FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:RPS16-EIF3K (FusionGDB2 ID:77453)

Fusion Gene Summary for RPS16-EIF3K

check button Fusion gene summary
Fusion gene informationFusion gene name: RPS16-EIF3K
Fusion gene ID: 77453
HgeneTgene
Gene symbol

RPS16

EIF3K

Gene ID

6217

27335

Gene nameribosomal protein S16eukaryotic translation initiation factor 3 subunit K
SynonymsS16ARG134|EIF3-p28|EIF3S12|HSPC029|M9|MSTP001|PLAC-24|PLAC24|PRO1474|PTD001
Cytomap

19q13.2

19q13.2

Type of geneprotein-codingprotein-coding
Description40S ribosomal protein S16small ribosomal subunit protein uS9eukaryotic translation initiation factor 3 subunit KeIF-3 p28eukaryotic translation initiation factor 3, subunit 12muscle specificmuscle-specific gene M9 protein
Modification date2020031320200322
UniProtAcc.

Q9UBQ5

Ensembl transtripts involved in fusion geneENST00000251453, ENST00000339471, 
ENST00000599539, ENST00000601655, 
ENST00000538434, ENST00000545173, 
ENST00000588934, ENST00000592558, 
ENST00000593062, ENST00000248342, 
ENST00000593149, 
Fusion gene scores* DoF score22 X 17 X 2=7489 X 11 X 9=891
# samples 2514
** MAII scorelog2(25/748*10)=-1.58111017522555
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/891*10)=-2.66999860457696
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RPS16 [Title/Abstract] AND EIF3K [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRPS16(39926246)-EIF3K(39123069), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneEIF3K

GO:0006413

translational initiation

17581632


check buttonFusion gene breakpoints across RPS16 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EIF3K (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-25-2404RPS16chr19

39926246

-EIF3Kchr19

39123069

+


Top

Fusion Gene ORF analysis for RPS16-EIF3K

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000251453ENST00000538434RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000251453ENST00000545173RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000251453ENST00000588934RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000251453ENST00000592558RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000251453ENST00000593062RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000339471ENST00000538434RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000339471ENST00000545173RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000339471ENST00000588934RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000339471ENST00000592558RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000339471ENST00000593062RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000599539ENST00000538434RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000599539ENST00000545173RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000599539ENST00000588934RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000599539ENST00000592558RPS16chr19

39926246

-EIF3Kchr19

39123069

+
5CDS-intronENST00000599539ENST00000593062RPS16chr19

39926246

-EIF3Kchr19

39123069

+
In-frameENST00000251453ENST00000248342RPS16chr19

39926246

-EIF3Kchr19

39123069

+
In-frameENST00000251453ENST00000593149RPS16chr19

39926246

-EIF3Kchr19

39123069

+
In-frameENST00000339471ENST00000248342RPS16chr19

39926246

-EIF3Kchr19

39123069

+
In-frameENST00000339471ENST00000593149RPS16chr19

39926246

-EIF3Kchr19

39123069

+
In-frameENST00000599539ENST00000248342RPS16chr19

39926246

-EIF3Kchr19

39123069

+
In-frameENST00000599539ENST00000593149RPS16chr19

39926246

-EIF3Kchr19

39123069

+
intron-3CDSENST00000601655ENST00000248342RPS16chr19

39926246

-EIF3Kchr19

39123069

+
intron-3CDSENST00000601655ENST00000593149RPS16chr19

39926246

-EIF3Kchr19

39123069

+
intron-intronENST00000601655ENST00000538434RPS16chr19

39926246

-EIF3Kchr19

39123069

+
intron-intronENST00000601655ENST00000545173RPS16chr19

39926246

-EIF3Kchr19

39123069

+
intron-intronENST00000601655ENST00000588934RPS16chr19

39926246

-EIF3Kchr19

39123069

+
intron-intronENST00000601655ENST00000592558RPS16chr19

39926246

-EIF3Kchr19

39123069

+
intron-intronENST00000601655ENST00000593062RPS16chr19

39926246

-EIF3Kchr19

39123069

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000599539RPS16chr1939926246-ENST00000593149EIF3Kchr1939123069+50617020472150
ENST00000599539RPS16chr1939926246-ENST00000248342EIF3Kchr1939123069+50817020472150
ENST00000339471RPS16chr1939926246-ENST00000593149EIF3Kchr1939123069+52719141493150
ENST00000339471RPS16chr1939926246-ENST00000248342EIF3Kchr1939123069+52919141493150
ENST00000251453RPS16chr1939926246-ENST00000593149EIF3Kchr1939123069+53920353505150
ENST00000251453RPS16chr1939926246-ENST00000248342EIF3Kchr1939123069+54120353505150

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000599539ENST00000593149RPS16chr1939926246-EIF3Kchr1939123069+0.0077155250.9922845
ENST00000599539ENST00000248342RPS16chr1939926246-EIF3Kchr1939123069+0.0079043820.99209565
ENST00000339471ENST00000593149RPS16chr1939926246-EIF3Kchr1939123069+0.0074402760.9925598
ENST00000339471ENST00000248342RPS16chr1939926246-EIF3Kchr1939123069+0.0074232660.99257666
ENST00000251453ENST00000593149RPS16chr1939926246-EIF3Kchr1939123069+0.006340940.9936591
ENST00000251453ENST00000248342RPS16chr1939926246-EIF3Kchr1939123069+0.0063152260.9936847

Top

Fusion Genomic Features for RPS16-EIF3K


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RPS16chr1939926246-EIF3Kchr1939123069+1.59E-070.9999999
RPS16chr1939926246-EIF3Kchr1939123069+1.59E-070.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for RPS16-EIF3K


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:39926246/chr19:39123069)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EIF3K

Q9UBQ5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). {ECO:0000255|HAMAP-Rule:MF_03010, ECO:0000269|PubMed:17581632, ECO:0000269|PubMed:25849773, ECO:0000269|PubMed:27462815}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEIF3Kchr19:39926246chr19:39123069ENST000002483423842_204118219.0DomainPCI


Top

Fusion Gene Sequence for RPS16-EIF3K


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>77453_77453_1_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000251453_EIF3K_chr19_39123069_ENST00000248342_length(transcript)=541nt_BP=203nt
CTTTTCCGGTTGCGGCGCCGCGCGGTGAGGTTGTCTAGTCCACGCTCGGAGCCATGCCGTCCAAGGGCCCGCTGCAGTCTGTGCAGGTCT
TCGGACGCAAGAAGACAGCGACAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTG
AGCCGCGCACGCTACAGTACAAGCAAGCCCTGGATGAAAACATGGACCTCTTGGAAGGTATAACTGGCTTTGAAGACTCTGTCCGAAAGT
TTATCTGCCATGTTGTGGGTATCACTTACCAGCACATTGACCGCTGGCTGCTGGCCGAGATGCTCGGGGATCTGTCGGACAGCCAGCTAA
AGGTGTGGATGAGCAAATACGGCTGGAGTGCCGACGAGTCGGGGCAGATCTTCATCTGTAGCCAAGAAGAGAGCATTAAACCCAAGAACA
TTGTGGAGAAGATTGACTTTGACAGTGTGTCCAGCATCATGGCCTCCTCCCAGTAACTTCAGGTGTTTAATAAAGATGTGTTGACTCAGC

>77453_77453_1_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000251453_EIF3K_chr19_39123069_ENST00000248342_length(amino acids)=150AA_BP=50
MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLL

--------------------------------------------------------------
>77453_77453_2_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000251453_EIF3K_chr19_39123069_ENST00000593149_length(transcript)=539nt_BP=203nt
CTTTTCCGGTTGCGGCGCCGCGCGGTGAGGTTGTCTAGTCCACGCTCGGAGCCATGCCGTCCAAGGGCCCGCTGCAGTCTGTGCAGGTCT
TCGGACGCAAGAAGACAGCGACAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTG
AGCCGCGCACGCTACAGTACAAGCAAGCCCTGGATGAAAACATGGACCTCTTGGAAGGTATAACTGGCTTTGAAGACTCTGTCCGAAAGT
TTATCTGCCATGTTGTGGGTATCACTTACCAGCACATTGACCGCTGGCTGCTGGCCGAGATGCTCGGGGATCTGTCGGACAGCCAGCTAA
AGGTGTGGATGAGCAAATACGGCTGGAGTGCCGACGAGTCGGGGCAGATCTTCATCTGTAGCCAAGAAGAGAGCATTAAACCCAAGAACA

>77453_77453_2_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000251453_EIF3K_chr19_39123069_ENST00000593149_length(amino acids)=150AA_BP=50
MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLL

--------------------------------------------------------------
>77453_77453_3_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000339471_EIF3K_chr19_39123069_ENST00000248342_length(transcript)=529nt_BP=191nt
CGGCGCCGCGCGGTGAGGTTGTCTAGTCCACGCTCGGAGCCATGCCGTCCAAGGGCCCGCTGCAGTCTGTGCAGGTCTTCGGACGCAAGA
AGACAGCGACAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGC
TACAGTACAAGCAAGCCCTGGATGAAAACATGGACCTCTTGGAAGGTATAACTGGCTTTGAAGACTCTGTCCGAAAGTTTATCTGCCATG
TTGTGGGTATCACTTACCAGCACATTGACCGCTGGCTGCTGGCCGAGATGCTCGGGGATCTGTCGGACAGCCAGCTAAAGGTGTGGATGA
GCAAATACGGCTGGAGTGCCGACGAGTCGGGGCAGATCTTCATCTGTAGCCAAGAAGAGAGCATTAAACCCAAGAACATTGTGGAGAAGA

>77453_77453_3_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000339471_EIF3K_chr19_39123069_ENST00000248342_length(amino acids)=150AA_BP=50
MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLL

--------------------------------------------------------------
>77453_77453_4_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000339471_EIF3K_chr19_39123069_ENST00000593149_length(transcript)=527nt_BP=191nt
CGGCGCCGCGCGGTGAGGTTGTCTAGTCCACGCTCGGAGCCATGCCGTCCAAGGGCCCGCTGCAGTCTGTGCAGGTCTTCGGACGCAAGA
AGACAGCGACAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGC
TACAGTACAAGCAAGCCCTGGATGAAAACATGGACCTCTTGGAAGGTATAACTGGCTTTGAAGACTCTGTCCGAAAGTTTATCTGCCATG
TTGTGGGTATCACTTACCAGCACATTGACCGCTGGCTGCTGGCCGAGATGCTCGGGGATCTGTCGGACAGCCAGCTAAAGGTGTGGATGA
GCAAATACGGCTGGAGTGCCGACGAGTCGGGGCAGATCTTCATCTGTAGCCAAGAAGAGAGCATTAAACCCAAGAACATTGTGGAGAAGA

>77453_77453_4_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000339471_EIF3K_chr19_39123069_ENST00000593149_length(amino acids)=150AA_BP=50
MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLL

--------------------------------------------------------------
>77453_77453_5_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000599539_EIF3K_chr19_39123069_ENST00000248342_length(transcript)=508nt_BP=170nt
TCTAGTCCACGCTCGGAGCCATGCCGTCCAAGGGCCCGCTGCAGTCTGTGCAGGTCTTCGGACGCAAGAAGACAGCGACAGCTGTGGCGC
ACTGCAAACGCGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGCTACAGTACAAGCAAGCCCTGG
ATGAAAACATGGACCTCTTGGAAGGTATAACTGGCTTTGAAGACTCTGTCCGAAAGTTTATCTGCCATGTTGTGGGTATCACTTACCAGC
ACATTGACCGCTGGCTGCTGGCCGAGATGCTCGGGGATCTGTCGGACAGCCAGCTAAAGGTGTGGATGAGCAAATACGGCTGGAGTGCCG
ACGAGTCGGGGCAGATCTTCATCTGTAGCCAAGAAGAGAGCATTAAACCCAAGAACATTGTGGAGAAGATTGACTTTGACAGTGTGTCCA

>77453_77453_5_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000599539_EIF3K_chr19_39123069_ENST00000248342_length(amino acids)=150AA_BP=50
MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLL

--------------------------------------------------------------
>77453_77453_6_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000599539_EIF3K_chr19_39123069_ENST00000593149_length(transcript)=506nt_BP=170nt
TCTAGTCCACGCTCGGAGCCATGCCGTCCAAGGGCCCGCTGCAGTCTGTGCAGGTCTTCGGACGCAAGAAGACAGCGACAGCTGTGGCGC
ACTGCAAACGCGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGCTACAGTACAAGCAAGCCCTGG
ATGAAAACATGGACCTCTTGGAAGGTATAACTGGCTTTGAAGACTCTGTCCGAAAGTTTATCTGCCATGTTGTGGGTATCACTTACCAGC
ACATTGACCGCTGGCTGCTGGCCGAGATGCTCGGGGATCTGTCGGACAGCCAGCTAAAGGTGTGGATGAGCAAATACGGCTGGAGTGCCG
ACGAGTCGGGGCAGATCTTCATCTGTAGCCAAGAAGAGAGCATTAAACCCAAGAACATTGTGGAGAAGATTGACTTTGACAGTGTGTCCA

>77453_77453_6_RPS16-EIF3K_RPS16_chr19_39926246_ENST00000599539_EIF3K_chr19_39123069_ENST00000593149_length(amino acids)=150AA_BP=50
MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for RPS16-EIF3K


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for RPS16-EIF3K


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for RPS16-EIF3K


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource