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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ROBO1-PSMD6 (FusionGDB2 ID:75261)

Fusion Gene Summary for ROBO1-PSMD6

check button Fusion gene summary
Fusion gene informationFusion gene name: ROBO1-PSMD6
Fusion gene ID: 75261
HgeneTgene
Gene symbol

ROBO1

PSMD6

Gene ID

6091

9861

Gene nameroundabout guidance receptor 1proteasome 26S subunit, non-ATPase 6
SynonymsDUTT1|SAX3Rpn7|S10|SGA-113M|p42A|p44S10
Cytomap

3p12.3

3p14.1

Type of geneprotein-codingprotein-coding
Descriptionroundabout homolog 1deleted in U twenty twentyroundabout, axon guidance receptor, homolog 126S proteasome non-ATPase regulatory subunit 6breast cancer-associated protein SGA-113Mphosphonoformate immuno-associated protein 4proteasome (prosome, macropain) 26S subunit, non-ATPase, 6proteasome regulatory particle subunit p44S10
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000464233, ENST00000436010, 
ENST00000467549, ENST00000495273, 
ENST00000466906, 		ENST00000295901, 
ENST00000394431, ENST00000482510, 
ENST00000492933, 
Fusion gene scores* DoF score18 X 16 X 7=20165 X 4 X 4=80
# samples 185
** MAII scorelog2(18/2016*10)=-3.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/80*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ROBO1 [Title/Abstract] AND PSMD6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointROBO1(78987751)-PSMD6(64008199), # samples:1
Anticipated loss of major functional domain due to fusion event.ROBO1-PSMD6 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
ROBO1-PSMD6 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ROBO1-PSMD6 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneROBO1

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

12504588

HgeneROBO1

GO:0021836

chemorepulsion involved in postnatal olfactory bulb interneuron migration

15207848

HgeneROBO1

GO:0050772

positive regulation of axonogenesis

12504588

HgeneROBO1

GO:0050925

negative regulation of negative chemotaxis

11748139


check buttonFusion gene breakpoints across ROBO1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PSMD6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-B0-5703-11AROBO1chr3

78987751

-PSMD6chr3

64008199

-


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Fusion Gene ORF analysis for ROBO1-PSMD6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000464233ENST00000295901ROBO1chr3

78987751

-PSMD6chr3

64008199

-
Frame-shiftENST00000464233ENST00000394431ROBO1chr3

78987751

-PSMD6chr3

64008199

-
Frame-shiftENST00000464233ENST00000482510ROBO1chr3

78987751

-PSMD6chr3

64008199

-
Frame-shiftENST00000464233ENST00000492933ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000436010ENST00000295901ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000436010ENST00000394431ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000436010ENST00000482510ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000436010ENST00000492933ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000467549ENST00000295901ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000467549ENST00000394431ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000467549ENST00000482510ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000467549ENST00000492933ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000495273ENST00000295901ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000495273ENST00000394431ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000495273ENST00000482510ROBO1chr3

78987751

-PSMD6chr3

64008199

-
In-frameENST00000495273ENST00000492933ROBO1chr3

78987751

-PSMD6chr3

64008199

-
intron-3CDSENST00000466906ENST00000295901ROBO1chr3

78987751

-PSMD6chr3

64008199

-
intron-3CDSENST00000466906ENST00000394431ROBO1chr3

78987751

-PSMD6chr3

64008199

-
intron-3CDSENST00000466906ENST00000482510ROBO1chr3

78987751

-PSMD6chr3

64008199

-
intron-3CDSENST00000466906ENST00000492933ROBO1chr3

78987751

-PSMD6chr3

64008199

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000436010ROBO1chr378987751-ENST00000295901PSMD6chr364008199-252413809982404468
ENST00000436010ROBO1chr378987751-ENST00000492933PSMD6chr364008199-251813809982404468
ENST00000436010ROBO1chr378987751-ENST00000394431PSMD6chr364008199-251813809982404468
ENST00000436010ROBO1chr378987751-ENST00000482510PSMD6chr364008199-248913809982404468
ENST00000495273ROBO1chr378987751-ENST00000295901PSMD6chr364008199-20809365541960468
ENST00000495273ROBO1chr378987751-ENST00000492933PSMD6chr364008199-20749365541960468
ENST00000495273ROBO1chr378987751-ENST00000394431PSMD6chr364008199-20749365541960468
ENST00000495273ROBO1chr378987751-ENST00000482510PSMD6chr364008199-20459365541960468
ENST00000467549ROBO1chr378987751-ENST00000295901PSMD6chr364008199-1609465831489468
ENST00000467549ROBO1chr378987751-ENST00000492933PSMD6chr364008199-1603465831489468
ENST00000467549ROBO1chr378987751-ENST00000394431PSMD6chr364008199-1603465831489468
ENST00000467549ROBO1chr378987751-ENST00000482510PSMD6chr364008199-1574465831489468

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000436010ENST00000295901ROBO1chr378987751-PSMD6chr364008199-0.0017259010.9982741
ENST00000436010ENST00000492933ROBO1chr378987751-PSMD6chr364008199-0.0017576190.9982424
ENST00000436010ENST00000394431ROBO1chr378987751-PSMD6chr364008199-0.0017576190.9982424
ENST00000436010ENST00000482510ROBO1chr378987751-PSMD6chr364008199-0.0019709170.99802905
ENST00000495273ENST00000295901ROBO1chr378987751-PSMD6chr364008199-0.0010854570.9989146
ENST00000495273ENST00000492933ROBO1chr378987751-PSMD6chr364008199-0.0011083840.99889165
ENST00000495273ENST00000394431ROBO1chr378987751-PSMD6chr364008199-0.0011083840.99889165
ENST00000495273ENST00000482510ROBO1chr378987751-PSMD6chr364008199-0.001263070.9987369
ENST00000467549ENST00000295901ROBO1chr378987751-PSMD6chr364008199-0.0007213720.9992786
ENST00000467549ENST00000492933ROBO1chr378987751-PSMD6chr364008199-0.0007335660.99926645
ENST00000467549ENST00000394431ROBO1chr378987751-PSMD6chr364008199-0.0007335660.99926645
ENST00000467549ENST00000482510ROBO1chr378987751-PSMD6chr364008199-0.0008378350.9991622

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Fusion Genomic Features for ROBO1-PSMD6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ROBO1-PSMD6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:78987751/chr3:64008199)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneROBO1chr3:78987751chr3:64008199ENST00000464233-43168_1641661652.0DomainNote=Ig-like C2-type 1
TgenePSMD6chr3:78987751chr3:64008199ENST0000029590108193_36148390.0DomainPCI
TgenePSMD6chr3:78987751chr3:64008199ENST0000039443108193_36110352.0DomainPCI

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneROBO1chr3:78987751chr3:64008199ENST00000436010-229170_2571271613.0DomainNote=Ig-like C2-type 2
HgeneROBO1chr3:78987751chr3:64008199ENST00000436010-229262_3461271613.0DomainNote=Ig-like C2-type 3
HgeneROBO1chr3:78987751chr3:64008199ENST00000436010-229351_4461271613.0DomainNote=Ig-like C2-type 4
HgeneROBO1chr3:78987751chr3:64008199ENST00000436010-229455_5411271613.0DomainNote=Ig-like C2-type 5
HgeneROBO1chr3:78987751chr3:64008199ENST00000436010-229563_6571271613.0DomainFibronectin type-III 1
HgeneROBO1chr3:78987751chr3:64008199ENST00000436010-229676_7731271613.0DomainFibronectin type-III 2
HgeneROBO1chr3:78987751chr3:64008199ENST00000436010-22968_1641271613.0DomainNote=Ig-like C2-type 1
HgeneROBO1chr3:78987751chr3:64008199ENST00000436010-229778_8741271613.0DomainFibronectin type-III 3
HgeneROBO1chr3:78987751chr3:64008199ENST00000464233-431170_2571661652.0DomainNote=Ig-like C2-type 2
HgeneROBO1chr3:78987751chr3:64008199ENST00000464233-431262_3461661652.0DomainNote=Ig-like C2-type 3
HgeneROBO1chr3:78987751chr3:64008199ENST00000464233-431351_4461661652.0DomainNote=Ig-like C2-type 4
HgeneROBO1chr3:78987751chr3:64008199ENST00000464233-431455_5411661652.0DomainNote=Ig-like C2-type 5
HgeneROBO1chr3:78987751chr3:64008199ENST00000464233-431563_6571661652.0DomainFibronectin type-III 1
HgeneROBO1chr3:78987751chr3:64008199ENST00000464233-431676_7731661652.0DomainFibronectin type-III 2
HgeneROBO1chr3:78987751chr3:64008199ENST00000464233-431778_8741661652.0DomainFibronectin type-III 3
HgeneROBO1chr3:78987751chr3:64008199ENST00000467549-229170_2571271552.0DomainNote=Ig-like C2-type 2
HgeneROBO1chr3:78987751chr3:64008199ENST00000467549-229262_3461271552.0DomainNote=Ig-like C2-type 3
HgeneROBO1chr3:78987751chr3:64008199ENST00000467549-229351_4461271552.0DomainNote=Ig-like C2-type 4
HgeneROBO1chr3:78987751chr3:64008199ENST00000467549-229455_5411271552.0DomainNote=Ig-like C2-type 5
HgeneROBO1chr3:78987751chr3:64008199ENST00000467549-229563_6571271552.0DomainFibronectin type-III 1
HgeneROBO1chr3:78987751chr3:64008199ENST00000467549-229676_7731271552.0DomainFibronectin type-III 2
HgeneROBO1chr3:78987751chr3:64008199ENST00000467549-22968_1641271552.0DomainNote=Ig-like C2-type 1
HgeneROBO1chr3:78987751chr3:64008199ENST00000467549-229778_8741271552.0DomainFibronectin type-III 3
HgeneROBO1chr3:78987751chr3:64008199ENST00000495273-229170_2571271607.0DomainNote=Ig-like C2-type 2
HgeneROBO1chr3:78987751chr3:64008199ENST00000495273-229262_3461271607.0DomainNote=Ig-like C2-type 3
HgeneROBO1chr3:78987751chr3:64008199ENST00000495273-229351_4461271607.0DomainNote=Ig-like C2-type 4
HgeneROBO1chr3:78987751chr3:64008199ENST00000495273-229455_5411271607.0DomainNote=Ig-like C2-type 5
HgeneROBO1chr3:78987751chr3:64008199ENST00000495273-229563_6571271607.0DomainFibronectin type-III 1
HgeneROBO1chr3:78987751chr3:64008199ENST00000495273-229676_7731271607.0DomainFibronectin type-III 2
HgeneROBO1chr3:78987751chr3:64008199ENST00000495273-22968_1641271607.0DomainNote=Ig-like C2-type 1
HgeneROBO1chr3:78987751chr3:64008199ENST00000495273-229778_8741271607.0DomainFibronectin type-III 3
HgeneROBO1chr3:78987751chr3:64008199ENST00000436010-22926_8971271613.0Topological domainExtracellular
HgeneROBO1chr3:78987751chr3:64008199ENST00000436010-229919_16511271613.0Topological domainCytoplasmic
HgeneROBO1chr3:78987751chr3:64008199ENST00000464233-43126_8971661652.0Topological domainExtracellular
HgeneROBO1chr3:78987751chr3:64008199ENST00000464233-431919_16511661652.0Topological domainCytoplasmic
HgeneROBO1chr3:78987751chr3:64008199ENST00000467549-22926_8971271552.0Topological domainExtracellular
HgeneROBO1chr3:78987751chr3:64008199ENST00000467549-229919_16511271552.0Topological domainCytoplasmic
HgeneROBO1chr3:78987751chr3:64008199ENST00000495273-22926_8971271607.0Topological domainExtracellular
HgeneROBO1chr3:78987751chr3:64008199ENST00000495273-229919_16511271607.0Topological domainCytoplasmic
HgeneROBO1chr3:78987751chr3:64008199ENST00000436010-229898_9181271613.0TransmembraneHelical
HgeneROBO1chr3:78987751chr3:64008199ENST00000464233-431898_9181661652.0TransmembraneHelical
HgeneROBO1chr3:78987751chr3:64008199ENST00000467549-229898_9181271552.0TransmembraneHelical
HgeneROBO1chr3:78987751chr3:64008199ENST00000495273-229898_9181271607.0TransmembraneHelical


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Fusion Gene Sequence for ROBO1-PSMD6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>75261_75261_1_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000436010_PSMD6_chr3_64008199_ENST00000295901_length(transcript)=2524nt_BP=1380nt
AATTGAGCTGGAGAGGAGGCAGCGTGAGAGCAGAAACTTCAGACGCCGCTGATCCGGGAGGAGCTGGGGTGAGCCGCGGCGGCCGTCTCT
CCCACCCGCAGCAGCATCCTCTCTGCCCTTCTCTGCCACCCCGGGGAGAGCCGGGAGCTGCCTCTTTACAGCTTCCACGAGCCAGGGGTG
CAGGCAGCTGCCCCCAGGAAGTTTGGGCTTCTGCGTAGTTTAGGGGTGCCTGCGAGCGCCCCAGAGGGCGAGGGGCCGAGGGCGATGTTG
GGCGCCGCGCGGGGCTGGGGGCGCCCAGAAGACGTGCGAGTGTCCGCGGTCCTGCTGCTGTCTCCAGTACCCTCCGCATCCCCCAAGTGA
TGGGAACAAGGGCCCGCCCAGGCAGCCGCTGTCGCCGCACCGCCCCCTCGCTCGCTCTCTGCGCGCGGAGTCACCCAGTCACACTCCCGG
CACCCCGAGCCCTTCCTCCGGAGCTGCTGCTTCTACTTTGGCTGCTATCGCCGCCGCCGCGGGTGGCCCGCTGCTGACTGGGCTCGCCGG
GAGACGGAGAAGCACTTTTTGGCCCTCCCTCAGCAGCTCTCACACCCCAACTTTGCCGCCGCCGCCGCGCCTGCCCTCGCAGCGGCGCTC
GGCCGCACATTGTGGGGGCGCACGCCGGGAGGCTCCGCAAGACCGTGGAGGCAGGAAACGGCACTACTGCGCTTCTGCCTCGGCTCTTTG
TTGTTCGCTTTGGATGGTTCTTGAAAGTGTCTGAGCCTCCTCGGAAATCCTGGGGCCGGAGAAGACAAACCTTGGAATTCTTCCTCTGCA
AAAGTCTCTGAGATACTGACAAGCGTCCGGAAAGGTCGACGAGTAATTGCCCTGAAAACTCTTGGCTAATTGACCCACGTTGCTTATATT
AAGCCTTTGTGTGTGGTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGATCCACC
CGAGGACAATGATTGCGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAGATTTTC
CACCTCGCATTGTTGAACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCCCCACAC
CCACTATTGAATGGTACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTGGATCTT
TATTTTTCTTACGTATAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAGAGGCTG
TGAGCCACAATGCATCGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACGTGGACC
TACTCAATAAAATGAAGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAGAGAGCG
AAATTCGCGATGCAATGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGACATATG
ACAAAACTGTGGCCCTGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCATCACAC
GAAACACAGAAAAGGCCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTTATTGTG
TGGCTATTCGTGATTTCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATAAAACAT
TTGTGACTTATACTGTCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTCTTGAAG
TGTTGCACAGTCTTCCAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGGTTGTGG
AACAGGAAATGAAAAAGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGCTGCTGG
AATCATATAGGTCATTAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGTTTATTG
CTGCCGGGAGACTACACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACCAAGAAA
CTATCAAGAAAGGAGATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAGGATTTG
CTTTAGAGATAATTATTTGGAATTTTTATAGCTTACTTCACAATGTGCCCAGGTCAGCTGTATAAAATAAATACTGCATTGTTGTTTCTT

>75261_75261_1_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000436010_PSMD6_chr3_64008199_ENST00000295901_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------
>75261_75261_2_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000436010_PSMD6_chr3_64008199_ENST00000394431_length(transcript)=2518nt_BP=1380nt
AATTGAGCTGGAGAGGAGGCAGCGTGAGAGCAGAAACTTCAGACGCCGCTGATCCGGGAGGAGCTGGGGTGAGCCGCGGCGGCCGTCTCT
CCCACCCGCAGCAGCATCCTCTCTGCCCTTCTCTGCCACCCCGGGGAGAGCCGGGAGCTGCCTCTTTACAGCTTCCACGAGCCAGGGGTG
CAGGCAGCTGCCCCCAGGAAGTTTGGGCTTCTGCGTAGTTTAGGGGTGCCTGCGAGCGCCCCAGAGGGCGAGGGGCCGAGGGCGATGTTG
GGCGCCGCGCGGGGCTGGGGGCGCCCAGAAGACGTGCGAGTGTCCGCGGTCCTGCTGCTGTCTCCAGTACCCTCCGCATCCCCCAAGTGA
TGGGAACAAGGGCCCGCCCAGGCAGCCGCTGTCGCCGCACCGCCCCCTCGCTCGCTCTCTGCGCGCGGAGTCACCCAGTCACACTCCCGG
CACCCCGAGCCCTTCCTCCGGAGCTGCTGCTTCTACTTTGGCTGCTATCGCCGCCGCCGCGGGTGGCCCGCTGCTGACTGGGCTCGCCGG
GAGACGGAGAAGCACTTTTTGGCCCTCCCTCAGCAGCTCTCACACCCCAACTTTGCCGCCGCCGCCGCGCCTGCCCTCGCAGCGGCGCTC
GGCCGCACATTGTGGGGGCGCACGCCGGGAGGCTCCGCAAGACCGTGGAGGCAGGAAACGGCACTACTGCGCTTCTGCCTCGGCTCTTTG
TTGTTCGCTTTGGATGGTTCTTGAAAGTGTCTGAGCCTCCTCGGAAATCCTGGGGCCGGAGAAGACAAACCTTGGAATTCTTCCTCTGCA
AAAGTCTCTGAGATACTGACAAGCGTCCGGAAAGGTCGACGAGTAATTGCCCTGAAAACTCTTGGCTAATTGACCCACGTTGCTTATATT
AAGCCTTTGTGTGTGGTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGATCCACC
CGAGGACAATGATTGCGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAGATTTTC
CACCTCGCATTGTTGAACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCCCCACAC
CCACTATTGAATGGTACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTGGATCTT
TATTTTTCTTACGTATAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAGAGGCTG
TGAGCCACAATGCATCGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACGTGGACC
TACTCAATAAAATGAAGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAGAGAGCG
AAATTCGCGATGCAATGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGACATATG
ACAAAACTGTGGCCCTGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCATCACAC
GAAACACAGAAAAGGCCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTTATTGTG
TGGCTATTCGTGATTTCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATAAAACAT
TTGTGACTTATACTGTCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTCTTGAAG
TGTTGCACAGTCTTCCAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGGTTGTGG
AACAGGAAATGAAAAAGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGCTGCTGG
AATCATATAGGTCATTAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGTTTATTG
CTGCCGGGAGACTACACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACCAAGAAA
CTATCAAGAAAGGAGATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAGGATTTG

>75261_75261_2_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000436010_PSMD6_chr3_64008199_ENST00000394431_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------
>75261_75261_3_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000436010_PSMD6_chr3_64008199_ENST00000482510_length(transcript)=2489nt_BP=1380nt
AATTGAGCTGGAGAGGAGGCAGCGTGAGAGCAGAAACTTCAGACGCCGCTGATCCGGGAGGAGCTGGGGTGAGCCGCGGCGGCCGTCTCT
CCCACCCGCAGCAGCATCCTCTCTGCCCTTCTCTGCCACCCCGGGGAGAGCCGGGAGCTGCCTCTTTACAGCTTCCACGAGCCAGGGGTG
CAGGCAGCTGCCCCCAGGAAGTTTGGGCTTCTGCGTAGTTTAGGGGTGCCTGCGAGCGCCCCAGAGGGCGAGGGGCCGAGGGCGATGTTG
GGCGCCGCGCGGGGCTGGGGGCGCCCAGAAGACGTGCGAGTGTCCGCGGTCCTGCTGCTGTCTCCAGTACCCTCCGCATCCCCCAAGTGA
TGGGAACAAGGGCCCGCCCAGGCAGCCGCTGTCGCCGCACCGCCCCCTCGCTCGCTCTCTGCGCGCGGAGTCACCCAGTCACACTCCCGG
CACCCCGAGCCCTTCCTCCGGAGCTGCTGCTTCTACTTTGGCTGCTATCGCCGCCGCCGCGGGTGGCCCGCTGCTGACTGGGCTCGCCGG
GAGACGGAGAAGCACTTTTTGGCCCTCCCTCAGCAGCTCTCACACCCCAACTTTGCCGCCGCCGCCGCGCCTGCCCTCGCAGCGGCGCTC
GGCCGCACATTGTGGGGGCGCACGCCGGGAGGCTCCGCAAGACCGTGGAGGCAGGAAACGGCACTACTGCGCTTCTGCCTCGGCTCTTTG
TTGTTCGCTTTGGATGGTTCTTGAAAGTGTCTGAGCCTCCTCGGAAATCCTGGGGCCGGAGAAGACAAACCTTGGAATTCTTCCTCTGCA
AAAGTCTCTGAGATACTGACAAGCGTCCGGAAAGGTCGACGAGTAATTGCCCTGAAAACTCTTGGCTAATTGACCCACGTTGCTTATATT
AAGCCTTTGTGTGTGGTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGATCCACC
CGAGGACAATGATTGCGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAGATTTTC
CACCTCGCATTGTTGAACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCCCCACAC
CCACTATTGAATGGTACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTGGATCTT
TATTTTTCTTACGTATAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAGAGGCTG
TGAGCCACAATGCATCGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACGTGGACC
TACTCAATAAAATGAAGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAGAGAGCG
AAATTCGCGATGCAATGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGACATATG
ACAAAACTGTGGCCCTGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCATCACAC
GAAACACAGAAAAGGCCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTTATTGTG
TGGCTATTCGTGATTTCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATAAAACAT
TTGTGACTTATACTGTCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTCTTGAAG
TGTTGCACAGTCTTCCAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGGTTGTGG
AACAGGAAATGAAAAAGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGCTGCTGG
AATCATATAGGTCATTAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGTTTATTG
CTGCCGGGAGACTACACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACCAAGAAA
CTATCAAGAAAGGAGATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAGGATTTG

>75261_75261_3_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000436010_PSMD6_chr3_64008199_ENST00000482510_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------
>75261_75261_4_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000436010_PSMD6_chr3_64008199_ENST00000492933_length(transcript)=2518nt_BP=1380nt
AATTGAGCTGGAGAGGAGGCAGCGTGAGAGCAGAAACTTCAGACGCCGCTGATCCGGGAGGAGCTGGGGTGAGCCGCGGCGGCCGTCTCT
CCCACCCGCAGCAGCATCCTCTCTGCCCTTCTCTGCCACCCCGGGGAGAGCCGGGAGCTGCCTCTTTACAGCTTCCACGAGCCAGGGGTG
CAGGCAGCTGCCCCCAGGAAGTTTGGGCTTCTGCGTAGTTTAGGGGTGCCTGCGAGCGCCCCAGAGGGCGAGGGGCCGAGGGCGATGTTG
GGCGCCGCGCGGGGCTGGGGGCGCCCAGAAGACGTGCGAGTGTCCGCGGTCCTGCTGCTGTCTCCAGTACCCTCCGCATCCCCCAAGTGA
TGGGAACAAGGGCCCGCCCAGGCAGCCGCTGTCGCCGCACCGCCCCCTCGCTCGCTCTCTGCGCGCGGAGTCACCCAGTCACACTCCCGG
CACCCCGAGCCCTTCCTCCGGAGCTGCTGCTTCTACTTTGGCTGCTATCGCCGCCGCCGCGGGTGGCCCGCTGCTGACTGGGCTCGCCGG
GAGACGGAGAAGCACTTTTTGGCCCTCCCTCAGCAGCTCTCACACCCCAACTTTGCCGCCGCCGCCGCGCCTGCCCTCGCAGCGGCGCTC
GGCCGCACATTGTGGGGGCGCACGCCGGGAGGCTCCGCAAGACCGTGGAGGCAGGAAACGGCACTACTGCGCTTCTGCCTCGGCTCTTTG
TTGTTCGCTTTGGATGGTTCTTGAAAGTGTCTGAGCCTCCTCGGAAATCCTGGGGCCGGAGAAGACAAACCTTGGAATTCTTCCTCTGCA
AAAGTCTCTGAGATACTGACAAGCGTCCGGAAAGGTCGACGAGTAATTGCCCTGAAAACTCTTGGCTAATTGACCCACGTTGCTTATATT
AAGCCTTTGTGTGTGGTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGATCCACC
CGAGGACAATGATTGCGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAGATTTTC
CACCTCGCATTGTTGAACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCCCCACAC
CCACTATTGAATGGTACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTGGATCTT
TATTTTTCTTACGTATAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAGAGGCTG
TGAGCCACAATGCATCGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACGTGGACC
TACTCAATAAAATGAAGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAGAGAGCG
AAATTCGCGATGCAATGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGACATATG
ACAAAACTGTGGCCCTGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCATCACAC
GAAACACAGAAAAGGCCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTTATTGTG
TGGCTATTCGTGATTTCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATAAAACAT
TTGTGACTTATACTGTCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTCTTGAAG
TGTTGCACAGTCTTCCAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGGTTGTGG
AACAGGAAATGAAAAAGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGCTGCTGG
AATCATATAGGTCATTAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGTTTATTG
CTGCCGGGAGACTACACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACCAAGAAA
CTATCAAGAAAGGAGATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAGGATTTG

>75261_75261_4_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000436010_PSMD6_chr3_64008199_ENST00000492933_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------
>75261_75261_5_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000467549_PSMD6_chr3_64008199_ENST00000295901_length(transcript)=1609nt_BP=465nt
GTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGATCCACCCGAGGACAATGATTG
CGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAGATTTTCCACCTCGCATTGTTG
AACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCCCCACACCCACTATTGAATGGT
ACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTGGATCTTTATTTTTCTTACGTA
TAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAGAGGCTGTGAGCCACAATGCAT
CGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACGTGGACCTACTCAATAAAATGA
AGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAGAGAGCGAAATTCGCGATGCAA
TGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGACATATGACAAAACTGTGGCCC
TGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCATCACACGAAACACAGAAAAGG
CCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTTATTGTGTGGCTATTCGTGATT
TCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATAAAACATTTGTGACTTATACTG
TCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTCTTGAAGTGTTGCACAGTCTTC
CAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGGTTGTGGAACAGGAAATGAAAA
AGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGCTGCTGGAATCATATAGGTCAT
TAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGTTTATTGCTGCCGGGAGACTAC
ACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACCAAGAAACTATCAAGAAAGGAG
ATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAGGATTTGCTTTAGAGATAATTA

>75261_75261_5_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000467549_PSMD6_chr3_64008199_ENST00000295901_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------
>75261_75261_6_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000467549_PSMD6_chr3_64008199_ENST00000394431_length(transcript)=1603nt_BP=465nt
GTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGATCCACCCGAGGACAATGATTG
CGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAGATTTTCCACCTCGCATTGTTG
AACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCCCCACACCCACTATTGAATGGT
ACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTGGATCTTTATTTTTCTTACGTA
TAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAGAGGCTGTGAGCCACAATGCAT
CGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACGTGGACCTACTCAATAAAATGA
AGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAGAGAGCGAAATTCGCGATGCAA
TGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGACATATGACAAAACTGTGGCCC
TGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCATCACACGAAACACAGAAAAGG
CCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTTATTGTGTGGCTATTCGTGATT
TCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATAAAACATTTGTGACTTATACTG
TCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTCTTGAAGTGTTGCACAGTCTTC
CAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGGTTGTGGAACAGGAAATGAAAA
AGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGCTGCTGGAATCATATAGGTCAT
TAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGTTTATTGCTGCCGGGAGACTAC
ACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACCAAGAAACTATCAAGAAAGGAG
ATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAGGATTTGCTTTAGAGATAATTA

>75261_75261_6_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000467549_PSMD6_chr3_64008199_ENST00000394431_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------
>75261_75261_7_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000467549_PSMD6_chr3_64008199_ENST00000482510_length(transcript)=1574nt_BP=465nt
GTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGATCCACCCGAGGACAATGATTG
CGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAGATTTTCCACCTCGCATTGTTG
AACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCCCCACACCCACTATTGAATGGT
ACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTGGATCTTTATTTTTCTTACGTA
TAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAGAGGCTGTGAGCCACAATGCAT
CGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACGTGGACCTACTCAATAAAATGA
AGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAGAGAGCGAAATTCGCGATGCAA
TGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGACATATGACAAAACTGTGGCCC
TGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCATCACACGAAACACAGAAAAGG
CCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTTATTGTGTGGCTATTCGTGATT
TCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATAAAACATTTGTGACTTATACTG
TCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTCTTGAAGTGTTGCACAGTCTTC
CAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGGTTGTGGAACAGGAAATGAAAA
AGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGCTGCTGGAATCATATAGGTCAT
TAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGTTTATTGCTGCCGGGAGACTAC
ACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACCAAGAAACTATCAAGAAAGGAG
ATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAGGATTTGCTTTAGAGATAATTA

>75261_75261_7_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000467549_PSMD6_chr3_64008199_ENST00000482510_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------
>75261_75261_8_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000467549_PSMD6_chr3_64008199_ENST00000492933_length(transcript)=1603nt_BP=465nt
GTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGATCCACCCGAGGACAATGATTG
CGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAGATTTTCCACCTCGCATTGTTG
AACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCCCCACACCCACTATTGAATGGT
ACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTGGATCTTTATTTTTCTTACGTA
TAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAGAGGCTGTGAGCCACAATGCAT
CGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACGTGGACCTACTCAATAAAATGA
AGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAGAGAGCGAAATTCGCGATGCAA
TGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGACATATGACAAAACTGTGGCCC
TGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCATCACACGAAACACAGAAAAGG
CCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTTATTGTGTGGCTATTCGTGATT
TCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATAAAACATTTGTGACTTATACTG
TCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTCTTGAAGTGTTGCACAGTCTTC
CAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGGTTGTGGAACAGGAAATGAAAA
AGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGCTGCTGGAATCATATAGGTCAT
TAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGTTTATTGCTGCCGGGAGACTAC
ACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACCAAGAAACTATCAAGAAAGGAG
ATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAGGATTTGCTTTAGAGATAATTA

>75261_75261_8_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000467549_PSMD6_chr3_64008199_ENST00000492933_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------
>75261_75261_9_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000495273_PSMD6_chr3_64008199_ENST00000295901_length(transcript)=2080nt_BP=936nt
TCCCGGCACCCCGAGCCCTTCCTCCGGAGCTGCTGCTTCTACTTTGGCTGCTATCGCCGCCGCCGCGGGTGGCCCGCTGCTGACTGGGCT
CGCCGGGAGACGGAGAAGCACTTTTTGGCCCTCCCTCAGCAGCTCTCACACCCCAACTTTGCCGCCGCCGCCGCGCCTGCCCTCGCAGCG
GCGCTCGGCCGCACATTGTGGGGGCGCACGCCGGGAGGCTCCGCAAGACCGTGGAGGCAGGAAACGGCACTACTGCGCTTCTGCCTCGGC
TCTTTGTTGTTCGCTTTGGATGGTTCTTGAAAGTGTCTGAGCCTCCTCGGAAATCCTGGGGCCGGAGAAGACAAACCTTGGAATTCTTCC
TCTGCAAAAGTCTCTGAGATACTGACAAGCGTCCGGAAAGGTCGACGAGTAATTGCCCTGAAAACTCTTGGCTAATTGACCCACGTTGCT
TATATTAAGCCTTTGTGTGTGGTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGA
TCCACCCGAGGACAATGATTGCGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAG
ATTTTCCACCTCGCATTGTTGAACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCC
CCACACCCACTATTGAATGGTACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTG
GATCTTTATTTTTCTTACGTATAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAG
AGGCTGTGAGCCACAATGCATCGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACG
TGGACCTACTCAATAAAATGAAGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAG
AGAGCGAAATTCGCGATGCAATGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGA
CATATGACAAAACTGTGGCCCTGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCA
TCACACGAAACACAGAAAAGGCCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTT
ATTGTGTGGCTATTCGTGATTTCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATA
AAACATTTGTGACTTATACTGTCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTC
TTGAAGTGTTGCACAGTCTTCCAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGG
TTGTGGAACAGGAAATGAAAAAGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGC
TGCTGGAATCATATAGGTCATTAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGT
TTATTGCTGCCGGGAGACTACACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACC
AAGAAACTATCAAGAAAGGAGATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAG
GATTTGCTTTAGAGATAATTATTTGGAATTTTTATAGCTTACTTCACAATGTGCCCAGGTCAGCTGTATAAAATAAATACTGCATTGTTG

>75261_75261_9_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000495273_PSMD6_chr3_64008199_ENST00000295901_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------
>75261_75261_10_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000495273_PSMD6_chr3_64008199_ENST00000394431_length(transcript)=2074nt_BP=936nt
TCCCGGCACCCCGAGCCCTTCCTCCGGAGCTGCTGCTTCTACTTTGGCTGCTATCGCCGCCGCCGCGGGTGGCCCGCTGCTGACTGGGCT
CGCCGGGAGACGGAGAAGCACTTTTTGGCCCTCCCTCAGCAGCTCTCACACCCCAACTTTGCCGCCGCCGCCGCGCCTGCCCTCGCAGCG
GCGCTCGGCCGCACATTGTGGGGGCGCACGCCGGGAGGCTCCGCAAGACCGTGGAGGCAGGAAACGGCACTACTGCGCTTCTGCCTCGGC
TCTTTGTTGTTCGCTTTGGATGGTTCTTGAAAGTGTCTGAGCCTCCTCGGAAATCCTGGGGCCGGAGAAGACAAACCTTGGAATTCTTCC
TCTGCAAAAGTCTCTGAGATACTGACAAGCGTCCGGAAAGGTCGACGAGTAATTGCCCTGAAAACTCTTGGCTAATTGACCCACGTTGCT
TATATTAAGCCTTTGTGTGTGGTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGA
TCCACCCGAGGACAATGATTGCGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAG
ATTTTCCACCTCGCATTGTTGAACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCC
CCACACCCACTATTGAATGGTACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTG
GATCTTTATTTTTCTTACGTATAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAG
AGGCTGTGAGCCACAATGCATCGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACG
TGGACCTACTCAATAAAATGAAGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAG
AGAGCGAAATTCGCGATGCAATGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGA
CATATGACAAAACTGTGGCCCTGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCA
TCACACGAAACACAGAAAAGGCCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTT
ATTGTGTGGCTATTCGTGATTTCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATA
AAACATTTGTGACTTATACTGTCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTC
TTGAAGTGTTGCACAGTCTTCCAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGG
TTGTGGAACAGGAAATGAAAAAGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGC
TGCTGGAATCATATAGGTCATTAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGT
TTATTGCTGCCGGGAGACTACACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACC
AAGAAACTATCAAGAAAGGAGATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAG
GATTTGCTTTAGAGATAATTATTTGGAATTTTTATAGCTTACTTCACAATGTGCCCAGGTCAGCTGTATAAAATAAATACTGCATTGTTG

>75261_75261_10_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000495273_PSMD6_chr3_64008199_ENST00000394431_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------
>75261_75261_11_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000495273_PSMD6_chr3_64008199_ENST00000482510_length(transcript)=2045nt_BP=936nt
TCCCGGCACCCCGAGCCCTTCCTCCGGAGCTGCTGCTTCTACTTTGGCTGCTATCGCCGCCGCCGCGGGTGGCCCGCTGCTGACTGGGCT
CGCCGGGAGACGGAGAAGCACTTTTTGGCCCTCCCTCAGCAGCTCTCACACCCCAACTTTGCCGCCGCCGCCGCGCCTGCCCTCGCAGCG
GCGCTCGGCCGCACATTGTGGGGGCGCACGCCGGGAGGCTCCGCAAGACCGTGGAGGCAGGAAACGGCACTACTGCGCTTCTGCCTCGGC
TCTTTGTTGTTCGCTTTGGATGGTTCTTGAAAGTGTCTGAGCCTCCTCGGAAATCCTGGGGCCGGAGAAGACAAACCTTGGAATTCTTCC
TCTGCAAAAGTCTCTGAGATACTGACAAGCGTCCGGAAAGGTCGACGAGTAATTGCCCTGAAAACTCTTGGCTAATTGACCCACGTTGCT
TATATTAAGCCTTTGTGTGTGGTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGA
TCCACCCGAGGACAATGATTGCGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAG
ATTTTCCACCTCGCATTGTTGAACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCC
CCACACCCACTATTGAATGGTACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTG
GATCTTTATTTTTCTTACGTATAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAG
AGGCTGTGAGCCACAATGCATCGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACG
TGGACCTACTCAATAAAATGAAGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAG
AGAGCGAAATTCGCGATGCAATGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGA
CATATGACAAAACTGTGGCCCTGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCA
TCACACGAAACACAGAAAAGGCCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTT
ATTGTGTGGCTATTCGTGATTTCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATA
AAACATTTGTGACTTATACTGTCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTC
TTGAAGTGTTGCACAGTCTTCCAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGG
TTGTGGAACAGGAAATGAAAAAGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGC
TGCTGGAATCATATAGGTCATTAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGT
TTATTGCTGCCGGGAGACTACACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACC
AAGAAACTATCAAGAAAGGAGATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAG

>75261_75261_11_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000495273_PSMD6_chr3_64008199_ENST00000482510_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------
>75261_75261_12_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000495273_PSMD6_chr3_64008199_ENST00000492933_length(transcript)=2074nt_BP=936nt
TCCCGGCACCCCGAGCCCTTCCTCCGGAGCTGCTGCTTCTACTTTGGCTGCTATCGCCGCCGCCGCGGGTGGCCCGCTGCTGACTGGGCT
CGCCGGGAGACGGAGAAGCACTTTTTGGCCCTCCCTCAGCAGCTCTCACACCCCAACTTTGCCGCCGCCGCCGCGCCTGCCCTCGCAGCG
GCGCTCGGCCGCACATTGTGGGGGCGCACGCCGGGAGGCTCCGCAAGACCGTGGAGGCAGGAAACGGCACTACTGCGCTTCTGCCTCGGC
TCTTTGTTGTTCGCTTTGGATGGTTCTTGAAAGTGTCTGAGCCTCCTCGGAAATCCTGGGGCCGGAGAAGACAAACCTTGGAATTCTTCC
TCTGCAAAAGTCTCTGAGATACTGACAAGCGTCCGGAAAGGTCGACGAGTAATTGCCCTGAAAACTCTTGGCTAATTGACCCACGTTGCT
TATATTAAGCCTTTGTGTGTGGTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCTCTTGGCATGAGACTGTATACAGGA
TCCACCCGAGGACAATGATTGCGGAGCCCGCTCACTTTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAG
ATTTTCCACCTCGCATTGTTGAACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTTTGAACTGCAAAGCTGAAGGCCGCC
CCACACCCACTATTGAATGGTACAAAGGGGGAGAGAGAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTG
GATCTTTATTTTTCTTACGTATAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCTGTGTAGCAAGGAATTACCTTGGAG
AGGCTGTGAGCCACAATGCATCGCTGGAAGTAGCCAACATGGCTCCTTACTATGAAGCCTTGTGCAAATCCCTCGACTGGCAGATAGACG
TGGACCTACTCAATAAAATGAAGAAGGCAAATGAAGATGAGTTGAAGCGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAATCTAGGAG
AGAGCGAAATTCGCGATGCAATGATGGCAAAGGCCGAGTACCTCTGCCGGATAGGTGACAAAGAGGGAGCTCTGACAGCCTTTCGCAAGA
CATATGACAAAACTGTGGCCCTGGGTCACCGATTGGATATTGTATTCTATCTCCTTAGGATTGGCTTATTTTATATGGATAATGATCTCA
TCACACGAAACACAGAAAAGGCCAAAAGCTTAATAGAAGAAGGAGGAGACTGGGACAGGAGAAACCGCCTAAAAGTGTATCAGGGTCTTT
ATTGTGTGGCTATTCGTGATTTCAAACAGGCAGCTGAACTCTTCCTTGACACTGTTTCAACATTTACATCCTATGAACTCATGGATTATA
AAACATTTGTGACTTATACTGTCTATGTCAGTATGATTGCCTTAGAAAGACCAGATCTCAGGGAAAAGGTCATTAAAGGAGCAGAGATTC
TTGAAGTGTTGCACAGTCTTCCAGCAGTTCGGCAGTATCTGTTTTCACTCTATGAATGCCGTTACTCTGTTTTCTTCCAATCATTAGCGG
TTGTGGAACAGGAAATGAAAAAGGACTGGCTTTTTGCCCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCATGCATACAGTCAGC
TGCTGGAATCATATAGGTCATTAACCCTTGGCTATATGGCAGAAGCGTTTGGTGTTGGTGTGGAATTCATTGATCAGGAACTGTCCAGGT
TTATTGCTGCCGGGAGACTACACTGCAAAATAGATAAAGTGAATGAAATAGTAGAAACCAACAGACCTGATAGCAAGAACTGGCAGTACC
AAGAAACTATCAAGAAAGGAGATCTGCTACTAAACAGAGTTCAAAAACTTTCCAGAGTAATTAATATGTAAAGCCATGTAACTAACAAAG
GATTTGCTTTAGAGATAATTATTTGGAATTTTTATAGCTTACTTCACAATGTGCCCAGGTCAGCTGTATAAAATAAATACTGCATTGTTG

>75261_75261_12_ROBO1-PSMD6_ROBO1_chr3_78987751_ENST00000495273_PSMD6_chr3_64008199_ENST00000492933_length(amino acids)=468AA_BP=128
MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF
LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVANMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIR
DAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAI
RDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQE
MKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ROBO1-PSMD6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ROBO1-PSMD6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ROBO1-PSMD6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource