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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RQCD1-ARPC2 (FusionGDB2 ID:78253)

Fusion Gene Summary for RQCD1-ARPC2

check button Fusion gene summary
Fusion gene informationFusion gene name: RQCD1-ARPC2
Fusion gene ID: 78253
HgeneTgene
Gene symbol

RQCD1

ARPC2

Gene ID

9125

10109

Gene nameCCR4-NOT transcription complex subunit 9actin related protein 2/3 complex subunit 2
SynonymsCAF40|CT129|RCD-1|RCD1|RQCD1ARC34|PNAS-139|PRO2446|p34-Arc
Cytomap

2q35

2q35

Type of geneprotein-codingprotein-coding
DescriptionCCR4-NOT transcription complex subunit 9RCD1 required for cell differentiation1 homologcancer/testis antigen 129cell differentiation protein RCD1 homologcell differentiation protein RQCD1 homologprotein involved in sexual developmentactin-related protein 2/3 complex subunit 2ARP2/3 protein complex subunit 34actin related protein 2/3 complex, subunit 2, 34kDaarp2/3 complex 34 kDa subunittestis tissue sperm-binding protein Li 53e
Modification date2020031320200313
UniProtAcc.

O15144

Ensembl transtripts involved in fusion geneENST00000489687, ENST00000273064, 
ENST00000295701, ENST00000509807, 
ENST00000542068, 		ENST00000295685, 
ENST00000315717, ENST00000477992, 
Fusion gene scores* DoF score4 X 3 X 5=6011 X 15 X 6=990
# samples 616
** MAII scorelog2(6/60*10)=0log2(16/990*10)=-2.62935662007961
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RQCD1 [Title/Abstract] AND ARPC2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRQCD1(219433701)-ARPC2(219103387), # samples:3
Anticipated loss of major functional domain due to fusion event.RQCD1-ARPC2 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
RQCD1-ARPC2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
RQCD1-ARPC2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRQCD1

GO:2000327

positive regulation of nuclear receptor transcription coactivator activity

18180299

TgeneARPC2

GO:0034314

Arp2/3 complex-mediated actin nucleation

11741539


check buttonFusion gene breakpoints across RQCD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARPC2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-55-7903-01ARQCD1chr2

219433701

+ARPC2chr2

219099075

+
ChimerDB4UCECTCGA-5B-A90C-01ARQCD1chr2

219433700

+ARPC2chr2

219103386

+
ChimerDB4UCECTCGA-5B-A90C-01ARQCD1chr2

219433701

-ARPC2chr2

219103387

+
ChimerDB4UCECTCGA-5B-A90C-01ARQCD1chr2

219433701

+ARPC2chr2

219103387

+
ChimerDB4UCECTCGA-5B-A90CRQCD1chr2

219433701

+ARPC2chr2

219103386

+
ChimerDB4UCECTCGA-5B-A90CRQCD1chr2

219433701

+ARPC2chr2

219103387

+


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Fusion Gene ORF analysis for RQCD1-ARPC2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000489687ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219099075

+
3UTR-3CDSENST00000489687ENST00000295685RQCD1chr2

219433700

+ARPC2chr2

219103386

+
3UTR-3CDSENST00000489687ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219103386

+
3UTR-3CDSENST00000489687ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219103387

+
3UTR-3CDSENST00000489687ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219099075

+
3UTR-3CDSENST00000489687ENST00000315717RQCD1chr2

219433700

+ARPC2chr2

219103386

+
3UTR-3CDSENST00000489687ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219103386

+
3UTR-3CDSENST00000489687ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219103387

+
3UTR-3UTRENST00000489687ENST00000477992RQCD1chr2

219433700

+ARPC2chr2

219103386

+
3UTR-3UTRENST00000489687ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219103386

+
3UTR-3UTRENST00000489687ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219103387

+
3UTR-intronENST00000489687ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219099075

+
5CDS-3UTRENST00000273064ENST00000477992RQCD1chr2

219433700

+ARPC2chr2

219103386

+
5CDS-3UTRENST00000273064ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219103386

+
5CDS-3UTRENST00000273064ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219103387

+
5CDS-3UTRENST00000295701ENST00000477992RQCD1chr2

219433700

+ARPC2chr2

219103386

+
5CDS-3UTRENST00000295701ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219103386

+
5CDS-3UTRENST00000295701ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219103387

+
5CDS-3UTRENST00000509807ENST00000477992RQCD1chr2

219433700

+ARPC2chr2

219103386

+
5CDS-3UTRENST00000509807ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219103386

+
5CDS-3UTRENST00000509807ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219103387

+
5CDS-3UTRENST00000542068ENST00000477992RQCD1chr2

219433700

+ARPC2chr2

219103386

+
5CDS-3UTRENST00000542068ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219103386

+
5CDS-3UTRENST00000542068ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219103387

+
5CDS-intronENST00000273064ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219099075

+
5CDS-intronENST00000295701ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219099075

+
5CDS-intronENST00000509807ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219099075

+
5CDS-intronENST00000542068ENST00000477992RQCD1chr2

219433701

+ARPC2chr2

219099075

+
Frame-shiftENST00000273064ENST00000295685RQCD1chr2

219433700

+ARPC2chr2

219103386

+
Frame-shiftENST00000273064ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219103386

+
Frame-shiftENST00000273064ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219103387

+
Frame-shiftENST00000273064ENST00000315717RQCD1chr2

219433700

+ARPC2chr2

219103386

+
Frame-shiftENST00000273064ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219103386

+
Frame-shiftENST00000273064ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219103387

+
Frame-shiftENST00000295701ENST00000295685RQCD1chr2

219433700

+ARPC2chr2

219103386

+
Frame-shiftENST00000295701ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219103386

+
Frame-shiftENST00000295701ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219103387

+
Frame-shiftENST00000295701ENST00000315717RQCD1chr2

219433700

+ARPC2chr2

219103386

+
Frame-shiftENST00000295701ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219103386

+
Frame-shiftENST00000295701ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219103387

+
Frame-shiftENST00000509807ENST00000295685RQCD1chr2

219433700

+ARPC2chr2

219103386

+
Frame-shiftENST00000509807ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219103386

+
Frame-shiftENST00000509807ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219103387

+
Frame-shiftENST00000509807ENST00000315717RQCD1chr2

219433700

+ARPC2chr2

219103386

+
Frame-shiftENST00000509807ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219103386

+
Frame-shiftENST00000509807ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219103387

+
Frame-shiftENST00000542068ENST00000295685RQCD1chr2

219433700

+ARPC2chr2

219103386

+
Frame-shiftENST00000542068ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219103386

+
Frame-shiftENST00000542068ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219103387

+
Frame-shiftENST00000542068ENST00000315717RQCD1chr2

219433700

+ARPC2chr2

219103386

+
Frame-shiftENST00000542068ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219103386

+
Frame-shiftENST00000542068ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219103387

+
In-frameENST00000273064ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219099075

+
In-frameENST00000273064ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219099075

+
In-frameENST00000295701ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219099075

+
In-frameENST00000295701ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219099075

+
In-frameENST00000509807ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219099075

+
In-frameENST00000509807ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219099075

+
In-frameENST00000542068ENST00000295685RQCD1chr2

219433701

+ARPC2chr2

219099075

+
In-frameENST00000542068ENST00000315717RQCD1chr2

219433701

+ARPC2chr2

219099075

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000509807RQCD1chr2219433701+ENST00000315717ARPC2chr2219099075+15133991681079303
ENST00000509807RQCD1chr2219433701+ENST00000295685ARPC2chr2219099075+15213991681079303
ENST00000273064RQCD1chr2219433701+ENST00000315717ARPC2chr2219099075+15133991681079303
ENST00000273064RQCD1chr2219433701+ENST00000295685ARPC2chr2219099075+15213991681079303
ENST00000542068RQCD1chr2219433701+ENST00000315717ARPC2chr2219099075+138527140951303
ENST00000542068RQCD1chr2219433701+ENST00000295685ARPC2chr2219099075+139327140951303
ENST00000295701RQCD1chr2219433701+ENST00000315717ARPC2chr2219099075+121810450784244
ENST00000295701RQCD1chr2219433701+ENST00000295685ARPC2chr2219099075+122610450784244

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000509807ENST00000315717RQCD1chr2219433701+ARPC2chr2219099075+0.0004618240.9995382
ENST00000509807ENST00000295685RQCD1chr2219433701+ARPC2chr2219099075+0.0004692650.9995308
ENST00000273064ENST00000315717RQCD1chr2219433701+ARPC2chr2219099075+0.0004618240.9995382
ENST00000273064ENST00000295685RQCD1chr2219433701+ARPC2chr2219099075+0.0004692650.9995308
ENST00000542068ENST00000315717RQCD1chr2219433701+ARPC2chr2219099075+0.0005507140.9994493
ENST00000542068ENST00000295685RQCD1chr2219433701+ARPC2chr2219099075+0.0005518970.9994481
ENST00000295701ENST00000315717RQCD1chr2219433701+ARPC2chr2219099075+0.0003707670.99962926
ENST00000295701ENST00000295685RQCD1chr2219433701+ARPC2chr2219099075+0.0003707290.99962926

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Fusion Genomic Features for RQCD1-ARPC2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RQCD1chr2219433701+ARPC2chr2219099074+8.16E-060.9999919
RQCD1chr2219433701+ARPC2chr2219103386+3.80E-070.99999964
RQCD1chr2219433701+ARPC2chr2219103386+3.80E-070.99999964
RQCD1chr2219433701+ARPC2chr2219099074+8.16E-060.9999919
RQCD1chr2219433701+ARPC2chr2219103386+3.80E-070.99999964
RQCD1chr2219433701+ARPC2chr2219103386+3.80E-070.99999964

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for RQCD1-ARPC2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:219433701/chr2:219103387)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ARPC2

O15144

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). Seems to contact the mother actin filament (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947). {ECO:0000269|PubMed:29925947, ECO:0000269|PubMed:9230079}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for RQCD1-ARPC2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>78253_78253_1_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000273064_ARPC2_chr2_219099075_ENST00000295685_length(transcript)=1521nt_BP=399nt
AGTTGTCTTGCCGGGACTGTCCATCTTTTCCCGCCGTTCACTGGCTTTTGGAGGAGGGTCAGAGTTCACGCCGCTCTCTGGAAATAACTG
CTCAAAGCCAGAAGTTGCGGGGACTAGTGGTCGCGGACGTCCTTCCGGTCCTAAATCTTAAGGGGCAAAGGACATACTCTGGGACTGTTA
ACTAGGCCCTGGAGGCGGGAAGAGGATGTGTGGGTGGGGTCAGGGGTGAGAGGTCAGAGGGCCGCGAAGTGGGCGGAGCGAGCCGGAGTC
GGATGGCGGCTACGGCGGCTCATTGTTTTCCGCTGCAGGGGTGCTGAAGGGGGGACGCGGGTCGGACGCGTCCGGCTGTGGAAGAGAGCG
GCGGCCGCTCACAACATGCACAGCCTGGCGACGGCTGCGTTATTAAAGAGGGTGTACGGGAGTTTCTTGGTAAATCCAGAATCAGGATAC
AATGTCTCTTTGCTATATGACCTTGAAAATCTTCCGGCATCCAAGGATTCCATTGTGCATCAAGCTGGCATGTTGAAGCGAAATTGTTTT
GCCTCTGTCTTTGAAAAATACTTCCAATTCCAAGAAGAGGGCAAGGAAGGAGAGAACAGGGCAGTTATCCATTATAGGGATGATGAGACC
ATGTATGTTGAGTCTAAAAAGGACAGAGTCACAGTAGTCTTCAGCACAGTGTTTAAGGATGACGACGATGTGGTCATTGGAAAGGTGTTC
ATGCAGGAGTTCAAAGAAGGACGCAGAGCCAGCCACACAGCCCCACAGGTCCTCTTTAGCCACAGGGAACCTCCTCTGGAGCTGAAAGAC
ACAGACGCCGCTGTGGGTGACAACATTGGCTACATTACCTTTGTGCTGTTCCCTCGTCACACCAATGCCAGTGCTCGAGACAACACCATC
AACCTGATCCACACGTTCCGGGACTACCTGCACTACCACATCAAGTGCTCTAAGGCCTATATTCACACACGTATGCGGGCGAAAACGTCT
GACTTCCTCAAGGTGCTGAACCGCGCACGCCCAGATGCCGAGAAAAAAGAAATGAAAACAATCACGGGGAAGACGTTTTCATCCCGCTAA
TCTTGGGAATAAGAGGAGGAAGCGGCTGGCAACTGAAGGCTGGAACACTTGCTACTGGATAATCGTAGCTTTTAATGTTGCGCCTCTTCA
GGTTCTTAAGGGATTCTCCGTTTTGGTTCCATTTTGTACACGTTTGGAAAATAATCTGCAGAAACGAGCTGTGCTTGCAAAGACTTCATA
GTTCCCAAGAATTAAAAAAAAAAAAAAAAGAATTCCACTTGATCAACTTAATTCCTTTTCTTTATCTTCCCTCCCTCACTTCCCTTTTCT
CCCACCCTCTTTTCCAAGCTGTTTCGCTTTGCAATATATTACTGGTAATGAGTTGCAGGATAATGCAGTCATAACTTGTTTTCTCCTAAG

>78253_78253_1_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000273064_ARPC2_chr2_219099075_ENST00000295685_length(amino acids)=303AA_BP=77
MGLLTRPWRREEDVWVGSGVRGQRAAKWAERAGVGWRLRRLIVFRCRGAEGGTRVGRVRLWKRAAAAHNMHSLATAALLKRVYGSFLVNP
ESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVI
GKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMR

--------------------------------------------------------------
>78253_78253_2_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000273064_ARPC2_chr2_219099075_ENST00000315717_length(transcript)=1513nt_BP=399nt
AGTTGTCTTGCCGGGACTGTCCATCTTTTCCCGCCGTTCACTGGCTTTTGGAGGAGGGTCAGAGTTCACGCCGCTCTCTGGAAATAACTG
CTCAAAGCCAGAAGTTGCGGGGACTAGTGGTCGCGGACGTCCTTCCGGTCCTAAATCTTAAGGGGCAAAGGACATACTCTGGGACTGTTA
ACTAGGCCCTGGAGGCGGGAAGAGGATGTGTGGGTGGGGTCAGGGGTGAGAGGTCAGAGGGCCGCGAAGTGGGCGGAGCGAGCCGGAGTC
GGATGGCGGCTACGGCGGCTCATTGTTTTCCGCTGCAGGGGTGCTGAAGGGGGGACGCGGGTCGGACGCGTCCGGCTGTGGAAGAGAGCG
GCGGCCGCTCACAACATGCACAGCCTGGCGACGGCTGCGTTATTAAAGAGGGTGTACGGGAGTTTCTTGGTAAATCCAGAATCAGGATAC
AATGTCTCTTTGCTATATGACCTTGAAAATCTTCCGGCATCCAAGGATTCCATTGTGCATCAAGCTGGCATGTTGAAGCGAAATTGTTTT
GCCTCTGTCTTTGAAAAATACTTCCAATTCCAAGAAGAGGGCAAGGAAGGAGAGAACAGGGCAGTTATCCATTATAGGGATGATGAGACC
ATGTATGTTGAGTCTAAAAAGGACAGAGTCACAGTAGTCTTCAGCACAGTGTTTAAGGATGACGACGATGTGGTCATTGGAAAGGTGTTC
ATGCAGGAGTTCAAAGAAGGACGCAGAGCCAGCCACACAGCCCCACAGGTCCTCTTTAGCCACAGGGAACCTCCTCTGGAGCTGAAAGAC
ACAGACGCCGCTGTGGGTGACAACATTGGCTACATTACCTTTGTGCTGTTCCCTCGTCACACCAATGCCAGTGCTCGAGACAACACCATC
AACCTGATCCACACGTTCCGGGACTACCTGCACTACCACATCAAGTGCTCTAAGGCCTATATTCACACACGTATGCGGGCGAAAACGTCT
GACTTCCTCAAGGTGCTGAACCGCGCACGCCCAGATGCCGAGAAAAAAGAAATGAAAACAATCACGGGGAAGACGTTTTCATCCCGCTAA
TCTTGGGAATAAGAGGAGGAAGCGGCTGGCAACTGAAGGCTGGAACACTTGCTACTGGATAATCGTAGCTTTTAATGTTGCGCCTCTTCA
GGTTCTTAAGGGATTCTCCGTTTTGGTTCCATTTTGTACACGTTTGGAAAATAATCTGCAGAAACGAGCTGTGCTTGCAAAGACTTCATA
GTTCCCAAGAATTAAAAAAAAAAAAAAAAGAATTCCACTTGATCAACTTAATTCCTTTTCTTTATCTTCCCTCCCTCACTTCCCTTTTCT
CCCACCCTCTTTTCCAAGCTGTTTCGCTTTGCAATATATTACTGGTAATGAGTTGCAGGATAATGCAGTCATAACTTGTTTTCTCCTAAG

>78253_78253_2_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000273064_ARPC2_chr2_219099075_ENST00000315717_length(amino acids)=303AA_BP=77
MGLLTRPWRREEDVWVGSGVRGQRAAKWAERAGVGWRLRRLIVFRCRGAEGGTRVGRVRLWKRAAAAHNMHSLATAALLKRVYGSFLVNP
ESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVI
GKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMR

--------------------------------------------------------------
>78253_78253_3_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000295701_ARPC2_chr2_219099075_ENST00000295685_length(transcript)=1226nt_BP=104nt
TTTTCCGCTGCAGGGGTGCTGAAGGGGGGACGCGGGTCGGACGCGTCCGGCTGTGGAAGAGAGCGGCGGCCGCTCACAACATGCACAGCC
TGGCGACGGCTGCGTTATTAAAGAGGGTGTACGGGAGTTTCTTGGTAAATCCAGAATCAGGATACAATGTCTCTTTGCTATATGACCTTG
AAAATCTTCCGGCATCCAAGGATTCCATTGTGCATCAAGCTGGCATGTTGAAGCGAAATTGTTTTGCCTCTGTCTTTGAAAAATACTTCC
AATTCCAAGAAGAGGGCAAGGAAGGAGAGAACAGGGCAGTTATCCATTATAGGGATGATGAGACCATGTATGTTGAGTCTAAAAAGGACA
GAGTCACAGTAGTCTTCAGCACAGTGTTTAAGGATGACGACGATGTGGTCATTGGAAAGGTGTTCATGCAGGAGTTCAAAGAAGGACGCA
GAGCCAGCCACACAGCCCCACAGGTCCTCTTTAGCCACAGGGAACCTCCTCTGGAGCTGAAAGACACAGACGCCGCTGTGGGTGACAACA
TTGGCTACATTACCTTTGTGCTGTTCCCTCGTCACACCAATGCCAGTGCTCGAGACAACACCATCAACCTGATCCACACGTTCCGGGACT
ACCTGCACTACCACATCAAGTGCTCTAAGGCCTATATTCACACACGTATGCGGGCGAAAACGTCTGACTTCCTCAAGGTGCTGAACCGCG
CACGCCCAGATGCCGAGAAAAAAGAAATGAAAACAATCACGGGGAAGACGTTTTCATCCCGCTAATCTTGGGAATAAGAGGAGGAAGCGG
CTGGCAACTGAAGGCTGGAACACTTGCTACTGGATAATCGTAGCTTTTAATGTTGCGCCTCTTCAGGTTCTTAAGGGATTCTCCGTTTTG
GTTCCATTTTGTACACGTTTGGAAAATAATCTGCAGAAACGAGCTGTGCTTGCAAAGACTTCATAGTTCCCAAGAATTAAAAAAAAAAAA
AAAAGAATTCCACTTGATCAACTTAATTCCTTTTCTTTATCTTCCCTCCCTCACTTCCCTTTTCTCCCACCCTCTTTTCCAAGCTGTTTC
GCTTTGCAATATATTACTGGTAATGAGTTGCAGGATAATGCAGTCATAACTTGTTTTCTCCTAAGTATTTGAGTTCAAAACTCCTGTATC

>78253_78253_3_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000295701_ARPC2_chr2_219099075_ENST00000295685_length(amino acids)=244AA_BP=18
MWKRAAAAHNMHSLATAALLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHY
RDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASA

--------------------------------------------------------------
>78253_78253_4_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000295701_ARPC2_chr2_219099075_ENST00000315717_length(transcript)=1218nt_BP=104nt
TTTTCCGCTGCAGGGGTGCTGAAGGGGGGACGCGGGTCGGACGCGTCCGGCTGTGGAAGAGAGCGGCGGCCGCTCACAACATGCACAGCC
TGGCGACGGCTGCGTTATTAAAGAGGGTGTACGGGAGTTTCTTGGTAAATCCAGAATCAGGATACAATGTCTCTTTGCTATATGACCTTG
AAAATCTTCCGGCATCCAAGGATTCCATTGTGCATCAAGCTGGCATGTTGAAGCGAAATTGTTTTGCCTCTGTCTTTGAAAAATACTTCC
AATTCCAAGAAGAGGGCAAGGAAGGAGAGAACAGGGCAGTTATCCATTATAGGGATGATGAGACCATGTATGTTGAGTCTAAAAAGGACA
GAGTCACAGTAGTCTTCAGCACAGTGTTTAAGGATGACGACGATGTGGTCATTGGAAAGGTGTTCATGCAGGAGTTCAAAGAAGGACGCA
GAGCCAGCCACACAGCCCCACAGGTCCTCTTTAGCCACAGGGAACCTCCTCTGGAGCTGAAAGACACAGACGCCGCTGTGGGTGACAACA
TTGGCTACATTACCTTTGTGCTGTTCCCTCGTCACACCAATGCCAGTGCTCGAGACAACACCATCAACCTGATCCACACGTTCCGGGACT
ACCTGCACTACCACATCAAGTGCTCTAAGGCCTATATTCACACACGTATGCGGGCGAAAACGTCTGACTTCCTCAAGGTGCTGAACCGCG
CACGCCCAGATGCCGAGAAAAAAGAAATGAAAACAATCACGGGGAAGACGTTTTCATCCCGCTAATCTTGGGAATAAGAGGAGGAAGCGG
CTGGCAACTGAAGGCTGGAACACTTGCTACTGGATAATCGTAGCTTTTAATGTTGCGCCTCTTCAGGTTCTTAAGGGATTCTCCGTTTTG
GTTCCATTTTGTACACGTTTGGAAAATAATCTGCAGAAACGAGCTGTGCTTGCAAAGACTTCATAGTTCCCAAGAATTAAAAAAAAAAAA
AAAAGAATTCCACTTGATCAACTTAATTCCTTTTCTTTATCTTCCCTCCCTCACTTCCCTTTTCTCCCACCCTCTTTTCCAAGCTGTTTC
GCTTTGCAATATATTACTGGTAATGAGTTGCAGGATAATGCAGTCATAACTTGTTTTCTCCTAAGTATTTGAGTTCAAAACTCCTGTATC

>78253_78253_4_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000295701_ARPC2_chr2_219099075_ENST00000315717_length(amino acids)=244AA_BP=18
MWKRAAAAHNMHSLATAALLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHY
RDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASA

--------------------------------------------------------------
>78253_78253_5_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000509807_ARPC2_chr2_219099075_ENST00000295685_length(transcript)=1521nt_BP=399nt
AGTTGTCTTGCCGGGACTGTCCATCTTTTCCCGCCGTTCACTGGCTTTTGGAGGAGGGTCAGAGTTCACGCCGCTCTCTGGAAATAACTG
CTCAAAGCCAGAAGTTGCGGGGACTAGTGGTCGCGGACGTCCTTCCGGTCCTAAATCTTAAGGGGCAAAGGACATACTCTGGGACTGTTA
ACTAGGCCCTGGAGGCGGGAAGAGGATGTGTGGGTGGGGTCAGGGGTGAGAGGTCAGAGGGCCGCGAAGTGGGCGGAGCGAGCCGGAGTC
GGATGGCGGCTACGGCGGCTCATTGTTTTCCGCTGCAGGGGTGCTGAAGGGGGGACGCGGGTCGGACGCGTCCGGCTGTGGAAGAGAGCG
GCGGCCGCTCACAACATGCACAGCCTGGCGACGGCTGCGTTATTAAAGAGGGTGTACGGGAGTTTCTTGGTAAATCCAGAATCAGGATAC
AATGTCTCTTTGCTATATGACCTTGAAAATCTTCCGGCATCCAAGGATTCCATTGTGCATCAAGCTGGCATGTTGAAGCGAAATTGTTTT
GCCTCTGTCTTTGAAAAATACTTCCAATTCCAAGAAGAGGGCAAGGAAGGAGAGAACAGGGCAGTTATCCATTATAGGGATGATGAGACC
ATGTATGTTGAGTCTAAAAAGGACAGAGTCACAGTAGTCTTCAGCACAGTGTTTAAGGATGACGACGATGTGGTCATTGGAAAGGTGTTC
ATGCAGGAGTTCAAAGAAGGACGCAGAGCCAGCCACACAGCCCCACAGGTCCTCTTTAGCCACAGGGAACCTCCTCTGGAGCTGAAAGAC
ACAGACGCCGCTGTGGGTGACAACATTGGCTACATTACCTTTGTGCTGTTCCCTCGTCACACCAATGCCAGTGCTCGAGACAACACCATC
AACCTGATCCACACGTTCCGGGACTACCTGCACTACCACATCAAGTGCTCTAAGGCCTATATTCACACACGTATGCGGGCGAAAACGTCT
GACTTCCTCAAGGTGCTGAACCGCGCACGCCCAGATGCCGAGAAAAAAGAAATGAAAACAATCACGGGGAAGACGTTTTCATCCCGCTAA
TCTTGGGAATAAGAGGAGGAAGCGGCTGGCAACTGAAGGCTGGAACACTTGCTACTGGATAATCGTAGCTTTTAATGTTGCGCCTCTTCA
GGTTCTTAAGGGATTCTCCGTTTTGGTTCCATTTTGTACACGTTTGGAAAATAATCTGCAGAAACGAGCTGTGCTTGCAAAGACTTCATA
GTTCCCAAGAATTAAAAAAAAAAAAAAAAGAATTCCACTTGATCAACTTAATTCCTTTTCTTTATCTTCCCTCCCTCACTTCCCTTTTCT
CCCACCCTCTTTTCCAAGCTGTTTCGCTTTGCAATATATTACTGGTAATGAGTTGCAGGATAATGCAGTCATAACTTGTTTTCTCCTAAG

>78253_78253_5_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000509807_ARPC2_chr2_219099075_ENST00000295685_length(amino acids)=303AA_BP=77
MGLLTRPWRREEDVWVGSGVRGQRAAKWAERAGVGWRLRRLIVFRCRGAEGGTRVGRVRLWKRAAAAHNMHSLATAALLKRVYGSFLVNP
ESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVI
GKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMR

--------------------------------------------------------------
>78253_78253_6_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000509807_ARPC2_chr2_219099075_ENST00000315717_length(transcript)=1513nt_BP=399nt
AGTTGTCTTGCCGGGACTGTCCATCTTTTCCCGCCGTTCACTGGCTTTTGGAGGAGGGTCAGAGTTCACGCCGCTCTCTGGAAATAACTG
CTCAAAGCCAGAAGTTGCGGGGACTAGTGGTCGCGGACGTCCTTCCGGTCCTAAATCTTAAGGGGCAAAGGACATACTCTGGGACTGTTA
ACTAGGCCCTGGAGGCGGGAAGAGGATGTGTGGGTGGGGTCAGGGGTGAGAGGTCAGAGGGCCGCGAAGTGGGCGGAGCGAGCCGGAGTC
GGATGGCGGCTACGGCGGCTCATTGTTTTCCGCTGCAGGGGTGCTGAAGGGGGGACGCGGGTCGGACGCGTCCGGCTGTGGAAGAGAGCG
GCGGCCGCTCACAACATGCACAGCCTGGCGACGGCTGCGTTATTAAAGAGGGTGTACGGGAGTTTCTTGGTAAATCCAGAATCAGGATAC
AATGTCTCTTTGCTATATGACCTTGAAAATCTTCCGGCATCCAAGGATTCCATTGTGCATCAAGCTGGCATGTTGAAGCGAAATTGTTTT
GCCTCTGTCTTTGAAAAATACTTCCAATTCCAAGAAGAGGGCAAGGAAGGAGAGAACAGGGCAGTTATCCATTATAGGGATGATGAGACC
ATGTATGTTGAGTCTAAAAAGGACAGAGTCACAGTAGTCTTCAGCACAGTGTTTAAGGATGACGACGATGTGGTCATTGGAAAGGTGTTC
ATGCAGGAGTTCAAAGAAGGACGCAGAGCCAGCCACACAGCCCCACAGGTCCTCTTTAGCCACAGGGAACCTCCTCTGGAGCTGAAAGAC
ACAGACGCCGCTGTGGGTGACAACATTGGCTACATTACCTTTGTGCTGTTCCCTCGTCACACCAATGCCAGTGCTCGAGACAACACCATC
AACCTGATCCACACGTTCCGGGACTACCTGCACTACCACATCAAGTGCTCTAAGGCCTATATTCACACACGTATGCGGGCGAAAACGTCT
GACTTCCTCAAGGTGCTGAACCGCGCACGCCCAGATGCCGAGAAAAAAGAAATGAAAACAATCACGGGGAAGACGTTTTCATCCCGCTAA
TCTTGGGAATAAGAGGAGGAAGCGGCTGGCAACTGAAGGCTGGAACACTTGCTACTGGATAATCGTAGCTTTTAATGTTGCGCCTCTTCA
GGTTCTTAAGGGATTCTCCGTTTTGGTTCCATTTTGTACACGTTTGGAAAATAATCTGCAGAAACGAGCTGTGCTTGCAAAGACTTCATA
GTTCCCAAGAATTAAAAAAAAAAAAAAAAGAATTCCACTTGATCAACTTAATTCCTTTTCTTTATCTTCCCTCCCTCACTTCCCTTTTCT
CCCACCCTCTTTTCCAAGCTGTTTCGCTTTGCAATATATTACTGGTAATGAGTTGCAGGATAATGCAGTCATAACTTGTTTTCTCCTAAG

>78253_78253_6_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000509807_ARPC2_chr2_219099075_ENST00000315717_length(amino acids)=303AA_BP=77
MGLLTRPWRREEDVWVGSGVRGQRAAKWAERAGVGWRLRRLIVFRCRGAEGGTRVGRVRLWKRAAAAHNMHSLATAALLKRVYGSFLVNP
ESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVI
GKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMR

--------------------------------------------------------------
>78253_78253_7_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000542068_ARPC2_chr2_219099075_ENST00000295685_length(transcript)=1393nt_BP=271nt
GTCCTTCCGGTCCTAAATCTTAAGGGGCAAAGGACATACTCTGGGACTGTTAACTAGGCCCTGGAGGCGGGAAGAGGATGTGTGGGTGGG
GTCAGGGGTGAGAGGTCAGAGGGCCGCGAAGTGGGCGGAGCGAGCCGGAGTCGGATGGCGGCTACGGCGGCTCATTGTTTTCCGCTGCAG
GGGTGCTGAAGGGGGGACGCGGGTCGGACGCGTCCGGCTGTGGAAGAGAGCGGCGGCCGCTCACAACATGCACAGCCTGGCGACGGCTGC
GTTATTAAAGAGGGTGTACGGGAGTTTCTTGGTAAATCCAGAATCAGGATACAATGTCTCTTTGCTATATGACCTTGAAAATCTTCCGGC
ATCCAAGGATTCCATTGTGCATCAAGCTGGCATGTTGAAGCGAAATTGTTTTGCCTCTGTCTTTGAAAAATACTTCCAATTCCAAGAAGA
GGGCAAGGAAGGAGAGAACAGGGCAGTTATCCATTATAGGGATGATGAGACCATGTATGTTGAGTCTAAAAAGGACAGAGTCACAGTAGT
CTTCAGCACAGTGTTTAAGGATGACGACGATGTGGTCATTGGAAAGGTGTTCATGCAGGAGTTCAAAGAAGGACGCAGAGCCAGCCACAC
AGCCCCACAGGTCCTCTTTAGCCACAGGGAACCTCCTCTGGAGCTGAAAGACACAGACGCCGCTGTGGGTGACAACATTGGCTACATTAC
CTTTGTGCTGTTCCCTCGTCACACCAATGCCAGTGCTCGAGACAACACCATCAACCTGATCCACACGTTCCGGGACTACCTGCACTACCA
CATCAAGTGCTCTAAGGCCTATATTCACACACGTATGCGGGCGAAAACGTCTGACTTCCTCAAGGTGCTGAACCGCGCACGCCCAGATGC
CGAGAAAAAAGAAATGAAAACAATCACGGGGAAGACGTTTTCATCCCGCTAATCTTGGGAATAAGAGGAGGAAGCGGCTGGCAACTGAAG
GCTGGAACACTTGCTACTGGATAATCGTAGCTTTTAATGTTGCGCCTCTTCAGGTTCTTAAGGGATTCTCCGTTTTGGTTCCATTTTGTA
CACGTTTGGAAAATAATCTGCAGAAACGAGCTGTGCTTGCAAAGACTTCATAGTTCCCAAGAATTAAAAAAAAAAAAAAAAGAATTCCAC
TTGATCAACTTAATTCCTTTTCTTTATCTTCCCTCCCTCACTTCCCTTTTCTCCCACCCTCTTTTCCAAGCTGTTTCGCTTTGCAATATA
TTACTGGTAATGAGTTGCAGGATAATGCAGTCATAACTTGTTTTCTCCTAAGTATTTGAGTTCAAAACTCCTGTATCTAAAGAAATACGG

>78253_78253_7_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000542068_ARPC2_chr2_219099075_ENST00000295685_length(amino acids)=303AA_BP=77
MGLLTRPWRREEDVWVGSGVRGQRAAKWAERAGVGWRLRRLIVFRCRGAEGGTRVGRVRLWKRAAAAHNMHSLATAALLKRVYGSFLVNP
ESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVI
GKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMR

--------------------------------------------------------------
>78253_78253_8_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000542068_ARPC2_chr2_219099075_ENST00000315717_length(transcript)=1385nt_BP=271nt
GTCCTTCCGGTCCTAAATCTTAAGGGGCAAAGGACATACTCTGGGACTGTTAACTAGGCCCTGGAGGCGGGAAGAGGATGTGTGGGTGGG
GTCAGGGGTGAGAGGTCAGAGGGCCGCGAAGTGGGCGGAGCGAGCCGGAGTCGGATGGCGGCTACGGCGGCTCATTGTTTTCCGCTGCAG
GGGTGCTGAAGGGGGGACGCGGGTCGGACGCGTCCGGCTGTGGAAGAGAGCGGCGGCCGCTCACAACATGCACAGCCTGGCGACGGCTGC
GTTATTAAAGAGGGTGTACGGGAGTTTCTTGGTAAATCCAGAATCAGGATACAATGTCTCTTTGCTATATGACCTTGAAAATCTTCCGGC
ATCCAAGGATTCCATTGTGCATCAAGCTGGCATGTTGAAGCGAAATTGTTTTGCCTCTGTCTTTGAAAAATACTTCCAATTCCAAGAAGA
GGGCAAGGAAGGAGAGAACAGGGCAGTTATCCATTATAGGGATGATGAGACCATGTATGTTGAGTCTAAAAAGGACAGAGTCACAGTAGT
CTTCAGCACAGTGTTTAAGGATGACGACGATGTGGTCATTGGAAAGGTGTTCATGCAGGAGTTCAAAGAAGGACGCAGAGCCAGCCACAC
AGCCCCACAGGTCCTCTTTAGCCACAGGGAACCTCCTCTGGAGCTGAAAGACACAGACGCCGCTGTGGGTGACAACATTGGCTACATTAC
CTTTGTGCTGTTCCCTCGTCACACCAATGCCAGTGCTCGAGACAACACCATCAACCTGATCCACACGTTCCGGGACTACCTGCACTACCA
CATCAAGTGCTCTAAGGCCTATATTCACACACGTATGCGGGCGAAAACGTCTGACTTCCTCAAGGTGCTGAACCGCGCACGCCCAGATGC
CGAGAAAAAAGAAATGAAAACAATCACGGGGAAGACGTTTTCATCCCGCTAATCTTGGGAATAAGAGGAGGAAGCGGCTGGCAACTGAAG
GCTGGAACACTTGCTACTGGATAATCGTAGCTTTTAATGTTGCGCCTCTTCAGGTTCTTAAGGGATTCTCCGTTTTGGTTCCATTTTGTA
CACGTTTGGAAAATAATCTGCAGAAACGAGCTGTGCTTGCAAAGACTTCATAGTTCCCAAGAATTAAAAAAAAAAAAAAAAGAATTCCAC
TTGATCAACTTAATTCCTTTTCTTTATCTTCCCTCCCTCACTTCCCTTTTCTCCCACCCTCTTTTCCAAGCTGTTTCGCTTTGCAATATA
TTACTGGTAATGAGTTGCAGGATAATGCAGTCATAACTTGTTTTCTCCTAAGTATTTGAGTTCAAAACTCCTGTATCTAAAGAAATACGG

>78253_78253_8_RQCD1-ARPC2_RQCD1_chr2_219433701_ENST00000542068_ARPC2_chr2_219099075_ENST00000315717_length(amino acids)=303AA_BP=77
MGLLTRPWRREEDVWVGSGVRGQRAAKWAERAGVGWRLRRLIVFRCRGAEGGTRVGRVRLWKRAAAAHNMHSLATAALLKRVYGSFLVNP
ESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVI
GKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RQCD1-ARPC2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RQCD1-ARPC2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RQCD1-ARPC2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource