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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:RPL23-BRD2 (FusionGDB2 ID:76210)

Fusion Gene Summary for RPL23-BRD2

Fusion gene summary

Fusion gene information	Fusion gene name: RPL23-BRD2
	Fusion gene ID: 76210
		Hgene	Tgene
	Gene symbol	RPL23	BRD2
	Gene ID	9349	6046
	Gene name	ribosomal protein L23	bromodomain containing 2
	Synonyms	L23\|rpL17	BRD2-IT1\|D6S113E\|FSH\|FSRG1\|NAT\|O27.1.1\|RING3\|RNF3
	Cytomap	17q12	6p21.32
	Type of gene	protein-coding	protein-coding
	Description	60S ribosomal protein L2360S ribosomal protein L17large ribosomal subunit protein uL14ribosomal protein L17	bromodomain-containing protein 2BRD2 intronic transcript 1female sterile homeotic-related gene 1really interesting new gene 3 protein
	Modification date	20200313	20200313
	UniProtAcc	.	P25440
	Ensembl transtripts involved in fusion gene	ENST00000245857, ENST00000394332, ENST00000394333, ENST00000479035, ENST00000577407,	ENST00000580234, ENST00000374825, ENST00000374831, ENST00000395289, ENST00000443797, ENST00000496118, ENST00000383108, ENST00000395287, ENST00000399527, ENST00000399528, ENST00000399529, ENST00000414731, ENST00000425201, ENST00000436979, ENST00000438194, ENST00000442219, ENST00000442863, ENST00000448067, ENST00000449085, ENST00000449118, ENST00000450320, ENST00000466208, ENST00000466744, ENST00000479973, ENST00000482105, ENST00000488549, ENST00000498329, ENST00000546777, ENST00000547286, ENST00000547895, ENST00000548837, ENST00000549126, ENST00000549236, ENST00000549843, ENST00000550142, ENST00000550598, ENST00000552513, ENST00000552587, ENST00000553146,
Fusion gene scores	* DoF score	30 X 21 X 6=3780	10 X 15 X 3=450
	# samples	33	16
	** MAII score	log2(33/3780*10)=-3.51784830486262 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(16/450*10)=-1.49185309632967 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: RPL23 [Title/Abstract] AND BRD2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	RPL23(37008857)-BRD2(32939372), # samples:2 RPL23(37008856)-BRD2(32939371), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	RPL23	GO:0032986	protein-DNA complex disassembly	19160485
Hgene	RPL23	GO:1904667	negative regulation of ubiquitin protein ligase activity	15314173
Hgene	RPL23	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	15314173
Tgene	BRD2	GO:0006357	regulation of transcription by RNA polymerase II	18406326

Fusion gene breakpoints across RPL23 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across BRD2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	PRAD	TCGA-CH-5751-01A	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
ChimerDB4	PRAD	TCGA-CH-5751	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
ChimerDB4	PRAD	TCGA-CH-5751	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+

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Fusion Gene ORF analysis for RPL23-BRD2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000245857	ENST00000580234	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-3UTR	ENST00000245857	ENST00000580234	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-3UTR	ENST00000394332	ENST00000580234	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-3UTR	ENST00000394332	ENST00000580234	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-3UTR	ENST00000394333	ENST00000580234	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-3UTR	ENST00000394333	ENST00000580234	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-3UTR	ENST00000479035	ENST00000580234	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-3UTR	ENST00000479035	ENST00000580234	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-3UTR	ENST00000577407	ENST00000580234	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-3UTR	ENST00000577407	ENST00000580234	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000245857	ENST00000374825	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000245857	ENST00000374825	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000245857	ENST00000374831	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000245857	ENST00000374831	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000245857	ENST00000395289	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000245857	ENST00000395289	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000245857	ENST00000443797	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000245857	ENST00000443797	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000245857	ENST00000496118	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000245857	ENST00000496118	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000394332	ENST00000374825	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000394332	ENST00000374825	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000394332	ENST00000374831	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000394332	ENST00000374831	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000394332	ENST00000395289	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000394332	ENST00000395289	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000394332	ENST00000443797	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000394332	ENST00000443797	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000394332	ENST00000496118	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000394332	ENST00000496118	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000394333	ENST00000374825	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000394333	ENST00000374825	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000394333	ENST00000374831	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000394333	ENST00000374831	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000394333	ENST00000395289	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000394333	ENST00000395289	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000394333	ENST00000443797	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000394333	ENST00000443797	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000394333	ENST00000496118	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000394333	ENST00000496118	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000479035	ENST00000374825	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000479035	ENST00000374825	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000479035	ENST00000374831	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000479035	ENST00000374831	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000479035	ENST00000395289	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000479035	ENST00000395289	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000479035	ENST00000443797	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000479035	ENST00000443797	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000479035	ENST00000496118	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000479035	ENST00000496118	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000577407	ENST00000374825	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000577407	ENST00000374825	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000577407	ENST00000374831	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000577407	ENST00000374831	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000577407	ENST00000395289	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000577407	ENST00000395289	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000577407	ENST00000443797	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000577407	ENST00000443797	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-5UTR	ENST00000577407	ENST00000496118	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-5UTR	ENST00000577407	ENST00000496118	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000383108	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000383108	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000395287	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000395287	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000399527	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000399527	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000399528	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000399528	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000399529	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000399529	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000414731	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000414731	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000425201	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000425201	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000436979	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000436979	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000438194	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000438194	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000442219	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000442219	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000442863	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000442863	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000448067	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000448067	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000449085	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000449085	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000449118	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000449118	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000450320	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000450320	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000466208	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000466208	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000466744	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000466744	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000479973	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000479973	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000482105	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000482105	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000488549	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000488549	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000498329	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000498329	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000546777	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000546777	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000547286	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000547286	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000547895	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000547895	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000548837	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000548837	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000549126	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000549126	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000549236	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000549236	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000549843	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000549843	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000550142	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000550142	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000550598	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000550598	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000552513	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000552513	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000552587	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000552587	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000245857	ENST00000553146	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000245857	ENST00000553146	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000383108	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000383108	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000395287	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000395287	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000399527	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000399527	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000399528	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000399528	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000399529	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000399529	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000414731	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000414731	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000425201	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000425201	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000436979	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000436979	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000438194	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000438194	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000442219	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000442219	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000442863	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000442863	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000448067	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000448067	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000449085	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000449085	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000449118	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000449118	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000450320	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000450320	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000466208	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000466208	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000466744	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000466744	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000479973	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000479973	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000482105	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000482105	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000488549	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000488549	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000498329	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000498329	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000546777	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000546777	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000547286	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000547286	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000547895	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000547895	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000548837	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000548837	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000549126	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000549126	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000549236	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000549236	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000549843	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000549843	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000550142	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000550142	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000550598	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000550598	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000552513	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000552513	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000552587	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000552587	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394332	ENST00000553146	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394332	ENST00000553146	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000383108	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000383108	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000395287	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000395287	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000399527	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000399527	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000399528	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000399528	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000399529	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000399529	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000414731	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000414731	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000425201	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000425201	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000436979	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000436979	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000438194	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000438194	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000442219	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000442219	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000442863	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000442863	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000448067	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000448067	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000449085	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000449085	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000449118	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000449118	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000450320	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000450320	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000466208	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000466208	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000466744	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000466744	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000479973	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000479973	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000482105	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000482105	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000488549	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000488549	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000498329	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000498329	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000546777	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000546777	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000547286	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000547286	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000547895	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000547895	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000548837	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000548837	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000549126	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000549126	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000549236	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000549236	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000549843	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000549843	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000550142	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000550142	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000550598	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000550598	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000552513	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000552513	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000552587	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000552587	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000394333	ENST00000553146	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000394333	ENST00000553146	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000383108	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000383108	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000395287	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000395287	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000399527	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000399527	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000399528	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000399528	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000399529	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000399529	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000414731	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000414731	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000425201	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000425201	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000436979	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000436979	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000438194	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000438194	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000442219	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000442219	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000442863	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000442863	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000448067	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000448067	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000449085	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000449085	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000449118	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000449118	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000450320	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000450320	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000466208	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000466208	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000466744	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000466744	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000479973	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000479973	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000482105	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000482105	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000488549	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000488549	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000498329	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000498329	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000546777	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000546777	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000547286	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000547286	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000547895	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000547895	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000548837	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000548837	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000549126	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000549126	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000549236	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000549236	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000549843	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000549843	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000550142	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000550142	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000550598	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000550598	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000552513	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000552513	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000552587	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000552587	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000479035	ENST00000553146	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000479035	ENST00000553146	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000383108	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000383108	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000395287	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000395287	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000399527	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000399527	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000399528	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000399528	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000399529	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000399529	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000414731	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000414731	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000425201	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000425201	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000436979	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000436979	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000438194	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000438194	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000442219	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000442219	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000442863	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000442863	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000448067	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000448067	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000449085	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000449085	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000449118	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000449118	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000450320	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000450320	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000466208	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000466208	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000466744	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000466744	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000479973	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000479973	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000482105	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000482105	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000488549	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000488549	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000498329	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000498329	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000546777	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000546777	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000547286	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000547286	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000547895	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000547895	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000548837	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000548837	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000549126	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000549126	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000549236	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000549236	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000549843	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000549843	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000550142	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000550142	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000550598	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000550598	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000552513	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000552513	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000552587	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000552587	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+
5CDS-intron	ENST00000577407	ENST00000553146	RPL23	chr17	37008857	-	BRD2	chr6	32939372	+
5CDS-intron	ENST00000577407	ENST00000553146	RPL23	chr17	37008856	-	BRD2	chr6	32939371	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for RPL23-BRD2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
RPL23	chr17	37008856	-	BRD2	chr6	32939371	+	0.001180755	0.9988192
RPL23	chr17	37008856	-	BRD2	chr6	32939371	+	0.001180755	0.9988192
RPL23	chr17	37008856	-	BRD2	chr6	32939371	+	0.001180755	0.9988192
RPL23	chr17	37008856	-	BRD2	chr6	32939371	+	0.001180755	0.9988192

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RPL23-BRD2

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:37008857/:32939372)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	BRD2 P25440
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. {ECO:0000250, ECO:0000269\|PubMed:18406326}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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Fusion Gene Sequence for RPL23-BRD2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for RPL23-BRD2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for RPL23-BRD2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for RPL23-BRD2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source