FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:RPRD1A-RALGAPA2 (FusionGDB2 ID:77240)

Fusion Gene Summary for RPRD1A-RALGAPA2

check button Fusion gene summary
Fusion gene informationFusion gene name: RPRD1A-RALGAPA2
Fusion gene ID: 77240
HgeneTgene
Gene symbol

RPRD1A

RALGAPA2

Gene ID

55197

57186

Gene nameregulation of nuclear pre-mRNA domain containing 1ARal GTPase activating protein catalytic subunit alpha 2
SynonymsHsT3101|P15RSAS250|C20orf74|bA287B20.1|dJ1049G11|dJ1049G11.4|p220
Cytomap

18q12.2

20p11.23

Type of geneprotein-codingprotein-coding
Descriptionregulation of nuclear pre-mRNA domain-containing protein 1ACDKN2B-related proteinCyclin-dependent kinase inhibitor 2B-related protein (p15INK4B-related protein)cyclin-dependent kinase 2B-inhibitor-related proteinp15INK4B-related proteinral GTPase-activating protein subunit alpha-2250 kDa substrate of AktRal GTPase activating protein catalytic alpha subunit 2Ral GTPase activating protein, alpha subunit 2 (catalytic)RapGAPalpha2akt substrate AS250ral GTPase-activating protein alpha
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000319040, ENST00000337059, 
ENST00000357384, ENST00000399022, 
ENST00000588737, ENST00000590898, 
ENST00000588459, 		ENST00000495793, 
ENST00000202677, 
Fusion gene scores* DoF score13 X 14 X 7=127413 X 13 X 6=1014
# samples 1715
** MAII scorelog2(17/1274*10)=-2.9057586261186
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1014*10)=-2.75702324650746
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RPRD1A [Title/Abstract] AND RALGAPA2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRPRD1A(33610771)-RALGAPA2(20661445), # samples:3
Anticipated loss of major functional domain due to fusion event.RPRD1A-RALGAPA2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across RPRD1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RALGAPA2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AO-A12F-01ARPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
ChimerDB4BRCATCGA-AO-A12FRPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-


Top

Fusion Gene ORF analysis for RPRD1A-RALGAPA2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000319040ENST00000495793RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
5CDS-intronENST00000319040ENST00000495793RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
5CDS-intronENST00000337059ENST00000495793RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
5CDS-intronENST00000337059ENST00000495793RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
5CDS-intronENST00000357384ENST00000495793RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
5CDS-intronENST00000357384ENST00000495793RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
5CDS-intronENST00000399022ENST00000495793RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
5CDS-intronENST00000399022ENST00000495793RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
5CDS-intronENST00000588737ENST00000495793RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
5CDS-intronENST00000588737ENST00000495793RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
5CDS-intronENST00000590898ENST00000495793RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
5CDS-intronENST00000590898ENST00000495793RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
Frame-shiftENST00000337059ENST00000202677RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
Frame-shiftENST00000337059ENST00000202677RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
Frame-shiftENST00000357384ENST00000202677RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
Frame-shiftENST00000357384ENST00000202677RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
Frame-shiftENST00000590898ENST00000202677RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
Frame-shiftENST00000590898ENST00000202677RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
In-frameENST00000319040ENST00000202677RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
In-frameENST00000319040ENST00000202677RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
In-frameENST00000399022ENST00000202677RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
In-frameENST00000399022ENST00000202677RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
In-frameENST00000588737ENST00000202677RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
In-frameENST00000588737ENST00000202677RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
intron-3CDSENST00000588459ENST00000202677RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
intron-3CDSENST00000588459ENST00000202677RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-
intron-intronENST00000588459ENST00000495793RPRD1Achr18

33610771

-RALGAPA2chr20

20661445

-
intron-intronENST00000588459ENST00000495793RPRD1Achr18

33610770

-RALGAPA2chr20

20661445

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000399022RPRD1Achr1833610771-ENST00000202677RALGAPA2chr2020661445-669665874461731809
ENST00000588737RPRD1Achr1833610771-ENST00000202677RALGAPA2chr2020661445-673870078662151809
ENST00000319040RPRD1Achr1833610771-ENST00000202677RALGAPA2chr2020661445-667663872461531809
ENST00000399022RPRD1Achr1833610770-ENST00000202677RALGAPA2chr2020661445-669665874461731809
ENST00000588737RPRD1Achr1833610770-ENST00000202677RALGAPA2chr2020661445-673870078662151809
ENST00000319040RPRD1Achr1833610770-ENST00000202677RALGAPA2chr2020661445-667663872461531809

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000399022ENST00000202677RPRD1Achr1833610771-RALGAPA2chr2020661445-0.0014072450.9985928
ENST00000588737ENST00000202677RPRD1Achr1833610771-RALGAPA2chr2020661445-0.0013608970.99863905
ENST00000319040ENST00000202677RPRD1Achr1833610771-RALGAPA2chr2020661445-0.0013471180.9986528
ENST00000399022ENST00000202677RPRD1Achr1833610770-RALGAPA2chr2020661445-0.0014072450.9985928
ENST00000588737ENST00000202677RPRD1Achr1833610770-RALGAPA2chr2020661445-0.0013608970.99863905
ENST00000319040ENST00000202677RPRD1Achr1833610770-RALGAPA2chr2020661445-0.0013471180.9986528

Top

Fusion Genomic Features for RPRD1A-RALGAPA2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for RPRD1A-RALGAPA2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:33610771/chr20:20661445)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000319040-472_133162290.0DomainCID
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000357384-482_133162471.6666666666667DomainCID
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000399022-472_133162313.0DomainCID
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000319040-472_133162290.0DomainCID
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000357384-482_133162471.6666666666667DomainCID
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000399022-472_133162313.0DomainCID
TgeneRALGAPA2chr18:33610770chr20:20661445ENST00000202677040757_760351974.6666666666667Compositional biasNote=Poly-Gln
TgeneRALGAPA2chr18:33610770chr20:20661445ENST00000202677040790_793351974.6666666666667Compositional biasNote=Poly-Ser
TgeneRALGAPA2chr18:33610771chr20:20661445ENST00000202677040757_760351974.6666666666667Compositional biasNote=Poly-Gln
TgeneRALGAPA2chr18:33610771chr20:20661445ENST00000202677040790_793351974.6666666666667Compositional biasNote=Poly-Ser
TgeneRALGAPA2chr18:33610770chr20:20661445ENST000002026770401635_1843351974.6666666666667DomainRap-GAP
TgeneRALGAPA2chr18:33610771chr20:20661445ENST000002026770401635_1843351974.6666666666667DomainRap-GAP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000319040-47244_286162290.0Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000337059-48244_286126522.3333333333334Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000357384-48244_286162471.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000399022-47244_286162313.0Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000588737-58244_286126277.0Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000590898-59244_286126488.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000319040-47244_286162290.0Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000337059-48244_286126522.3333333333334Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000357384-48244_286162471.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000399022-47244_286162313.0Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000588737-58244_286126277.0Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000590898-59244_286126488.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000337059-482_133126522.3333333333334DomainCID
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000588737-582_133126277.0DomainCID
HgeneRPRD1Achr18:33610770chr20:20661445ENST00000590898-592_133126488.6666666666667DomainCID
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000337059-482_133126522.3333333333334DomainCID
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000588737-582_133126277.0DomainCID
HgeneRPRD1Achr18:33610771chr20:20661445ENST00000590898-592_133126488.6666666666667DomainCID


Top

Fusion Gene Sequence for RPRD1A-RALGAPA2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>77240_77240_1_RPRD1A-RALGAPA2_RPRD1A_chr18_33610770_ENST00000319040_RALGAPA2_chr20_20661445_ENST00000202677_length(transcript)=6676nt_BP=638nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGCCAAACCAAACAGGAAGCTTACTTTTCTCTACCTAGCCAATGATGTCATACAGAACA
GCAAGAGGAAGGGGCCAGAGTTTACAAAAGATTTTGCACCAGTTATAGTGGAGGCTTTTAAGCATGTTTCAAGTGAAACTGATGAAAGTT
GTAAGAAGCACCTTGGAAGAGTGTTATCTATTTGGGAAGAAAGGTCTGTTTATGAAAATGATGTATTAGAACAACTTAAACAAGCTCTGT
ATGGTGATAAGAAGCCTAGGAAGCGAACTTATGAACAGATAAAGGTGGATGAAAATGAAAACTGTTCCTCTCTGGGATCTCCAAGTGAAC
CACCACAGATAATGTGGATGCAAATGATCTTAAGCAGTTTTTTGAGACCAACTATTCTCAGATATATTTCATCTTCTATGAAAATTTTAT
AGCACTGGAAAATAGTTTGAAATTAAAAGGGAATAATAAGTCACAAAGGGAGGAGCTGGACTCCATCCTCTTCCTTTTTGAAAAAATACT
GCAGTTTCTACCTGAACGAATTTTCTTTCGATGGCATTACCAGAGTATAGGCTCAACTTTAAAGAAGCTTCTACACACTGGAAATTCTAT
TAAGATAAGATGTGAAGGAATCAGGCTGTTTCTTCTGTGGCTTCAAGCACTTCAGACAAACTGTGCAGAAGAGCAGGTTCTGATTTTTGC
TTGCCTGGTGCCTGGTTTCCCAGCAGTCATGTCATCCAGGGGCCCTTGCACACTGGAGACACTCATCAATCCCAGCCCTAGTGTAGCTGA
TGTAAAGATATATCCAGAAGAAATCACTCCACTCCTACCAGCCATATCAGGGGAGAAGATTGCTGAGGACCAAACCTGCTTTTTTCTTCA
AATACTGTTGAAGTATATGGTTATTCAGGCTGCGAGCTTGGAGTGGAAGAATAAGGAGAATCAAGATACTGGTTTTAAATTTCTTTTTAC
ATTGTTTCGAAAGTATTATCTTCCTCATTTATTTCCATCATTTACTAAGTTAACAAACATCTACAAACCTGTACTTGACATCCCCCATTT
GAGACCAAAGCCTGTGTACATTACTACCACTCGAGACAATGAGAACATTTACAGTACAAAGATTCCATATATGGCAGCTCGTGTTGTTTT
TATTAAGTGGATTGTAACCTTCTTTTTGGAAAAAAAGTATCTAACTGCAACACAAAACACTAAAAATGGAGTTGATGTATTGCCTAAAAT
CATCCAGACTGTTGGTGGTGGTGCTGTGCAGGAGAGAGCGCCTGAGCTGGATGGTGGTGGGCCCACGGAGCAGGACAAAAGCCATTCTAA
CAGCAGCACCTTGTCGGACCGAAGACTCAGCAACTCCAGCCTCTGTAGCATTGAAGAAGAGCACCGAATGGTGTATGAAATGGTACAGCG
GATTCTCTTGTCAACACGAGGTTATGTCAACTTCGTGAATGAAGTATTTCACCAGGCATTTTTGTTGCCTTCCTGTGAGATAGCTGTAAC
AAGAAAAGTAGTTCAAGTGTACAGAAAGTGGATTCTCCAGGACAAACCTGTGTTCATGGAGGAGCCAGATAGAAAAGATGTTGCCCAAGA
AGATGCTGAAAAATTAGGATTTTCCGAGACTGATAGCAAGGAGGCCTCATCTGAAAGTTCTGGTCATAAACGATCTTCCAGTTGGGGACG
CACATACTCCTTCACAAGTGCAATGAGCAGAGGGTGTGTGACAGAGGAGGAAAATACAAATGTGAAAGCCGGCGTCCAGGCTTTGTTGCA
GGTATTTTTGACGAACTCTGCAAACATCTTTTTGTTGGAACCATGTGCTGAAGTTCCTGTGCTCTTGAAAGAACAAGTTGATGCTTGTAA
AGCTGTTTTGATTATTTTTAGGCGCATGATAATGGAGCTTACAATGAATAAAAAGACATGGGAACAGATGTTGCAAATACTACTCAGGAT
AACAGAAGCTGTCATGCAGAAGCCAAAGGATAAACAAATAAAGGACTTGTTTGCCCAGAGCTTGGCAGGGTTACTATTTAGGACGCTCAT
GGTAGCTTGGATCCGAGCAAACCTCTGTGTGTACATTTCTCGAGAGCTCTGGGATGACTTTCTTGGTGTGCTGTCCTCCCTCACGGAATG
GGAGGAACTTATAAACGAGTGGGCCAACATTATGGACTCCTTGACAGCAGTGCTTGCAAGAACCGTTTATGGAGTTGAGATGACAAACCT
ACCTCTGGATAAATTAAGTGAACAAAAGGAAAAGAAGCAACGAGGCAAAGGCTGTGTTCTAGATCCTCAGAAAGGAACCACCGTGGGGAG
GTCCTTTTCTCTCAGCTGGCGGAGCCACCCAGATGTGACCGAACCGATGCGATTTAGGAGTGCCACCACGTCTGGAGCACCGGGAGTGGA
AAAGGCAAGAAATATTGTTCGCCAAAAAGCAACTGAAGTGGAGGAGTGTCAACAGTCAGAAAATGCACCTGCAGCCGGATCTGGCCATCT
CACAGTGGGACAGCAGCAGCAGGTCCTTCGGAGCAGCAGCACCTCCGACATCCCCGAGCCGCTGTGCTCAGATTCTTCTCAGGGTCAAAA
GGCAGAAAACACACAGAATTCGAGTTCTTCAGAGCCTCAGCCTATTCAAGAGAATAAAGGACATGTGAAGAGAGAACATGAAGGAATAAC
AATCTTAGTTCGAAGAAGCAGCAGCCCTGCTGAATTGGATTTGAAAGATGATTTGCAGCAGACACAAGGAAAATGTAGGGAAAGACAGAA
GAGTGAAAGTACCAACAGTGACACAACTCTGGGCTGTACCAATGAGGCAGAGCTGTCCATGGGCCCATGGCAGACCTGTGAGGAAGACCC
AGAACTGAATACTCCCACAGATGTTGTGGCTGATGCTGATGCCCGTCATTGGTTACAACTGAGTCCCACCGATGCTTCAAATTTAACAGA
TAGCAGCGAGTGCCTCACAGATGACTGTAGTATAATCGCCGGGGGGAGCCTCACTGGTTGGCACCCAGACTCTGCTGCTGTGTTATGGCG
AAGGGTCTTGGGGATCCTCGGAGATGTGAATAACATCCAGTCACCCAAGATCCATGCCAGAGTTTTCTGCTATCTCTATGAACTCTGGTA
CAAACTAGCAAAGATACGGGATAATCTAGCAATAAGCCTGGATAACCAGTCTTCTCCATCTCCTCCAGTTTTGATCCCACCACTCAGAAT
GTTTGCATCATGGCTGTTTAAGGCGGCGACACTGCCAAATGAATATAAGGAAGGCAAACTACAAGCCTACAGGCTGATCTGTGCCATGAT
GACCAGACGCCAGGACGTTCTGCCAAACTCAGATTTCCTGGTGCATTTTTACCTTGTGATGCACCTGGGATTAACCAGCGAGGATCAGGA
TATCTTAAATACGATCATAAGGCACTGTCCACCCCGCTTTTTCTCCCTGGGTTTTCCTGGCTTCTCAATGCTGGTGGGGGACTTCATCAC
GGCCGCTGCCAGGGTCCTTAGCACAGACATTTTGACGGCGCCTCGTTCAGAGGCTGTCACTGTCCTCGGCTCTCTGGTCTGCTTTCCAAA
TACCTACCAGGAGATTCCTTTACTGCAGTCAGTGCCAGAAGTAAATGAGGCCATTACAGGAACTGAAGATGTCAAGCATTACCTCATAAA
TATTTTACTGAAGAATGCCACAGAAGAACCAAATGAATATGCAAGATGCATTGCTGTTTGCTCCCTTGGGGTCTGGATATGTGAAGAGCT
TGCACAGTGTACAAGCCACCCTCAGGTGAAAGAGGCCATCAATGTGATAGGAGTAACTCTGAAGTTTCCCAACAAAATCGTGGCCCAGGT
AGCTTGCGATGTCCTTCAGTTGCTGGTTTCCTACTGGGAGAAGCTTCAGATGTTTGAAACCTCTCTGCCTCGGAAAATGGCAGAAATCCT
CGTGGCCACAGTTGCTTTTCTTTTACCAAGTGCAGAGTACTCCTCAGTGGAAACAGACAAGAAGTTTATTGTGTCCTTGCTACTCTGCCT
CTTGGACTGGTGCATGGCATTGCCCGTGAGTGTCCTTCTCCACCCCGTGTCCACAGCAGTCCTAGAGGAGCAGCATTCGGCCAGAGCCCC
CTTGCTGGATTATATCTACAGGGTTTTGCACTGCTGTGTGTGTGGCTCAAGCACGTACACCCAACAGAGTCACTACATACTGACCCTGGC
TGACTTGTCATCCACGGATTATGACCCCTTCCTGCCACTGGCAAATGTGAAGAGCTCTGAGCCAGTCCAGTATCATTCATCAGCAGAATT
GGGTAACCTGCTGACTGTTGAAGAGGAGAAGAAGAGAAGAAGTTTGGAGTTGATCCCTTTGACTGCTCGAATGGTGATGGCCCACCTGGT
GAACCACCTGGGGCACTACCCCCTCAGTGGGGGCCCTGCCATACTGCACAGCCTTGTCAGCGAGAACCATGACAATGCCCATGTGGAAGG
CTCCGAGCTGTCCTTTGAGGTGTTCAGAAGTCCAAACCTGCAGCTGTTTGTATTTAATGATAGCACCCTCATCTCCTACCTTCAGACACC
CACAGAAGGACCGGTAGGGGGATCACCAGTGGGCTCTCTCTCTGATGTGAGAGTAATTGTGAGGGATATCTCAGGGAAGTACTCTTGGGA
TGGTAAGGTTTTATATGGACCTTTGGAAGGCTGCTTAGCACCCAATGGAAGAAATCCTTCATTTCTGATTTCGAGCTGGCATCGTGACAC
ATTTGGACCTCAGAAAGACTCTTCTCAAGTTGAGGAGGGGGATGATGTTCTTGACAAATTACTTGAAAACATTGGCCATACAAGTCCTGA
ATGCCTTTTACCGTCACAGCTAAATCTAAATGAACCTTCCCTAACCCCATGTGGCATGAACTATGACCAAGAGAAGGAAATCATTGAGGT
CATTTTGCGCCAAAATGCTCAAGAGGATGAGTATATCCAGAGTCATAACTTCGATTCTGCAATGAAAGTCACCAGCCAAGGGCAGCCCTC
CCCAGTGGAGCCCCGAGGACCCTTTTATTTCTGCAGGTTATTGCTTGATGACTTGGGAATGAATTCTTGGGACAGAAGGAAGAATTTTCA
TCTATTGAAGAAAAATTCAAAATTATTGAGAGAGCTGAAAAATTTGGACTCCCGCCAGTGCCGTGAGACACACAAAATCGCAGTGTTTTA
CATTGCTGAAGGTCAAGAAGACAAGTGTTCAATCCTCTCTAATGAAAGAGGAAGCCAAGCATATGAAGACTTTGTTGCTGGACTTGGATG
GGAGGTGGATCTCTCCACCCACTGTGGGTTCATGGGTGGCCTTCAGCGCAATGGCAGCACCGGGCAGACGGCCCCTTACTATGCTACCTC
AACTGTGGAAGTGATTTTCCATGTTTCCACTCGAATGCCGTCAGACTCAGATGATTCCCTCACCAAAAAGCTTCGTCACTTGGGGAATGA
CGAGGTCCATATCGTCTGGTCTGAACACTCCAGAGACTACCGCAGGGGTATTATCCCAACTGCCTTTGGAGATGTTTCAATCATTATTTA
CCCAATGAAGAATCACATGTTCTTCATCGCGATAACGAAGAAACCTGAGGTTCCATTTTTTGGGCCTCTGTTTGATGGAGCCATAGTGAG
TGGGAAGCTGCTGCCAAGCCTTGTATGTGCCACGTGCATCAACGCCAGCAGGGCTGTGAAGTGCCTCATCCCACTCTACCAGAGCTTCTA
TGAAGAGCGAGCTCTGTATCTCGAAGCAATAATTCAGAACCACCGCGAAGTAATGACATTCGAGGATTTCGCAGCCCAAGTCTTTTCTCC
CTCTCCCAGCTACTCCCTCAGCGGAACGGATTAAAACACGTAAAGGTCTCATTTCAATATTTGAGCAAGGGGCCCTGGCCTCCAGTCTGA
GTGCTGACCTCGAAGAGCCCCTGAGTGAGGAGGAGACAGAACACCCTCTCCTGCCTCTGCCCCGAGCCACTAAACCCAGAATCTCCAGGA
AATTTCGTTGCTGTACTAGTGCCCTCAGCAGGTCTTCCCATTAGTGGACTTCTGAAGCCCATGGTGAATCCCACTACCGTGTCTCAGATG
GGACTCAAACTAGGCTGTATCATCTTGTCCTGAAACCTCACAAACCTTGGACTTCCAAAGAAGAAAAGAAAAAGTCACCAAAAACCAGAG
ATGAACCCACTGACACGTGGGCACTGGTGTGGCTGCTCTGGGCAGATGACAGCAGGAAAAGATTCTGCGCTTTCAGGGAGGGGGCAGAGG
GCAGCTTGCTTCTGCACCCCAAGTTGTTTCTTCTCATTTATGAACCCAAGCATGATTCACAAAGGGGCTGGCAAAACAATTGTCTAATTG

>77240_77240_1_RPRD1A-RALGAPA2_RPRD1A_chr18_33610770_ENST00000319040_RALGAPA2_chr20_20661445_ENST00000202677_length(amino acids)=1809AA_BP=
MENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFAC
LVPGFPAVMSSRGPCTLETLINPSPSVADVKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTL
FRKYYLPHLFPSFTKLTNIYKPVLDIPHLRPKPVYITTTRDNENIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKII
QTVGGGAVQERAPELDGGGPTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRMVYEMVQRILLSTRGYVNFVNEVFHQAFLLPSCEIAVTR
KVVQVYRKWILQDKPVFMEEPDRKDVAQEDAEKLGFSETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEENTNVKAGVQALLQV
FLTNSANIFLLEPCAEVPVLLKEQVDACKAVLIIFRRMIMELTMNKKTWEQMLQILLRITEAVMQKPKDKQIKDLFAQSLAGLLFRTLMV
AWIRANLCVYISRELWDDFLGVLSSLTEWEELINEWANIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDPQKGTTVGRS
FSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEECQQSENAPAAGSGHLTVGQQQQVLRSSSTSDIPEPLCSDSSQGQKA
ENTQNSSSSEPQPIQENKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGKCRERQKSESTNSDTTLGCTNEAELSMGPWQTCEEDPE
LNTPTDVVADADARHWLQLSPTDASNLTDSSECLTDDCSIIAGGSLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFCYLYELWYK
LAKIRDNLAISLDNQSSPSPPVLIPPLRMFASWLFKAATLPNEYKEGKLQAYRLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDI
LNTIIRHCPPRFFSLGFPGFSMLVGDFITAAARVLSTDILTAPRSEAVTVLGSLVCFPNTYQEIPLLQSVPEVNEAITGTEDVKHYLINI
LLKNATEEPNEYARCIAVCSLGVWICEELAQCTSHPQVKEAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETSLPRKMAEILV
ATVAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVSVLLHPVSTAVLEEQHSARAPLLDYIYRVLHCCVCGSSTYTQQSHYILTLAD
LSSTDYDPFLPLANVKSSEPVQYHSSAELGNLLTVEEEKKRRSLELIPLTARMVMAHLVNHLGHYPLSGGPAILHSLVSENHDNAHVEGS
ELSFEVFRSPNLQLFVFNDSTLISYLQTPTEGPVGGSPVGSLSDVRVIVRDISGKYSWDGKVLYGPLEGCLAPNGRNPSFLISSWHRDTF
GPQKDSSQVEEGDDVLDKLLENIGHTSPECLLPSQLNLNEPSLTPCGMNYDQEKEIIEVILRQNAQEDEYIQSHNFDSAMKVTSQGQPSP
VEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWE
VDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYP
MKNHMFFIAITKKPEVPFFGPLFDGAIVSGKLLPSLVCATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPS

--------------------------------------------------------------
>77240_77240_2_RPRD1A-RALGAPA2_RPRD1A_chr18_33610770_ENST00000399022_RALGAPA2_chr20_20661445_ENST00000202677_length(transcript)=6696nt_BP=658nt
ACTGCCGGCCGGACGCCATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGG
GGGCGAGGCCGCAGCTAGGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGC
CTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCA
CCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGCCAAACCAAACAGGAAGCTTACTTTTCTCTACCTAGC
CAATGATGTCATACAGAACAGCAAGAGGAAGGGGCCAGAGTTTACAAAAGATTTTGCACCAGTTATAGTGGAGGCTTTTAAGCATGTTTC
AAGTGAAACTGATGAAAGTTGTAAGAAGCACCTTGGAAGAGTGTTATCTATTTGGGAAGAAAGGTCTGTTTATGAAAATGATGTATTAGA
ACAACTTAAACAAGCTCTGTATGGTGATAAGAAGCCTAGGAAGCGAACTTATGAACAGATAAAGGTGGATGAAAATGAAAACTGTTCCTC
TCTGGGATCTCCAAGTGAACCACCACAGATAATGTGGATGCAAATGATCTTAAGCAGTTTTTTGAGACCAACTATTCTCAGATATATTTC
ATCTTCTATGAAAATTTTATAGCACTGGAAAATAGTTTGAAATTAAAAGGGAATAATAAGTCACAAAGGGAGGAGCTGGACTCCATCCTC
TTCCTTTTTGAAAAAATACTGCAGTTTCTACCTGAACGAATTTTCTTTCGATGGCATTACCAGAGTATAGGCTCAACTTTAAAGAAGCTT
CTACACACTGGAAATTCTATTAAGATAAGATGTGAAGGAATCAGGCTGTTTCTTCTGTGGCTTCAAGCACTTCAGACAAACTGTGCAGAA
GAGCAGGTTCTGATTTTTGCTTGCCTGGTGCCTGGTTTCCCAGCAGTCATGTCATCCAGGGGCCCTTGCACACTGGAGACACTCATCAAT
CCCAGCCCTAGTGTAGCTGATGTAAAGATATATCCAGAAGAAATCACTCCACTCCTACCAGCCATATCAGGGGAGAAGATTGCTGAGGAC
CAAACCTGCTTTTTTCTTCAAATACTGTTGAAGTATATGGTTATTCAGGCTGCGAGCTTGGAGTGGAAGAATAAGGAGAATCAAGATACT
GGTTTTAAATTTCTTTTTACATTGTTTCGAAAGTATTATCTTCCTCATTTATTTCCATCATTTACTAAGTTAACAAACATCTACAAACCT
GTACTTGACATCCCCCATTTGAGACCAAAGCCTGTGTACATTACTACCACTCGAGACAATGAGAACATTTACAGTACAAAGATTCCATAT
ATGGCAGCTCGTGTTGTTTTTATTAAGTGGATTGTAACCTTCTTTTTGGAAAAAAAGTATCTAACTGCAACACAAAACACTAAAAATGGA
GTTGATGTATTGCCTAAAATCATCCAGACTGTTGGTGGTGGTGCTGTGCAGGAGAGAGCGCCTGAGCTGGATGGTGGTGGGCCCACGGAG
CAGGACAAAAGCCATTCTAACAGCAGCACCTTGTCGGACCGAAGACTCAGCAACTCCAGCCTCTGTAGCATTGAAGAAGAGCACCGAATG
GTGTATGAAATGGTACAGCGGATTCTCTTGTCAACACGAGGTTATGTCAACTTCGTGAATGAAGTATTTCACCAGGCATTTTTGTTGCCT
TCCTGTGAGATAGCTGTAACAAGAAAAGTAGTTCAAGTGTACAGAAAGTGGATTCTCCAGGACAAACCTGTGTTCATGGAGGAGCCAGAT
AGAAAAGATGTTGCCCAAGAAGATGCTGAAAAATTAGGATTTTCCGAGACTGATAGCAAGGAGGCCTCATCTGAAAGTTCTGGTCATAAA
CGATCTTCCAGTTGGGGACGCACATACTCCTTCACAAGTGCAATGAGCAGAGGGTGTGTGACAGAGGAGGAAAATACAAATGTGAAAGCC
GGCGTCCAGGCTTTGTTGCAGGTATTTTTGACGAACTCTGCAAACATCTTTTTGTTGGAACCATGTGCTGAAGTTCCTGTGCTCTTGAAA
GAACAAGTTGATGCTTGTAAAGCTGTTTTGATTATTTTTAGGCGCATGATAATGGAGCTTACAATGAATAAAAAGACATGGGAACAGATG
TTGCAAATACTACTCAGGATAACAGAAGCTGTCATGCAGAAGCCAAAGGATAAACAAATAAAGGACTTGTTTGCCCAGAGCTTGGCAGGG
TTACTATTTAGGACGCTCATGGTAGCTTGGATCCGAGCAAACCTCTGTGTGTACATTTCTCGAGAGCTCTGGGATGACTTTCTTGGTGTG
CTGTCCTCCCTCACGGAATGGGAGGAACTTATAAACGAGTGGGCCAACATTATGGACTCCTTGACAGCAGTGCTTGCAAGAACCGTTTAT
GGAGTTGAGATGACAAACCTACCTCTGGATAAATTAAGTGAACAAAAGGAAAAGAAGCAACGAGGCAAAGGCTGTGTTCTAGATCCTCAG
AAAGGAACCACCGTGGGGAGGTCCTTTTCTCTCAGCTGGCGGAGCCACCCAGATGTGACCGAACCGATGCGATTTAGGAGTGCCACCACG
TCTGGAGCACCGGGAGTGGAAAAGGCAAGAAATATTGTTCGCCAAAAAGCAACTGAAGTGGAGGAGTGTCAACAGTCAGAAAATGCACCT
GCAGCCGGATCTGGCCATCTCACAGTGGGACAGCAGCAGCAGGTCCTTCGGAGCAGCAGCACCTCCGACATCCCCGAGCCGCTGTGCTCA
GATTCTTCTCAGGGTCAAAAGGCAGAAAACACACAGAATTCGAGTTCTTCAGAGCCTCAGCCTATTCAAGAGAATAAAGGACATGTGAAG
AGAGAACATGAAGGAATAACAATCTTAGTTCGAAGAAGCAGCAGCCCTGCTGAATTGGATTTGAAAGATGATTTGCAGCAGACACAAGGA
AAATGTAGGGAAAGACAGAAGAGTGAAAGTACCAACAGTGACACAACTCTGGGCTGTACCAATGAGGCAGAGCTGTCCATGGGCCCATGG
CAGACCTGTGAGGAAGACCCAGAACTGAATACTCCCACAGATGTTGTGGCTGATGCTGATGCCCGTCATTGGTTACAACTGAGTCCCACC
GATGCTTCAAATTTAACAGATAGCAGCGAGTGCCTCACAGATGACTGTAGTATAATCGCCGGGGGGAGCCTCACTGGTTGGCACCCAGAC
TCTGCTGCTGTGTTATGGCGAAGGGTCTTGGGGATCCTCGGAGATGTGAATAACATCCAGTCACCCAAGATCCATGCCAGAGTTTTCTGC
TATCTCTATGAACTCTGGTACAAACTAGCAAAGATACGGGATAATCTAGCAATAAGCCTGGATAACCAGTCTTCTCCATCTCCTCCAGTT
TTGATCCCACCACTCAGAATGTTTGCATCATGGCTGTTTAAGGCGGCGACACTGCCAAATGAATATAAGGAAGGCAAACTACAAGCCTAC
AGGCTGATCTGTGCCATGATGACCAGACGCCAGGACGTTCTGCCAAACTCAGATTTCCTGGTGCATTTTTACCTTGTGATGCACCTGGGA
TTAACCAGCGAGGATCAGGATATCTTAAATACGATCATAAGGCACTGTCCACCCCGCTTTTTCTCCCTGGGTTTTCCTGGCTTCTCAATG
CTGGTGGGGGACTTCATCACGGCCGCTGCCAGGGTCCTTAGCACAGACATTTTGACGGCGCCTCGTTCAGAGGCTGTCACTGTCCTCGGC
TCTCTGGTCTGCTTTCCAAATACCTACCAGGAGATTCCTTTACTGCAGTCAGTGCCAGAAGTAAATGAGGCCATTACAGGAACTGAAGAT
GTCAAGCATTACCTCATAAATATTTTACTGAAGAATGCCACAGAAGAACCAAATGAATATGCAAGATGCATTGCTGTTTGCTCCCTTGGG
GTCTGGATATGTGAAGAGCTTGCACAGTGTACAAGCCACCCTCAGGTGAAAGAGGCCATCAATGTGATAGGAGTAACTCTGAAGTTTCCC
AACAAAATCGTGGCCCAGGTAGCTTGCGATGTCCTTCAGTTGCTGGTTTCCTACTGGGAGAAGCTTCAGATGTTTGAAACCTCTCTGCCT
CGGAAAATGGCAGAAATCCTCGTGGCCACAGTTGCTTTTCTTTTACCAAGTGCAGAGTACTCCTCAGTGGAAACAGACAAGAAGTTTATT
GTGTCCTTGCTACTCTGCCTCTTGGACTGGTGCATGGCATTGCCCGTGAGTGTCCTTCTCCACCCCGTGTCCACAGCAGTCCTAGAGGAG
CAGCATTCGGCCAGAGCCCCCTTGCTGGATTATATCTACAGGGTTTTGCACTGCTGTGTGTGTGGCTCAAGCACGTACACCCAACAGAGT
CACTACATACTGACCCTGGCTGACTTGTCATCCACGGATTATGACCCCTTCCTGCCACTGGCAAATGTGAAGAGCTCTGAGCCAGTCCAG
TATCATTCATCAGCAGAATTGGGTAACCTGCTGACTGTTGAAGAGGAGAAGAAGAGAAGAAGTTTGGAGTTGATCCCTTTGACTGCTCGA
ATGGTGATGGCCCACCTGGTGAACCACCTGGGGCACTACCCCCTCAGTGGGGGCCCTGCCATACTGCACAGCCTTGTCAGCGAGAACCAT
GACAATGCCCATGTGGAAGGCTCCGAGCTGTCCTTTGAGGTGTTCAGAAGTCCAAACCTGCAGCTGTTTGTATTTAATGATAGCACCCTC
ATCTCCTACCTTCAGACACCCACAGAAGGACCGGTAGGGGGATCACCAGTGGGCTCTCTCTCTGATGTGAGAGTAATTGTGAGGGATATC
TCAGGGAAGTACTCTTGGGATGGTAAGGTTTTATATGGACCTTTGGAAGGCTGCTTAGCACCCAATGGAAGAAATCCTTCATTTCTGATT
TCGAGCTGGCATCGTGACACATTTGGACCTCAGAAAGACTCTTCTCAAGTTGAGGAGGGGGATGATGTTCTTGACAAATTACTTGAAAAC
ATTGGCCATACAAGTCCTGAATGCCTTTTACCGTCACAGCTAAATCTAAATGAACCTTCCCTAACCCCATGTGGCATGAACTATGACCAA
GAGAAGGAAATCATTGAGGTCATTTTGCGCCAAAATGCTCAAGAGGATGAGTATATCCAGAGTCATAACTTCGATTCTGCAATGAAAGTC
ACCAGCCAAGGGCAGCCCTCCCCAGTGGAGCCCCGAGGACCCTTTTATTTCTGCAGGTTATTGCTTGATGACTTGGGAATGAATTCTTGG
GACAGAAGGAAGAATTTTCATCTATTGAAGAAAAATTCAAAATTATTGAGAGAGCTGAAAAATTTGGACTCCCGCCAGTGCCGTGAGACA
CACAAAATCGCAGTGTTTTACATTGCTGAAGGTCAAGAAGACAAGTGTTCAATCCTCTCTAATGAAAGAGGAAGCCAAGCATATGAAGAC
TTTGTTGCTGGACTTGGATGGGAGGTGGATCTCTCCACCCACTGTGGGTTCATGGGTGGCCTTCAGCGCAATGGCAGCACCGGGCAGACG
GCCCCTTACTATGCTACCTCAACTGTGGAAGTGATTTTCCATGTTTCCACTCGAATGCCGTCAGACTCAGATGATTCCCTCACCAAAAAG
CTTCGTCACTTGGGGAATGACGAGGTCCATATCGTCTGGTCTGAACACTCCAGAGACTACCGCAGGGGTATTATCCCAACTGCCTTTGGA
GATGTTTCAATCATTATTTACCCAATGAAGAATCACATGTTCTTCATCGCGATAACGAAGAAACCTGAGGTTCCATTTTTTGGGCCTCTG
TTTGATGGAGCCATAGTGAGTGGGAAGCTGCTGCCAAGCCTTGTATGTGCCACGTGCATCAACGCCAGCAGGGCTGTGAAGTGCCTCATC
CCACTCTACCAGAGCTTCTATGAAGAGCGAGCTCTGTATCTCGAAGCAATAATTCAGAACCACCGCGAAGTAATGACATTCGAGGATTTC
GCAGCCCAAGTCTTTTCTCCCTCTCCCAGCTACTCCCTCAGCGGAACGGATTAAAACACGTAAAGGTCTCATTTCAATATTTGAGCAAGG
GGCCCTGGCCTCCAGTCTGAGTGCTGACCTCGAAGAGCCCCTGAGTGAGGAGGAGACAGAACACCCTCTCCTGCCTCTGCCCCGAGCCAC
TAAACCCAGAATCTCCAGGAAATTTCGTTGCTGTACTAGTGCCCTCAGCAGGTCTTCCCATTAGTGGACTTCTGAAGCCCATGGTGAATC
CCACTACCGTGTCTCAGATGGGACTCAAACTAGGCTGTATCATCTTGTCCTGAAACCTCACAAACCTTGGACTTCCAAAGAAGAAAAGAA
AAAGTCACCAAAAACCAGAGATGAACCCACTGACACGTGGGCACTGGTGTGGCTGCTCTGGGCAGATGACAGCAGGAAAAGATTCTGCGC
TTTCAGGGAGGGGGCAGAGGGCAGCTTGCTTCTGCACCCCAAGTTGTTTCTTCTCATTTATGAACCCAAGCATGATTCACAAAGGGGCTG

>77240_77240_2_RPRD1A-RALGAPA2_RPRD1A_chr18_33610770_ENST00000399022_RALGAPA2_chr20_20661445_ENST00000202677_length(amino acids)=1809AA_BP=
MENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFAC
LVPGFPAVMSSRGPCTLETLINPSPSVADVKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTL
FRKYYLPHLFPSFTKLTNIYKPVLDIPHLRPKPVYITTTRDNENIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKII
QTVGGGAVQERAPELDGGGPTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRMVYEMVQRILLSTRGYVNFVNEVFHQAFLLPSCEIAVTR
KVVQVYRKWILQDKPVFMEEPDRKDVAQEDAEKLGFSETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEENTNVKAGVQALLQV
FLTNSANIFLLEPCAEVPVLLKEQVDACKAVLIIFRRMIMELTMNKKTWEQMLQILLRITEAVMQKPKDKQIKDLFAQSLAGLLFRTLMV
AWIRANLCVYISRELWDDFLGVLSSLTEWEELINEWANIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDPQKGTTVGRS
FSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEECQQSENAPAAGSGHLTVGQQQQVLRSSSTSDIPEPLCSDSSQGQKA
ENTQNSSSSEPQPIQENKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGKCRERQKSESTNSDTTLGCTNEAELSMGPWQTCEEDPE
LNTPTDVVADADARHWLQLSPTDASNLTDSSECLTDDCSIIAGGSLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFCYLYELWYK
LAKIRDNLAISLDNQSSPSPPVLIPPLRMFASWLFKAATLPNEYKEGKLQAYRLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDI
LNTIIRHCPPRFFSLGFPGFSMLVGDFITAAARVLSTDILTAPRSEAVTVLGSLVCFPNTYQEIPLLQSVPEVNEAITGTEDVKHYLINI
LLKNATEEPNEYARCIAVCSLGVWICEELAQCTSHPQVKEAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETSLPRKMAEILV
ATVAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVSVLLHPVSTAVLEEQHSARAPLLDYIYRVLHCCVCGSSTYTQQSHYILTLAD
LSSTDYDPFLPLANVKSSEPVQYHSSAELGNLLTVEEEKKRRSLELIPLTARMVMAHLVNHLGHYPLSGGPAILHSLVSENHDNAHVEGS
ELSFEVFRSPNLQLFVFNDSTLISYLQTPTEGPVGGSPVGSLSDVRVIVRDISGKYSWDGKVLYGPLEGCLAPNGRNPSFLISSWHRDTF
GPQKDSSQVEEGDDVLDKLLENIGHTSPECLLPSQLNLNEPSLTPCGMNYDQEKEIIEVILRQNAQEDEYIQSHNFDSAMKVTSQGQPSP
VEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWE
VDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYP
MKNHMFFIAITKKPEVPFFGPLFDGAIVSGKLLPSLVCATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPS

--------------------------------------------------------------
>77240_77240_3_RPRD1A-RALGAPA2_RPRD1A_chr18_33610770_ENST00000588737_RALGAPA2_chr20_20661445_ENST00000202677_length(transcript)=6738nt_BP=700nt
ATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTA
GGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGC
TGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTC
CCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGAGTGGAGGTGCAACAAATGAGAAATTCCAATTGGAGATTTTGTCAAACAGGAAT
TTACTCCAAACCAAACAGGAAGCTTACTTTTCTCTACCTAGCCAATGATGTCATACAGAACAGCAAGAGGAAGGGGCCAGAGTTTACAAA
AGATTTTGCACCAGTTATAGTGGAGGCTTTTAAGCATGTTTCAAGTGAAACTGATGAAAGTTGTAAGAAGCACCTTGGAAGAGTGTTATC
TATTTGGGAAGAAAGGTCTGTTTATGAAAATGATGTATTAGAACAACTTAAACAAGCTCTGTATGGTGATAAGAAGCCTAGGAAGCGAAC
TTATGAACAGATAAAGGTGGATGAAAATGAAAACTGTTCCTCTCTGGGATCTCCAAGTGAACCACCACAGATAATGTGGATGCAAATGAT
CTTAAGCAGTTTTTTGAGACCAACTATTCTCAGATATATTTCATCTTCTATGAAAATTTTATAGCACTGGAAAATAGTTTGAAATTAAAA
GGGAATAATAAGTCACAAAGGGAGGAGCTGGACTCCATCCTCTTCCTTTTTGAAAAAATACTGCAGTTTCTACCTGAACGAATTTTCTTT
CGATGGCATTACCAGAGTATAGGCTCAACTTTAAAGAAGCTTCTACACACTGGAAATTCTATTAAGATAAGATGTGAAGGAATCAGGCTG
TTTCTTCTGTGGCTTCAAGCACTTCAGACAAACTGTGCAGAAGAGCAGGTTCTGATTTTTGCTTGCCTGGTGCCTGGTTTCCCAGCAGTC
ATGTCATCCAGGGGCCCTTGCACACTGGAGACACTCATCAATCCCAGCCCTAGTGTAGCTGATGTAAAGATATATCCAGAAGAAATCACT
CCACTCCTACCAGCCATATCAGGGGAGAAGATTGCTGAGGACCAAACCTGCTTTTTTCTTCAAATACTGTTGAAGTATATGGTTATTCAG
GCTGCGAGCTTGGAGTGGAAGAATAAGGAGAATCAAGATACTGGTTTTAAATTTCTTTTTACATTGTTTCGAAAGTATTATCTTCCTCAT
TTATTTCCATCATTTACTAAGTTAACAAACATCTACAAACCTGTACTTGACATCCCCCATTTGAGACCAAAGCCTGTGTACATTACTACC
ACTCGAGACAATGAGAACATTTACAGTACAAAGATTCCATATATGGCAGCTCGTGTTGTTTTTATTAAGTGGATTGTAACCTTCTTTTTG
GAAAAAAAGTATCTAACTGCAACACAAAACACTAAAAATGGAGTTGATGTATTGCCTAAAATCATCCAGACTGTTGGTGGTGGTGCTGTG
CAGGAGAGAGCGCCTGAGCTGGATGGTGGTGGGCCCACGGAGCAGGACAAAAGCCATTCTAACAGCAGCACCTTGTCGGACCGAAGACTC
AGCAACTCCAGCCTCTGTAGCATTGAAGAAGAGCACCGAATGGTGTATGAAATGGTACAGCGGATTCTCTTGTCAACACGAGGTTATGTC
AACTTCGTGAATGAAGTATTTCACCAGGCATTTTTGTTGCCTTCCTGTGAGATAGCTGTAACAAGAAAAGTAGTTCAAGTGTACAGAAAG
TGGATTCTCCAGGACAAACCTGTGTTCATGGAGGAGCCAGATAGAAAAGATGTTGCCCAAGAAGATGCTGAAAAATTAGGATTTTCCGAG
ACTGATAGCAAGGAGGCCTCATCTGAAAGTTCTGGTCATAAACGATCTTCCAGTTGGGGACGCACATACTCCTTCACAAGTGCAATGAGC
AGAGGGTGTGTGACAGAGGAGGAAAATACAAATGTGAAAGCCGGCGTCCAGGCTTTGTTGCAGGTATTTTTGACGAACTCTGCAAACATC
TTTTTGTTGGAACCATGTGCTGAAGTTCCTGTGCTCTTGAAAGAACAAGTTGATGCTTGTAAAGCTGTTTTGATTATTTTTAGGCGCATG
ATAATGGAGCTTACAATGAATAAAAAGACATGGGAACAGATGTTGCAAATACTACTCAGGATAACAGAAGCTGTCATGCAGAAGCCAAAG
GATAAACAAATAAAGGACTTGTTTGCCCAGAGCTTGGCAGGGTTACTATTTAGGACGCTCATGGTAGCTTGGATCCGAGCAAACCTCTGT
GTGTACATTTCTCGAGAGCTCTGGGATGACTTTCTTGGTGTGCTGTCCTCCCTCACGGAATGGGAGGAACTTATAAACGAGTGGGCCAAC
ATTATGGACTCCTTGACAGCAGTGCTTGCAAGAACCGTTTATGGAGTTGAGATGACAAACCTACCTCTGGATAAATTAAGTGAACAAAAG
GAAAAGAAGCAACGAGGCAAAGGCTGTGTTCTAGATCCTCAGAAAGGAACCACCGTGGGGAGGTCCTTTTCTCTCAGCTGGCGGAGCCAC
CCAGATGTGACCGAACCGATGCGATTTAGGAGTGCCACCACGTCTGGAGCACCGGGAGTGGAAAAGGCAAGAAATATTGTTCGCCAAAAA
GCAACTGAAGTGGAGGAGTGTCAACAGTCAGAAAATGCACCTGCAGCCGGATCTGGCCATCTCACAGTGGGACAGCAGCAGCAGGTCCTT
CGGAGCAGCAGCACCTCCGACATCCCCGAGCCGCTGTGCTCAGATTCTTCTCAGGGTCAAAAGGCAGAAAACACACAGAATTCGAGTTCT
TCAGAGCCTCAGCCTATTCAAGAGAATAAAGGACATGTGAAGAGAGAACATGAAGGAATAACAATCTTAGTTCGAAGAAGCAGCAGCCCT
GCTGAATTGGATTTGAAAGATGATTTGCAGCAGACACAAGGAAAATGTAGGGAAAGACAGAAGAGTGAAAGTACCAACAGTGACACAACT
CTGGGCTGTACCAATGAGGCAGAGCTGTCCATGGGCCCATGGCAGACCTGTGAGGAAGACCCAGAACTGAATACTCCCACAGATGTTGTG
GCTGATGCTGATGCCCGTCATTGGTTACAACTGAGTCCCACCGATGCTTCAAATTTAACAGATAGCAGCGAGTGCCTCACAGATGACTGT
AGTATAATCGCCGGGGGGAGCCTCACTGGTTGGCACCCAGACTCTGCTGCTGTGTTATGGCGAAGGGTCTTGGGGATCCTCGGAGATGTG
AATAACATCCAGTCACCCAAGATCCATGCCAGAGTTTTCTGCTATCTCTATGAACTCTGGTACAAACTAGCAAAGATACGGGATAATCTA
GCAATAAGCCTGGATAACCAGTCTTCTCCATCTCCTCCAGTTTTGATCCCACCACTCAGAATGTTTGCATCATGGCTGTTTAAGGCGGCG
ACACTGCCAAATGAATATAAGGAAGGCAAACTACAAGCCTACAGGCTGATCTGTGCCATGATGACCAGACGCCAGGACGTTCTGCCAAAC
TCAGATTTCCTGGTGCATTTTTACCTTGTGATGCACCTGGGATTAACCAGCGAGGATCAGGATATCTTAAATACGATCATAAGGCACTGT
CCACCCCGCTTTTTCTCCCTGGGTTTTCCTGGCTTCTCAATGCTGGTGGGGGACTTCATCACGGCCGCTGCCAGGGTCCTTAGCACAGAC
ATTTTGACGGCGCCTCGTTCAGAGGCTGTCACTGTCCTCGGCTCTCTGGTCTGCTTTCCAAATACCTACCAGGAGATTCCTTTACTGCAG
TCAGTGCCAGAAGTAAATGAGGCCATTACAGGAACTGAAGATGTCAAGCATTACCTCATAAATATTTTACTGAAGAATGCCACAGAAGAA
CCAAATGAATATGCAAGATGCATTGCTGTTTGCTCCCTTGGGGTCTGGATATGTGAAGAGCTTGCACAGTGTACAAGCCACCCTCAGGTG
AAAGAGGCCATCAATGTGATAGGAGTAACTCTGAAGTTTCCCAACAAAATCGTGGCCCAGGTAGCTTGCGATGTCCTTCAGTTGCTGGTT
TCCTACTGGGAGAAGCTTCAGATGTTTGAAACCTCTCTGCCTCGGAAAATGGCAGAAATCCTCGTGGCCACAGTTGCTTTTCTTTTACCA
AGTGCAGAGTACTCCTCAGTGGAAACAGACAAGAAGTTTATTGTGTCCTTGCTACTCTGCCTCTTGGACTGGTGCATGGCATTGCCCGTG
AGTGTCCTTCTCCACCCCGTGTCCACAGCAGTCCTAGAGGAGCAGCATTCGGCCAGAGCCCCCTTGCTGGATTATATCTACAGGGTTTTG
CACTGCTGTGTGTGTGGCTCAAGCACGTACACCCAACAGAGTCACTACATACTGACCCTGGCTGACTTGTCATCCACGGATTATGACCCC
TTCCTGCCACTGGCAAATGTGAAGAGCTCTGAGCCAGTCCAGTATCATTCATCAGCAGAATTGGGTAACCTGCTGACTGTTGAAGAGGAG
AAGAAGAGAAGAAGTTTGGAGTTGATCCCTTTGACTGCTCGAATGGTGATGGCCCACCTGGTGAACCACCTGGGGCACTACCCCCTCAGT
GGGGGCCCTGCCATACTGCACAGCCTTGTCAGCGAGAACCATGACAATGCCCATGTGGAAGGCTCCGAGCTGTCCTTTGAGGTGTTCAGA
AGTCCAAACCTGCAGCTGTTTGTATTTAATGATAGCACCCTCATCTCCTACCTTCAGACACCCACAGAAGGACCGGTAGGGGGATCACCA
GTGGGCTCTCTCTCTGATGTGAGAGTAATTGTGAGGGATATCTCAGGGAAGTACTCTTGGGATGGTAAGGTTTTATATGGACCTTTGGAA
GGCTGCTTAGCACCCAATGGAAGAAATCCTTCATTTCTGATTTCGAGCTGGCATCGTGACACATTTGGACCTCAGAAAGACTCTTCTCAA
GTTGAGGAGGGGGATGATGTTCTTGACAAATTACTTGAAAACATTGGCCATACAAGTCCTGAATGCCTTTTACCGTCACAGCTAAATCTA
AATGAACCTTCCCTAACCCCATGTGGCATGAACTATGACCAAGAGAAGGAAATCATTGAGGTCATTTTGCGCCAAAATGCTCAAGAGGAT
GAGTATATCCAGAGTCATAACTTCGATTCTGCAATGAAAGTCACCAGCCAAGGGCAGCCCTCCCCAGTGGAGCCCCGAGGACCCTTTTAT
TTCTGCAGGTTATTGCTTGATGACTTGGGAATGAATTCTTGGGACAGAAGGAAGAATTTTCATCTATTGAAGAAAAATTCAAAATTATTG
AGAGAGCTGAAAAATTTGGACTCCCGCCAGTGCCGTGAGACACACAAAATCGCAGTGTTTTACATTGCTGAAGGTCAAGAAGACAAGTGT
TCAATCCTCTCTAATGAAAGAGGAAGCCAAGCATATGAAGACTTTGTTGCTGGACTTGGATGGGAGGTGGATCTCTCCACCCACTGTGGG
TTCATGGGTGGCCTTCAGCGCAATGGCAGCACCGGGCAGACGGCCCCTTACTATGCTACCTCAACTGTGGAAGTGATTTTCCATGTTTCC
ACTCGAATGCCGTCAGACTCAGATGATTCCCTCACCAAAAAGCTTCGTCACTTGGGGAATGACGAGGTCCATATCGTCTGGTCTGAACAC
TCCAGAGACTACCGCAGGGGTATTATCCCAACTGCCTTTGGAGATGTTTCAATCATTATTTACCCAATGAAGAATCACATGTTCTTCATC
GCGATAACGAAGAAACCTGAGGTTCCATTTTTTGGGCCTCTGTTTGATGGAGCCATAGTGAGTGGGAAGCTGCTGCCAAGCCTTGTATGT
GCCACGTGCATCAACGCCAGCAGGGCTGTGAAGTGCCTCATCCCACTCTACCAGAGCTTCTATGAAGAGCGAGCTCTGTATCTCGAAGCA
ATAATTCAGAACCACCGCGAAGTAATGACATTCGAGGATTTCGCAGCCCAAGTCTTTTCTCCCTCTCCCAGCTACTCCCTCAGCGGAACG
GATTAAAACACGTAAAGGTCTCATTTCAATATTTGAGCAAGGGGCCCTGGCCTCCAGTCTGAGTGCTGACCTCGAAGAGCCCCTGAGTGA
GGAGGAGACAGAACACCCTCTCCTGCCTCTGCCCCGAGCCACTAAACCCAGAATCTCCAGGAAATTTCGTTGCTGTACTAGTGCCCTCAG
CAGGTCTTCCCATTAGTGGACTTCTGAAGCCCATGGTGAATCCCACTACCGTGTCTCAGATGGGACTCAAACTAGGCTGTATCATCTTGT
CCTGAAACCTCACAAACCTTGGACTTCCAAAGAAGAAAAGAAAAAGTCACCAAAAACCAGAGATGAACCCACTGACACGTGGGCACTGGT
GTGGCTGCTCTGGGCAGATGACAGCAGGAAAAGATTCTGCGCTTTCAGGGAGGGGGCAGAGGGCAGCTTGCTTCTGCACCCCAAGTTGTT

>77240_77240_3_RPRD1A-RALGAPA2_RPRD1A_chr18_33610770_ENST00000588737_RALGAPA2_chr20_20661445_ENST00000202677_length(amino acids)=1809AA_BP=
MENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFAC
LVPGFPAVMSSRGPCTLETLINPSPSVADVKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTL
FRKYYLPHLFPSFTKLTNIYKPVLDIPHLRPKPVYITTTRDNENIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKII
QTVGGGAVQERAPELDGGGPTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRMVYEMVQRILLSTRGYVNFVNEVFHQAFLLPSCEIAVTR
KVVQVYRKWILQDKPVFMEEPDRKDVAQEDAEKLGFSETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEENTNVKAGVQALLQV
FLTNSANIFLLEPCAEVPVLLKEQVDACKAVLIIFRRMIMELTMNKKTWEQMLQILLRITEAVMQKPKDKQIKDLFAQSLAGLLFRTLMV
AWIRANLCVYISRELWDDFLGVLSSLTEWEELINEWANIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDPQKGTTVGRS
FSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEECQQSENAPAAGSGHLTVGQQQQVLRSSSTSDIPEPLCSDSSQGQKA
ENTQNSSSSEPQPIQENKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGKCRERQKSESTNSDTTLGCTNEAELSMGPWQTCEEDPE
LNTPTDVVADADARHWLQLSPTDASNLTDSSECLTDDCSIIAGGSLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFCYLYELWYK
LAKIRDNLAISLDNQSSPSPPVLIPPLRMFASWLFKAATLPNEYKEGKLQAYRLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDI
LNTIIRHCPPRFFSLGFPGFSMLVGDFITAAARVLSTDILTAPRSEAVTVLGSLVCFPNTYQEIPLLQSVPEVNEAITGTEDVKHYLINI
LLKNATEEPNEYARCIAVCSLGVWICEELAQCTSHPQVKEAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETSLPRKMAEILV
ATVAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVSVLLHPVSTAVLEEQHSARAPLLDYIYRVLHCCVCGSSTYTQQSHYILTLAD
LSSTDYDPFLPLANVKSSEPVQYHSSAELGNLLTVEEEKKRRSLELIPLTARMVMAHLVNHLGHYPLSGGPAILHSLVSENHDNAHVEGS
ELSFEVFRSPNLQLFVFNDSTLISYLQTPTEGPVGGSPVGSLSDVRVIVRDISGKYSWDGKVLYGPLEGCLAPNGRNPSFLISSWHRDTF
GPQKDSSQVEEGDDVLDKLLENIGHTSPECLLPSQLNLNEPSLTPCGMNYDQEKEIIEVILRQNAQEDEYIQSHNFDSAMKVTSQGQPSP
VEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWE
VDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYP
MKNHMFFIAITKKPEVPFFGPLFDGAIVSGKLLPSLVCATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPS

--------------------------------------------------------------
>77240_77240_4_RPRD1A-RALGAPA2_RPRD1A_chr18_33610771_ENST00000319040_RALGAPA2_chr20_20661445_ENST00000202677_length(transcript)=6676nt_BP=638nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGCCAAACCAAACAGGAAGCTTACTTTTCTCTACCTAGCCAATGATGTCATACAGAACA
GCAAGAGGAAGGGGCCAGAGTTTACAAAAGATTTTGCACCAGTTATAGTGGAGGCTTTTAAGCATGTTTCAAGTGAAACTGATGAAAGTT
GTAAGAAGCACCTTGGAAGAGTGTTATCTATTTGGGAAGAAAGGTCTGTTTATGAAAATGATGTATTAGAACAACTTAAACAAGCTCTGT
ATGGTGATAAGAAGCCTAGGAAGCGAACTTATGAACAGATAAAGGTGGATGAAAATGAAAACTGTTCCTCTCTGGGATCTCCAAGTGAAC
CACCACAGATAATGTGGATGCAAATGATCTTAAGCAGTTTTTTGAGACCAACTATTCTCAGATATATTTCATCTTCTATGAAAATTTTAT
AGCACTGGAAAATAGTTTGAAATTAAAAGGGAATAATAAGTCACAAAGGGAGGAGCTGGACTCCATCCTCTTCCTTTTTGAAAAAATACT
GCAGTTTCTACCTGAACGAATTTTCTTTCGATGGCATTACCAGAGTATAGGCTCAACTTTAAAGAAGCTTCTACACACTGGAAATTCTAT
TAAGATAAGATGTGAAGGAATCAGGCTGTTTCTTCTGTGGCTTCAAGCACTTCAGACAAACTGTGCAGAAGAGCAGGTTCTGATTTTTGC
TTGCCTGGTGCCTGGTTTCCCAGCAGTCATGTCATCCAGGGGCCCTTGCACACTGGAGACACTCATCAATCCCAGCCCTAGTGTAGCTGA
TGTAAAGATATATCCAGAAGAAATCACTCCACTCCTACCAGCCATATCAGGGGAGAAGATTGCTGAGGACCAAACCTGCTTTTTTCTTCA
AATACTGTTGAAGTATATGGTTATTCAGGCTGCGAGCTTGGAGTGGAAGAATAAGGAGAATCAAGATACTGGTTTTAAATTTCTTTTTAC
ATTGTTTCGAAAGTATTATCTTCCTCATTTATTTCCATCATTTACTAAGTTAACAAACATCTACAAACCTGTACTTGACATCCCCCATTT
GAGACCAAAGCCTGTGTACATTACTACCACTCGAGACAATGAGAACATTTACAGTACAAAGATTCCATATATGGCAGCTCGTGTTGTTTT
TATTAAGTGGATTGTAACCTTCTTTTTGGAAAAAAAGTATCTAACTGCAACACAAAACACTAAAAATGGAGTTGATGTATTGCCTAAAAT
CATCCAGACTGTTGGTGGTGGTGCTGTGCAGGAGAGAGCGCCTGAGCTGGATGGTGGTGGGCCCACGGAGCAGGACAAAAGCCATTCTAA
CAGCAGCACCTTGTCGGACCGAAGACTCAGCAACTCCAGCCTCTGTAGCATTGAAGAAGAGCACCGAATGGTGTATGAAATGGTACAGCG
GATTCTCTTGTCAACACGAGGTTATGTCAACTTCGTGAATGAAGTATTTCACCAGGCATTTTTGTTGCCTTCCTGTGAGATAGCTGTAAC
AAGAAAAGTAGTTCAAGTGTACAGAAAGTGGATTCTCCAGGACAAACCTGTGTTCATGGAGGAGCCAGATAGAAAAGATGTTGCCCAAGA
AGATGCTGAAAAATTAGGATTTTCCGAGACTGATAGCAAGGAGGCCTCATCTGAAAGTTCTGGTCATAAACGATCTTCCAGTTGGGGACG
CACATACTCCTTCACAAGTGCAATGAGCAGAGGGTGTGTGACAGAGGAGGAAAATACAAATGTGAAAGCCGGCGTCCAGGCTTTGTTGCA
GGTATTTTTGACGAACTCTGCAAACATCTTTTTGTTGGAACCATGTGCTGAAGTTCCTGTGCTCTTGAAAGAACAAGTTGATGCTTGTAA
AGCTGTTTTGATTATTTTTAGGCGCATGATAATGGAGCTTACAATGAATAAAAAGACATGGGAACAGATGTTGCAAATACTACTCAGGAT
AACAGAAGCTGTCATGCAGAAGCCAAAGGATAAACAAATAAAGGACTTGTTTGCCCAGAGCTTGGCAGGGTTACTATTTAGGACGCTCAT
GGTAGCTTGGATCCGAGCAAACCTCTGTGTGTACATTTCTCGAGAGCTCTGGGATGACTTTCTTGGTGTGCTGTCCTCCCTCACGGAATG
GGAGGAACTTATAAACGAGTGGGCCAACATTATGGACTCCTTGACAGCAGTGCTTGCAAGAACCGTTTATGGAGTTGAGATGACAAACCT
ACCTCTGGATAAATTAAGTGAACAAAAGGAAAAGAAGCAACGAGGCAAAGGCTGTGTTCTAGATCCTCAGAAAGGAACCACCGTGGGGAG
GTCCTTTTCTCTCAGCTGGCGGAGCCACCCAGATGTGACCGAACCGATGCGATTTAGGAGTGCCACCACGTCTGGAGCACCGGGAGTGGA
AAAGGCAAGAAATATTGTTCGCCAAAAAGCAACTGAAGTGGAGGAGTGTCAACAGTCAGAAAATGCACCTGCAGCCGGATCTGGCCATCT
CACAGTGGGACAGCAGCAGCAGGTCCTTCGGAGCAGCAGCACCTCCGACATCCCCGAGCCGCTGTGCTCAGATTCTTCTCAGGGTCAAAA
GGCAGAAAACACACAGAATTCGAGTTCTTCAGAGCCTCAGCCTATTCAAGAGAATAAAGGACATGTGAAGAGAGAACATGAAGGAATAAC
AATCTTAGTTCGAAGAAGCAGCAGCCCTGCTGAATTGGATTTGAAAGATGATTTGCAGCAGACACAAGGAAAATGTAGGGAAAGACAGAA
GAGTGAAAGTACCAACAGTGACACAACTCTGGGCTGTACCAATGAGGCAGAGCTGTCCATGGGCCCATGGCAGACCTGTGAGGAAGACCC
AGAACTGAATACTCCCACAGATGTTGTGGCTGATGCTGATGCCCGTCATTGGTTACAACTGAGTCCCACCGATGCTTCAAATTTAACAGA
TAGCAGCGAGTGCCTCACAGATGACTGTAGTATAATCGCCGGGGGGAGCCTCACTGGTTGGCACCCAGACTCTGCTGCTGTGTTATGGCG
AAGGGTCTTGGGGATCCTCGGAGATGTGAATAACATCCAGTCACCCAAGATCCATGCCAGAGTTTTCTGCTATCTCTATGAACTCTGGTA
CAAACTAGCAAAGATACGGGATAATCTAGCAATAAGCCTGGATAACCAGTCTTCTCCATCTCCTCCAGTTTTGATCCCACCACTCAGAAT
GTTTGCATCATGGCTGTTTAAGGCGGCGACACTGCCAAATGAATATAAGGAAGGCAAACTACAAGCCTACAGGCTGATCTGTGCCATGAT
GACCAGACGCCAGGACGTTCTGCCAAACTCAGATTTCCTGGTGCATTTTTACCTTGTGATGCACCTGGGATTAACCAGCGAGGATCAGGA
TATCTTAAATACGATCATAAGGCACTGTCCACCCCGCTTTTTCTCCCTGGGTTTTCCTGGCTTCTCAATGCTGGTGGGGGACTTCATCAC
GGCCGCTGCCAGGGTCCTTAGCACAGACATTTTGACGGCGCCTCGTTCAGAGGCTGTCACTGTCCTCGGCTCTCTGGTCTGCTTTCCAAA
TACCTACCAGGAGATTCCTTTACTGCAGTCAGTGCCAGAAGTAAATGAGGCCATTACAGGAACTGAAGATGTCAAGCATTACCTCATAAA
TATTTTACTGAAGAATGCCACAGAAGAACCAAATGAATATGCAAGATGCATTGCTGTTTGCTCCCTTGGGGTCTGGATATGTGAAGAGCT
TGCACAGTGTACAAGCCACCCTCAGGTGAAAGAGGCCATCAATGTGATAGGAGTAACTCTGAAGTTTCCCAACAAAATCGTGGCCCAGGT
AGCTTGCGATGTCCTTCAGTTGCTGGTTTCCTACTGGGAGAAGCTTCAGATGTTTGAAACCTCTCTGCCTCGGAAAATGGCAGAAATCCT
CGTGGCCACAGTTGCTTTTCTTTTACCAAGTGCAGAGTACTCCTCAGTGGAAACAGACAAGAAGTTTATTGTGTCCTTGCTACTCTGCCT
CTTGGACTGGTGCATGGCATTGCCCGTGAGTGTCCTTCTCCACCCCGTGTCCACAGCAGTCCTAGAGGAGCAGCATTCGGCCAGAGCCCC
CTTGCTGGATTATATCTACAGGGTTTTGCACTGCTGTGTGTGTGGCTCAAGCACGTACACCCAACAGAGTCACTACATACTGACCCTGGC
TGACTTGTCATCCACGGATTATGACCCCTTCCTGCCACTGGCAAATGTGAAGAGCTCTGAGCCAGTCCAGTATCATTCATCAGCAGAATT
GGGTAACCTGCTGACTGTTGAAGAGGAGAAGAAGAGAAGAAGTTTGGAGTTGATCCCTTTGACTGCTCGAATGGTGATGGCCCACCTGGT
GAACCACCTGGGGCACTACCCCCTCAGTGGGGGCCCTGCCATACTGCACAGCCTTGTCAGCGAGAACCATGACAATGCCCATGTGGAAGG
CTCCGAGCTGTCCTTTGAGGTGTTCAGAAGTCCAAACCTGCAGCTGTTTGTATTTAATGATAGCACCCTCATCTCCTACCTTCAGACACC
CACAGAAGGACCGGTAGGGGGATCACCAGTGGGCTCTCTCTCTGATGTGAGAGTAATTGTGAGGGATATCTCAGGGAAGTACTCTTGGGA
TGGTAAGGTTTTATATGGACCTTTGGAAGGCTGCTTAGCACCCAATGGAAGAAATCCTTCATTTCTGATTTCGAGCTGGCATCGTGACAC
ATTTGGACCTCAGAAAGACTCTTCTCAAGTTGAGGAGGGGGATGATGTTCTTGACAAATTACTTGAAAACATTGGCCATACAAGTCCTGA
ATGCCTTTTACCGTCACAGCTAAATCTAAATGAACCTTCCCTAACCCCATGTGGCATGAACTATGACCAAGAGAAGGAAATCATTGAGGT
CATTTTGCGCCAAAATGCTCAAGAGGATGAGTATATCCAGAGTCATAACTTCGATTCTGCAATGAAAGTCACCAGCCAAGGGCAGCCCTC
CCCAGTGGAGCCCCGAGGACCCTTTTATTTCTGCAGGTTATTGCTTGATGACTTGGGAATGAATTCTTGGGACAGAAGGAAGAATTTTCA
TCTATTGAAGAAAAATTCAAAATTATTGAGAGAGCTGAAAAATTTGGACTCCCGCCAGTGCCGTGAGACACACAAAATCGCAGTGTTTTA
CATTGCTGAAGGTCAAGAAGACAAGTGTTCAATCCTCTCTAATGAAAGAGGAAGCCAAGCATATGAAGACTTTGTTGCTGGACTTGGATG
GGAGGTGGATCTCTCCACCCACTGTGGGTTCATGGGTGGCCTTCAGCGCAATGGCAGCACCGGGCAGACGGCCCCTTACTATGCTACCTC
AACTGTGGAAGTGATTTTCCATGTTTCCACTCGAATGCCGTCAGACTCAGATGATTCCCTCACCAAAAAGCTTCGTCACTTGGGGAATGA
CGAGGTCCATATCGTCTGGTCTGAACACTCCAGAGACTACCGCAGGGGTATTATCCCAACTGCCTTTGGAGATGTTTCAATCATTATTTA
CCCAATGAAGAATCACATGTTCTTCATCGCGATAACGAAGAAACCTGAGGTTCCATTTTTTGGGCCTCTGTTTGATGGAGCCATAGTGAG
TGGGAAGCTGCTGCCAAGCCTTGTATGTGCCACGTGCATCAACGCCAGCAGGGCTGTGAAGTGCCTCATCCCACTCTACCAGAGCTTCTA
TGAAGAGCGAGCTCTGTATCTCGAAGCAATAATTCAGAACCACCGCGAAGTAATGACATTCGAGGATTTCGCAGCCCAAGTCTTTTCTCC
CTCTCCCAGCTACTCCCTCAGCGGAACGGATTAAAACACGTAAAGGTCTCATTTCAATATTTGAGCAAGGGGCCCTGGCCTCCAGTCTGA
GTGCTGACCTCGAAGAGCCCCTGAGTGAGGAGGAGACAGAACACCCTCTCCTGCCTCTGCCCCGAGCCACTAAACCCAGAATCTCCAGGA
AATTTCGTTGCTGTACTAGTGCCCTCAGCAGGTCTTCCCATTAGTGGACTTCTGAAGCCCATGGTGAATCCCACTACCGTGTCTCAGATG
GGACTCAAACTAGGCTGTATCATCTTGTCCTGAAACCTCACAAACCTTGGACTTCCAAAGAAGAAAAGAAAAAGTCACCAAAAACCAGAG
ATGAACCCACTGACACGTGGGCACTGGTGTGGCTGCTCTGGGCAGATGACAGCAGGAAAAGATTCTGCGCTTTCAGGGAGGGGGCAGAGG
GCAGCTTGCTTCTGCACCCCAAGTTGTTTCTTCTCATTTATGAACCCAAGCATGATTCACAAAGGGGCTGGCAAAACAATTGTCTAATTG

>77240_77240_4_RPRD1A-RALGAPA2_RPRD1A_chr18_33610771_ENST00000319040_RALGAPA2_chr20_20661445_ENST00000202677_length(amino acids)=1809AA_BP=
MENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFAC
LVPGFPAVMSSRGPCTLETLINPSPSVADVKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTL
FRKYYLPHLFPSFTKLTNIYKPVLDIPHLRPKPVYITTTRDNENIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKII
QTVGGGAVQERAPELDGGGPTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRMVYEMVQRILLSTRGYVNFVNEVFHQAFLLPSCEIAVTR
KVVQVYRKWILQDKPVFMEEPDRKDVAQEDAEKLGFSETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEENTNVKAGVQALLQV
FLTNSANIFLLEPCAEVPVLLKEQVDACKAVLIIFRRMIMELTMNKKTWEQMLQILLRITEAVMQKPKDKQIKDLFAQSLAGLLFRTLMV
AWIRANLCVYISRELWDDFLGVLSSLTEWEELINEWANIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDPQKGTTVGRS
FSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEECQQSENAPAAGSGHLTVGQQQQVLRSSSTSDIPEPLCSDSSQGQKA
ENTQNSSSSEPQPIQENKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGKCRERQKSESTNSDTTLGCTNEAELSMGPWQTCEEDPE
LNTPTDVVADADARHWLQLSPTDASNLTDSSECLTDDCSIIAGGSLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFCYLYELWYK
LAKIRDNLAISLDNQSSPSPPVLIPPLRMFASWLFKAATLPNEYKEGKLQAYRLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDI
LNTIIRHCPPRFFSLGFPGFSMLVGDFITAAARVLSTDILTAPRSEAVTVLGSLVCFPNTYQEIPLLQSVPEVNEAITGTEDVKHYLINI
LLKNATEEPNEYARCIAVCSLGVWICEELAQCTSHPQVKEAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETSLPRKMAEILV
ATVAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVSVLLHPVSTAVLEEQHSARAPLLDYIYRVLHCCVCGSSTYTQQSHYILTLAD
LSSTDYDPFLPLANVKSSEPVQYHSSAELGNLLTVEEEKKRRSLELIPLTARMVMAHLVNHLGHYPLSGGPAILHSLVSENHDNAHVEGS
ELSFEVFRSPNLQLFVFNDSTLISYLQTPTEGPVGGSPVGSLSDVRVIVRDISGKYSWDGKVLYGPLEGCLAPNGRNPSFLISSWHRDTF
GPQKDSSQVEEGDDVLDKLLENIGHTSPECLLPSQLNLNEPSLTPCGMNYDQEKEIIEVILRQNAQEDEYIQSHNFDSAMKVTSQGQPSP
VEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWE
VDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYP
MKNHMFFIAITKKPEVPFFGPLFDGAIVSGKLLPSLVCATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPS

--------------------------------------------------------------
>77240_77240_5_RPRD1A-RALGAPA2_RPRD1A_chr18_33610771_ENST00000399022_RALGAPA2_chr20_20661445_ENST00000202677_length(transcript)=6696nt_BP=658nt
ACTGCCGGCCGGACGCCATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGG
GGGCGAGGCCGCAGCTAGGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGC
CTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCA
CCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGCCAAACCAAACAGGAAGCTTACTTTTCTCTACCTAGC
CAATGATGTCATACAGAACAGCAAGAGGAAGGGGCCAGAGTTTACAAAAGATTTTGCACCAGTTATAGTGGAGGCTTTTAAGCATGTTTC
AAGTGAAACTGATGAAAGTTGTAAGAAGCACCTTGGAAGAGTGTTATCTATTTGGGAAGAAAGGTCTGTTTATGAAAATGATGTATTAGA
ACAACTTAAACAAGCTCTGTATGGTGATAAGAAGCCTAGGAAGCGAACTTATGAACAGATAAAGGTGGATGAAAATGAAAACTGTTCCTC
TCTGGGATCTCCAAGTGAACCACCACAGATAATGTGGATGCAAATGATCTTAAGCAGTTTTTTGAGACCAACTATTCTCAGATATATTTC
ATCTTCTATGAAAATTTTATAGCACTGGAAAATAGTTTGAAATTAAAAGGGAATAATAAGTCACAAAGGGAGGAGCTGGACTCCATCCTC
TTCCTTTTTGAAAAAATACTGCAGTTTCTACCTGAACGAATTTTCTTTCGATGGCATTACCAGAGTATAGGCTCAACTTTAAAGAAGCTT
CTACACACTGGAAATTCTATTAAGATAAGATGTGAAGGAATCAGGCTGTTTCTTCTGTGGCTTCAAGCACTTCAGACAAACTGTGCAGAA
GAGCAGGTTCTGATTTTTGCTTGCCTGGTGCCTGGTTTCCCAGCAGTCATGTCATCCAGGGGCCCTTGCACACTGGAGACACTCATCAAT
CCCAGCCCTAGTGTAGCTGATGTAAAGATATATCCAGAAGAAATCACTCCACTCCTACCAGCCATATCAGGGGAGAAGATTGCTGAGGAC
CAAACCTGCTTTTTTCTTCAAATACTGTTGAAGTATATGGTTATTCAGGCTGCGAGCTTGGAGTGGAAGAATAAGGAGAATCAAGATACT
GGTTTTAAATTTCTTTTTACATTGTTTCGAAAGTATTATCTTCCTCATTTATTTCCATCATTTACTAAGTTAACAAACATCTACAAACCT
GTACTTGACATCCCCCATTTGAGACCAAAGCCTGTGTACATTACTACCACTCGAGACAATGAGAACATTTACAGTACAAAGATTCCATAT
ATGGCAGCTCGTGTTGTTTTTATTAAGTGGATTGTAACCTTCTTTTTGGAAAAAAAGTATCTAACTGCAACACAAAACACTAAAAATGGA
GTTGATGTATTGCCTAAAATCATCCAGACTGTTGGTGGTGGTGCTGTGCAGGAGAGAGCGCCTGAGCTGGATGGTGGTGGGCCCACGGAG
CAGGACAAAAGCCATTCTAACAGCAGCACCTTGTCGGACCGAAGACTCAGCAACTCCAGCCTCTGTAGCATTGAAGAAGAGCACCGAATG
GTGTATGAAATGGTACAGCGGATTCTCTTGTCAACACGAGGTTATGTCAACTTCGTGAATGAAGTATTTCACCAGGCATTTTTGTTGCCT
TCCTGTGAGATAGCTGTAACAAGAAAAGTAGTTCAAGTGTACAGAAAGTGGATTCTCCAGGACAAACCTGTGTTCATGGAGGAGCCAGAT
AGAAAAGATGTTGCCCAAGAAGATGCTGAAAAATTAGGATTTTCCGAGACTGATAGCAAGGAGGCCTCATCTGAAAGTTCTGGTCATAAA
CGATCTTCCAGTTGGGGACGCACATACTCCTTCACAAGTGCAATGAGCAGAGGGTGTGTGACAGAGGAGGAAAATACAAATGTGAAAGCC
GGCGTCCAGGCTTTGTTGCAGGTATTTTTGACGAACTCTGCAAACATCTTTTTGTTGGAACCATGTGCTGAAGTTCCTGTGCTCTTGAAA
GAACAAGTTGATGCTTGTAAAGCTGTTTTGATTATTTTTAGGCGCATGATAATGGAGCTTACAATGAATAAAAAGACATGGGAACAGATG
TTGCAAATACTACTCAGGATAACAGAAGCTGTCATGCAGAAGCCAAAGGATAAACAAATAAAGGACTTGTTTGCCCAGAGCTTGGCAGGG
TTACTATTTAGGACGCTCATGGTAGCTTGGATCCGAGCAAACCTCTGTGTGTACATTTCTCGAGAGCTCTGGGATGACTTTCTTGGTGTG
CTGTCCTCCCTCACGGAATGGGAGGAACTTATAAACGAGTGGGCCAACATTATGGACTCCTTGACAGCAGTGCTTGCAAGAACCGTTTAT
GGAGTTGAGATGACAAACCTACCTCTGGATAAATTAAGTGAACAAAAGGAAAAGAAGCAACGAGGCAAAGGCTGTGTTCTAGATCCTCAG
AAAGGAACCACCGTGGGGAGGTCCTTTTCTCTCAGCTGGCGGAGCCACCCAGATGTGACCGAACCGATGCGATTTAGGAGTGCCACCACG
TCTGGAGCACCGGGAGTGGAAAAGGCAAGAAATATTGTTCGCCAAAAAGCAACTGAAGTGGAGGAGTGTCAACAGTCAGAAAATGCACCT
GCAGCCGGATCTGGCCATCTCACAGTGGGACAGCAGCAGCAGGTCCTTCGGAGCAGCAGCACCTCCGACATCCCCGAGCCGCTGTGCTCA
GATTCTTCTCAGGGTCAAAAGGCAGAAAACACACAGAATTCGAGTTCTTCAGAGCCTCAGCCTATTCAAGAGAATAAAGGACATGTGAAG
AGAGAACATGAAGGAATAACAATCTTAGTTCGAAGAAGCAGCAGCCCTGCTGAATTGGATTTGAAAGATGATTTGCAGCAGACACAAGGA
AAATGTAGGGAAAGACAGAAGAGTGAAAGTACCAACAGTGACACAACTCTGGGCTGTACCAATGAGGCAGAGCTGTCCATGGGCCCATGG
CAGACCTGTGAGGAAGACCCAGAACTGAATACTCCCACAGATGTTGTGGCTGATGCTGATGCCCGTCATTGGTTACAACTGAGTCCCACC
GATGCTTCAAATTTAACAGATAGCAGCGAGTGCCTCACAGATGACTGTAGTATAATCGCCGGGGGGAGCCTCACTGGTTGGCACCCAGAC
TCTGCTGCTGTGTTATGGCGAAGGGTCTTGGGGATCCTCGGAGATGTGAATAACATCCAGTCACCCAAGATCCATGCCAGAGTTTTCTGC
TATCTCTATGAACTCTGGTACAAACTAGCAAAGATACGGGATAATCTAGCAATAAGCCTGGATAACCAGTCTTCTCCATCTCCTCCAGTT
TTGATCCCACCACTCAGAATGTTTGCATCATGGCTGTTTAAGGCGGCGACACTGCCAAATGAATATAAGGAAGGCAAACTACAAGCCTAC
AGGCTGATCTGTGCCATGATGACCAGACGCCAGGACGTTCTGCCAAACTCAGATTTCCTGGTGCATTTTTACCTTGTGATGCACCTGGGA
TTAACCAGCGAGGATCAGGATATCTTAAATACGATCATAAGGCACTGTCCACCCCGCTTTTTCTCCCTGGGTTTTCCTGGCTTCTCAATG
CTGGTGGGGGACTTCATCACGGCCGCTGCCAGGGTCCTTAGCACAGACATTTTGACGGCGCCTCGTTCAGAGGCTGTCACTGTCCTCGGC
TCTCTGGTCTGCTTTCCAAATACCTACCAGGAGATTCCTTTACTGCAGTCAGTGCCAGAAGTAAATGAGGCCATTACAGGAACTGAAGAT
GTCAAGCATTACCTCATAAATATTTTACTGAAGAATGCCACAGAAGAACCAAATGAATATGCAAGATGCATTGCTGTTTGCTCCCTTGGG
GTCTGGATATGTGAAGAGCTTGCACAGTGTACAAGCCACCCTCAGGTGAAAGAGGCCATCAATGTGATAGGAGTAACTCTGAAGTTTCCC
AACAAAATCGTGGCCCAGGTAGCTTGCGATGTCCTTCAGTTGCTGGTTTCCTACTGGGAGAAGCTTCAGATGTTTGAAACCTCTCTGCCT
CGGAAAATGGCAGAAATCCTCGTGGCCACAGTTGCTTTTCTTTTACCAAGTGCAGAGTACTCCTCAGTGGAAACAGACAAGAAGTTTATT
GTGTCCTTGCTACTCTGCCTCTTGGACTGGTGCATGGCATTGCCCGTGAGTGTCCTTCTCCACCCCGTGTCCACAGCAGTCCTAGAGGAG
CAGCATTCGGCCAGAGCCCCCTTGCTGGATTATATCTACAGGGTTTTGCACTGCTGTGTGTGTGGCTCAAGCACGTACACCCAACAGAGT
CACTACATACTGACCCTGGCTGACTTGTCATCCACGGATTATGACCCCTTCCTGCCACTGGCAAATGTGAAGAGCTCTGAGCCAGTCCAG
TATCATTCATCAGCAGAATTGGGTAACCTGCTGACTGTTGAAGAGGAGAAGAAGAGAAGAAGTTTGGAGTTGATCCCTTTGACTGCTCGA
ATGGTGATGGCCCACCTGGTGAACCACCTGGGGCACTACCCCCTCAGTGGGGGCCCTGCCATACTGCACAGCCTTGTCAGCGAGAACCAT
GACAATGCCCATGTGGAAGGCTCCGAGCTGTCCTTTGAGGTGTTCAGAAGTCCAAACCTGCAGCTGTTTGTATTTAATGATAGCACCCTC
ATCTCCTACCTTCAGACACCCACAGAAGGACCGGTAGGGGGATCACCAGTGGGCTCTCTCTCTGATGTGAGAGTAATTGTGAGGGATATC
TCAGGGAAGTACTCTTGGGATGGTAAGGTTTTATATGGACCTTTGGAAGGCTGCTTAGCACCCAATGGAAGAAATCCTTCATTTCTGATT
TCGAGCTGGCATCGTGACACATTTGGACCTCAGAAAGACTCTTCTCAAGTTGAGGAGGGGGATGATGTTCTTGACAAATTACTTGAAAAC
ATTGGCCATACAAGTCCTGAATGCCTTTTACCGTCACAGCTAAATCTAAATGAACCTTCCCTAACCCCATGTGGCATGAACTATGACCAA
GAGAAGGAAATCATTGAGGTCATTTTGCGCCAAAATGCTCAAGAGGATGAGTATATCCAGAGTCATAACTTCGATTCTGCAATGAAAGTC
ACCAGCCAAGGGCAGCCCTCCCCAGTGGAGCCCCGAGGACCCTTTTATTTCTGCAGGTTATTGCTTGATGACTTGGGAATGAATTCTTGG
GACAGAAGGAAGAATTTTCATCTATTGAAGAAAAATTCAAAATTATTGAGAGAGCTGAAAAATTTGGACTCCCGCCAGTGCCGTGAGACA
CACAAAATCGCAGTGTTTTACATTGCTGAAGGTCAAGAAGACAAGTGTTCAATCCTCTCTAATGAAAGAGGAAGCCAAGCATATGAAGAC
TTTGTTGCTGGACTTGGATGGGAGGTGGATCTCTCCACCCACTGTGGGTTCATGGGTGGCCTTCAGCGCAATGGCAGCACCGGGCAGACG
GCCCCTTACTATGCTACCTCAACTGTGGAAGTGATTTTCCATGTTTCCACTCGAATGCCGTCAGACTCAGATGATTCCCTCACCAAAAAG
CTTCGTCACTTGGGGAATGACGAGGTCCATATCGTCTGGTCTGAACACTCCAGAGACTACCGCAGGGGTATTATCCCAACTGCCTTTGGA
GATGTTTCAATCATTATTTACCCAATGAAGAATCACATGTTCTTCATCGCGATAACGAAGAAACCTGAGGTTCCATTTTTTGGGCCTCTG
TTTGATGGAGCCATAGTGAGTGGGAAGCTGCTGCCAAGCCTTGTATGTGCCACGTGCATCAACGCCAGCAGGGCTGTGAAGTGCCTCATC
CCACTCTACCAGAGCTTCTATGAAGAGCGAGCTCTGTATCTCGAAGCAATAATTCAGAACCACCGCGAAGTAATGACATTCGAGGATTTC
GCAGCCCAAGTCTTTTCTCCCTCTCCCAGCTACTCCCTCAGCGGAACGGATTAAAACACGTAAAGGTCTCATTTCAATATTTGAGCAAGG
GGCCCTGGCCTCCAGTCTGAGTGCTGACCTCGAAGAGCCCCTGAGTGAGGAGGAGACAGAACACCCTCTCCTGCCTCTGCCCCGAGCCAC
TAAACCCAGAATCTCCAGGAAATTTCGTTGCTGTACTAGTGCCCTCAGCAGGTCTTCCCATTAGTGGACTTCTGAAGCCCATGGTGAATC
CCACTACCGTGTCTCAGATGGGACTCAAACTAGGCTGTATCATCTTGTCCTGAAACCTCACAAACCTTGGACTTCCAAAGAAGAAAAGAA
AAAGTCACCAAAAACCAGAGATGAACCCACTGACACGTGGGCACTGGTGTGGCTGCTCTGGGCAGATGACAGCAGGAAAAGATTCTGCGC
TTTCAGGGAGGGGGCAGAGGGCAGCTTGCTTCTGCACCCCAAGTTGTTTCTTCTCATTTATGAACCCAAGCATGATTCACAAAGGGGCTG

>77240_77240_5_RPRD1A-RALGAPA2_RPRD1A_chr18_33610771_ENST00000399022_RALGAPA2_chr20_20661445_ENST00000202677_length(amino acids)=1809AA_BP=
MENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFAC
LVPGFPAVMSSRGPCTLETLINPSPSVADVKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTL
FRKYYLPHLFPSFTKLTNIYKPVLDIPHLRPKPVYITTTRDNENIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKII
QTVGGGAVQERAPELDGGGPTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRMVYEMVQRILLSTRGYVNFVNEVFHQAFLLPSCEIAVTR
KVVQVYRKWILQDKPVFMEEPDRKDVAQEDAEKLGFSETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEENTNVKAGVQALLQV
FLTNSANIFLLEPCAEVPVLLKEQVDACKAVLIIFRRMIMELTMNKKTWEQMLQILLRITEAVMQKPKDKQIKDLFAQSLAGLLFRTLMV
AWIRANLCVYISRELWDDFLGVLSSLTEWEELINEWANIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDPQKGTTVGRS
FSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEECQQSENAPAAGSGHLTVGQQQQVLRSSSTSDIPEPLCSDSSQGQKA
ENTQNSSSSEPQPIQENKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGKCRERQKSESTNSDTTLGCTNEAELSMGPWQTCEEDPE
LNTPTDVVADADARHWLQLSPTDASNLTDSSECLTDDCSIIAGGSLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFCYLYELWYK
LAKIRDNLAISLDNQSSPSPPVLIPPLRMFASWLFKAATLPNEYKEGKLQAYRLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDI
LNTIIRHCPPRFFSLGFPGFSMLVGDFITAAARVLSTDILTAPRSEAVTVLGSLVCFPNTYQEIPLLQSVPEVNEAITGTEDVKHYLINI
LLKNATEEPNEYARCIAVCSLGVWICEELAQCTSHPQVKEAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETSLPRKMAEILV
ATVAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVSVLLHPVSTAVLEEQHSARAPLLDYIYRVLHCCVCGSSTYTQQSHYILTLAD
LSSTDYDPFLPLANVKSSEPVQYHSSAELGNLLTVEEEKKRRSLELIPLTARMVMAHLVNHLGHYPLSGGPAILHSLVSENHDNAHVEGS
ELSFEVFRSPNLQLFVFNDSTLISYLQTPTEGPVGGSPVGSLSDVRVIVRDISGKYSWDGKVLYGPLEGCLAPNGRNPSFLISSWHRDTF
GPQKDSSQVEEGDDVLDKLLENIGHTSPECLLPSQLNLNEPSLTPCGMNYDQEKEIIEVILRQNAQEDEYIQSHNFDSAMKVTSQGQPSP
VEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWE
VDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYP
MKNHMFFIAITKKPEVPFFGPLFDGAIVSGKLLPSLVCATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPS

--------------------------------------------------------------
>77240_77240_6_RPRD1A-RALGAPA2_RPRD1A_chr18_33610771_ENST00000588737_RALGAPA2_chr20_20661445_ENST00000202677_length(transcript)=6738nt_BP=700nt
ATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTA
GGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGC
TGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTC
CCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGAGTGGAGGTGCAACAAATGAGAAATTCCAATTGGAGATTTTGTCAAACAGGAAT
TTACTCCAAACCAAACAGGAAGCTTACTTTTCTCTACCTAGCCAATGATGTCATACAGAACAGCAAGAGGAAGGGGCCAGAGTTTACAAA
AGATTTTGCACCAGTTATAGTGGAGGCTTTTAAGCATGTTTCAAGTGAAACTGATGAAAGTTGTAAGAAGCACCTTGGAAGAGTGTTATC
TATTTGGGAAGAAAGGTCTGTTTATGAAAATGATGTATTAGAACAACTTAAACAAGCTCTGTATGGTGATAAGAAGCCTAGGAAGCGAAC
TTATGAACAGATAAAGGTGGATGAAAATGAAAACTGTTCCTCTCTGGGATCTCCAAGTGAACCACCACAGATAATGTGGATGCAAATGAT
CTTAAGCAGTTTTTTGAGACCAACTATTCTCAGATATATTTCATCTTCTATGAAAATTTTATAGCACTGGAAAATAGTTTGAAATTAAAA
GGGAATAATAAGTCACAAAGGGAGGAGCTGGACTCCATCCTCTTCCTTTTTGAAAAAATACTGCAGTTTCTACCTGAACGAATTTTCTTT
CGATGGCATTACCAGAGTATAGGCTCAACTTTAAAGAAGCTTCTACACACTGGAAATTCTATTAAGATAAGATGTGAAGGAATCAGGCTG
TTTCTTCTGTGGCTTCAAGCACTTCAGACAAACTGTGCAGAAGAGCAGGTTCTGATTTTTGCTTGCCTGGTGCCTGGTTTCCCAGCAGTC
ATGTCATCCAGGGGCCCTTGCACACTGGAGACACTCATCAATCCCAGCCCTAGTGTAGCTGATGTAAAGATATATCCAGAAGAAATCACT
CCACTCCTACCAGCCATATCAGGGGAGAAGATTGCTGAGGACCAAACCTGCTTTTTTCTTCAAATACTGTTGAAGTATATGGTTATTCAG
GCTGCGAGCTTGGAGTGGAAGAATAAGGAGAATCAAGATACTGGTTTTAAATTTCTTTTTACATTGTTTCGAAAGTATTATCTTCCTCAT
TTATTTCCATCATTTACTAAGTTAACAAACATCTACAAACCTGTACTTGACATCCCCCATTTGAGACCAAAGCCTGTGTACATTACTACC
ACTCGAGACAATGAGAACATTTACAGTACAAAGATTCCATATATGGCAGCTCGTGTTGTTTTTATTAAGTGGATTGTAACCTTCTTTTTG
GAAAAAAAGTATCTAACTGCAACACAAAACACTAAAAATGGAGTTGATGTATTGCCTAAAATCATCCAGACTGTTGGTGGTGGTGCTGTG
CAGGAGAGAGCGCCTGAGCTGGATGGTGGTGGGCCCACGGAGCAGGACAAAAGCCATTCTAACAGCAGCACCTTGTCGGACCGAAGACTC
AGCAACTCCAGCCTCTGTAGCATTGAAGAAGAGCACCGAATGGTGTATGAAATGGTACAGCGGATTCTCTTGTCAACACGAGGTTATGTC
AACTTCGTGAATGAAGTATTTCACCAGGCATTTTTGTTGCCTTCCTGTGAGATAGCTGTAACAAGAAAAGTAGTTCAAGTGTACAGAAAG
TGGATTCTCCAGGACAAACCTGTGTTCATGGAGGAGCCAGATAGAAAAGATGTTGCCCAAGAAGATGCTGAAAAATTAGGATTTTCCGAG
ACTGATAGCAAGGAGGCCTCATCTGAAAGTTCTGGTCATAAACGATCTTCCAGTTGGGGACGCACATACTCCTTCACAAGTGCAATGAGC
AGAGGGTGTGTGACAGAGGAGGAAAATACAAATGTGAAAGCCGGCGTCCAGGCTTTGTTGCAGGTATTTTTGACGAACTCTGCAAACATC
TTTTTGTTGGAACCATGTGCTGAAGTTCCTGTGCTCTTGAAAGAACAAGTTGATGCTTGTAAAGCTGTTTTGATTATTTTTAGGCGCATG
ATAATGGAGCTTACAATGAATAAAAAGACATGGGAACAGATGTTGCAAATACTACTCAGGATAACAGAAGCTGTCATGCAGAAGCCAAAG
GATAAACAAATAAAGGACTTGTTTGCCCAGAGCTTGGCAGGGTTACTATTTAGGACGCTCATGGTAGCTTGGATCCGAGCAAACCTCTGT
GTGTACATTTCTCGAGAGCTCTGGGATGACTTTCTTGGTGTGCTGTCCTCCCTCACGGAATGGGAGGAACTTATAAACGAGTGGGCCAAC
ATTATGGACTCCTTGACAGCAGTGCTTGCAAGAACCGTTTATGGAGTTGAGATGACAAACCTACCTCTGGATAAATTAAGTGAACAAAAG
GAAAAGAAGCAACGAGGCAAAGGCTGTGTTCTAGATCCTCAGAAAGGAACCACCGTGGGGAGGTCCTTTTCTCTCAGCTGGCGGAGCCAC
CCAGATGTGACCGAACCGATGCGATTTAGGAGTGCCACCACGTCTGGAGCACCGGGAGTGGAAAAGGCAAGAAATATTGTTCGCCAAAAA
GCAACTGAAGTGGAGGAGTGTCAACAGTCAGAAAATGCACCTGCAGCCGGATCTGGCCATCTCACAGTGGGACAGCAGCAGCAGGTCCTT
CGGAGCAGCAGCACCTCCGACATCCCCGAGCCGCTGTGCTCAGATTCTTCTCAGGGTCAAAAGGCAGAAAACACACAGAATTCGAGTTCT
TCAGAGCCTCAGCCTATTCAAGAGAATAAAGGACATGTGAAGAGAGAACATGAAGGAATAACAATCTTAGTTCGAAGAAGCAGCAGCCCT
GCTGAATTGGATTTGAAAGATGATTTGCAGCAGACACAAGGAAAATGTAGGGAAAGACAGAAGAGTGAAAGTACCAACAGTGACACAACT
CTGGGCTGTACCAATGAGGCAGAGCTGTCCATGGGCCCATGGCAGACCTGTGAGGAAGACCCAGAACTGAATACTCCCACAGATGTTGTG
GCTGATGCTGATGCCCGTCATTGGTTACAACTGAGTCCCACCGATGCTTCAAATTTAACAGATAGCAGCGAGTGCCTCACAGATGACTGT
AGTATAATCGCCGGGGGGAGCCTCACTGGTTGGCACCCAGACTCTGCTGCTGTGTTATGGCGAAGGGTCTTGGGGATCCTCGGAGATGTG
AATAACATCCAGTCACCCAAGATCCATGCCAGAGTTTTCTGCTATCTCTATGAACTCTGGTACAAACTAGCAAAGATACGGGATAATCTA
GCAATAAGCCTGGATAACCAGTCTTCTCCATCTCCTCCAGTTTTGATCCCACCACTCAGAATGTTTGCATCATGGCTGTTTAAGGCGGCG
ACACTGCCAAATGAATATAAGGAAGGCAAACTACAAGCCTACAGGCTGATCTGTGCCATGATGACCAGACGCCAGGACGTTCTGCCAAAC
TCAGATTTCCTGGTGCATTTTTACCTTGTGATGCACCTGGGATTAACCAGCGAGGATCAGGATATCTTAAATACGATCATAAGGCACTGT
CCACCCCGCTTTTTCTCCCTGGGTTTTCCTGGCTTCTCAATGCTGGTGGGGGACTTCATCACGGCCGCTGCCAGGGTCCTTAGCACAGAC
ATTTTGACGGCGCCTCGTTCAGAGGCTGTCACTGTCCTCGGCTCTCTGGTCTGCTTTCCAAATACCTACCAGGAGATTCCTTTACTGCAG
TCAGTGCCAGAAGTAAATGAGGCCATTACAGGAACTGAAGATGTCAAGCATTACCTCATAAATATTTTACTGAAGAATGCCACAGAAGAA
CCAAATGAATATGCAAGATGCATTGCTGTTTGCTCCCTTGGGGTCTGGATATGTGAAGAGCTTGCACAGTGTACAAGCCACCCTCAGGTG
AAAGAGGCCATCAATGTGATAGGAGTAACTCTGAAGTTTCCCAACAAAATCGTGGCCCAGGTAGCTTGCGATGTCCTTCAGTTGCTGGTT
TCCTACTGGGAGAAGCTTCAGATGTTTGAAACCTCTCTGCCTCGGAAAATGGCAGAAATCCTCGTGGCCACAGTTGCTTTTCTTTTACCA
AGTGCAGAGTACTCCTCAGTGGAAACAGACAAGAAGTTTATTGTGTCCTTGCTACTCTGCCTCTTGGACTGGTGCATGGCATTGCCCGTG
AGTGTCCTTCTCCACCCCGTGTCCACAGCAGTCCTAGAGGAGCAGCATTCGGCCAGAGCCCCCTTGCTGGATTATATCTACAGGGTTTTG
CACTGCTGTGTGTGTGGCTCAAGCACGTACACCCAACAGAGTCACTACATACTGACCCTGGCTGACTTGTCATCCACGGATTATGACCCC
TTCCTGCCACTGGCAAATGTGAAGAGCTCTGAGCCAGTCCAGTATCATTCATCAGCAGAATTGGGTAACCTGCTGACTGTTGAAGAGGAG
AAGAAGAGAAGAAGTTTGGAGTTGATCCCTTTGACTGCTCGAATGGTGATGGCCCACCTGGTGAACCACCTGGGGCACTACCCCCTCAGT
GGGGGCCCTGCCATACTGCACAGCCTTGTCAGCGAGAACCATGACAATGCCCATGTGGAAGGCTCCGAGCTGTCCTTTGAGGTGTTCAGA
AGTCCAAACCTGCAGCTGTTTGTATTTAATGATAGCACCCTCATCTCCTACCTTCAGACACCCACAGAAGGACCGGTAGGGGGATCACCA
GTGGGCTCTCTCTCTGATGTGAGAGTAATTGTGAGGGATATCTCAGGGAAGTACTCTTGGGATGGTAAGGTTTTATATGGACCTTTGGAA
GGCTGCTTAGCACCCAATGGAAGAAATCCTTCATTTCTGATTTCGAGCTGGCATCGTGACACATTTGGACCTCAGAAAGACTCTTCTCAA
GTTGAGGAGGGGGATGATGTTCTTGACAAATTACTTGAAAACATTGGCCATACAAGTCCTGAATGCCTTTTACCGTCACAGCTAAATCTA
AATGAACCTTCCCTAACCCCATGTGGCATGAACTATGACCAAGAGAAGGAAATCATTGAGGTCATTTTGCGCCAAAATGCTCAAGAGGAT
GAGTATATCCAGAGTCATAACTTCGATTCTGCAATGAAAGTCACCAGCCAAGGGCAGCCCTCCCCAGTGGAGCCCCGAGGACCCTTTTAT
TTCTGCAGGTTATTGCTTGATGACTTGGGAATGAATTCTTGGGACAGAAGGAAGAATTTTCATCTATTGAAGAAAAATTCAAAATTATTG
AGAGAGCTGAAAAATTTGGACTCCCGCCAGTGCCGTGAGACACACAAAATCGCAGTGTTTTACATTGCTGAAGGTCAAGAAGACAAGTGT
TCAATCCTCTCTAATGAAAGAGGAAGCCAAGCATATGAAGACTTTGTTGCTGGACTTGGATGGGAGGTGGATCTCTCCACCCACTGTGGG
TTCATGGGTGGCCTTCAGCGCAATGGCAGCACCGGGCAGACGGCCCCTTACTATGCTACCTCAACTGTGGAAGTGATTTTCCATGTTTCC
ACTCGAATGCCGTCAGACTCAGATGATTCCCTCACCAAAAAGCTTCGTCACTTGGGGAATGACGAGGTCCATATCGTCTGGTCTGAACAC
TCCAGAGACTACCGCAGGGGTATTATCCCAACTGCCTTTGGAGATGTTTCAATCATTATTTACCCAATGAAGAATCACATGTTCTTCATC
GCGATAACGAAGAAACCTGAGGTTCCATTTTTTGGGCCTCTGTTTGATGGAGCCATAGTGAGTGGGAAGCTGCTGCCAAGCCTTGTATGT
GCCACGTGCATCAACGCCAGCAGGGCTGTGAAGTGCCTCATCCCACTCTACCAGAGCTTCTATGAAGAGCGAGCTCTGTATCTCGAAGCA
ATAATTCAGAACCACCGCGAAGTAATGACATTCGAGGATTTCGCAGCCCAAGTCTTTTCTCCCTCTCCCAGCTACTCCCTCAGCGGAACG
GATTAAAACACGTAAAGGTCTCATTTCAATATTTGAGCAAGGGGCCCTGGCCTCCAGTCTGAGTGCTGACCTCGAAGAGCCCCTGAGTGA
GGAGGAGACAGAACACCCTCTCCTGCCTCTGCCCCGAGCCACTAAACCCAGAATCTCCAGGAAATTTCGTTGCTGTACTAGTGCCCTCAG
CAGGTCTTCCCATTAGTGGACTTCTGAAGCCCATGGTGAATCCCACTACCGTGTCTCAGATGGGACTCAAACTAGGCTGTATCATCTTGT
CCTGAAACCTCACAAACCTTGGACTTCCAAAGAAGAAAAGAAAAAGTCACCAAAAACCAGAGATGAACCCACTGACACGTGGGCACTGGT
GTGGCTGCTCTGGGCAGATGACAGCAGGAAAAGATTCTGCGCTTTCAGGGAGGGGGCAGAGGGCAGCTTGCTTCTGCACCCCAAGTTGTT

>77240_77240_6_RPRD1A-RALGAPA2_RPRD1A_chr18_33610771_ENST00000588737_RALGAPA2_chr20_20661445_ENST00000202677_length(amino acids)=1809AA_BP=
MENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFAC
LVPGFPAVMSSRGPCTLETLINPSPSVADVKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTL
FRKYYLPHLFPSFTKLTNIYKPVLDIPHLRPKPVYITTTRDNENIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKII
QTVGGGAVQERAPELDGGGPTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRMVYEMVQRILLSTRGYVNFVNEVFHQAFLLPSCEIAVTR
KVVQVYRKWILQDKPVFMEEPDRKDVAQEDAEKLGFSETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEENTNVKAGVQALLQV
FLTNSANIFLLEPCAEVPVLLKEQVDACKAVLIIFRRMIMELTMNKKTWEQMLQILLRITEAVMQKPKDKQIKDLFAQSLAGLLFRTLMV
AWIRANLCVYISRELWDDFLGVLSSLTEWEELINEWANIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDPQKGTTVGRS
FSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEECQQSENAPAAGSGHLTVGQQQQVLRSSSTSDIPEPLCSDSSQGQKA
ENTQNSSSSEPQPIQENKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGKCRERQKSESTNSDTTLGCTNEAELSMGPWQTCEEDPE
LNTPTDVVADADARHWLQLSPTDASNLTDSSECLTDDCSIIAGGSLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFCYLYELWYK
LAKIRDNLAISLDNQSSPSPPVLIPPLRMFASWLFKAATLPNEYKEGKLQAYRLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDI
LNTIIRHCPPRFFSLGFPGFSMLVGDFITAAARVLSTDILTAPRSEAVTVLGSLVCFPNTYQEIPLLQSVPEVNEAITGTEDVKHYLINI
LLKNATEEPNEYARCIAVCSLGVWICEELAQCTSHPQVKEAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETSLPRKMAEILV
ATVAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVSVLLHPVSTAVLEEQHSARAPLLDYIYRVLHCCVCGSSTYTQQSHYILTLAD
LSSTDYDPFLPLANVKSSEPVQYHSSAELGNLLTVEEEKKRRSLELIPLTARMVMAHLVNHLGHYPLSGGPAILHSLVSENHDNAHVEGS
ELSFEVFRSPNLQLFVFNDSTLISYLQTPTEGPVGGSPVGSLSDVRVIVRDISGKYSWDGKVLYGPLEGCLAPNGRNPSFLISSWHRDTF
GPQKDSSQVEEGDDVLDKLLENIGHTSPECLLPSQLNLNEPSLTPCGMNYDQEKEIIEVILRQNAQEDEYIQSHNFDSAMKVTSQGQPSP
VEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWE
VDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYP
MKNHMFFIAITKKPEVPFFGPLFDGAIVSGKLLPSLVCATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for RPRD1A-RALGAPA2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for RPRD1A-RALGAPA2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for RPRD1A-RALGAPA2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource