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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RPS6KA1-RASGRP3 (FusionGDB2 ID:77986)

Fusion Gene Summary for RPS6KA1-RASGRP3

check button Fusion gene summary
Fusion gene informationFusion gene name: RPS6KA1-RASGRP3
Fusion gene ID: 77986
HgeneTgene
Gene symbol

RPS6KA1

RASGRP3

Gene ID

6195

25780

Gene nameribosomal protein S6 kinase A1RAS guanyl releasing protein 3
SynonymsHU-1|MAPKAPK1|MAPKAPK1A|RSK|RSK1|p90RskGRP3
Cytomap

1p36.11

2p22.3

Type of geneprotein-codingprotein-coding
Descriptionribosomal protein S6 kinase alpha-190 kDa ribosomal protein S6 kinase 1MAP kinase-activated protein kinase 1aMAPK-activated protein kinase 1aMAPKAP kinase 1aMAPKAPK-1aRSK-1S6K-alpha 1dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1)p9ras guanyl-releasing protein 3CalDAG-GEFIIIRAS guanyl releasing protein 3 (calcium and DAG-regulated)calcium and DAG-regulated guanine nucleotide exchange factor IIIcalcium- and diacylglycerol-regulated guanine nucleotide exchange factor IIIguanine n
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000374166, ENST00000374168, 
ENST00000374162, ENST00000526792, 
ENST00000488985, ENST00000530003, 
ENST00000531382, 		ENST00000482731, 
ENST00000402538, ENST00000403687, 
ENST00000407811, 
Fusion gene scores* DoF score3 X 4 X 3=363 X 4 X 3=36
# samples 54
** MAII scorelog2(5/36*10)=0.473931188332412
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: RPS6KA1 [Title/Abstract] AND RASGRP3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRPS6KA1(26863460)-RASGRP3(33759390), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRPS6KA1

GO:0043154

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

18402937


check buttonFusion gene breakpoints across RPS6KA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RASGRP3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A106-01ARPS6KA1chr1

26863460

-RASGRP3chr2

33759390

+
ChimerDB4BRCATCGA-E2-A106-01ARPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
ChimerDB4BRCATCGA-E2-A106RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+


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Fusion Gene ORF analysis for RPS6KA1-RASGRP3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000374166ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
5CDS-intronENST00000374166ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
5CDS-intronENST00000374168ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
5CDS-intronENST00000374168ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
5UTR-3CDSENST00000374162ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
5UTR-3CDSENST00000374162ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
5UTR-3CDSENST00000374162ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
5UTR-3CDSENST00000374162ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
5UTR-3CDSENST00000374162ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
5UTR-3CDSENST00000374162ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
5UTR-3CDSENST00000526792ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
5UTR-3CDSENST00000526792ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
5UTR-3CDSENST00000526792ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
5UTR-3CDSENST00000526792ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
5UTR-3CDSENST00000526792ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
5UTR-3CDSENST00000526792ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
5UTR-intronENST00000374162ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
5UTR-intronENST00000374162ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
5UTR-intronENST00000526792ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
5UTR-intronENST00000526792ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
In-frameENST00000374166ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
In-frameENST00000374166ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
In-frameENST00000374166ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
In-frameENST00000374166ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
In-frameENST00000374166ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
In-frameENST00000374166ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
In-frameENST00000374168ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
In-frameENST00000374168ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
In-frameENST00000374168ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
In-frameENST00000374168ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
In-frameENST00000374168ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
In-frameENST00000374168ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-3CDSENST00000488985ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-3CDSENST00000488985ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-3CDSENST00000488985ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-3CDSENST00000488985ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-3CDSENST00000488985ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-3CDSENST00000488985ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-3CDSENST00000530003ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-3CDSENST00000530003ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-3CDSENST00000530003ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-3CDSENST00000530003ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-3CDSENST00000530003ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-3CDSENST00000530003ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-3CDSENST00000531382ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-3CDSENST00000531382ENST00000402538RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-3CDSENST00000531382ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-3CDSENST00000531382ENST00000403687RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-3CDSENST00000531382ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-3CDSENST00000531382ENST00000407811RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-intronENST00000488985ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-intronENST00000488985ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-intronENST00000530003ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-intronENST00000530003ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+
intron-intronENST00000531382ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759390

+
intron-intronENST00000531382ENST00000482731RPS6KA1chr1

26863460

+RASGRP3chr2

33759389

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000374168RPS6KA1chr126863460+ENST00000402538RASGRP3chr233759390+32652621541251365
ENST00000374168RPS6KA1chr126863460+ENST00000403687RASGRP3chr233759390+32462621541251365
ENST00000374168RPS6KA1chr126863460+ENST00000407811RASGRP3chr233759390+31172621541248364
ENST00000374166RPS6KA1chr126863460+ENST00000402538RASGRP3chr233759390+32542511431240365
ENST00000374166RPS6KA1chr126863460+ENST00000403687RASGRP3chr233759390+32352511431240365
ENST00000374166RPS6KA1chr126863460+ENST00000407811RASGRP3chr233759390+31062511431237364
ENST00000374168RPS6KA1chr126863460+ENST00000402538RASGRP3chr233759389+32652621541251365
ENST00000374168RPS6KA1chr126863460+ENST00000403687RASGRP3chr233759389+32462621541251365
ENST00000374168RPS6KA1chr126863460+ENST00000407811RASGRP3chr233759389+31172621541248364
ENST00000374166RPS6KA1chr126863460+ENST00000402538RASGRP3chr233759389+32542511431240365
ENST00000374166RPS6KA1chr126863460+ENST00000403687RASGRP3chr233759389+32352511431240365
ENST00000374166RPS6KA1chr126863460+ENST00000407811RASGRP3chr233759389+31062511431237364

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000374168ENST00000402538RPS6KA1chr126863460+RASGRP3chr233759390+0.0003185030.9996815
ENST00000374168ENST00000403687RPS6KA1chr126863460+RASGRP3chr233759390+0.0003307860.9996692
ENST00000374168ENST00000407811RPS6KA1chr126863460+RASGRP3chr233759390+0.0004654590.9995346
ENST00000374166ENST00000402538RPS6KA1chr126863460+RASGRP3chr233759390+0.0003191020.9996809
ENST00000374166ENST00000403687RPS6KA1chr126863460+RASGRP3chr233759390+0.0003322250.99966776
ENST00000374166ENST00000407811RPS6KA1chr126863460+RASGRP3chr233759390+0.0004680950.99953187
ENST00000374168ENST00000402538RPS6KA1chr126863460+RASGRP3chr233759389+0.0003185030.9996815
ENST00000374168ENST00000403687RPS6KA1chr126863460+RASGRP3chr233759389+0.0003307860.9996692
ENST00000374168ENST00000407811RPS6KA1chr126863460+RASGRP3chr233759389+0.0004654590.9995346
ENST00000374166ENST00000402538RPS6KA1chr126863460+RASGRP3chr233759389+0.0003191020.9996809
ENST00000374166ENST00000403687RPS6KA1chr126863460+RASGRP3chr233759389+0.0003322250.99966776
ENST00000374166ENST00000407811RPS6KA1chr126863460+RASGRP3chr233759389+0.0004680950.99953187

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Fusion Genomic Features for RPS6KA1-RASGRP3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RPS6KA1chr126863460+RASGRP3chr233759389+0.0001400780.9998599
RPS6KA1chr126863460+RASGRP3chr233759389+0.0001400780.9998599
RPS6KA1chr126863460+RASGRP3chr233759389+0.0001400780.9998599
RPS6KA1chr126863460+RASGRP3chr233759389+0.0001400780.9998599

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for RPS6KA1-RASGRP3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:26863460/chr2:33759390)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRASGRP3chr1:26863460chr2:33759389ENST000004025381019433_444361691.0Calcium binding1
TgeneRASGRP3chr1:26863460chr2:33759389ENST000004025381019462_473361691.0Calcium binding2
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000403687918433_444361691.0Calcium binding1
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000403687918462_473361691.0Calcium binding2
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000407811817433_444361690.0Calcium binding1
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000407811817462_473361690.0Calcium binding2
TgeneRASGRP3chr1:26863460chr2:33759390ENST000004025381019433_444361691.0Calcium binding1
TgeneRASGRP3chr1:26863460chr2:33759390ENST000004025381019462_473361691.0Calcium binding2
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000403687918433_444361691.0Calcium binding1
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000403687918462_473361691.0Calcium binding2
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000407811817433_444361690.0Calcium binding1
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000407811817462_473361690.0Calcium binding2
TgeneRASGRP3chr1:26863460chr2:33759389ENST000004025381019420_455361691.0DomainEF-hand 1
TgeneRASGRP3chr1:26863460chr2:33759389ENST000004025381019449_484361691.0DomainEF-hand 2
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000403687918420_455361691.0DomainEF-hand 1
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000403687918449_484361691.0DomainEF-hand 2
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000407811817420_455361690.0DomainEF-hand 1
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000407811817449_484361690.0DomainEF-hand 2
TgeneRASGRP3chr1:26863460chr2:33759390ENST000004025381019420_455361691.0DomainEF-hand 1
TgeneRASGRP3chr1:26863460chr2:33759390ENST000004025381019449_484361691.0DomainEF-hand 2
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000403687918420_455361691.0DomainEF-hand 1
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000403687918449_484361691.0DomainEF-hand 2
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000407811817420_455361690.0DomainEF-hand 1
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000407811817449_484361690.0DomainEF-hand 2
TgeneRASGRP3chr1:26863460chr2:33759389ENST000004025381019494_544361691.0Zinc fingerPhorbol-ester/DAG-type
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000403687918494_544361691.0Zinc fingerPhorbol-ester/DAG-type
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000407811817494_544361690.0Zinc fingerPhorbol-ester/DAG-type
TgeneRASGRP3chr1:26863460chr2:33759390ENST000004025381019494_544361691.0Zinc fingerPhorbol-ester/DAG-type
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000403687918494_544361691.0Zinc fingerPhorbol-ester/DAG-type
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000407811817494_544361690.0Zinc fingerPhorbol-ester/DAG-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000374162+221322_3910644.0DomainAGC-kinase C-terminal
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000374162+221418_6750644.0DomainProtein kinase 2
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000374162+22162_3210644.0DomainProtein kinase 1
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000374168+222322_39136736.0DomainAGC-kinase C-terminal
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000374168+222418_67536736.0DomainProtein kinase 2
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000374168+22262_32136736.0DomainProtein kinase 1
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000526792+222322_3910644.0DomainAGC-kinase C-terminal
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000526792+222418_6750644.0DomainProtein kinase 2
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000526792+22262_3210644.0DomainProtein kinase 1
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000531382+121322_3910745.0DomainAGC-kinase C-terminal
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000531382+121418_6750745.0DomainProtein kinase 2
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000531382+12162_3210745.0DomainProtein kinase 1
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000374162+221322_3910644.0DomainAGC-kinase C-terminal
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000374162+221418_6750644.0DomainProtein kinase 2
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000374162+22162_3210644.0DomainProtein kinase 1
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000374168+222322_39136736.0DomainAGC-kinase C-terminal
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000374168+222418_67536736.0DomainProtein kinase 2
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000374168+22262_32136736.0DomainProtein kinase 1
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000526792+222322_3910644.0DomainAGC-kinase C-terminal
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000526792+222418_6750644.0DomainProtein kinase 2
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000526792+22262_3210644.0DomainProtein kinase 1
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000531382+121322_3910745.0DomainAGC-kinase C-terminal
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000531382+121418_6750745.0DomainProtein kinase 2
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000531382+12162_3210745.0DomainProtein kinase 1
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000374162+221424_4320644.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000374162+22168_760644.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000374168+222424_43236736.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000374168+22268_7636736.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000526792+222424_4320644.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000526792+22268_760644.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000531382+121424_4320745.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759389ENST00000531382+12168_760745.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000374162+221424_4320644.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000374162+22168_760644.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000374168+222424_43236736.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000374168+22268_7636736.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000526792+222424_4320644.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000526792+22268_760644.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000531382+121424_4320745.0Nucleotide bindingATP
HgeneRPS6KA1chr1:26863460chr2:33759390ENST00000531382+12168_760745.0Nucleotide bindingATP
TgeneRASGRP3chr1:26863460chr2:33759389ENST000004025381019152_383361691.0DomainRas-GEF
TgeneRASGRP3chr1:26863460chr2:33759389ENST0000040253810193_125361691.0DomainN-terminal Ras-GEF
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000403687918152_383361691.0DomainRas-GEF
TgeneRASGRP3chr1:26863460chr2:33759389ENST000004036879183_125361691.0DomainN-terminal Ras-GEF
TgeneRASGRP3chr1:26863460chr2:33759389ENST00000407811817152_383361690.0DomainRas-GEF
TgeneRASGRP3chr1:26863460chr2:33759389ENST000004078118173_125361690.0DomainN-terminal Ras-GEF
TgeneRASGRP3chr1:26863460chr2:33759390ENST000004025381019152_383361691.0DomainRas-GEF
TgeneRASGRP3chr1:26863460chr2:33759390ENST0000040253810193_125361691.0DomainN-terminal Ras-GEF
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000403687918152_383361691.0DomainRas-GEF
TgeneRASGRP3chr1:26863460chr2:33759390ENST000004036879183_125361691.0DomainN-terminal Ras-GEF
TgeneRASGRP3chr1:26863460chr2:33759390ENST00000407811817152_383361690.0DomainRas-GEF
TgeneRASGRP3chr1:26863460chr2:33759390ENST000004078118173_125361690.0DomainN-terminal Ras-GEF


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Fusion Gene Sequence for RPS6KA1-RASGRP3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>77986_77986_1_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759389_ENST00000402538_length(transcript)=3254nt_BP=251nt
GCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCCCAGGACCCGGG
AGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCCCTGGCCGCTCA
TGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCTGGACCTCTATC
ACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCAGCCTACCTCCCCTACGACGCCCAACAAGC
CTGTGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATTAGTGGAGTCTG
TATTTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTTCTTGGATTCCT
TCTGTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCAACTACACTGTA
AAATGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATTTCTCTGGGGCA
TAATCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTGCAGGAGATTTG
CCCGGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTTTGAGTTCCCTG
GAGTCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAGGCTACAGAGGG
CCACCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCCTAAAATGAAAT
CCAAGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGTGGATGTTGTAG
ACCGGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGCTGCGGAAACTG
AAGGCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGAAAGATACCTGG
ATGTTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTATGAACTATTTAT
TTCCTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTCTAGACCATTTA
TATACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGACTATCCTTTCAA
TATTTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTTTGTTTTTCTTG
TTTTGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGAAGCTCATCAGA
CACTGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCTATGATATGTAA
CAAGTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCTCCTAATACTTA
CTTAAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGAAATAGCAATTA
AGAAATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAACAACCATCAAT
TTTTTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTCCTAAGAAACTG
CCTTCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAAAATATCAATTT
TTTAAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTCAAGATACTGAA
AAATAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGCACTGGTCTGCA
TTTGGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTCCTTTCTTTTCT
CCATTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAGAAAAACTTGGT
CTTAGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGCTAAAACCAACT
TGTGCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGATAATAAGAGAA
CGTGCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCCATAAATGCAAT
AATATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTGAAGAAAATTCA
GGAAGAAACGTGTTAATAAACATTGTACTGTTCTTTTGCTTCTCAAAGGAATTATTCACTTGCCACTTTGGTTATTTTTGAGTTTTCGTA
CATAGGAAGTTTTATATTGCCAGCCTTCCTGTGATAAAGATATTAAATGTAACTTGAGTAAAAAATAAAAAAGAATAACTATGTATATAC

>77986_77986_1_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759389_ENST00000402538_length(amino acids)=365AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPT
VINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKP
TFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVT
GSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQ

--------------------------------------------------------------
>77986_77986_2_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759389_ENST00000403687_length(transcript)=3235nt_BP=251nt
GCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCCCAGGACCCGGG
AGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCCCTGGCCGCTCA
TGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCTGGACCTCTATC
ACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCAGCCTACCTCCCCTACGACGCCCAACAAGC
CTGTGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATTAGTGGAGTCTG
TATTTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTTCTTGGATTCCT
TCTGTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCAACTACACTGTA
AAATGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATTTCTCTGGGGCA
TAATCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTGCAGGAGATTTG
CCCGGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTTTGAGTTCCCTG
GAGTCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAGGCTACAGAGGG
CCACCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCCTAAAATGAAAT
CCAAGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGTGGATGTTGTAG
ACCGGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGCTGCGGAAACTG
AAGGCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGAAAGATACCTGG
ATGTTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTATGAACTATTTAT
TTCCTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTCTAGACCATTTA
TATACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGACTATCCTTTCAA
TATTTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTTTGTTTTTCTTG
TTTTGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGAAGCTCATCAGA
CACTGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCTATGATATGTAA
CAAGTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCTCCTAATACTTA
CTTAAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGAAATAGCAATTA
AGAAATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAACAACCATCAAT
TTTTTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTCCTAAGAAACTG
CCTTCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAAAATATCAATTT
TTTAAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTCAAGATACTGAA
AAATAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGCACTGGTCTGCA
TTTGGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTCCTTTCTTTTCT
CCATTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAGAAAAACTTGGT
CTTAGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGCTAAAACCAACT
TGTGCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGATAATAAGAGAA
CGTGCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCCATAAATGCAAT
AATATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTGAAGAAAATTCA
GGAAGAAACGTGTTAATAAACATTGTACTGTTCTTTTGCTTCTCAAAGGAATTATTCACTTGCCACTTTGGTTATTTTTGAGTTTTCGTA

>77986_77986_2_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759389_ENST00000403687_length(amino acids)=365AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPT
VINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKP
TFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVT
GSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQ

--------------------------------------------------------------
>77986_77986_3_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759389_ENST00000407811_length(transcript)=3106nt_BP=251nt
GCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCCCAGGACCCGGG
AGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCCCTGGCCGCTCA
TGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCTGGACCTCTATC
ACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCCTACCTCCCCTACGACGCCCAACAAGCCTG
TGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATTAGTGGAGTCTGTAT
TTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTTCTTGGATTCCTTCT
GTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCAACTACACTGTAAAA
TGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATTTCTCTGGGGCATAA
TCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTGCAGGAGATTTGCCC
GGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTTTGAGTTCCCTGGAG
TCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAGGCTACAGAGGGCCA
CCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCCTAAAATGAAATCCA
AGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGTGGATGTTGTAGACC
GGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGCTGCGGAAACTGAAG
GCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGAAAGATACCTGGATG
TTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTATGAACTATTTATTTC
CTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTCTAGACCATTTATAT
ACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGACTATCCTTTCAATAT
TTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTTTGTTTTTCTTGTTT
TGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGAAGCTCATCAGACAC
TGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCTATGATATGTAACAA
GTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCTCCTAATACTTACTT
AAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGAAATAGCAATTAAGA
AATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAACAACCATCAATTTT
TTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTCCTAAGAAACTGCCT
TCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAAAATATCAATTTTTT
AAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTCAAGATACTGAAAAA
TAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGCACTGGTCTGCATTT
GGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTCCTTTCTTTTCTCCA
TTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAGAAAAACTTGGTCTT
AGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGCTAAAACCAACTTGT
GCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGATAATAAGAGAACGT
GCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCCATAAATGCAATAAT
ATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTGAAGAAAATTCAGGA

>77986_77986_3_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759389_ENST00000407811_length(amino acids)=364AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTV
INKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKPT
FCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTG
SSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQD

--------------------------------------------------------------
>77986_77986_4_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759390_ENST00000402538_length(transcript)=3254nt_BP=251nt
GCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCCCAGGACCCGGG
AGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCCCTGGCCGCTCA
TGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCTGGACCTCTATC
ACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCAGCCTACCTCCCCTACGACGCCCAACAAGC
CTGTGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATTAGTGGAGTCTG
TATTTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTTCTTGGATTCCT
TCTGTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCAACTACACTGTA
AAATGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATTTCTCTGGGGCA
TAATCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTGCAGGAGATTTG
CCCGGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTTTGAGTTCCCTG
GAGTCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAGGCTACAGAGGG
CCACCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCCTAAAATGAAAT
CCAAGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGTGGATGTTGTAG
ACCGGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGCTGCGGAAACTG
AAGGCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGAAAGATACCTGG
ATGTTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTATGAACTATTTAT
TTCCTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTCTAGACCATTTA
TATACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGACTATCCTTTCAA
TATTTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTTTGTTTTTCTTG
TTTTGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGAAGCTCATCAGA
CACTGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCTATGATATGTAA
CAAGTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCTCCTAATACTTA
CTTAAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGAAATAGCAATTA
AGAAATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAACAACCATCAAT
TTTTTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTCCTAAGAAACTG
CCTTCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAAAATATCAATTT
TTTAAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTCAAGATACTGAA
AAATAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGCACTGGTCTGCA
TTTGGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTCCTTTCTTTTCT
CCATTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAGAAAAACTTGGT
CTTAGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGCTAAAACCAACT
TGTGCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGATAATAAGAGAA
CGTGCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCCATAAATGCAAT
AATATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTGAAGAAAATTCA
GGAAGAAACGTGTTAATAAACATTGTACTGTTCTTTTGCTTCTCAAAGGAATTATTCACTTGCCACTTTGGTTATTTTTGAGTTTTCGTA
CATAGGAAGTTTTATATTGCCAGCCTTCCTGTGATAAAGATATTAAATGTAACTTGAGTAAAAAATAAAAAAGAATAACTATGTATATAC

>77986_77986_4_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759390_ENST00000402538_length(amino acids)=365AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPT
VINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKP
TFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVT
GSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQ

--------------------------------------------------------------
>77986_77986_5_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759390_ENST00000403687_length(transcript)=3235nt_BP=251nt
GCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCCCAGGACCCGGG
AGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCCCTGGCCGCTCA
TGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCTGGACCTCTATC
ACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCAGCCTACCTCCCCTACGACGCCCAACAAGC
CTGTGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATTAGTGGAGTCTG
TATTTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTTCTTGGATTCCT
TCTGTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCAACTACACTGTA
AAATGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATTTCTCTGGGGCA
TAATCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTGCAGGAGATTTG
CCCGGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTTTGAGTTCCCTG
GAGTCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAGGCTACAGAGGG
CCACCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCCTAAAATGAAAT
CCAAGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGTGGATGTTGTAG
ACCGGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGCTGCGGAAACTG
AAGGCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGAAAGATACCTGG
ATGTTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTATGAACTATTTAT
TTCCTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTCTAGACCATTTA
TATACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGACTATCCTTTCAA
TATTTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTTTGTTTTTCTTG
TTTTGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGAAGCTCATCAGA
CACTGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCTATGATATGTAA
CAAGTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCTCCTAATACTTA
CTTAAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGAAATAGCAATTA
AGAAATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAACAACCATCAAT
TTTTTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTCCTAAGAAACTG
CCTTCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAAAATATCAATTT
TTTAAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTCAAGATACTGAA
AAATAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGCACTGGTCTGCA
TTTGGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTCCTTTCTTTTCT
CCATTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAGAAAAACTTGGT
CTTAGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGCTAAAACCAACT
TGTGCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGATAATAAGAGAA
CGTGCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCCATAAATGCAAT
AATATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTGAAGAAAATTCA
GGAAGAAACGTGTTAATAAACATTGTACTGTTCTTTTGCTTCTCAAAGGAATTATTCACTTGCCACTTTGGTTATTTTTGAGTTTTCGTA

>77986_77986_5_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759390_ENST00000403687_length(amino acids)=365AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPT
VINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKP
TFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVT
GSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQ

--------------------------------------------------------------
>77986_77986_6_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759390_ENST00000407811_length(transcript)=3106nt_BP=251nt
GCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCCCAGGACCCGGG
AGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCCCTGGCCGCTCA
TGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCTGGACCTCTATC
ACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCCTACCTCCCCTACGACGCCCAACAAGCCTG
TGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATTAGTGGAGTCTGTAT
TTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTTCTTGGATTCCTTCT
GTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCAACTACACTGTAAAA
TGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATTTCTCTGGGGCATAA
TCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTGCAGGAGATTTGCCC
GGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTTTGAGTTCCCTGGAG
TCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAGGCTACAGAGGGCCA
CCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCCTAAAATGAAATCCA
AGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGTGGATGTTGTAGACC
GGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGCTGCGGAAACTGAAG
GCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGAAAGATACCTGGATG
TTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTATGAACTATTTATTTC
CTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTCTAGACCATTTATAT
ACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGACTATCCTTTCAATAT
TTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTTTGTTTTTCTTGTTT
TGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGAAGCTCATCAGACAC
TGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCTATGATATGTAACAA
GTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCTCCTAATACTTACTT
AAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGAAATAGCAATTAAGA
AATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAACAACCATCAATTTT
TTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTCCTAAGAAACTGCCT
TCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAAAATATCAATTTTTT
AAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTCAAGATACTGAAAAA
TAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGCACTGGTCTGCATTT
GGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTCCTTTCTTTTCTCCA
TTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAGAAAAACTTGGTCTT
AGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGCTAAAACCAACTTGT
GCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGATAATAAGAGAACGT
GCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCCATAAATGCAATAAT
ATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTGAAGAAAATTCAGGA

>77986_77986_6_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374166_RASGRP3_chr2_33759390_ENST00000407811_length(amino acids)=364AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTV
INKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKPT
FCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTG
SSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQD

--------------------------------------------------------------
>77986_77986_7_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759389_ENST00000402538_length(transcript)=3265nt_BP=262nt
CTAGTGCCGCGGCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCC
CAGGACCCGGGAGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCC
CTGGCCGCTCATGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCT
GGACCTCTATCACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCAGCCTACCTCCCCTACGAC
GCCCAACAAGCCTGTGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATT
AGTGGAGTCTGTATTTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTT
CTTGGATTCCTTCTGTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCA
ACTACACTGTAAAATGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATT
TCTCTGGGGCATAATCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTG
CAGGAGATTTGCCCGGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTT
TGAGTTCCCTGGAGTCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAG
GCTACAGAGGGCCACCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCC
TAAAATGAAATCCAAGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGT
GGATGTTGTAGACCGGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGC
TGCGGAAACTGAAGGCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGA
AAGATACCTGGATGTTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTAT
GAACTATTTATTTCCTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTC
TAGACCATTTATATACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGAC
TATCCTTTCAATATTTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTT
TGTTTTTCTTGTTTTGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGA
AGCTCATCAGACACTGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCT
ATGATATGTAACAAGTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCT
CCTAATACTTACTTAAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGA
AATAGCAATTAAGAAATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAA
CAACCATCAATTTTTTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTC
CTAAGAAACTGCCTTCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAA
AATATCAATTTTTTAAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTC
AAGATACTGAAAAATAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGC
ACTGGTCTGCATTTGGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTC
CTTTCTTTTCTCCATTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAG
AAAAACTTGGTCTTAGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGC
TAAAACCAACTTGTGCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGA
TAATAAGAGAACGTGCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCC
ATAAATGCAATAATATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTG
AAGAAAATTCAGGAAGAAACGTGTTAATAAACATTGTACTGTTCTTTTGCTTCTCAAAGGAATTATTCACTTGCCACTTTGGTTATTTTT
GAGTTTTCGTACATAGGAAGTTTTATATTGCCAGCCTTCCTGTGATAAAGATATTAAATGTAACTTGAGTAAAAAATAAAAAAGAATAAC

>77986_77986_7_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759389_ENST00000402538_length(amino acids)=365AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPT
VINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKP
TFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVT
GSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQ

--------------------------------------------------------------
>77986_77986_8_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759389_ENST00000403687_length(transcript)=3246nt_BP=262nt
CTAGTGCCGCGGCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCC
CAGGACCCGGGAGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCC
CTGGCCGCTCATGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCT
GGACCTCTATCACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCAGCCTACCTCCCCTACGAC
GCCCAACAAGCCTGTGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATT
AGTGGAGTCTGTATTTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTT
CTTGGATTCCTTCTGTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCA
ACTACACTGTAAAATGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATT
TCTCTGGGGCATAATCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTG
CAGGAGATTTGCCCGGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTT
TGAGTTCCCTGGAGTCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAG
GCTACAGAGGGCCACCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCC
TAAAATGAAATCCAAGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGT
GGATGTTGTAGACCGGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGC
TGCGGAAACTGAAGGCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGA
AAGATACCTGGATGTTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTAT
GAACTATTTATTTCCTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTC
TAGACCATTTATATACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGAC
TATCCTTTCAATATTTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTT
TGTTTTTCTTGTTTTGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGA
AGCTCATCAGACACTGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCT
ATGATATGTAACAAGTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCT
CCTAATACTTACTTAAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGA
AATAGCAATTAAGAAATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAA
CAACCATCAATTTTTTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTC
CTAAGAAACTGCCTTCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAA
AATATCAATTTTTTAAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTC
AAGATACTGAAAAATAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGC
ACTGGTCTGCATTTGGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTC
CTTTCTTTTCTCCATTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAG
AAAAACTTGGTCTTAGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGC
TAAAACCAACTTGTGCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGA
TAATAAGAGAACGTGCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCC
ATAAATGCAATAATATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTG
AAGAAAATTCAGGAAGAAACGTGTTAATAAACATTGTACTGTTCTTTTGCTTCTCAAAGGAATTATTCACTTGCCACTTTGGTTATTTTT
GAGTTTTCGTACATAGGAAGTTTTATATTGCCAGCCTTCCTGTGATAAAGATATTAAATGTAACTTGAGTAAAAAATAAAAAAGAATAAC

>77986_77986_8_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759389_ENST00000403687_length(amino acids)=365AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPT
VINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKP
TFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVT
GSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQ

--------------------------------------------------------------
>77986_77986_9_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759389_ENST00000407811_length(transcript)=3117nt_BP=262nt
CTAGTGCCGCGGCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCC
CAGGACCCGGGAGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCC
CTGGCCGCTCATGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCT
GGACCTCTATCACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCCTACCTCCCCTACGACGCC
CAACAAGCCTGTGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATTAGT
GGAGTCTGTATTTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTTCTT
GGATTCCTTCTGTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCAACT
ACACTGTAAAATGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATTTCT
CTGGGGCATAATCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTGCAG
GAGATTTGCCCGGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTTTGA
GTTCCCTGGAGTCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAGGCT
ACAGAGGGCCACCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCCTAA
AATGAAATCCAAGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGTGGA
TGTTGTAGACCGGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGCTGC
GGAAACTGAAGGCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGAAAG
ATACCTGGATGTTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTATGAA
CTATTTATTTCCTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTCTAG
ACCATTTATATACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGACTAT
CCTTTCAATATTTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTTTGT
TTTTCTTGTTTTGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGAAGC
TCATCAGACACTGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCTATG
ATATGTAACAAGTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCTCCT
AATACTTACTTAAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGAAAT
AGCAATTAAGAAATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAACAA
CCATCAATTTTTTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTCCTA
AGAAACTGCCTTCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAAAAT
ATCAATTTTTTAAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTCAAG
ATACTGAAAAATAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGCACT
GGTCTGCATTTGGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTCCTT
TCTTTTCTCCATTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAGAAA
AACTTGGTCTTAGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGCTAA
AACCAACTTGTGCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGATAA
TAAGAGAACGTGCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCCATA
AATGCAATAATATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTGAAG

>77986_77986_9_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759389_ENST00000407811_length(amino acids)=364AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTV
INKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKPT
FCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTG
SSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQD

--------------------------------------------------------------
>77986_77986_10_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759390_ENST00000402538_length(transcript)=3265nt_BP=262nt
CTAGTGCCGCGGCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCC
CAGGACCCGGGAGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCC
CTGGCCGCTCATGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCT
GGACCTCTATCACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCAGCCTACCTCCCCTACGAC
GCCCAACAAGCCTGTGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATT
AGTGGAGTCTGTATTTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTT
CTTGGATTCCTTCTGTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCA
ACTACACTGTAAAATGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATT
TCTCTGGGGCATAATCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTG
CAGGAGATTTGCCCGGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTT
TGAGTTCCCTGGAGTCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAG
GCTACAGAGGGCCACCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCC
TAAAATGAAATCCAAGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGT
GGATGTTGTAGACCGGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGC
TGCGGAAACTGAAGGCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGA
AAGATACCTGGATGTTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTAT
GAACTATTTATTTCCTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTC
TAGACCATTTATATACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGAC
TATCCTTTCAATATTTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTT
TGTTTTTCTTGTTTTGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGA
AGCTCATCAGACACTGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCT
ATGATATGTAACAAGTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCT
CCTAATACTTACTTAAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGA
AATAGCAATTAAGAAATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAA
CAACCATCAATTTTTTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTC
CTAAGAAACTGCCTTCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAA
AATATCAATTTTTTAAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTC
AAGATACTGAAAAATAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGC
ACTGGTCTGCATTTGGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTC
CTTTCTTTTCTCCATTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAG
AAAAACTTGGTCTTAGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGC
TAAAACCAACTTGTGCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGA
TAATAAGAGAACGTGCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCC
ATAAATGCAATAATATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTG
AAGAAAATTCAGGAAGAAACGTGTTAATAAACATTGTACTGTTCTTTTGCTTCTCAAAGGAATTATTCACTTGCCACTTTGGTTATTTTT
GAGTTTTCGTACATAGGAAGTTTTATATTGCCAGCCTTCCTGTGATAAAGATATTAAATGTAACTTGAGTAAAAAATAAAAAAGAATAAC

>77986_77986_10_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759390_ENST00000402538_length(amino acids)=365AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPT
VINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKP
TFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVT
GSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQ

--------------------------------------------------------------
>77986_77986_11_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759390_ENST00000403687_length(transcript)=3246nt_BP=262nt
CTAGTGCCGCGGCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCC
CAGGACCCGGGAGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCC
CTGGCCGCTCATGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCT
GGACCTCTATCACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCAGCCTACCTCCCCTACGAC
GCCCAACAAGCCTGTGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATT
AGTGGAGTCTGTATTTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTT
CTTGGATTCCTTCTGTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCA
ACTACACTGTAAAATGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATT
TCTCTGGGGCATAATCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTG
CAGGAGATTTGCCCGGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTT
TGAGTTCCCTGGAGTCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAG
GCTACAGAGGGCCACCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCC
TAAAATGAAATCCAAGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGT
GGATGTTGTAGACCGGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGC
TGCGGAAACTGAAGGCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGA
AAGATACCTGGATGTTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTAT
GAACTATTTATTTCCTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTC
TAGACCATTTATATACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGAC
TATCCTTTCAATATTTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTT
TGTTTTTCTTGTTTTGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGA
AGCTCATCAGACACTGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCT
ATGATATGTAACAAGTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCT
CCTAATACTTACTTAAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGA
AATAGCAATTAAGAAATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAA
CAACCATCAATTTTTTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTC
CTAAGAAACTGCCTTCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAA
AATATCAATTTTTTAAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTC
AAGATACTGAAAAATAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGC
ACTGGTCTGCATTTGGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTC
CTTTCTTTTCTCCATTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAG
AAAAACTTGGTCTTAGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGC
TAAAACCAACTTGTGCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGA
TAATAAGAGAACGTGCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCC
ATAAATGCAATAATATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTG
AAGAAAATTCAGGAAGAAACGTGTTAATAAACATTGTACTGTTCTTTTGCTTCTCAAAGGAATTATTCACTTGCCACTTTGGTTATTTTT
GAGTTTTCGTACATAGGAAGTTTTATATTGCCAGCCTTCCTGTGATAAAGATATTAAATGTAACTTGAGTAAAAAATAAAAAAGAATAAC

>77986_77986_11_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759390_ENST00000403687_length(amino acids)=365AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPT
VINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKP
TFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVT
GSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQ

--------------------------------------------------------------
>77986_77986_12_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759390_ENST00000407811_length(transcript)=3117nt_BP=262nt
CTAGTGCCGCGGCGGCGGCGGCGGACGGCCCAGCCGGAGCGCGAGGGGCTCGGGGGGGCGCGGCGGTTCGGGTCGCAGAGCCAGGGACCC
CAGGACCCGGGAGGCGGCGCAGCCGGGGCCGCCGGAGGAGCGCGGGTGACCTGGCGGCGGCGAGATGCCGCTCGCCCAGCTCAAGGAGCC
CTGGCCGCTCATGGAGCTAGTGCCTCTGGACCCGGAGAATGGACAGACCTCAGGGGAAGAAGCTGGACTTCAGCCGTCCAAGCTTTCCCT
GGACCTCTATCACACTGAAGATGATATTTACAAACTGTCACTGGTGCTGGAGCCTAGAAATTCTAAATCGCCTACCTCCCCTACGACGCC
CAACAAGCCTGTGGTACCCCTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATAAGGAAATTAGT
GGAGTCTGTATTTAGAAACTATGATCACGACCATGATGGGTACATTTCCCAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTTCTT
GGATTCCTTCTGTGTTCTGGACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCTAAATCCCAACT
ACACTGTAAAATGGGACCAGGATTTATCCATAATTTTCAGGAGATGACCTATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATTTCT
CTGGGGCATAATCAAGCAAGGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTTCTGGCCTGCAG
GAGATTTGCCCGGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCTGGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTTTGA
GTTCCCTGGAGTCACTGCTGGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATCTCTGTGAGGCT
ACAGAGGGCCACCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCAGAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCCTAA
AATGAAATCCAAGTTCCATGACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCATGCTGGTGTGGA
TGTTGTAGACCGGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAAGAGACCAGACAGGATGGTGAGGATGGCTGACTTCAGGCTGC
GGAAACTGAAGGCAATAATGTTGGCTTTTGGAAGGGGCAAGACGAGAAACTCTGAAGAAAGCTCTGACTCTCAGGAAGTTATCTGGAAAG
ATACCTGGATGTTTACTGCCTTGGGACACTGTGGGATCTCCATGTTTGGACTATGGGACAGAGAATTGACCCTAACTAACTAACTATGAA
CTATTTATTTCCTCCTCCCCTACCCCTAGTTAAGTGCCACAAAGACTGTGTTATGTAGTCAGTACTTTTTTCTCATGTATCTTTCTCTAG
ACCATTTATATACGGGTGAAATGAAAGCTTTTTTGCATGTACTTGATACTCAGTCTGTAAACTCAGACTTCGCTTTTTTTGTGAGACTAT
CCTTTCAATATTTTTATAAACTTTTGTGTGTGCTGTGGCAGGGAACAGTTAACAAGGAGTTTATTTAGAGGGGTTTTTTTCATTTTTTGT
TTTTCTTGTTTTGTTTTGTTTTGTTTTGTTCTTCTTGGTGTGCTTTTTGGATGGGACCAGAACTTAACATTTTCCTGAGGACTAGGAAGC
TCATCAGACACTGGAATGCAGTGATTCTTCTAATGATGGTCAACTGCAAGGAGAAACTGTTTACATCCTTCCCACTACACAGTTGCTATG
ATATGTAACAAGTCACACATGTATATATCACACAAGTCTTACCAATTCTGCGTCACTAGGAAGCTATAGCATGGTCGTGAAAGCTCTCCT
AATACTTACTTAAATAGCCATGGAAGAAAATTATGCTTGTCCCTTCTGACTGGGTTAAGCCATCTTTCTTAAGATTCCTGAAGTAGAAAT
AGCAATTAAGAAATTAATTCAAGTTTTGACGGTTAACATTTAGCAGAAAAACAAACCATTGAATAAGCTACTAGGTGAAATGCAAAACAA
CCATCAATTTTTTTAAACTCAATAATTTTGTGAAAAAAAAAACCACCACCAAACTTTTGGTTGTAAAAGAGAACCCTTGTTCCCTTCCTA
AGAAACTGCCTTCCACAATTAAAGAATACTCATAGAAAGAAAATAATCATAAATCATATTTGATTAACATTTCATTTAAGCTTTTAAAAT
ATCAATTTTTTAAATAGCTCCCATTTACCCAAAATAACTAGTTATGGGTCTATTTCTTCCATGATTAGAGGAGAGAGAACTTGATTCAAG
ATACTGAAAAATAGAGCTGGGACTGAGCCTGTGAATGACAGGAATGATCTATTACCAGGTGACTAGTCGGAAACTACACAGACGTGCACT
GGTCTGCATTTGGGGGCTAAAGTGTATATATTCCATTTAAAATGGAATTTGTTTGTATTTGGGGCAGTCTTCAGTAAAGCCTTTCTCCTT
TCTTTTCTCCATTGAGGACAGTTCTGCTCAGCAAAATTGTTGAGTACCTGTTCTGGGCAGGTCCCACGCTATATGCACAAAGTTAAGAAA
AACTTGGTCTTAGCCCTTGGGAGCTGACAGCCCATGGGCATTAAGGCAAAGTAGTTCCAGTGATTTAAAATACGGTTCCAAATACGCTAA
AACCAACTTGTGCCAACCAGATTTACAGATTGGAAATACTGCAGATGATGTGAAGTTATCAGTTGGAGGAGCTGTGATTAAGCTGGATAA
TAAGAGAACGTGCCATCTGTAAAGCACTCAGAAGGCAGCCATCCCTAGATGTTGGTTTCATGTATATTACACTATCTACTACTATCCATA
AATGCAATAATATGCATGTTAACAACATTAAAAACAGCAAACAGCAATCTAAGTACAGAAAAGCTTTTTGTGTGTTTAAAAAAATTGAAG

>77986_77986_12_RPS6KA1-RASGRP3_RPS6KA1_chr1_26863460_ENST00000374168_RASGRP3_chr2_33759390_ENST00000407811_length(amino acids)=364AA_BP=36
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTV
INKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKPT
FCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTG
SSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQD

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Fusion Gene PPI Analysis for RPS6KA1-RASGRP3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RPS6KA1-RASGRP3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RPS6KA1-RASGRP3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource