8:125487531chr8:62566219ENST00000522835314525_55793257.0RepeatNote=TPR 4
TgeneASPHchr8:125487531chr8:62566219ENST00000541428225341_37478730.0RepeatNote=TPR 1
TgeneASPHchr8:125487531chr8:62566219ENST00000541428225454_48778730.0RepeatNote=TPR 2
TgeneASPHchr8:125487531chr8:62566219ENST00000541428225489_52178730.0RepeatNote=TPR 3
TgeneASPHchr8:125487531chr8:62566219ENST00000541428225525_55778730.0RepeatNote=TPR 4
TgeneASPHchr8:125487531chr8:62566219ENST00000379449051_530204.0Topological domainCytoplasmic
TgeneASPHchr8:125487531chr8:62566219ENST000003794490575_7580204.0Topological domainLumenal
TgeneASPHchr8:125487531chr8:62566219ENST00000389204061_530226.0Topological domainCytoplasmic
TgeneASPHchr8:125487531chr8:62566219ENST000003892040675_7580226.0Topological domainLumenal
TgeneASPHchr8:125487531chr8:62566219ENST00000522603051_530211.0Topological domainCytoplasmic
TgeneASPHchr8:125487531chr8:62566219ENST000005226030575_7580211.0Topological domainLumenal
TgeneASPHchr8:125487531chr8:62566219ENST000003794490554_740204.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:125487531chr8:62566219ENST000003892040654_740226.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:125487531chr8:62566219ENST000005226030554_740211.0TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+12125_14560665.0TransmembraneHelical
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+12154_17460665.0TransmembraneHelical
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+12178_19860665.0TransmembraneHelical
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+12293_31360665.0TransmembraneHelical
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+12323_34360665.0TransmembraneHelical
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+12356_37660665.0TransmembraneHelical
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+12390_41060665.0TransmembraneHelical
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+12420_44060665.0TransmembraneHelical
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+12469_48960665.0TransmembraneHelical
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+12495_51260665.0TransmembraneHelical
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+1251_7160665.0TransmembraneHelical
HgeneRNF139chr8:125487531chr8:62566219ENST00000303545+1285_10560665.0TransmembraneHelical
TgeneASPHchr8:125487531chr8:62566219ENST0000035645721490_102107314.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:125487531chr8:62566219ENST0000037945422590_102107759.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:125487531chr8:62566219ENST0000044564231690_10293651.6666666666666Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:125487531chr8:62566219ENST0000051784731590_10293300.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:125487531chr8:62566219ENST0000051790331590_10293299.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:125487531chr8:62566219ENST0000051806821390_102107271.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:125487531chr8:62566219ENST0000052283531490_10293257.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:125487531chr8:62566219ENST000003564572149_29107314.0Compositional biasNote=Ser-rich
TgeneASPHchr8:125487531chr8:62566219ENST000003794542259_29107759.0Compositional biasNote=Ser-rich
TgeneASPHchr8:125487531chr8:62566219ENST000004456423169_2993651.6666666666666Compositional biasNote=Ser-rich
TgeneASPHchr8:125487531chr8:62566219ENST000005178473159_2993300.0Compositional biasNote=Ser-rich
TgeneASPHchr8:125487531chr8:62566219ENST000005179033159_2993299.0Compositional biasNote=Ser-rich
TgeneASPHchr8:125487531chr8:62566219ENST000005180682139_29107271.0Compositional biasNote=Ser-rich
TgeneASPHchr8:125487531chr8:62566219ENST000005228353149_2993257.0Compositional biasNote=Ser-rich
TgeneASPHchr8:125487531chr8:62566219ENST000005414282259_2978730.0Compositional biasNote=Ser-rich
TgeneASPHchr8:125487531chr8:62566219ENST000003564572141_53107314.0Topological domainCytoplasmic
TgeneASPHchr8:125487531chr8:62566219ENST0000035645721475_758107314.0Topological domainLumenal
TgeneASPHchr8:125487531chr8:62566219ENST000003794542251_53107759.0Topological domainCytoplasmic
TgeneASPHchr8:125487531chr8:62566219ENST0000037945422575_758107759.0Topological domainLumenal
TgeneASPHchr8:125487531chr8:62566219ENST000004456423161_5393651.6666666666666Topological domainCytoplasmic
TgeneASPHchr8:125487531chr8:62566219ENST0000044564231675_75893651.6666666666666Topological domainLumenal
TgeneASPHchr8:125487531chr8:62566219ENST000005178473151_5393300.0Topological domainCytoplasmic
TgeneASPHchr8:125487531chr8:62566219ENST0000051784731575_75893300.0Topological domainLumenal
TgeneASPHchr8:125487531chr8:62566219ENST000005179033151_5393299.0Topological domainCytoplasmic
TgeneASPHchr8:125487531chr8:62566219ENST0000051790331575_75893299.0Topological domainLumenal
TgeneASPHchr8:125487531chr8:62566219ENST000005180682131_53107271.0Topological domainCytoplasmic
TgeneASPHchr8:125487531chr8:62566219ENST0000051806821375_758107271.0Topological domainLumenal
TgeneASPHchr8:125487531chr8:62566219ENST000005228353141_5393257.0Topological domainCytoplasmic
TgeneASPHchr8:125487531chr8:62566219ENST0000052283531475_75893257.0Topological domainLumenal
TgeneASPHchr8:125487531chr8:62566219ENST000005414282251_5378730.0Topological domainCytoplasmic
TgeneASPHchr8:125487531chr8:62566219ENST0000054142822575_75878730.0Topological domainLumenal
TgeneASPHchr8:125487531chr8:62566219ENST0000035645721454_74107314.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:125487531chr8:62566219ENST0000037945422554_74107759.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:125487531chr8:62566219ENST0000044564231654_7493651.6666666666666TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:125487531chr8:62566219ENST0000051784731554_7493300.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:125487531chr8:62566219ENST0000051790331554_7493299.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:125487531chr8:62566219ENST0000051806821354_74107271.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:125487531chr8:62566219ENST0000052283531454_7493257.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:125487531chr8:62566219ENST0000054142822554_7478730.0TransmembraneHelical%3B Signal-anchor for type II membrane protein


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Fusion Gene Sequence for RNF139-ASPH


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>74787_74787_1_RNF139-ASPH_RNF139_chr8_125487531_ENST00000303545_ASPH_chr8_62566219_ENST00000379454_length(transcript)=4638nt_BP=553nt
GACTGACGGCGCAGCCTCCGGGCCTAGCCACAGCAGCAACGGCAGAGGCCAGCGGGCGAGGTCAAGATGGTGGCTCCGCGGGCGGGGGAG
GCAGTGGAGGGAGGAGGAGTCAGACCTTAGCCAGCCGGAAACACCGAAACCCAGAGACCTCCTGGGGAGCCGCCGCCGCCGCCCTCTCGG
CCATCGCTGCCTCCGCCGCCTGCTCCACCTCGAGGGACGCGAGCGGGCGGCGGGGCTGGCCGTGAGAGAGACAGGAGAGGAAGGAGGGCA
GGGGCGGAGTTGCCCGCCTTAGCCCCCGCCCCCGGCCGCGGCCCCGGGCCCTGCCCCGCGCGGCCCTGCCCGGCCCACCGAGCCCTGGTG
TGGCAGCGGCTCATGGCGGCCGTGGGGCCCCCGCAGCAGCAGGTGCGGATGGCCCATCAGCAGGTCTGGGCGGCGCTCGAAGTGGCGCTC
CGGGTGCCCTGCCTTTACATCATCGACGCCATCTTCAACTCCTACCCGGATTCCAGCCAAAGCCGGTTCTGCATCGTGCTCCAGATCTTC
CTCCGGCTCTTTGGACTTAAAGAGAGATCTACTTCAGAGCCAGCAGTCCCGCCAGAAGAGGCTGAGCCACACACTGAGCCCGAGGAGCAG
GTTCCTGTGGAGGCAGAACCCCAGAATATCGAAGATGAAGCAAAAGAACAAATTCAGTCCCTTCTCCATGAAATGGTACACGCAGAACAT
GTTGAGGGAGAAGACTTGCAACAAGAAGATGGACCCACAGGAGAACCACAACAAGAGGATGATGAGTTTCTTATGGCGACTGATGTAGAT
GATAGATTTGAGACCCTGGAACCTGAAGTATCTCATGAAGAAACCGAGCATAGTTACCACGTGGAAGAGACAGTTTCACAAGACTGTAAT
CAGGATATGGAAGAGATGATGTCTGAGCAGGAAAATCCAGATTCCAGTGAACCAGTAGTAGAAGATGAAAGATTGCACCATGATACAGAT
GATGTAACATACCAAGTCTATGAGGAACAAGCAGTATATGAACCTCTAGAAAATGAAGGGATAGAAATCACAGAAGTAACTGCTCCCCCT
GAGGATAATCCTGTAGAAGATTCACAGGTAATTGTAGAAGAAGTAAGCATTTTTCCTGTGGAAGAACAGCAGGAAGTACCACCAGAAACA
AATAGAAAAACAGATGATCCAGAACAAAAAGCAAAAGTTAAGAAAAAGAAGCCTAAACTTTTAAATAAATTTGATAAGACTATTAAAGCT
GAACTTGATGCTGCAGAAAAACTCCGTAAAAGGGGAAAAATTGAGGAAGCAGTGAATGCATTTAAAGAACTAGTACGCAAATACCCTCAG
AGTCCACGAGCAAGATATGGGAAGGCGCAGTGTGAGGATGATTTGGCTGAGAAGAGGAGAAGTAATGAGGTGCTACGTGGAGCCATCGAG
ACCTACCAAGAGGTGGCCAGCCTACCTGATGTCCCTGCAGACCTGCTGAAGCTGAGTTTGAAGCGTCGCTCAGACAGGCAACAATTTCTA
GGTCATATGAGAGGTTCCCTGCTTACCCTGCAGAGATTAGTTCAACTATTTCCCAATGATACTTCCTTAAAAAATGACCTTGGCGTGGGA
TACCTCTTGATAGGAGATAATGACAATGCAAAGAAAGTTTATGAAGAGGTGCTGAGTGTGACACCTAATGATGGCTTTGCTAAAGTCCAT
TATGGCTTCATCCTGAAGGCACAGAACAAAATTGCTGAGAGCATCCCATATTTAAAGGAAGGAATAGAATCCGGAGATCCTGGCACTGAT
GATGGGAGATTTTATTTCCACCTGGGGGATGCCATGCAGAGGGTTGGGAACAAAGAGGCATATAAGTGGTATGAGCTTGGGCACAAGAGA
GGACACTTTGCATCTGTCTGGCAACGCTCACTCTACAATGTGAATGGACTGAAAGCACAGCCTTGGTGGACCCCAAAAGAAACGGGCTAC
ACAGAGTTAGTAAAGTCTTTAGAAAGAAACTGGAAGTTAATCCGAGATGAAGGCCTTGCAGTGATGGATAAAGCCAAAGGTCTCTTCCTG
CCTGAGGATGAAAACCTGAGGGAAAAAGGGGACTGGAGCCAGTTCACGCTGTGGCAGCAAGGAAGAAGAAATGAAAATGCCTGCAAAGGA
GCTCCTAAAACCTGTACCTTACTAGAAAAGTTCCCCGAGACAACAGGATGCAGAAGAGGACAGATCAAATATTCCATCATGCACCCCGGG
ACTCACGTGTGGCCGCACACAGGGCCCACAAACTGCAGGCTCCGAATGCACCTGGGCTTGGTGATTCCCAAGGAAGGCTGCAAGATTCGA
TGTGCCAACGAGACCAAGACCTGGGAGGAAGGCAAGGTGCTCATCTTTGATGACTCCTTTGAGCACGAGGTATGGCAGGATGCCTCATCT
TTCCGGCTGATATTCATCGTGGATGTGTGGCATCCGGAACTGACACCACAGCAGAGACGCAGCCTTCCAGCAATTTAGCATGAATTCATG
CAAGCTTGGGAAACTCTGGAGAGAGGCTGCCTTTCTGGTTCCATCTCCTTGGGTGTGAGGATAGAATTTCGAACACCAAGAGTCAATTCC
CTTGACTTGCAGCCCGAGTAATTCAAAGCCTCCTCCTAGGGTCAGAAGACACTAAAGGGAATATTTGCCTCGCTGCAATTCATTTAGGAA
ACACCCTGCTGTGTGTCATCTCATGACAGCACTGGTCTTCTGCCAGTATTTAAGGTGAACATTTGATAGCTTCTACCTTACCAGCCAAAG
ATATTTTTTCCACATAGAATAGGTCTAATTCAATGTATAATGAGAACATATGTAGAAACTGTGAATGGATTGCTTTAGTTTGTAATTTTT
CTATGCAGTTATATTTTTCTAGTGTAGCTAGACTATTTTGTCATCATGTACCACTACATTTTTGTTTATTTTAATGACAAGCTGTATAAA
TGCTTTACTTCTAGCTATTTAATGGTAGCATTACTGGGGAACTCAGACTTCCCTCTTTTAATTCTTCTTAGTAAAAGATACTCATGAAAA
AAGCAGTTTTATTTTCCTAACAAAAAAGAAAGAGCTCATTATGTCAGTGTCTATGAACTGTACCCATCCCAACTCTCAAATCGTTTGGTT
TTTTTTATCTTGATTGAGATCCTCTTCTCACTATGCTAGTGGTGGAGATATTGACAAAATCCTATTTCTTTCAAAGAGGAACTTTTCACA
CCGAAAAAAGAGCATGGAATTATTTTATATTGTTATAAAAATCCCAGATGCAAATTTTTTTAATGCCAATTATTAGAGCTTCTGGGGAAA
AAGTATAGTTCACGGAAATAAAACTATGTTCTTTCAGGGTTGGGTGGATAGGTGGCTGCTAGGGTGTCTGGCTCCTGGCGGCTTTGCCAT
CCATGAGGCAAGGGCTGGGAACACAGTGTCTTTGCCTATGGTAGATCCATGTGAATGTCAGGAAGCCAGCTCTTCAGTCTTGGAGATGAT
TTCTGCTACAATTCTGTAGAAAGATTAAGGATGGCAGAGTAAAAGGTTACCAAGAATGCCAGGATGTTTTTCTTGGGCGTAGGAGGTCCA
GATTACTTTCCTTTTTGATGAAAGAGTTTGGAAGACTGTCCCATCTCTCTGGCTTGAGAAATCTCTGCCATTTTAAACATCACTGTGAAA
TAGCAATTATTATCATCTGTATTTAGTTTTAACATTACCCACAACATAGAAATAATAGGTAAAAATCGTCTTGCCTACTCATTCCAAAGA
TGATCAAGTCATTAATCTAGCAAAGTATTCATGTATCAGATTTTGTATATTTTGAATCAAAGCTAACTAGGAATGTTAGATATAAGAATG
TAATGATATTCATGCACTGAATTCTAAGCCAATATGAACAAAAATGCTGCATGAATGGCACATATAGGTCACCAAAGTTCATTCACAGGT
AGAAAAAACTTGTGCTTTCTTTTCCATCTAAAAACAAAAGGAGACTTTCTTTATCTCATTTAAAGAACAGCTCTTTGAAATTGAAATTGA
CCCTTTTTGCTTGACCTTAAGGAGATTAGCTTCCAGTAGATGAGTTTGCAAAATACTTTTCCTGTTCTTTTGTTTTGCTGGTATTGAAAA
CATCCCACTAAATCAGATGAAGAGGCATGGGAGGAAAAATATCCAAATTAATTACTAAAATCGAGAAGAGAAGGCAAACTCTTGAAAAGT
AAAAAGGTGTTTGTGACCTTCAGTATTTATTGAACAGAGGAAATAACTGACAAGGGCAATACAATTCAATGTTCATGTAGTAACATTCAT
GTCACTTGTTGAATTTGGTTCTCATATGTATATTGCATACACATAAATTCAAACTATAAGTCGTCATTTTTGAGCCATCATCTTACATTC
ATGTAATGAAATTATGGAAGAGAGTAAAAACTAGCTCTTAACTTAGTAAATATAATATGGTATTTAAAATCAGGTCACTACAGTAAGGTT
CTAAGTATTGCCAATTGAAAAGCTAGAAATGGTATTACTGTTGCAAAGTGTTGTCAATAATTGACTCCAATAGCATTGTAAATACTTGTA

>74787_74787_1_RNF139-ASPH_RNF139_chr8_125487531_ENST00000303545_ASPH_chr8_62566219_ENST00000379454_length(amino acids)=773AA_BP=122
MPPPPAPPRGTRAGGGAGRERDRRGRRAGAELPALAPAPGRGPGPCPARPCPAHRALVWQRLMAAVGPPQQQVRMAHQQVWAALEVALRV
PCLYIIDAIFNSYPDSSQSRFCIVLQIFLRLFGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVE
GEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDV
TYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAEL
DAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVASLPDVPADLLKLSLKRRSDRQQFLGH
MRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKVYEEVLSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDDG
RFYFHLGDAMQRVGNKEAYKWYELGHKRGHFASVWQRSLYNVNGLKAQPWWTPKETGYTELVKSLERNWKLIRDEGLAVMDKAKGLFLPE
DENLREKGDWSQFTLWQQGRRNENACKGAPKTCTLLEKFPETTGCRRGQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCA

--------------------------------------------------------------
>74787_74787_2_RNF139-ASPH_RNF139_chr8_125487531_ENST00000303545_ASPH_chr8_62566219_ENST00000541428_length(transcript)=5310nt_BP=553nt
GACTGACGGCGCAGCCTCCGGGCCTAGCCACAGCAGCAACGGCAGAGGCCAGCGGGCGAGGTCAAGATGGTGGCTCCGCGGGCGGGGGAG
GCAGTGGAGGGAGGAGGAGTCAGACCTTAGCCAGCCGGAAACACCGAAACCCAGAGACCTCCTGGGGAGCCGCCGCCGCCGCCCTCTCGG
CCATCGCTGCCTCCGCCGCCTGCTCCACCTCGAGGGACGCGAGCGGGCGGCGGGGCTGGCCGTGAGAGAGACAGGAGAGGAAGGAGGGCA
GGGGCGGAGTTGCCCGCCTTAGCCCCCGCCCCCGGCCGCGGCCCCGGGCCCTGCCCCGCGCGGCCCTGCCCGGCCCACCGAGCCCTGGTG
TGGCAGCGGCTCATGGCGGCCGTGGGGCCCCCGCAGCAGCAGGTGCGGATGGCCCATCAGCAGGTCTGGGCGGCGCTCGAAGTGGCGCTC
CGGGTGCCCTGCCTTTACATCATCGACGCCATCTTCAACTCCTACCCGGATTCCAGCCAAAGCCGGTTCTGCATCGTGCTCCAGATCTTC
CTCCGGCTCTTTGGACTTAAAGAGAGATCTACTTCAGAGCCAGCAGTCCCGCCAGAAGAGGCTGAGCCACACACTGAGCCCGAGGAGCAG
GTTCCTGTGGAGGCAGAACCCCAGAATATCGAAGATGAAGCAAAAGAACAAATTCAGTCCCTTCTCCATGAAATGGTACACGCAGAACAT
GTTGAGGGAGAAGACTTGCAACAAGAAGATGGACCCACAGGAGAACCACAACAAGAGGATGATGAGTTTCTTATGGCGACTGATGTAGAT
GATAGATTTGAGACCCTGGAACCTGAAGTATCTCATGAAGAAACCGAGCATAGTTACCACGTGGAAGAGACAGTTTCACAAGACTGTAAT
CAGGATATGGAAGAGATGATGTCTGAGCAGGAAAATCCAGATTCCAGTGAACCAGTAGTAGAAGATGAAAGATTGCACCATGATACAGAT
GATGTAACATACCAAGTCTATGAGGAACAAGCAGTATATGAACCTCTAGAAAATGAAGGGATAGAAATCACAGAAGTAACTGCTCCCCCT
GAGGATAATCCTGTAGAAGATTCACAGGTAATTGTAGAAGAAGTAAGCATTTTTCCTGTGGAAGAACAGCAGGAAGTACCACCAGAAACA
AATAGAAAAACAGATGATCCAGAACAAAAAGCAAAAGTTAAGAAAAAGAAGCCTAAACTTTTAAATAAATTTGATAAGACTATTAAAGCT
GAACTTGATGCTGCAGAAAAACTCCGTAAAAGGGGAAAAATTGAGGAAGCAGTGAATGCATTTAAAGAACTAGTACGCAAATACCCTCAG
AGTCCACGAGCAAGATATGGGAAGGCGCAGTGTGAGGATGATTTGGCTGAGAAGAGGAGAAGTAATGAGGTGCTACGTGGAGCCATCGAG
ACCTACCAAGAGGTGGCCAGCCTACCTGATGTCCCTGCAGACCTGCTGAAGCTGAGTTTGAAGCGTCGCTCAGACAGGCAACAATTTCTA
GGTCATATGAGAGGTTCCCTGCTTACCCTGCAGAGATTAGTTCAACTATTTCCCAATGATACTTCCTTAAAAAATGACCTTGGCGTGGGA
TACCTCTTGATAGGAGATAATGACAATGCAAAGAAAGTTTATGAAGAGGTGCTGAGTGTGACACCTAATGATGGCTTTGCTAAAGTCCAT
TATGGCTTCATCCTGAAGGCACAGAACAAAATTGCTGAGAGCATCCCATATTTAAAGGAAGGAATAGAATCCGGAGATCCTGGCACTGAT
GATGGGAGATTTTATTTCCACCTGGGGGATGCCATGCAGAGGGTTGGGAACAAAGAGGCATATAAGTGGTATGAGCTTGGGCACAAGAGA
GGACACTTTGCATCTGTCTGGCAACGCTCACTCTACAATGTGAATGGACTGAAAGCACAGCCTTGGTGGACCCCAAAAGAAACGGGCTAC
ACAGAGTTAGTAAAGTCTTTAGAAAGAAACTGGAAGTTAATCCGAGATGAAGGCCTTGCAGTGATGGATAAAGCCAAAGGTCTCTTCCTG
CCTGAGGATGAAAACCTGAGGGAAAAAGGGGACTGGAGCCAGTTCACGCTGTGGCAGCAAGGAAGAAGAAATGAAAATGCCTGCAAAGGA
GCTCCTAAAACCTGTACCTTACTAGAAAAGTTCCCCGAGACAACAGGATGCAGAAGAGGACAGATCAAATATTCCATCATGCACCCCGGG
ACTCACGTGTGGCCGCACACAGGGCCCACAAACTGCAGGCTCCGAATGCACCTGGGCTTGGTGATTCCCAAGGAAGGCTGCAAGATTCGA
TGTGCCAACGAGACCAAGACCTGGGAGGAAGGCAAGGTGCTCATCTTTGATGACTCCTTTGAGCACGAGGTATGGCAGGATGCCTCATCT
TTCCGGCTGATATTCATCGTGGATGTGTGGCATCCGGAACTGACACCACAGCAGAGACGCAGCCTTCCAGCAATTTAGCATGAATTCATG
CAAGCTTGGGAAACTCTGGAGAGAGGCTGCCTTTCTGGTTCCATCTCCTTGGGTGTGAGGATAGAATTTCGAACACCAAGAGTCAATTCC
CTTGACTTGCAGCCCGAGTAATTCAAAGCCTCCTCCTAGGGTCAGAAGACACTAAAGGGAATATTTGCCTCGCTGCAATTCATTTAGGAA
ACACCCTGCTGTGTGTCATCTCATGACAGCACTGGTCTTCTGCCAGTATTTAAGGTGAACATTTGATAGCTTCTACCTTACCAGCCAAAG
ATATTTTTTCCACATAGAATAGGTCTAATTCAATGTATAATGAGAACATATGTAGAAACTGTGAATGGATTGCTTTAGTTTGTAATTTTT
CTATGCAGTTATATTTTTCTAGTGTAGCTAGACTATTTTGTCATCATGTACCACTACATTTTTGTTTATTTTAATGACAAGCTGTATAAA
TGCTTTACTTCTAGCTATTTAATGGTAGCATTACTGGGGAACTCAGACTTCCCTCTTTTAATTCTTCTTAGTAAAAGATACTCATGAAAA
AAGCAGTTTTATTTTCCTAACAAAAAAGAAAGAGCTCATTATGTCAGTGTCTATGAACTGTACCCATCCCAACTCTCAAATCGTTTGGTT
TTTTTTATCTTGATTGAGATCCTCTTCTCACTATGCTAGTGGTGGAGATATTGACAAAATCCTATTTCTTTCAAAGAGGAACTTTTCACA
CCGAAAAAAGAGCATGGAATTATTTTATATTGTTATAAAAATCCCAGATGCAAATTTTTTTAATGCCAATTATTAGAGCTTCTGGGGAAA
AAGTATAGTTCACGGAAATAAAACTATGTTCTTTCAGGGTTGGGTGGATAGGTGGCTGCTAGGGTGTCTGGCTCCTGGCGGCTTTGCCAT
CCATGAGGCAAGGGCTGGGAACACAGTGTCTTTGCCTATGGTAGATCCATGTGAATGTCAGGAAGCCAGCTCTTCAGTCTTGGAGATGAT
TTCTGCTACAATTCTGTAGAAAGATTAAGGATGGCAGAGTAAAAGGTTACCAAGAATGCCAGGATGTTTTTCTTGGGCGTAGGAGGTCCA
GATTACTTTCCTTTTTGATGAAAGAGTTTGGAAGACTGTCCCATCTCTCTGGCTTGAGAAATCTCTGCCATTTTAAACATCACTGTGAAA
TAGCAATTATTATCATCTGTATTTAGTTTTAACATTACCCACAACATAGAAATAATAGGTAAAAATCGTCTTGCCTACTCATTCCAAAGA
TGATCAAGTCATTAATCTAGCAAAGTATTCATGTATCAGATTTTGTATATTTTGAATCAAAGCTAACTAGGAATGTTAGATATAAGAATG
TAATGATATTCATGCACTGAATTCTAAGCCAATATGAACAAAAATGCTGCATGAATGGCACATATAGGTCACCAAAGTTCATTCACAGGT
AGAAAAAACTTGTGCTTTCTTTTCCATCTAAAAACAAAAGGAGACTTTCTTTATCTCATTTAAAGAACAGCTCTTTGAAATTGAAATTGA
CCCTTTTTGCTTGACCTTAAGGAGATTAGCTTCCAGTAGATGAGTTTGCAAAATACTTTTCCTGTTCTTTTGTTTTGCTGGTATTGAAAA
CATCCCACTAAATCAGATGAAGAGGCATGGGAGGAAAAATATCCAAATTAATTACTAAAATCGAGAAGAGAAGGCAAACTCTTGAAAAGT
AAAAAGGTGTTTGTGACCTTCAGTATTTATTGAACAGAGGAAATAACTGACAAGGGCAATACAATTCAATGTTCATGTAGTAACATTCAT
GTCACTTGTTGAATTTGGTTCTCATATGTATATTGCATACACATAAATTCAAACTATAAGTCGTCATTTTTGAGCCATCATCTTACATTC
ATGTAATGAAATTATGGAAGAGAGTAAAAACTAGCTCTTAACTTAGTAAATATAATATGGTATTTAAAATCAGGTCACTACAGTAAGGTT
CTAAGTATTGCCAATTGAAAAGCTAGAAATGGTATTACTGTTGCAAAGTGTTGTCAATAATTGACTCCAATAGCATTGTAAATACTTGTA
TCCCACAACTATTTTAAACCCAAGCAATAAAATGGATTTTCTAATTCACTTCAATTCTTTATTTCTCTTACCTATCTATGTCTTGGTACA
TAAGAAAAGTGTTTCCATCACTGCATTGGTAGAATTATTTCAGTGTTATTATTTTTGTGATTTCGTATGTCTACACAAAAATGAATTAGT
TTAATTTATATTGTGATACAGTTGTTTGAGAAATATTTTTAATTCTGTTTCAACTTTATTTCTCCAAGTGTATAATATAAAAATTACTTC
TGTTATTGTTCTCTACCAATAGGGGAAAAAATTAAAACATTAGATCCATTGAGAAAGAGATGATGTAATAAATAATTAAGATTAGTAATA
ATATTATCAGGGGTGATTATGACCAGTTGAATAATCTCTTTCCCTTGAATTATTTAGCTAACAAATTAACTCTCCCAAATATTTAAAATA
ATGTAAAATCATATTTTACTGCCCATTATTAACTAAAATATTTTTGTTTGACTTTGAGCACCAACTGGTAATACTAATAAATACCCATGT
CATGCAGATGGCTGGGCGAATAAGAGATGTCTAAAAATATGCACTGGTCTTGGAAAACATGGCACAAGTAAGGATATCATATATGATGTC
TGTTTATTTTATGTCTGATTTCTTTTGAATGAGTAGTTGGGGACTCCATTTCTAAGGAGACTAGGTAAATAAAATGACCTTTGACATTTC

>74787_74787_2_RNF139-ASPH_RNF139_chr8_125487531_ENST00000303545_ASPH_chr8_62566219_ENST00000541428_length(amino acids)=773AA_BP=122
MPPPPAPPRGTRAGGGAGRERDRRGRRAGAELPALAPAPGRGPGPCPARPCPAHRALVWQRLMAAVGPPQQQVRMAHQQVWAALEVALRV
PCLYIIDAIFNSYPDSSQSRFCIVLQIFLRLFGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVE
GEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDV
TYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAEL
DAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVASLPDVPADLLKLSLKRRSDRQQFLGH
MRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKVYEEVLSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDDG
RFYFHLGDAMQRVGNKEAYKWYELGHKRGHFASVWQRSLYNVNGLKAQPWWTPKETGYTELVKSLERNWKLIRDEGLAVMDKAKGLFLPE
DENLREKGDWSQFTLWQQGRRNENACKGAPKTCTLLEKFPETTGCRRGQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RNF139-ASPH


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RNF139-ASPH


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RNF139-ASPH


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource