FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:RPS6KC1-LPGAT1 (FusionGDB2 ID:78061)

Fusion Gene Summary for RPS6KC1-LPGAT1

check button Fusion gene summary
Fusion gene informationFusion gene name: RPS6KC1-LPGAT1
Fusion gene ID: 78061
HgeneTgene
Gene symbol

RPS6KC1

LPGAT1

Gene ID

26750

9926

Gene nameribosomal protein S6 kinase C1lysophosphatidylglycerol acyltransferase 1
SynonymsRPK118|RSKL1|S6K-delta-1|S6PKh1|humS6PKh1FAM34A|FAM34A1|NET8
Cytomap

1q32.3

1q32.3

Type of geneprotein-codingprotein-coding
Descriptionribosomal protein S6 kinase delta-152 kDa ribosomal protein S6 kinaseSPHK1-binding proteinribosomal S6 kinase-like protein with two PSK domains 118 kDa proteinribosomal protein S6 kinase, 52kDa, polypeptide 1acyl-CoA:lysophosphatidylglycerol acyltransferase 1family with sequence similarity 34, member A
Modification date2020032020200313
UniProtAcc.

Q92604

Ensembl transtripts involved in fusion geneENST00000490299, ENST00000366959, 
ENST00000366960, ENST00000543354, 
ENST00000543470, 		ENST00000366996, 
ENST00000366997, ENST00000488600, 
Fusion gene scores* DoF score17 X 16 X 8=21768 X 7 X 5=280
# samples 178
** MAII scorelog2(17/2176*10)=-3.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RPS6KC1 [Title/Abstract] AND LPGAT1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRPS6KC1(213251158)-LPGAT1(211966532), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across RPS6KC1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LPGAT1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerERR315366RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-


Top

Fusion Gene ORF analysis for RPS6KC1-LPGAT1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000490299ENST00000366996RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
3UTR-3CDSENST00000490299ENST00000366997RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
3UTR-intronENST00000490299ENST00000488600RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
5CDS-intronENST00000366959ENST00000488600RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
5CDS-intronENST00000366960ENST00000488600RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
5UTR-3CDSENST00000543354ENST00000366996RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
5UTR-3CDSENST00000543354ENST00000366997RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
5UTR-3CDSENST00000543470ENST00000366996RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
5UTR-3CDSENST00000543470ENST00000366997RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
5UTR-intronENST00000543354ENST00000488600RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
5UTR-intronENST00000543470ENST00000488600RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
In-frameENST00000366959ENST00000366996RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
In-frameENST00000366959ENST00000366997RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
In-frameENST00000366960ENST00000366996RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-
In-frameENST00000366960ENST00000366997RPS6KC1chr1

213251158

+LPGAT1chr1

211966532

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000366960RPS6KC1chr1213251158+ENST00000366997LPGAT1chr1211966532-77294121501286378
ENST00000366960RPS6KC1chr1213251158+ENST00000366996LPGAT1chr1211966532-13934121501286378
ENST00000366959RPS6KC1chr1213251158+ENST00000366997LPGAT1chr1211966532-76933761501250366
ENST00000366959RPS6KC1chr1213251158+ENST00000366996LPGAT1chr1211966532-13573761501250366

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000366960ENST00000366997RPS6KC1chr1213251158+LPGAT1chr1211966532-0.0001604730.99983954
ENST00000366960ENST00000366996RPS6KC1chr1213251158+LPGAT1chr1211966532-0.0004117170.9995883
ENST00000366959ENST00000366997RPS6KC1chr1213251158+LPGAT1chr1211966532-0.0001801150.99981993
ENST00000366959ENST00000366996RPS6KC1chr1213251158+LPGAT1chr1211966532-0.0005344490.9994655

Top

Fusion Genomic Features for RPS6KC1-LPGAT1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for RPS6KC1-LPGAT1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:213251158/chr1:211966532)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.LPGAT1

Q92604

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes the transfert of an acyl group from an acyl-CoA to a lysophosphatidylglycerol (LPG) leading to biosynthesis of phosphatidylglycerol, a precursor for cardiolipin synthesis (PubMed:15485873). Uses various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors (PubMed:15485873). Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor (PubMed:15485873). In vitro can also catalyzes the transfert of an acyl group from an acyl-CoA to a monoacylglycerol leading to diacylglycerol synthesis, a precursor of triacylglycerol and plays a role in hepatic triacylglycerol synthesis and secretion (By similarity). Prefers the sn-2-monoacylglycerol to rac-1-monoacylglycerol as acyl acceptor (By similarity). {ECO:0000250|UniProtKB:Q91YX5, ECO:0000269|PubMed:15485873}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLPGAT1chr1:213251158chr1:211966532ENST0000036699618101_10679371.0MotifNote=HXXXXD motif
TgeneLPGAT1chr1:213251158chr1:211966532ENST0000036699718101_10679371.0MotifNote=HXXXXD motif
TgeneLPGAT1chr1:213251158chr1:211966532ENST0000036699618342_36279371.0TransmembraneHelical
TgeneLPGAT1chr1:213251158chr1:211966532ENST0000036699718342_36279371.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRPS6KC1chr1:213251158chr1:211966532ENST00000366959+214277_305751055.0DomainNote=MIT
HgeneRPS6KC1chr1:213251158chr1:211966532ENST00000366959+214344_445751055.0DomainProtein kinase 1
HgeneRPS6KC1chr1:213251158chr1:211966532ENST00000366959+214794_1056751055.0DomainProtein kinase 2
HgeneRPS6KC1chr1:213251158chr1:211966532ENST00000366959+2148_132751055.0DomainPX
HgeneRPS6KC1chr1:213251158chr1:211966532ENST00000366960+315277_305871067.0DomainNote=MIT
HgeneRPS6KC1chr1:213251158chr1:211966532ENST00000366960+315344_445871067.0DomainProtein kinase 1
HgeneRPS6KC1chr1:213251158chr1:211966532ENST00000366960+315794_1056871067.0DomainProtein kinase 2
HgeneRPS6KC1chr1:213251158chr1:211966532ENST00000366960+3158_132871067.0DomainPX
HgeneRPS6KC1chr1:213251158chr1:211966532ENST00000366959+214801_809751055.0Nucleotide bindingATP
HgeneRPS6KC1chr1:213251158chr1:211966532ENST00000366960+315801_809871067.0Nucleotide bindingATP
TgeneLPGAT1chr1:213251158chr1:211966532ENST000003669961822_4279371.0TransmembraneHelical
TgeneLPGAT1chr1:213251158chr1:211966532ENST000003669971822_4279371.0TransmembraneHelical


Top

Fusion Gene Sequence for RPS6KC1-LPGAT1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>78061_78061_1_RPS6KC1-LPGAT1_RPS6KC1_chr1_213251158_ENST00000366959_LPGAT1_chr1_211966532_ENST00000366996_length(transcript)=1357nt_BP=376nt
GCTGTGCAGCTGAGGCGCCGCCGTGGAGCCGCCTTGGAGCCACCGCCCCCTCGCCGCTTCGCCGCTGCGTTGGGGAACCTGGACCGCGGC
GGCGCCGGGTTTCCCTCATGATCCCGGGCGGGTGGCGGCGGCGGCAGAGGCGGCGGGAGGATGACCTCTTACCGGGAGCGGAGTGCCGAC
CTGGCCCGTTTCTACACTGTCACCGAGCCCCAGCGACACCCGAGGGGCTACACAGTATATAAGGTCACCGCCCGGATAATTGTATGGAAG
AGATACAGTGATTTTAAGAAACTACACAAAGAACTATGGCAAATTCACAAAAACTTATTCCGACATTCAGAGTTGTTTCCTCCATTTGCT
AAAGGAATAGTGTTTGTGATGGAATGGGGAGAAGATATTAAAGCAGTTTCAAAAGATGAAGCAGTGATGTTGGTGAATCATCAGGCAACA
GGAGATGTGTGCACACTGATGATGTGCCTCCAGGACAAAGGACTGGTTGTTGCTCAGATGATGTGGTTGATGGATCATATTTTTAAGTAC
ACAAACTTTGGAATTGTTTCTCTAGTTCATGGAGACTTCTTTATAAGACAGGGAAGATCTTATCGTGACCAACAGCTGCTGCTTCTCAAG
AAGCACTTAGAAAATAATTACAGGAGCAGAGATCGAAAATGGATTGTTTTGTTTCCAGAAGGGGGCTTCCTCAGGAAGAGGCGAGAAACA
AGTCAGGCATTTGCCAAGAAAAATAACTTGCCATTTCTTACAAATGTTACTCTGCCAAGGTCTGGGGCAACAAAAATTATTTTGAATGCA
CTTGTAGCACAACAGAAAAATGGAAGTCCAGCAGGAGGAGATGCTAAAGAATTAGACAGCAAATCAAAAGGCCTCCAGTGGATAATAGAT
ACAACGATAGCTTATCCCAAAGCTGAACCTATAGATATTCAAACCTGGATCCTTGGATACAGGAAACCAACAGTCACACATGTACATTAC
AGGATCTTTCCAATTAAAGATGTACCCCTGGAGACTGATGACCTTACCACTTGGCTCTATCAGCGGTTTGTTGAAAAAGAAGACCTCTTA
TCACATTTTTATGAAACAGGAGCTTTTCCACCTTCCAAGGGCCATAAGGAAGCTGTTTCCAGGGAGATGACCCTCAGCAACTTGTGGATA
TTTCTCATACAGTCTTTTGCATTTTTGTCAGGCTATATGTGGTACAACATCATTCAGTATTTTTACCATTGCCTGTTTTAGGAATTGACG
TGGACTTGTCAAGGTCACCGTAGGAGTTCAGACTTTCTTTCATAAGTGTGCATTATTTTACATGTGCAAATCAGAATATATTTAAAAAAA

>78061_78061_1_RPS6KC1-LPGAT1_RPS6KC1_chr1_213251158_ENST00000366959_LPGAT1_chr1_211966532_ENST00000366996_length(amino acids)=366AA_BP=75
MTSYRERSADLARFYTVTEPQRHPRGYTVYKVTARIIVWKRYSDFKKLHKELWQIHKNLFRHSELFPPFAKGIVFVMEWGEDIKAVSKDE
AVMLVNHQATGDVCTLMMCLQDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRSRDRKWIVLFPE
GGFLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDAKELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILGY
RKPTVTHVHYRIFPIKDVPLETDDLTTWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNLWIFLIQSFAFLSGYMWYNIIQY

--------------------------------------------------------------
>78061_78061_2_RPS6KC1-LPGAT1_RPS6KC1_chr1_213251158_ENST00000366959_LPGAT1_chr1_211966532_ENST00000366997_length(transcript)=7693nt_BP=376nt
GCTGTGCAGCTGAGGCGCCGCCGTGGAGCCGCCTTGGAGCCACCGCCCCCTCGCCGCTTCGCCGCTGCGTTGGGGAACCTGGACCGCGGC
GGCGCCGGGTTTCCCTCATGATCCCGGGCGGGTGGCGGCGGCGGCAGAGGCGGCGGGAGGATGACCTCTTACCGGGAGCGGAGTGCCGAC
CTGGCCCGTTTCTACACTGTCACCGAGCCCCAGCGACACCCGAGGGGCTACACAGTATATAAGGTCACCGCCCGGATAATTGTATGGAAG
AGATACAGTGATTTTAAGAAACTACACAAAGAACTATGGCAAATTCACAAAAACTTATTCCGACATTCAGAGTTGTTTCCTCCATTTGCT
AAAGGAATAGTGTTTGTGATGGAATGGGGAGAAGATATTAAAGCAGTTTCAAAAGATGAAGCAGTGATGTTGGTGAATCATCAGGCAACA
GGAGATGTGTGCACACTGATGATGTGCCTCCAGGACAAAGGACTGGTTGTTGCTCAGATGATGTGGTTGATGGATCATATTTTTAAGTAC
ACAAACTTTGGAATTGTTTCTCTAGTTCATGGAGACTTCTTTATAAGACAGGGAAGATCTTATCGTGACCAACAGCTGCTGCTTCTCAAG
AAGCACTTAGAAAATAATTACAGGAGCAGAGATCGAAAATGGATTGTTTTGTTTCCAGAAGGGGGCTTCCTCAGGAAGAGGCGAGAAACA
AGTCAGGCATTTGCCAAGAAAAATAACTTGCCATTTCTTACAAATGTTACTCTGCCAAGGTCTGGGGCAACAAAAATTATTTTGAATGCA
CTTGTAGCACAACAGAAAAATGGAAGTCCAGCAGGAGGAGATGCTAAAGAATTAGACAGCAAATCAAAAGGCCTCCAGTGGATAATAGAT
ACAACGATAGCTTATCCCAAAGCTGAACCTATAGATATTCAAACCTGGATCCTTGGATACAGGAAACCAACAGTCACACATGTACATTAC
AGGATCTTTCCAATTAAAGATGTACCCCTGGAGACTGATGACCTTACCACTTGGCTCTATCAGCGGTTTGTTGAAAAAGAAGACCTCTTA
TCACATTTTTATGAAACAGGAGCTTTTCCACCTTCCAAGGGCCATAAGGAAGCTGTTTCCAGGGAGATGACCCTCAGCAACTTGTGGATA
TTTCTCATACAGTCTTTTGCATTTTTGTCAGGCTATATGTGGTACAACATCATTCAGTATTTTTACCATTGCCTGTTTTAGGAATTGACG
TGGACTTGTCAAGGTCACCGTAGGAGTTCAGACTTTCTTTCATAAGTGTGCATTATTTTACATGTGCAAATCAGAATATATTTAAAAAAA
AGCAAAAGAAATTCAATGGATGGATTAATATTTATCCCCCTTTGGGATATTTTAAAATCTACTAAAATGAGGATTAGTAATATAATGACC
TGCTAATATATTTTAAGAACATGTTTTAAAAAGATACACTCTATCACATATTTAAGCAAACATCACATTTGGAGAAGAGGAAATCATAAA
ATCATCCTAGAAGACTATCTGAGAGAAATTCTGTTGCCACCAGTTATACTTGACAATTTAGTTGAAGCTCAGAAAGTTATATTCATCCCT
CTTAGCTGTAGTCTATATTAGGGCAGTTCTCTAGAACGCCCACATTTCCACCAACTCAGTAAACTTGAGGGGAGCTGGTTGGCACCTCGT
GAAGAACTCTTTCCCTGTCGTTTGCAGTAACAAACTCCAGTCTGTTGCAGTAACAAACTCCAGTCTGTTGCAGTAACAAACTCTAGAATA
TTGACATTCTCTGTGGGGGAAAAGCAGTGTCCACTGGACCCCTTCTGGTACTGGATGTGTTCTTTACAAAGGCTAGCTCAGTCCAACACT
GTGTTTACATACACTCGTGCTTTTCCTTATCTGACTTCTCATTTTGTATCAGAGGCATATCATAAATTGATAATTTTGCAAAATGCACTT
TTTTGAGATGCAGATATAGCAAAGGATTAGTAATATAGCCTGAAAACAAATGGGAGCATAGCAGTGTGTGAGGTTCTCGAGAACTGTCTT
GTCTCTGTGTGTTTATTTGCCTGCCAGTGCTCTCCAGCGCCATCCTGCCCTGGACACCACCCTGACGTGATGCCTCTATTGCAGCTCAGA
GGCTTTATTTTTTCCATTTTGACATTGGCACTAAATGCATTTGGGGATGGTTAAAACAAATTACTATAGAACATTTAAATGATCAGTTTA
AGGGGAAATAGGCTAGTTTATAGAAAAATAAGAGCTAGTGGCTTATAATGGTGACAGGTTCTCATGTGGCACCCCTAGGACCTGTGCAGA
CAGTAGTCTGTTGAATCATTACATCAAGGAGCTGCCCCTGTCAGGGTGAGTGTAATTAGGAACGATACCAGCACATAAGGCTCCCCCCAA
TCTCTTCCAGTTGCTTTTTCTTTTTTCTTTTTTTTTTAGACAGGTCTTACTCTGTCACCCAGGCTGTAGTGCAGTGGCATAATCTCAGCT
CACTGCAGTCTCTGCCTCCCGGGTTCGAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCACCATCATGCTTGG
CTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGCCTCGAACTCCTGACCTCAGGTGATCTGCCCACCTCG
GCTTCCTAAAGTGCTGGGATTGCAGGCGTGAGCCACCACGCCCGGCCTCCAGTTGCTTTTGAAGAGGGTAAAGTCAAGTTTCTATTTCTA
GAAAACATTTTTTAGAAATTTGTTGCGATGTTTGTACAATTTACCTCATAAGAGAACCACACCCTTCTCCAAAAGTGCTGGTACTGCATC
AGTGAGATGAGTAGGGTTTTTGTTTGGGATTGTAAGACTATTAAGATCCTAGTAAGTCAGTGGTAGTTTACTGTGATGTGAGCATTGTAG
ATTCCCCCGTTGTCACTAATCACACAACAATTTTGAGAAGTAGGCTATAAAACAAAAAAAGGTTGCTGTTTTCTATTTTTAAATAAACCA
AAAAAAAACAGAAAAGATGTGAATTTTCCCCAGTTATGTGGGAAAGGTAAAGCAACACCAAATAAAAGCCCACAGCAGCTTCATCTTTAC
GATAACTCAGTGCATATGTGAAAGAGAATGATGCATTAACTGAAATACCTCATTGAATATTATACTACTACTGGTAAAATGCAGAAGACA
GTGTTAATGTGTTTGGTTTGGGGACTGGTTGTTATAAAATGCAATTTTTTTTTAAATCTAAGCATTTCATTATGTGTTCTACAGTGTCGG
TGAATAAATGAAACCAATCTCAATTTAGAGGTATGGATGATGACAGAAAGCCCAATAGAAGCTTAATGATGCTTCTGTTTGAGGCCCAGC
AAGCACCACTAAATTACTGGATGAAATGAAATTGTTCACTTGAGGGATTAGTCAACCATCTGGGGGAGAAGTTGCTCACTGTCAAATACA
GCATGCACGGTCCTAGCTGATAGACCTTTTCCTCATTGCTACAGCAAGCCACAGGGTAGAGTGACCAGTTCTCCTATCCAAAAATAAATG
CGAACATGCATACATAAATGTGGCTGAGGGCCACTTTTGCCATCACTGTGCTCCAAAGGAACATGATATTGTTAAATATACTGTACACAT
TAAACTATTCTATAAGATGCTTTACTTTTCAAGTACGGTGTCATTTTCACAGTCTCCAGGGTGACAAATGCCAATAGATATGTGAGTTAA
TTTTTTTAAATATCTCCGTGAGTTGTAAATAGATGTGTATTTGATCTGCCCTATCCTTCTTTGATTCTTTAACATGTTCTCTCTCTTCTG
TTTGCAAAATATGTTTGAAAGCATTGGTAGTGCTTTCCTTATCAGTAACTGGAGTTCTCCTGCTTGCACTAGAGAAGGTAAAGAGAGAAT
CAGTATTCTTATATGGCAATCTGGGGAAGCAGCAATATGCCACTGTACAAAACTGAAGAAAAGTTCCTAATTTGTACTTTGTGAAGGGAG
ATGAAAGGACGTTTAAAGTATATATATTTTGTCAAGAGGAAAGAAGATAAAACTATGCCAGTTTTATATCAATAGCTTGTAGAAGCTCAG
CTCTTCTTGGTCTTGGCTAGACTGCCTAGATTCCCACAGCAGACAAGGTTGAGAATCCATTGCTGGAATCTTGGTATTGATGAGTTACAG
TGATGGAACATGTGCTTGGCCACAGGCAGGTCCAGTCACTGCAAAAGTGACCAAGCCAGCAGGTCACCCTTAACTTCAGAAACAATTATT
GGTGGTGAACTGTACTTAAATTGCAGAGAAACCTGTAAGTAATGGAAGGTAAAGAAAAATTACAGAATGGAAAATAATATTTTGGGCAAG
CAAACAAATTCACTGAGAATTCCAAAAGTATATTAAAAAAGAAGATAGCTATGAGTTCAGATCTATCTTATTGGTCTTTAATATTACAAC
CAATCCTTAACTTTCCACTATAAAGGAAGGATTACTAGATTGATTACTTTCTGGATAGATAATCTGGTAATAAATGATAGGTAAATCAAA
AATTACTTTTATTTAGGAGTTTGAATTCTTACTCTCATCAGACATTTTTTTTCTAGGGACGCTTACTAATTAAATGATTTAAGTTGTTTC
TTAGGGGTTTTTTGCCTATATATTTATGACTGTGTTAATGAGTAGTGAAATGATGCGGAAAGACAGCTATCAGGAAGAGGAAATACAGAA
GCCTGAATAATCTATGGGTTAGAAAAGCATCCCTGAATAATCAAAAATTGGCAGTATTGGCATTGTTCTCAAGCCTTTTTATGAAAATGA
AATCTGAAATCACCAAATGTAAACCTGGGAACATTATTCTAGTGTTGCTGTCTTGGATTCATGTTAAGAAGCGTCTTCATTCTTTGCTCA
TGTTGCCCACTTCTTGTGGATTTGTCTGAGTGTTTTTTGACAATCACTTCCTTAAAGACTCTTCTGAACTAGTTGGACCTGGTTAATCAT
AGAGAGTAGCCTTTAATCATGGATAGTCTTCTTGGATTATTTTTATATTTGAAAAGAAAATGTTTTATTTGCACTACTGAGTAGGAAGAG
TTAATTGTTTTCTTTGTTCTTTTTTTGAAGTCATTACACAGGACTTCACTCCAGAGTTACCATTATGAGTGTGTTCAGCTCTGGTCCACA
GAGGATGGATAAAAATGGTTTGTTATGTTTTTTTGCTCTGCAGTGCTATGAGCCTTATATCTGTTAATATGAAGGACAAAGTCAAAAGCA
GCAGTGGATAGCAGGAAGGGTAGAGACTAATATGTTTGGGACCAAAACCATCTAAGTTAGAGATTTCCAGATCACAGAGGGGCTGGGCAT
TCTCTGGAGCAGTCATTGGTTGGTGCTTTATTGTAATCATTTTGCGCCAATCCCCAACAATTAGGAACTGGACCCTGGGAATAAGCTGAG
GGTGCTGAACTGTTGGGGAAGGGTGACTGTAGCCACATGGAAGATAAAATATGGGTTTTTCTGCAAAATTTCCATCTGAGGGTTTTTACA
TTTAATATTTTTTTAAGACAGTTTAAAGAGCAAACGTTTTTTAAGTGTATTCTAGTTGCAAAGTATGCACACATATCTTGAATGGCTTTA
TTTTTATTGTGTAAAACTGTTGAACACATGACTGTGATGCACAAATTCTTTACGTGTAAGGAGTCTATGCATTTTACAGTAACTTATTTT
ATGATCGGGTGATGAGACAGTTATACTTTCAACTGCCATTATTTTTATTAAGTGCTTTCATTTTCTTTACAGTTATTATAAAATTGTATT
TATTTTATACAGATGGGTTTTCATTTTCCTGATGCTGTAATGTTTACTTCAGCTTGTTGACCTTTCTTTGTGTTATCTGCATGTTGTAAC
GTGTGATAAGAATGAATGTAAAGGCTGTGGCAACTGTAATTAATTTTTGTAAAGGGCTGGTCACACGTGGATCTGGTTTATGAATGCATT
TGGGATGATTTTGGTAACCAGATCACCTTTTCAGAAATTTAGATGTGAACACCAAAAGAAGCATTTTCTCAACAAAAATTAATAGCTGGT
TCTATTTTTTTTAAACCTAGAAAAAATAAAGTTGATTTTTTTCAATTAAAGTGCTTTTAATTCTTAGCAGTGGGGATGGGGCATGTGTGT
TTTACCAGAGCTATTTGGGCATTAATATCTGCAGGCAAGTACTTAAAGCACACTGTGGCAGTTGGATGCTGAAGGCAAACTGAAAAACCA
AATGAAAAAACATCAGACTTCCTTCTTTGGTTTAAAAATATTTCCCCCTTTCTCCCCATTCTCCCAATCCAGTGGTGTGCTGGTAAATGT
TTAGCAGTTCACTCTTCTGGGAGAAAATTATGTATTCAACTATACATGTTTGTTATAAATTTTGCTGATAGCAAGAACATATAACACAAT
TAACAAATAATAAGATACAAATACTTTATTGTAAATCCCATATAGCCAGTTGATTCTCACAGTATACTTAGTTGCTCAGGAAAGAACTAA
AATGCTTTTTTAAAAGGATACTTAATTGCTTTTTGCTCAACTCCTACAGTCAACCTATGATTGATTGTCTTTCAACTGTGATTTGAAAAA
TGGCAGACTGTCCAAATCTAACTCATTTCCCAATAAATTTATTATCATTCAATCTGATACGTGATCTACTGTTAAAACTGTTTCTTACCA
TGGTACATATTAGACTCATTAAGCCGAAACCACTTTTAGCTTTAACATTAATTGTAAATTTATATGATTCAATTTTCATAACCAATGCTT
AACAACTGCAGGCAAAATTCTAAAATGTGACCACTGGGTCTTGGGAATCAGTAGGGGCTGTATCCAGCACACCACTGCCCCATCCTTTTT
TTCTTAACTATTAGTGTTGAATAAACTTCTCATAGTTAATCTACTTGCTGAACTCAGGAAATTCCTATCACTGACCCTGGCCAGGGCTTT
AAAGGGTAGGAAAAGCATTAATGTCAGTCCTACACAGCGAACTTTTGATTTAGAAGAATGTGACAGAAAGAAAACATTTACTGAAATACA
TGGGAAGCTTGCATATTTCTAAAGTTGTCTTTATACTTTTCATTTCTCAAAGCTAAGTAAACTGTGGTATAGGCATCTCTAAGATGTTAG
CATTTAAAACATCAATTGTTTTATTGATGTTTAAACAATTGTTTAAATCCCACTGAAAAATTTAAATATTAAAATATCTTGCACAGTCTA
CCAAATGAGTTAAATCGTTACAGTCGTGTCTACCTCTTATTTTTCTATCTGTATTTAGGCTGCTGTTTTGGTGAGATTCTAATTTCTTTT
TCCCCTGGAACTACTTTCTGTGGAAGACAAGGAACAGACTGGGGACAGAGGCCTGAAAACAAATTGGAAGCACTCAGAGATCTATTGCTG
ACCAGCCCTATTCCTCATGAGTTGGCGGGGGGAAAGCCATTGTTTTTAATTTCCACTTAATATGAAAATGCTTGTTTTTAAAATGTTTTT
TCCTGCTGAACAAATGTATTTTTAAAAGGAAAAAAATTCTCTTTTGGCTCTAAGAAGTCAGCTGTATGAGCAGGCGTGACCATATCATAA

>78061_78061_2_RPS6KC1-LPGAT1_RPS6KC1_chr1_213251158_ENST00000366959_LPGAT1_chr1_211966532_ENST00000366997_length(amino acids)=366AA_BP=75
MTSYRERSADLARFYTVTEPQRHPRGYTVYKVTARIIVWKRYSDFKKLHKELWQIHKNLFRHSELFPPFAKGIVFVMEWGEDIKAVSKDE
AVMLVNHQATGDVCTLMMCLQDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRSRDRKWIVLFPE
GGFLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDAKELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILGY
RKPTVTHVHYRIFPIKDVPLETDDLTTWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNLWIFLIQSFAFLSGYMWYNIIQY

--------------------------------------------------------------
>78061_78061_3_RPS6KC1-LPGAT1_RPS6KC1_chr1_213251158_ENST00000366960_LPGAT1_chr1_211966532_ENST00000366996_length(transcript)=1393nt_BP=412nt
GCTGTGCAGCTGAGGCGCCGCCGTGGAGCCGCCTTGGAGCCACCGCCCCCTCGCCGCTTCGCCGCTGCGTTGGGGAACCTGGACCGCGGC
GGCGCCGGGTTTCCCTCATGATCCCGGGCGGGTGGCGGCGGCGGCAGAGGCGGCGGGAGGATGACCTCTTACCGGGAGCGGAGTGCCGAC
CTGGCCCGTTTCTACACTGTCACCGAGCCCCAGCGACACCCGAGGGGCTACACAGTATATAAGGTCACCGCCCGGGTTGTTTCACGAAGA
AATCCAGAGGATGTCCAGGAGATAATTGTATGGAAGAGATACAGTGATTTTAAGAAACTACACAAAGAACTATGGCAAATTCACAAAAAC
TTATTCCGACATTCAGAGTTGTTTCCTCCATTTGCTAAAGGAATAGTGTTTGTGATGGAATGGGGAGAAGATATTAAAGCAGTTTCAAAA
GATGAAGCAGTGATGTTGGTGAATCATCAGGCAACAGGAGATGTGTGCACACTGATGATGTGCCTCCAGGACAAAGGACTGGTTGTTGCT
CAGATGATGTGGTTGATGGATCATATTTTTAAGTACACAAACTTTGGAATTGTTTCTCTAGTTCATGGAGACTTCTTTATAAGACAGGGA
AGATCTTATCGTGACCAACAGCTGCTGCTTCTCAAGAAGCACTTAGAAAATAATTACAGGAGCAGAGATCGAAAATGGATTGTTTTGTTT
CCAGAAGGGGGCTTCCTCAGGAAGAGGCGAGAAACAAGTCAGGCATTTGCCAAGAAAAATAACTTGCCATTTCTTACAAATGTTACTCTG
CCAAGGTCTGGGGCAACAAAAATTATTTTGAATGCACTTGTAGCACAACAGAAAAATGGAAGTCCAGCAGGAGGAGATGCTAAAGAATTA
GACAGCAAATCAAAAGGCCTCCAGTGGATAATAGATACAACGATAGCTTATCCCAAAGCTGAACCTATAGATATTCAAACCTGGATCCTT
GGATACAGGAAACCAACAGTCACACATGTACATTACAGGATCTTTCCAATTAAAGATGTACCCCTGGAGACTGATGACCTTACCACTTGG
CTCTATCAGCGGTTTGTTGAAAAAGAAGACCTCTTATCACATTTTTATGAAACAGGAGCTTTTCCACCTTCCAAGGGCCATAAGGAAGCT
GTTTCCAGGGAGATGACCCTCAGCAACTTGTGGATATTTCTCATACAGTCTTTTGCATTTTTGTCAGGCTATATGTGGTACAACATCATT
CAGTATTTTTACCATTGCCTGTTTTAGGAATTGACGTGGACTTGTCAAGGTCACCGTAGGAGTTCAGACTTTCTTTCATAAGTGTGCATT

>78061_78061_3_RPS6KC1-LPGAT1_RPS6KC1_chr1_213251158_ENST00000366960_LPGAT1_chr1_211966532_ENST00000366996_length(amino acids)=378AA_BP=87
MTSYRERSADLARFYTVTEPQRHPRGYTVYKVTARVVSRRNPEDVQEIIVWKRYSDFKKLHKELWQIHKNLFRHSELFPPFAKGIVFVME
WGEDIKAVSKDEAVMLVNHQATGDVCTLMMCLQDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYR
SRDRKWIVLFPEGGFLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDAKELDSKSKGLQWIIDTTIAYPKA
EPIDIQTWILGYRKPTVTHVHYRIFPIKDVPLETDDLTTWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNLWIFLIQSFAF

--------------------------------------------------------------
>78061_78061_4_RPS6KC1-LPGAT1_RPS6KC1_chr1_213251158_ENST00000366960_LPGAT1_chr1_211966532_ENST00000366997_length(transcript)=7729nt_BP=412nt
GCTGTGCAGCTGAGGCGCCGCCGTGGAGCCGCCTTGGAGCCACCGCCCCCTCGCCGCTTCGCCGCTGCGTTGGGGAACCTGGACCGCGGC
GGCGCCGGGTTTCCCTCATGATCCCGGGCGGGTGGCGGCGGCGGCAGAGGCGGCGGGAGGATGACCTCTTACCGGGAGCGGAGTGCCGAC
CTGGCCCGTTTCTACACTGTCACCGAGCCCCAGCGACACCCGAGGGGCTACACAGTATATAAGGTCACCGCCCGGGTTGTTTCACGAAGA
AATCCAGAGGATGTCCAGGAGATAATTGTATGGAAGAGATACAGTGATTTTAAGAAACTACACAAAGAACTATGGCAAATTCACAAAAAC
TTATTCCGACATTCAGAGTTGTTTCCTCCATTTGCTAAAGGAATAGTGTTTGTGATGGAATGGGGAGAAGATATTAAAGCAGTTTCAAAA
GATGAAGCAGTGATGTTGGTGAATCATCAGGCAACAGGAGATGTGTGCACACTGATGATGTGCCTCCAGGACAAAGGACTGGTTGTTGCT
CAGATGATGTGGTTGATGGATCATATTTTTAAGTACACAAACTTTGGAATTGTTTCTCTAGTTCATGGAGACTTCTTTATAAGACAGGGA
AGATCTTATCGTGACCAACAGCTGCTGCTTCTCAAGAAGCACTTAGAAAATAATTACAGGAGCAGAGATCGAAAATGGATTGTTTTGTTT
CCAGAAGGGGGCTTCCTCAGGAAGAGGCGAGAAACAAGTCAGGCATTTGCCAAGAAAAATAACTTGCCATTTCTTACAAATGTTACTCTG
CCAAGGTCTGGGGCAACAAAAATTATTTTGAATGCACTTGTAGCACAACAGAAAAATGGAAGTCCAGCAGGAGGAGATGCTAAAGAATTA
GACAGCAAATCAAAAGGCCTCCAGTGGATAATAGATACAACGATAGCTTATCCCAAAGCTGAACCTATAGATATTCAAACCTGGATCCTT
GGATACAGGAAACCAACAGTCACACATGTACATTACAGGATCTTTCCAATTAAAGATGTACCCCTGGAGACTGATGACCTTACCACTTGG
CTCTATCAGCGGTTTGTTGAAAAAGAAGACCTCTTATCACATTTTTATGAAACAGGAGCTTTTCCACCTTCCAAGGGCCATAAGGAAGCT
GTTTCCAGGGAGATGACCCTCAGCAACTTGTGGATATTTCTCATACAGTCTTTTGCATTTTTGTCAGGCTATATGTGGTACAACATCATT
CAGTATTTTTACCATTGCCTGTTTTAGGAATTGACGTGGACTTGTCAAGGTCACCGTAGGAGTTCAGACTTTCTTTCATAAGTGTGCATT
ATTTTACATGTGCAAATCAGAATATATTTAAAAAAAAGCAAAAGAAATTCAATGGATGGATTAATATTTATCCCCCTTTGGGATATTTTA
AAATCTACTAAAATGAGGATTAGTAATATAATGACCTGCTAATATATTTTAAGAACATGTTTTAAAAAGATACACTCTATCACATATTTA
AGCAAACATCACATTTGGAGAAGAGGAAATCATAAAATCATCCTAGAAGACTATCTGAGAGAAATTCTGTTGCCACCAGTTATACTTGAC
AATTTAGTTGAAGCTCAGAAAGTTATATTCATCCCTCTTAGCTGTAGTCTATATTAGGGCAGTTCTCTAGAACGCCCACATTTCCACCAA
CTCAGTAAACTTGAGGGGAGCTGGTTGGCACCTCGTGAAGAACTCTTTCCCTGTCGTTTGCAGTAACAAACTCCAGTCTGTTGCAGTAAC
AAACTCCAGTCTGTTGCAGTAACAAACTCTAGAATATTGACATTCTCTGTGGGGGAAAAGCAGTGTCCACTGGACCCCTTCTGGTACTGG
ATGTGTTCTTTACAAAGGCTAGCTCAGTCCAACACTGTGTTTACATACACTCGTGCTTTTCCTTATCTGACTTCTCATTTTGTATCAGAG
GCATATCATAAATTGATAATTTTGCAAAATGCACTTTTTTGAGATGCAGATATAGCAAAGGATTAGTAATATAGCCTGAAAACAAATGGG
AGCATAGCAGTGTGTGAGGTTCTCGAGAACTGTCTTGTCTCTGTGTGTTTATTTGCCTGCCAGTGCTCTCCAGCGCCATCCTGCCCTGGA
CACCACCCTGACGTGATGCCTCTATTGCAGCTCAGAGGCTTTATTTTTTCCATTTTGACATTGGCACTAAATGCATTTGGGGATGGTTAA
AACAAATTACTATAGAACATTTAAATGATCAGTTTAAGGGGAAATAGGCTAGTTTATAGAAAAATAAGAGCTAGTGGCTTATAATGGTGA
CAGGTTCTCATGTGGCACCCCTAGGACCTGTGCAGACAGTAGTCTGTTGAATCATTACATCAAGGAGCTGCCCCTGTCAGGGTGAGTGTA
ATTAGGAACGATACCAGCACATAAGGCTCCCCCCAATCTCTTCCAGTTGCTTTTTCTTTTTTCTTTTTTTTTTAGACAGGTCTTACTCTG
TCACCCAGGCTGTAGTGCAGTGGCATAATCTCAGCTCACTGCAGTCTCTGCCTCCCGGGTTCGAGCGATTCTCCTGCCTCAGCCTCCCGA
GTAGCTGGGACTACAGGCACCCACCATCATGCTTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGC
CTCGAACTCCTGACCTCAGGTGATCTGCCCACCTCGGCTTCCTAAAGTGCTGGGATTGCAGGCGTGAGCCACCACGCCCGGCCTCCAGTT
GCTTTTGAAGAGGGTAAAGTCAAGTTTCTATTTCTAGAAAACATTTTTTAGAAATTTGTTGCGATGTTTGTACAATTTACCTCATAAGAG
AACCACACCCTTCTCCAAAAGTGCTGGTACTGCATCAGTGAGATGAGTAGGGTTTTTGTTTGGGATTGTAAGACTATTAAGATCCTAGTA
AGTCAGTGGTAGTTTACTGTGATGTGAGCATTGTAGATTCCCCCGTTGTCACTAATCACACAACAATTTTGAGAAGTAGGCTATAAAACA
AAAAAAGGTTGCTGTTTTCTATTTTTAAATAAACCAAAAAAAAACAGAAAAGATGTGAATTTTCCCCAGTTATGTGGGAAAGGTAAAGCA
ACACCAAATAAAAGCCCACAGCAGCTTCATCTTTACGATAACTCAGTGCATATGTGAAAGAGAATGATGCATTAACTGAAATACCTCATT
GAATATTATACTACTACTGGTAAAATGCAGAAGACAGTGTTAATGTGTTTGGTTTGGGGACTGGTTGTTATAAAATGCAATTTTTTTTTA
AATCTAAGCATTTCATTATGTGTTCTACAGTGTCGGTGAATAAATGAAACCAATCTCAATTTAGAGGTATGGATGATGACAGAAAGCCCA
ATAGAAGCTTAATGATGCTTCTGTTTGAGGCCCAGCAAGCACCACTAAATTACTGGATGAAATGAAATTGTTCACTTGAGGGATTAGTCA
ACCATCTGGGGGAGAAGTTGCTCACTGTCAAATACAGCATGCACGGTCCTAGCTGATAGACCTTTTCCTCATTGCTACAGCAAGCCACAG
GGTAGAGTGACCAGTTCTCCTATCCAAAAATAAATGCGAACATGCATACATAAATGTGGCTGAGGGCCACTTTTGCCATCACTGTGCTCC
AAAGGAACATGATATTGTTAAATATACTGTACACATTAAACTATTCTATAAGATGCTTTACTTTTCAAGTACGGTGTCATTTTCACAGTC
TCCAGGGTGACAAATGCCAATAGATATGTGAGTTAATTTTTTTAAATATCTCCGTGAGTTGTAAATAGATGTGTATTTGATCTGCCCTAT
CCTTCTTTGATTCTTTAACATGTTCTCTCTCTTCTGTTTGCAAAATATGTTTGAAAGCATTGGTAGTGCTTTCCTTATCAGTAACTGGAG
TTCTCCTGCTTGCACTAGAGAAGGTAAAGAGAGAATCAGTATTCTTATATGGCAATCTGGGGAAGCAGCAATATGCCACTGTACAAAACT
GAAGAAAAGTTCCTAATTTGTACTTTGTGAAGGGAGATGAAAGGACGTTTAAAGTATATATATTTTGTCAAGAGGAAAGAAGATAAAACT
ATGCCAGTTTTATATCAATAGCTTGTAGAAGCTCAGCTCTTCTTGGTCTTGGCTAGACTGCCTAGATTCCCACAGCAGACAAGGTTGAGA
ATCCATTGCTGGAATCTTGGTATTGATGAGTTACAGTGATGGAACATGTGCTTGGCCACAGGCAGGTCCAGTCACTGCAAAAGTGACCAA
GCCAGCAGGTCACCCTTAACTTCAGAAACAATTATTGGTGGTGAACTGTACTTAAATTGCAGAGAAACCTGTAAGTAATGGAAGGTAAAG
AAAAATTACAGAATGGAAAATAATATTTTGGGCAAGCAAACAAATTCACTGAGAATTCCAAAAGTATATTAAAAAAGAAGATAGCTATGA
GTTCAGATCTATCTTATTGGTCTTTAATATTACAACCAATCCTTAACTTTCCACTATAAAGGAAGGATTACTAGATTGATTACTTTCTGG
ATAGATAATCTGGTAATAAATGATAGGTAAATCAAAAATTACTTTTATTTAGGAGTTTGAATTCTTACTCTCATCAGACATTTTTTTTCT
AGGGACGCTTACTAATTAAATGATTTAAGTTGTTTCTTAGGGGTTTTTTGCCTATATATTTATGACTGTGTTAATGAGTAGTGAAATGAT
GCGGAAAGACAGCTATCAGGAAGAGGAAATACAGAAGCCTGAATAATCTATGGGTTAGAAAAGCATCCCTGAATAATCAAAAATTGGCAG
TATTGGCATTGTTCTCAAGCCTTTTTATGAAAATGAAATCTGAAATCACCAAATGTAAACCTGGGAACATTATTCTAGTGTTGCTGTCTT
GGATTCATGTTAAGAAGCGTCTTCATTCTTTGCTCATGTTGCCCACTTCTTGTGGATTTGTCTGAGTGTTTTTTGACAATCACTTCCTTA
AAGACTCTTCTGAACTAGTTGGACCTGGTTAATCATAGAGAGTAGCCTTTAATCATGGATAGTCTTCTTGGATTATTTTTATATTTGAAA
AGAAAATGTTTTATTTGCACTACTGAGTAGGAAGAGTTAATTGTTTTCTTTGTTCTTTTTTTGAAGTCATTACACAGGACTTCACTCCAG
AGTTACCATTATGAGTGTGTTCAGCTCTGGTCCACAGAGGATGGATAAAAATGGTTTGTTATGTTTTTTTGCTCTGCAGTGCTATGAGCC
TTATATCTGTTAATATGAAGGACAAAGTCAAAAGCAGCAGTGGATAGCAGGAAGGGTAGAGACTAATATGTTTGGGACCAAAACCATCTA
AGTTAGAGATTTCCAGATCACAGAGGGGCTGGGCATTCTCTGGAGCAGTCATTGGTTGGTGCTTTATTGTAATCATTTTGCGCCAATCCC
CAACAATTAGGAACTGGACCCTGGGAATAAGCTGAGGGTGCTGAACTGTTGGGGAAGGGTGACTGTAGCCACATGGAAGATAAAATATGG
GTTTTTCTGCAAAATTTCCATCTGAGGGTTTTTACATTTAATATTTTTTTAAGACAGTTTAAAGAGCAAACGTTTTTTAAGTGTATTCTA
GTTGCAAAGTATGCACACATATCTTGAATGGCTTTATTTTTATTGTGTAAAACTGTTGAACACATGACTGTGATGCACAAATTCTTTACG
TGTAAGGAGTCTATGCATTTTACAGTAACTTATTTTATGATCGGGTGATGAGACAGTTATACTTTCAACTGCCATTATTTTTATTAAGTG
CTTTCATTTTCTTTACAGTTATTATAAAATTGTATTTATTTTATACAGATGGGTTTTCATTTTCCTGATGCTGTAATGTTTACTTCAGCT
TGTTGACCTTTCTTTGTGTTATCTGCATGTTGTAACGTGTGATAAGAATGAATGTAAAGGCTGTGGCAACTGTAATTAATTTTTGTAAAG
GGCTGGTCACACGTGGATCTGGTTTATGAATGCATTTGGGATGATTTTGGTAACCAGATCACCTTTTCAGAAATTTAGATGTGAACACCA
AAAGAAGCATTTTCTCAACAAAAATTAATAGCTGGTTCTATTTTTTTTAAACCTAGAAAAAATAAAGTTGATTTTTTTCAATTAAAGTGC
TTTTAATTCTTAGCAGTGGGGATGGGGCATGTGTGTTTTACCAGAGCTATTTGGGCATTAATATCTGCAGGCAAGTACTTAAAGCACACT
GTGGCAGTTGGATGCTGAAGGCAAACTGAAAAACCAAATGAAAAAACATCAGACTTCCTTCTTTGGTTTAAAAATATTTCCCCCTTTCTC
CCCATTCTCCCAATCCAGTGGTGTGCTGGTAAATGTTTAGCAGTTCACTCTTCTGGGAGAAAATTATGTATTCAACTATACATGTTTGTT
ATAAATTTTGCTGATAGCAAGAACATATAACACAATTAACAAATAATAAGATACAAATACTTTATTGTAAATCCCATATAGCCAGTTGAT
TCTCACAGTATACTTAGTTGCTCAGGAAAGAACTAAAATGCTTTTTTAAAAGGATACTTAATTGCTTTTTGCTCAACTCCTACAGTCAAC
CTATGATTGATTGTCTTTCAACTGTGATTTGAAAAATGGCAGACTGTCCAAATCTAACTCATTTCCCAATAAATTTATTATCATTCAATC
TGATACGTGATCTACTGTTAAAACTGTTTCTTACCATGGTACATATTAGACTCATTAAGCCGAAACCACTTTTAGCTTTAACATTAATTG
TAAATTTATATGATTCAATTTTCATAACCAATGCTTAACAACTGCAGGCAAAATTCTAAAATGTGACCACTGGGTCTTGGGAATCAGTAG
GGGCTGTATCCAGCACACCACTGCCCCATCCTTTTTTTCTTAACTATTAGTGTTGAATAAACTTCTCATAGTTAATCTACTTGCTGAACT
CAGGAAATTCCTATCACTGACCCTGGCCAGGGCTTTAAAGGGTAGGAAAAGCATTAATGTCAGTCCTACACAGCGAACTTTTGATTTAGA
AGAATGTGACAGAAAGAAAACATTTACTGAAATACATGGGAAGCTTGCATATTTCTAAAGTTGTCTTTATACTTTTCATTTCTCAAAGCT
AAGTAAACTGTGGTATAGGCATCTCTAAGATGTTAGCATTTAAAACATCAATTGTTTTATTGATGTTTAAACAATTGTTTAAATCCCACT
GAAAAATTTAAATATTAAAATATCTTGCACAGTCTACCAAATGAGTTAAATCGTTACAGTCGTGTCTACCTCTTATTTTTCTATCTGTAT
TTAGGCTGCTGTTTTGGTGAGATTCTAATTTCTTTTTCCCCTGGAACTACTTTCTGTGGAAGACAAGGAACAGACTGGGGACAGAGGCCT
GAAAACAAATTGGAAGCACTCAGAGATCTATTGCTGACCAGCCCTATTCCTCATGAGTTGGCGGGGGGAAAGCCATTGTTTTTAATTTCC
ACTTAATATGAAAATGCTTGTTTTTAAAATGTTTTTTCCTGCTGAACAAATGTATTTTTAAAAGGAAAAAAATTCTCTTTTGGCTCTAAG

>78061_78061_4_RPS6KC1-LPGAT1_RPS6KC1_chr1_213251158_ENST00000366960_LPGAT1_chr1_211966532_ENST00000366997_length(amino acids)=378AA_BP=87
MTSYRERSADLARFYTVTEPQRHPRGYTVYKVTARVVSRRNPEDVQEIIVWKRYSDFKKLHKELWQIHKNLFRHSELFPPFAKGIVFVME
WGEDIKAVSKDEAVMLVNHQATGDVCTLMMCLQDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYR
SRDRKWIVLFPEGGFLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDAKELDSKSKGLQWIIDTTIAYPKA
EPIDIQTWILGYRKPTVTHVHYRIFPIKDVPLETDDLTTWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNLWIFLIQSFAF

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for RPS6KC1-LPGAT1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for RPS6KC1-LPGAT1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for RPS6KC1-LPGAT1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource