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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RPL5-CCDC18 (FusionGDB2 ID:76913)

Fusion Gene Summary for RPL5-CCDC18

check button Fusion gene summary
Fusion gene informationFusion gene name: RPL5-CCDC18
Fusion gene ID: 76913
HgeneTgene
Gene symbol

RPL5

CCDC18

Gene ID

6125

343099

Gene nameribosomal protein L5coiled-coil domain containing 18
SynonymsL5|MSTP030|PPP1R135|uL18NY-SAR-41
Cytomap

1p22.1

1p22.1

Type of geneprotein-codingprotein-coding
Description60S ribosomal protein L5large ribosomal subunit protein uL18protein phosphatase 1, regulatory subunit 135coiled-coil domain-containing protein 18sarcoma antigen NY-SAR-24sarcoma antigen NY-SAR-41
Modification date2020031320200313
UniProtAcc.

A1A4V9

Ensembl transtripts involved in fusion geneENST00000370321, ENST00000334652, 
ENST00000338949, ENST00000557479, 
ENST00000421014, ENST00000343253, 
ENST00000401026, 
Fusion gene scores* DoF score17 X 7 X 9=10717 X 12 X 5=420
# samples 2011
** MAII scorelog2(20/1071*10)=-2.42088657497553
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/420*10)=-1.93288580414146
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RPL5 [Title/Abstract] AND CCDC18 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRPL5(93300470)-CCDC18(93657557), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRPL5

GO:0010628

positive regulation of gene expression

18560357

HgeneRPL5

GO:0045727

positive regulation of translation

16213212

HgeneRPL5

GO:1904667

negative regulation of ubiquitin protein ligase activity

18560357

HgeneRPL5

GO:2000059

negative regulation of ubiquitin-dependent protein catabolic process

18560357

HgeneRPL5

GO:2000435

negative regulation of protein neddylation

18560357


check buttonFusion gene breakpoints across RPL5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CCDC18 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-FD-A3SP-01ARPL5chr1

93300470

+CCDC18chr1

93657557

+
ChimerDB4BLCATCGA-FD-A3SPRPL5chr1

93300470

+CCDC18chr1

93657556

+
ChimerDB4KIRCTCGA-CJ-4868-01ARPL5chr1

93303190

+CCDC18chr1

93687166

+


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Fusion Gene ORF analysis for RPL5-CCDC18

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000370321ENST00000334652RPL5chr1

93300470

+CCDC18chr1

93657557

+
5CDS-5UTRENST00000370321ENST00000334652RPL5chr1

93300470

+CCDC18chr1

93657556

+
5CDS-5UTRENST00000370321ENST00000334652RPL5chr1

93303190

+CCDC18chr1

93687166

+
5CDS-5UTRENST00000370321ENST00000338949RPL5chr1

93300470

+CCDC18chr1

93657557

+
5CDS-5UTRENST00000370321ENST00000338949RPL5chr1

93300470

+CCDC18chr1

93657556

+
5CDS-5UTRENST00000370321ENST00000557479RPL5chr1

93300470

+CCDC18chr1

93657557

+
5CDS-5UTRENST00000370321ENST00000557479RPL5chr1

93300470

+CCDC18chr1

93657556

+
5CDS-5UTRENST00000370321ENST00000557479RPL5chr1

93303190

+CCDC18chr1

93687166

+
5CDS-intronENST00000370321ENST00000421014RPL5chr1

93300470

+CCDC18chr1

93657557

+
5CDS-intronENST00000370321ENST00000421014RPL5chr1

93300470

+CCDC18chr1

93657556

+
5CDS-intronENST00000370321ENST00000421014RPL5chr1

93303190

+CCDC18chr1

93687166

+
In-frameENST00000370321ENST00000338949RPL5chr1

93303190

+CCDC18chr1

93687166

+
In-frameENST00000370321ENST00000343253RPL5chr1

93300470

+CCDC18chr1

93657557

+
In-frameENST00000370321ENST00000343253RPL5chr1

93300470

+CCDC18chr1

93657556

+
In-frameENST00000370321ENST00000343253RPL5chr1

93303190

+CCDC18chr1

93687166

+
In-frameENST00000370321ENST00000401026RPL5chr1

93300470

+CCDC18chr1

93657557

+
In-frameENST00000370321ENST00000401026RPL5chr1

93300470

+CCDC18chr1

93657556

+
In-frameENST00000370321ENST00000401026RPL5chr1

93303190

+CCDC18chr1

93687166

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000370321RPL5chr193300470+ENST00000343253CCDC18chr193657557+43174145443161420
ENST00000370321RPL5chr193300470+ENST00000401026CCDC18chr193657557+39824145438511265
ENST00000370321RPL5chr193303190+ENST00000343253CCDC18chr193687166+32017955432001048
ENST00000370321RPL5chr193303190+ENST00000401026CCDC18chr193687166+2863795542732892
ENST00000370321RPL5chr193303190+ENST00000338949CCDC18chr193687166+2969795542732892
ENST00000370321RPL5chr193300470+ENST00000343253CCDC18chr193657556+43174145443161420
ENST00000370321RPL5chr193300470+ENST00000401026CCDC18chr193657556+39824145438511265

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000370321ENST00000343253RPL5chr193300470+CCDC18chr193657557+0.0035688890.9964311
ENST00000370321ENST00000401026RPL5chr193300470+CCDC18chr193657557+0.0015258710.9984742
ENST00000370321ENST00000343253RPL5chr193303190+CCDC18chr193687166+0.0018951820.9981048
ENST00000370321ENST00000401026RPL5chr193303190+CCDC18chr193687166+0.0025764080.99742365
ENST00000370321ENST00000338949RPL5chr193303190+CCDC18chr193687166+0.0020504620.99794954
ENST00000370321ENST00000343253RPL5chr193300470+CCDC18chr193657556+0.0035688890.9964311
ENST00000370321ENST00000401026RPL5chr193300470+CCDC18chr193657556+0.0015258710.9984742

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Fusion Genomic Features for RPL5-CCDC18


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RPL5chr193303190+CCDC18chr193687165+0.0001441440.9998559
RPL5chr193300470+CCDC18chr193657556+6.98E-050.99993014
RPL5chr193300470+CCDC18chr193657556+6.98E-050.99993014
RPL5chr193303190+CCDC18chr193687165+0.0001441440.9998559
RPL5chr193300470+CCDC18chr193657556+6.98E-050.99993014
RPL5chr193300470+CCDC18chr193657556+6.98E-050.99993014

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for RPL5-CCDC18


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:93300470/chr1:93657557)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CCDC18

A1A4V9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCCDC18chr1:93300470chr1:93657556ENST00000343253329170_4021541455.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC18chr1:93300470chr1:93657556ENST00000343253329438_4641541455.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC18chr1:93300470chr1:93657556ENST00000343253329508_13091541455.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC18chr1:93300470chr1:93657557ENST00000343253329170_4021541455.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC18chr1:93300470chr1:93657557ENST00000343253329438_4641541455.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC18chr1:93300470chr1:93657557ENST00000343253329508_13091541455.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCCDC18chr1:93300470chr1:93657556ENST00000343253329107_1381541455.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC18chr1:93300470chr1:93657557ENST00000343253329107_1381541455.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC18chr1:93303190chr1:93687166ENST000003432531329107_1386531455.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC18chr1:93303190chr1:93687166ENST000003432531329170_4026531455.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC18chr1:93303190chr1:93687166ENST000003432531329438_4646531455.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC18chr1:93303190chr1:93687166ENST000003432531329508_13096531455.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for RPL5-CCDC18


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>76913_76913_1_RPL5-CCDC18_RPL5_chr1_93300470_ENST00000370321_CCDC18_chr1_93657556_ENST00000343253_length(transcript)=4317nt_BP=414nt
CGCAAGGGCTGTGGCCCTTTTCCCACCCCCTAGCGCCGCTGGGCCTGCAGGTCTCTGTCGAGCAGCGGACGCCGGTCTCTGTTCCGCAGG
ATGGGGTTTGTTAAAGTTGTTAAGAATAAGGCCTACTTTAAGAGATACCAAGTGAAATTTAGAAGACGACGAGAGGGTAAAACTGATTAT
TATGCTCGGAAACGCTTGGTGATACAAGATAAAAATAAATACAACACACCCAAATACAGGATGATAGTTCGTGTGACAAACAGAGATATC
ATTTGTCAGATTGCTTATGCCCGTATAGAGGGGGATATGATAGTCTGCGCAGCGTATGCACACGAACTGCCAAAATATGGTGTGAAGGTT
GGCCTGACAAATTATGCTGCAGCATATTGTACTGGCCTGCTGCTGGCCCGCAGGGTTTCTATGCTTGAGTCTGCTCAACAGCAGGCAGCC
AGTGTCCCAATCTTAGAAGAACAGATTATAAATTTGGAAGCAGAGGTTTCAGCTCAAGATAAAGTTTTGAGAGAGGCAGAAAATAAGCTG
GAACAGAGCCAGAAAATGGTAATTGAAAAGGAACAGAGTTTGCAGGAGTCCAAAGAGGAATGTATAAAATTAAAGGTGGACTTACTTGAA
CAAACCAAACAAGGAAAAAGAGCTGAACGACAAAGGAATGAAGCACTATATAATGCCGAAGAGCTGAGTAAAGCTTTCCAACAATATAAA
AAAAAAGTGGCTGAAAAACTGGAAAAGGTTCAAGCTGAAGAAGAAATATTAGAGAGAAATCTAACTAACTGTGAAAAAGAAAATAAAAGG
CTACAAGAAAGGTGTGGTCTATATAAAAGTGAACTTGAAATTCTGAAAGAGAAATTAAGGCAGTTAAAAGAAGAAAATAACAACGGAAAA
GAAAAATTAAGGATCATGGCAGTGAAAAATTCAGAAGTCATGGCACAACTAACTGAATCTAGACAAAGTATTTTGAAGCTAGAGAGTGAG
TTAGAGAACAAAGACGAAATACTTAGAGACAAATTTTCTTTAATGAATGAAAACCGAGAATTAAAGGTCCGTGTTGCAGCACAGAATGAG
CGACTAGATTTATGTCAACAAGAAATTGAAAGTTCAAGGGTAGAACTAAGAAGTTTGGAAAAGATTATATCCCAGTTGCCATTAAAAAGA
GAATTATTTGGCTTTAAATCATATCTTTCTAAATACCAGATGAGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCA
AATAAATTGGTGATTTCGGAATTGAGAATTAAGCTTGCAATAAAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAG
TTATCTCAGAGTCTTATTACTTGTAATGACAGCCAAGAAAGTAGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCAT
CAAGTAGAAAGCGTAAAAGATCAAAATCAACATACTATGAACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAA
CTACGTACTAAGCTGATACAAATAGAAGCTGAAAATTCTGATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAA
GAGGAGCTGCTAGAGAAAGCTTCAAACTCCAGCAAACTGGAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAG
CTGGAAGAAAAGATAGTTGCTTATTCCTCTATTGCTGCAAAAAATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATAAGG
AGTCTAGAAACCAATATTAATACAGAGCATGAGAAAATTTGTTTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAAGAA
ATGGAAAAGCAGATTGAAAGACTTGAAGCTCAACTAGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAA
CAAGATATAATATGCAAACAACATCATCTTGAATCACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAG
AAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAG
GAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGT
TTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAG
CAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAA
CTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGG
CAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAA
ATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAA
AAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTT
GAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTA
TCATTAGAGGAAAAATACACTACTATAAAGGATCTCACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTC
CTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAG
CACAGAGGAGAAATGGAACAAAAAATAATTAAATTAGAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATA
GAAAGTCTGAATGACAAATTACAAAATGCTAAAGAACAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAA
CTGAAAAAAGAAATTGAAAGAACACAACAAAGGATGAAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTAC
AAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTGACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAG
CAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCTAGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAAC
CATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGTGAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAA
GTAGAATCTCTCAAAGAAGCTTATCATATGGAGATGATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAG
TCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAGGCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAA
GTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAATGAAGCATTACTTACTAAAGAATCAGAATTAACCAGATTACAGGCCAAAATTTCT
GGACATGAAAAGGCAGAAGACATCAAGTTTCTGCCAGCCCCATTTACATCTCCAACAGAAATTATGCCTGATGTTCAAGATCCAAAATTT
GCTAAATGTTTTCACACATCTTTTTCCAAGTGTACAAAATTACGTCGCTCTATTAGTGCCAGTGATCTTACTTTCAAAATTCATGGTGAT
GAAGATCTTTCTGAAGAATTACTACAGGACTTAAAGAAAATGCAATTAGAACAGCCTTCAACATTAGAAGAAAGCCATAAGAATCTGACT
TACACCCAGCCAGACTCATTTAAACCTCTCACATATAACCTAGAAGCTGATAGTTCTGAGAATAATGACTTTAACACGCTTAGTGGGATG

>76913_76913_1_RPL5-CCDC18_RPL5_chr1_93300470_ENST00000370321_CCDC18_chr1_93657556_ENST00000343253_length(amino acids)=1420AA_BP=13
MSSSGRRSLFRRMGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAA
YAHELPKYGVKVGLTNYAAAYCTGLLLARRVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESK
EECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEK
LRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRS
LEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLS
SLETEPVKLGGHQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMT
KKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQ
FKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFE
KQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEK
CESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTET
ELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRA
AQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESV
MKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEA
RMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTK
ESELTRLQAKISGHEKAEDIKFLPAPFTSPTEIMPDVQDPKFAKCFHTSFSKCTKLRRSISASDLTFKIHGDEDLSEELLQDLKKMQLEQ

--------------------------------------------------------------
>76913_76913_2_RPL5-CCDC18_RPL5_chr1_93300470_ENST00000370321_CCDC18_chr1_93657556_ENST00000401026_length(transcript)=3982nt_BP=414nt
CGCAAGGGCTGTGGCCCTTTTCCCACCCCCTAGCGCCGCTGGGCCTGCAGGTCTCTGTCGAGCAGCGGACGCCGGTCTCTGTTCCGCAGG
ATGGGGTTTGTTAAAGTTGTTAAGAATAAGGCCTACTTTAAGAGATACCAAGTGAAATTTAGAAGACGACGAGAGGGTAAAACTGATTAT
TATGCTCGGAAACGCTTGGTGATACAAGATAAAAATAAATACAACACACCCAAATACAGGATGATAGTTCGTGTGACAAACAGAGATATC
ATTTGTCAGATTGCTTATGCCCGTATAGAGGGGGATATGATAGTCTGCGCAGCGTATGCACACGAACTGCCAAAATATGGTGTGAAGGTT
GGCCTGACAAATTATGCTGCAGCATATTGTACTGGCCTGCTGCTGGCCCGCAGGGTTTCTATGCTTGAGTCTGCTCAACAGCAGGCAGCC
AGTGTCCCAATCTTAGAAGAACAGATTATAAATTTGGAAGCAGAGGTTTCAGCTCAAGATAAAGTTTTGAGAGAGGCAGAAAATAAGCTG
GAACAGAGCCAGAAAATGGTAATTGAAAAGGAACAGAGTTTGCAGGAGTCCAAAGAGGAATGTATAAAATTAAAGGTGGACTTACTTGAA
CAAACCAAACAAGGAAAAAGAGCTGAACGACAAAGGAATGAAGCACTATATAATGCCGAAGAGCTGAGTAAAGCTTTCCAACAATATAAA
AAAAAAGTGGCTGAAAAACTGGAAAAGGTTCAAGCTGAAGAAGAAATATTAGAGAGAAATCTAACTAACTGTGAAAAAGAAAATAAAAGG
CTACAAGAAAGGTGTGGTCTATATAAAAGTGAACTTGAAATTCTGAAAGAGAAATTAAGGCAGTTAAAAGAAGAAAATAACAACGGAAAA
GAAAAATTAAGGATCATGGCAGTGAAAAATTCAGAAGTCATGGCACAACTAACTGAATCTAGACAAAGTATTTTGAAGCTAGAGAGTGAG
TTAGAGAACAAAGACGAAATACTTAGAGACAAATTTTCTTTAATGAATGAAAACCGAGAATTAAAGGTCCGTGTTGCAGCACAGAATGAG
CGACTAGATTTATGTCAACAAGAAATTGAAAGTTCAAGGGTAGAACTAAGAAGTTTGGAAAAGATTATATCCCAGTTGCCATTAAAAAGA
GAATTATTTGGCTTTAAATCATATCTTTCTAAATACCAGATGAGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCA
AATAAATTGGTGATTTCGGAATTGAGAATTAAGCTTGCAATAAAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAG
TTATCTCAGAGTCTTATTACTTGTAATGACAGCCAAGAAAGTAGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCAT
CAAGTAGCAGAAAGCGTAAAAGATCAAAATCAACATACTATGAACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAA
GAACTACGTACTAAGCTGATACAAATAGAAGCTGAAAATTCTGATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATT
CAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAGCAAACTGGAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAA
CAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTATTGCTGCAAAAAATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATA
AGGAGTCTAGAAACCAATATTAATACAGAGCATGAGAAAATTTGTTTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAA
GAAATGGAAAAGCAGATTGAAAGACTTGAAGCTCAACTAGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTG
CAACAAGATATAATATGCAAACAACATCATCTTGAATCACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATG
AAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGT
AAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATAT
TGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAG
CAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAA
GAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAA
AGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAG
GAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTA
GAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTA
CTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAA
TTATCATTAGAGGAAAAATACACTACTATAAAGGATCTCACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAG
CTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGT
GAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATTAGAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAG
ATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGAACAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGT
CAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGATGAAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAG
TACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTGACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCAT
CAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCTAGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGA
AACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGTGAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCA
GAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGATGATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAA
AAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAGGCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAA
CAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAATGAAGCATTACTTACTAAAGGAGAAAATGTGTAATTCAAAGAAGATACTGAT
GTGTTGAAAAAATGGAATTTTTGGTACTGTGCTGTTTACTTATTATATGTAGCTCATACTTCATAGAAGCTGTTATTTTGCTTTTGAATA

>76913_76913_2_RPL5-CCDC18_RPL5_chr1_93300470_ENST00000370321_CCDC18_chr1_93657556_ENST00000401026_length(amino acids)=1265AA_BP=13
MSSSGRRSLFRRMGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAA
YAHELPKYGVKVGLTNYAAAYCTGLLLARRVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESK
EECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEK
LRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRS
LEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLS
SLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEM
TKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQ
QFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKF
EKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEE
KCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTE
TELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQR
AAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMES
VMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLE
ARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLT

--------------------------------------------------------------
>76913_76913_3_RPL5-CCDC18_RPL5_chr1_93300470_ENST00000370321_CCDC18_chr1_93657557_ENST00000343253_length(transcript)=4317nt_BP=414nt
CGCAAGGGCTGTGGCCCTTTTCCCACCCCCTAGCGCCGCTGGGCCTGCAGGTCTCTGTCGAGCAGCGGACGCCGGTCTCTGTTCCGCAGG
ATGGGGTTTGTTAAAGTTGTTAAGAATAAGGCCTACTTTAAGAGATACCAAGTGAAATTTAGAAGACGACGAGAGGGTAAAACTGATTAT
TATGCTCGGAAACGCTTGGTGATACAAGATAAAAATAAATACAACACACCCAAATACAGGATGATAGTTCGTGTGACAAACAGAGATATC
ATTTGTCAGATTGCTTATGCCCGTATAGAGGGGGATATGATAGTCTGCGCAGCGTATGCACACGAACTGCCAAAATATGGTGTGAAGGTT
GGCCTGACAAATTATGCTGCAGCATATTGTACTGGCCTGCTGCTGGCCCGCAGGGTTTCTATGCTTGAGTCTGCTCAACAGCAGGCAGCC
AGTGTCCCAATCTTAGAAGAACAGATTATAAATTTGGAAGCAGAGGTTTCAGCTCAAGATAAAGTTTTGAGAGAGGCAGAAAATAAGCTG
GAACAGAGCCAGAAAATGGTAATTGAAAAGGAACAGAGTTTGCAGGAGTCCAAAGAGGAATGTATAAAATTAAAGGTGGACTTACTTGAA
CAAACCAAACAAGGAAAAAGAGCTGAACGACAAAGGAATGAAGCACTATATAATGCCGAAGAGCTGAGTAAAGCTTTCCAACAATATAAA
AAAAAAGTGGCTGAAAAACTGGAAAAGGTTCAAGCTGAAGAAGAAATATTAGAGAGAAATCTAACTAACTGTGAAAAAGAAAATAAAAGG
CTACAAGAAAGGTGTGGTCTATATAAAAGTGAACTTGAAATTCTGAAAGAGAAATTAAGGCAGTTAAAAGAAGAAAATAACAACGGAAAA
GAAAAATTAAGGATCATGGCAGTGAAAAATTCAGAAGTCATGGCACAACTAACTGAATCTAGACAAAGTATTTTGAAGCTAGAGAGTGAG
TTAGAGAACAAAGACGAAATACTTAGAGACAAATTTTCTTTAATGAATGAAAACCGAGAATTAAAGGTCCGTGTTGCAGCACAGAATGAG
CGACTAGATTTATGTCAACAAGAAATTGAAAGTTCAAGGGTAGAACTAAGAAGTTTGGAAAAGATTATATCCCAGTTGCCATTAAAAAGA
GAATTATTTGGCTTTAAATCATATCTTTCTAAATACCAGATGAGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCA
AATAAATTGGTGATTTCGGAATTGAGAATTAAGCTTGCAATAAAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAG
TTATCTCAGAGTCTTATTACTTGTAATGACAGCCAAGAAAGTAGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCAT
CAAGTAGAAAGCGTAAAAGATCAAAATCAACATACTATGAACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAA
CTACGTACTAAGCTGATACAAATAGAAGCTGAAAATTCTGATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAA
GAGGAGCTGCTAGAGAAAGCTTCAAACTCCAGCAAACTGGAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAG
CTGGAAGAAAAGATAGTTGCTTATTCCTCTATTGCTGCAAAAAATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATAAGG
AGTCTAGAAACCAATATTAATACAGAGCATGAGAAAATTTGTTTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAAGAA
ATGGAAAAGCAGATTGAAAGACTTGAAGCTCAACTAGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAA
CAAGATATAATATGCAAACAACATCATCTTGAATCACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAG
AAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAG
GAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGT
TTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAG
CAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAA
CTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGG
CAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAA
ATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAA
AAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTT
GAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTA
TCATTAGAGGAAAAATACACTACTATAAAGGATCTCACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTC
CTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAG
CACAGAGGAGAAATGGAACAAAAAATAATTAAATTAGAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATA
GAAAGTCTGAATGACAAATTACAAAATGCTAAAGAACAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAA
CTGAAAAAAGAAATTGAAAGAACACAACAAAGGATGAAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTAC
AAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTGACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAG
CAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCTAGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAAC
CATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGTGAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAA
GTAGAATCTCTCAAAGAAGCTTATCATATGGAGATGATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAG
TCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAGGCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAA
GTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAATGAAGCATTACTTACTAAAGAATCAGAATTAACCAGATTACAGGCCAAAATTTCT
GGACATGAAAAGGCAGAAGACATCAAGTTTCTGCCAGCCCCATTTACATCTCCAACAGAAATTATGCCTGATGTTCAAGATCCAAAATTT
GCTAAATGTTTTCACACATCTTTTTCCAAGTGTACAAAATTACGTCGCTCTATTAGTGCCAGTGATCTTACTTTCAAAATTCATGGTGAT
GAAGATCTTTCTGAAGAATTACTACAGGACTTAAAGAAAATGCAATTAGAACAGCCTTCAACATTAGAAGAAAGCCATAAGAATCTGACT
TACACCCAGCCAGACTCATTTAAACCTCTCACATATAACCTAGAAGCTGATAGTTCTGAGAATAATGACTTTAACACGCTTAGTGGGATG

>76913_76913_3_RPL5-CCDC18_RPL5_chr1_93300470_ENST00000370321_CCDC18_chr1_93657557_ENST00000343253_length(amino acids)=1420AA_BP=13
MSSSGRRSLFRRMGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAA
YAHELPKYGVKVGLTNYAAAYCTGLLLARRVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESK
EECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEK
LRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRS
LEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLS
SLETEPVKLGGHQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMT
KKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQ
FKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFE
KQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEK
CESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTET
ELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRA
AQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESV
MKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEA
RMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTK
ESELTRLQAKISGHEKAEDIKFLPAPFTSPTEIMPDVQDPKFAKCFHTSFSKCTKLRRSISASDLTFKIHGDEDLSEELLQDLKKMQLEQ

--------------------------------------------------------------
>76913_76913_4_RPL5-CCDC18_RPL5_chr1_93300470_ENST00000370321_CCDC18_chr1_93657557_ENST00000401026_length(transcript)=3982nt_BP=414nt
CGCAAGGGCTGTGGCCCTTTTCCCACCCCCTAGCGCCGCTGGGCCTGCAGGTCTCTGTCGAGCAGCGGACGCCGGTCTCTGTTCCGCAGG
ATGGGGTTTGTTAAAGTTGTTAAGAATAAGGCCTACTTTAAGAGATACCAAGTGAAATTTAGAAGACGACGAGAGGGTAAAACTGATTAT
TATGCTCGGAAACGCTTGGTGATACAAGATAAAAATAAATACAACACACCCAAATACAGGATGATAGTTCGTGTGACAAACAGAGATATC
ATTTGTCAGATTGCTTATGCCCGTATAGAGGGGGATATGATAGTCTGCGCAGCGTATGCACACGAACTGCCAAAATATGGTGTGAAGGTT
GGCCTGACAAATTATGCTGCAGCATATTGTACTGGCCTGCTGCTGGCCCGCAGGGTTTCTATGCTTGAGTCTGCTCAACAGCAGGCAGCC
AGTGTCCCAATCTTAGAAGAACAGATTATAAATTTGGAAGCAGAGGTTTCAGCTCAAGATAAAGTTTTGAGAGAGGCAGAAAATAAGCTG
GAACAGAGCCAGAAAATGGTAATTGAAAAGGAACAGAGTTTGCAGGAGTCCAAAGAGGAATGTATAAAATTAAAGGTGGACTTACTTGAA
CAAACCAAACAAGGAAAAAGAGCTGAACGACAAAGGAATGAAGCACTATATAATGCCGAAGAGCTGAGTAAAGCTTTCCAACAATATAAA
AAAAAAGTGGCTGAAAAACTGGAAAAGGTTCAAGCTGAAGAAGAAATATTAGAGAGAAATCTAACTAACTGTGAAAAAGAAAATAAAAGG
CTACAAGAAAGGTGTGGTCTATATAAAAGTGAACTTGAAATTCTGAAAGAGAAATTAAGGCAGTTAAAAGAAGAAAATAACAACGGAAAA
GAAAAATTAAGGATCATGGCAGTGAAAAATTCAGAAGTCATGGCACAACTAACTGAATCTAGACAAAGTATTTTGAAGCTAGAGAGTGAG
TTAGAGAACAAAGACGAAATACTTAGAGACAAATTTTCTTTAATGAATGAAAACCGAGAATTAAAGGTCCGTGTTGCAGCACAGAATGAG
CGACTAGATTTATGTCAACAAGAAATTGAAAGTTCAAGGGTAGAACTAAGAAGTTTGGAAAAGATTATATCCCAGTTGCCATTAAAAAGA
GAATTATTTGGCTTTAAATCATATCTTTCTAAATACCAGATGAGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCA
AATAAATTGGTGATTTCGGAATTGAGAATTAAGCTTGCAATAAAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAG
TTATCTCAGAGTCTTATTACTTGTAATGACAGCCAAGAAAGTAGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCAT
CAAGTAGCAGAAAGCGTAAAAGATCAAAATCAACATACTATGAACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAA
GAACTACGTACTAAGCTGATACAAATAGAAGCTGAAAATTCTGATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATT
CAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAGCAAACTGGAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAA
CAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTATTGCTGCAAAAAATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATA
AGGAGTCTAGAAACCAATATTAATACAGAGCATGAGAAAATTTGTTTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAA
GAAATGGAAAAGCAGATTGAAAGACTTGAAGCTCAACTAGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTG
CAACAAGATATAATATGCAAACAACATCATCTTGAATCACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATG
AAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGT
AAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATAT
TGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAG
CAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAA
GAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAA
AGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAG
GAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTA
GAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTA
CTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAA
TTATCATTAGAGGAAAAATACACTACTATAAAGGATCTCACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAG
CTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGT
GAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATTAGAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAG
ATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGAACAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGT
CAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGATGAAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAG
TACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTGACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCAT
CAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCTAGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGA
AACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGTGAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCA
GAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGATGATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAA
AAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAGGCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAA
CAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAATGAAGCATTACTTACTAAAGGAGAAAATGTGTAATTCAAAGAAGATACTGAT
GTGTTGAAAAAATGGAATTTTTGGTACTGTGCTGTTTACTTATTATATGTAGCTCATACTTCATAGAAGCTGTTATTTTGCTTTTGAATA

>76913_76913_4_RPL5-CCDC18_RPL5_chr1_93300470_ENST00000370321_CCDC18_chr1_93657557_ENST00000401026_length(amino acids)=1265AA_BP=13
MSSSGRRSLFRRMGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAA
YAHELPKYGVKVGLTNYAAAYCTGLLLARRVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESK
EECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEK
LRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRS
LEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLS
SLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEM
TKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQ
QFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKF
EKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEE
KCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTE
TELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQR
AAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMES
VMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLE
ARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLT

--------------------------------------------------------------
>76913_76913_5_RPL5-CCDC18_RPL5_chr1_93303190_ENST00000370321_CCDC18_chr1_93687166_ENST00000338949_length(transcript)=2969nt_BP=795nt
CGCAAGGGCTGTGGCCCTTTTCCCACCCCCTAGCGCCGCTGGGCCTGCAGGTCTCTGTCGAGCAGCGGACGCCGGTCTCTGTTCCGCAGG
ATGGGGTTTGTTAAAGTTGTTAAGAATAAGGCCTACTTTAAGAGATACCAAGTGAAATTTAGAAGACGACGAGAGGGTAAAACTGATTAT
TATGCTCGGAAACGCTTGGTGATACAAGATAAAAATAAATACAACACACCCAAATACAGGATGATAGTTCGTGTGACAAACAGAGATATC
ATTTGTCAGATTGCTTATGCCCGTATAGAGGGGGATATGATAGTCTGCGCAGCGTATGCACACGAACTGCCAAAATATGGTGTGAAGGTT
GGCCTGACAAATTATGCTGCAGCATATTGTACTGGCCTGCTGCTGGCCCGCAGGCTTCTCAATAGGTTTGGCATGGACAAGATCTATGAA
GGCCAAGTGGAGGTGACTGGTGATGAATACAATGTGGAAAGCATTGATGGTCAGCCAGGTGCCTTCACCTGCTATTTGGATGCAGGCCTT
GCCAGAACTACCACTGGCAATAAAGTTTTTGGTGCCCTGAAGGGAGCTGTGGATGGAGGCTTGTCTATCCCTCACAGTACCAAACGATTC
CCTGGTTATGATTCTGAAAGCAAGGAATTTAATGCAGAAGTACATCGGAAGCACATCATGGGCCAGAATGTTGCAGATTACATGCGCTAC
TTAATGGAAGAAGATGAAGATGCTTACAAGAAACAGTTCTCTCAATACATAAAGAACAGCGTAACTCCAGACATGCTTGAAGCTCAACTA
GAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATCA
CTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTA
TCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGA
AATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTT
CAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAG
CTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTG
AGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAA
GTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCA
ATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTA
CAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAA
AGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCTC
ACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGG
GAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATTA
GAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGAA
CAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGATG
AAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTG
ACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCT
AGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGT
GAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGATG
ATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAG
GCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAAT
GAAGCATTACTTACTAAAGGAGAAAATGTGTAATTCAAAGAAGATACTGATGTGTTGAAAAAATGGAATTTTTGGTACTGTGCTGTTTAC
TTATTATATGTAGCTCATACTTCATAGAAGCTGTTATTTTGCTTTTGAATAAATTTTATATTTCAATATTTTAAAAGAAAGCCCTTCTAA

>76913_76913_5_RPL5-CCDC18_RPL5_chr1_93303190_ENST00000370321_CCDC18_chr1_93687166_ENST00000338949_length(amino acids)=892AA_BP=13
MSSSGRRSLFRRMGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAA
YAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVD
GGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNSVTPDMLEAQLEKKDQQFKEQEKTMSMLQ
QDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYC
LQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKR
QKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVL
ETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIRE
HRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQY
KEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAE

--------------------------------------------------------------
>76913_76913_6_RPL5-CCDC18_RPL5_chr1_93303190_ENST00000370321_CCDC18_chr1_93687166_ENST00000343253_length(transcript)=3201nt_BP=795nt
CGCAAGGGCTGTGGCCCTTTTCCCACCCCCTAGCGCCGCTGGGCCTGCAGGTCTCTGTCGAGCAGCGGACGCCGGTCTCTGTTCCGCAGG
ATGGGGTTTGTTAAAGTTGTTAAGAATAAGGCCTACTTTAAGAGATACCAAGTGAAATTTAGAAGACGACGAGAGGGTAAAACTGATTAT
TATGCTCGGAAACGCTTGGTGATACAAGATAAAAATAAATACAACACACCCAAATACAGGATGATAGTTCGTGTGACAAACAGAGATATC
ATTTGTCAGATTGCTTATGCCCGTATAGAGGGGGATATGATAGTCTGCGCAGCGTATGCACACGAACTGCCAAAATATGGTGTGAAGGTT
GGCCTGACAAATTATGCTGCAGCATATTGTACTGGCCTGCTGCTGGCCCGCAGGCTTCTCAATAGGTTTGGCATGGACAAGATCTATGAA
GGCCAAGTGGAGGTGACTGGTGATGAATACAATGTGGAAAGCATTGATGGTCAGCCAGGTGCCTTCACCTGCTATTTGGATGCAGGCCTT
GCCAGAACTACCACTGGCAATAAAGTTTTTGGTGCCCTGAAGGGAGCTGTGGATGGAGGCTTGTCTATCCCTCACAGTACCAAACGATTC
CCTGGTTATGATTCTGAAAGCAAGGAATTTAATGCAGAAGTACATCGGAAGCACATCATGGGCCAGAATGTTGCAGATTACATGCGCTAC
TTAATGGAAGAAGATGAAGATGCTTACAAGAAACAGTTCTCTCAATACATAAAGAACAGCGTAACTCCAGACATGCTTGAAGCTCAACTA
GAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATCA
CTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTA
TCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGA
AATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTT
CAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAG
CTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTG
AGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAA
GTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCA
ATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTA
CAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAA
AGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCTC
ACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGG
GAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATTA
GAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGAA
CAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGATG
AAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTG
ACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCT
AGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGT
GAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGATG
ATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAG
GCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAAT
GAAGCATTACTTACTAAAGAATCAGAATTAACCAGATTACAGGCCAAAATTTCTGGACATGAAAAGGCAGAAGACATCAAGTTTCTGCCA
GCCCCATTTACATCTCCAACAGAAATTATGCCTGATGTTCAAGATCCAAAATTTGCTAAATGTTTTCACACATCTTTTTCCAAGTGTACA
AAATTACGTCGCTCTATTAGTGCCAGTGATCTTACTTTCAAAATTCATGGTGATGAAGATCTTTCTGAAGAATTACTACAGGACTTAAAG
AAAATGCAATTAGAACAGCCTTCAACATTAGAAGAAAGCCATAAGAATCTGACTTACACCCAGCCAGACTCATTTAAACCTCTCACATAT
AACCTAGAAGCTGATAGTTCTGAGAATAATGACTTTAACACGCTTAGTGGGATGCTAAGATACATAAACAAAGAAGTAAGACTATTAAAA

>76913_76913_6_RPL5-CCDC18_RPL5_chr1_93303190_ENST00000370321_CCDC18_chr1_93687166_ENST00000343253_length(amino acids)=1048AA_BP=13
MSSSGRRSLFRRMGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAA
YAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVD
GGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNSVTPDMLEAQLEKKDQQFKEQEKTMSMLQ
QDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYC
LQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKR
QKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVL
ETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIRE
HRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQY
KEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAE
VESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKIS
GHEKAEDIKFLPAPFTSPTEIMPDVQDPKFAKCFHTSFSKCTKLRRSISASDLTFKIHGDEDLSEELLQDLKKMQLEQPSTLEESHKNLT

--------------------------------------------------------------
>76913_76913_7_RPL5-CCDC18_RPL5_chr1_93303190_ENST00000370321_CCDC18_chr1_93687166_ENST00000401026_length(transcript)=2863nt_BP=795nt
CGCAAGGGCTGTGGCCCTTTTCCCACCCCCTAGCGCCGCTGGGCCTGCAGGTCTCTGTCGAGCAGCGGACGCCGGTCTCTGTTCCGCAGG
ATGGGGTTTGTTAAAGTTGTTAAGAATAAGGCCTACTTTAAGAGATACCAAGTGAAATTTAGAAGACGACGAGAGGGTAAAACTGATTAT
TATGCTCGGAAACGCTTGGTGATACAAGATAAAAATAAATACAACACACCCAAATACAGGATGATAGTTCGTGTGACAAACAGAGATATC
ATTTGTCAGATTGCTTATGCCCGTATAGAGGGGGATATGATAGTCTGCGCAGCGTATGCACACGAACTGCCAAAATATGGTGTGAAGGTT
GGCCTGACAAATTATGCTGCAGCATATTGTACTGGCCTGCTGCTGGCCCGCAGGCTTCTCAATAGGTTTGGCATGGACAAGATCTATGAA
GGCCAAGTGGAGGTGACTGGTGATGAATACAATGTGGAAAGCATTGATGGTCAGCCAGGTGCCTTCACCTGCTATTTGGATGCAGGCCTT
GCCAGAACTACCACTGGCAATAAAGTTTTTGGTGCCCTGAAGGGAGCTGTGGATGGAGGCTTGTCTATCCCTCACAGTACCAAACGATTC
CCTGGTTATGATTCTGAAAGCAAGGAATTTAATGCAGAAGTACATCGGAAGCACATCATGGGCCAGAATGTTGCAGATTACATGCGCTAC
TTAATGGAAGAAGATGAAGATGCTTACAAGAAACAGTTCTCTCAATACATAAAGAACAGCGTAACTCCAGACATGCTTGAAGCTCAACTA
GAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATCA
CTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTA
TCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGA
AATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTT
CAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAG
CTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTG
AGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAA
GTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCA
ATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTA
CAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAA
AGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCTC
ACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGG
GAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATTA
GAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGAA
CAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGATG
AAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTG
ACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCT
AGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGT
GAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGATG
ATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAG
GCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAAT
GAAGCATTACTTACTAAAGGAGAAAATGTGTAATTCAAAGAAGATACTGATGTGTTGAAAAAATGGAATTTTTGGTACTGTGCTGTTTAC

>76913_76913_7_RPL5-CCDC18_RPL5_chr1_93303190_ENST00000370321_CCDC18_chr1_93687166_ENST00000401026_length(amino acids)=892AA_BP=13
MSSSGRRSLFRRMGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAA
YAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVD
GGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNSVTPDMLEAQLEKKDQQFKEQEKTMSMLQ
QDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYC
LQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKR
QKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVL
ETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIRE
HRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQY
KEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RPL5-CCDC18


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RPL5-CCDC18


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RPL5-CCDC18


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource