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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RNF170-SFRP1 (FusionGDB2 ID:74895)

Fusion Gene Summary for RNF170-SFRP1

check button Fusion gene summary
Fusion gene informationFusion gene name: RNF170-SFRP1
Fusion gene ID: 74895
HgeneTgene
Gene symbol

RNF170

SFRP1

Gene ID

81790

6422

Gene namering finger protein 170secreted frizzled related protein 1
SynonymsADSA|SNAX1FRP|FRP-1|FRP1|FrzA|SARP2
Cytomap

8p11.21

8p11.21

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase RNF170RING-type E3 ubiquitin transferase RNF170putative LAG1-interacting proteinsecreted frizzled-related protein 1SARP-2frizzled-related proteinsFRP-1secreted apoptosis-related protein 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000319073, ENST00000319104, 
ENST00000527424, ENST00000534961, 
ENST00000526349, 		ENST00000220772, 
ENST00000379845, 
Fusion gene scores* DoF score9 X 6 X 6=3244 X 5 X 4=80
# samples 105
** MAII scorelog2(10/324*10)=-1.6959938131099
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/80*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RNF170 [Title/Abstract] AND SFRP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRNF170(42742871)-SFRP1(41123008), # samples:3
Anticipated loss of major functional domain due to fusion event.RNF170-SFRP1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSFRP1

GO:0002244

hematopoietic progenitor cell differentiation

19778523

TgeneSFRP1

GO:0008284

positive regulation of cell proliferation

10980594

TgeneSFRP1

GO:0008285

negative regulation of cell proliferation

10347172|17443492|17994217|19277043|20208569

TgeneSFRP1

GO:0009950

dorsal/ventral axis specification

9192640

TgeneSFRP1

GO:0010629

negative regulation of gene expression

10980594

TgeneSFRP1

GO:0010719

negative regulation of epithelial to mesenchymal transition

19095296

TgeneSFRP1

GO:0014070

response to organic cyclic compound

20208569

TgeneSFRP1

GO:0030177

positive regulation of Wnt signaling pathway

10660608

TgeneSFRP1

GO:0030178

negative regulation of Wnt signaling pathway

9192640|10660608|17500071|20208569

TgeneSFRP1

GO:0030279

negative regulation of ossification

15677765

TgeneSFRP1

GO:0030307

positive regulation of cell growth

10980594|16288033

TgeneSFRP1

GO:0030308

negative regulation of cell growth

19569235|20208569

TgeneSFRP1

GO:0030336

negative regulation of cell migration

10980594

TgeneSFRP1

GO:0042493

response to drug

19072540|19254787

TgeneSFRP1

GO:0043065

positive regulation of apoptotic process

9391078|15677765

TgeneSFRP1

GO:0044344

cellular response to fibroblast growth factor stimulus

17500071

TgeneSFRP1

GO:0045600

positive regulation of fat cell differentiation

12055200|15886250

TgeneSFRP1

GO:0045892

negative regulation of transcription, DNA-templated

10660608|19095296|19277043|20234818

TgeneSFRP1

GO:0045893

positive regulation of transcription, DNA-templated

10660608|15886250|19569235

TgeneSFRP1

GO:0046676

negative regulation of insulin secretion

17994217

TgeneSFRP1

GO:0048147

negative regulation of fibroblast proliferation

19734317

TgeneSFRP1

GO:0050680

negative regulation of epithelial cell proliferation

19095296

TgeneSFRP1

GO:0050732

negative regulation of peptidyl-tyrosine phosphorylation

10980594

TgeneSFRP1

GO:0060070

canonical Wnt signaling pathway

18787224

TgeneSFRP1

GO:0060218

hematopoietic stem cell differentiation

19778523

TgeneSFRP1

GO:0060766

negative regulation of androgen receptor signaling pathway

19277043

TgeneSFRP1

GO:0071356

cellular response to tumor necrosis factor

9391078

TgeneSFRP1

GO:0071363

cellular response to growth factor stimulus

17500071

TgeneSFRP1

GO:0071391

cellular response to estrogen stimulus

18941195

TgeneSFRP1

GO:0071504

cellular response to heparin

17500071

TgeneSFRP1

GO:0090090

negative regulation of canonical Wnt signaling pathway

9391078|10347172|16149051|16288033|17443492|17471511|19095296|19277043|19569235

TgeneSFRP1

GO:0090263

positive regulation of canonical Wnt signaling pathway

18941195

TgeneSFRP1

GO:1902043

positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

9391078

TgeneSFRP1

GO:2000052

positive regulation of non-canonical Wnt signaling pathway

19569235

TgeneSFRP1

GO:2000054

negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification

9192640

TgeneSFRP1

GO:2000080

negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation

17994217

TgeneSFRP1

GO:2000270

negative regulation of fibroblast apoptotic process

14581477

TgeneSFRP1

GO:2000271

positive regulation of fibroblast apoptotic process

14581477


check buttonFusion gene breakpoints across RNF170 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SFRP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-50-6673-01ARNF170chr8

42742871

-SFRP1chr8

41123008

-
ChimerDB4LUADTCGA-50-6673RNF170chr8

42742870

-SFRP1chr8

41123008

-


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Fusion Gene ORF analysis for RNF170-SFRP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000319073ENST00000220772RNF170chr8

42742871

-SFRP1chr8

41123008

-
5UTR-3CDSENST00000319073ENST00000220772RNF170chr8

42742870

-SFRP1chr8

41123008

-
5UTR-3CDSENST00000319073ENST00000379845RNF170chr8

42742871

-SFRP1chr8

41123008

-
5UTR-3CDSENST00000319073ENST00000379845RNF170chr8

42742870

-SFRP1chr8

41123008

-
Frame-shiftENST00000319104ENST00000379845RNF170chr8

42742871

-SFRP1chr8

41123008

-
Frame-shiftENST00000319104ENST00000379845RNF170chr8

42742870

-SFRP1chr8

41123008

-
Frame-shiftENST00000527424ENST00000379845RNF170chr8

42742871

-SFRP1chr8

41123008

-
Frame-shiftENST00000527424ENST00000379845RNF170chr8

42742870

-SFRP1chr8

41123008

-
Frame-shiftENST00000534961ENST00000220772RNF170chr8

42742871

-SFRP1chr8

41123008

-
Frame-shiftENST00000534961ENST00000220772RNF170chr8

42742870

-SFRP1chr8

41123008

-
In-frameENST00000319104ENST00000220772RNF170chr8

42742871

-SFRP1chr8

41123008

-
In-frameENST00000319104ENST00000220772RNF170chr8

42742870

-SFRP1chr8

41123008

-
In-frameENST00000527424ENST00000220772RNF170chr8

42742871

-SFRP1chr8

41123008

-
In-frameENST00000527424ENST00000220772RNF170chr8

42742870

-SFRP1chr8

41123008

-
In-frameENST00000534961ENST00000379845RNF170chr8

42742871

-SFRP1chr8

41123008

-
In-frameENST00000534961ENST00000379845RNF170chr8

42742870

-SFRP1chr8

41123008

-
intron-3CDSENST00000526349ENST00000220772RNF170chr8

42742871

-SFRP1chr8

41123008

-
intron-3CDSENST00000526349ENST00000220772RNF170chr8

42742870

-SFRP1chr8

41123008

-
intron-3CDSENST00000526349ENST00000379845RNF170chr8

42742871

-SFRP1chr8

41123008

-
intron-3CDSENST00000526349ENST00000379845RNF170chr8

42742870

-SFRP1chr8

41123008

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000319104RNF170chr842742871-ENST00000220772SFRP1chr841123008-377424613387124
ENST00000534961RNF170chr842742871-ENST00000379845SFRP1chr841123008-41406145030168
ENST00000527424RNF170chr842742871-ENST00000220772SFRP1chr841123008-391038241523160
ENST00000319104RNF170chr842742870-ENST00000220772SFRP1chr841123008-377424613387124
ENST00000534961RNF170chr842742870-ENST00000379845SFRP1chr841123008-41406145030168
ENST00000527424RNF170chr842742870-ENST00000220772SFRP1chr841123008-391038241523160

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000319104ENST00000220772RNF170chr842742871-SFRP1chr841123008-0.0322876420.9677124
ENST00000534961ENST00000379845RNF170chr842742871-SFRP1chr841123008-0.0433608220.9566392
ENST00000527424ENST00000220772RNF170chr842742871-SFRP1chr841123008-0.032795170.9672048
ENST00000319104ENST00000220772RNF170chr842742870-SFRP1chr841123008-0.0322876420.9677124
ENST00000534961ENST00000379845RNF170chr842742870-SFRP1chr841123008-0.0433608220.9566392
ENST00000527424ENST00000220772RNF170chr842742870-SFRP1chr841123008-0.032795170.9672048

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Fusion Genomic Features for RNF170-SFRP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RNF170-SFRP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:42742871/chr8:41123008)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF170chr8:42742870chr8:41123008ENST00000319104-261_2445201.0Topological domainLumenal
HgeneRNF170chr8:42742870chr8:41123008ENST00000527424-271_2445259.0Topological domainLumenal
HgeneRNF170chr8:42742870chr8:41123008ENST00000534961-271_2445259.0Topological domainLumenal
HgeneRNF170chr8:42742871chr8:41123008ENST00000319104-261_2445201.0Topological domainLumenal
HgeneRNF170chr8:42742871chr8:41123008ENST00000527424-271_2445259.0Topological domainLumenal
HgeneRNF170chr8:42742871chr8:41123008ENST00000534961-271_2445259.0Topological domainLumenal
HgeneRNF170chr8:42742870chr8:41123008ENST00000319104-2625_4545201.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000527424-2725_4545259.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000534961-2725_4545259.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000319104-2625_4545201.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000527424-2725_4545259.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000534961-2725_4545259.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF170chr8:42742870chr8:41123008ENST00000319073-261_240163.0Topological domainLumenal
HgeneRNF170chr8:42742870chr8:41123008ENST00000319073-26223_2230163.0Topological domainLumenal
HgeneRNF170chr8:42742870chr8:41123008ENST00000319073-26245_2580163.0Topological domainCytoplasmic
HgeneRNF170chr8:42742870chr8:41123008ENST00000319073-2646_2010163.0Topological domainCytoplasmic
HgeneRNF170chr8:42742870chr8:41123008ENST00000319104-26223_22345201.0Topological domainLumenal
HgeneRNF170chr8:42742870chr8:41123008ENST00000319104-26245_25845201.0Topological domainCytoplasmic
HgeneRNF170chr8:42742870chr8:41123008ENST00000319104-2646_20145201.0Topological domainCytoplasmic
HgeneRNF170chr8:42742870chr8:41123008ENST00000526349-171_240175.0Topological domainLumenal
HgeneRNF170chr8:42742870chr8:41123008ENST00000526349-17223_2230175.0Topological domainLumenal
HgeneRNF170chr8:42742870chr8:41123008ENST00000526349-17245_2580175.0Topological domainCytoplasmic
HgeneRNF170chr8:42742870chr8:41123008ENST00000526349-1746_2010175.0Topological domainCytoplasmic
HgeneRNF170chr8:42742870chr8:41123008ENST00000527424-27223_22345259.0Topological domainLumenal
HgeneRNF170chr8:42742870chr8:41123008ENST00000527424-27245_25845259.0Topological domainCytoplasmic
HgeneRNF170chr8:42742870chr8:41123008ENST00000527424-2746_20145259.0Topological domainCytoplasmic
HgeneRNF170chr8:42742870chr8:41123008ENST00000534961-27223_22345259.0Topological domainLumenal
HgeneRNF170chr8:42742870chr8:41123008ENST00000534961-27245_25845259.0Topological domainCytoplasmic
HgeneRNF170chr8:42742870chr8:41123008ENST00000534961-2746_20145259.0Topological domainCytoplasmic
HgeneRNF170chr8:42742871chr8:41123008ENST00000319073-261_240163.0Topological domainLumenal
HgeneRNF170chr8:42742871chr8:41123008ENST00000319073-26223_2230163.0Topological domainLumenal
HgeneRNF170chr8:42742871chr8:41123008ENST00000319073-26245_2580163.0Topological domainCytoplasmic
HgeneRNF170chr8:42742871chr8:41123008ENST00000319073-2646_2010163.0Topological domainCytoplasmic
HgeneRNF170chr8:42742871chr8:41123008ENST00000319104-26223_22345201.0Topological domainLumenal
HgeneRNF170chr8:42742871chr8:41123008ENST00000319104-26245_25845201.0Topological domainCytoplasmic
HgeneRNF170chr8:42742871chr8:41123008ENST00000319104-2646_20145201.0Topological domainCytoplasmic
HgeneRNF170chr8:42742871chr8:41123008ENST00000526349-171_240175.0Topological domainLumenal
HgeneRNF170chr8:42742871chr8:41123008ENST00000526349-17223_2230175.0Topological domainLumenal
HgeneRNF170chr8:42742871chr8:41123008ENST00000526349-17245_2580175.0Topological domainCytoplasmic
HgeneRNF170chr8:42742871chr8:41123008ENST00000526349-1746_2010175.0Topological domainCytoplasmic
HgeneRNF170chr8:42742871chr8:41123008ENST00000527424-27223_22345259.0Topological domainLumenal
HgeneRNF170chr8:42742871chr8:41123008ENST00000527424-27245_25845259.0Topological domainCytoplasmic
HgeneRNF170chr8:42742871chr8:41123008ENST00000527424-2746_20145259.0Topological domainCytoplasmic
HgeneRNF170chr8:42742871chr8:41123008ENST00000534961-27223_22345259.0Topological domainLumenal
HgeneRNF170chr8:42742871chr8:41123008ENST00000534961-27245_25845259.0Topological domainCytoplasmic
HgeneRNF170chr8:42742871chr8:41123008ENST00000534961-2746_20145259.0Topological domainCytoplasmic
HgeneRNF170chr8:42742870chr8:41123008ENST00000319073-26202_2220163.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000319073-26224_2440163.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000319073-2625_450163.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000319104-26202_22245201.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000319104-26224_24445201.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000526349-17202_2220175.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000526349-17224_2440175.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000526349-1725_450175.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000527424-27202_22245259.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000527424-27224_24445259.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000534961-27202_22245259.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000534961-27224_24445259.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000319073-26202_2220163.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000319073-26224_2440163.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000319073-2625_450163.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000319104-26202_22245201.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000319104-26224_24445201.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000526349-17202_2220175.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000526349-17224_2440175.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000526349-1725_450175.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000527424-27202_22245259.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000527424-27224_24445259.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000534961-27202_22245259.0TransmembraneHelical
HgeneRNF170chr8:42742871chr8:41123008ENST00000534961-27224_24445259.0TransmembraneHelical
HgeneRNF170chr8:42742870chr8:41123008ENST00000319073-2687_1300163.0Zinc fingerRING-type
HgeneRNF170chr8:42742870chr8:41123008ENST00000319104-2687_13045201.0Zinc fingerRING-type
HgeneRNF170chr8:42742870chr8:41123008ENST00000526349-1787_1300175.0Zinc fingerRING-type
HgeneRNF170chr8:42742870chr8:41123008ENST00000527424-2787_13045259.0Zinc fingerRING-type
HgeneRNF170chr8:42742870chr8:41123008ENST00000534961-2787_13045259.0Zinc fingerRING-type
HgeneRNF170chr8:42742871chr8:41123008ENST00000319073-2687_1300163.0Zinc fingerRING-type
HgeneRNF170chr8:42742871chr8:41123008ENST00000319104-2687_13045201.0Zinc fingerRING-type
HgeneRNF170chr8:42742871chr8:41123008ENST00000526349-1787_1300175.0Zinc fingerRING-type
HgeneRNF170chr8:42742871chr8:41123008ENST00000527424-2787_13045259.0Zinc fingerRING-type
HgeneRNF170chr8:42742871chr8:41123008ENST00000534961-2787_13045259.0Zinc fingerRING-type
TgeneSFRP1chr8:42742870chr8:41123008ENST0000022077213186_306207315.0DomainNTR
TgeneSFRP1chr8:42742870chr8:41123008ENST000002207721353_169207315.0DomainFZ
TgeneSFRP1chr8:42742871chr8:41123008ENST0000022077213186_306207315.0DomainNTR
TgeneSFRP1chr8:42742871chr8:41123008ENST000002207721353_169207315.0DomainFZ


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Fusion Gene Sequence for RNF170-SFRP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>74895_74895_1_RNF170-SFRP1_RNF170_chr8_42742870_ENST00000319104_SFRP1_chr8_41123008_ENST00000220772_length(transcript)=3774nt_BP=246nt
GACGTCTAGTGGGTTGCCCGGGAGGGGTGGCGGGAGCGGTCCTGGAAATAATCTGTCCTCTGTCGCCGGGAACTGGCGAGGTAGTTCCTT
CGCGGTGGAGAGACCTGGAATGGCCAAATATCAAGGTGAAGTTCAAAGTTTGAAACTGGATGATGATTCAGTTATAGAAGGAGTAAGCGA
CCAAGTACTTGTGGCAGTTGTGGTCAGTTTCGCTTTGATTGCTACCCTGGTATATGCACTTTTCAGCACTGAGGATGAAAATAAAAGAAG
TGAAAAAAGAAAATGGCGACAAGAAGATTGTCCCCAAGAAGAAGAAGCCCCTGAAGTTGGGGCCCATCAAGAAGAAGGACCTGAAGAAGC
TTGTGCTGTACCTGAAGAATGGGGCTGACTGTCCCTGCCACCAGCTGGACAACCTCAGCCACCACTTCCTCATCATGGGCCGCAAGGTGA
AGAGCCAGTACTTGCTGACGGCCATCCACAAGTGGGACAAGAAAAACAAGGAGTTCAAAAACTTCATGAAGAAAATGAAAAACCATGAGT
GCCCCACCTTTCAGTCCGTGTTTAAGTGATTCTCCCGGGGGCAGGGTGGGGAGGGAGCCTCGGGTGGGGTGGGAGCGGGGGGGACAGTGC
CCCGGGAACCCGGTGGGTCACACACACGCACTGCGCCTGTCAGTAGTGGACATTGTAATCCAGTCGGCTTGTTCTTGCAGCATTCCCGCT
CCCTTCCCTCCATAGCCACGCTCCAAACCCCAGGGTAGCCATGGCCGGGTAAAGCAAGGGCCATTTAGATTAGGAAGGTTTTTAAGATCC
GCAATGTGGAGCAGCAGCCACTGCACAGGAGGAGGTGACAAACCATTTCCAACAGCAACACAGCCACTAAAACACAAAAAGGGGGATTGG
GCGGAAAGTGAGAGCCAGCAGCAAAAACTACATTTTGCAACTTGTTGGTGTGGATCTATTGGCTGATCTATGCCTTTCAACTAGAAAATT
CTAATGATTGGCAAGTCACGTTGTTTTCAGGTCCAGAGTAGTTTCTTTCTGTCTGCTTTAAATGGAAACAGACTCATACCACACTTACAA
TTAAGGTCAAGCCCAGAAAGTGATAAGTGCAGGGAGGAAAAGTGCAAGTCCATTATGTAATAGTGACAGCAAAGGGACCAGGGGAGAGGC
ATTGCCTTCTCTGCCCACAGTCTTTCCGTGTGATTGTCTTTGAATCTGAATCAGCCAGTCTCAGATGCCCCAAAGTTTCGGTTCCTATGA
GCCCGGGGCATGATCTGATCCCCAAGACATGTGGAGGGGCAGCCTGTGCCTGCCTTTGTGTCAGAAAAAGGAAACCACAGTGAGCCTGAG
AGAGACGGCGATTTTCGGGCTGAGAAGGCAGTAGTTTTCAAAACACATAGTTAAAAAAGAAACAAATGAAAAAAATTTTAGAACAGTCCA
GCAAATTGCTAGTCAGGGTGAATTGTGAAATTGGGTGAAGAGCTTAGGATTCTAATCTCATGTTTTTTCCTTTTCACATTTTTAAAAGAA
CAATGACAAACACCCACTTATTTTTCAAGGTTTTAAAACAGTCTACATTGAGCATTTGAAAGGTGTGCTAGAACAAGGTCTCCTGATCCG
TCCGAGGCTGCTTCCCAGAGGAGCAGCTCTCCCCAGGCATTTGCCAAGGGAGGCGGATTTCCCTGGTAGTGTAGCTGTGTGGCTTTCCTT
CCTGAAGAGTCCGTGGTTGCCCTAGAACCTAACACCCCCTAGCAAAACTCACAGAGCTTTCCGTTTTTTTCTTTCCTGTAAAGAAACATT
TCCTTTGAACTTGATTGCCTATGGATCAAAGAAATTCAGAACAGCCTGCCTGTCCCCCCGCACTTTTTACATATATTTGTTTCATTTCTG
CAGATGGAAAGTTGACATGGGTGGGGTGTCCCCATCCAGCGAGAGAGTTTCAAAAGCAAAACATCTCTGCAGTTTTTCCCAAGTACCCTG
AGATACTTCCCAAAGCCCTTATGTTTAATCAGCGATGTATATAAGCCAGTTCACTTAGACAACTTTACCCTTCTTGTCCAATGTACAGGA
AGTAGTTCTAAAAAAAATGCATATTAATTTCTTCCCCCAAAGCCGGATTCTTAATTCTCTGCAACACTTTGAGGACATTTATGATTGTCC
CTCTGGGCCAATGCTTATACCCAGTGAGGATGCTGCAGTGAGGCTGTAAAGTGGCCCCCTGCGGCCCTAGCCTGACCCGGAGGAAAGGAT
GGTAGATTCTGTTAACTCTTGAAGACTCCAGTATGAAAATCAGCATGCCCGCCTAGTTACCTACCGGAGAGTTATCCTGATAAATTAACC
TCTCACAGTTAGTGATCCTGTCCTTTTAACACCTTTTTTGTGGGGTTCTCTCTGACCTTTCATCGTAAAGTGCTGGGGACCTTAAGTGAT
TTGCCTGTAATTTTGGATGATTAAAAAATGTGTATATATATTAGCTAATTAGAAATATTCTACTTCTCTGTTGTCAAACTGAAATTCAGA
GCAAGTTCCTGAGTGCGTGGATCTGGGTCTTAGTTCTGGTTGATTCACTCAAGAGTTCAGTGCTCATACGTATCTGCTCATTTTGACAAA
GTGCCTCATGCAACCGGGCCCTCTCTCTGCGGCAGAGTCCTTAGTGGAGGGGTTTACCTGGAACATTAGTAGTTACCACAGAATACGGAA
GAGCAGGTGACTGTGCTGTGCAGCTCTCTAAATGGGAATTCTCAGGTAGGAAGCAACAGCTTCAGAAAGAGCTCAAAATAAATTGGAAAT
GTGAATCGCAGCTGTGGGTTTTACCACCGTCTGTCTCAGAGTCCCAGGACCTTGAGTGTCATTAGTTACTTTATTGAAGGTTTTAGACCC
ATAGCAGCTTTGTCTCTGTCACATCAGCAATTTCAGAACCAAAAGGGAGGCTCTCTGTAGGCACAGAGCTGCACTATCACGAGCCTTTGT
TTTTCTCCACAAAGTATCTAACAAAACCAATGTGCAGACTGATTGGCCTGGTCATTGGTCTCCGAGAGAGGAGGTTTGCCTGTGATTTCC
TAATTATCGCTAGGGCCAAGGTGGGATTTGTAAAGCTTTACAATAATCATTCTGGATAGAGTCCTGGGAGGTCCTTGGCAGAACTCAGTT
AAATCTTTGAAGAATATTTGTAGTTATCTTAGAAGATAGCATGGGAGGTGAGGATTCCAAAAACATTTTATTTTTAAAATATCCTGTGTA
ACACTTGGCTCTTGGTACCTGTGGGTTAGCATCAAGTTCTCCCCAGGGTAGAATTCAATCAGAGCTCCAGTTTGCATTTGGATGTGTAAA
TTACAGTAATCCCATTTCCCAAACCTAAAATCTGTTTTTCTCATCAGACTCTGAGTAACTGGTTGCTGTGTCATAACTTCATAGATGCAG
GAGGCTCAGGTGATCTGTTTGAGGAGAGCACCCTAGGCAGCCTGCAGGGAATAACATACTGGCCGTTCTGACCTGTTGCCAGCAGATACA
CAGGACATGGATGAAATTCCCGTTTCCTCTAGTTTCTTCCTGTAGTACTCCTCTTTTAGATCCTAAGTCTCTTACAAAAGCTTTGAATAC
TGTGAAAATGTTTTACATTCCATTTCATTTGTGTTGTTTTTTTAACTGCATTTTACCAGATGTTTTGATGTTATCGCTTATGTTAATAGT

>74895_74895_1_RNF170-SFRP1_RNF170_chr8_42742870_ENST00000319104_SFRP1_chr8_41123008_ENST00000220772_length(amino acids)=124AA_BP=77
MPGRGGGSGPGNNLSSVAGNWRGSSFAVERPGMAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFSTEDENKRSEKRK

--------------------------------------------------------------
>74895_74895_2_RNF170-SFRP1_RNF170_chr8_42742870_ENST00000527424_SFRP1_chr8_41123008_ENST00000220772_length(transcript)=3910nt_BP=382nt
TTCGCTGCGTGTCGAGGCGAGCACGCGCTCCGCCCTGGAGGCTGCGGCGACGGGTCCTCCTCCGCCGTCCGGTCGCGCCCTCGCGGAAGC
TCGGCAGTGCGCGTGCGCCCGCACCCGCACTCCAAATTAGAAAGGGGACGTCTAGTGGGTTGCCCGGGAGGGGTGGCGGGAGCGGTCCTG
GAAATAATCTGTCCTCTGTCGCCGGGAACTGGCGAGGTAGTTCCTTCGCGGTGGAGAGACCTGGAATGGCCAAATATCAAGGTGAAGTTC
AAAGTTTGAAACTGGATGATGATTCAGTTATAGAAGGAGTAAGCGACCAAGTACTTGTGGCAGTTGTGGTCAGTTTCGCTTTGATTGCTA
CCCTGGTATATGCACTTTTCAGCACTGAGGATGAAAATAAAAGAAGTGAAAAAAGAAAATGGCGACAAGAAGATTGTCCCCAAGAAGAAG
AAGCCCCTGAAGTTGGGGCCCATCAAGAAGAAGGACCTGAAGAAGCTTGTGCTGTACCTGAAGAATGGGGCTGACTGTCCCTGCCACCAG
CTGGACAACCTCAGCCACCACTTCCTCATCATGGGCCGCAAGGTGAAGAGCCAGTACTTGCTGACGGCCATCCACAAGTGGGACAAGAAA
AACAAGGAGTTCAAAAACTTCATGAAGAAAATGAAAAACCATGAGTGCCCCACCTTTCAGTCCGTGTTTAAGTGATTCTCCCGGGGGCAG
GGTGGGGAGGGAGCCTCGGGTGGGGTGGGAGCGGGGGGGACAGTGCCCCGGGAACCCGGTGGGTCACACACACGCACTGCGCCTGTCAGT
AGTGGACATTGTAATCCAGTCGGCTTGTTCTTGCAGCATTCCCGCTCCCTTCCCTCCATAGCCACGCTCCAAACCCCAGGGTAGCCATGG
CCGGGTAAAGCAAGGGCCATTTAGATTAGGAAGGTTTTTAAGATCCGCAATGTGGAGCAGCAGCCACTGCACAGGAGGAGGTGACAAACC
ATTTCCAACAGCAACACAGCCACTAAAACACAAAAAGGGGGATTGGGCGGAAAGTGAGAGCCAGCAGCAAAAACTACATTTTGCAACTTG
TTGGTGTGGATCTATTGGCTGATCTATGCCTTTCAACTAGAAAATTCTAATGATTGGCAAGTCACGTTGTTTTCAGGTCCAGAGTAGTTT
CTTTCTGTCTGCTTTAAATGGAAACAGACTCATACCACACTTACAATTAAGGTCAAGCCCAGAAAGTGATAAGTGCAGGGAGGAAAAGTG
CAAGTCCATTATGTAATAGTGACAGCAAAGGGACCAGGGGAGAGGCATTGCCTTCTCTGCCCACAGTCTTTCCGTGTGATTGTCTTTGAA
TCTGAATCAGCCAGTCTCAGATGCCCCAAAGTTTCGGTTCCTATGAGCCCGGGGCATGATCTGATCCCCAAGACATGTGGAGGGGCAGCC
TGTGCCTGCCTTTGTGTCAGAAAAAGGAAACCACAGTGAGCCTGAGAGAGACGGCGATTTTCGGGCTGAGAAGGCAGTAGTTTTCAAAAC
ACATAGTTAAAAAAGAAACAAATGAAAAAAATTTTAGAACAGTCCAGCAAATTGCTAGTCAGGGTGAATTGTGAAATTGGGTGAAGAGCT
TAGGATTCTAATCTCATGTTTTTTCCTTTTCACATTTTTAAAAGAACAATGACAAACACCCACTTATTTTTCAAGGTTTTAAAACAGTCT
ACATTGAGCATTTGAAAGGTGTGCTAGAACAAGGTCTCCTGATCCGTCCGAGGCTGCTTCCCAGAGGAGCAGCTCTCCCCAGGCATTTGC
CAAGGGAGGCGGATTTCCCTGGTAGTGTAGCTGTGTGGCTTTCCTTCCTGAAGAGTCCGTGGTTGCCCTAGAACCTAACACCCCCTAGCA
AAACTCACAGAGCTTTCCGTTTTTTTCTTTCCTGTAAAGAAACATTTCCTTTGAACTTGATTGCCTATGGATCAAAGAAATTCAGAACAG
CCTGCCTGTCCCCCCGCACTTTTTACATATATTTGTTTCATTTCTGCAGATGGAAAGTTGACATGGGTGGGGTGTCCCCATCCAGCGAGA
GAGTTTCAAAAGCAAAACATCTCTGCAGTTTTTCCCAAGTACCCTGAGATACTTCCCAAAGCCCTTATGTTTAATCAGCGATGTATATAA
GCCAGTTCACTTAGACAACTTTACCCTTCTTGTCCAATGTACAGGAAGTAGTTCTAAAAAAAATGCATATTAATTTCTTCCCCCAAAGCC
GGATTCTTAATTCTCTGCAACACTTTGAGGACATTTATGATTGTCCCTCTGGGCCAATGCTTATACCCAGTGAGGATGCTGCAGTGAGGC
TGTAAAGTGGCCCCCTGCGGCCCTAGCCTGACCCGGAGGAAAGGATGGTAGATTCTGTTAACTCTTGAAGACTCCAGTATGAAAATCAGC
ATGCCCGCCTAGTTACCTACCGGAGAGTTATCCTGATAAATTAACCTCTCACAGTTAGTGATCCTGTCCTTTTAACACCTTTTTTGTGGG
GTTCTCTCTGACCTTTCATCGTAAAGTGCTGGGGACCTTAAGTGATTTGCCTGTAATTTTGGATGATTAAAAAATGTGTATATATATTAG
CTAATTAGAAATATTCTACTTCTCTGTTGTCAAACTGAAATTCAGAGCAAGTTCCTGAGTGCGTGGATCTGGGTCTTAGTTCTGGTTGAT
TCACTCAAGAGTTCAGTGCTCATACGTATCTGCTCATTTTGACAAAGTGCCTCATGCAACCGGGCCCTCTCTCTGCGGCAGAGTCCTTAG
TGGAGGGGTTTACCTGGAACATTAGTAGTTACCACAGAATACGGAAGAGCAGGTGACTGTGCTGTGCAGCTCTCTAAATGGGAATTCTCA
GGTAGGAAGCAACAGCTTCAGAAAGAGCTCAAAATAAATTGGAAATGTGAATCGCAGCTGTGGGTTTTACCACCGTCTGTCTCAGAGTCC
CAGGACCTTGAGTGTCATTAGTTACTTTATTGAAGGTTTTAGACCCATAGCAGCTTTGTCTCTGTCACATCAGCAATTTCAGAACCAAAA
GGGAGGCTCTCTGTAGGCACAGAGCTGCACTATCACGAGCCTTTGTTTTTCTCCACAAAGTATCTAACAAAACCAATGTGCAGACTGATT
GGCCTGGTCATTGGTCTCCGAGAGAGGAGGTTTGCCTGTGATTTCCTAATTATCGCTAGGGCCAAGGTGGGATTTGTAAAGCTTTACAAT
AATCATTCTGGATAGAGTCCTGGGAGGTCCTTGGCAGAACTCAGTTAAATCTTTGAAGAATATTTGTAGTTATCTTAGAAGATAGCATGG
GAGGTGAGGATTCCAAAAACATTTTATTTTTAAAATATCCTGTGTAACACTTGGCTCTTGGTACCTGTGGGTTAGCATCAAGTTCTCCCC
AGGGTAGAATTCAATCAGAGCTCCAGTTTGCATTTGGATGTGTAAATTACAGTAATCCCATTTCCCAAACCTAAAATCTGTTTTTCTCAT
CAGACTCTGAGTAACTGGTTGCTGTGTCATAACTTCATAGATGCAGGAGGCTCAGGTGATCTGTTTGAGGAGAGCACCCTAGGCAGCCTG
CAGGGAATAACATACTGGCCGTTCTGACCTGTTGCCAGCAGATACACAGGACATGGATGAAATTCCCGTTTCCTCTAGTTTCTTCCTGTA
GTACTCCTCTTTTAGATCCTAAGTCTCTTACAAAAGCTTTGAATACTGTGAAAATGTTTTACATTCCATTTCATTTGTGTTGTTTTTTTA
ACTGCATTTTACCAGATGTTTTGATGTTATCGCTTATGTTAATAGTAATTCCCGTACGTGTTCATTTTATTTTCATGCTTTTTCAGCCAT

>74895_74895_2_RNF170-SFRP1_RNF170_chr8_42742870_ENST00000527424_SFRP1_chr8_41123008_ENST00000220772_length(amino acids)=160AA_BP=113
MRRRVLLRRPVAPSRKLGSARAPAPALQIRKGTSSGLPGRGGGSGPGNNLSSVAGNWRGSSFAVERPGMAKYQGEVQSLKLDDDSVIEGV

--------------------------------------------------------------
>74895_74895_3_RNF170-SFRP1_RNF170_chr8_42742870_ENST00000534961_SFRP1_chr8_41123008_ENST00000379845_length(transcript)=4140nt_BP=614nt
AGTTCGCTGCGTGTCGAGGCGAGCACGCGCTCCGCCCTGGAGGCTGCGGCGACGGGTCCTCCTCCGCCGTCCGGTCGCGCCCTCGCGGAA
GCTCGGCAGTGCGCGTGCGCCCGCACCCGCACTCCAAATTAGAAAGGGGACGTCTAGTGGGTTGCCCGGGAGGGGTGGCGGGAGCGGTCC
TGGAAATAATCTGTCCTCTGTCGCCGGGAACTGGCGAGGTAGTTCCTTCGCGGTGGAGAGGTACGTCCGGCGCGCGGCGGCCACGCCCAC
CCTATCGGGGCCCGCGGAGCCGCGGACGGCGGGGTCTGGCCTTCTTGGGGTAGCTCTGGCCGCCGAGGCTCTGCGGGGCGGCGGGAGTCG
CCGCCTCCTTCCCCCCGGGCCCCTCCCTCGTCTGGAAGCCCCAGAATCGCCCCGCGGCTGTCCGGAGTCGCCGGCGACGGTGGAGGGGCC
GACGCGGAGAGCGGCTCTAGACCTGGAATGGCCAAATATCAAGGTGAAGTTCAAAGTTTGAAACTGGATGATGATTCAGTTATAGAAGGA
GTAAGCGACCAAGTACTTGTGGCAGTTGTGGTCAGTTTCGCTTTGATTGCTACCCTGGTATATGCACTTTTCAGCACTGAGGATGAAAAT
AAAAGAAGTGAAAAAAGAAAATGGCGACAAGAAGATTGTCCCCAAGAAGAAGAAGCCCCTGAAGTTGGGGCCCATCAAGAAGAAGGACCT
GAAGAAGCTTGTGCTGTACCTGAAGAATGGGGCTGACTGTCCCTGCCACCAGCTGGACAACCTCAGCCACCACTTCCTCATCATGGGCCG
CAAGGTGAAGAGCCAGTACTTGCTGACGGCCATCCACAAGTGGGACAAGAAAAACAAGGAGTTCAAAAACTTCATGAAGAAAATGAAAAA
CCATGAGTGCCCCACCTTTCAGTCCGTGTTTAAGTGATTCTCCCGGGGGCAGGGTGGGGAGGGAGCCTCGGGTGGGGTGGGAGCGGGGGG
GACAGTGCCCCGGGAACCCGGTGGGTCACACACACGCACTGCGCCTGTCAGTAGTGGACATTGTAATCCAGTCGGCTTGTTCTTGCAGCA
TTCCCGCTCCCTTCCCTCCATAGCCACGCTCCAAACCCCAGGGTAGCCATGGCCGGGTAAAGCAAGGGCCATTTAGATTAGGAAGGTTTT
TAAGATCCGCAATGTGGAGCAGCAGCCACTGCACAGGAGGAGGTGACAAACCATTTCCAACAGCAACACAGCCACTAAAACACAAAAAGG
GGGATTGGGCGGAAAGTGAGAGCCAGCAGCAAAAACTACATTTTGCAACTTGTTGGTGTGGATCTATTGGCTGATCTATGCCTTTCAACT
AGAAAATTCTAATGATTGGCAAGTCACGTTGTTTTCAGGTCCAGAGTAGTTTCTTTCTGTCTGCTTTAAATGGAAACAGACTCATACCAC
ACTTACAATTAAGGTCAAGCCCAGAAAGTGATAAGTGCAGGGAGGAAAAGTGCAAGTCCATTATGTAATAGTGACAGCAAAGGGACCAGG
GGAGAGGCATTGCCTTCTCTGCCCACAGTCTTTCCGTGTGATTGTCTTTGAATCTGAATCAGCCAGTCTCAGATGCCCCAAAGTTTCGGT
TCCTATGAGCCCGGGGCATGATCTGATCCCCAAGACATGTGGAGGGGCAGCCTGTGCCTGCCTTTGTGTCAGAAAAAGGAAACCACAGTG
AGCCTGAGAGAGACGGCGATTTTCGGGCTGAGAAGGCAGTAGTTTTCAAAACACATAGTTAAAAAAGAAACAAATGAAAAAAATTTTAGA
ACAGTCCAGCAAATTGCTAGTCAGGGTGAATTGTGAAATTGGGTGAAGAGCTTAGGATTCTAATCTCATGTTTTTTCCTTTTCACATTTT
TAAAAGAACAATGACAAACACCCACTTATTTTTCAAGGTTTTAAAACAGTCTACATTGAGCATTTGAAAGGTGTGCTAGAACAAGGTCTC
CTGATCCGTCCGAGGCTGCTTCCCAGAGGAGCAGCTCTCCCCAGGCATTTGCCAAGGGAGGCGGATTTCCCTGGTAGTGTAGCTGTGTGG
CTTTCCTTCCTGAAGAGTCCGTGGTTGCCCTAGAACCTAACACCCCCTAGCAAAACTCACAGAGCTTTCCGTTTTTTTCTTTCCTGTAAA
GAAACATTTCCTTTGAACTTGATTGCCTATGGATCAAAGAAATTCAGAACAGCCTGCCTGTCCCCCCGCACTTTTTACATATATTTGTTT
CATTTCTGCAGATGGAAAGTTGACATGGGTGGGGTGTCCCCATCCAGCGAGAGAGTTTCAAAAGCAAAACATCTCTGCAGTTTTTCCCAA
GTACCCTGAGATACTTCCCAAAGCCCTTATGTTTAATCAGCGATGTATATAAGCCAGTTCACTTAGACAACTTTACCCTTCTTGTCCAAT
GTACAGGAAGTAGTTCTAAAAAAAATGCATATTAATTTCTTCCCCCAAAGCCGGATTCTTAATTCTCTGCAACACTTTGAGGACATTTAT
GATTGTCCCTCTGGGCCAATGCTTATACCCAGTGAGGATGCTGCAGTGAGGCTGTAAAGTGGCCCCCTGCGGCCCTAGCCTGACCCGGAG
GAAAGGATGGTAGATTCTGTTAACTCTTGAAGACTCCAGTATGAAAATCAGCATGCCCGCCTAGTTACCTACCGGAGAGTTATCCTGATA
AATTAACCTCTCACAGTTAGTGATCCTGTCCTTTTAACACCTTTTTTGTGGGGTTCTCTCTGACCTTTCATCGTAAAGTGCTGGGGACCT
TAAGTGATTTGCCTGTAATTTTGGATGATTAAAAAATGTGTATATATATTAGCTAATTAGAAATATTCTACTTCTCTGTTGTCAAACTGA
AATTCAGAGCAAGTTCCTGAGTGCGTGGATCTGGGTCTTAGTTCTGGTTGATTCACTCAAGAGTTCAGTGCTCATACGTATCTGCTCATT
TTGACAAAGTGCCTCATGCAACCGGGCCCTCTCTCTGCGGCAGAGTCCTTAGTGGAGGGGTTTACCTGGAACATTAGTAGTTACCACAGA
ATACGGAAGAGCAGGTGACTGTGCTGTGCAGCTCTCTAAATGGGAATTCTCAGGTAGGAAGCAACAGCTTCAGAAAGAGCTCAAAATAAA
TTGGAAATGTGAATCGCAGCTGTGGGTTTTACCACCGTCTGTCTCAGAGTCCCAGGACCTTGAGTGTCATTAGTTACTTTATTGAAGGTT
TTAGACCCATAGCAGCTTTGTCTCTGTCACATCAGCAATTTCAGAACCAAAAGGGAGGCTCTCTGTAGGCACAGAGCTGCACTATCACGA
GCCTTTGTTTTTCTCCACAAAGTATCTAACAAAACCAATGTGCAGACTGATTGGCCTGGTCATTGGTCTCCGAGAGAGGAGGTTTGCCTG
TGATTTCCTAATTATCGCTAGGGCCAAGGTGGGATTTGTAAAGCTTTACAATAATCATTCTGGATAGAGTCCTGGGAGGTCCTTGGCAGA
ACTCAGTTAAATCTTTGAAGAATATTTGTAGTTATCTTAGAAGATAGCATGGGAGGTGAGGATTCCAAAAACATTTTATTTTTAAAATAT
CCTGTGTAACACTTGGCTCTTGGTACCTGTGGGTTAGCATCAAGTTCTCCCCAGGGTAGAATTCAATCAGAGCTCCAGTTTGCATTTGGA
TGTGTAAATTACAGTAATCCCATTTCCCAAACCTAAAATCTGTTTTTCTCATCAGACTCTGAGTAACTGGTTGCTGTGTCATAACTTCAT
AGATGCAGGAGGCTCAGGTGATCTGTTTGAGGAGAGCACCCTAGGCAGCCTGCAGGGAATAACATACTGGCCGTTCTGACCTGTTGCCAG
CAGATACACAGGACATGGATGAAATTCCCGTTTCCTCTAGTTTCTTCCTGTAGTACTCCTCTTTTAGATCCTAAGTCTCTTACAAAAGCT
TTGAATACTGTGAAAATGTTTTACATTCCATTTCATTTGTGTTGTTTTTTTAACTGCATTTTACCAGATGTTTTGATGTTATCGCTTATG
TTAATAGTAATTCCCGTACGTGTTCATTTTATTTTCATGCTTTTTCAGCCATGTATCAATATTCACTTGACTAAAATCACTCAATTAATC

>74895_74895_3_RNF170-SFRP1_RNF170_chr8_42742870_ENST00000534961_SFRP1_chr8_41123008_ENST00000379845_length(amino acids)=168AA_BP=
MNFTLIFGHSRSRAALRVGPSTVAGDSGQPRGDSGASRRGRGPGGRRRRLPPPRRASAARATPRRPDPAVRGSAGPDRVGVAAARRTYLS

--------------------------------------------------------------
>74895_74895_4_RNF170-SFRP1_RNF170_chr8_42742871_ENST00000319104_SFRP1_chr8_41123008_ENST00000220772_length(transcript)=3774nt_BP=246nt
GACGTCTAGTGGGTTGCCCGGGAGGGGTGGCGGGAGCGGTCCTGGAAATAATCTGTCCTCTGTCGCCGGGAACTGGCGAGGTAGTTCCTT
CGCGGTGGAGAGACCTGGAATGGCCAAATATCAAGGTGAAGTTCAAAGTTTGAAACTGGATGATGATTCAGTTATAGAAGGAGTAAGCGA
CCAAGTACTTGTGGCAGTTGTGGTCAGTTTCGCTTTGATTGCTACCCTGGTATATGCACTTTTCAGCACTGAGGATGAAAATAAAAGAAG
TGAAAAAAGAAAATGGCGACAAGAAGATTGTCCCCAAGAAGAAGAAGCCCCTGAAGTTGGGGCCCATCAAGAAGAAGGACCTGAAGAAGC
TTGTGCTGTACCTGAAGAATGGGGCTGACTGTCCCTGCCACCAGCTGGACAACCTCAGCCACCACTTCCTCATCATGGGCCGCAAGGTGA
AGAGCCAGTACTTGCTGACGGCCATCCACAAGTGGGACAAGAAAAACAAGGAGTTCAAAAACTTCATGAAGAAAATGAAAAACCATGAGT
GCCCCACCTTTCAGTCCGTGTTTAAGTGATTCTCCCGGGGGCAGGGTGGGGAGGGAGCCTCGGGTGGGGTGGGAGCGGGGGGGACAGTGC
CCCGGGAACCCGGTGGGTCACACACACGCACTGCGCCTGTCAGTAGTGGACATTGTAATCCAGTCGGCTTGTTCTTGCAGCATTCCCGCT
CCCTTCCCTCCATAGCCACGCTCCAAACCCCAGGGTAGCCATGGCCGGGTAAAGCAAGGGCCATTTAGATTAGGAAGGTTTTTAAGATCC
GCAATGTGGAGCAGCAGCCACTGCACAGGAGGAGGTGACAAACCATTTCCAACAGCAACACAGCCACTAAAACACAAAAAGGGGGATTGG
GCGGAAAGTGAGAGCCAGCAGCAAAAACTACATTTTGCAACTTGTTGGTGTGGATCTATTGGCTGATCTATGCCTTTCAACTAGAAAATT
CTAATGATTGGCAAGTCACGTTGTTTTCAGGTCCAGAGTAGTTTCTTTCTGTCTGCTTTAAATGGAAACAGACTCATACCACACTTACAA
TTAAGGTCAAGCCCAGAAAGTGATAAGTGCAGGGAGGAAAAGTGCAAGTCCATTATGTAATAGTGACAGCAAAGGGACCAGGGGAGAGGC
ATTGCCTTCTCTGCCCACAGTCTTTCCGTGTGATTGTCTTTGAATCTGAATCAGCCAGTCTCAGATGCCCCAAAGTTTCGGTTCCTATGA
GCCCGGGGCATGATCTGATCCCCAAGACATGTGGAGGGGCAGCCTGTGCCTGCCTTTGTGTCAGAAAAAGGAAACCACAGTGAGCCTGAG
AGAGACGGCGATTTTCGGGCTGAGAAGGCAGTAGTTTTCAAAACACATAGTTAAAAAAGAAACAAATGAAAAAAATTTTAGAACAGTCCA
GCAAATTGCTAGTCAGGGTGAATTGTGAAATTGGGTGAAGAGCTTAGGATTCTAATCTCATGTTTTTTCCTTTTCACATTTTTAAAAGAA
CAATGACAAACACCCACTTATTTTTCAAGGTTTTAAAACAGTCTACATTGAGCATTTGAAAGGTGTGCTAGAACAAGGTCTCCTGATCCG
TCCGAGGCTGCTTCCCAGAGGAGCAGCTCTCCCCAGGCATTTGCCAAGGGAGGCGGATTTCCCTGGTAGTGTAGCTGTGTGGCTTTCCTT
CCTGAAGAGTCCGTGGTTGCCCTAGAACCTAACACCCCCTAGCAAAACTCACAGAGCTTTCCGTTTTTTTCTTTCCTGTAAAGAAACATT
TCCTTTGAACTTGATTGCCTATGGATCAAAGAAATTCAGAACAGCCTGCCTGTCCCCCCGCACTTTTTACATATATTTGTTTCATTTCTG
CAGATGGAAAGTTGACATGGGTGGGGTGTCCCCATCCAGCGAGAGAGTTTCAAAAGCAAAACATCTCTGCAGTTTTTCCCAAGTACCCTG
AGATACTTCCCAAAGCCCTTATGTTTAATCAGCGATGTATATAAGCCAGTTCACTTAGACAACTTTACCCTTCTTGTCCAATGTACAGGA
AGTAGTTCTAAAAAAAATGCATATTAATTTCTTCCCCCAAAGCCGGATTCTTAATTCTCTGCAACACTTTGAGGACATTTATGATTGTCC
CTCTGGGCCAATGCTTATACCCAGTGAGGATGCTGCAGTGAGGCTGTAAAGTGGCCCCCTGCGGCCCTAGCCTGACCCGGAGGAAAGGAT
GGTAGATTCTGTTAACTCTTGAAGACTCCAGTATGAAAATCAGCATGCCCGCCTAGTTACCTACCGGAGAGTTATCCTGATAAATTAACC
TCTCACAGTTAGTGATCCTGTCCTTTTAACACCTTTTTTGTGGGGTTCTCTCTGACCTTTCATCGTAAAGTGCTGGGGACCTTAAGTGAT
TTGCCTGTAATTTTGGATGATTAAAAAATGTGTATATATATTAGCTAATTAGAAATATTCTACTTCTCTGTTGTCAAACTGAAATTCAGA
GCAAGTTCCTGAGTGCGTGGATCTGGGTCTTAGTTCTGGTTGATTCACTCAAGAGTTCAGTGCTCATACGTATCTGCTCATTTTGACAAA
GTGCCTCATGCAACCGGGCCCTCTCTCTGCGGCAGAGTCCTTAGTGGAGGGGTTTACCTGGAACATTAGTAGTTACCACAGAATACGGAA
GAGCAGGTGACTGTGCTGTGCAGCTCTCTAAATGGGAATTCTCAGGTAGGAAGCAACAGCTTCAGAAAGAGCTCAAAATAAATTGGAAAT
GTGAATCGCAGCTGTGGGTTTTACCACCGTCTGTCTCAGAGTCCCAGGACCTTGAGTGTCATTAGTTACTTTATTGAAGGTTTTAGACCC
ATAGCAGCTTTGTCTCTGTCACATCAGCAATTTCAGAACCAAAAGGGAGGCTCTCTGTAGGCACAGAGCTGCACTATCACGAGCCTTTGT
TTTTCTCCACAAAGTATCTAACAAAACCAATGTGCAGACTGATTGGCCTGGTCATTGGTCTCCGAGAGAGGAGGTTTGCCTGTGATTTCC
TAATTATCGCTAGGGCCAAGGTGGGATTTGTAAAGCTTTACAATAATCATTCTGGATAGAGTCCTGGGAGGTCCTTGGCAGAACTCAGTT
AAATCTTTGAAGAATATTTGTAGTTATCTTAGAAGATAGCATGGGAGGTGAGGATTCCAAAAACATTTTATTTTTAAAATATCCTGTGTA
ACACTTGGCTCTTGGTACCTGTGGGTTAGCATCAAGTTCTCCCCAGGGTAGAATTCAATCAGAGCTCCAGTTTGCATTTGGATGTGTAAA
TTACAGTAATCCCATTTCCCAAACCTAAAATCTGTTTTTCTCATCAGACTCTGAGTAACTGGTTGCTGTGTCATAACTTCATAGATGCAG
GAGGCTCAGGTGATCTGTTTGAGGAGAGCACCCTAGGCAGCCTGCAGGGAATAACATACTGGCCGTTCTGACCTGTTGCCAGCAGATACA
CAGGACATGGATGAAATTCCCGTTTCCTCTAGTTTCTTCCTGTAGTACTCCTCTTTTAGATCCTAAGTCTCTTACAAAAGCTTTGAATAC
TGTGAAAATGTTTTACATTCCATTTCATTTGTGTTGTTTTTTTAACTGCATTTTACCAGATGTTTTGATGTTATCGCTTATGTTAATAGT

>74895_74895_4_RNF170-SFRP1_RNF170_chr8_42742871_ENST00000319104_SFRP1_chr8_41123008_ENST00000220772_length(amino acids)=124AA_BP=77
MPGRGGGSGPGNNLSSVAGNWRGSSFAVERPGMAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFSTEDENKRSEKRK

--------------------------------------------------------------
>74895_74895_5_RNF170-SFRP1_RNF170_chr8_42742871_ENST00000527424_SFRP1_chr8_41123008_ENST00000220772_length(transcript)=3910nt_BP=382nt
TTCGCTGCGTGTCGAGGCGAGCACGCGCTCCGCCCTGGAGGCTGCGGCGACGGGTCCTCCTCCGCCGTCCGGTCGCGCCCTCGCGGAAGC
TCGGCAGTGCGCGTGCGCCCGCACCCGCACTCCAAATTAGAAAGGGGACGTCTAGTGGGTTGCCCGGGAGGGGTGGCGGGAGCGGTCCTG
GAAATAATCTGTCCTCTGTCGCCGGGAACTGGCGAGGTAGTTCCTTCGCGGTGGAGAGACCTGGAATGGCCAAATATCAAGGTGAAGTTC
AAAGTTTGAAACTGGATGATGATTCAGTTATAGAAGGAGTAAGCGACCAAGTACTTGTGGCAGTTGTGGTCAGTTTCGCTTTGATTGCTA
CCCTGGTATATGCACTTTTCAGCACTGAGGATGAAAATAAAAGAAGTGAAAAAAGAAAATGGCGACAAGAAGATTGTCCCCAAGAAGAAG
AAGCCCCTGAAGTTGGGGCCCATCAAGAAGAAGGACCTGAAGAAGCTTGTGCTGTACCTGAAGAATGGGGCTGACTGTCCCTGCCACCAG
CTGGACAACCTCAGCCACCACTTCCTCATCATGGGCCGCAAGGTGAAGAGCCAGTACTTGCTGACGGCCATCCACAAGTGGGACAAGAAA
AACAAGGAGTTCAAAAACTTCATGAAGAAAATGAAAAACCATGAGTGCCCCACCTTTCAGTCCGTGTTTAAGTGATTCTCCCGGGGGCAG
GGTGGGGAGGGAGCCTCGGGTGGGGTGGGAGCGGGGGGGACAGTGCCCCGGGAACCCGGTGGGTCACACACACGCACTGCGCCTGTCAGT
AGTGGACATTGTAATCCAGTCGGCTTGTTCTTGCAGCATTCCCGCTCCCTTCCCTCCATAGCCACGCTCCAAACCCCAGGGTAGCCATGG
CCGGGTAAAGCAAGGGCCATTTAGATTAGGAAGGTTTTTAAGATCCGCAATGTGGAGCAGCAGCCACTGCACAGGAGGAGGTGACAAACC
ATTTCCAACAGCAACACAGCCACTAAAACACAAAAAGGGGGATTGGGCGGAAAGTGAGAGCCAGCAGCAAAAACTACATTTTGCAACTTG
TTGGTGTGGATCTATTGGCTGATCTATGCCTTTCAACTAGAAAATTCTAATGATTGGCAAGTCACGTTGTTTTCAGGTCCAGAGTAGTTT
CTTTCTGTCTGCTTTAAATGGAAACAGACTCATACCACACTTACAATTAAGGTCAAGCCCAGAAAGTGATAAGTGCAGGGAGGAAAAGTG
CAAGTCCATTATGTAATAGTGACAGCAAAGGGACCAGGGGAGAGGCATTGCCTTCTCTGCCCACAGTCTTTCCGTGTGATTGTCTTTGAA
TCTGAATCAGCCAGTCTCAGATGCCCCAAAGTTTCGGTTCCTATGAGCCCGGGGCATGATCTGATCCCCAAGACATGTGGAGGGGCAGCC
TGTGCCTGCCTTTGTGTCAGAAAAAGGAAACCACAGTGAGCCTGAGAGAGACGGCGATTTTCGGGCTGAGAAGGCAGTAGTTTTCAAAAC
ACATAGTTAAAAAAGAAACAAATGAAAAAAATTTTAGAACAGTCCAGCAAATTGCTAGTCAGGGTGAATTGTGAAATTGGGTGAAGAGCT
TAGGATTCTAATCTCATGTTTTTTCCTTTTCACATTTTTAAAAGAACAATGACAAACACCCACTTATTTTTCAAGGTTTTAAAACAGTCT
ACATTGAGCATTTGAAAGGTGTGCTAGAACAAGGTCTCCTGATCCGTCCGAGGCTGCTTCCCAGAGGAGCAGCTCTCCCCAGGCATTTGC
CAAGGGAGGCGGATTTCCCTGGTAGTGTAGCTGTGTGGCTTTCCTTCCTGAAGAGTCCGTGGTTGCCCTAGAACCTAACACCCCCTAGCA
AAACTCACAGAGCTTTCCGTTTTTTTCTTTCCTGTAAAGAAACATTTCCTTTGAACTTGATTGCCTATGGATCAAAGAAATTCAGAACAG
CCTGCCTGTCCCCCCGCACTTTTTACATATATTTGTTTCATTTCTGCAGATGGAAAGTTGACATGGGTGGGGTGTCCCCATCCAGCGAGA
GAGTTTCAAAAGCAAAACATCTCTGCAGTTTTTCCCAAGTACCCTGAGATACTTCCCAAAGCCCTTATGTTTAATCAGCGATGTATATAA
GCCAGTTCACTTAGACAACTTTACCCTTCTTGTCCAATGTACAGGAAGTAGTTCTAAAAAAAATGCATATTAATTTCTTCCCCCAAAGCC
GGATTCTTAATTCTCTGCAACACTTTGAGGACATTTATGATTGTCCCTCTGGGCCAATGCTTATACCCAGTGAGGATGCTGCAGTGAGGC
TGTAAAGTGGCCCCCTGCGGCCCTAGCCTGACCCGGAGGAAAGGATGGTAGATTCTGTTAACTCTTGAAGACTCCAGTATGAAAATCAGC
ATGCCCGCCTAGTTACCTACCGGAGAGTTATCCTGATAAATTAACCTCTCACAGTTAGTGATCCTGTCCTTTTAACACCTTTTTTGTGGG
GTTCTCTCTGACCTTTCATCGTAAAGTGCTGGGGACCTTAAGTGATTTGCCTGTAATTTTGGATGATTAAAAAATGTGTATATATATTAG
CTAATTAGAAATATTCTACTTCTCTGTTGTCAAACTGAAATTCAGAGCAAGTTCCTGAGTGCGTGGATCTGGGTCTTAGTTCTGGTTGAT
TCACTCAAGAGTTCAGTGCTCATACGTATCTGCTCATTTTGACAAAGTGCCTCATGCAACCGGGCCCTCTCTCTGCGGCAGAGTCCTTAG
TGGAGGGGTTTACCTGGAACATTAGTAGTTACCACAGAATACGGAAGAGCAGGTGACTGTGCTGTGCAGCTCTCTAAATGGGAATTCTCA
GGTAGGAAGCAACAGCTTCAGAAAGAGCTCAAAATAAATTGGAAATGTGAATCGCAGCTGTGGGTTTTACCACCGTCTGTCTCAGAGTCC
CAGGACCTTGAGTGTCATTAGTTACTTTATTGAAGGTTTTAGACCCATAGCAGCTTTGTCTCTGTCACATCAGCAATTTCAGAACCAAAA
GGGAGGCTCTCTGTAGGCACAGAGCTGCACTATCACGAGCCTTTGTTTTTCTCCACAAAGTATCTAACAAAACCAATGTGCAGACTGATT
GGCCTGGTCATTGGTCTCCGAGAGAGGAGGTTTGCCTGTGATTTCCTAATTATCGCTAGGGCCAAGGTGGGATTTGTAAAGCTTTACAAT
AATCATTCTGGATAGAGTCCTGGGAGGTCCTTGGCAGAACTCAGTTAAATCTTTGAAGAATATTTGTAGTTATCTTAGAAGATAGCATGG
GAGGTGAGGATTCCAAAAACATTTTATTTTTAAAATATCCTGTGTAACACTTGGCTCTTGGTACCTGTGGGTTAGCATCAAGTTCTCCCC
AGGGTAGAATTCAATCAGAGCTCCAGTTTGCATTTGGATGTGTAAATTACAGTAATCCCATTTCCCAAACCTAAAATCTGTTTTTCTCAT
CAGACTCTGAGTAACTGGTTGCTGTGTCATAACTTCATAGATGCAGGAGGCTCAGGTGATCTGTTTGAGGAGAGCACCCTAGGCAGCCTG
CAGGGAATAACATACTGGCCGTTCTGACCTGTTGCCAGCAGATACACAGGACATGGATGAAATTCCCGTTTCCTCTAGTTTCTTCCTGTA
GTACTCCTCTTTTAGATCCTAAGTCTCTTACAAAAGCTTTGAATACTGTGAAAATGTTTTACATTCCATTTCATTTGTGTTGTTTTTTTA
ACTGCATTTTACCAGATGTTTTGATGTTATCGCTTATGTTAATAGTAATTCCCGTACGTGTTCATTTTATTTTCATGCTTTTTCAGCCAT

>74895_74895_5_RNF170-SFRP1_RNF170_chr8_42742871_ENST00000527424_SFRP1_chr8_41123008_ENST00000220772_length(amino acids)=160AA_BP=113
MRRRVLLRRPVAPSRKLGSARAPAPALQIRKGTSSGLPGRGGGSGPGNNLSSVAGNWRGSSFAVERPGMAKYQGEVQSLKLDDDSVIEGV

--------------------------------------------------------------
>74895_74895_6_RNF170-SFRP1_RNF170_chr8_42742871_ENST00000534961_SFRP1_chr8_41123008_ENST00000379845_length(transcript)=4140nt_BP=614nt
AGTTCGCTGCGTGTCGAGGCGAGCACGCGCTCCGCCCTGGAGGCTGCGGCGACGGGTCCTCCTCCGCCGTCCGGTCGCGCCCTCGCGGAA
GCTCGGCAGTGCGCGTGCGCCCGCACCCGCACTCCAAATTAGAAAGGGGACGTCTAGTGGGTTGCCCGGGAGGGGTGGCGGGAGCGGTCC
TGGAAATAATCTGTCCTCTGTCGCCGGGAACTGGCGAGGTAGTTCCTTCGCGGTGGAGAGGTACGTCCGGCGCGCGGCGGCCACGCCCAC
CCTATCGGGGCCCGCGGAGCCGCGGACGGCGGGGTCTGGCCTTCTTGGGGTAGCTCTGGCCGCCGAGGCTCTGCGGGGCGGCGGGAGTCG
CCGCCTCCTTCCCCCCGGGCCCCTCCCTCGTCTGGAAGCCCCAGAATCGCCCCGCGGCTGTCCGGAGTCGCCGGCGACGGTGGAGGGGCC
GACGCGGAGAGCGGCTCTAGACCTGGAATGGCCAAATATCAAGGTGAAGTTCAAAGTTTGAAACTGGATGATGATTCAGTTATAGAAGGA
GTAAGCGACCAAGTACTTGTGGCAGTTGTGGTCAGTTTCGCTTTGATTGCTACCCTGGTATATGCACTTTTCAGCACTGAGGATGAAAAT
AAAAGAAGTGAAAAAAGAAAATGGCGACAAGAAGATTGTCCCCAAGAAGAAGAAGCCCCTGAAGTTGGGGCCCATCAAGAAGAAGGACCT
GAAGAAGCTTGTGCTGTACCTGAAGAATGGGGCTGACTGTCCCTGCCACCAGCTGGACAACCTCAGCCACCACTTCCTCATCATGGGCCG
CAAGGTGAAGAGCCAGTACTTGCTGACGGCCATCCACAAGTGGGACAAGAAAAACAAGGAGTTCAAAAACTTCATGAAGAAAATGAAAAA
CCATGAGTGCCCCACCTTTCAGTCCGTGTTTAAGTGATTCTCCCGGGGGCAGGGTGGGGAGGGAGCCTCGGGTGGGGTGGGAGCGGGGGG
GACAGTGCCCCGGGAACCCGGTGGGTCACACACACGCACTGCGCCTGTCAGTAGTGGACATTGTAATCCAGTCGGCTTGTTCTTGCAGCA
TTCCCGCTCCCTTCCCTCCATAGCCACGCTCCAAACCCCAGGGTAGCCATGGCCGGGTAAAGCAAGGGCCATTTAGATTAGGAAGGTTTT
TAAGATCCGCAATGTGGAGCAGCAGCCACTGCACAGGAGGAGGTGACAAACCATTTCCAACAGCAACACAGCCACTAAAACACAAAAAGG
GGGATTGGGCGGAAAGTGAGAGCCAGCAGCAAAAACTACATTTTGCAACTTGTTGGTGTGGATCTATTGGCTGATCTATGCCTTTCAACT
AGAAAATTCTAATGATTGGCAAGTCACGTTGTTTTCAGGTCCAGAGTAGTTTCTTTCTGTCTGCTTTAAATGGAAACAGACTCATACCAC
ACTTACAATTAAGGTCAAGCCCAGAAAGTGATAAGTGCAGGGAGGAAAAGTGCAAGTCCATTATGTAATAGTGACAGCAAAGGGACCAGG
GGAGAGGCATTGCCTTCTCTGCCCACAGTCTTTCCGTGTGATTGTCTTTGAATCTGAATCAGCCAGTCTCAGATGCCCCAAAGTTTCGGT
TCCTATGAGCCCGGGGCATGATCTGATCCCCAAGACATGTGGAGGGGCAGCCTGTGCCTGCCTTTGTGTCAGAAAAAGGAAACCACAGTG
AGCCTGAGAGAGACGGCGATTTTCGGGCTGAGAAGGCAGTAGTTTTCAAAACACATAGTTAAAAAAGAAACAAATGAAAAAAATTTTAGA
ACAGTCCAGCAAATTGCTAGTCAGGGTGAATTGTGAAATTGGGTGAAGAGCTTAGGATTCTAATCTCATGTTTTTTCCTTTTCACATTTT
TAAAAGAACAATGACAAACACCCACTTATTTTTCAAGGTTTTAAAACAGTCTACATTGAGCATTTGAAAGGTGTGCTAGAACAAGGTCTC
CTGATCCGTCCGAGGCTGCTTCCCAGAGGAGCAGCTCTCCCCAGGCATTTGCCAAGGGAGGCGGATTTCCCTGGTAGTGTAGCTGTGTGG
CTTTCCTTCCTGAAGAGTCCGTGGTTGCCCTAGAACCTAACACCCCCTAGCAAAACTCACAGAGCTTTCCGTTTTTTTCTTTCCTGTAAA
GAAACATTTCCTTTGAACTTGATTGCCTATGGATCAAAGAAATTCAGAACAGCCTGCCTGTCCCCCCGCACTTTTTACATATATTTGTTT
CATTTCTGCAGATGGAAAGTTGACATGGGTGGGGTGTCCCCATCCAGCGAGAGAGTTTCAAAAGCAAAACATCTCTGCAGTTTTTCCCAA
GTACCCTGAGATACTTCCCAAAGCCCTTATGTTTAATCAGCGATGTATATAAGCCAGTTCACTTAGACAACTTTACCCTTCTTGTCCAAT
GTACAGGAAGTAGTTCTAAAAAAAATGCATATTAATTTCTTCCCCCAAAGCCGGATTCTTAATTCTCTGCAACACTTTGAGGACATTTAT
GATTGTCCCTCTGGGCCAATGCTTATACCCAGTGAGGATGCTGCAGTGAGGCTGTAAAGTGGCCCCCTGCGGCCCTAGCCTGACCCGGAG
GAAAGGATGGTAGATTCTGTTAACTCTTGAAGACTCCAGTATGAAAATCAGCATGCCCGCCTAGTTACCTACCGGAGAGTTATCCTGATA
AATTAACCTCTCACAGTTAGTGATCCTGTCCTTTTAACACCTTTTTTGTGGGGTTCTCTCTGACCTTTCATCGTAAAGTGCTGGGGACCT
TAAGTGATTTGCCTGTAATTTTGGATGATTAAAAAATGTGTATATATATTAGCTAATTAGAAATATTCTACTTCTCTGTTGTCAAACTGA
AATTCAGAGCAAGTTCCTGAGTGCGTGGATCTGGGTCTTAGTTCTGGTTGATTCACTCAAGAGTTCAGTGCTCATACGTATCTGCTCATT
TTGACAAAGTGCCTCATGCAACCGGGCCCTCTCTCTGCGGCAGAGTCCTTAGTGGAGGGGTTTACCTGGAACATTAGTAGTTACCACAGA
ATACGGAAGAGCAGGTGACTGTGCTGTGCAGCTCTCTAAATGGGAATTCTCAGGTAGGAAGCAACAGCTTCAGAAAGAGCTCAAAATAAA
TTGGAAATGTGAATCGCAGCTGTGGGTTTTACCACCGTCTGTCTCAGAGTCCCAGGACCTTGAGTGTCATTAGTTACTTTATTGAAGGTT
TTAGACCCATAGCAGCTTTGTCTCTGTCACATCAGCAATTTCAGAACCAAAAGGGAGGCTCTCTGTAGGCACAGAGCTGCACTATCACGA
GCCTTTGTTTTTCTCCACAAAGTATCTAACAAAACCAATGTGCAGACTGATTGGCCTGGTCATTGGTCTCCGAGAGAGGAGGTTTGCCTG
TGATTTCCTAATTATCGCTAGGGCCAAGGTGGGATTTGTAAAGCTTTACAATAATCATTCTGGATAGAGTCCTGGGAGGTCCTTGGCAGA
ACTCAGTTAAATCTTTGAAGAATATTTGTAGTTATCTTAGAAGATAGCATGGGAGGTGAGGATTCCAAAAACATTTTATTTTTAAAATAT
CCTGTGTAACACTTGGCTCTTGGTACCTGTGGGTTAGCATCAAGTTCTCCCCAGGGTAGAATTCAATCAGAGCTCCAGTTTGCATTTGGA
TGTGTAAATTACAGTAATCCCATTTCCCAAACCTAAAATCTGTTTTTCTCATCAGACTCTGAGTAACTGGTTGCTGTGTCATAACTTCAT
AGATGCAGGAGGCTCAGGTGATCTGTTTGAGGAGAGCACCCTAGGCAGCCTGCAGGGAATAACATACTGGCCGTTCTGACCTGTTGCCAG
CAGATACACAGGACATGGATGAAATTCCCGTTTCCTCTAGTTTCTTCCTGTAGTACTCCTCTTTTAGATCCTAAGTCTCTTACAAAAGCT
TTGAATACTGTGAAAATGTTTTACATTCCATTTCATTTGTGTTGTTTTTTTAACTGCATTTTACCAGATGTTTTGATGTTATCGCTTATG
TTAATAGTAATTCCCGTACGTGTTCATTTTATTTTCATGCTTTTTCAGCCATGTATCAATATTCACTTGACTAAAATCACTCAATTAATC

>74895_74895_6_RNF170-SFRP1_RNF170_chr8_42742871_ENST00000534961_SFRP1_chr8_41123008_ENST00000379845_length(amino acids)=168AA_BP=
MNFTLIFGHSRSRAALRVGPSTVAGDSGQPRGDSGASRRGRGPGGRRRRLPPPRRASAARATPRRPDPAVRGSAGPDRVGVAAARRTYLS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RNF170-SFRP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RNF170-SFRP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RNF170-SFRP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource