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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RPL28-SOD1 (FusionGDB2 ID:76385)

Fusion Gene Summary for RPL28-SOD1

check button Fusion gene summary
Fusion gene informationFusion gene name: RPL28-SOD1
Fusion gene ID: 76385
HgeneTgene
Gene symbol

RPL28

SOD1

Gene ID

6158

6647

Gene nameribosomal protein L28superoxide dismutase 1
SynonymsL28ALS|ALS1|HEL-S-44|IPOA|SOD|STAHP|hSod1|homodimer
Cytomap

19q13.42

21q22.11

Type of geneprotein-codingprotein-coding
Description60S ribosomal protein L28large ribosomal subunit protein eL28superoxide dismutase [Cu-Zn]Cu/Zn superoxide dismutaseSOD, solubleepididymis secretory protein Li 44indophenoloxidase Asuperoxide dismutase 1, solublesuperoxide dismutase, cystolic
Modification date2020031320200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000558131, ENST00000344063, 
ENST00000458349, ENST00000558815, 
ENST00000559463, ENST00000560055, 
ENST00000560583, ENST00000428193, 
ENST00000431533, ENST00000558752, 
ENST00000270142, ENST00000389995, 
ENST00000470944, 
Fusion gene scores* DoF score22 X 17 X 5=18706 X 6 X 2=72
# samples 246
** MAII scorelog2(24/1870*10)=-2.96193195916648
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/72*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RPL28 [Title/Abstract] AND SOD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRPL28(55899416)-SOD1(33036103), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSOD1

GO:0000303

response to superoxide

16790527

TgeneSOD1

GO:0001819

positive regulation of cytokine production

15544046

TgeneSOD1

GO:0006801

superoxide metabolic process

12551919

TgeneSOD1

GO:0010033

response to organic substance

12921788

TgeneSOD1

GO:0032930

positive regulation of superoxide anion generation

18219391

TgeneSOD1

GO:0043085

positive regulation of catalytic activity

17324120

TgeneSOD1

GO:0043087

regulation of GTPase activity

18219391

TgeneSOD1

GO:0045541

negative regulation of cholesterol biosynthetic process

15473258

TgeneSOD1

GO:0045859

regulation of protein kinase activity

16254550

TgeneSOD1

GO:0050665

hydrogen peroxide biosynthetic process

15544046

TgeneSOD1

GO:0060047

heart contraction

9539776

TgeneSOD1

GO:0072593

reactive oxygen species metabolic process

24140062


check buttonFusion gene breakpoints across RPL28 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SOD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4PD-01ARPL28chr19

55899416

+SOD1chr21

33036103

+


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Fusion Gene ORF analysis for RPL28-SOD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000558131ENST00000270142RPL28chr19

55899416

+SOD1chr21

33036103

+
3UTR-3CDSENST00000558131ENST00000389995RPL28chr19

55899416

+SOD1chr21

33036103

+
3UTR-3UTRENST00000558131ENST00000470944RPL28chr19

55899416

+SOD1chr21

33036103

+
5CDS-3UTRENST00000344063ENST00000470944RPL28chr19

55899416

+SOD1chr21

33036103

+
5CDS-3UTRENST00000458349ENST00000470944RPL28chr19

55899416

+SOD1chr21

33036103

+
5CDS-3UTRENST00000558815ENST00000470944RPL28chr19

55899416

+SOD1chr21

33036103

+
5CDS-3UTRENST00000559463ENST00000470944RPL28chr19

55899416

+SOD1chr21

33036103

+
5CDS-3UTRENST00000560055ENST00000470944RPL28chr19

55899416

+SOD1chr21

33036103

+
5CDS-3UTRENST00000560583ENST00000470944RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000344063ENST00000270142RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000344063ENST00000389995RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000458349ENST00000270142RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000458349ENST00000389995RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000558815ENST00000270142RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000558815ENST00000389995RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000559463ENST00000270142RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000559463ENST00000389995RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000560055ENST00000270142RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000560055ENST00000389995RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000560583ENST00000270142RPL28chr19

55899416

+SOD1chr21

33036103

+
In-frameENST00000560583ENST00000389995RPL28chr19

55899416

+SOD1chr21

33036103

+
intron-3CDSENST00000428193ENST00000270142RPL28chr19

55899416

+SOD1chr21

33036103

+
intron-3CDSENST00000428193ENST00000389995RPL28chr19

55899416

+SOD1chr21

33036103

+
intron-3CDSENST00000431533ENST00000270142RPL28chr19

55899416

+SOD1chr21

33036103

+
intron-3CDSENST00000431533ENST00000389995RPL28chr19

55899416

+SOD1chr21

33036103

+
intron-3CDSENST00000558752ENST00000270142RPL28chr19

55899416

+SOD1chr21

33036103

+
intron-3CDSENST00000558752ENST00000389995RPL28chr19

55899416

+SOD1chr21

33036103

+
intron-3UTRENST00000428193ENST00000470944RPL28chr19

55899416

+SOD1chr21

33036103

+
intron-3UTRENST00000431533ENST00000470944RPL28chr19

55899416

+SOD1chr21

33036103

+
intron-3UTRENST00000558752ENST00000470944RPL28chr19

55899416

+SOD1chr21

33036103

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000344063RPL28chr1955899416+ENST00000270142SOD1chr2133036103+16999534461345299
ENST00000344063RPL28chr1955899416+ENST00000389995SOD1chr2133036103+16999534461345299
ENST00000558815RPL28chr1955899416+ENST00000270142SOD1chr2133036103+111236642758238
ENST00000558815RPL28chr1955899416+ENST00000389995SOD1chr2133036103+111236642758238
ENST00000560583RPL28chr1955899416+ENST00000270142SOD1chr2133036103+183110851159662165
ENST00000560583RPL28chr1955899416+ENST00000389995SOD1chr2133036103+183110851159662165
ENST00000560055RPL28chr1955899416+ENST00000270142SOD1chr2133036103+110836238754238
ENST00000560055RPL28chr1955899416+ENST00000389995SOD1chr2133036103+110836238754238
ENST00000559463RPL28chr1955899416+ENST00000270142SOD1chr2133036103+14677213971113238
ENST00000559463RPL28chr1955899416+ENST00000389995SOD1chr2133036103+14677213971113238
ENST00000458349RPL28chr1955899416+ENST00000270142SOD1chr2133036103+10703240716238
ENST00000458349RPL28chr1955899416+ENST00000389995SOD1chr2133036103+10703240716238

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000344063ENST00000270142RPL28chr1955899416+SOD1chr2133036103+0.0003998430.99960023
ENST00000344063ENST00000389995RPL28chr1955899416+SOD1chr2133036103+0.0003998430.99960023
ENST00000558815ENST00000270142RPL28chr1955899416+SOD1chr2133036103+0.0001898130.99981016
ENST00000558815ENST00000389995RPL28chr1955899416+SOD1chr2133036103+0.0001898130.99981016
ENST00000560583ENST00000270142RPL28chr1955899416+SOD1chr2133036103+0.091293250.9087067
ENST00000560583ENST00000389995RPL28chr1955899416+SOD1chr2133036103+0.091293250.9087067
ENST00000560055ENST00000270142RPL28chr1955899416+SOD1chr2133036103+0.0002159110.99978405
ENST00000560055ENST00000389995RPL28chr1955899416+SOD1chr2133036103+0.0002159110.99978405
ENST00000559463ENST00000270142RPL28chr1955899416+SOD1chr2133036103+0.0002123230.99978775
ENST00000559463ENST00000389995RPL28chr1955899416+SOD1chr2133036103+0.0002123230.99978775
ENST00000458349ENST00000270142RPL28chr1955899416+SOD1chr2133036103+0.0001913940.9998086
ENST00000458349ENST00000389995RPL28chr1955899416+SOD1chr2133036103+0.0001913940.9998086

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Fusion Genomic Features for RPL28-SOD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RPL28chr1955899416+SOD1chr2133036102+1.40E-070.9999999
RPL28chr1955899416+SOD1chr2133036102+1.40E-070.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for RPL28-SOD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:55899416/chr21:33036103)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for RPL28-SOD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>76385_76385_1_RPL28-SOD1_RPL28_chr19_55899416_ENST00000344063_SOD1_chr21_33036103_ENST00000270142_length(transcript)=1699nt_BP=953nt
GGGAGGGCGAACTGCAAGAGGGCTGCCAGGATTAGCCGAGGGATTCCGAATGAAGACGGAGTATTTCCGAACATACACACCTCTCCCAAG
AGCGTTTCCGGAGGGTTCCGAAAATACCCGAGCGGGCCTCGGCGCCCTCATTGGCCATCACCGCGAGGGCTTACGAAGACCGGAAATATC
CAAAGGTGCCGGGGCTAGGCTTATATAGTTCACGCATTCACCAGTTCATTCATAAAACAAATGTTTGTTGAGCGCCCATCATATGCCAAT
CACAGTGACAAGTGCTGGGTGAGCAATACTGGAGAGATAACGCTGAGGTATGGGTCCCAGGACCTCTCGAATTGGAGCCACTCGGAAATC
CAGCGGTAGAGTTTCGAAAACTTCCGAACGGTTCCCGGAATACGCTCTCGGCCCTCTAACCGAAGAGTTCCGAATATTCCCGAGCGTTGA
GCGAATTTTCGGCGGAAGCAGCCGAACATCATCGAGCCGCCTCGGAGGTGGGGACCGACAACTCCTGTCGTGCCCGCCCGGAGAGGAAGC
GGAAATGCGTGTACGGTATTAAAGGCGTCGCCTCGCCCCTCGCCTTCCTCTTTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCA
TGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATA
ACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCG
TGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATGTGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCA
GCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCATGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATTA
AAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAGATAATACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAATC
CTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTTGGAGACTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCCG
ATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCATCATTGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGACT
TGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAAGTCGTTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACAT
TCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCTAGCTGTAGAAATGTATCCTGATAAACATTAAACACTGTAATCT
TAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTGTAGTGAGAAACTGATTTATGATCACTTGGAAGATTTGTATAGT
TTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGCCAGACTTAAATCACAGATGGGTATTAAACTTGTCAGAATTTCT

>76385_76385_1_RPL28-SOD1_RPL28_chr19_55899416_ENST00000344063_SOD1_chr21_33036103_ENST00000270142_length(amino acids)=299AA_BP=169
MSEFSAEAAEHHRAASEVGTDNSCRARPERKRKCVYGIKGVASPLAFLFPSQVAAAKGAAAMSAHLQWMVVRNCSSFLIKRNKQTYSTEP
NNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNKYRPDLRMESNGPVKVWGS
IKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKAD

--------------------------------------------------------------
>76385_76385_2_RPL28-SOD1_RPL28_chr19_55899416_ENST00000344063_SOD1_chr21_33036103_ENST00000389995_length(transcript)=1699nt_BP=953nt
GGGAGGGCGAACTGCAAGAGGGCTGCCAGGATTAGCCGAGGGATTCCGAATGAAGACGGAGTATTTCCGAACATACACACCTCTCCCAAG
AGCGTTTCCGGAGGGTTCCGAAAATACCCGAGCGGGCCTCGGCGCCCTCATTGGCCATCACCGCGAGGGCTTACGAAGACCGGAAATATC
CAAAGGTGCCGGGGCTAGGCTTATATAGTTCACGCATTCACCAGTTCATTCATAAAACAAATGTTTGTTGAGCGCCCATCATATGCCAAT
CACAGTGACAAGTGCTGGGTGAGCAATACTGGAGAGATAACGCTGAGGTATGGGTCCCAGGACCTCTCGAATTGGAGCCACTCGGAAATC
CAGCGGTAGAGTTTCGAAAACTTCCGAACGGTTCCCGGAATACGCTCTCGGCCCTCTAACCGAAGAGTTCCGAATATTCCCGAGCGTTGA
GCGAATTTTCGGCGGAAGCAGCCGAACATCATCGAGCCGCCTCGGAGGTGGGGACCGACAACTCCTGTCGTGCCCGCCCGGAGAGGAAGC
GGAAATGCGTGTACGGTATTAAAGGCGTCGCCTCGCCCCTCGCCTTCCTCTTTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCA
TGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATA
ACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCG
TGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATGTGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCA
GCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCATGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATTA
AAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAGATAATACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAATC
CTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTTGGAGACTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCCG
ATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCATCATTGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGACT
TGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAAGTCGTTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACAT
TCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCTAGCTGTAGAAATGTATCCTGATAAACATTAAACACTGTAATCT
TAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTGTAGTGAGAAACTGATTTATGATCACTTGGAAGATTTGTATAGT
TTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGCCAGACTTAAATCACAGATGGGTATTAAACTTGTCAGAATTTCT

>76385_76385_2_RPL28-SOD1_RPL28_chr19_55899416_ENST00000344063_SOD1_chr21_33036103_ENST00000389995_length(amino acids)=299AA_BP=169
MSEFSAEAAEHHRAASEVGTDNSCRARPERKRKCVYGIKGVASPLAFLFPSQVAAAKGAAAMSAHLQWMVVRNCSSFLIKRNKQTYSTEP
NNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNKYRPDLRMESNGPVKVWGS
IKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKAD

--------------------------------------------------------------
>76385_76385_3_RPL28-SOD1_RPL28_chr19_55899416_ENST00000458349_SOD1_chr21_33036103_ENST00000270142_length(transcript)=1070nt_BP=324nt
ATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAAT
AACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTC
GTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATGTGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTC
AGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCATGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATT
AAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAGATAATACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAAT
CCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTTGGAGACTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCC
GATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCATCATTGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGAC
TTGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAAGTCGTTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACA
TTCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCTAGCTGTAGAAATGTATCCTGATAAACATTAAACACTGTAATC
TTAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTGTAGTGAGAAACTGATTTATGATCACTTGGAAGATTTGTATAG
TTTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGCCAGACTTAAATCACAGATGGGTATTAAACTTGTCAGAATTTC

>76385_76385_3_RPL28-SOD1_RPL28_chr19_55899416_ENST00000458349_SOD1_chr21_33036103_ENST00000270142_length(amino acids)=238AA_BP=108
MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL
SSIRHMIRKNKYRPDLRMESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVA

--------------------------------------------------------------
>76385_76385_4_RPL28-SOD1_RPL28_chr19_55899416_ENST00000458349_SOD1_chr21_33036103_ENST00000389995_length(transcript)=1070nt_BP=324nt
ATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAAT
AACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTC
GTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATGTGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTC
AGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCATGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATT
AAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAGATAATACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAAT
CCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTTGGAGACTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCC
GATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCATCATTGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGAC
TTGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAAGTCGTTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACA
TTCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCTAGCTGTAGAAATGTATCCTGATAAACATTAAACACTGTAATC
TTAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTGTAGTGAGAAACTGATTTATGATCACTTGGAAGATTTGTATAG
TTTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGCCAGACTTAAATCACAGATGGGTATTAAACTTGTCAGAATTTC

>76385_76385_4_RPL28-SOD1_RPL28_chr19_55899416_ENST00000458349_SOD1_chr21_33036103_ENST00000389995_length(amino acids)=238AA_BP=108
MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL
SSIRHMIRKNKYRPDLRMESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVA

--------------------------------------------------------------
>76385_76385_5_RPL28-SOD1_RPL28_chr19_55899416_ENST00000558815_SOD1_chr21_33036103_ENST00000270142_length(transcript)=1112nt_BP=366nt
CTCTTTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTC
CTGATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGC
AAGACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCC
TATGTGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCAGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTG
CGCATGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATTAAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGA
GATAATACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAATCCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTT
GGAGACTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCCGATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGC
ATCATTGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGACTTGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGA
AGTCGTTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACATTCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCT
AGCTGTAGAAATGTATCCTGATAAACATTAAACACTGTAATCTTAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTG
TAGTGAGAAACTGATTTATGATCACTTGGAAGATTTGTATAGTTTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGC
CAGACTTAAATCACAGATGGGTATTAAACTTGTCAGAATTTCTTTGTCATTCAAGCCTGTGAATAAAAACCCTGTATGGCACTTATTATG

>76385_76385_5_RPL28-SOD1_RPL28_chr19_55899416_ENST00000558815_SOD1_chr21_33036103_ENST00000270142_length(amino acids)=238AA_BP=108
MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL
SSIRHMIRKNKYRPDLRMESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVA

--------------------------------------------------------------
>76385_76385_6_RPL28-SOD1_RPL28_chr19_55899416_ENST00000558815_SOD1_chr21_33036103_ENST00000389995_length(transcript)=1112nt_BP=366nt
CTCTTTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTC
CTGATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGC
AAGACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCC
TATGTGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCAGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTG
CGCATGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATTAAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGA
GATAATACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAATCCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTT
GGAGACTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCCGATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGC
ATCATTGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGACTTGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGA
AGTCGTTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACATTCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCT
AGCTGTAGAAATGTATCCTGATAAACATTAAACACTGTAATCTTAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTG
TAGTGAGAAACTGATTTATGATCACTTGGAAGATTTGTATAGTTTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGC
CAGACTTAAATCACAGATGGGTATTAAACTTGTCAGAATTTCTTTGTCATTCAAGCCTGTGAATAAAAACCCTGTATGGCACTTATTATG

>76385_76385_6_RPL28-SOD1_RPL28_chr19_55899416_ENST00000558815_SOD1_chr21_33036103_ENST00000389995_length(amino acids)=238AA_BP=108
MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL
SSIRHMIRKNKYRPDLRMESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVA

--------------------------------------------------------------
>76385_76385_7_RPL28-SOD1_RPL28_chr19_55899416_ENST00000559463_SOD1_chr21_33036103_ENST00000270142_length(transcript)=1467nt_BP=721nt
GGGAGGTGAGCGTTCGTCTTCCTCGCGTGGTCGCCATCTCCGGCCCGCCGCGCACTCCCTCTCAGTCCTCTGCCTGCCTTCTCCCCTTGC
GCCTCAAGGGTCATTGGCGGACCCCAACCCCTCCCCGTGAAGTCGTTGTGAATTTTCAAGTTATTTTCCCCTCACTCTCATTCGCCGCAG
CTAGTCTCGGCTGCCTGAATTCGGTCCCGCCGCCTTAGGTCACTCAGTCCCGCCTGACAAGAGTTCTAGGTCGCTGTCTGCCCTCAGGGG
TCTCCCATTCACCCAAGTTCCCAGTCGCTCTCTTCCTCTGCTGTCCGAGCGTGGCCCGTGGCCTAACGCTGCTTTAGTTCTCTGTGTCTG
ACGCTTTCCCTGTGCCCGTTTCCCCGCAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGAT
CAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGAC
TGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATGT
GCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCAGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCAT
GGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATTAAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAGATAA
TACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAATCCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTTGGAGA
CTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCCGATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCATCAT
TGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGACTTGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAAGTCG
TTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACATTCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCTAGCTG
TAGAAATGTATCCTGATAAACATTAAACACTGTAATCTTAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTGTAGTG
AGAAACTGATTTATGATCACTTGGAAGATTTGTATAGTTTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGCCAGAC
TTAAATCACAGATGGGTATTAAACTTGTCAGAATTTCTTTGTCATTCAAGCCTGTGAATAAAAACCCTGTATGGCACTTATTATGAGGCT

>76385_76385_7_RPL28-SOD1_RPL28_chr19_55899416_ENST00000559463_SOD1_chr21_33036103_ENST00000270142_length(amino acids)=238AA_BP=108
MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL
SSIRHMIRKNKYRPDLRMESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVA

--------------------------------------------------------------
>76385_76385_8_RPL28-SOD1_RPL28_chr19_55899416_ENST00000559463_SOD1_chr21_33036103_ENST00000389995_length(transcript)=1467nt_BP=721nt
GGGAGGTGAGCGTTCGTCTTCCTCGCGTGGTCGCCATCTCCGGCCCGCCGCGCACTCCCTCTCAGTCCTCTGCCTGCCTTCTCCCCTTGC
GCCTCAAGGGTCATTGGCGGACCCCAACCCCTCCCCGTGAAGTCGTTGTGAATTTTCAAGTTATTTTCCCCTCACTCTCATTCGCCGCAG
CTAGTCTCGGCTGCCTGAATTCGGTCCCGCCGCCTTAGGTCACTCAGTCCCGCCTGACAAGAGTTCTAGGTCGCTGTCTGCCCTCAGGGG
TCTCCCATTCACCCAAGTTCCCAGTCGCTCTCTTCCTCTGCTGTCCGAGCGTGGCCCGTGGCCTAACGCTGCTTTAGTTCTCTGTGTCTG
ACGCTTTCCCTGTGCCCGTTTCCCCGCAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGAT
CAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGAC
TGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATGT
GCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCAGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCAT
GGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATTAAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAGATAA
TACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAATCCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTTGGAGA
CTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCCGATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCATCAT
TGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGACTTGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAAGTCG
TTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACATTCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCTAGCTG
TAGAAATGTATCCTGATAAACATTAAACACTGTAATCTTAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTGTAGTG
AGAAACTGATTTATGATCACTTGGAAGATTTGTATAGTTTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGCCAGAC
TTAAATCACAGATGGGTATTAAACTTGTCAGAATTTCTTTGTCATTCAAGCCTGTGAATAAAAACCCTGTATGGCACTTATTATGAGGCT

>76385_76385_8_RPL28-SOD1_RPL28_chr19_55899416_ENST00000559463_SOD1_chr21_33036103_ENST00000389995_length(amino acids)=238AA_BP=108
MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL
SSIRHMIRKNKYRPDLRMESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVA

--------------------------------------------------------------
>76385_76385_9_RPL28-SOD1_RPL28_chr19_55899416_ENST00000560055_SOD1_chr21_33036103_ENST00000270142_length(transcript)=1108nt_BP=362nt
TTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGA
TCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGA
CTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATG
TGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCAGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCA
TGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATTAAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAGATA
ATACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAATCCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTTGGAG
ACTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCCGATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCATCA
TTGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGACTTGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAAGTC
GTTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACATTCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCTAGCT
GTAGAAATGTATCCTGATAAACATTAAACACTGTAATCTTAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTGTAGT
GAGAAACTGATTTATGATCACTTGGAAGATTTGTATAGTTTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGCCAGA
CTTAAATCACAGATGGGTATTAAACTTGTCAGAATTTCTTTGTCATTCAAGCCTGTGAATAAAAACCCTGTATGGCACTTATTATGAGGC

>76385_76385_9_RPL28-SOD1_RPL28_chr19_55899416_ENST00000560055_SOD1_chr21_33036103_ENST00000270142_length(amino acids)=238AA_BP=108
MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL
SSIRHMIRKNKYRPDLRMESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVA

--------------------------------------------------------------
>76385_76385_10_RPL28-SOD1_RPL28_chr19_55899416_ENST00000560055_SOD1_chr21_33036103_ENST00000389995_length(transcript)=1108nt_BP=362nt
TTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGA
TCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGA
CTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATG
TGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCAGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCA
TGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATTAAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAGATA
ATACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAATCCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTTGGAG
ACTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCCGATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCATCA
TTGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGACTTGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAAGTC
GTTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACATTCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCTAGCT
GTAGAAATGTATCCTGATAAACATTAAACACTGTAATCTTAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTGTAGT
GAGAAACTGATTTATGATCACTTGGAAGATTTGTATAGTTTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGCCAGA
CTTAAATCACAGATGGGTATTAAACTTGTCAGAATTTCTTTGTCATTCAAGCCTGTGAATAAAAACCCTGTATGGCACTTATTATGAGGC

>76385_76385_10_RPL28-SOD1_RPL28_chr19_55899416_ENST00000560055_SOD1_chr21_33036103_ENST00000389995_length(amino acids)=238AA_BP=108
MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL
SSIRHMIRKNKYRPDLRMESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVA

--------------------------------------------------------------
>76385_76385_11_RPL28-SOD1_RPL28_chr19_55899416_ENST00000560583_SOD1_chr21_33036103_ENST00000270142_length(transcript)=1831nt_BP=1085nt
CTTTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCT
GATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAA
GACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGTGAGCTGGGGTTTGGGGATCAGGC
TTGGGGAGACTGGCCAGTGCTGTGGGGAAGGGCCTCCCACTACTGGTTGCAATATGGGCTGGAGAGGGATGGATTCTTGCTTTCAGCCTA
CTCCCCACACCCAGCATTGGCCTAGGGGGCGGCTTGTGGAGTGTATGGGCTGAGCCTTGCTCTGCTCCCCCGCCCCCAGGCAGCCATCCG
CAGGGCCAGCGCCATCCTGCGCAGCCAGAAGCCTGTGATGGTGAAGAGGAAGCGGACCCGCCCCACCAAGAGCTCCTGAGCCCCCTGCCC
CCAGAGCAATAAAGTCAGCTGGCTTTCTCACCTGCCTCGACTGGGCCTCCCTTTTTGAAACGCTCTGGGGAGCTCTGGCCCTGTGTGTTG
TCATTCAGGCCATGTCATCAAAACTCTGCATGTCACCTTGTCCATCTGGAGGTGATGTCAATGGCTGGCCATGCAGGAGGGGTGGGGTAG
CTGCCTTGTCCCTGGTGAGGGCAAGGGTCACTGTCTTCACAGAAAAAGTTTGCTGACTTGTGATTGAGACCTACTGTCCCATTGTGAGGT
GGCCTGAAGAATCCCAGCTGGGGCAGTGGCTTCCATTCAGAAGAAGAAAGGCCTTTTCTAGCCCAGAAGGGTGCAGGCTGAGGGCTGGGC
CCTGGGCCCTGGTGCTGTAGCACGGTTTGGGGACTTGGGGTGTTCCCAAGACCTGGGGGACGACAGACATCACGGGAGGAAGATGAGATG
ACTTTTGCATCCAGGGAGTGGGTGCAGCCACATTTGGAGGGGATGGGCTTTACTTGATGCAACCTCATCTCTGAGATGGGCAACTTGGTG
GGTGGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATTAAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAG
ATAATACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAATCCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTTG
GAGACTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCCGATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCA
TCATTGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGACTTGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAA
GTCGTTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACATTCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCTA
GCTGTAGAAATGTATCCTGATAAACATTAAACACTGTAATCTTAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTGT
AGTGAGAAACTGATTTATGATCACTTGGAAGATTTGTATAGTTTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGCC
AGACTTAAATCACAGATGGGTATTAAACTTGTCAGAATTTCTTTGTCATTCAAGCCTGTGAATAAAAACCCTGTATGGCACTTATTATGA

>76385_76385_11_RPL28-SOD1_RPL28_chr19_55899416_ENST00000560583_SOD1_chr21_33036103_ENST00000270142_length(amino acids)=165AA_BP=0
MNMESMQAFSQSFNASPHLHWSITFPPTKLPISEMRLHQVKPIPSKCGCTHSLDAKVISSSSRDVCRPPGLGNTPSPQTVLQHQGPGPSP

--------------------------------------------------------------
>76385_76385_12_RPL28-SOD1_RPL28_chr19_55899416_ENST00000560583_SOD1_chr21_33036103_ENST00000389995_length(transcript)=1831nt_BP=1085nt
CTTTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCT
GATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAA
GACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGTGAGCTGGGGTTTGGGGATCAGGC
TTGGGGAGACTGGCCAGTGCTGTGGGGAAGGGCCTCCCACTACTGGTTGCAATATGGGCTGGAGAGGGATGGATTCTTGCTTTCAGCCTA
CTCCCCACACCCAGCATTGGCCTAGGGGGCGGCTTGTGGAGTGTATGGGCTGAGCCTTGCTCTGCTCCCCCGCCCCCAGGCAGCCATCCG
CAGGGCCAGCGCCATCCTGCGCAGCCAGAAGCCTGTGATGGTGAAGAGGAAGCGGACCCGCCCCACCAAGAGCTCCTGAGCCCCCTGCCC
CCAGAGCAATAAAGTCAGCTGGCTTTCTCACCTGCCTCGACTGGGCCTCCCTTTTTGAAACGCTCTGGGGAGCTCTGGCCCTGTGTGTTG
TCATTCAGGCCATGTCATCAAAACTCTGCATGTCACCTTGTCCATCTGGAGGTGATGTCAATGGCTGGCCATGCAGGAGGGGTGGGGTAG
CTGCCTTGTCCCTGGTGAGGGCAAGGGTCACTGTCTTCACAGAAAAAGTTTGCTGACTTGTGATTGAGACCTACTGTCCCATTGTGAGGT
GGCCTGAAGAATCCCAGCTGGGGCAGTGGCTTCCATTCAGAAGAAGAAAGGCCTTTTCTAGCCCAGAAGGGTGCAGGCTGAGGGCTGGGC
CCTGGGCCCTGGTGCTGTAGCACGGTTTGGGGACTTGGGGTGTTCCCAAGACCTGGGGGACGACAGACATCACGGGAGGAAGATGAGATG
ACTTTTGCATCCAGGGAGTGGGTGCAGCCACATTTGGAGGGGATGGGCTTTACTTGATGCAACCTCATCTCTGAGATGGGCAACTTGGTG
GGTGGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATTAAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAG
ATAATACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAATCCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTTG
GAGACTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCCGATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCA
TCATTGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGACTTGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAA
GTCGTTTGGCTTGTGGTGTAATTGGGATCGCCCAATAAACATTCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTTATCCTGCTA
GCTGTAGAAATGTATCCTGATAAACATTAAACACTGTAATCTTAAAAGTGTAATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTGT
AGTGAGAAACTGATTTATGATCACTTGGAAGATTTGTATAGTTTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTGTATTTTGCC
AGACTTAAATCACAGATGGGTATTAAACTTGTCAGAATTTCTTTGTCATTCAAGCCTGTGAATAAAAACCCTGTATGGCACTTATTATGA

>76385_76385_12_RPL28-SOD1_RPL28_chr19_55899416_ENST00000560583_SOD1_chr21_33036103_ENST00000389995_length(amino acids)=165AA_BP=0
MNMESMQAFSQSFNASPHLHWSITFPPTKLPISEMRLHQVKPIPSKCGCTHSLDAKVISSSSRDVCRPPGLGNTPSPQTVLQHQGPGPSP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RPL28-SOD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RPL28-SOD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RPL28-SOD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource