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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ROCK2-MEIS1 (FusionGDB2 ID:75331)

Fusion Gene Summary for ROCK2-MEIS1

check button Fusion gene summary
Fusion gene informationFusion gene name: ROCK2-MEIS1
Fusion gene ID: 75331
HgeneTgene
Gene symbol

ROCK2

MEIS1

Gene ID

9475

4211

Gene nameRho associated coiled-coil containing protein kinase 2Meis homeobox 1
SynonymsROCK-II-
Cytomap

2p25.1

2p14

Type of geneprotein-codingprotein-coding
Descriptionrho-associated protein kinase 2p164 ROCK-2rho-associated, coiled-coil-containing protein kinase IIhomeobox protein Meis1Meis1, myeloid ecotropic viral integration site 1 homologWUGSC:H_NH0444B04.1leukemogenic homolog protein
Modification date2020032920200313
UniProtAcc.

O00470

Ensembl transtripts involved in fusion geneENST00000315872, ENST00000401753, 
ENST00000462366, 		ENST00000409517, 
ENST00000272369, ENST00000398506, 
ENST00000407092, ENST00000444274, 
ENST00000488550, ENST00000495021, 
ENST00000560281, 
Fusion gene scores* DoF score16 X 11 X 9=158411 X 10 X 4=440
# samples 1713
** MAII scorelog2(17/1584*10)=-3.21996568394191
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/440*10)=-1.7589919004962
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ROCK2 [Title/Abstract] AND MEIS1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointROCK2(11484122)-MEIS1(66775075), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneROCK2

GO:0006468

protein phosphorylation

18559669


check buttonFusion gene breakpoints across ROCK2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MEIS1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-29-1691-01AROCK2chr2

11484122

-MEIS1chr2

66775075

+
ChimerDB4OVTCGA-29-1691ROCK2chr2

11484121

-MEIS1chr2

66775074

+


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Fusion Gene ORF analysis for ROCK2-MEIS1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000315872ENST00000409517ROCK2chr2

11484122

-MEIS1chr2

66775075

+
5CDS-3UTRENST00000315872ENST00000409517ROCK2chr2

11484121

-MEIS1chr2

66775074

+
In-frameENST00000315872ENST00000272369ROCK2chr2

11484122

-MEIS1chr2

66775075

+
In-frameENST00000315872ENST00000272369ROCK2chr2

11484121

-MEIS1chr2

66775074

+
In-frameENST00000315872ENST00000398506ROCK2chr2

11484122

-MEIS1chr2

66775075

+
In-frameENST00000315872ENST00000398506ROCK2chr2

11484121

-MEIS1chr2

66775074

+
In-frameENST00000315872ENST00000407092ROCK2chr2

11484122

-MEIS1chr2

66775075

+
In-frameENST00000315872ENST00000407092ROCK2chr2

11484121

-MEIS1chr2

66775074

+
In-frameENST00000315872ENST00000444274ROCK2chr2

11484122

-MEIS1chr2

66775075

+
In-frameENST00000315872ENST00000444274ROCK2chr2

11484121

-MEIS1chr2

66775074

+
In-frameENST00000315872ENST00000488550ROCK2chr2

11484122

-MEIS1chr2

66775075

+
In-frameENST00000315872ENST00000488550ROCK2chr2

11484121

-MEIS1chr2

66775074

+
In-frameENST00000315872ENST00000495021ROCK2chr2

11484122

-MEIS1chr2

66775075

+
In-frameENST00000315872ENST00000495021ROCK2chr2

11484121

-MEIS1chr2

66775074

+
In-frameENST00000315872ENST00000560281ROCK2chr2

11484122

-MEIS1chr2

66775075

+
In-frameENST00000315872ENST00000560281ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000401753ENST00000272369ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000401753ENST00000272369ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000401753ENST00000398506ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000401753ENST00000398506ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000401753ENST00000407092ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000401753ENST00000407092ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000401753ENST00000444274ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000401753ENST00000444274ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000401753ENST00000488550ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000401753ENST00000488550ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000401753ENST00000495021ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000401753ENST00000495021ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000401753ENST00000560281ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000401753ENST00000560281ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000462366ENST00000272369ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000462366ENST00000272369ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000462366ENST00000398506ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000462366ENST00000398506ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000462366ENST00000407092ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000462366ENST00000407092ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000462366ENST00000444274ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000462366ENST00000444274ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000462366ENST00000488550ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000462366ENST00000488550ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000462366ENST00000495021ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000462366ENST00000495021ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3CDSENST00000462366ENST00000560281ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3CDSENST00000462366ENST00000560281ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3UTRENST00000401753ENST00000409517ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3UTRENST00000401753ENST00000409517ROCK2chr2

11484121

-MEIS1chr2

66775074

+
intron-3UTRENST00000462366ENST00000409517ROCK2chr2

11484122

-MEIS1chr2

66775075

+
intron-3UTRENST00000462366ENST00000409517ROCK2chr2

11484121

-MEIS1chr2

66775074

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000315872ROCK2chr211484122-ENST00000560281MEIS1chr266775075+1751590449814121
ENST00000315872ROCK2chr211484122-ENST00000407092MEIS1chr266775075+23295904491099216
ENST00000315872ROCK2chr211484122-ENST00000272369MEIS1chr266775075+3536590859386157
ENST00000315872ROCK2chr211484122-ENST00000488550MEIS1chr266775075+451459031633588141
ENST00000315872ROCK2chr211484122-ENST00000398506MEIS1chr266775075+20295904491099216
ENST00000315872ROCK2chr211484122-ENST00000444274MEIS1chr266775075+14295904491099216
ENST00000315872ROCK2chr211484122-ENST00000495021MEIS1chr266775075+15035905150172
ENST00000315872ROCK2chr211484121-ENST00000560281MEIS1chr266775074+1751590449814121
ENST00000315872ROCK2chr211484121-ENST00000407092MEIS1chr266775074+23295904491099216
ENST00000315872ROCK2chr211484121-ENST00000272369MEIS1chr266775074+3536590859386157
ENST00000315872ROCK2chr211484121-ENST00000488550MEIS1chr266775074+451459031633588141
ENST00000315872ROCK2chr211484121-ENST00000398506MEIS1chr266775074+20295904491099216
ENST00000315872ROCK2chr211484121-ENST00000444274MEIS1chr266775074+14295904491099216
ENST00000315872ROCK2chr211484121-ENST00000495021MEIS1chr266775074+15035905150172

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000315872ENST00000560281ROCK2chr211484122-MEIS1chr266775075+0.30923970.69076025
ENST00000315872ENST00000407092ROCK2chr211484122-MEIS1chr266775075+0.0102316150.9897684
ENST00000315872ENST00000272369ROCK2chr211484122-MEIS1chr266775075+0.0182511680.9817488
ENST00000315872ENST00000488550ROCK2chr211484122-MEIS1chr266775075+0.122936650.8770634
ENST00000315872ENST00000398506ROCK2chr211484122-MEIS1chr266775075+0.0101905440.9898094
ENST00000315872ENST00000444274ROCK2chr211484122-MEIS1chr266775075+0.0199531340.9800468
ENST00000315872ENST00000495021ROCK2chr211484122-MEIS1chr266775075+0.0308211260.9691789
ENST00000315872ENST00000560281ROCK2chr211484121-MEIS1chr266775074+0.30923970.69076025
ENST00000315872ENST00000407092ROCK2chr211484121-MEIS1chr266775074+0.0102316150.9897684
ENST00000315872ENST00000272369ROCK2chr211484121-MEIS1chr266775074+0.0182511680.9817488
ENST00000315872ENST00000488550ROCK2chr211484121-MEIS1chr266775074+0.122936650.8770634
ENST00000315872ENST00000398506ROCK2chr211484121-MEIS1chr266775074+0.0101905440.9898094
ENST00000315872ENST00000444274ROCK2chr211484121-MEIS1chr266775074+0.0199531340.9800468
ENST00000315872ENST00000495021ROCK2chr211484121-MEIS1chr266775074+0.0308211260.9691789

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Fusion Genomic Features for ROCK2-MEIS1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ROCK2chr211484121-MEIS1chr266775074+1.27E-060.9999987
ROCK2chr211484121-MEIS1chr266775074+1.27E-060.9999987
ROCK2chr211484121-MEIS1chr266775074+1.27E-060.9999987
ROCK2chr211484121-MEIS1chr266775074+1.27E-060.9999987

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ROCK2-MEIS1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:11484122/chr2:66775075)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MEIS1

O00470

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias. {ECO:0000269|PubMed:12609849}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMEIS1chr2:11484121chr2:66775074ENST00000272369713335_3902961109.3333333333333RegionRequired for transcriptional activation
TgeneMEIS1chr2:11484121chr2:66775074ENST00000398506611335_390294464.0RegionRequired for transcriptional activation
TgeneMEIS1chr2:11484122chr2:66775075ENST00000272369713335_3902961109.3333333333333RegionRequired for transcriptional activation
TgeneMEIS1chr2:11484122chr2:66775075ENST00000398506611335_390294464.0RegionRequired for transcriptional activation

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneROCK2chr2:11484121chr2:66775074ENST00000315872-1331053_1131471389.0Coiled coilOntology_term=ECO:0000255
HgeneROCK2chr2:11484121chr2:66775074ENST00000315872-133429_1024471389.0Coiled coilOntology_term=ECO:0000255
HgeneROCK2chr2:11484122chr2:66775075ENST00000315872-1331053_1131471389.0Coiled coilOntology_term=ECO:0000255
HgeneROCK2chr2:11484122chr2:66775075ENST00000315872-133429_1024471389.0Coiled coilOntology_term=ECO:0000255
HgeneROCK2chr2:11484121chr2:66775074ENST00000315872-1331150_1349471389.0DomainPH
HgeneROCK2chr2:11484121chr2:66775074ENST00000315872-133357_425471389.0DomainAGC-kinase C-terminal
HgeneROCK2chr2:11484121chr2:66775074ENST00000315872-133497_573471389.0DomainREM-1
HgeneROCK2chr2:11484121chr2:66775074ENST00000315872-13392_354471389.0DomainProtein kinase
HgeneROCK2chr2:11484122chr2:66775075ENST00000315872-1331150_1349471389.0DomainPH
HgeneROCK2chr2:11484122chr2:66775075ENST00000315872-133357_425471389.0DomainAGC-kinase C-terminal
HgeneROCK2chr2:11484122chr2:66775075ENST00000315872-133497_573471389.0DomainREM-1
HgeneROCK2chr2:11484122chr2:66775075ENST00000315872-13392_354471389.0DomainProtein kinase
HgeneROCK2chr2:11484121chr2:66775074ENST00000315872-13398_106471389.0Nucleotide bindingATP
HgeneROCK2chr2:11484122chr2:66775075ENST00000315872-13398_106471389.0Nucleotide bindingATP
HgeneROCK2chr2:11484121chr2:66775074ENST00000315872-133979_1047471389.0RegionRHOA binding
HgeneROCK2chr2:11484122chr2:66775075ENST00000315872-133979_1047471389.0RegionRHOA binding
HgeneROCK2chr2:11484121chr2:66775074ENST00000315872-1331260_1315471389.0Zinc fingerPhorbol-ester/DAG-type
HgeneROCK2chr2:11484122chr2:66775075ENST00000315872-1331260_1315471389.0Zinc fingerPhorbol-ester/DAG-type
TgeneMEIS1chr2:11484121chr2:66775074ENST00000272369713194_2402961109.3333333333333Compositional biasNote=Ser/Thr-rich
TgeneMEIS1chr2:11484121chr2:66775074ENST00000272369713242_2692961109.3333333333333Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMEIS1chr2:11484121chr2:66775074ENST00000272369713262_2692961109.3333333333333Compositional biasNote=Poly-Asp
TgeneMEIS1chr2:11484121chr2:66775074ENST00000398506611194_240294464.0Compositional biasNote=Ser/Thr-rich
TgeneMEIS1chr2:11484121chr2:66775074ENST00000398506611242_269294464.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMEIS1chr2:11484121chr2:66775074ENST00000398506611262_269294464.0Compositional biasNote=Poly-Asp
TgeneMEIS1chr2:11484122chr2:66775075ENST00000272369713194_2402961109.3333333333333Compositional biasNote=Ser/Thr-rich
TgeneMEIS1chr2:11484122chr2:66775075ENST00000272369713242_2692961109.3333333333333Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMEIS1chr2:11484122chr2:66775075ENST00000272369713262_2692961109.3333333333333Compositional biasNote=Poly-Asp
TgeneMEIS1chr2:11484122chr2:66775075ENST00000398506611194_240294464.0Compositional biasNote=Ser/Thr-rich
TgeneMEIS1chr2:11484122chr2:66775075ENST00000398506611242_269294464.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMEIS1chr2:11484122chr2:66775075ENST00000398506611262_269294464.0Compositional biasNote=Poly-Asp
TgeneMEIS1chr2:11484121chr2:66775074ENST00000272369713272_3342961109.3333333333333DNA bindingHomeobox%3B TALE-type
TgeneMEIS1chr2:11484121chr2:66775074ENST00000398506611272_334294464.0DNA bindingHomeobox%3B TALE-type
TgeneMEIS1chr2:11484122chr2:66775075ENST00000272369713272_3342961109.3333333333333DNA bindingHomeobox%3B TALE-type
TgeneMEIS1chr2:11484122chr2:66775075ENST00000398506611272_334294464.0DNA bindingHomeobox%3B TALE-type


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Fusion Gene Sequence for ROCK2-MEIS1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>75331_75331_1_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000272369_length(transcript)=3536nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGACCTATGAGTGGAATGGGCATGAATATGGGCATGGAGGGGCAGTGGCACTACATGTAACCTTCATCTAGTTAACCAATCGCAA
AGCAAGGGGGAAGGCTGCAAAGTATGCCAGGGGAGTATGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCC
AACCCCAGATGCCCCCCCATCCTGCTCAGCTGCGTCATGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGA
TGATGCATGGAGGACCGCCCCACCCTGGAATGCCAATGTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGAC
AAGTCATGGACATTCATGCTCAGTAGCTTAAGGGAATATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGAC
TGTGGAGTTCCATTCTTGGCATCTACTCTGGACCAAGGAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGA
AGTCAATTTGGGGGACATGCTAAATAACTATATAAGACATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCAT
ATTACGTTGTTTCTTATAGATTTTTTAAAAAAAATGTGAAATTTTTCCACACTATGTGTGTTGTTTCCATAGCTCTTCACTTCCTCCAGA
AGCCTCCTTACATTAAAAAGCCTTACAGTTATCCTGCAAGGGACAGGAAGGTCTGATTTGCAGGATTTTTAGAGCATTAAAATAACTATC
AGGCAGAAGAATCTTTCTTCTCGCCTAGGATTTCAGCCATGCGCGCGCTCTCTCTCTTTCTCTCTCTTTTCCTCTCTCTCCCTCTTTCTA
GCCTGGGGCTTGAATTTGCATGTCTAATTCATTTACTCACCATATTTGAATTGGCCTGAACAGATGTAAATCGGGAAGGATGGGAAAAAC
TGCAGTCATCAACAATGATTAATCAGCTGTTGCAGGCAGTGTCTTAAGGAGACTGGTAGGAGGAGGCATGGAAACCAAAAGGCCGTGTGT
TTAGAAGCCTAATTGTCACATCAAGCATCATTGTCCCCATGCAACAACCACCACCTTATACATCACTTCCTGTTTTAAGCAGCTCTAAAA
CATAGACTGAAGATTTATTTTTAATATGTTGACTTTATTTCTGAGCAAAGCATCGGTCATGTGTGTATTTTTTCATAGTCCCACCTTGGA
GCATTTATGTAGACATTGTAAATAAATTTTGTGCAAAAAGGACTGGAAAAATGAACTGTATTATTGCAATTTTTTTTTGTAAAAGTAGCA
GTTTGGTATGAGTTGGCATGCATACAAGATTTACTAAGTGGGATAAGCTAATTATACTTTTTGTTGTGGATAAACAAATGCTTGTTGATA
GCCTTTTTCTATCAAGAAACCAAGGAGCTAATTATTAATAACAATCATTGCACACTGAGTCTTAGCGTTTCTGATGGAAACAGTTTGGAT
TGTATAATAACGCCAAGCCCAGTTGTAGTCGTTTGAGTGCAGTAATGAAATCTGAATCTAAAATAAAAACAAGATTATTTTTGTCATGCT
GACTCCACTGCTTGAAAAATTTGTTTACTGCCCCCCAGATTTTTAAAGATTAATACAGTAAATATAAAAATTAATTTTGGCTCCCTAAGC
CATATATGTATTTGACAATTTTAACCGCAAAGTAAGTTGTTTAATAATAACCACTGATTTCTTTAAGCTGACTTAATGAACTCCTAATAT
CAGCAAATTTGAGGCCTAAAGGCACTAAACTAACTCTAGACTCAGAATTACATCCAACAGAATTACTCATCTAATATCAGTGAAATTATT
CTTGCACATAAAGGCAAACCTAAGTACAAAGTTAAGTCTTTTACTAAAGGATGTTACCTAGGATGAGCAGTATATGTTTATTAGGAAATT
AACTACATGAATTGAAGAGACCAGACTTCAAAATCTAATTTTTATAAATATGCTCTATGTTCTCATTGGATAAAACTGGTTATTAACCAA
TTTTCCAGAACAGCTGTACAAGATTTCTGCATGGCAGCCGGCTAAATGGTAGAAAATAATATGTTTAAGCTGGAATAGCTTATAATTTTA
TTTAAATAAAATTGCTGCTATAAAAAGTGCTTCCCAAAGCTAAGGAAAATATACAAATATTTTAATTAAGGCAAATTCGTTTTAAAAAAT
AAGCCTTTCAGTAGTGATTGCTTTGTAAACAAAGGATGGGTCGGAGGAGAGAGAGCCTTAAACTCAAGTCTGACATTCAGGCCCAAGTCA
CCCTATAAACCGGCCCTTAGCAATTCTATTTTCTATTCGAAAAGAGAAACCAGCTGTGGGTTGGCTTTACTAGGTGATGTGTGATTGACT
GACTCACCTGCTGGAGTAGCAATGCATTCTCACCTTTTGCTGATGGGGCCTTGTTTCTAAACACGTGGATGCGCAGAGAGCAAGGCTCAG
CCTACTGCAGCCATCTCTGGCAGCGCTTCTACCCCTCCCCAGCCCATAGATGGGATTGTTTAAATCTCCCTTGTTGACCTAGTGGCAATT
CTTCCTCTACCTAAATAGTCGATGTGAGTGAAATCATTCTCTTTTGATAGGTGGTTGCTAGCAGTTAACAACCATTTATTTACTTTAACA

>75331_75331_1_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000272369_length(amino acids)=157AA_BP=1
MPLHAHIHAHSTHRSWCSNSHMLLTVHYETSHGLSIRIIRCSLTYCSVGLVYHGLHYSSPGINKPIVHLKDGESRVLCQLLFLFFRRVRV

--------------------------------------------------------------
>75331_75331_2_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000398506_length(transcript)=2029nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGGCTGCAAAGTATGCCAGGGGAGTATGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCCAACCCC
AGATGCCCCCCCATCCTGCTCAGCTGCGTCATGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGATGATGC
ATGGAGGACCGCCCCACCCTGGAATGCCAATGTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGACAAGTCA
TGGACATTCATGCTCAGTAGCTTAAGGGAATATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGACTGTGGA
GTTCCATTCTTGGCATCTACTCTGGACCAAGGAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGAAGTCAA
TTTGGGGGACATGCTAAATAACTATATAAGACATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCATATTACG
TTGTTTCTTATAGATTTTTTAAAAAAAATGTGAAATTTTTCCACACTATGTGTGTTGTTTCCATAGCTCTTCACTTCCTCCAGAAGCCTC
CTTACATTAAAAAGCCTTACAGTTATCCTGCAAGGGACAGGAAGGTCTGATTTGCAGGATTTTTAGAGCATTAAAATAACTATCAGGCAG
AAGAATCTTTCTTCTCGCCTAGGATTTCAGCCATGCGCGCGCTCTCTCTCTTTCTCTCTCTTTTCCTCTCTCTCCCTCTTTCTAGCCTGG
GGCTTGAATTTGCATGTCTAATTCATTTACTCACCATATTTGAATTGGCCTGAACAGATGTAAATCGGGAAGGATGGGAAAAACTGCAGT
CATCAACAATGATTAATCAGCTGTTGCAGGCAGTGTCTTAAGGAGACTGGTAGGAGGAGGCATGGAAACCAAAAGGCCGTGTGTTTAGAA
GCCTAATTGTCACATCAAGCATCATTGTCCCCATGCAACAACCACCACCTTATACATCACTTCCTGTTTTAAGCAGCTCTAAAACATAGA
CTGAAGATTTATTTTTAATATGTTGACTTTATTTCTGAGCAAAGCATCGGTCATGTGTGTATTTTTTCATAGTCCCACCTTGGAGCATTT

>75331_75331_2_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000398506_length(amino acids)=216AA_BP=41
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN
RAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSYTQPQMPPHPAQLRHGPPMHTYIPGHPHHPTVMM

--------------------------------------------------------------
>75331_75331_3_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000407092_length(transcript)=2329nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGGCTGCAAAGTATGCCAGGGGAGTATGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCCAACCCC
AGATGCCCCCCCATCCTGCTCAGCTGCGTCATGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGATGATGC
ATGGAGGACCGCCCCACCCTGGAATGCCAATGTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGACAAGTCA
TGGACATTCATGCTCAGTAGCTTAAGGGAATATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGACTGTGGA
GTTCCATTCTTGGCATCTACTCTGGACCAAGGAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGAAGTCAA
TTTGGGGGACATGCTAAATAACTATATAAGACATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCATATTACG
TTGTTTCTTATAGATTTTTTAAAAAAAATGTGAAATTTTTCCACACTATGTGTGTTGTTTCCATAGCTCTTCACTTCCTCCAGAAGCCTC
CTTACATTAAAAAGCCTTACAGTTATCCTGCAAGGGACAGGAAGGTCTGATTTGCAGGATTTTTAGAGCATTAAAATAACTATCAGGCAG
AAGAATCTTTCTTCTCGCCTAGGATTTCAGCCATGCGCGCGCTCTCTCTCTTTCTCTCTCTTTTCCTCTCTCTCCCTCTTTCTAGCCTGG
GGCTTGAATTTGCATGTCTAATTCATTTACTCACCATATTTGAATTGGCCTGAACAGATGTAAATCGGGAAGGATGGGAAAAACTGCAGT
CATCAACAATGATTAATCAGCTGTTGCAGGCAGTGTCTTAAGGAGACTGGTAGGAGGAGGCATGGAAACCAAAAGGCCGTGTGTTTAGAA
GCCTAATTGTCACATCAAGCATCATTGTCCCCATGCAACAACCACCACCTTATACATCACTTCCTGTTTTAAGCAGCTCTAAAACATAGA
CTGAAGATTTATTTTTAATATGTTGACTTTATTTCTGAGCAAAGCATCGGTCATGTGTGTATTTTTTCATAGTCCCACCTTGGAGCATTT
ATGTAGACATTGTAAATAAATTTTGTGCAAAAAGGACTGGAAAAATGAACTGTATTATTGCAATTTTTTTTTGTAAAAGTAGCAGTTTGG
TATGAGTTGGCATGCATACAAGATTTACTAAGTGGGATAAGCTAATTATACTTTTTGTTGTGGATAAACAAATGCTTGTTGATAGCCTTT
TTCTATCAAGAAACCAAGGAGCTAATTATTAATAACAATCATTGCACACTGAGTCTTAGCGTTTCTGATGGAAACAGTTTGGATTGTATA

>75331_75331_3_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000407092_length(amino acids)=216AA_BP=41
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN
RAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSYTQPQMPPHPAQLRHGPPMHTYIPGHPHHPTVMM

--------------------------------------------------------------
>75331_75331_4_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000444274_length(transcript)=1429nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGGCTGCAAAGTATGCCAGGGGAGTATGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCCAACCCC
AGATGCCCCCCCATCCTGCTCAGCTGCGTCATGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGATGATGC
ATGGAGGACCGCCCCACCCTGGAATGCCAATGTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGACAAGTCA
TGGACATTCATGCTCAGTAGCTTAAGGGAATATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGACTGTGGA
GTTCCATTCTTGGCATCTACTCTGGACCAAGGAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGAAGTCAA
TTTGGGGGACATGCTAAATAACTATATAAGACATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCATATTACG

>75331_75331_4_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000444274_length(amino acids)=216AA_BP=41
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN
RAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSYTQPQMPPHPAQLRHGPPMHTYIPGHPHHPTVMM

--------------------------------------------------------------
>75331_75331_5_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000488550_length(transcript)=4514nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGTAAGACTTTGTTTTTGTGGTAGTTCCTCATTTTTGACTCCAAGAGTGTCATCCCCTCATCAACACAGGTAAATCCGCCTCATC
CTTTTCTGTTATCTCAAGCTGGCTGCCTTGCCTTGTCTGCTATCTGTGCATCTAAGATATTGCAGAGGGGAAGCCAGGATCTTTATGCAC
TGAAGATCTCACTATTTCTCAACCCTCTAGATCCTGTTTTTTTTTTAAGGGTCTTTTGGCACTATCTGTTGACTTTGCTCATTTTCTGGC
CTCTTCTTGGATTTTTATCTCCCTTCTAGGACCTATGAGTGGAATGGGCATGAATATGGGCATGGAGGGGCAGTGGCACTACATGTAACC
TTCATCTAGTTAACCAATCGCAAAGCAAGGGGGAAGTAAGTACAAATGGGGTCTTTGTTTTCACTTTGTCCTAGGAATATTTTTCCTCTT
GCATTTTCTTATGTTCTCCTTGCCCATAGCTTCATGCTTGTTCATTCCTTTCCATTAAACTCCTGGTTTCTTGCTTCCATCATTTTCTTT
TTGGTTGTGATCAAGCTTTTAAGCTTATAAATACTGTGTATGATGTACATTTATCCTGTGTGTTGCTATTGTACAGTACTGACCACATGA
CAAAACAAGAAGCAGTCAGGAGGTGGGGGAGTGGGTTGTCATAGCAACAGACTGATTTGCAAAATGTAAGCAGTCTGCAGCAGTGCAAGG
AGAGGGAAGAGCATGTCCCCAAAGTGTCATAAATCTGTCTAACCGCAGTTGATGCATGAGTTACATTTCTACACTAACCTGCAAGACACC
GAAAAGCTAAACAGAGACTTCTTTTAGGTAAAATAAACACAAGCTTTACTTAGGGTAAGTAAAGGCATATTTTGAGCTCCAGTCAACTAA
ACTTTGATTTTTTTTCTTAGTTTATTCCTTTGTCTGTCCATCATAATGGGATTACGTGTGGCAATGGGAAAAGGGAGAATACAAAATAGA
GGTGTGCACAGCAGGCTGCGGGGCTTAGCCCAGGCTAATTGACTATATCCAAATTAAGTATGCCATCACTTGCAGTGTGACAAATGGATT
TGACTTATTCAGTATACAAAAATAGAGATCATTAATGCAATCATCAGTGGCAGGCCTAGTGAAGTGGGCCTAGGAAAACTGTCCCAGATT
CTCACTCTTGCATTTTCTCTCCTATAAAGACACTCCAGCAATTCGAGTTCAAACAAGTAAAACTGTTTTGAACACCAAGGCTCTTGTTCA
CTTCCTAAATTACCCCTAATAGCACTGTTCTTGCTTTGTTTTTGAAATTAAAAGCAGTTATTTCAGAGTCTTGCTTGTGTCTCTGATTAT
ATTTATGCACTATTTAAAATCACTGCTGAGGCCAGGGGTAATTCGTACTGGTCATCTTCTCTGGGTGTGAGTCAAATATAAGTTTAACAA
TTAGCTCTGAAAACATTCCATTGAGCTGGGGAATGCAACAGTCTTATTACCTCATCATGGAATTCTCTAGCTTAGTTAATTTAAATATTG
TTTCTTAGTTTCTGGGTCAATTAAATTTAAATGATGTATTTTATGCTTCGTGACCAATTAAATTACTAGGTTATTACAAAAAAAATTATC
ATCTTTTTTGATTAAAGAGCTGTGGGTACAGTATATTTTATAAGCAATTTTCATTAGTTCAAAAATGTTCCTTTAGGCTAGATTAAGCAG
CCATTCATTGTTAGAGCCTGGAGACCTTATTCGAAGGTGTTCATCGTATTCACAGTGCACTATTACTTAGAACTAAAGCCAATTGAACCT
ACTTAGCAATAGCGTTATGCCTTTCACCCTTGATGATTATGGAGCTTATAGCTCTCAGAAACAATACACCTGTCAGTTTCCATCAACTAT
AGCAATCCATGCAGAAGACAAGAGGCCCCCTCAAAGCAGGAGGGGTATTGTTTTAGGTCCAATTTTTCTTATTGTTCTCAAAATCATTAT
AAGGTGGACAGTGTTTTGTGAAGATTTTCTTTTCCCCAGCTCTAAGAAACCATGTGGAAAGAATTCATTGATAACTGTTTTGATTTTTTT
CTTTTTTTAAGTACAGGTTTTGCTAAGTAATCACCCTTAGTGAGCCTGTGTAGTTCAGCTGCCTGTGAGATGTTTGGTGACCAGCTCAGT
GTATTCTTGTATTCTTGATAGAGAATATTTCAGGAGACAAAAGTGCTTCTTCAGACCAGACCTCAAATAACAATTTTATTCTTTTTAATA
AATAAGACCTCAGTAGGCGGACCTGATAACAGTGACAATGAAAGGAAAATAGTGGCAAAATGTGAGTTTCCAGCATGATGTTTCTCATTT
TATTTTCTTCTGTATGAATCAAAAGAATGCTTTACAAAACCATGTTCCCTTAATCACAGGGTTCTCTGGCTTTTATAGGATTGTCATAGC
CAGGACCACACTATTGCTTTTTCATAACATTTTCTTTTTGTTTCTTTCTTTTGAATTTCTTACAGGGCTGCAAAGTATGCCAGGGGAGTA
TGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCCAACCCCAGATGCCCCCCCATCCTGCTCAGCTGCGTCA
TGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGATGATGCATGGAGGACCGCCCCACCCTGGAATGCCAAT
GTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGACAAGTCATGGACATTCATGCTCAGTAGCTTAAGGGAAT
ATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGACTGTGGAGTTCCATTCTTGGCATCTACTCTGGACCAAG
GAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGAAGTCAATTTGGGGGACATGCTAAATAACTATATAAGA
CATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCATATTACGTTGTTTCTTATAGATTTTTTAAAAAAAATGT
GAAATTTTTCCACACTATGTGTGTTGTTTCCATAGCTCTTCACTTCCTCCAGAAGCCTCCTTACATTAAAAAGCCTTACAGTTATCCTGC
AAGGGACAGGAAGGTCTGATTTGCAGGATTTTTAGAGCATTAAAATAACTATCAGGCAGAAGAATCTTTCTTCTCGCCTAGGATTTCAGC
CATGCGCGCGCTCTCTCTCTTTCTCTCTCTTTTCCTCTCTCTCCCTCTTTCTAGCCTGGGGCTTGAATTTGCATGTCTAATTCATTTACT
CACCATATTTGAATTGGCCTGAACAGATGTAAATCGGGAAGGATGGGAAAAACTGCAGTCATCAACAATGATTAATCAGCTGTTGCAGGC
AGTGTCTTAAGGAGACTGGTAGGAGGAGGCATGGAAACCAAAAGGCCGTGTGTTTAGAAGCCTAATTGTCACATCAAGCATCATTGTCCC
CATGCAACAACCACCACCTTATACATCACTTCCTGTTTTAAGCAGCTCTAAAACATAGACTGAAGATTTATTTTTAATATGTTGACTTTA
TTTCTGAGCAAAGCATCGGTCATGTGTGTATTTTTTCATAGTCCCACCTTGGAGCATTTATGTAGACATTGTAAATAAATTTTGTGCAAA

>75331_75331_5_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000488550_length(amino acids)=141AA_BP=
MNQKNALQNHVPLITGFSGFYRIVIARTTLLLFHNIFFLFLSFEFLTGLQSMPGEYVARGGPMGVSMGQPSYTQPQMPPHPAQLRHGPPM

--------------------------------------------------------------
>75331_75331_6_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000495021_length(transcript)=1503nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGACCTATGAGTGGAATGGGCATGAATATGGGCATGGAGGGGCAGTGGCACTACATGTAACCTTCATCTAGTTAACCAATCGCAA
AGCAAGGGGGAAGGCTGCAAAGTATGCCAGGGGAGTATGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCC
AACCCCAGATGCCCCCCCATCCTGCTCAGCTGCGTCATGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGA
TGATGCATGGAGGACCGCCCCACCCTGGAATGCCAATGTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGAC
AAGTCATGGACATTCATGCTCAGTAGCTTAAGGGAATATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGAC
TGTGGAGTTCCATTCTTGGCATCTACTCTGGACCAAGGAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGA
AGTCAATTTGGGGGACATGCTAAATAACTATATAAGACATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCAT

>75331_75331_6_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000495021_length(amino acids)=172AA_BP=
MPRPPARSRGRRAFSPSAGAGSCRHRWTRTQAPRAQVPQPRGLAPPPNHQLRPGLHPGPPPASSSGFGSPRRSPAWGLLPGARPAQPGPA

--------------------------------------------------------------
>75331_75331_7_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000560281_length(transcript)=1751nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGGCAAGTCCCCCATAGTGACTGTATTCAAGTCACGCAAGCGAAAACCATCCTCAAGCCATTCACCGGGAGGTCCGCTACCTGGTA
AATAAACTGGGAGTGAGTATAGGAACGCCTGGCAATTAAAATTAAACCAGTTTCGTTTCATAACAACACTAATCAATTTAACATCATTAT
AAAACGTTTGGAGAAGGTGGAAAAAAAAAGCCAACAGAGAAAAGTAACTCTTAAATAATATGCTCAGTTACAATATTCTTTGTACACATT
CAATATATTAATGTTATTTTTTTTCTGAGTTTGCCTTCCCAGCTCTTTCTGCTACTATGACCACTCCCTGGTGCATGGCTTGGTGTGGAA
TTGCTGTAAACTTTATTACCTGTCAAAAGGGCAAAGGGGTCAGGATTGCTTGTGGGACTCAGTAAAGTTCAAAGACATTCAATGAGGTAG
AGCTTTTGTGTGCTTTAATAACCCAAGGCAGCTTACTTCTGAAGCAGCTTTTCATGTACAGTTAAAACACGGGATTCAGGTAGTGGTATA
AATACATGGTTCTTATTTCTCAGACCTTCTCTTGTTAATATCCATCTTCTGGTGTTCGACTTTTTTTTTTTTTAATAACAGTCTTTTTGT
TTTGTTTTTAAATTATGAGCTTAAAATGGCGATACTTCTATGGGATCCTGGCTTGTGGATCTAAAAATCCAAGAAACATCTCTCTAGGAT
TTGTTTTTGCATTATAATATGCCAGTAAGATAACAAGAGTATTTGCTAGGGGTGATGTGAGTCTTTACTTTCTTTATGAAATACTCTCTC
ATCTCTTAGGGAGCACTATGGAAAACTATGTTAGCATCGCATTGAGGCAACACACATTTACTCCTGTAACTTTTTTTCTTCCAACACCCA
TTATGTGGTCACCAGACAAAACCCAAGCAGAAAGTTTCCACACCTTAACTGTTCCCTCTTTGAGCTAGATGTTTTAAAAACTCAGTCACA

>75331_75331_7_ROCK2-MEIS1_ROCK2_chr2_11484121_ENST00000315872_MEIS1_chr2_66775074_ENST00000560281_length(amino acids)=121AA_BP=41
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN

--------------------------------------------------------------
>75331_75331_8_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000272369_length(transcript)=3536nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGACCTATGAGTGGAATGGGCATGAATATGGGCATGGAGGGGCAGTGGCACTACATGTAACCTTCATCTAGTTAACCAATCGCAA
AGCAAGGGGGAAGGCTGCAAAGTATGCCAGGGGAGTATGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCC
AACCCCAGATGCCCCCCCATCCTGCTCAGCTGCGTCATGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGA
TGATGCATGGAGGACCGCCCCACCCTGGAATGCCAATGTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGAC
AAGTCATGGACATTCATGCTCAGTAGCTTAAGGGAATATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGAC
TGTGGAGTTCCATTCTTGGCATCTACTCTGGACCAAGGAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGA
AGTCAATTTGGGGGACATGCTAAATAACTATATAAGACATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCAT
ATTACGTTGTTTCTTATAGATTTTTTAAAAAAAATGTGAAATTTTTCCACACTATGTGTGTTGTTTCCATAGCTCTTCACTTCCTCCAGA
AGCCTCCTTACATTAAAAAGCCTTACAGTTATCCTGCAAGGGACAGGAAGGTCTGATTTGCAGGATTTTTAGAGCATTAAAATAACTATC
AGGCAGAAGAATCTTTCTTCTCGCCTAGGATTTCAGCCATGCGCGCGCTCTCTCTCTTTCTCTCTCTTTTCCTCTCTCTCCCTCTTTCTA
GCCTGGGGCTTGAATTTGCATGTCTAATTCATTTACTCACCATATTTGAATTGGCCTGAACAGATGTAAATCGGGAAGGATGGGAAAAAC
TGCAGTCATCAACAATGATTAATCAGCTGTTGCAGGCAGTGTCTTAAGGAGACTGGTAGGAGGAGGCATGGAAACCAAAAGGCCGTGTGT
TTAGAAGCCTAATTGTCACATCAAGCATCATTGTCCCCATGCAACAACCACCACCTTATACATCACTTCCTGTTTTAAGCAGCTCTAAAA
CATAGACTGAAGATTTATTTTTAATATGTTGACTTTATTTCTGAGCAAAGCATCGGTCATGTGTGTATTTTTTCATAGTCCCACCTTGGA
GCATTTATGTAGACATTGTAAATAAATTTTGTGCAAAAAGGACTGGAAAAATGAACTGTATTATTGCAATTTTTTTTTGTAAAAGTAGCA
GTTTGGTATGAGTTGGCATGCATACAAGATTTACTAAGTGGGATAAGCTAATTATACTTTTTGTTGTGGATAAACAAATGCTTGTTGATA
GCCTTTTTCTATCAAGAAACCAAGGAGCTAATTATTAATAACAATCATTGCACACTGAGTCTTAGCGTTTCTGATGGAAACAGTTTGGAT
TGTATAATAACGCCAAGCCCAGTTGTAGTCGTTTGAGTGCAGTAATGAAATCTGAATCTAAAATAAAAACAAGATTATTTTTGTCATGCT
GACTCCACTGCTTGAAAAATTTGTTTACTGCCCCCCAGATTTTTAAAGATTAATACAGTAAATATAAAAATTAATTTTGGCTCCCTAAGC
CATATATGTATTTGACAATTTTAACCGCAAAGTAAGTTGTTTAATAATAACCACTGATTTCTTTAAGCTGACTTAATGAACTCCTAATAT
CAGCAAATTTGAGGCCTAAAGGCACTAAACTAACTCTAGACTCAGAATTACATCCAACAGAATTACTCATCTAATATCAGTGAAATTATT
CTTGCACATAAAGGCAAACCTAAGTACAAAGTTAAGTCTTTTACTAAAGGATGTTACCTAGGATGAGCAGTATATGTTTATTAGGAAATT
AACTACATGAATTGAAGAGACCAGACTTCAAAATCTAATTTTTATAAATATGCTCTATGTTCTCATTGGATAAAACTGGTTATTAACCAA
TTTTCCAGAACAGCTGTACAAGATTTCTGCATGGCAGCCGGCTAAATGGTAGAAAATAATATGTTTAAGCTGGAATAGCTTATAATTTTA
TTTAAATAAAATTGCTGCTATAAAAAGTGCTTCCCAAAGCTAAGGAAAATATACAAATATTTTAATTAAGGCAAATTCGTTTTAAAAAAT
AAGCCTTTCAGTAGTGATTGCTTTGTAAACAAAGGATGGGTCGGAGGAGAGAGAGCCTTAAACTCAAGTCTGACATTCAGGCCCAAGTCA
CCCTATAAACCGGCCCTTAGCAATTCTATTTTCTATTCGAAAAGAGAAACCAGCTGTGGGTTGGCTTTACTAGGTGATGTGTGATTGACT
GACTCACCTGCTGGAGTAGCAATGCATTCTCACCTTTTGCTGATGGGGCCTTGTTTCTAAACACGTGGATGCGCAGAGAGCAAGGCTCAG
CCTACTGCAGCCATCTCTGGCAGCGCTTCTACCCCTCCCCAGCCCATAGATGGGATTGTTTAAATCTCCCTTGTTGACCTAGTGGCAATT
CTTCCTCTACCTAAATAGTCGATGTGAGTGAAATCATTCTCTTTTGATAGGTGGTTGCTAGCAGTTAACAACCATTTATTTACTTTAACA

>75331_75331_8_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000272369_length(amino acids)=157AA_BP=1
MPLHAHIHAHSTHRSWCSNSHMLLTVHYETSHGLSIRIIRCSLTYCSVGLVYHGLHYSSPGINKPIVHLKDGESRVLCQLLFLFFRRVRV

--------------------------------------------------------------
>75331_75331_9_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000398506_length(transcript)=2029nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGGCTGCAAAGTATGCCAGGGGAGTATGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCCAACCCC
AGATGCCCCCCCATCCTGCTCAGCTGCGTCATGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGATGATGC
ATGGAGGACCGCCCCACCCTGGAATGCCAATGTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGACAAGTCA
TGGACATTCATGCTCAGTAGCTTAAGGGAATATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGACTGTGGA
GTTCCATTCTTGGCATCTACTCTGGACCAAGGAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGAAGTCAA
TTTGGGGGACATGCTAAATAACTATATAAGACATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCATATTACG
TTGTTTCTTATAGATTTTTTAAAAAAAATGTGAAATTTTTCCACACTATGTGTGTTGTTTCCATAGCTCTTCACTTCCTCCAGAAGCCTC
CTTACATTAAAAAGCCTTACAGTTATCCTGCAAGGGACAGGAAGGTCTGATTTGCAGGATTTTTAGAGCATTAAAATAACTATCAGGCAG
AAGAATCTTTCTTCTCGCCTAGGATTTCAGCCATGCGCGCGCTCTCTCTCTTTCTCTCTCTTTTCCTCTCTCTCCCTCTTTCTAGCCTGG
GGCTTGAATTTGCATGTCTAATTCATTTACTCACCATATTTGAATTGGCCTGAACAGATGTAAATCGGGAAGGATGGGAAAAACTGCAGT
CATCAACAATGATTAATCAGCTGTTGCAGGCAGTGTCTTAAGGAGACTGGTAGGAGGAGGCATGGAAACCAAAAGGCCGTGTGTTTAGAA
GCCTAATTGTCACATCAAGCATCATTGTCCCCATGCAACAACCACCACCTTATACATCACTTCCTGTTTTAAGCAGCTCTAAAACATAGA
CTGAAGATTTATTTTTAATATGTTGACTTTATTTCTGAGCAAAGCATCGGTCATGTGTGTATTTTTTCATAGTCCCACCTTGGAGCATTT

>75331_75331_9_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000398506_length(amino acids)=216AA_BP=41
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN
RAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSYTQPQMPPHPAQLRHGPPMHTYIPGHPHHPTVMM

--------------------------------------------------------------
>75331_75331_10_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000407092_length(transcript)=2329nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGGCTGCAAAGTATGCCAGGGGAGTATGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCCAACCCC
AGATGCCCCCCCATCCTGCTCAGCTGCGTCATGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGATGATGC
ATGGAGGACCGCCCCACCCTGGAATGCCAATGTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGACAAGTCA
TGGACATTCATGCTCAGTAGCTTAAGGGAATATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGACTGTGGA
GTTCCATTCTTGGCATCTACTCTGGACCAAGGAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGAAGTCAA
TTTGGGGGACATGCTAAATAACTATATAAGACATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCATATTACG
TTGTTTCTTATAGATTTTTTAAAAAAAATGTGAAATTTTTCCACACTATGTGTGTTGTTTCCATAGCTCTTCACTTCCTCCAGAAGCCTC
CTTACATTAAAAAGCCTTACAGTTATCCTGCAAGGGACAGGAAGGTCTGATTTGCAGGATTTTTAGAGCATTAAAATAACTATCAGGCAG
AAGAATCTTTCTTCTCGCCTAGGATTTCAGCCATGCGCGCGCTCTCTCTCTTTCTCTCTCTTTTCCTCTCTCTCCCTCTTTCTAGCCTGG
GGCTTGAATTTGCATGTCTAATTCATTTACTCACCATATTTGAATTGGCCTGAACAGATGTAAATCGGGAAGGATGGGAAAAACTGCAGT
CATCAACAATGATTAATCAGCTGTTGCAGGCAGTGTCTTAAGGAGACTGGTAGGAGGAGGCATGGAAACCAAAAGGCCGTGTGTTTAGAA
GCCTAATTGTCACATCAAGCATCATTGTCCCCATGCAACAACCACCACCTTATACATCACTTCCTGTTTTAAGCAGCTCTAAAACATAGA
CTGAAGATTTATTTTTAATATGTTGACTTTATTTCTGAGCAAAGCATCGGTCATGTGTGTATTTTTTCATAGTCCCACCTTGGAGCATTT
ATGTAGACATTGTAAATAAATTTTGTGCAAAAAGGACTGGAAAAATGAACTGTATTATTGCAATTTTTTTTTGTAAAAGTAGCAGTTTGG
TATGAGTTGGCATGCATACAAGATTTACTAAGTGGGATAAGCTAATTATACTTTTTGTTGTGGATAAACAAATGCTTGTTGATAGCCTTT
TTCTATCAAGAAACCAAGGAGCTAATTATTAATAACAATCATTGCACACTGAGTCTTAGCGTTTCTGATGGAAACAGTTTGGATTGTATA

>75331_75331_10_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000407092_length(amino acids)=216AA_BP=41
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN
RAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSYTQPQMPPHPAQLRHGPPMHTYIPGHPHHPTVMM

--------------------------------------------------------------
>75331_75331_11_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000444274_length(transcript)=1429nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGGCTGCAAAGTATGCCAGGGGAGTATGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCCAACCCC
AGATGCCCCCCCATCCTGCTCAGCTGCGTCATGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGATGATGC
ATGGAGGACCGCCCCACCCTGGAATGCCAATGTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGACAAGTCA
TGGACATTCATGCTCAGTAGCTTAAGGGAATATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGACTGTGGA
GTTCCATTCTTGGCATCTACTCTGGACCAAGGAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGAAGTCAA
TTTGGGGGACATGCTAAATAACTATATAAGACATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCATATTACG

>75331_75331_11_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000444274_length(amino acids)=216AA_BP=41
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN
RAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSYTQPQMPPHPAQLRHGPPMHTYIPGHPHHPTVMM

--------------------------------------------------------------
>75331_75331_12_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000488550_length(transcript)=4514nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGTAAGACTTTGTTTTTGTGGTAGTTCCTCATTTTTGACTCCAAGAGTGTCATCCCCTCATCAACACAGGTAAATCCGCCTCATC
CTTTTCTGTTATCTCAAGCTGGCTGCCTTGCCTTGTCTGCTATCTGTGCATCTAAGATATTGCAGAGGGGAAGCCAGGATCTTTATGCAC
TGAAGATCTCACTATTTCTCAACCCTCTAGATCCTGTTTTTTTTTTAAGGGTCTTTTGGCACTATCTGTTGACTTTGCTCATTTTCTGGC
CTCTTCTTGGATTTTTATCTCCCTTCTAGGACCTATGAGTGGAATGGGCATGAATATGGGCATGGAGGGGCAGTGGCACTACATGTAACC
TTCATCTAGTTAACCAATCGCAAAGCAAGGGGGAAGTAAGTACAAATGGGGTCTTTGTTTTCACTTTGTCCTAGGAATATTTTTCCTCTT
GCATTTTCTTATGTTCTCCTTGCCCATAGCTTCATGCTTGTTCATTCCTTTCCATTAAACTCCTGGTTTCTTGCTTCCATCATTTTCTTT
TTGGTTGTGATCAAGCTTTTAAGCTTATAAATACTGTGTATGATGTACATTTATCCTGTGTGTTGCTATTGTACAGTACTGACCACATGA
CAAAACAAGAAGCAGTCAGGAGGTGGGGGAGTGGGTTGTCATAGCAACAGACTGATTTGCAAAATGTAAGCAGTCTGCAGCAGTGCAAGG
AGAGGGAAGAGCATGTCCCCAAAGTGTCATAAATCTGTCTAACCGCAGTTGATGCATGAGTTACATTTCTACACTAACCTGCAAGACACC
GAAAAGCTAAACAGAGACTTCTTTTAGGTAAAATAAACACAAGCTTTACTTAGGGTAAGTAAAGGCATATTTTGAGCTCCAGTCAACTAA
ACTTTGATTTTTTTTCTTAGTTTATTCCTTTGTCTGTCCATCATAATGGGATTACGTGTGGCAATGGGAAAAGGGAGAATACAAAATAGA
GGTGTGCACAGCAGGCTGCGGGGCTTAGCCCAGGCTAATTGACTATATCCAAATTAAGTATGCCATCACTTGCAGTGTGACAAATGGATT
TGACTTATTCAGTATACAAAAATAGAGATCATTAATGCAATCATCAGTGGCAGGCCTAGTGAAGTGGGCCTAGGAAAACTGTCCCAGATT
CTCACTCTTGCATTTTCTCTCCTATAAAGACACTCCAGCAATTCGAGTTCAAACAAGTAAAACTGTTTTGAACACCAAGGCTCTTGTTCA
CTTCCTAAATTACCCCTAATAGCACTGTTCTTGCTTTGTTTTTGAAATTAAAAGCAGTTATTTCAGAGTCTTGCTTGTGTCTCTGATTAT
ATTTATGCACTATTTAAAATCACTGCTGAGGCCAGGGGTAATTCGTACTGGTCATCTTCTCTGGGTGTGAGTCAAATATAAGTTTAACAA
TTAGCTCTGAAAACATTCCATTGAGCTGGGGAATGCAACAGTCTTATTACCTCATCATGGAATTCTCTAGCTTAGTTAATTTAAATATTG
TTTCTTAGTTTCTGGGTCAATTAAATTTAAATGATGTATTTTATGCTTCGTGACCAATTAAATTACTAGGTTATTACAAAAAAAATTATC
ATCTTTTTTGATTAAAGAGCTGTGGGTACAGTATATTTTATAAGCAATTTTCATTAGTTCAAAAATGTTCCTTTAGGCTAGATTAAGCAG
CCATTCATTGTTAGAGCCTGGAGACCTTATTCGAAGGTGTTCATCGTATTCACAGTGCACTATTACTTAGAACTAAAGCCAATTGAACCT
ACTTAGCAATAGCGTTATGCCTTTCACCCTTGATGATTATGGAGCTTATAGCTCTCAGAAACAATACACCTGTCAGTTTCCATCAACTAT
AGCAATCCATGCAGAAGACAAGAGGCCCCCTCAAAGCAGGAGGGGTATTGTTTTAGGTCCAATTTTTCTTATTGTTCTCAAAATCATTAT
AAGGTGGACAGTGTTTTGTGAAGATTTTCTTTTCCCCAGCTCTAAGAAACCATGTGGAAAGAATTCATTGATAACTGTTTTGATTTTTTT
CTTTTTTTAAGTACAGGTTTTGCTAAGTAATCACCCTTAGTGAGCCTGTGTAGTTCAGCTGCCTGTGAGATGTTTGGTGACCAGCTCAGT
GTATTCTTGTATTCTTGATAGAGAATATTTCAGGAGACAAAAGTGCTTCTTCAGACCAGACCTCAAATAACAATTTTATTCTTTTTAATA
AATAAGACCTCAGTAGGCGGACCTGATAACAGTGACAATGAAAGGAAAATAGTGGCAAAATGTGAGTTTCCAGCATGATGTTTCTCATTT
TATTTTCTTCTGTATGAATCAAAAGAATGCTTTACAAAACCATGTTCCCTTAATCACAGGGTTCTCTGGCTTTTATAGGATTGTCATAGC
CAGGACCACACTATTGCTTTTTCATAACATTTTCTTTTTGTTTCTTTCTTTTGAATTTCTTACAGGGCTGCAAAGTATGCCAGGGGAGTA
TGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCCAACCCCAGATGCCCCCCCATCCTGCTCAGCTGCGTCA
TGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGATGATGCATGGAGGACCGCCCCACCCTGGAATGCCAAT
GTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGACAAGTCATGGACATTCATGCTCAGTAGCTTAAGGGAAT
ATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGACTGTGGAGTTCCATTCTTGGCATCTACTCTGGACCAAG
GAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGAAGTCAATTTGGGGGACATGCTAAATAACTATATAAGA
CATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCATATTACGTTGTTTCTTATAGATTTTTTAAAAAAAATGT
GAAATTTTTCCACACTATGTGTGTTGTTTCCATAGCTCTTCACTTCCTCCAGAAGCCTCCTTACATTAAAAAGCCTTACAGTTATCCTGC
AAGGGACAGGAAGGTCTGATTTGCAGGATTTTTAGAGCATTAAAATAACTATCAGGCAGAAGAATCTTTCTTCTCGCCTAGGATTTCAGC
CATGCGCGCGCTCTCTCTCTTTCTCTCTCTTTTCCTCTCTCTCCCTCTTTCTAGCCTGGGGCTTGAATTTGCATGTCTAATTCATTTACT
CACCATATTTGAATTGGCCTGAACAGATGTAAATCGGGAAGGATGGGAAAAACTGCAGTCATCAACAATGATTAATCAGCTGTTGCAGGC
AGTGTCTTAAGGAGACTGGTAGGAGGAGGCATGGAAACCAAAAGGCCGTGTGTTTAGAAGCCTAATTGTCACATCAAGCATCATTGTCCC
CATGCAACAACCACCACCTTATACATCACTTCCTGTTTTAAGCAGCTCTAAAACATAGACTGAAGATTTATTTTTAATATGTTGACTTTA
TTTCTGAGCAAAGCATCGGTCATGTGTGTATTTTTTCATAGTCCCACCTTGGAGCATTTATGTAGACATTGTAAATAAATTTTGTGCAAA

>75331_75331_12_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000488550_length(amino acids)=141AA_BP=
MNQKNALQNHVPLITGFSGFYRIVIARTTLLLFHNIFFLFLSFEFLTGLQSMPGEYVARGGPMGVSMGQPSYTQPQMPPHPAQLRHGPPM

--------------------------------------------------------------
>75331_75331_13_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000495021_length(transcript)=1503nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGTAAGTCAAGGAACACCTTATAATCCTGATGGACAGCCCATGGGAGGTTTCGTAATGGACGGTCAGCAACATATGGGAATTAGAG
CACCAGGACCTATGAGTGGAATGGGCATGAATATGGGCATGGAGGGGCAGTGGCACTACATGTAACCTTCATCTAGTTAACCAATCGCAA
AGCAAGGGGGAAGGCTGCAAAGTATGCCAGGGGAGTATGTAGCCCGGGGTGGTCCAATGGGTGTGAGTATGGGACAGCCAAGTTATACCC
AACCCCAGATGCCCCCCCATCCTGCTCAGCTGCGTCATGGGCCCCCCATGCATACGTACATTCCTGGACACCCTCACCACCCAACAGTGA
TGATGCATGGAGGACCGCCCCACCCTGGAATGCCAATGTCAGCATCAAGCCCCACAGTTCTTAATACAGGAGACCCAACAATGAGTGGAC
AAGTCATGGACATTCATGCTCAGTAGCTTAAGGGAATATGCATTGTCTGCAATGGTGACTGATTTCAAATCATGTTTTTTCTGCAATGAC
TGTGGAGTTCCATTCTTGGCATCTACTCTGGACCAAGGAGCATCCCTAATTCTTCATAGGGACCTTTAAAAAGCAGGAAATACCAACTGA
AGTCAATTTGGGGGACATGCTAAATAACTATATAAGACATTAAGAGAACAAAGAGTGAAATATTGTAAATGCTATTATACTGTTATCCAT

>75331_75331_13_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000495021_length(amino acids)=172AA_BP=
MPRPPARSRGRRAFSPSAGAGSCRHRWTRTQAPRAQVPQPRGLAPPPNHQLRPGLHPGPPPASSSGFGSPRRSPAWGLLPGARPAQPGPA

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>75331_75331_14_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000560281_length(transcript)=1751nt_BP=590nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGCACCCTTACCCTTCTGAAGAACAGAAAAAGCAGTTGGCAC
AAGACACGGGACTCACCATCCTTCAAGTGAACAATTGGTTTATTAATGCCCGGAGAAGAATAGTGCAGCCCATGATAGACCAGTCCAACC
GAGCAGGCAAGTCCCCCATAGTGACTGTATTCAAGTCACGCAAGCGAAAACCATCCTCAAGCCATTCACCGGGAGGTCCGCTACCTGGTA
AATAAACTGGGAGTGAGTATAGGAACGCCTGGCAATTAAAATTAAACCAGTTTCGTTTCATAACAACACTAATCAATTTAACATCATTAT
AAAACGTTTGGAGAAGGTGGAAAAAAAAAGCCAACAGAGAAAAGTAACTCTTAAATAATATGCTCAGTTACAATATTCTTTGTACACATT
CAATATATTAATGTTATTTTTTTTCTGAGTTTGCCTTCCCAGCTCTTTCTGCTACTATGACCACTCCCTGGTGCATGGCTTGGTGTGGAA
TTGCTGTAAACTTTATTACCTGTCAAAAGGGCAAAGGGGTCAGGATTGCTTGTGGGACTCAGTAAAGTTCAAAGACATTCAATGAGGTAG
AGCTTTTGTGTGCTTTAATAACCCAAGGCAGCTTACTTCTGAAGCAGCTTTTCATGTACAGTTAAAACACGGGATTCAGGTAGTGGTATA
AATACATGGTTCTTATTTCTCAGACCTTCTCTTGTTAATATCCATCTTCTGGTGTTCGACTTTTTTTTTTTTTAATAACAGTCTTTTTGT
TTTGTTTTTAAATTATGAGCTTAAAATGGCGATACTTCTATGGGATCCTGGCTTGTGGATCTAAAAATCCAAGAAACATCTCTCTAGGAT
TTGTTTTTGCATTATAATATGCCAGTAAGATAACAAGAGTATTTGCTAGGGGTGATGTGAGTCTTTACTTTCTTTATGAAATACTCTCTC
ATCTCTTAGGGAGCACTATGGAAAACTATGTTAGCATCGCATTGAGGCAACACACATTTACTCCTGTAACTTTTTTTCTTCCAACACCCA
TTATGTGGTCACCAGACAAAACCCAAGCAGAAAGTTTCCACACCTTAACTGTTCCCTCTTTGAGCTAGATGTTTTAAAAACTCAGTCACA

>75331_75331_14_ROCK2-MEIS1_ROCK2_chr2_11484122_ENST00000315872_MEIS1_chr2_66775075_ENST00000560281_length(amino acids)=121AA_BP=41
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN

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Fusion Gene PPI Analysis for ROCK2-MEIS1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneMEIS1chr2:11484121chr2:66775074ENST00000272369713299_329296.01109.3333333333333DNA
TgeneMEIS1chr2:11484121chr2:66775074ENST00000398506611299_329294.0464.0DNA
TgeneMEIS1chr2:11484122chr2:66775075ENST00000272369713299_329296.01109.3333333333333DNA
TgeneMEIS1chr2:11484122chr2:66775075ENST00000398506611299_329294.0464.0DNA


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneROCK2chr2:11484121chr2:66775074ENST00000315872-133373_42047.01389.0NPM1
HgeneROCK2chr2:11484122chr2:66775075ENST00000315872-133373_42047.01389.0NPM1
HgeneROCK2chr2:11484121chr2:66775074ENST00000315872-133363_78447.01389.0PPP1R12A
HgeneROCK2chr2:11484122chr2:66775075ENST00000315872-133363_78447.01389.0PPP1R12A


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ROCK2-MEIS1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ROCK2-MEIS1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource