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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ATP11A-EXOC6B (FusionGDB2 ID:7713)

Fusion Gene Summary for ATP11A-EXOC6B

Fusion gene summary

Fusion gene information	Fusion gene name: ATP11A-EXOC6B
	Fusion gene ID: 7713
		Hgene	Tgene
	Gene symbol	ATP11A	EXOC6B
	Gene ID	23250	23233
	Gene name	ATPase phospholipid transporting 11A	exocyst complex component 6B
	Synonyms	ATPIH\|ATPIS	SEC15B\|SEC15L2\|SEMDJL3
	Cytomap	13q34	2p13.2
	Type of gene	protein-coding	protein-coding
	Description	probable phospholipid-transporting ATPase IHATPase, class VI, type 11AP4-ATPase flippase complex alpha subunit ATP11Aphospholipid-translocating ATPasepotential phospholipid-transporting ATPase IH	exocyst complex component 6BSEC15 homolog BSEC15-like protein 2exocyst complex component Sec15B
	Modification date	20200313	20200313
	UniProtAcc	P98196	Q9Y2D4
	Ensembl transtripts involved in fusion gene	ENST00000283558, ENST00000375630, ENST00000375645, ENST00000487903, ENST00000419448,	ENST00000410104, ENST00000490919, ENST00000272427,
Fusion gene scores	* DoF score	20 X 11 X 16=3520	10 X 8 X 6=480
	# samples	31	11
	** MAII score	log2(31/3520*10)=-3.50523530825042 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(11/480*10)=-2.12553088208386 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: ATP11A [Title/Abstract] AND EXOC6B [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ATP11A(113439571)-EXOC6B(72606999), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across ATP11A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across EXOC6B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	Non-Cancer	TCGA-HU-A4GP-11A	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-

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Fusion Gene ORF analysis for ATP11A-EXOC6B

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000283558	ENST00000410104	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
5CDS-intron	ENST00000283558	ENST00000490919	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
5CDS-intron	ENST00000375630	ENST00000410104	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
5CDS-intron	ENST00000375630	ENST00000490919	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
5CDS-intron	ENST00000375645	ENST00000410104	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
5CDS-intron	ENST00000375645	ENST00000490919	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
5CDS-intron	ENST00000487903	ENST00000410104	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
5CDS-intron	ENST00000487903	ENST00000490919	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
In-frame	ENST00000283558	ENST00000272427	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
In-frame	ENST00000375630	ENST00000272427	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
In-frame	ENST00000375645	ENST00000272427	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
In-frame	ENST00000487903	ENST00000272427	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
intron-3CDS	ENST00000419448	ENST00000272427	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
intron-intron	ENST00000419448	ENST00000410104	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-
intron-intron	ENST00000419448	ENST00000490919	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000283558	ATP11A	chr13	113439571	+	ENST00000272427	EXOC6B	chr2	72606999	-	4057	250	55	705	216
ENST00000375630	ATP11A	chr13	113439571	+	ENST00000272427	EXOC6B	chr2	72606999	-	4057	250	55	705	216
ENST00000487903	ATP11A	chr13	113439571	+	ENST00000272427	EXOC6B	chr2	72606999	-	4057	250	55	705	216
ENST00000375645	ATP11A	chr13	113439571	+	ENST00000272427	EXOC6B	chr2	72606999	-	4057	250	55	705	216

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000283558	ENST00000272427	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-	0.004912044	0.9950879
ENST00000375630	ENST00000272427	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-	0.004912044	0.9950879
ENST00000487903	ENST00000272427	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-	0.004912044	0.9950879
ENST00000375645	ENST00000272427	ATP11A	chr13	113439571	+	EXOC6B	chr2	72606999	-	0.004912044	0.9950879

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Fusion Genomic Features for ATP11A-EXOC6B

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ATP11A-EXOC6B

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:113439571/chr2:72606999)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ATP11A P98196	EXOC6B Q9Y2D4
FUNCTION: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of the plasma membrane (PubMed:25315773, PubMed:25947375, PubMed:26567335, PubMed:29799007, PubMed:30018401). Contributes to the maintenance of membrane lipid asymmetry with a specific role in morphogenesis of muscle cells. In myoblasts, mediates PS enrichment at the inner leaflet of plasma membrane, triggering PIEZO1-dependent Ca2+ influx and Rho GTPases signal transduction, subsequently leading to the assembly of cortical actomyosin fibers and myotube formation (PubMed:29799007). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib. {ECO:0000269\|PubMed:15860663, ECO:0000269\|PubMed:25315773, ECO:0000269\|PubMed:25947375, ECO:0000269\|PubMed:26567335, ECO:0000269\|PubMed:29799007, ECO:0000269\|PubMed:30018401, ECO:0000305}.	FUNCTION: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

1024_1029

1135.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

1051_1068

1135.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

1094_1134

1135.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

111_296

1135.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

1_61

1135.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

319_349

1135.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

373_881

1135.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

83_88

1135.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

903_914

1135.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

935_964

1135.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

987_1000

1135.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

1024_1029

2857.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

1051_1068

2857.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

1094_1134

2857.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

111_296

2857.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

1_61

2857.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

319_349

2857.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

373_881

2857.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

83_88

2857.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

903_914

2857.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

935_964

2857.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

987_1000

2857.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

1024_1029

2878.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

1051_1068

2878.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

1094_1134

2878.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

111_296

2878.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

1_61

2878.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

319_349

2878.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

373_881

2878.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

83_88

2878.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

903_914

2878.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

935_964

2878.0

Topological domain

Cytoplasmic

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

987_1000

2878.0

Topological domain

Extracellular

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

1001_1023

1135.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

1030_1050

1135.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

1069_1093

1135.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

297_318

1135.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

350_372

1135.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

62_82

1135.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

882_902

1135.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

89_110

1135.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

915_934

1135.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000283558

965_986

1135.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

1001_1023

2857.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

1030_1050

2857.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

1069_1093

2857.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

297_318

2857.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

350_372

2857.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

62_82

2857.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

882_902

2857.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

89_110

2857.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

915_934

2857.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000375645

965_986

2857.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

1001_1023

2878.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

1030_1050

2878.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

1069_1093

2878.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

297_318

2878.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

350_372

2878.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

62_82

2878.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

882_902

2878.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

89_110

2878.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

915_934

2878.0

Transmembrane

Helical

Hgene

ATP11A

chr13:113439571

chr2:72606999

ENST00000487903

965_986

2878.0

Transmembrane

Helical

Tgene

EXOC6B

chr13:113439571

chr2:72606999

ENST00000272427

50_119

660

812.0

Coiled coil

Ontology_term=ECO:0000255

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Fusion Gene Sequence for ATP11A-EXOC6B

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>7713_7713_1_ATP11A-EXOC6B_ATP11A_chr13_113439571_ENST00000283558_EXOC6B_chr2_72606999_ENST00000272427_length(transcript)=4057nt_BP=250nt
GCGGCCGCACTAGTACCCCGGAGCCCATGGGCGCGCCGAGCCGGGCGCGGGGGCGCTGAACGGCGGAGCGGGAGCGGCCGGAGGAGCCAT
GGACTGCAGCCTCGTGCGGACGCTCGTGCACAGATACTGTGCAGGAGAAGAGAATTGGGTGGACAGCAGGACCATCTACGTGGGACACAG
GGAGCCACCTCCGGGCGCAGAGGCCTACATCCCACAGAGATACCCAGACAACAGGATCGTCTCGTCCAAGGGAAAGGTGGCCCAGACAGC
GTGTATGTCAGCTTGCAAGCATTTAGCCACATCCTTGATGCAACTTTTGTTGGAAGCTGAAGTGCGGCAGCTCACCTTGGGAGCATTACA
GCAGTTCAACTTGGACGTCAGAGAATGTGAACAGTTTGCCAGATCCGGCCCGGTGCCTGGGTTCCAGGAGGACACGCTGCAGTTGGCCTT
CATCGACTTGAGACAACTTTTGGATCTTTTCATCCAGTGGGATTGGTCAACCTACCTTGCTGACTATGGTCAGCCCAACTGCAAGTACCT
CCGGGTAAACCCAGTGACTGCTCTGACCCTGCTTGAGAAGATGAAGGATACTAGCCGCAAGAACAACATGTTTGCACAGTTTCGGAAAAA
TGAGCGAGACAAGCAGAAACTCATTGACACCGTGGCCAAGCAGCTCCGAGGACTCATCAGCAGCCACCACTCATGAAGGGTGACCCCGGA
CCCACAGAGGCGACCTGCTGCAGCCTCTGTGTCAGTCTGGGGTCCAGCCCCAGCTGACCCTGCATTTGTGCATTCTTCTTCAAAGAGAGC
ATATGTATTTTTTTATTAACCCCTGTGCAGTATTCACATAACATTTCCCTATAGTAAAAGAGGCACAAGAATAAGCAAGTACATGAGATG
TTGCTAGGCTGGGACTCAGGGGAAGTTATTACTACACTATCTGTGTTATCTTAGAGATGGTGGTATCATCAATTCCACAGTGATGAACCA
CCTTTCATCCATGGCTCTAAAGCTTAGGTCTGGGGCTTAGGAACCATAAAAAGTGGGTATCTGGCGCTGGGAGGTAGAGTGAGTAAGCAA
AAGGATACTAAAATATGTCCTGTTCACTCTTGGATGCCCATTCACCACATAGATGAGGCTGATTCTTCTCAATACAAGGAAAGGGCATGG
CAAACATTACTATTTAGTACACTAAGGGCAGCTCTGGAGGGTCATCTCCTCAGTCTGCTGACTTTCACTGGCTTGTGAACAAGCATGGCA
TATGGCAAGATGACAGCTTCATTCCAATCCCCCAAGAATGGCGGTTTCTTTAGCCTGATCTAACCCCAGGCTTTTATTGCAATTTTTTCT
AGGGCAGGATACAGCTAAGTAGACAGCAGTAATAATTGGATCCCATGTTTAACTGCATATTGCCCCAGCTCTAGGAGTGTTGAGTCTCAA
CTCGAAGAGTTTTTCTGGATCTTGAAAGCCAGTTTTCATGGAATCAGAGACCCAATCCCTTCCCTGTTCATCTCATTTCCTTCACTTACA
GTCAGAGCACTTGGTTCAGGACATAAATCAACAGTTACTTCCATAGGCCTTCACAGGGCGTTTCAGACTTAGCCTCCTCCAGTAATGCCA
TTGAAATAGTTCAGATTTCGGAAGCCTAAAAATGGCCTTTACCTTACCCTTAGGTGTAACCTGAGGATTAGTTGGGATTGTTCCTTTATG
TTTTAAAACCAGCTTTTTGGTTATCATCTTTAAGGAAATGTCACCAGCTCTGCACTGTGGGGGCAGCCATGCCTGGACTGGATGCCTCTA
GGGATGGAGACATTGTTACCATAAAGTCGACAGAGCCAACCATGGCTTGTGGCTTGTTGCCTCTGGCCCAACTGTCCTTCACTAAATAAT
ATCCTAGATATTATTTTGTTGCTCAAGCCCAAGGTTCCCACCCTCTTTTGAGATCCCCAAAGCCATCTTTGGCCTTGTCTAAGAAAGATT
GCCTATAATCCTGTCCTCCAAACTCTAAAGCCTGGAGCAGCTTAGCGTGGAGGCTGCACTCATTGACCCAGATGGACTCCTGAGACTTAA
CGCAAGGGCTTTGCTATGAGGTCAGTCGGGGGAAACTGTACTTTAAGACACTTCAGAAAGATGCTACTGGCTAGTAGCAGAAAGATGGCT
AGTGGCAAGAGTATAATTGTGCATCACCAAACAATGACAAATAAGCCACACAGGCATTTCCAGCTTGGATTGATGGGAGGAGAGACTCAT
CAAACAGAATTCTTCACTACCTTTGTCAGCTACTGAGTTGCTTCTGGGGAGGGAAGTACTTCCTTGCCCCTCCCCAACCCCCCTACCTCA
CCATATCCTATCATATCTTGATAGTCATGGGGAAGAGGATGTGCACACAGACATACAAATTTCCTCAAAGCTGGAGAGACCAGGCTACAT
GTGAGCTCATAGATGCTGCTGAGGCTCATCCTGAGGGCTGGATGGTTGGCCAGGGTTTCAGAATGAGGGTAAGGGATGAGCACTGCCACC
CAGAACTTGATAAGCCAAGAGAAGGCAGGAGCCAAAATGGCATCGCCAAGCTCTCATCTTTGTTGAAACAAGTGAGAAACGATTATATTA
ATCTGAAGTTCTATTGCTTGAGAAGAGTTCAAAACACTTCTCTTTGCTAGTACCCAGTTTGCAGCAAGATCTCTTCAGCTTTAAGTGCTG
AGAGACTTTGAAGTGGAAATGGAGAGATGTGTAAGCATGGCACAGTGTTTGTCTTTTTAGAGGATCATCATTGCTGGTCTGGTCTCAAAC
CTCTGCCTTGGAAGAACTGTGCTATACAGGAAAAAGTGAACAAGGTGGAGGAATAGGGGTTATTCTGCACAGAAGTCCCATGAAAGGAAA
AGCTTATTCAAGCTCAAGACATAAAGATGGACCCTTTGATATATCTTCTCTCCATTCTTAGTCTGCCTTCACCTTATCTAACAAAAAACA
ACATGCAGCTACTGAGTTGTATGTAGAGACATACTCTTGGTGGGCCAGGGAAGGTAAAAACAGGGACCAGCAATGTCAAGTTTTTGAACT
AGAAAAGTGGGATGTTTTTAGTTTTGTCTATAACCTGTAGCTGGGCCAACCCTTGAGAGGACTTGTGCAAAGCATGTGTGCCCAGACCCA
TCAGACTCCTCAGATATGGCCTCAAATACCTAGAGATGTAGAAGTACCGTGGAGGGCCTCAATAAGAGGGCAAGCACACAGATGGCTAGA
AGCCTGTATGGCTTCTGGTCAGGATGAACCCTTGGCCAAGTTCTTGAGGAAACCAGGTCTATATTCCTGAAGGGACAGTTCAGTTTGGGA
CTCTATTAGGTTTCAGTAGTAATATAGGCTGCTTGCATCATTTTAACATTCATAGGGAAAATCTCTTTGAGCAGGCTATAAATGAAGCTG
TTGCAGGTAGGGAAGAACAGGACCTGAAAATGGGAACCAGGAAGTGAGATCCTGTTGGCAAAGGGAATGTAGAGCTTCCAGGGTGCATTG
CCCACTGTTCTCATTGCATACCAGTCCTCCAAGTCAGTCTAGCCTTACTGTACACTTGACAAGTGCTTACTCAGCAAGTCCCAGACCCAC
GGCCTTTTATCTCCCAAGACTGGCTTTGGCCATGACCTTCCTCATCAGGCCTCTGAGCACACTCTCTAGGAACTGCTGCAGAAATTCCCC
TACCTTAGCCTCCCTTCTCCCAGGACTCCTCTCTTGACTGCAATTGCCTCTTCTTCTTCTTCTTCTTCTTCCTTTTTGTTTTTTTTTTTT
TTGCCTGCATTCACAATTACTTTTCACAAAGGTGTTGGAAATGGCATTTTTATTTTACACAGATAGTTGCACATATATAGAGAAAATTAG
GAAAGTCCATTTTTAACTCTAAAGGGAACTTTTTTCTCTAAAACTTACTTGTAAAGCTACTGATACAGATGGGCCGCATGGTTAGGGGAA
AGCTCCTCTGTGAAAAGAGCATGTTTATTCCTCTTGTACATTTTCCTCTTTTAACTGCTATTAAACAAGAAAGCCTACATACCTGTTTCA

>7713_7713_1_ATP11A-EXOC6B_ATP11A_chr13_113439571_ENST00000283558_EXOC6B_chr2_72606999_ENST00000272427_length(amino acids)=216AA_BP=65
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKGKVAQTACMSACKHLATSLMQLLLE
AEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTS

--------------------------------------------------------------
>7713_7713_2_ATP11A-EXOC6B_ATP11A_chr13_113439571_ENST00000375630_EXOC6B_chr2_72606999_ENST00000272427_length(transcript)=4057nt_BP=250nt
GCGGCCGCACTAGTACCCCGGAGCCCATGGGCGCGCCGAGCCGGGCGCGGGGGCGCTGAACGGCGGAGCGGGAGCGGCCGGAGGAGCCAT
GGACTGCAGCCTCGTGCGGACGCTCGTGCACAGATACTGTGCAGGAGAAGAGAATTGGGTGGACAGCAGGACCATCTACGTGGGACACAG
GGAGCCACCTCCGGGCGCAGAGGCCTACATCCCACAGAGATACCCAGACAACAGGATCGTCTCGTCCAAGGGAAAGGTGGCCCAGACAGC
GTGTATGTCAGCTTGCAAGCATTTAGCCACATCCTTGATGCAACTTTTGTTGGAAGCTGAAGTGCGGCAGCTCACCTTGGGAGCATTACA
GCAGTTCAACTTGGACGTCAGAGAATGTGAACAGTTTGCCAGATCCGGCCCGGTGCCTGGGTTCCAGGAGGACACGCTGCAGTTGGCCTT
CATCGACTTGAGACAACTTTTGGATCTTTTCATCCAGTGGGATTGGTCAACCTACCTTGCTGACTATGGTCAGCCCAACTGCAAGTACCT
CCGGGTAAACCCAGTGACTGCTCTGACCCTGCTTGAGAAGATGAAGGATACTAGCCGCAAGAACAACATGTTTGCACAGTTTCGGAAAAA
TGAGCGAGACAAGCAGAAACTCATTGACACCGTGGCCAAGCAGCTCCGAGGACTCATCAGCAGCCACCACTCATGAAGGGTGACCCCGGA
CCCACAGAGGCGACCTGCTGCAGCCTCTGTGTCAGTCTGGGGTCCAGCCCCAGCTGACCCTGCATTTGTGCATTCTTCTTCAAAGAGAGC
ATATGTATTTTTTTATTAACCCCTGTGCAGTATTCACATAACATTTCCCTATAGTAAAAGAGGCACAAGAATAAGCAAGTACATGAGATG
TTGCTAGGCTGGGACTCAGGGGAAGTTATTACTACACTATCTGTGTTATCTTAGAGATGGTGGTATCATCAATTCCACAGTGATGAACCA
CCTTTCATCCATGGCTCTAAAGCTTAGGTCTGGGGCTTAGGAACCATAAAAAGTGGGTATCTGGCGCTGGGAGGTAGAGTGAGTAAGCAA
AAGGATACTAAAATATGTCCTGTTCACTCTTGGATGCCCATTCACCACATAGATGAGGCTGATTCTTCTCAATACAAGGAAAGGGCATGG
CAAACATTACTATTTAGTACACTAAGGGCAGCTCTGGAGGGTCATCTCCTCAGTCTGCTGACTTTCACTGGCTTGTGAACAAGCATGGCA
TATGGCAAGATGACAGCTTCATTCCAATCCCCCAAGAATGGCGGTTTCTTTAGCCTGATCTAACCCCAGGCTTTTATTGCAATTTTTTCT
AGGGCAGGATACAGCTAAGTAGACAGCAGTAATAATTGGATCCCATGTTTAACTGCATATTGCCCCAGCTCTAGGAGTGTTGAGTCTCAA
CTCGAAGAGTTTTTCTGGATCTTGAAAGCCAGTTTTCATGGAATCAGAGACCCAATCCCTTCCCTGTTCATCTCATTTCCTTCACTTACA
GTCAGAGCACTTGGTTCAGGACATAAATCAACAGTTACTTCCATAGGCCTTCACAGGGCGTTTCAGACTTAGCCTCCTCCAGTAATGCCA
TTGAAATAGTTCAGATTTCGGAAGCCTAAAAATGGCCTTTACCTTACCCTTAGGTGTAACCTGAGGATTAGTTGGGATTGTTCCTTTATG
TTTTAAAACCAGCTTTTTGGTTATCATCTTTAAGGAAATGTCACCAGCTCTGCACTGTGGGGGCAGCCATGCCTGGACTGGATGCCTCTA
GGGATGGAGACATTGTTACCATAAAGTCGACAGAGCCAACCATGGCTTGTGGCTTGTTGCCTCTGGCCCAACTGTCCTTCACTAAATAAT
ATCCTAGATATTATTTTGTTGCTCAAGCCCAAGGTTCCCACCCTCTTTTGAGATCCCCAAAGCCATCTTTGGCCTTGTCTAAGAAAGATT
GCCTATAATCCTGTCCTCCAAACTCTAAAGCCTGGAGCAGCTTAGCGTGGAGGCTGCACTCATTGACCCAGATGGACTCCTGAGACTTAA
CGCAAGGGCTTTGCTATGAGGTCAGTCGGGGGAAACTGTACTTTAAGACACTTCAGAAAGATGCTACTGGCTAGTAGCAGAAAGATGGCT
AGTGGCAAGAGTATAATTGTGCATCACCAAACAATGACAAATAAGCCACACAGGCATTTCCAGCTTGGATTGATGGGAGGAGAGACTCAT
CAAACAGAATTCTTCACTACCTTTGTCAGCTACTGAGTTGCTTCTGGGGAGGGAAGTACTTCCTTGCCCCTCCCCAACCCCCCTACCTCA
CCATATCCTATCATATCTTGATAGTCATGGGGAAGAGGATGTGCACACAGACATACAAATTTCCTCAAAGCTGGAGAGACCAGGCTACAT
GTGAGCTCATAGATGCTGCTGAGGCTCATCCTGAGGGCTGGATGGTTGGCCAGGGTTTCAGAATGAGGGTAAGGGATGAGCACTGCCACC
CAGAACTTGATAAGCCAAGAGAAGGCAGGAGCCAAAATGGCATCGCCAAGCTCTCATCTTTGTTGAAACAAGTGAGAAACGATTATATTA
ATCTGAAGTTCTATTGCTTGAGAAGAGTTCAAAACACTTCTCTTTGCTAGTACCCAGTTTGCAGCAAGATCTCTTCAGCTTTAAGTGCTG
AGAGACTTTGAAGTGGAAATGGAGAGATGTGTAAGCATGGCACAGTGTTTGTCTTTTTAGAGGATCATCATTGCTGGTCTGGTCTCAAAC
CTCTGCCTTGGAAGAACTGTGCTATACAGGAAAAAGTGAACAAGGTGGAGGAATAGGGGTTATTCTGCACAGAAGTCCCATGAAAGGAAA
AGCTTATTCAAGCTCAAGACATAAAGATGGACCCTTTGATATATCTTCTCTCCATTCTTAGTCTGCCTTCACCTTATCTAACAAAAAACA
ACATGCAGCTACTGAGTTGTATGTAGAGACATACTCTTGGTGGGCCAGGGAAGGTAAAAACAGGGACCAGCAATGTCAAGTTTTTGAACT
AGAAAAGTGGGATGTTTTTAGTTTTGTCTATAACCTGTAGCTGGGCCAACCCTTGAGAGGACTTGTGCAAAGCATGTGTGCCCAGACCCA
TCAGACTCCTCAGATATGGCCTCAAATACCTAGAGATGTAGAAGTACCGTGGAGGGCCTCAATAAGAGGGCAAGCACACAGATGGCTAGA
AGCCTGTATGGCTTCTGGTCAGGATGAACCCTTGGCCAAGTTCTTGAGGAAACCAGGTCTATATTCCTGAAGGGACAGTTCAGTTTGGGA
CTCTATTAGGTTTCAGTAGTAATATAGGCTGCTTGCATCATTTTAACATTCATAGGGAAAATCTCTTTGAGCAGGCTATAAATGAAGCTG
TTGCAGGTAGGGAAGAACAGGACCTGAAAATGGGAACCAGGAAGTGAGATCCTGTTGGCAAAGGGAATGTAGAGCTTCCAGGGTGCATTG
CCCACTGTTCTCATTGCATACCAGTCCTCCAAGTCAGTCTAGCCTTACTGTACACTTGACAAGTGCTTACTCAGCAAGTCCCAGACCCAC
GGCCTTTTATCTCCCAAGACTGGCTTTGGCCATGACCTTCCTCATCAGGCCTCTGAGCACACTCTCTAGGAACTGCTGCAGAAATTCCCC
TACCTTAGCCTCCCTTCTCCCAGGACTCCTCTCTTGACTGCAATTGCCTCTTCTTCTTCTTCTTCTTCTTCCTTTTTGTTTTTTTTTTTT
TTGCCTGCATTCACAATTACTTTTCACAAAGGTGTTGGAAATGGCATTTTTATTTTACACAGATAGTTGCACATATATAGAGAAAATTAG
GAAAGTCCATTTTTAACTCTAAAGGGAACTTTTTTCTCTAAAACTTACTTGTAAAGCTACTGATACAGATGGGCCGCATGGTTAGGGGAA
AGCTCCTCTGTGAAAAGAGCATGTTTATTCCTCTTGTACATTTTCCTCTTTTAACTGCTATTAAACAAGAAAGCCTACATACCTGTTTCA

>7713_7713_2_ATP11A-EXOC6B_ATP11A_chr13_113439571_ENST00000375630_EXOC6B_chr2_72606999_ENST00000272427_length(amino acids)=216AA_BP=65
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKGKVAQTACMSACKHLATSLMQLLLE
AEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTS

--------------------------------------------------------------
>7713_7713_3_ATP11A-EXOC6B_ATP11A_chr13_113439571_ENST00000375645_EXOC6B_chr2_72606999_ENST00000272427_length(transcript)=4057nt_BP=250nt
GCGGCCGCACTAGTACCCCGGAGCCCATGGGCGCGCCGAGCCGGGCGCGGGGGCGCTGAACGGCGGAGCGGGAGCGGCCGGAGGAGCCAT
GGACTGCAGCCTCGTGCGGACGCTCGTGCACAGATACTGTGCAGGAGAAGAGAATTGGGTGGACAGCAGGACCATCTACGTGGGACACAG
GGAGCCACCTCCGGGCGCAGAGGCCTACATCCCACAGAGATACCCAGACAACAGGATCGTCTCGTCCAAGGGAAAGGTGGCCCAGACAGC
GTGTATGTCAGCTTGCAAGCATTTAGCCACATCCTTGATGCAACTTTTGTTGGAAGCTGAAGTGCGGCAGCTCACCTTGGGAGCATTACA
GCAGTTCAACTTGGACGTCAGAGAATGTGAACAGTTTGCCAGATCCGGCCCGGTGCCTGGGTTCCAGGAGGACACGCTGCAGTTGGCCTT
CATCGACTTGAGACAACTTTTGGATCTTTTCATCCAGTGGGATTGGTCAACCTACCTTGCTGACTATGGTCAGCCCAACTGCAAGTACCT
CCGGGTAAACCCAGTGACTGCTCTGACCCTGCTTGAGAAGATGAAGGATACTAGCCGCAAGAACAACATGTTTGCACAGTTTCGGAAAAA
TGAGCGAGACAAGCAGAAACTCATTGACACCGTGGCCAAGCAGCTCCGAGGACTCATCAGCAGCCACCACTCATGAAGGGTGACCCCGGA
CCCACAGAGGCGACCTGCTGCAGCCTCTGTGTCAGTCTGGGGTCCAGCCCCAGCTGACCCTGCATTTGTGCATTCTTCTTCAAAGAGAGC
ATATGTATTTTTTTATTAACCCCTGTGCAGTATTCACATAACATTTCCCTATAGTAAAAGAGGCACAAGAATAAGCAAGTACATGAGATG
TTGCTAGGCTGGGACTCAGGGGAAGTTATTACTACACTATCTGTGTTATCTTAGAGATGGTGGTATCATCAATTCCACAGTGATGAACCA
CCTTTCATCCATGGCTCTAAAGCTTAGGTCTGGGGCTTAGGAACCATAAAAAGTGGGTATCTGGCGCTGGGAGGTAGAGTGAGTAAGCAA
AAGGATACTAAAATATGTCCTGTTCACTCTTGGATGCCCATTCACCACATAGATGAGGCTGATTCTTCTCAATACAAGGAAAGGGCATGG
CAAACATTACTATTTAGTACACTAAGGGCAGCTCTGGAGGGTCATCTCCTCAGTCTGCTGACTTTCACTGGCTTGTGAACAAGCATGGCA
TATGGCAAGATGACAGCTTCATTCCAATCCCCCAAGAATGGCGGTTTCTTTAGCCTGATCTAACCCCAGGCTTTTATTGCAATTTTTTCT
AGGGCAGGATACAGCTAAGTAGACAGCAGTAATAATTGGATCCCATGTTTAACTGCATATTGCCCCAGCTCTAGGAGTGTTGAGTCTCAA
CTCGAAGAGTTTTTCTGGATCTTGAAAGCCAGTTTTCATGGAATCAGAGACCCAATCCCTTCCCTGTTCATCTCATTTCCTTCACTTACA
GTCAGAGCACTTGGTTCAGGACATAAATCAACAGTTACTTCCATAGGCCTTCACAGGGCGTTTCAGACTTAGCCTCCTCCAGTAATGCCA
TTGAAATAGTTCAGATTTCGGAAGCCTAAAAATGGCCTTTACCTTACCCTTAGGTGTAACCTGAGGATTAGTTGGGATTGTTCCTTTATG
TTTTAAAACCAGCTTTTTGGTTATCATCTTTAAGGAAATGTCACCAGCTCTGCACTGTGGGGGCAGCCATGCCTGGACTGGATGCCTCTA
GGGATGGAGACATTGTTACCATAAAGTCGACAGAGCCAACCATGGCTTGTGGCTTGTTGCCTCTGGCCCAACTGTCCTTCACTAAATAAT
ATCCTAGATATTATTTTGTTGCTCAAGCCCAAGGTTCCCACCCTCTTTTGAGATCCCCAAAGCCATCTTTGGCCTTGTCTAAGAAAGATT
GCCTATAATCCTGTCCTCCAAACTCTAAAGCCTGGAGCAGCTTAGCGTGGAGGCTGCACTCATTGACCCAGATGGACTCCTGAGACTTAA
CGCAAGGGCTTTGCTATGAGGTCAGTCGGGGGAAACTGTACTTTAAGACACTTCAGAAAGATGCTACTGGCTAGTAGCAGAAAGATGGCT
AGTGGCAAGAGTATAATTGTGCATCACCAAACAATGACAAATAAGCCACACAGGCATTTCCAGCTTGGATTGATGGGAGGAGAGACTCAT
CAAACAGAATTCTTCACTACCTTTGTCAGCTACTGAGTTGCTTCTGGGGAGGGAAGTACTTCCTTGCCCCTCCCCAACCCCCCTACCTCA
CCATATCCTATCATATCTTGATAGTCATGGGGAAGAGGATGTGCACACAGACATACAAATTTCCTCAAAGCTGGAGAGACCAGGCTACAT
GTGAGCTCATAGATGCTGCTGAGGCTCATCCTGAGGGCTGGATGGTTGGCCAGGGTTTCAGAATGAGGGTAAGGGATGAGCACTGCCACC
CAGAACTTGATAAGCCAAGAGAAGGCAGGAGCCAAAATGGCATCGCCAAGCTCTCATCTTTGTTGAAACAAGTGAGAAACGATTATATTA
ATCTGAAGTTCTATTGCTTGAGAAGAGTTCAAAACACTTCTCTTTGCTAGTACCCAGTTTGCAGCAAGATCTCTTCAGCTTTAAGTGCTG
AGAGACTTTGAAGTGGAAATGGAGAGATGTGTAAGCATGGCACAGTGTTTGTCTTTTTAGAGGATCATCATTGCTGGTCTGGTCTCAAAC
CTCTGCCTTGGAAGAACTGTGCTATACAGGAAAAAGTGAACAAGGTGGAGGAATAGGGGTTATTCTGCACAGAAGTCCCATGAAAGGAAA
AGCTTATTCAAGCTCAAGACATAAAGATGGACCCTTTGATATATCTTCTCTCCATTCTTAGTCTGCCTTCACCTTATCTAACAAAAAACA
ACATGCAGCTACTGAGTTGTATGTAGAGACATACTCTTGGTGGGCCAGGGAAGGTAAAAACAGGGACCAGCAATGTCAAGTTTTTGAACT
AGAAAAGTGGGATGTTTTTAGTTTTGTCTATAACCTGTAGCTGGGCCAACCCTTGAGAGGACTTGTGCAAAGCATGTGTGCCCAGACCCA
TCAGACTCCTCAGATATGGCCTCAAATACCTAGAGATGTAGAAGTACCGTGGAGGGCCTCAATAAGAGGGCAAGCACACAGATGGCTAGA
AGCCTGTATGGCTTCTGGTCAGGATGAACCCTTGGCCAAGTTCTTGAGGAAACCAGGTCTATATTCCTGAAGGGACAGTTCAGTTTGGGA
CTCTATTAGGTTTCAGTAGTAATATAGGCTGCTTGCATCATTTTAACATTCATAGGGAAAATCTCTTTGAGCAGGCTATAAATGAAGCTG
TTGCAGGTAGGGAAGAACAGGACCTGAAAATGGGAACCAGGAAGTGAGATCCTGTTGGCAAAGGGAATGTAGAGCTTCCAGGGTGCATTG
CCCACTGTTCTCATTGCATACCAGTCCTCCAAGTCAGTCTAGCCTTACTGTACACTTGACAAGTGCTTACTCAGCAAGTCCCAGACCCAC
GGCCTTTTATCTCCCAAGACTGGCTTTGGCCATGACCTTCCTCATCAGGCCTCTGAGCACACTCTCTAGGAACTGCTGCAGAAATTCCCC
TACCTTAGCCTCCCTTCTCCCAGGACTCCTCTCTTGACTGCAATTGCCTCTTCTTCTTCTTCTTCTTCTTCCTTTTTGTTTTTTTTTTTT
TTGCCTGCATTCACAATTACTTTTCACAAAGGTGTTGGAAATGGCATTTTTATTTTACACAGATAGTTGCACATATATAGAGAAAATTAG
GAAAGTCCATTTTTAACTCTAAAGGGAACTTTTTTCTCTAAAACTTACTTGTAAAGCTACTGATACAGATGGGCCGCATGGTTAGGGGAA
AGCTCCTCTGTGAAAAGAGCATGTTTATTCCTCTTGTACATTTTCCTCTTTTAACTGCTATTAAACAAGAAAGCCTACATACCTGTTTCA

>7713_7713_3_ATP11A-EXOC6B_ATP11A_chr13_113439571_ENST00000375645_EXOC6B_chr2_72606999_ENST00000272427_length(amino acids)=216AA_BP=65
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKGKVAQTACMSACKHLATSLMQLLLE
AEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTS

--------------------------------------------------------------
>7713_7713_4_ATP11A-EXOC6B_ATP11A_chr13_113439571_ENST00000487903_EXOC6B_chr2_72606999_ENST00000272427_length(transcript)=4057nt_BP=250nt
GCGGCCGCACTAGTACCCCGGAGCCCATGGGCGCGCCGAGCCGGGCGCGGGGGCGCTGAACGGCGGAGCGGGAGCGGCCGGAGGAGCCAT
GGACTGCAGCCTCGTGCGGACGCTCGTGCACAGATACTGTGCAGGAGAAGAGAATTGGGTGGACAGCAGGACCATCTACGTGGGACACAG
GGAGCCACCTCCGGGCGCAGAGGCCTACATCCCACAGAGATACCCAGACAACAGGATCGTCTCGTCCAAGGGAAAGGTGGCCCAGACAGC
GTGTATGTCAGCTTGCAAGCATTTAGCCACATCCTTGATGCAACTTTTGTTGGAAGCTGAAGTGCGGCAGCTCACCTTGGGAGCATTACA
GCAGTTCAACTTGGACGTCAGAGAATGTGAACAGTTTGCCAGATCCGGCCCGGTGCCTGGGTTCCAGGAGGACACGCTGCAGTTGGCCTT
CATCGACTTGAGACAACTTTTGGATCTTTTCATCCAGTGGGATTGGTCAACCTACCTTGCTGACTATGGTCAGCCCAACTGCAAGTACCT
CCGGGTAAACCCAGTGACTGCTCTGACCCTGCTTGAGAAGATGAAGGATACTAGCCGCAAGAACAACATGTTTGCACAGTTTCGGAAAAA
TGAGCGAGACAAGCAGAAACTCATTGACACCGTGGCCAAGCAGCTCCGAGGACTCATCAGCAGCCACCACTCATGAAGGGTGACCCCGGA
CCCACAGAGGCGACCTGCTGCAGCCTCTGTGTCAGTCTGGGGTCCAGCCCCAGCTGACCCTGCATTTGTGCATTCTTCTTCAAAGAGAGC
ATATGTATTTTTTTATTAACCCCTGTGCAGTATTCACATAACATTTCCCTATAGTAAAAGAGGCACAAGAATAAGCAAGTACATGAGATG
TTGCTAGGCTGGGACTCAGGGGAAGTTATTACTACACTATCTGTGTTATCTTAGAGATGGTGGTATCATCAATTCCACAGTGATGAACCA
CCTTTCATCCATGGCTCTAAAGCTTAGGTCTGGGGCTTAGGAACCATAAAAAGTGGGTATCTGGCGCTGGGAGGTAGAGTGAGTAAGCAA
AAGGATACTAAAATATGTCCTGTTCACTCTTGGATGCCCATTCACCACATAGATGAGGCTGATTCTTCTCAATACAAGGAAAGGGCATGG
CAAACATTACTATTTAGTACACTAAGGGCAGCTCTGGAGGGTCATCTCCTCAGTCTGCTGACTTTCACTGGCTTGTGAACAAGCATGGCA
TATGGCAAGATGACAGCTTCATTCCAATCCCCCAAGAATGGCGGTTTCTTTAGCCTGATCTAACCCCAGGCTTTTATTGCAATTTTTTCT
AGGGCAGGATACAGCTAAGTAGACAGCAGTAATAATTGGATCCCATGTTTAACTGCATATTGCCCCAGCTCTAGGAGTGTTGAGTCTCAA
CTCGAAGAGTTTTTCTGGATCTTGAAAGCCAGTTTTCATGGAATCAGAGACCCAATCCCTTCCCTGTTCATCTCATTTCCTTCACTTACA
GTCAGAGCACTTGGTTCAGGACATAAATCAACAGTTACTTCCATAGGCCTTCACAGGGCGTTTCAGACTTAGCCTCCTCCAGTAATGCCA
TTGAAATAGTTCAGATTTCGGAAGCCTAAAAATGGCCTTTACCTTACCCTTAGGTGTAACCTGAGGATTAGTTGGGATTGTTCCTTTATG
TTTTAAAACCAGCTTTTTGGTTATCATCTTTAAGGAAATGTCACCAGCTCTGCACTGTGGGGGCAGCCATGCCTGGACTGGATGCCTCTA
GGGATGGAGACATTGTTACCATAAAGTCGACAGAGCCAACCATGGCTTGTGGCTTGTTGCCTCTGGCCCAACTGTCCTTCACTAAATAAT
ATCCTAGATATTATTTTGTTGCTCAAGCCCAAGGTTCCCACCCTCTTTTGAGATCCCCAAAGCCATCTTTGGCCTTGTCTAAGAAAGATT
GCCTATAATCCTGTCCTCCAAACTCTAAAGCCTGGAGCAGCTTAGCGTGGAGGCTGCACTCATTGACCCAGATGGACTCCTGAGACTTAA
CGCAAGGGCTTTGCTATGAGGTCAGTCGGGGGAAACTGTACTTTAAGACACTTCAGAAAGATGCTACTGGCTAGTAGCAGAAAGATGGCT
AGTGGCAAGAGTATAATTGTGCATCACCAAACAATGACAAATAAGCCACACAGGCATTTCCAGCTTGGATTGATGGGAGGAGAGACTCAT
CAAACAGAATTCTTCACTACCTTTGTCAGCTACTGAGTTGCTTCTGGGGAGGGAAGTACTTCCTTGCCCCTCCCCAACCCCCCTACCTCA
CCATATCCTATCATATCTTGATAGTCATGGGGAAGAGGATGTGCACACAGACATACAAATTTCCTCAAAGCTGGAGAGACCAGGCTACAT
GTGAGCTCATAGATGCTGCTGAGGCTCATCCTGAGGGCTGGATGGTTGGCCAGGGTTTCAGAATGAGGGTAAGGGATGAGCACTGCCACC
CAGAACTTGATAAGCCAAGAGAAGGCAGGAGCCAAAATGGCATCGCCAAGCTCTCATCTTTGTTGAAACAAGTGAGAAACGATTATATTA
ATCTGAAGTTCTATTGCTTGAGAAGAGTTCAAAACACTTCTCTTTGCTAGTACCCAGTTTGCAGCAAGATCTCTTCAGCTTTAAGTGCTG
AGAGACTTTGAAGTGGAAATGGAGAGATGTGTAAGCATGGCACAGTGTTTGTCTTTTTAGAGGATCATCATTGCTGGTCTGGTCTCAAAC
CTCTGCCTTGGAAGAACTGTGCTATACAGGAAAAAGTGAACAAGGTGGAGGAATAGGGGTTATTCTGCACAGAAGTCCCATGAAAGGAAA
AGCTTATTCAAGCTCAAGACATAAAGATGGACCCTTTGATATATCTTCTCTCCATTCTTAGTCTGCCTTCACCTTATCTAACAAAAAACA
ACATGCAGCTACTGAGTTGTATGTAGAGACATACTCTTGGTGGGCCAGGGAAGGTAAAAACAGGGACCAGCAATGTCAAGTTTTTGAACT
AGAAAAGTGGGATGTTTTTAGTTTTGTCTATAACCTGTAGCTGGGCCAACCCTTGAGAGGACTTGTGCAAAGCATGTGTGCCCAGACCCA
TCAGACTCCTCAGATATGGCCTCAAATACCTAGAGATGTAGAAGTACCGTGGAGGGCCTCAATAAGAGGGCAAGCACACAGATGGCTAGA
AGCCTGTATGGCTTCTGGTCAGGATGAACCCTTGGCCAAGTTCTTGAGGAAACCAGGTCTATATTCCTGAAGGGACAGTTCAGTTTGGGA
CTCTATTAGGTTTCAGTAGTAATATAGGCTGCTTGCATCATTTTAACATTCATAGGGAAAATCTCTTTGAGCAGGCTATAAATGAAGCTG
TTGCAGGTAGGGAAGAACAGGACCTGAAAATGGGAACCAGGAAGTGAGATCCTGTTGGCAAAGGGAATGTAGAGCTTCCAGGGTGCATTG
CCCACTGTTCTCATTGCATACCAGTCCTCCAAGTCAGTCTAGCCTTACTGTACACTTGACAAGTGCTTACTCAGCAAGTCCCAGACCCAC
GGCCTTTTATCTCCCAAGACTGGCTTTGGCCATGACCTTCCTCATCAGGCCTCTGAGCACACTCTCTAGGAACTGCTGCAGAAATTCCCC
TACCTTAGCCTCCCTTCTCCCAGGACTCCTCTCTTGACTGCAATTGCCTCTTCTTCTTCTTCTTCTTCTTCCTTTTTGTTTTTTTTTTTT
TTGCCTGCATTCACAATTACTTTTCACAAAGGTGTTGGAAATGGCATTTTTATTTTACACAGATAGTTGCACATATATAGAGAAAATTAG
GAAAGTCCATTTTTAACTCTAAAGGGAACTTTTTTCTCTAAAACTTACTTGTAAAGCTACTGATACAGATGGGCCGCATGGTTAGGGGAA
AGCTCCTCTGTGAAAAGAGCATGTTTATTCCTCTTGTACATTTTCCTCTTTTAACTGCTATTAAACAAGAAAGCCTACATACCTGTTTCA

>7713_7713_4_ATP11A-EXOC6B_ATP11A_chr13_113439571_ENST00000487903_EXOC6B_chr2_72606999_ENST00000272427_length(amino acids)=216AA_BP=65
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKGKVAQTACMSACKHLATSLMQLLLE
AEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ATP11A-EXOC6B

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for ATP11A-EXOC6B

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for ATP11A-EXOC6B

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source