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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ATG16L1-WAPAL (FusionGDB2 ID:7537)

Fusion Gene Summary for ATG16L1-WAPAL

check button Fusion gene summary
Fusion gene informationFusion gene name: ATG16L1-WAPAL
Fusion gene ID: 7537
HgeneTgene
Gene symbol

ATG16L1

WAPAL

Gene ID

55054

23063

Gene nameautophagy related 16 like 1WAPL cohesin release factor
SynonymsAPG16L|ATG16A|ATG16L|IBD10|WDR30FOE|KIAA0261|WAPAL
Cytomap

2q37.1

10q23.2

Type of geneprotein-codingprotein-coding
Descriptionautophagy-related protein 16-1APG16L betaATG16 autophagy related 16-like 1WD repeat domain 30wings apart-like protein homologfriend of EBNA2 (Epstein-Barr virus nuclear protein 2)friend of EBNA2 protein
Modification date2020032020200327
UniProtAcc

Q676U5

.
Ensembl transtripts involved in fusion geneENST00000498620, ENST00000347464, 
ENST00000373525, ENST00000392017, 
ENST00000392018, ENST00000392020, 
ENST00000263070, ENST00000298767, 
ENST00000372075, ENST00000484070, 
Fusion gene scores* DoF score5 X 4 X 4=804 X 3 X 4=48
# samples 55
** MAII scorelog2(5/80*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/48*10)=0.0588936890535686
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ATG16L1 [Title/Abstract] AND WAPAL [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATG16L1(234191399)-WAPAL(88206206), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ATG16L1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across WAPAL (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-BH-A18P-11AATG16L1chr2

234191399

+WAPALchr10

88206206

-


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Fusion Gene ORF analysis for ATG16L1-WAPAL

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000498620ENST00000263070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
3UTR-3CDSENST00000498620ENST00000298767ATG16L1chr2

234191399

+WAPALchr10

88206206

-
3UTR-3CDSENST00000498620ENST00000372075ATG16L1chr2

234191399

+WAPALchr10

88206206

-
3UTR-intronENST00000498620ENST00000484070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
5CDS-intronENST00000347464ENST00000484070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
5CDS-intronENST00000373525ENST00000484070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
5CDS-intronENST00000392017ENST00000484070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
5CDS-intronENST00000392018ENST00000484070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
5CDS-intronENST00000392020ENST00000484070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000347464ENST00000263070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000347464ENST00000298767ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000347464ENST00000372075ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000373525ENST00000263070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000373525ENST00000298767ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000373525ENST00000372075ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000392017ENST00000263070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000392017ENST00000298767ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000392017ENST00000372075ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000392018ENST00000263070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000392018ENST00000298767ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000392018ENST00000372075ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000392020ENST00000263070ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000392020ENST00000298767ATG16L1chr2

234191399

+WAPALchr10

88206206

-
In-frameENST00000392020ENST00000372075ATG16L1chr2

234191399

+WAPALchr10

88206206

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000347464ATG16L1chr2234191399+ENST00000298767WAPALchr1088206206-37179712571429390
ENST00000347464ATG16L1chr2234191399+ENST00000372075WAPALchr1088206206-19639712571429390
ENST00000347464ATG16L1chr2234191399+ENST00000263070WAPALchr1088206206-19609712571429390
ENST00000392017ATG16L1chr2234191399+ENST00000298767WAPALchr1088206206-420614602571918553
ENST00000392017ATG16L1chr2234191399+ENST00000372075WAPALchr1088206206-245214602571918553
ENST00000392017ATG16L1chr2234191399+ENST00000263070WAPALchr1088206206-244914602571918553
ENST00000373525ATG16L1chr2234191399+ENST00000298767WAPALchr1088206206-35688221561280374
ENST00000373525ATG16L1chr2234191399+ENST00000372075WAPALchr1088206206-18148221561280374
ENST00000373525ATG16L1chr2234191399+ENST00000263070WAPALchr1088206206-18118221561280374
ENST00000392020ATG16L1chr2234191399+ENST00000298767WAPALchr1088206206-401412681221726534
ENST00000392020ATG16L1chr2234191399+ENST00000372075WAPALchr1088206206-226012681221726534
ENST00000392020ATG16L1chr2234191399+ENST00000263070WAPALchr1088206206-225712681221726534
ENST00000392018ATG16L1chr2234191399+ENST00000298767WAPALchr1088206206-411413681141826570
ENST00000392018ATG16L1chr2234191399+ENST00000372075WAPALchr1088206206-236013681141826570
ENST00000392018ATG16L1chr2234191399+ENST00000263070WAPALchr1088206206-235713681141826570

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000347464ENST00000298767ATG16L1chr2234191399+WAPALchr1088206206-0.0002171930.99978286
ENST00000347464ENST00000372075ATG16L1chr2234191399+WAPALchr1088206206-0.0011495090.99885046
ENST00000347464ENST00000263070ATG16L1chr2234191399+WAPALchr1088206206-0.0011338710.9988662
ENST00000392017ENST00000298767ATG16L1chr2234191399+WAPALchr1088206206-0.0004663260.99953365
ENST00000392017ENST00000372075ATG16L1chr2234191399+WAPALchr1088206206-0.0040625890.99593747
ENST00000392017ENST00000263070ATG16L1chr2234191399+WAPALchr1088206206-0.0040242060.9959758
ENST00000373525ENST00000298767ATG16L1chr2234191399+WAPALchr1088206206-0.0002584510.9997415
ENST00000373525ENST00000372075ATG16L1chr2234191399+WAPALchr1088206206-0.0010639950.998936
ENST00000373525ENST00000263070ATG16L1chr2234191399+WAPALchr1088206206-0.0010499140.99895006
ENST00000392020ENST00000298767ATG16L1chr2234191399+WAPALchr1088206206-0.0003883360.9996117
ENST00000392020ENST00000372075ATG16L1chr2234191399+WAPALchr1088206206-0.0031699290.99683005
ENST00000392020ENST00000263070ATG16L1chr2234191399+WAPALchr1088206206-0.0031293340.9968707
ENST00000392018ENST00000298767ATG16L1chr2234191399+WAPALchr1088206206-0.0003571770.99964285
ENST00000392018ENST00000372075ATG16L1chr2234191399+WAPALchr1088206206-0.0032687110.9967313
ENST00000392018ENST00000263070ATG16L1chr2234191399+WAPALchr1088206206-0.0032345810.9967654

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Fusion Genomic Features for ATG16L1-WAPAL


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ATG16L1-WAPAL


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:234191399/chr10:88206206)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATG16L1

Q676U5

.
FUNCTION: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:24553140, PubMed:23376921, PubMed:24954904, PubMed:27273576, PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (PubMed:25645662). Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response (PubMed:24238340). Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway (PubMed:20637199). Plays a role in regulating morphology and function of Paneth cell (PubMed:18849966). {ECO:0000269|PubMed:18849966, ECO:0000269|PubMed:22749352, ECO:0000269|PubMed:23376921, ECO:0000269|PubMed:23392225, ECO:0000269|PubMed:24238340, ECO:0000269|PubMed:24553140, ECO:0000269|PubMed:24954904, ECO:0000269|PubMed:25645662, ECO:0000269|PubMed:27273576}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+81478_230238445.0Coiled coilOntology_term=ECO:0000255
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+121878_230401608.0Coiled coilOntology_term=ECO:0000255
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+111778_230382589.0Coiled coilOntology_term=ECO:0000255
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+1218296_299401608.0MotifNote=Caspase cleavage
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+1117296_299382589.0MotifNote=Caspase cleavage
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+814207_230238445.0RegionWIPI2-binding
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+1218207_230401608.0RegionWIPI2-binding
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+1218230_242401608.0RegionRB1CC1-binding
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+1117207_230382589.0RegionWIPI2-binding
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+1117230_242382589.0RegionRB1CC1-binding
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+1218320_359401608.0RepeatWD 1
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+1218364_403401608.0RepeatWD 2
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+1117320_359382589.0RepeatWD 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+91578_230222429.0Coiled coilOntology_term=ECO:0000255
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+814296_299238445.0MotifNote=Caspase cleavage
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+915296_299222429.0MotifNote=Caspase cleavage
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+814230_242238445.0RegionRB1CC1-binding
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+915207_230222429.0RegionWIPI2-binding
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+915230_242222429.0RegionRB1CC1-binding
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+814320_359238445.0RepeatWD 1
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+814364_403238445.0RepeatWD 2
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+814406_445238445.0RepeatWD 3
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+814447_484238445.0RepeatWD 4
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+814486_525238445.0RepeatWD 5
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+814532_573238445.0RepeatWD 6
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+814575_607238445.0RepeatWD 7
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+915320_359222429.0RepeatWD 1
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+915364_403222429.0RepeatWD 2
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+915406_445222429.0RepeatWD 3
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+915447_484222429.0RepeatWD 4
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+915486_525222429.0RepeatWD 5
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+915532_573222429.0RepeatWD 6
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+915575_607222429.0RepeatWD 7
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+1218406_445401608.0RepeatWD 3
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+1218447_484401608.0RepeatWD 4
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+1218486_525401608.0RepeatWD 5
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+1218532_573401608.0RepeatWD 6
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+1218575_607401608.0RepeatWD 7
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+1117364_403382589.0RepeatWD 2
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+1117406_445382589.0RepeatWD 3
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+1117447_484382589.0RepeatWD 4
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+1117486_525382589.0RepeatWD 5
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+1117532_573382589.0RepeatWD 6
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+1117575_607382589.0RepeatWD 7
TgeneWAPALchr2:234191399chr10:88206206ENST000002987671419260_28610381191.0Coiled coilOntology_term=ECO:0000255
TgeneWAPALchr2:234191399chr10:88206206ENST000002987671419749_78210381191.0Coiled coilOntology_term=ECO:0000255
TgeneWAPALchr2:234191399chr10:88206206ENST000002987671419626_116910381191.0DomainWAPL


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Fusion Gene Sequence for ATG16L1-WAPAL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>7537_7537_1_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000263070_length(transcript)=1960nt_BP=971nt
ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG
GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG
GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC
TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA
TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA
ACAGGCACGAGATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATG
ACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACGAGACGCTCTG
TCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCT
TCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGC
TTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTG
GATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGC
GGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAA
CAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACC
TCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGG
AAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTT
TTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACC
TTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACA
TTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGCATTTGCTAAATGACAGTTACTACATCA
ATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATA
CCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCA
CTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTT

>7537_7537_1_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000263070_length(amino acids)=390AA_BP=238
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV
EQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD
RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG
EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK

--------------------------------------------------------------
>7537_7537_2_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000298767_length(transcript)=3717nt_BP=971nt
ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG
GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG
GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC
TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA
TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA
ACAGGCACGAGATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATG
ACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACGAGACGCTCTG
TCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCT
TCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGC
TTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTG
GATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGC
GGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAA
CAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACC
TCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGG
AAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTT
TTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACC
TTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACA
TTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGCATTTGCTAAATGACAGTTACTACATCA
ATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATA
CCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCA
CTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTT
TTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTTAATAATTTTGTGAATTTTTTGGTTGTTGTTC
CCTGAACTACTGTCTATATTTAAAATTAGATGGAATCCAAAGATACACGGGATTAATAGTATATTTTTTTATTCTTGATTAGGTTTGGGT
TATTGAACTATTTTTTACTTTTGAGACCACAACCATATTCAATATCATACCATAATGTGTCATAGCTATAGGCACAAGAAAAACAACAGT
TTGAGAGAATATTATATAAGATGATGTGCCCTGTTAAAAGGAGGAGGCAAAATAGTCAAACCCAGGGTAGTTTACACTTAATGCTAGGGA
GGCTCTTAAAACATTATTAGATTTTGAGGAAAGACTCTCTAGATATATTTTCTAATGTTCAGTACAATAAATATAAGGAAGCTAAAACAC
CAATGTGGAATTCCTGTTTCCAGATAACATGTATATTCTTCTATAGAGTGACAGGATCAATTGCATAAGCGCAAAGCCTTAAATTGCTGG
TTTAGAGAAGACCCTTTTTTCATTCAGATTCTTTGTTCGTAGAGCAGTTATTTGAAAAACAGTTATGGAACACAAAACATTTTATAGATT
TAATATCATAACATTGCAAATTTTTCTTGTATTATTCACACCACTGGTTATACTTTTTTTTTTCCTTTTTTATTGATTGGGCCTGAATAC
AGGCTTTCTAGAGATCTTTTTCATTAATACTTTTAAATACCTTTCAGGTAGTTACATCATGTTTCTTCATTGGATTTGTAAAACTTGAAG
CCATAAAAATATTAGTTTGGTGTGTATTGGGGAAAATAGCTAAAAGTCTAATTTTTACCCATTTAGACTTTGTTATTTCCTTGTATAAAG
TGACAAATCGGGGCTCTTGTATCAGTGCCAGCTGTAATGTTTTTAAATGCAGTGGCTGCCTTCTATTGTCTTCCTATTTTTGATAATGCA
GATTGTTGGGAAATCTGTAAGGAAGTAACTGATTCCAGGCAAATTGTTTTCTTCCTTCTACCCACCCCAACCCCTACCCATCACCTTTTA
AGAACATAGTACGCCAGTGTAACGTGGGAACCATTGAGATTGTATTTGCCCTGAGTATTAAAGCTAGCTTAGCAAAATACTTTTAAAAAC
ATATTGGTAAATGATACCCGTAAAATTAAATTAGTTATATTTTATTTTAAAATGCAAAATACATTGATATTTATTAATCATTGGATTTAG
GGAAAGGGACAGATTTTTGGTGAACCTGACTTGTGGCAGATGGTAAGGAATATTATAAAACATTTGGATGAGAACAATCAGGGCGAACTG
CATTTTTCTGTTACACTGGTAATCATTTGAAAATTGATTTACCTCAGTGTTTAACAGTTTTTTGTTTTGTTTTGTTTTTTAAATAATAAC
TAATTGTCGAGCACTGATAGAGATGCAGATTTTGGTGGGGGGAGGTGGTGGGGGAGATAATCACTTCACCAACTGCAGTGCATTTGTGTG
TTTTTAACCCTCAGAGAACTCTGCATTTTAGGGTACTTGAGGCTGACTTAACTAAAAGTTTTAAAGTAACCTTTTTTCCATTGTAAATAT
TTCTGTAAATACTACCAATTGGAAATTAGAACAGTAGAGTACTTTTCTGAATCCAATCCTATTTTTATTTTATACAGTATTTCTCAGCTG
TGATCTTTGGAGCAAAAGCCAACGGCAGGAAAAAATAGTTTGTACCAGTTTCATGAAGTATGTCTTTGGGTTTTTGTAAATAATTTTAAC

>7537_7537_2_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000298767_length(amino acids)=390AA_BP=238
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV
EQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD
RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG
EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK

--------------------------------------------------------------
>7537_7537_3_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000372075_length(transcript)=1963nt_BP=971nt
ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG
GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG
GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC
TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA
TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA
ACAGGCACGAGATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATG
ACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACGAGACGCTCTG
TCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCT
TCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGC
TTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTG
GATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGC
GGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAA
CAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACC
TCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGG
AAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTT
TTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACC
TTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACA
TTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGCATTTGCTAAATGACAGTTACTACATCA
ATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATA
CCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCA
CTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTT

>7537_7537_3_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000372075_length(amino acids)=390AA_BP=238
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV
EQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD
RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG
EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK

--------------------------------------------------------------
>7537_7537_4_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000263070_length(transcript)=1811nt_BP=822nt
AAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATG
CTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCT
GACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAG
TATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAG
ATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTC
ATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCT
GGAGGCCTTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCT
GGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCA
GGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGAT
TATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACT
CAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACAT
AAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTAC
ACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATA
ATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATT
GAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCAT
GAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATT
CGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTA
TTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGC
TGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTG
AGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTT

>7537_7537_4_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000263070_length(amino acids)=374AA_BP=222
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV
EQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGE
VNAVQFSPGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEK
TDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTG

--------------------------------------------------------------
>7537_7537_5_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000298767_length(transcript)=3568nt_BP=822nt
AAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATG
CTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCT
GACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAG
TATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAG
ATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTC
ATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCT
GGAGGCCTTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCT
GGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCA
GGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGAT
TATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACT
CAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACAT
AAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTAC
ACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATA
ATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATT
GAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCAT
GAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATT
CGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTA
TTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGC
TGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTG
AGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTT
AATAATTTTGTGAATTTTTTGGTTGTTGTTCCCTGAACTACTGTCTATATTTAAAATTAGATGGAATCCAAAGATACACGGGATTAATAG
TATATTTTTTTATTCTTGATTAGGTTTGGGTTATTGAACTATTTTTTACTTTTGAGACCACAACCATATTCAATATCATACCATAATGTG
TCATAGCTATAGGCACAAGAAAAACAACAGTTTGAGAGAATATTATATAAGATGATGTGCCCTGTTAAAAGGAGGAGGCAAAATAGTCAA
ACCCAGGGTAGTTTACACTTAATGCTAGGGAGGCTCTTAAAACATTATTAGATTTTGAGGAAAGACTCTCTAGATATATTTTCTAATGTT
CAGTACAATAAATATAAGGAAGCTAAAACACCAATGTGGAATTCCTGTTTCCAGATAACATGTATATTCTTCTATAGAGTGACAGGATCA
ATTGCATAAGCGCAAAGCCTTAAATTGCTGGTTTAGAGAAGACCCTTTTTTCATTCAGATTCTTTGTTCGTAGAGCAGTTATTTGAAAAA
CAGTTATGGAACACAAAACATTTTATAGATTTAATATCATAACATTGCAAATTTTTCTTGTATTATTCACACCACTGGTTATACTTTTTT
TTTTCCTTTTTTATTGATTGGGCCTGAATACAGGCTTTCTAGAGATCTTTTTCATTAATACTTTTAAATACCTTTCAGGTAGTTACATCA
TGTTTCTTCATTGGATTTGTAAAACTTGAAGCCATAAAAATATTAGTTTGGTGTGTATTGGGGAAAATAGCTAAAAGTCTAATTTTTACC
CATTTAGACTTTGTTATTTCCTTGTATAAAGTGACAAATCGGGGCTCTTGTATCAGTGCCAGCTGTAATGTTTTTAAATGCAGTGGCTGC
CTTCTATTGTCTTCCTATTTTTGATAATGCAGATTGTTGGGAAATCTGTAAGGAAGTAACTGATTCCAGGCAAATTGTTTTCTTCCTTCT
ACCCACCCCAACCCCTACCCATCACCTTTTAAGAACATAGTACGCCAGTGTAACGTGGGAACCATTGAGATTGTATTTGCCCTGAGTATT
AAAGCTAGCTTAGCAAAATACTTTTAAAAACATATTGGTAAATGATACCCGTAAAATTAAATTAGTTATATTTTATTTTAAAATGCAAAA
TACATTGATATTTATTAATCATTGGATTTAGGGAAAGGGACAGATTTTTGGTGAACCTGACTTGTGGCAGATGGTAAGGAATATTATAAA
ACATTTGGATGAGAACAATCAGGGCGAACTGCATTTTTCTGTTACACTGGTAATCATTTGAAAATTGATTTACCTCAGTGTTTAACAGTT
TTTTGTTTTGTTTTGTTTTTTAAATAATAACTAATTGTCGAGCACTGATAGAGATGCAGATTTTGGTGGGGGGAGGTGGTGGGGGAGATA
ATCACTTCACCAACTGCAGTGCATTTGTGTGTTTTTAACCCTCAGAGAACTCTGCATTTTAGGGTACTTGAGGCTGACTTAACTAAAAGT
TTTAAAGTAACCTTTTTTCCATTGTAAATATTTCTGTAAATACTACCAATTGGAAATTAGAACAGTAGAGTACTTTTCTGAATCCAATCC
TATTTTTATTTTATACAGTATTTCTCAGCTGTGATCTTTGGAGCAAAAGCCAACGGCAGGAAAAAATAGTTTGTACCAGTTTCATGAAGT

>7537_7537_5_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000298767_length(amino acids)=374AA_BP=222
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV
EQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGE
VNAVQFSPGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEK
TDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTG

--------------------------------------------------------------
>7537_7537_6_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000372075_length(transcript)=1814nt_BP=822nt
AAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATG
CTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCT
GACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAG
TATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAG
ATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTC
ATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCT
GGAGGCCTTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCT
GGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCA
GGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGAT
TATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACT
CAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACAT
AAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTAC
ACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATA
ATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATT
GAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCAT
GAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATT
CGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTA
TTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGC
TGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTG
AGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTT

>7537_7537_6_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000372075_length(amino acids)=374AA_BP=222
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV
EQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGE
VNAVQFSPGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEK
TDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTG

--------------------------------------------------------------
>7537_7537_7_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000263070_length(transcript)=2449nt_BP=1460nt
ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG
GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG
GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC
TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA
TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA
ACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGG
AACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGC
AGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACC
TTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGG
AAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGA
GGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGG
ATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCC
TTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTG
GTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCC
GGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCA
GTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTG
TGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTC
CCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAG
AGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGG
CCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACT
TTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTA
GAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGT
CAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGT
CATGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCC
ATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATT
TGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGA
ATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATA

>7537_7537_7_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000263070_length(amino acids)=553AA_BP=401
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI
KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ
PAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG
SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKT
DGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQ

--------------------------------------------------------------
>7537_7537_8_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000298767_length(transcript)=4206nt_BP=1460nt
ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG
GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG
GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC
TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA
TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA
ACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGG
AACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGC
AGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACC
TTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGG
AAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGA
GGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGG
ATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCC
TTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTG
GTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCC
GGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCA
GTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTG
TGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTC
CCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAG
AGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGG
CCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACT
TTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTA
GAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGT
CAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGT
CATGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCC
ATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATT
TGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGA
ATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATA
AAGCTTTTAATAATTTTGTGAATTTTTTGGTTGTTGTTCCCTGAACTACTGTCTATATTTAAAATTAGATGGAATCCAAAGATACACGGG
ATTAATAGTATATTTTTTTATTCTTGATTAGGTTTGGGTTATTGAACTATTTTTTACTTTTGAGACCACAACCATATTCAATATCATACC
ATAATGTGTCATAGCTATAGGCACAAGAAAAACAACAGTTTGAGAGAATATTATATAAGATGATGTGCCCTGTTAAAAGGAGGAGGCAAA
ATAGTCAAACCCAGGGTAGTTTACACTTAATGCTAGGGAGGCTCTTAAAACATTATTAGATTTTGAGGAAAGACTCTCTAGATATATTTT
CTAATGTTCAGTACAATAAATATAAGGAAGCTAAAACACCAATGTGGAATTCCTGTTTCCAGATAACATGTATATTCTTCTATAGAGTGA
CAGGATCAATTGCATAAGCGCAAAGCCTTAAATTGCTGGTTTAGAGAAGACCCTTTTTTCATTCAGATTCTTTGTTCGTAGAGCAGTTAT
TTGAAAAACAGTTATGGAACACAAAACATTTTATAGATTTAATATCATAACATTGCAAATTTTTCTTGTATTATTCACACCACTGGTTAT
ACTTTTTTTTTTCCTTTTTTATTGATTGGGCCTGAATACAGGCTTTCTAGAGATCTTTTTCATTAATACTTTTAAATACCTTTCAGGTAG
TTACATCATGTTTCTTCATTGGATTTGTAAAACTTGAAGCCATAAAAATATTAGTTTGGTGTGTATTGGGGAAAATAGCTAAAAGTCTAA
TTTTTACCCATTTAGACTTTGTTATTTCCTTGTATAAAGTGACAAATCGGGGCTCTTGTATCAGTGCCAGCTGTAATGTTTTTAAATGCA
GTGGCTGCCTTCTATTGTCTTCCTATTTTTGATAATGCAGATTGTTGGGAAATCTGTAAGGAAGTAACTGATTCCAGGCAAATTGTTTTC
TTCCTTCTACCCACCCCAACCCCTACCCATCACCTTTTAAGAACATAGTACGCCAGTGTAACGTGGGAACCATTGAGATTGTATTTGCCC
TGAGTATTAAAGCTAGCTTAGCAAAATACTTTTAAAAACATATTGGTAAATGATACCCGTAAAATTAAATTAGTTATATTTTATTTTAAA
ATGCAAAATACATTGATATTTATTAATCATTGGATTTAGGGAAAGGGACAGATTTTTGGTGAACCTGACTTGTGGCAGATGGTAAGGAAT
ATTATAAAACATTTGGATGAGAACAATCAGGGCGAACTGCATTTTTCTGTTACACTGGTAATCATTTGAAAATTGATTTACCTCAGTGTT
TAACAGTTTTTTGTTTTGTTTTGTTTTTTAAATAATAACTAATTGTCGAGCACTGATAGAGATGCAGATTTTGGTGGGGGGAGGTGGTGG
GGGAGATAATCACTTCACCAACTGCAGTGCATTTGTGTGTTTTTAACCCTCAGAGAACTCTGCATTTTAGGGTACTTGAGGCTGACTTAA
CTAAAAGTTTTAAAGTAACCTTTTTTCCATTGTAAATATTTCTGTAAATACTACCAATTGGAAATTAGAACAGTAGAGTACTTTTCTGAA
TCCAATCCTATTTTTATTTTATACAGTATTTCTCAGCTGTGATCTTTGGAGCAAAAGCCAACGGCAGGAAAAAATAGTTTGTACCAGTTT

>7537_7537_8_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000298767_length(amino acids)=553AA_BP=401
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI
KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ
PAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG
SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKT
DGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQ

--------------------------------------------------------------
>7537_7537_9_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000372075_length(transcript)=2452nt_BP=1460nt
ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG
GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG
GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC
TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA
TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA
ACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGG
AACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGC
AGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACC
TTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGG
AAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGA
GGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGG
ATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCC
TTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTG
GTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCC
GGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCA
GTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTG
TGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTC
CCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAG
AGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGG
CCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACT
TTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTA
GAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGT
CAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGT
CATGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCC
ATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATT
TGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGA
ATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATA

>7537_7537_9_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000372075_length(amino acids)=553AA_BP=401
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI
KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ
PAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG
SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKT
DGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQ

--------------------------------------------------------------
>7537_7537_10_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000263070_length(transcript)=2357nt_BP=1368nt
GTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGC
TGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGG
CGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTG
GCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTA
CAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGAC
CTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAG
ACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACT
TTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCC
AATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTA
CCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGA
GCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCCTTCTGGATTCTATCACTAATATCTTTGGTCTGTCCGAGTCTCCCCTTTTGGGA
CATCATTCTTCTTCTGATGCTGCCAGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGT
AAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGG
TTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGT
AATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTG
GATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCC
ACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAG
AAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCC
TCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTT
TCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGA
GTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCA
AGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCA
TGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCAT
GCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTG
TGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAAT
GTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAA

>7537_7537_10_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000263070_length(amino acids)=570AA_BP=418
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI
KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ
PAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD
RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG
EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK

--------------------------------------------------------------
>7537_7537_11_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000298767_length(transcript)=4114nt_BP=1368nt
GTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGC
TGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGG
CGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTG
GCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTA
CAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGAC
CTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAG
ACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACT
TTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCC
AATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTA
CCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGA
GCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCCTTCTGGATTCTATCACTAATATCTTTGGTCTGTCCGAGTCTCCCCTTTTGGGA
CATCATTCTTCTTCTGATGCTGCCAGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGT
AAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGG
TTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGT
AATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTG
GATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCC
ACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAG
AAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCC
TCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTT
TCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGA
GTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCA
AGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCA
TGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCAT
GCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTG
TGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAAT
GTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAA
GCTTTTAATAATTTTGTGAATTTTTTGGTTGTTGTTCCCTGAACTACTGTCTATATTTAAAATTAGATGGAATCCAAAGATACACGGGAT
TAATAGTATATTTTTTTATTCTTGATTAGGTTTGGGTTATTGAACTATTTTTTACTTTTGAGACCACAACCATATTCAATATCATACCAT
AATGTGTCATAGCTATAGGCACAAGAAAAACAACAGTTTGAGAGAATATTATATAAGATGATGTGCCCTGTTAAAAGGAGGAGGCAAAAT
AGTCAAACCCAGGGTAGTTTACACTTAATGCTAGGGAGGCTCTTAAAACATTATTAGATTTTGAGGAAAGACTCTCTAGATATATTTTCT
AATGTTCAGTACAATAAATATAAGGAAGCTAAAACACCAATGTGGAATTCCTGTTTCCAGATAACATGTATATTCTTCTATAGAGTGACA
GGATCAATTGCATAAGCGCAAAGCCTTAAATTGCTGGTTTAGAGAAGACCCTTTTTTCATTCAGATTCTTTGTTCGTAGAGCAGTTATTT
GAAAAACAGTTATGGAACACAAAACATTTTATAGATTTAATATCATAACATTGCAAATTTTTCTTGTATTATTCACACCACTGGTTATAC
TTTTTTTTTTCCTTTTTTATTGATTGGGCCTGAATACAGGCTTTCTAGAGATCTTTTTCATTAATACTTTTAAATACCTTTCAGGTAGTT
ACATCATGTTTCTTCATTGGATTTGTAAAACTTGAAGCCATAAAAATATTAGTTTGGTGTGTATTGGGGAAAATAGCTAAAAGTCTAATT
TTTACCCATTTAGACTTTGTTATTTCCTTGTATAAAGTGACAAATCGGGGCTCTTGTATCAGTGCCAGCTGTAATGTTTTTAAATGCAGT
GGCTGCCTTCTATTGTCTTCCTATTTTTGATAATGCAGATTGTTGGGAAATCTGTAAGGAAGTAACTGATTCCAGGCAAATTGTTTTCTT
CCTTCTACCCACCCCAACCCCTACCCATCACCTTTTAAGAACATAGTACGCCAGTGTAACGTGGGAACCATTGAGATTGTATTTGCCCTG
AGTATTAAAGCTAGCTTAGCAAAATACTTTTAAAAACATATTGGTAAATGATACCCGTAAAATTAAATTAGTTATATTTTATTTTAAAAT
GCAAAATACATTGATATTTATTAATCATTGGATTTAGGGAAAGGGACAGATTTTTGGTGAACCTGACTTGTGGCAGATGGTAAGGAATAT
TATAAAACATTTGGATGAGAACAATCAGGGCGAACTGCATTTTTCTGTTACACTGGTAATCATTTGAAAATTGATTTACCTCAGTGTTTA
ACAGTTTTTTGTTTTGTTTTGTTTTTTAAATAATAACTAATTGTCGAGCACTGATAGAGATGCAGATTTTGGTGGGGGGAGGTGGTGGGG
GAGATAATCACTTCACCAACTGCAGTGCATTTGTGTGTTTTTAACCCTCAGAGAACTCTGCATTTTAGGGTACTTGAGGCTGACTTAACT
AAAAGTTTTAAAGTAACCTTTTTTCCATTGTAAATATTTCTGTAAATACTACCAATTGGAAATTAGAACAGTAGAGTACTTTTCTGAATC
CAATCCTATTTTTATTTTATACAGTATTTCTCAGCTGTGATCTTTGGAGCAAAAGCCAACGGCAGGAAAAAATAGTTTGTACCAGTTTCA

>7537_7537_11_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000298767_length(amino acids)=570AA_BP=418
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI
KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ
PAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD
RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG
EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK

--------------------------------------------------------------
>7537_7537_12_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000372075_length(transcript)=2360nt_BP=1368nt
GTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGC
TGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGG
CGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTG
GCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTA
CAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGAC
CTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAG
ACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACT
TTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCC
AATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTA
CCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGA
GCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCCTTCTGGATTCTATCACTAATATCTTTGGTCTGTCCGAGTCTCCCCTTTTGGGA
CATCATTCTTCTTCTGATGCTGCCAGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGT
AAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGG
TTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGT
AATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTG
GATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCC
ACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAG
AAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCC
TCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTT
TCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGA
GTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCA
AGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCA
TGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCAT
GCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTG
TGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAAT
GTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAA

>7537_7537_12_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000372075_length(amino acids)=570AA_BP=418
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI
KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ
PAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD
RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG
EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK

--------------------------------------------------------------
>7537_7537_13_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000263070_length(transcript)=2257nt_BP=1268nt
GTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATT
GGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGC
AACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATT
CAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACA
ATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGG
TGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTG
ACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGC
AGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCC
AGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGG
AACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCA
TCAGCAGAGCAGCCACGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGA
GGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCA
CTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAA
TTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATC
GATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGC
ATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGA
AGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAG
CACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGA
CAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAAT
ATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAA
GAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGC
ATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTA
AATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTT
AGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGA
CATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTTAATA

>7537_7537_13_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000263070_length(amino acids)=534AA_BP=382
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI
KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVS
SFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS
YLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLN

--------------------------------------------------------------
>7537_7537_14_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000298767_length(transcript)=4014nt_BP=1268nt
GTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATT
GGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGC
AACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATT
CAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACA
ATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGG
TGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTG
ACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGC
AGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCC
AGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGG
AACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCA
TCAGCAGAGCAGCCACGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGA
GGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCA
CTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAA
TTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATC
GATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGC
ATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGA
AGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAG
CACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGA
CAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAAT
ATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAA
GAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGC
ATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTA
AATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTT
AGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGA
CATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTTAATA
ATTTTGTGAATTTTTTGGTTGTTGTTCCCTGAACTACTGTCTATATTTAAAATTAGATGGAATCCAAAGATACACGGGATTAATAGTATA
TTTTTTTATTCTTGATTAGGTTTGGGTTATTGAACTATTTTTTACTTTTGAGACCACAACCATATTCAATATCATACCATAATGTGTCAT
AGCTATAGGCACAAGAAAAACAACAGTTTGAGAGAATATTATATAAGATGATGTGCCCTGTTAAAAGGAGGAGGCAAAATAGTCAAACCC
AGGGTAGTTTACACTTAATGCTAGGGAGGCTCTTAAAACATTATTAGATTTTGAGGAAAGACTCTCTAGATATATTTTCTAATGTTCAGT
ACAATAAATATAAGGAAGCTAAAACACCAATGTGGAATTCCTGTTTCCAGATAACATGTATATTCTTCTATAGAGTGACAGGATCAATTG
CATAAGCGCAAAGCCTTAAATTGCTGGTTTAGAGAAGACCCTTTTTTCATTCAGATTCTTTGTTCGTAGAGCAGTTATTTGAAAAACAGT
TATGGAACACAAAACATTTTATAGATTTAATATCATAACATTGCAAATTTTTCTTGTATTATTCACACCACTGGTTATACTTTTTTTTTT
CCTTTTTTATTGATTGGGCCTGAATACAGGCTTTCTAGAGATCTTTTTCATTAATACTTTTAAATACCTTTCAGGTAGTTACATCATGTT
TCTTCATTGGATTTGTAAAACTTGAAGCCATAAAAATATTAGTTTGGTGTGTATTGGGGAAAATAGCTAAAAGTCTAATTTTTACCCATT
TAGACTTTGTTATTTCCTTGTATAAAGTGACAAATCGGGGCTCTTGTATCAGTGCCAGCTGTAATGTTTTTAAATGCAGTGGCTGCCTTC
TATTGTCTTCCTATTTTTGATAATGCAGATTGTTGGGAAATCTGTAAGGAAGTAACTGATTCCAGGCAAATTGTTTTCTTCCTTCTACCC
ACCCCAACCCCTACCCATCACCTTTTAAGAACATAGTACGCCAGTGTAACGTGGGAACCATTGAGATTGTATTTGCCCTGAGTATTAAAG
CTAGCTTAGCAAAATACTTTTAAAAACATATTGGTAAATGATACCCGTAAAATTAAATTAGTTATATTTTATTTTAAAATGCAAAATACA
TTGATATTTATTAATCATTGGATTTAGGGAAAGGGACAGATTTTTGGTGAACCTGACTTGTGGCAGATGGTAAGGAATATTATAAAACAT
TTGGATGAGAACAATCAGGGCGAACTGCATTTTTCTGTTACACTGGTAATCATTTGAAAATTGATTTACCTCAGTGTTTAACAGTTTTTT
GTTTTGTTTTGTTTTTTAAATAATAACTAATTGTCGAGCACTGATAGAGATGCAGATTTTGGTGGGGGGAGGTGGTGGGGGAGATAATCA
CTTCACCAACTGCAGTGCATTTGTGTGTTTTTAACCCTCAGAGAACTCTGCATTTTAGGGTACTTGAGGCTGACTTAACTAAAAGTTTTA
AAGTAACCTTTTTTCCATTGTAAATATTTCTGTAAATACTACCAATTGGAAATTAGAACAGTAGAGTACTTTTCTGAATCCAATCCTATT
TTTATTTTATACAGTATTTCTCAGCTGTGATCTTTGGAGCAAAAGCCAACGGCAGGAAAAAATAGTTTGTACCAGTTTCATGAAGTATGT

>7537_7537_14_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000298767_length(amino acids)=534AA_BP=382
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI
KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVS
SFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS
YLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLN

--------------------------------------------------------------
>7537_7537_15_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000372075_length(transcript)=2260nt_BP=1268nt
GTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATT
GGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGC
AACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATT
CAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACA
ATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGG
TGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTG
ACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGC
AGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCC
AGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGG
AACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCA
TCAGCAGAGCAGCCACGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGA
GGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCA
CTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAA
TTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATC
GATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGC
ATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGA
AGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAG
CACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGA
CAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAAT
ATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAA
GAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGC
ATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTA
AATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTT
AGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGA
CATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTTAATA

>7537_7537_15_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000372075_length(amino acids)=534AA_BP=382
MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI
KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVS
SFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS
YLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLN

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Fusion Gene PPI Analysis for ATG16L1-WAPAL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneATG16L1chr2:234191399chr10:88206206ENST00000347464+81413_43238.0445.0ATG5
HgeneATG16L1chr2:234191399chr10:88206206ENST00000373525+91513_43222.0429.0ATG5
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392017+121813_43401.0608.0ATG5
HgeneATG16L1chr2:234191399chr10:88206206ENST00000392020+111713_43382.0589.0ATG5


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATG16L1-WAPAL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATG16L1-WAPAL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource