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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RPS27A-PARP9 (FusionGDB2 ID:77749)

Fusion Gene Summary for RPS27A-PARP9

check button Fusion gene summary
Fusion gene informationFusion gene name: RPS27A-PARP9
Fusion gene ID: 77749
HgeneTgene
Gene symbol

RPS27A

PARP9

Gene ID

6233

83666

Gene nameribosomal protein S27apoly(ADP-ribose) polymerase family member 9
SynonymsCEP80|HEL112|S27A|UBA80|UBC|UBCEP1|UBCEP80ARTD9|BAL|BAL1|MGC:7868
Cytomap

2p16.1

3q21.1

Type of geneprotein-codingprotein-coding
Descriptionubiquitin-40S ribosomal protein S27a40S ribosomal protein S27aepididymis luminal protein 112ubiquitin Cubiquitin and ribosomal protein S27aubiquitin carboxyl extension protein 80ubiquitin-CEP80protein mono-ADP-ribosyltransferase PARP9ADP-ribosyltransferase diphtheria toxin-like 9PARP-9b aggressive lymphoma proteinpoly (ADP-ribose) polymerase 9poly [ADP-ribose] polymerase 9
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000272317, ENST00000402285, 
ENST00000404735, 		ENST00000462315, 
ENST00000360356, ENST00000471785, 
ENST00000477522, ENST00000492382, 
Fusion gene scores* DoF score8 X 13 X 6=6244 X 3 X 4=48
# samples 165
** MAII scorelog2(16/624*10)=-1.96347412397489
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/48*10)=0.0588936890535686
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: RPS27A [Title/Abstract] AND PARP9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRPS27A(55462098)-PARP9(122255189), # samples:1
Anticipated loss of major functional domain due to fusion event.RPS27A-PARP9 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePARP9

GO:0006471

protein ADP-ribosylation

28525742

TgenePARP9

GO:0043086

negative regulation of catalytic activity

27796300

TgenePARP9

GO:0060330

regulation of response to interferon-gamma

16809771


check buttonFusion gene breakpoints across RPS27A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PARP9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CG-5719RPS27Achr2

55462098

+PARP9chr3

122255189

-


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Fusion Gene ORF analysis for RPS27A-PARP9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000272317ENST00000462315RPS27Achr2

55462098

+PARP9chr3

122255189

-
Frame-shiftENST00000402285ENST00000462315RPS27Achr2

55462098

+PARP9chr3

122255189

-
Frame-shiftENST00000404735ENST00000462315RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000272317ENST00000360356RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000272317ENST00000471785RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000272317ENST00000477522RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000272317ENST00000492382RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000402285ENST00000360356RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000402285ENST00000471785RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000402285ENST00000477522RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000402285ENST00000492382RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000404735ENST00000360356RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000404735ENST00000471785RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000404735ENST00000477522RPS27Achr2

55462098

+PARP9chr3

122255189

-
In-frameENST00000404735ENST00000492382RPS27Achr2

55462098

+PARP9chr3

122255189

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000402285RPS27Achr255462098+ENST00000477522PARP9chr3122255189-15395441841098304
ENST00000402285RPS27Achr255462098+ENST00000492382PARP9chr3122255189-15045441841098304
ENST00000402285RPS27Achr255462098+ENST00000360356PARP9chr3122255189-15045441841098304
ENST00000402285RPS27Achr255462098+ENST00000471785PARP9chr3122255189-14585441841098304
ENST00000272317RPS27Achr255462098+ENST00000477522PARP9chr3122255189-16406452701199309
ENST00000272317RPS27Achr255462098+ENST00000492382PARP9chr3122255189-16056452701199309
ENST00000272317RPS27Achr255462098+ENST00000360356PARP9chr3122255189-16056452701199309
ENST00000272317RPS27Achr255462098+ENST00000471785PARP9chr3122255189-15596452701199309
ENST00000404735RPS27Achr255462098+ENST00000477522PARP9chr3122255189-14634681471022291
ENST00000404735RPS27Achr255462098+ENST00000492382PARP9chr3122255189-14284681471022291
ENST00000404735RPS27Achr255462098+ENST00000360356PARP9chr3122255189-14284681471022291
ENST00000404735RPS27Achr255462098+ENST00000471785PARP9chr3122255189-13824681471022291

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000402285ENST00000477522RPS27Achr255462098+PARP9chr3122255189-0.0010817340.9989183
ENST00000402285ENST00000492382RPS27Achr255462098+PARP9chr3122255189-0.0012691670.99873084
ENST00000402285ENST00000360356RPS27Achr255462098+PARP9chr3122255189-0.0012691670.99873084
ENST00000402285ENST00000471785RPS27Achr255462098+PARP9chr3122255189-0.0013708130.9986292
ENST00000272317ENST00000477522RPS27Achr255462098+PARP9chr3122255189-0.000512540.9994874
ENST00000272317ENST00000492382RPS27Achr255462098+PARP9chr3122255189-0.0005730220.99942696
ENST00000272317ENST00000360356RPS27Achr255462098+PARP9chr3122255189-0.0005730220.99942696
ENST00000272317ENST00000471785RPS27Achr255462098+PARP9chr3122255189-0.0005916550.99940836
ENST00000404735ENST00000477522RPS27Achr255462098+PARP9chr3122255189-0.0006210380.9993789
ENST00000404735ENST00000492382RPS27Achr255462098+PARP9chr3122255189-0.0006932540.9993068
ENST00000404735ENST00000360356RPS27Achr255462098+PARP9chr3122255189-0.0006932540.9993068
ENST00000404735ENST00000471785RPS27Achr255462098+PARP9chr3122255189-0.0007286690.99927133

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Fusion Genomic Features for RPS27A-PARP9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RPS27A-PARP9


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:55462098/chr3:122255189)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRPS27Achr2:55462098chr3:122255189ENST00000272317+5677_99107157.0Compositional biasNote=Lys-rich (highly basic)
HgeneRPS27Achr2:55462098chr3:122255189ENST00000402285+5677_99107157.0Compositional biasNote=Lys-rich (highly basic)
HgeneRPS27Achr2:55462098chr3:122255189ENST00000404735+4577_99107157.0Compositional biasNote=Lys-rich (highly basic)
HgeneRPS27Achr2:55462098chr3:122255189ENST00000272317+561_76107157.0DomainUbiquitin-like
HgeneRPS27Achr2:55462098chr3:122255189ENST00000402285+561_76107157.0DomainUbiquitin-like
HgeneRPS27Achr2:55462098chr3:122255189ENST00000404735+451_76107157.0DomainUbiquitin-like

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRPS27Achr2:55462098chr3:122255189ENST00000272317+56121_144107157.0Zinc fingerNote=C4-type
HgeneRPS27Achr2:55462098chr3:122255189ENST00000402285+56121_144107157.0Zinc fingerNote=C4-type
HgeneRPS27Achr2:55462098chr3:122255189ENST00000404735+45121_144107157.0Zinc fingerNote=C4-type
TgenePARP9chr2:55462098chr3:122255189ENST00000360356811107_296670855.0DomainMacro 1
TgenePARP9chr2:55462098chr3:122255189ENST00000360356811306_487670855.0DomainMacro 2
TgenePARP9chr2:55462098chr3:122255189ENST00000360356811628_850670855.0DomainPARP catalytic
TgenePARP9chr2:55462098chr3:122255189ENST00000462315810107_296635711.0DomainMacro 1
TgenePARP9chr2:55462098chr3:122255189ENST00000462315810306_487635711.0DomainMacro 2
TgenePARP9chr2:55462098chr3:122255189ENST00000462315810628_850635711.0DomainPARP catalytic
TgenePARP9chr2:55462098chr3:122255189ENST00000471785811107_296635820.0DomainMacro 1
TgenePARP9chr2:55462098chr3:122255189ENST00000471785811306_487635820.0DomainMacro 2
TgenePARP9chr2:55462098chr3:122255189ENST00000471785811628_850635820.0DomainPARP catalytic
TgenePARP9chr2:55462098chr3:122255189ENST00000477522811107_296635820.0DomainMacro 1
TgenePARP9chr2:55462098chr3:122255189ENST00000477522811306_487635820.0DomainMacro 2
TgenePARP9chr2:55462098chr3:122255189ENST00000477522811628_850635820.0DomainPARP catalytic


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Fusion Gene Sequence for RPS27A-PARP9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>77749_77749_1_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000272317_PARP9_chr3_122255189_ENST00000360356_length(transcript)=1605nt_BP=645nt
CCCCTCGACCTCCTTTTAAAAATTCTCTTAGCCACGTTGATTGTACGGGAAAAGCCTTTTTAAAACATCTTTTACGTTGCTTAAACCTAC
AGTTTCGAAAGCATTCCGAAGGCTAAAGTGAGAAATAAGCCCAGGCTAGGGAGAGGAGAAACGAAGTTCACGTCCTAGTCTGGCACCGGG
TTGGATTGTCGCTGGGACGGCAGTCAGGCATTTGGTGTGGTCGCCTAAGGGGTGGGTCCTTCGGCGGGAGCTCCGGGAAACCCCGTGGGC
CTGCGCGGCGTTCTTCCTTTTCGATCCGCCATCTGCGGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAGACC
ATCACCCTCGAGGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAGAGA
CTGATCTTTGCTGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTGAGA
CTTCGTGGTGGTGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCTGTC
CTGAAATATTATAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTGCAC
AGGCAACCTGTGAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTACTCG
ACACCTTGCGATCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCTGCA
GATAAGCTGATCTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTGAGT
CCTGGAGCTATAGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATACCT
CAGTATTTGTGGACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGGAGG
GGATTCGCAAGTGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAATGA
CCATCGATGGCTCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATACTAG
CATCTTAGTGCCTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTTGCA
GTTGTTCTTTAATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTATTTT

>77749_77749_1_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000272317_PARP9_chr3_122255189_ENST00000360356_length(amino acids)=309AA_BP=125
MRGVLPFRSAICGGAATKMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLR
LRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYS
TPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIP

--------------------------------------------------------------
>77749_77749_2_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000272317_PARP9_chr3_122255189_ENST00000471785_length(transcript)=1559nt_BP=645nt
CCCCTCGACCTCCTTTTAAAAATTCTCTTAGCCACGTTGATTGTACGGGAAAAGCCTTTTTAAAACATCTTTTACGTTGCTTAAACCTAC
AGTTTCGAAAGCATTCCGAAGGCTAAAGTGAGAAATAAGCCCAGGCTAGGGAGAGGAGAAACGAAGTTCACGTCCTAGTCTGGCACCGGG
TTGGATTGTCGCTGGGACGGCAGTCAGGCATTTGGTGTGGTCGCCTAAGGGGTGGGTCCTTCGGCGGGAGCTCCGGGAAACCCCGTGGGC
CTGCGCGGCGTTCTTCCTTTTCGATCCGCCATCTGCGGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAGACC
ATCACCCTCGAGGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAGAGA
CTGATCTTTGCTGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTGAGA
CTTCGTGGTGGTGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCTGTC
CTGAAATATTATAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTGCAC
AGGCAACCTGTGAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTACTCG
ACACCTTGCGATCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCTGCA
GATAAGCTGATCTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTGAGT
CCTGGAGCTATAGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATACCT
CAGTATTTGTGGACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGGAGG
GGATTCGCAAGTGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAATGA
CCATCGATGGCTCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATACTAG
CATCTTAGTGCCTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTTGCA
GTTGTTCTTTAATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTATTTT

>77749_77749_2_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000272317_PARP9_chr3_122255189_ENST00000471785_length(amino acids)=309AA_BP=125
MRGVLPFRSAICGGAATKMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLR
LRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYS
TPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIP

--------------------------------------------------------------
>77749_77749_3_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000272317_PARP9_chr3_122255189_ENST00000477522_length(transcript)=1640nt_BP=645nt
CCCCTCGACCTCCTTTTAAAAATTCTCTTAGCCACGTTGATTGTACGGGAAAAGCCTTTTTAAAACATCTTTTACGTTGCTTAAACCTAC
AGTTTCGAAAGCATTCCGAAGGCTAAAGTGAGAAATAAGCCCAGGCTAGGGAGAGGAGAAACGAAGTTCACGTCCTAGTCTGGCACCGGG
TTGGATTGTCGCTGGGACGGCAGTCAGGCATTTGGTGTGGTCGCCTAAGGGGTGGGTCCTTCGGCGGGAGCTCCGGGAAACCCCGTGGGC
CTGCGCGGCGTTCTTCCTTTTCGATCCGCCATCTGCGGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAGACC
ATCACCCTCGAGGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAGAGA
CTGATCTTTGCTGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTGAGA
CTTCGTGGTGGTGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCTGTC
CTGAAATATTATAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTGCAC
AGGCAACCTGTGAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTACTCG
ACACCTTGCGATCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCTGCA
GATAAGCTGATCTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTGAGT
CCTGGAGCTATAGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATACCT
CAGTATTTGTGGACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGGAGG
GGATTCGCAAGTGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAATGA
CCATCGATGGCTCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATACTAG
CATCTTAGTGCCTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTTGCA
GTTGTTCTTTAATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTATTTT
CTAAAATGATGATAGTATAAAAATGTTAGGATAACAGAATGATTTTAGATTTTCCAGAGAATATTATAAAGTGCTTTAGGTATGAAAATA

>77749_77749_3_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000272317_PARP9_chr3_122255189_ENST00000477522_length(amino acids)=309AA_BP=125
MRGVLPFRSAICGGAATKMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLR
LRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYS
TPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIP

--------------------------------------------------------------
>77749_77749_4_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000272317_PARP9_chr3_122255189_ENST00000492382_length(transcript)=1605nt_BP=645nt
CCCCTCGACCTCCTTTTAAAAATTCTCTTAGCCACGTTGATTGTACGGGAAAAGCCTTTTTAAAACATCTTTTACGTTGCTTAAACCTAC
AGTTTCGAAAGCATTCCGAAGGCTAAAGTGAGAAATAAGCCCAGGCTAGGGAGAGGAGAAACGAAGTTCACGTCCTAGTCTGGCACCGGG
TTGGATTGTCGCTGGGACGGCAGTCAGGCATTTGGTGTGGTCGCCTAAGGGGTGGGTCCTTCGGCGGGAGCTCCGGGAAACCCCGTGGGC
CTGCGCGGCGTTCTTCCTTTTCGATCCGCCATCTGCGGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAGACC
ATCACCCTCGAGGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAGAGA
CTGATCTTTGCTGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTGAGA
CTTCGTGGTGGTGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCTGTC
CTGAAATATTATAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTGCAC
AGGCAACCTGTGAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTACTCG
ACACCTTGCGATCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCTGCA
GATAAGCTGATCTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTGAGT
CCTGGAGCTATAGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATACCT
CAGTATTTGTGGACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGGAGG
GGATTCGCAAGTGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAATGA
CCATCGATGGCTCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATACTAG
CATCTTAGTGCCTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTTGCA
GTTGTTCTTTAATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTATTTT

>77749_77749_4_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000272317_PARP9_chr3_122255189_ENST00000492382_length(amino acids)=309AA_BP=125
MRGVLPFRSAICGGAATKMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLR
LRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYS
TPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIP

--------------------------------------------------------------
>77749_77749_5_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000402285_PARP9_chr3_122255189_ENST00000360356_length(transcript)=1504nt_BP=544nt
AAGACCCAGACTCTTCCCTAGGCTGGGAGAGACTCGGCGGTTGAAAGCAGGGAGGCGCTACAGGAGAGAAAGGGCTGAACCCCCGCTTCC
GCAGATTTCACCTATTTTTCAGTTTGCCTGGAGCAGGCCACGCAAATTCCCTTCCCTTGAAGGCCCAAGGAGCGTCTGGTAGATTGCTGA
TTCTCTGCCCATCACCGCTTCTGGAAGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAGACCATCACCCTCGA
GGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAGAGACTGATCTTTGC
TGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTGAGACTTCGTGGTGG
TGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCTGTCCTGAAATATTA
TAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTGCACAGGCAACCTGT
GAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTACTCGACACCTTGCGA
TCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCTGCAGATAAGCTGAT
CTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTGAGTCCTGGAGCTAT
AGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATACCTCAGTATTTGTG
GACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGGAGGGGATTCGCAAG
TGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAATGACCATCGATGGC
TCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATACTAGCATCTTAGTGC
CTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTTGCAGTTGTTCTTTA
ATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTATTTTCTAAAATGATG

>77749_77749_5_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000402285_PARP9_chr3_122255189_ENST00000360356_length(amino acids)=304AA_BP=120
MPITASGSGAATKMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGA
KKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCDP
KYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWT

--------------------------------------------------------------
>77749_77749_6_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000402285_PARP9_chr3_122255189_ENST00000471785_length(transcript)=1458nt_BP=544nt
AAGACCCAGACTCTTCCCTAGGCTGGGAGAGACTCGGCGGTTGAAAGCAGGGAGGCGCTACAGGAGAGAAAGGGCTGAACCCCCGCTTCC
GCAGATTTCACCTATTTTTCAGTTTGCCTGGAGCAGGCCACGCAAATTCCCTTCCCTTGAAGGCCCAAGGAGCGTCTGGTAGATTGCTGA
TTCTCTGCCCATCACCGCTTCTGGAAGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAGACCATCACCCTCGA
GGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAGAGACTGATCTTTGC
TGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTGAGACTTCGTGGTGG
TGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCTGTCCTGAAATATTA
TAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTGCACAGGCAACCTGT
GAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTACTCGACACCTTGCGA
TCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCTGCAGATAAGCTGAT
CTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTGAGTCCTGGAGCTAT
AGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATACCTCAGTATTTGTG
GACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGGAGGGGATTCGCAAG
TGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAATGACCATCGATGGC
TCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATACTAGCATCTTAGTGC
CTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTTGCAGTTGTTCTTTA
ATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTATTTTCTAAAATGATG

>77749_77749_6_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000402285_PARP9_chr3_122255189_ENST00000471785_length(amino acids)=304AA_BP=120
MPITASGSGAATKMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGA
KKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCDP
KYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWT

--------------------------------------------------------------
>77749_77749_7_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000402285_PARP9_chr3_122255189_ENST00000477522_length(transcript)=1539nt_BP=544nt
AAGACCCAGACTCTTCCCTAGGCTGGGAGAGACTCGGCGGTTGAAAGCAGGGAGGCGCTACAGGAGAGAAAGGGCTGAACCCCCGCTTCC
GCAGATTTCACCTATTTTTCAGTTTGCCTGGAGCAGGCCACGCAAATTCCCTTCCCTTGAAGGCCCAAGGAGCGTCTGGTAGATTGCTGA
TTCTCTGCCCATCACCGCTTCTGGAAGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAGACCATCACCCTCGA
GGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAGAGACTGATCTTTGC
TGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTGAGACTTCGTGGTGG
TGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCTGTCCTGAAATATTA
TAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTGCACAGGCAACCTGT
GAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTACTCGACACCTTGCGA
TCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCTGCAGATAAGCTGAT
CTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTGAGTCCTGGAGCTAT
AGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATACCTCAGTATTTGTG
GACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGGAGGGGATTCGCAAG
TGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAATGACCATCGATGGC
TCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATACTAGCATCTTAGTGC
CTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTTGCAGTTGTTCTTTA
ATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTATTTTCTAAAATGATG
ATAGTATAAAAATGTTAGGATAACAGAATGATTTTAGATTTTCCAGAGAATATTATAAAGTGCTTTAGGTATGAAAATAAATCATCTTTG

>77749_77749_7_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000402285_PARP9_chr3_122255189_ENST00000477522_length(amino acids)=304AA_BP=120
MPITASGSGAATKMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGA
KKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCDP
KYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWT

--------------------------------------------------------------
>77749_77749_8_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000402285_PARP9_chr3_122255189_ENST00000492382_length(transcript)=1504nt_BP=544nt
AAGACCCAGACTCTTCCCTAGGCTGGGAGAGACTCGGCGGTTGAAAGCAGGGAGGCGCTACAGGAGAGAAAGGGCTGAACCCCCGCTTCC
GCAGATTTCACCTATTTTTCAGTTTGCCTGGAGCAGGCCACGCAAATTCCCTTCCCTTGAAGGCCCAAGGAGCGTCTGGTAGATTGCTGA
TTCTCTGCCCATCACCGCTTCTGGAAGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAGACCATCACCCTCGA
GGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAGAGACTGATCTTTGC
TGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTGAGACTTCGTGGTGG
TGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCTGTCCTGAAATATTA
TAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTGCACAGGCAACCTGT
GAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTACTCGACACCTTGCGA
TCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCTGCAGATAAGCTGAT
CTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTGAGTCCTGGAGCTAT
AGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATACCTCAGTATTTGTG
GACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGGAGGGGATTCGCAAG
TGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAATGACCATCGATGGC
TCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATACTAGCATCTTAGTGC
CTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTTGCAGTTGTTCTTTA
ATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTATTTTCTAAAATGATG

>77749_77749_8_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000402285_PARP9_chr3_122255189_ENST00000492382_length(amino acids)=304AA_BP=120
MPITASGSGAATKMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGA
KKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCDP
KYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWT

--------------------------------------------------------------
>77749_77749_9_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000404735_PARP9_chr3_122255189_ENST00000360356_length(transcript)=1428nt_BP=468nt
GGCGTTCTTCCTTTTCGATCCGCCATCTGCGGTGGGTGTCTGCACTTCGGCTGCTCTCGGGTTAGCACCCTATGGTGCCTTCTCTTGTGA
TCCCTGACCTAACCTGTCTCTTCCTTTTCCTCAACCTCAGGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAG
ACCATCACCCTCGAGGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAG
AGACTGATCTTTGCTGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTG
AGACTTCGTGGTGGTGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCT
GTCCTGAAATATTATAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTG
CACAGGCAACCTGTGAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTAC
TCGACACCTTGCGATCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCT
GCAGATAAGCTGATCTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTG
AGTCCTGGAGCTATAGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATA
CCTCAGTATTTGTGGACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGG
AGGGGATTCGCAAGTGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAA
TGACCATCGATGGCTCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATAC
TAGCATCTTAGTGCCTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTT
GCAGTTGTTCTTTAATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTAT

>77749_77749_9_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000404735_PARP9_chr3_122255189_ENST00000360356_length(amino acids)=291AA_BP=107
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKK
NKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCDPKYGAGIYFTKNLK
NLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQEYVQSQDYSS

--------------------------------------------------------------
>77749_77749_10_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000404735_PARP9_chr3_122255189_ENST00000471785_length(transcript)=1382nt_BP=468nt
GGCGTTCTTCCTTTTCGATCCGCCATCTGCGGTGGGTGTCTGCACTTCGGCTGCTCTCGGGTTAGCACCCTATGGTGCCTTCTCTTGTGA
TCCCTGACCTAACCTGTCTCTTCCTTTTCCTCAACCTCAGGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAG
ACCATCACCCTCGAGGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAG
AGACTGATCTTTGCTGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTG
AGACTTCGTGGTGGTGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCT
GTCCTGAAATATTATAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTG
CACAGGCAACCTGTGAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTAC
TCGACACCTTGCGATCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCT
GCAGATAAGCTGATCTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTG
AGTCCTGGAGCTATAGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATA
CCTCAGTATTTGTGGACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGG
AGGGGATTCGCAAGTGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAA
TGACCATCGATGGCTCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATAC
TAGCATCTTAGTGCCTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTT
GCAGTTGTTCTTTAATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTAT

>77749_77749_10_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000404735_PARP9_chr3_122255189_ENST00000471785_length(amino acids)=291AA_BP=107
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKK
NKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCDPKYGAGIYFTKNLK
NLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQEYVQSQDYSS

--------------------------------------------------------------
>77749_77749_11_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000404735_PARP9_chr3_122255189_ENST00000477522_length(transcript)=1463nt_BP=468nt
GGCGTTCTTCCTTTTCGATCCGCCATCTGCGGTGGGTGTCTGCACTTCGGCTGCTCTCGGGTTAGCACCCTATGGTGCCTTCTCTTGTGA
TCCCTGACCTAACCTGTCTCTTCCTTTTCCTCAACCTCAGGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAG
ACCATCACCCTCGAGGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAG
AGACTGATCTTTGCTGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTG
AGACTTCGTGGTGGTGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCT
GTCCTGAAATATTATAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTG
CACAGGCAACCTGTGAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTAC
TCGACACCTTGCGATCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCT
GCAGATAAGCTGATCTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTG
AGTCCTGGAGCTATAGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATA
CCTCAGTATTTGTGGACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGG
AGGGGATTCGCAAGTGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAA
TGACCATCGATGGCTCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATAC
TAGCATCTTAGTGCCTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTT
GCAGTTGTTCTTTAATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTAT
TTTCTAAAATGATGATAGTATAAAAATGTTAGGATAACAGAATGATTTTAGATTTTCCAGAGAATATTATAAAGTGCTTTAGGTATGAAA

>77749_77749_11_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000404735_PARP9_chr3_122255189_ENST00000477522_length(amino acids)=291AA_BP=107
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKK
NKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCDPKYGAGIYFTKNLK
NLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQEYVQSQDYSS

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>77749_77749_12_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000404735_PARP9_chr3_122255189_ENST00000492382_length(transcript)=1428nt_BP=468nt
GGCGTTCTTCCTTTTCGATCCGCCATCTGCGGTGGGTGTCTGCACTTCGGCTGCTCTCGGGTTAGCACCCTATGGTGCCTTCTCTTGTGA
TCCCTGACCTAACCTGTCTCTTCCTTTTCCTCAACCTCAGGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAG
ACCATCACCCTCGAGGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAG
AGACTGATCTTTGCTGGCAAGCAGCTGGAAGATGGACGTACTTTGTCTGACTACAATATTCAAAAGGAGTCTACTCTTCATCTTGTGTTG
AGACTTCGTGGTGGTGCTAAGAAAAGGAAGAAGAAGTCTTACACCACTCCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCT
GTCCTGAAATATTATAAGGTGGAGAAGATAGACAATGAGGTCCTTATGGCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTG
CACAGGCAACCTGTGAGCCATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTTCAAAGAATGTAC
TCGACACCTTGCGATCCAAAATACGGAGCTGGCATATACTTCACCAAGAACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCT
GCAGATAAGCTGATCTATGTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTTCCCCCACCACTG
AGTCCTGGAGCTATAGATGGTCATGACAGTGTGGTTGACAATGTCTCCAGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATA
CCTCAGTATTTGTGGACATGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCACAGCATCCTTGG
AGGGGATTCGCAAGTGGCAGCCCTGTTGATTAATCTCTACATCATTTTAACAGCTGGTATGGCCTTACCTTGGGTGAACTAACCAAATAA
TGACCATCGATGGCTCAAAGAGTGGCTTGAATATATCCCATGGGTTATCTGTATGGACTGACTGGGTTATTGAAAGGACTAGCCACATAC
TAGCATCTTAGTGCCTTTATCTGTCTTTATGTCTTGGGGTTGGGGTAGGTAGATACCAAATGAAACACTTTCAGGACCTTCCTTCCTCTT
GCAGTTGTTCTTTAATCTCCTTTACTAGAGGAGATAAATATTTTGCATATAATGAAGAAATTTTTCTAGTATATAACGCAGGCCTTTTAT

>77749_77749_12_RPS27A-PARP9_RPS27A_chr2_55462098_ENST00000404735_PARP9_chr3_122255189_ENST00000492382_length(amino acids)=291AA_BP=107
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKK
NKHKRKKVKLAVLKYYKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCDPKYGAGIYFTKNLK
NLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQEYVQSQDYSS

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Fusion Gene PPI Analysis for RPS27A-PARP9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RPS27A-PARP9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RPS27A-PARP9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource