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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:RPL10-PGK1 (FusionGDB2 ID:75807)

Fusion Gene Summary for RPL10-PGK1

Fusion gene summary

Fusion gene information	Fusion gene name: RPL10-PGK1
	Fusion gene ID: 75807
		Hgene	Tgene
	Gene symbol	RPL10	PGK1
	Gene ID	6138	5230
	Gene name	ribosomal protein L15	phosphoglycerate kinase 1
	Synonyms	DBA12\|EC45\|L15\|RPL10\|RPLY10\|RPYL10	HEL-S-68p\|MIG10\|PGKA
	Cytomap	3p24.2	Xq21.1
	Type of gene	protein-coding	protein-coding
	Description	60S ribosomal protein L15large ribosomal subunit protein eL15	phosphoglycerate kinase 1PRP 2cell migration-inducing gene 10 proteinepididymis secretory sperm binding protein Li 68pprimer recognition protein 2
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000369817, ENST00000406022, ENST00000424325, ENST00000479366,	ENST00000442431, ENST00000476531, ENST00000537456, ENST00000373316,
Fusion gene scores	* DoF score	11 X 12 X 7=924	13 X 12 X 6=936
	# samples	17	14
	** MAII score	log2(17/924*10)=-2.44235810527836 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(14/936*10)=-2.74108170263844 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: RPL10 [Title/Abstract] AND PGK1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	RPL10(153628282)-PGK1(77369512), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	PGK1	GO:0071456	cellular response to hypoxia	11130727

Fusion gene breakpoints across RPL10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PGK1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	Non-Cancer	TCGA-HU-A4G3-11A	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+

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Fusion Gene ORF analysis for RPL10-PGK1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000369817	ENST00000442431	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
5CDS-intron	ENST00000369817	ENST00000476531	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
5CDS-intron	ENST00000369817	ENST00000537456	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
5CDS-intron	ENST00000406022	ENST00000442431	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
5CDS-intron	ENST00000406022	ENST00000476531	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
5CDS-intron	ENST00000406022	ENST00000537456	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
5CDS-intron	ENST00000424325	ENST00000442431	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
5CDS-intron	ENST00000424325	ENST00000476531	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
5CDS-intron	ENST00000424325	ENST00000537456	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
In-frame	ENST00000369817	ENST00000373316	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
In-frame	ENST00000406022	ENST00000373316	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
In-frame	ENST00000424325	ENST00000373316	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
intron-3CDS	ENST00000479366	ENST00000373316	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
intron-intron	ENST00000479366	ENST00000442431	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
intron-intron	ENST00000479366	ENST00000476531	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+
intron-intron	ENST00000479366	ENST00000537456	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

ENST00000369817

RPL10

chrX

153628282

ENST00000373316

PGK1

chrX

77369512

5353

905

441

1886

481

ENST00000424325

RPL10

chrX

153628282

ENST00000373316

PGK1

chrX

77369512

4965

517

1498

481

ENST00000406022

RPL10

chrX

153628282

ENST00000373316

PGK1

chrX

77369512

4825

377

153

1358

401

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000369817	ENST00000373316	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+	0.000270826	0.9997292
ENST00000424325	ENST00000373316	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+	0.000271928	0.999728
ENST00000406022	ENST00000373316	RPL10	chrX	153628282	+	PGK1	chrX	77369512	+	0.000201482	0.9997986

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Fusion Genomic Features for RPL10-PGK1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
RPL10	chrX	153628282	+	PGK1	chrX	77369512	+	4.01E-05	0.9999598
RPL10	chrX	153628282	+	PGK1	chrX	77369512	+	4.01E-05	0.9999598

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RPL10-PGK1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:153628282/chrX:77369512)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

PGK1

chrX:153628282

chrX:77369512

ENST00000373316

373_376

418.0

Nucleotide binding

ATP

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

PGK1

chrX:153628282

chrX:77369512

ENST00000373316

24_26

418.0

Region

Substrate binding

Tgene

PGK1

chrX:153628282

chrX:77369512

ENST00000373316

63_66

418.0

Region

Substrate binding

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Fusion Gene Sequence for RPL10-PGK1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>75807_75807_1_RPL10-PGK1_RPL10_chrX_153628282_ENST00000369817_PGK1_chrX_77369512_ENST00000373316_length(transcript)=5353nt_BP=905nt
GCAATTCCTGACTTGTACTGCCCCAGTGGTGTTACAGCCTCGAACCCAGTTTCCAGACCTAAGTCACCGCCGGCATCCAGAGTCCCATGA
TGGAAAGGGAGGCTAGGTTCCCCTGGGAAGGACCTTGCACCACTGCTGCAAGTGCACCCCAGAAATCGTCCCAAGCTTTTCTCAAAGGGA
CCTGCAGCCATTTATAAAAGCGACATATCATCCTGGAAAACAGAAATATACGTCTGTCACAGTTAACGGCAAAGCCTAGGGCAAGAGTTC
TACGCCCAAGATGGCCAGCCGGAAGCGGGCTTCTCGCGACCATGTGGCGAAGCCCCATTCGTCAGCTGGCCGCCCGCGGCCCTGGTACCC
GGTCACCTCTCTGATCTGCGCATGTGCTGGGCTACGCCCGGGCGCAAGCGCCAAGAGCGGCTGCGTCTATGGTCATGACGTCTGACAGAG
CGTCCACCCGTCTTCGACAGGACTCTATGGTTCTTACGCGCGCAGACAGACCGCCTATATAAGCCATGCGCAGGCGGAGGAGCGCCTCTT
TCCCTTCGGTGTGCCACTGAAGATCCTGGTGTCGCCATGGGCCGCCGCCCCGCCCGTTGTTACCGGTATTGTAAGAACAAGCCGTACCCA
AAGTCTCGCTTCTGCCGAGGTGTCCCTGATGCCAAGATTCGCATTTTTGACCTGGGGCGGAAAAAGGCAAAAGTGGATGAGTTTCCGCTT
TGTGGCCACATGGTGTCAGATGAATATGAGCAGCTGTCCTCTGAAGCCCTGGAGGCTGCCCGAATTTGTGCCAATAAGTACATGGTAAAA
AGTTGTGGCAAAGATGGCTTCCATATCCGGGTGCGGCTCCACCCCTTCCACGTCATCCGCATCAACAAGATGTTGTCCTGTGCTGGGGCT
GACAGGGATGTTCTGTTCTTGAAGGACTGTGTAGGCCCAGAAGTGGAGAAAGCCTGTGCCAACCCAGCTGCTGGGTCTGTCATCCTGCTG
GAGAACCTCCGCTTTCATGTGGAGGAAGAAGGGAAGGGAAAAGATGCTTCTGGGAACAAGGTTAAAGCCGAGCCAGCCAAAATAGAAGCT
TTCCGAGCTTCACTTTCCAAGCTAGGGGATGTCTATGTCAATGATGCTTTTGGCACTGCTCACAGAGCCCACAGCTCCATGGTAGGAGTC
AATCTGCCACAGAAGGCTGGTGGGTTTTTGATGAAGAAGGAGCTGAACTACTTTGCAAAGGCCTTGGAGAGCCCAGAGCGACCCTTCCTG
GCCATCCTGGGCGGAGCTAAAGTTGCAGACAAGATCCAGCTCATCAATAATATGCTGGACAAAGTCAATGAGATGATTATTGGTGGTGGA
ATGGCTTTTACCTTCCTTAAGGTGCTCAACAACATGGAGATTGGCACTTCTCTGTTTGATGAAGAGGGAGCCAAGATTGTCAAAGACCTA
ATGTCCAAAGCTGAGAAGAATGGTGTGAAGATTACCTTGCCTGTTGACTTTGTCACTGCTGACAAGTTTGATGAGAATGCCAAGACTGGC
CAAGCCACTGTGGCTTCTGGCATACCTGCTGGCTGGATGGGCTTGGACTGTGGTCCTGAAAGCAGCAAGAAGTATGCTGAGGCTGTCACT
CGGGCTAAGCAGATTGTGTGGAATGGTCCTGTGGGGGTATTTGAATGGGAAGCTTTTGCCCGGGGAACCAAAGCTCTCATGGATGAGGTG
GTGAAAGCCACTTCTAGGGGCTGCATCACCATCATAGGTGGTGGAGACACTGCCACTTGCTGTGCCAAATGGAACACGGAGGATAAAGTC
AGCCATGTGAGCACTGGGGGTGGTGCCAGTTTGGAGCTCCTGGAAGGTAAAGTCCTTCCTGGGGTGGATGCTCTCAGCAATATTTAGTAC
TTTCCTGCCTTTTAGTTCCTGTGCACAGCCCCTAAGTCAACTTAGCATTTTCTGCATCTCCACTTGGCATTAGCTAAAACCTTCCATGTC
AAGATTCAGCTAGTGGCCAAGAGATGCAGTGCCAGGAACCCTTAAACAGTTGCACAGCATCTCAGCTCATCTTCACTGCACCCTGGATTT
GCATACATTCTTCAAGATCCCATTTGAATTTTTTAGTGACTAAACCATTGTGCATTCTAGAGTGCATATATTTATATTTTGCCTGTTAAA
AAGAAAGTGAGCAGTGTTAGCTTAGTTCTCTTTTGATGTAGGTTATTATGATTAGCTTTGTCACTGTTTCACTACTCAGCATGGAAACAA
GATGAAATTCCATTTGTAGGTAGTGAGACAAAATTGATGATCCATTAAGTAAACAATAAAAGTGTCCATTGAAACCGTGATTTTTTTTTT
TTTCCTGTCATACTTTGTTAGGAAGGGTGAGAATAGAATCTTGAGGAACGGATCAGATGTCTATATTGCTGAATGCAAGAAGTGGGGCAG
CAGCAGTGGAGAGATGGGACAATTAGATAAATGTCCATTCTTTATCAAGGGCCTACTTTATGGCAGACATTGTGCTAGTGCTTTTATTCT
AACTTTTATTTTTATCAGTTACACATGATCATAATTTAAAAAGTCAAGGCTTATAACAAAAAAGCCCCAGCCCATTCCTCCCATTCAAGA
TTCCCACTCCCCAGAGGTGACCACTTTCAACTCTTGAGTTTTTCAGGTATATACCTCCATGTTTCTAAGTAATATGCTTATATTGTTCAC
TTCTTTTTTTTTTATTTTTTAAAGAAATCTATTTCATACCATGGAGGAAGGCTCTGTTCCACATATATTTCCACTTCTTCATTCTCTCGG
TATAGTTTTGTCACAATTATAGATTAGATCAAAAGTCTACATAACTAATACAGCTGAGCTATGTAGTATGCTATGATTAAATTTACTTAT
GTAACTTTTATTGTCTTTGGCATTAACAGTGTTTCAAAAAATTTTCTGTGTATACCCATCAGTGATTCATTCCCAAATCTTCTAGAAGCA
TAAGTGTCTCAATATATTAAAACATATTGAATAATCCTTGTTAGAGTTATCCCTGCAGGAGTCCTTAGTGCTCCTTTATCCAATTTGTAC
TTGATGCCCTCTAGGCAGGGTGTACAGCTAGCTGTTGCTCTGGTATTTCCTATAACCTTCTTGGGGATTTCTTTTACCTCCTGTGTTAGA
CTCCTGTTTTCTGGATTCCCCCTTTTCCCTCTTTCTTGGTCTACTTTTTGTAGAACACAAGACTCTACTAGCTTCCTGAGAAAGGGTGCC
TGGGAGGCAAAATCTCTAAGACTTTGTAAGTCTGAAAATGTCTTTATTCGACCCTTATACTTGATTCCTAGTTTGGCTATATATAGAATT
TTAGCCTGAGTATCACTTTTTGAGACTCGAAGCCACTGTTTCATTGTCACTATTGAGAATCTAAATGGCCATTCGGATTCTTTCATCATC
TTTATAATTTTACCTTCCTATTTCTTTCCTGTCCTTTTAATGGAGTTTTGGGAGAGAGCAGAGGTAAACATGATTTGAAAAAGCCATGTC
TGACCAGAAATTCTGTGCTGGAAAGATATGTATTTCACCTTTAGGGACAAAGAAATAAACTTTTGGACAGGACCACAGAGCTAGTAAGTA
ACAGCAGGGATTCAAGTCCAGGTTTGTCTGGTTCCAGTGGCTGATGCTTTTCCAATGTGCCTCCGTCCCTGACATGATGCTTCTAGGCTA
TAGATGCTTCTAGACTCTATCCCTGACATGATGCTTCTAGACTATTTTGTTTAACCCTGGATAGAATAGCAAAAGAAAATTTTGGTGGTT
GCTCTAAACAAAACAGAAATTTGAAAGCTCAAGTTTTTTCTTCATTTGTATTTTAGTTAATACTGTACCCATATTTGTAGTTAATTTTAA
ATTGTACCATGTTTCTGCATACCTCTATGGGTACTCAGGAATTCTAGTCCAATTTTTGTGACTTTTTCCTACTGATTACCTTTCCTCCAA
CGTTTTAAAAATTATTTCAAATGGAACTGAAAGAAGCATAAACTCCCATAAACCCAGCACCTAGACTCTACAATTGCCAACATTATCTAT
CCAACAATCTCTGACTGTACCTTTTAAGTACTTTCTACTGGACTGTTTCCAGGATCACCCCTCATTTATTTGGGTTGTTAACCTAAAGAA
TGAATGGGGGAATCTCCAGTCATAAACAACTTGTCAATTAGGCAAATATTTGAGTTCCTTCTATGTGCTTAAAGACGTGATAGAGGGAAT
ATAAGAGCATTTATGTTCTGAAGGAATTTTTAACCTAACCAAAGAAGATAGTAGATAACTTGTGTGCATATAAGCTAGAACAGTATAAGG
GGCCGGGCATGGTGGCTTACGCCTGTAATCCCAGGACTTTGGGAGGCCAAGGCGGGCAGATCACCTGTCAGGAGTTTGGGACCAGCCTGG
CCAACATGGTGAAACCCCGTTTCTACCAAAAATACAAAAATTAGCCGGGCGTGGTGGCGTGTGCCACTGTAGTCCCAGCTATTCAGAAGG
CTGAGGCAGGAGAATCACTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCACGCTACTGCATTCCTGCTTGGGCGACAGAGTGA
GACTCTGCCTCAAAACAAAAACCCCACAAAACAGTATAAGGATGTGCTTTCTAATTTGGAATTATGAATTATTGGTAAAATATTGCAAAG
GTGTATGCTTTAAGTTGTAAATTCACCTTTAACCCTAGACTATATATGTGTGTTTATATGCAGAAAAAAATAATTCCCATGTCGTAAGTG
AACAATTTGGTTCTTTAGCTCAGTGTTTTCCTGTTTTCTTCATTTCCAAAATTTCCCTCTAGCACAGGGGTTTACACATGATCAAAAAGG
AGTATACAATGAAGACACCTTCCTCAGTCCCCTACCTACCAGTTTCCCTCCCCAGAAGCAACCTCTGGAAGACCAGTTTCTTTCAATCTA
AGGCTATTTAATATACATTAAGAGGCCGGGCGCAGTGGCTCACGCCTGTAATCCCAACAACACTTTGGGAGGCCCAGGCAGGCGGGTCAT
GAGGTCAGGAGATTGAGACCATCCTGGCTAACACGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGATGGTGGGC
GCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAAGCGGAGCTCGCAGTGAGCCGAGATCACGCCACT
GCACTCCAGCCTGGGCAACAGTGAGACTCTGCATAAAGAGCATACCCATGTGTGTACCTATCTATCTATCTATCTATCTATCTATCTATC

>75807_75807_1_RPL10-PGK1_RPL10_chrX_153628282_ENST00000369817_PGK1_chrX_77369512_ENST00000373316_length(amino acids)=481AA_BP=154
MTERPPVFDRTLWFLRAQTDRLYKPCAGGGAPLSLRCATEDPGVAMGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDE
FPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRDVLFLKDCVGPEVEKACANPAAGSV
ILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPER
PFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENA
KTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTE

--------------------------------------------------------------
>75807_75807_2_RPL10-PGK1_RPL10_chrX_153628282_ENST00000406022_PGK1_chrX_77369512_ENST00000373316_length(transcript)=4825nt_BP=377nt
CGGGAAAAACGGGTGCGGCCGCCTCCTGTGTCCTACAGGGGGCGCCAGACGCATTTCCACTCGGCTTGGAGTTACCGGTATTGTAAGAAC
AAGCCGTACCCAAAGTCTCGCTTCTGCCGAGGTGTCCCTGATGCCAAGATTCGCATTTTTGACCTGGGGCGGAAAAAGGCAAAAGTGGAT
GAGTTTCCGCTTTGTGGCCACATGGTGTCAGATGAATATGAGCAGCTGTCCTCTGAAGCCCTGGAGGCTGCCCGAATTTGTGCCAATAAG
TACATGGTAAAAAGTTGTGGCAAAGATGGCTTCCATATCCGGGTGCGGCTCCACCCCTTCCACGTCATCCGCATCAACAAGATGTTGTCC
TGTGCTGGGGCTGACAGGGATGTTCTGTTCTTGAAGGACTGTGTAGGCCCAGAAGTGGAGAAAGCCTGTGCCAACCCAGCTGCTGGGTCT
GTCATCCTGCTGGAGAACCTCCGCTTTCATGTGGAGGAAGAAGGGAAGGGAAAAGATGCTTCTGGGAACAAGGTTAAAGCCGAGCCAGCC
AAAATAGAAGCTTTCCGAGCTTCACTTTCCAAGCTAGGGGATGTCTATGTCAATGATGCTTTTGGCACTGCTCACAGAGCCCACAGCTCC
ATGGTAGGAGTCAATCTGCCACAGAAGGCTGGTGGGTTTTTGATGAAGAAGGAGCTGAACTACTTTGCAAAGGCCTTGGAGAGCCCAGAG
CGACCCTTCCTGGCCATCCTGGGCGGAGCTAAAGTTGCAGACAAGATCCAGCTCATCAATAATATGCTGGACAAAGTCAATGAGATGATT
ATTGGTGGTGGAATGGCTTTTACCTTCCTTAAGGTGCTCAACAACATGGAGATTGGCACTTCTCTGTTTGATGAAGAGGGAGCCAAGATT
GTCAAAGACCTAATGTCCAAAGCTGAGAAGAATGGTGTGAAGATTACCTTGCCTGTTGACTTTGTCACTGCTGACAAGTTTGATGAGAAT
GCCAAGACTGGCCAAGCCACTGTGGCTTCTGGCATACCTGCTGGCTGGATGGGCTTGGACTGTGGTCCTGAAAGCAGCAAGAAGTATGCT
GAGGCTGTCACTCGGGCTAAGCAGATTGTGTGGAATGGTCCTGTGGGGGTATTTGAATGGGAAGCTTTTGCCCGGGGAACCAAAGCTCTC
ATGGATGAGGTGGTGAAAGCCACTTCTAGGGGCTGCATCACCATCATAGGTGGTGGAGACACTGCCACTTGCTGTGCCAAATGGAACACG
GAGGATAAAGTCAGCCATGTGAGCACTGGGGGTGGTGCCAGTTTGGAGCTCCTGGAAGGTAAAGTCCTTCCTGGGGTGGATGCTCTCAGC
AATATTTAGTACTTTCCTGCCTTTTAGTTCCTGTGCACAGCCCCTAAGTCAACTTAGCATTTTCTGCATCTCCACTTGGCATTAGCTAAA
ACCTTCCATGTCAAGATTCAGCTAGTGGCCAAGAGATGCAGTGCCAGGAACCCTTAAACAGTTGCACAGCATCTCAGCTCATCTTCACTG
CACCCTGGATTTGCATACATTCTTCAAGATCCCATTTGAATTTTTTAGTGACTAAACCATTGTGCATTCTAGAGTGCATATATTTATATT
TTGCCTGTTAAAAAGAAAGTGAGCAGTGTTAGCTTAGTTCTCTTTTGATGTAGGTTATTATGATTAGCTTTGTCACTGTTTCACTACTCA
GCATGGAAACAAGATGAAATTCCATTTGTAGGTAGTGAGACAAAATTGATGATCCATTAAGTAAACAATAAAAGTGTCCATTGAAACCGT
GATTTTTTTTTTTTTCCTGTCATACTTTGTTAGGAAGGGTGAGAATAGAATCTTGAGGAACGGATCAGATGTCTATATTGCTGAATGCAA
GAAGTGGGGCAGCAGCAGTGGAGAGATGGGACAATTAGATAAATGTCCATTCTTTATCAAGGGCCTACTTTATGGCAGACATTGTGCTAG
TGCTTTTATTCTAACTTTTATTTTTATCAGTTACACATGATCATAATTTAAAAAGTCAAGGCTTATAACAAAAAAGCCCCAGCCCATTCC
TCCCATTCAAGATTCCCACTCCCCAGAGGTGACCACTTTCAACTCTTGAGTTTTTCAGGTATATACCTCCATGTTTCTAAGTAATATGCT
TATATTGTTCACTTCTTTTTTTTTTATTTTTTAAAGAAATCTATTTCATACCATGGAGGAAGGCTCTGTTCCACATATATTTCCACTTCT
TCATTCTCTCGGTATAGTTTTGTCACAATTATAGATTAGATCAAAAGTCTACATAACTAATACAGCTGAGCTATGTAGTATGCTATGATT
AAATTTACTTATGTAACTTTTATTGTCTTTGGCATTAACAGTGTTTCAAAAAATTTTCTGTGTATACCCATCAGTGATTCATTCCCAAAT
CTTCTAGAAGCATAAGTGTCTCAATATATTAAAACATATTGAATAATCCTTGTTAGAGTTATCCCTGCAGGAGTCCTTAGTGCTCCTTTA
TCCAATTTGTACTTGATGCCCTCTAGGCAGGGTGTACAGCTAGCTGTTGCTCTGGTATTTCCTATAACCTTCTTGGGGATTTCTTTTACC
TCCTGTGTTAGACTCCTGTTTTCTGGATTCCCCCTTTTCCCTCTTTCTTGGTCTACTTTTTGTAGAACACAAGACTCTACTAGCTTCCTG
AGAAAGGGTGCCTGGGAGGCAAAATCTCTAAGACTTTGTAAGTCTGAAAATGTCTTTATTCGACCCTTATACTTGATTCCTAGTTTGGCT
ATATATAGAATTTTAGCCTGAGTATCACTTTTTGAGACTCGAAGCCACTGTTTCATTGTCACTATTGAGAATCTAAATGGCCATTCGGAT
TCTTTCATCATCTTTATAATTTTACCTTCCTATTTCTTTCCTGTCCTTTTAATGGAGTTTTGGGAGAGAGCAGAGGTAAACATGATTTGA
AAAAGCCATGTCTGACCAGAAATTCTGTGCTGGAAAGATATGTATTTCACCTTTAGGGACAAAGAAATAAACTTTTGGACAGGACCACAG
AGCTAGTAAGTAACAGCAGGGATTCAAGTCCAGGTTTGTCTGGTTCCAGTGGCTGATGCTTTTCCAATGTGCCTCCGTCCCTGACATGAT
GCTTCTAGGCTATAGATGCTTCTAGACTCTATCCCTGACATGATGCTTCTAGACTATTTTGTTTAACCCTGGATAGAATAGCAAAAGAAA
ATTTTGGTGGTTGCTCTAAACAAAACAGAAATTTGAAAGCTCAAGTTTTTTCTTCATTTGTATTTTAGTTAATACTGTACCCATATTTGT
AGTTAATTTTAAATTGTACCATGTTTCTGCATACCTCTATGGGTACTCAGGAATTCTAGTCCAATTTTTGTGACTTTTTCCTACTGATTA
CCTTTCCTCCAACGTTTTAAAAATTATTTCAAATGGAACTGAAAGAAGCATAAACTCCCATAAACCCAGCACCTAGACTCTACAATTGCC
AACATTATCTATCCAACAATCTCTGACTGTACCTTTTAAGTACTTTCTACTGGACTGTTTCCAGGATCACCCCTCATTTATTTGGGTTGT
TAACCTAAAGAATGAATGGGGGAATCTCCAGTCATAAACAACTTGTCAATTAGGCAAATATTTGAGTTCCTTCTATGTGCTTAAAGACGT
GATAGAGGGAATATAAGAGCATTTATGTTCTGAAGGAATTTTTAACCTAACCAAAGAAGATAGTAGATAACTTGTGTGCATATAAGCTAG
AACAGTATAAGGGGCCGGGCATGGTGGCTTACGCCTGTAATCCCAGGACTTTGGGAGGCCAAGGCGGGCAGATCACCTGTCAGGAGTTTG
GGACCAGCCTGGCCAACATGGTGAAACCCCGTTTCTACCAAAAATACAAAAATTAGCCGGGCGTGGTGGCGTGTGCCACTGTAGTCCCAG
CTATTCAGAAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCACGCTACTGCATTCCTGCTTGG
GCGACAGAGTGAGACTCTGCCTCAAAACAAAAACCCCACAAAACAGTATAAGGATGTGCTTTCTAATTTGGAATTATGAATTATTGGTAA
AATATTGCAAAGGTGTATGCTTTAAGTTGTAAATTCACCTTTAACCCTAGACTATATATGTGTGTTTATATGCAGAAAAAAATAATTCCC
ATGTCGTAAGTGAACAATTTGGTTCTTTAGCTCAGTGTTTTCCTGTTTTCTTCATTTCCAAAATTTCCCTCTAGCACAGGGGTTTACACA
TGATCAAAAAGGAGTATACAATGAAGACACCTTCCTCAGTCCCCTACCTACCAGTTTCCCTCCCCAGAAGCAACCTCTGGAAGACCAGTT
TCTTTCAATCTAAGGCTATTTAATATACATTAAGAGGCCGGGCGCAGTGGCTCACGCCTGTAATCCCAACAACACTTTGGGAGGCCCAGG
CAGGCGGGTCATGAGGTCAGGAGATTGAGACCATCCTGGCTAACACGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCTGGGC
GTGATGGTGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAAGCGGAGCTCGCAGTGAGCCGA
GATCACGCCACTGCACTCCAGCCTGGGCAACAGTGAGACTCTGCATAAAGAGCATACCCATGTGTGTACCTATCTATCTATCTATCTATC

>75807_75807_2_RPL10-PGK1_RPL10_chrX_153628282_ENST00000406022_PGK1_chrX_77369512_ENST00000373316_length(amino acids)=401AA_BP=74
MGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRDVLFLKDCVGPEVEK
ACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNY
FAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDF
VTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDT

--------------------------------------------------------------
>75807_75807_3_RPL10-PGK1_RPL10_chrX_153628282_ENST00000424325_PGK1_chrX_77369512_ENST00000373316_length(transcript)=4965nt_BP=517nt
GGGCTACGCCCGGGCGCAAGCGCCAAGAGCGGCTGCGTCTATGGTCATGACGTCTGACAGAGCGTCCACCCGTCTTCGACAGGACTCTAT
GGTTCTTACGCGCGCAGACAGACCGCCTATATAAGCCATGCGCAGGCGGAGGAGCGCCTCTTTCCCTTCGGTGTGCCACTGAAGATCCTG
GTGTCGCCATGGGCCGCCGCCCCGCCCGTTGTTACCGGTATTGTAAGAACAAGCCGTACCCAAAGTCTCGCTTCTGCCGAGGTGTCCCTG
ATGCCAAGATTCGCATTTTTGACCTGGGGCGGAAAAAGGCAAAAGTGGATGAGTTTCCGCTTTGTGGCCACATGGTGTCAGATGAATATG
AGCAGCTGTCCTCTGAAGCCCTGGAGGCTGCCCGAATTTGTGCCAATAAGTACATGGTAAAAAGTTGTGGCAAAGATGGCTTCCATATCC
GGGTGCGGCTCCACCCCTTCCACGTCATCCGCATCAACAAGATGTTGTCCTGTGCTGGGGCTGACAGGGATGTTCTGTTCTTGAAGGACT
GTGTAGGCCCAGAAGTGGAGAAAGCCTGTGCCAACCCAGCTGCTGGGTCTGTCATCCTGCTGGAGAACCTCCGCTTTCATGTGGAGGAAG
AAGGGAAGGGAAAAGATGCTTCTGGGAACAAGGTTAAAGCCGAGCCAGCCAAAATAGAAGCTTTCCGAGCTTCACTTTCCAAGCTAGGGG
ATGTCTATGTCAATGATGCTTTTGGCACTGCTCACAGAGCCCACAGCTCCATGGTAGGAGTCAATCTGCCACAGAAGGCTGGTGGGTTTT
TGATGAAGAAGGAGCTGAACTACTTTGCAAAGGCCTTGGAGAGCCCAGAGCGACCCTTCCTGGCCATCCTGGGCGGAGCTAAAGTTGCAG
ACAAGATCCAGCTCATCAATAATATGCTGGACAAAGTCAATGAGATGATTATTGGTGGTGGAATGGCTTTTACCTTCCTTAAGGTGCTCA
ACAACATGGAGATTGGCACTTCTCTGTTTGATGAAGAGGGAGCCAAGATTGTCAAAGACCTAATGTCCAAAGCTGAGAAGAATGGTGTGA
AGATTACCTTGCCTGTTGACTTTGTCACTGCTGACAAGTTTGATGAGAATGCCAAGACTGGCCAAGCCACTGTGGCTTCTGGCATACCTG
CTGGCTGGATGGGCTTGGACTGTGGTCCTGAAAGCAGCAAGAAGTATGCTGAGGCTGTCACTCGGGCTAAGCAGATTGTGTGGAATGGTC
CTGTGGGGGTATTTGAATGGGAAGCTTTTGCCCGGGGAACCAAAGCTCTCATGGATGAGGTGGTGAAAGCCACTTCTAGGGGCTGCATCA
CCATCATAGGTGGTGGAGACACTGCCACTTGCTGTGCCAAATGGAACACGGAGGATAAAGTCAGCCATGTGAGCACTGGGGGTGGTGCCA
GTTTGGAGCTCCTGGAAGGTAAAGTCCTTCCTGGGGTGGATGCTCTCAGCAATATTTAGTACTTTCCTGCCTTTTAGTTCCTGTGCACAG
CCCCTAAGTCAACTTAGCATTTTCTGCATCTCCACTTGGCATTAGCTAAAACCTTCCATGTCAAGATTCAGCTAGTGGCCAAGAGATGCA
GTGCCAGGAACCCTTAAACAGTTGCACAGCATCTCAGCTCATCTTCACTGCACCCTGGATTTGCATACATTCTTCAAGATCCCATTTGAA
TTTTTTAGTGACTAAACCATTGTGCATTCTAGAGTGCATATATTTATATTTTGCCTGTTAAAAAGAAAGTGAGCAGTGTTAGCTTAGTTC
TCTTTTGATGTAGGTTATTATGATTAGCTTTGTCACTGTTTCACTACTCAGCATGGAAACAAGATGAAATTCCATTTGTAGGTAGTGAGA
CAAAATTGATGATCCATTAAGTAAACAATAAAAGTGTCCATTGAAACCGTGATTTTTTTTTTTTTCCTGTCATACTTTGTTAGGAAGGGT
GAGAATAGAATCTTGAGGAACGGATCAGATGTCTATATTGCTGAATGCAAGAAGTGGGGCAGCAGCAGTGGAGAGATGGGACAATTAGAT
AAATGTCCATTCTTTATCAAGGGCCTACTTTATGGCAGACATTGTGCTAGTGCTTTTATTCTAACTTTTATTTTTATCAGTTACACATGA
TCATAATTTAAAAAGTCAAGGCTTATAACAAAAAAGCCCCAGCCCATTCCTCCCATTCAAGATTCCCACTCCCCAGAGGTGACCACTTTC
AACTCTTGAGTTTTTCAGGTATATACCTCCATGTTTCTAAGTAATATGCTTATATTGTTCACTTCTTTTTTTTTTATTTTTTAAAGAAAT
CTATTTCATACCATGGAGGAAGGCTCTGTTCCACATATATTTCCACTTCTTCATTCTCTCGGTATAGTTTTGTCACAATTATAGATTAGA
TCAAAAGTCTACATAACTAATACAGCTGAGCTATGTAGTATGCTATGATTAAATTTACTTATGTAACTTTTATTGTCTTTGGCATTAACA
GTGTTTCAAAAAATTTTCTGTGTATACCCATCAGTGATTCATTCCCAAATCTTCTAGAAGCATAAGTGTCTCAATATATTAAAACATATT
GAATAATCCTTGTTAGAGTTATCCCTGCAGGAGTCCTTAGTGCTCCTTTATCCAATTTGTACTTGATGCCCTCTAGGCAGGGTGTACAGC
TAGCTGTTGCTCTGGTATTTCCTATAACCTTCTTGGGGATTTCTTTTACCTCCTGTGTTAGACTCCTGTTTTCTGGATTCCCCCTTTTCC
CTCTTTCTTGGTCTACTTTTTGTAGAACACAAGACTCTACTAGCTTCCTGAGAAAGGGTGCCTGGGAGGCAAAATCTCTAAGACTTTGTA
AGTCTGAAAATGTCTTTATTCGACCCTTATACTTGATTCCTAGTTTGGCTATATATAGAATTTTAGCCTGAGTATCACTTTTTGAGACTC
GAAGCCACTGTTTCATTGTCACTATTGAGAATCTAAATGGCCATTCGGATTCTTTCATCATCTTTATAATTTTACCTTCCTATTTCTTTC
CTGTCCTTTTAATGGAGTTTTGGGAGAGAGCAGAGGTAAACATGATTTGAAAAAGCCATGTCTGACCAGAAATTCTGTGCTGGAAAGATA
TGTATTTCACCTTTAGGGACAAAGAAATAAACTTTTGGACAGGACCACAGAGCTAGTAAGTAACAGCAGGGATTCAAGTCCAGGTTTGTC
TGGTTCCAGTGGCTGATGCTTTTCCAATGTGCCTCCGTCCCTGACATGATGCTTCTAGGCTATAGATGCTTCTAGACTCTATCCCTGACA
TGATGCTTCTAGACTATTTTGTTTAACCCTGGATAGAATAGCAAAAGAAAATTTTGGTGGTTGCTCTAAACAAAACAGAAATTTGAAAGC
TCAAGTTTTTTCTTCATTTGTATTTTAGTTAATACTGTACCCATATTTGTAGTTAATTTTAAATTGTACCATGTTTCTGCATACCTCTAT
GGGTACTCAGGAATTCTAGTCCAATTTTTGTGACTTTTTCCTACTGATTACCTTTCCTCCAACGTTTTAAAAATTATTTCAAATGGAACT
GAAAGAAGCATAAACTCCCATAAACCCAGCACCTAGACTCTACAATTGCCAACATTATCTATCCAACAATCTCTGACTGTACCTTTTAAG
TACTTTCTACTGGACTGTTTCCAGGATCACCCCTCATTTATTTGGGTTGTTAACCTAAAGAATGAATGGGGGAATCTCCAGTCATAAACA
ACTTGTCAATTAGGCAAATATTTGAGTTCCTTCTATGTGCTTAAAGACGTGATAGAGGGAATATAAGAGCATTTATGTTCTGAAGGAATT
TTTAACCTAACCAAAGAAGATAGTAGATAACTTGTGTGCATATAAGCTAGAACAGTATAAGGGGCCGGGCATGGTGGCTTACGCCTGTAA
TCCCAGGACTTTGGGAGGCCAAGGCGGGCAGATCACCTGTCAGGAGTTTGGGACCAGCCTGGCCAACATGGTGAAACCCCGTTTCTACCA
AAAATACAAAAATTAGCCGGGCGTGGTGGCGTGTGCCACTGTAGTCCCAGCTATTCAGAAGGCTGAGGCAGGAGAATCACTTGAACCCGG
GAGGTGGAGGTTGCAGTGAGCTGAGATCACGCTACTGCATTCCTGCTTGGGCGACAGAGTGAGACTCTGCCTCAAAACAAAAACCCCACA
AAACAGTATAAGGATGTGCTTTCTAATTTGGAATTATGAATTATTGGTAAAATATTGCAAAGGTGTATGCTTTAAGTTGTAAATTCACCT
TTAACCCTAGACTATATATGTGTGTTTATATGCAGAAAAAAATAATTCCCATGTCGTAAGTGAACAATTTGGTTCTTTAGCTCAGTGTTT
TCCTGTTTTCTTCATTTCCAAAATTTCCCTCTAGCACAGGGGTTTACACATGATCAAAAAGGAGTATACAATGAAGACACCTTCCTCAGT
CCCCTACCTACCAGTTTCCCTCCCCAGAAGCAACCTCTGGAAGACCAGTTTCTTTCAATCTAAGGCTATTTAATATACATTAAGAGGCCG
GGCGCAGTGGCTCACGCCTGTAATCCCAACAACACTTTGGGAGGCCCAGGCAGGCGGGTCATGAGGTCAGGAGATTGAGACCATCCTGGC
TAACACGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGATGGTGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCT
GAGGCAGGAGAATGGCGTGAACCTGGGAAGCGGAGCTCGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGTGAGACT
CTGCATAAAGAGCATACCCATGTGTGTACCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTGTATATAGATATATTAAAA

>75807_75807_3_RPL10-PGK1_RPL10_chrX_153628282_ENST00000424325_PGK1_chrX_77369512_ENST00000373316_length(amino acids)=481AA_BP=154
MTERPPVFDRTLWFLRAQTDRLYKPCAGGGAPLSLRCATEDPGVAMGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDE
FPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRDVLFLKDCVGPEVEKACANPAAGSV
ILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPER
PFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENA
KTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTE

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for RPL10-PGK1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for RPL10-PGK1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for RPL10-PGK1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source