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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:RREB1-KIF13A (FusionGDB2 ID:78302)

Fusion Gene Summary for RREB1-KIF13A

check button Fusion gene summary
Fusion gene informationFusion gene name: RREB1-KIF13A
Fusion gene ID: 78302
HgeneTgene
Gene symbol

RREB1

KIF13A

Gene ID

6239

63971

Gene nameras responsive element binding protein 1kinesin family member 13A
SynonymsFINB|HNT|LZ321|RREB-1|Zep-1RBKIN|bA500C11.2
Cytomap

6p24.3

6p22.3

Type of geneprotein-codingprotein-coding
Descriptionras-responsive element-binding protein 1DNA-binding proteinfinger protein in nuclear bodieshindsight homolograf-responsive zinc finger protein LZ321zinc finger motif enhancer-binding protein 1kinesin-like protein KIF13Ahomolog of mouse KIF13A mannose-6-phosphate receptor transporterkinesin-like protein RBKIN
Modification date2020031320200313
UniProtAcc.

Q9H1H9

Ensembl transtripts involved in fusion geneENST00000334984, ENST00000349384, 
ENST00000379933, ENST00000379938, 
ENST00000502704, ENST00000503342, 
ENST00000259711, ENST00000378814, 
ENST00000378826, ENST00000378816, 
ENST00000378843, 
Fusion gene scores* DoF score17 X 12 X 9=18368 X 8 X 5=320
# samples 178
** MAII scorelog2(17/1836*10)=-3.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/320*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RREB1 [Title/Abstract] AND KIF13A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRREB1(7189555)-KIF13A(17765177), # samples:1
Anticipated loss of major functional domain due to fusion event.RREB1-KIF13A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
RREB1-KIF13A seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
RREB1-KIF13A seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
RREB1-KIF13A seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRREB1

GO:0045944

positive regulation of transcription by RNA polymerase II

8816445


check buttonFusion gene breakpoints across RREB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KIF13A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4THCATCGA-ET-A39S-01ARREB1chr6

7189555

+KIF13Achr6

17765177

-


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Fusion Gene ORF analysis for RREB1-KIF13A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000334984ENST00000502704RREB1chr6

7189555

+KIF13Achr6

17765177

-
5CDS-intronENST00000334984ENST00000503342RREB1chr6

7189555

+KIF13Achr6

17765177

-
5CDS-intronENST00000349384ENST00000502704RREB1chr6

7189555

+KIF13Achr6

17765177

-
5CDS-intronENST00000349384ENST00000503342RREB1chr6

7189555

+KIF13Achr6

17765177

-
5CDS-intronENST00000379933ENST00000502704RREB1chr6

7189555

+KIF13Achr6

17765177

-
5CDS-intronENST00000379933ENST00000503342RREB1chr6

7189555

+KIF13Achr6

17765177

-
5CDS-intronENST00000379938ENST00000502704RREB1chr6

7189555

+KIF13Achr6

17765177

-
5CDS-intronENST00000379938ENST00000503342RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000334984ENST00000259711RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000334984ENST00000378814RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000334984ENST00000378826RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000349384ENST00000259711RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000349384ENST00000378814RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000349384ENST00000378826RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000379933ENST00000259711RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000379933ENST00000378814RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000379933ENST00000378826RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000379938ENST00000259711RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000379938ENST00000378814RREB1chr6

7189555

+KIF13Achr6

17765177

-
Frame-shiftENST00000379938ENST00000378826RREB1chr6

7189555

+KIF13Achr6

17765177

-
In-frameENST00000334984ENST00000378816RREB1chr6

7189555

+KIF13Achr6

17765177

-
In-frameENST00000334984ENST00000378843RREB1chr6

7189555

+KIF13Achr6

17765177

-
In-frameENST00000349384ENST00000378816RREB1chr6

7189555

+KIF13Achr6

17765177

-
In-frameENST00000349384ENST00000378843RREB1chr6

7189555

+KIF13Achr6

17765177

-
In-frameENST00000379933ENST00000378816RREB1chr6

7189555

+KIF13Achr6

17765177

-
In-frameENST00000379933ENST00000378843RREB1chr6

7189555

+KIF13Achr6

17765177

-
In-frameENST00000379938ENST00000378816RREB1chr6

7189555

+KIF13Achr6

17765177

-
In-frameENST00000379938ENST00000378843RREB1chr6

7189555

+KIF13Achr6

17765177

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000379933RREB1chr67189555+ENST00000378843KIF13Achr617765177-21338816771717346
ENST00000379933RREB1chr67189555+ENST00000378816KIF13Achr617765177-21318816771717346
ENST00000379938RREB1chr67189555+ENST00000378843KIF13Achr617765177-22149627581798346
ENST00000379938RREB1chr67189555+ENST00000378816KIF13Achr617765177-22129627581798346
ENST00000334984RREB1chr67189555+ENST00000378843KIF13Achr617765177-19917395351575346
ENST00000334984RREB1chr67189555+ENST00000378816KIF13Achr617765177-19897395351575346
ENST00000349384RREB1chr67189555+ENST00000378843KIF13Achr617765177-19917395351575346
ENST00000349384RREB1chr67189555+ENST00000378816KIF13Achr617765177-19897395351575346

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000379933ENST00000378843RREB1chr67189555+KIF13Achr617765177-0.0045543840.9954456
ENST00000379933ENST00000378816RREB1chr67189555+KIF13Achr617765177-0.004521960.9954781
ENST00000379938ENST00000378843RREB1chr67189555+KIF13Achr617765177-0.0045061630.99549377
ENST00000379938ENST00000378816RREB1chr67189555+KIF13Achr617765177-0.0044931940.99550676
ENST00000334984ENST00000378843RREB1chr67189555+KIF13Achr617765177-0.0045220460.995478
ENST00000334984ENST00000378816RREB1chr67189555+KIF13Achr617765177-0.0044753090.99552476
ENST00000349384ENST00000378843RREB1chr67189555+KIF13Achr617765177-0.0045220460.995478
ENST00000349384ENST00000378816RREB1chr67189555+KIF13Achr617765177-0.0044753090.99552476

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Fusion Genomic Features for RREB1-KIF13A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RREB1-KIF13A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:7189555/chr6:17765177)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.KIF13A

Q9H1H9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis. {ECO:0000269|PubMed:19841138, ECO:0000269|PubMed:20208530}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+61266_881411477.0Zinc fingerC2H2-type 1
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+61297_1191411477.0Zinc fingerC2H2-type 2
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+61266_881411688.0Zinc fingerC2H2-type 1
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+61297_1191411688.0Zinc fingerC2H2-type 2
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+61266_881411688.0Zinc fingerC2H2-type 1
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+61297_1191411688.0Zinc fingerC2H2-type 2
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+61366_881411743.0Zinc fingerC2H2-type 1
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+61397_1191411743.0Zinc fingerC2H2-type 2
TgeneKIF13Achr6:7189555chr6:17765177ENST0000037881435381518_154714791750.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST0000037882636381518_154714921771.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST0000037884335371518_154714791758.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST00000502704031100_1138071.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST00000502704031518_1547071.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST0000050270403359_436071.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST0000050270403602_775071.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST0000050270403469_519071.0DomainNote=FHA
TgeneKIF13Achr6:7189555chr6:17765177ENST00000502704035_352071.0DomainKinesin motor
TgeneKIF13Achr6:7189555chr6:17765177ENST0000050270403102_109071.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612481_5461411477.0Compositional biasNote=Pro-rich
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612877_8801411477.0Compositional biasNote=Poly-Pro
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612969_10641411477.0Compositional biasNote=Pro-rich
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612481_5461411688.0Compositional biasNote=Pro-rich
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612877_8801411688.0Compositional biasNote=Poly-Pro
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612969_10641411688.0Compositional biasNote=Pro-rich
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612481_5461411688.0Compositional biasNote=Pro-rich
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612877_8801411688.0Compositional biasNote=Poly-Pro
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612969_10641411688.0Compositional biasNote=Pro-rich
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613481_5461411743.0Compositional biasNote=Pro-rich
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613877_8801411743.0Compositional biasNote=Poly-Pro
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613969_10641411743.0Compositional biasNote=Pro-rich
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+6121246_12681411477.0Zinc fingerC2H2-type 12
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612125_1471411477.0Zinc fingerC2H2-type 3
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+6121393_14151411477.0Zinc fingerC2H2-type 13
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+6121512_15341411477.0Zinc fingerC2H2-type 14
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+6121540_15621411477.0Zinc fingerC2H2-type 15
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612208_2301411477.0Zinc fingerC2H2-type 4
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612235_2581411477.0Zinc fingerC2H2-type 5
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612316_3381411477.0Zinc fingerC2H2-type 6
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612643_6651411477.0Zinc fingerC2H2-type 7
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612671_6931411477.0Zinc fingerC2H2-type 8
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612699_7221411477.0Zinc fingerC2H2-type 9
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612753_7751411477.0Zinc fingerC2H2-type 10
HgeneRREB1chr6:7189555chr6:17765177ENST00000334984+612790_8151411477.0Zinc fingerC2H2-type 11
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+6121246_12681411688.0Zinc fingerC2H2-type 12
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612125_1471411688.0Zinc fingerC2H2-type 3
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+6121393_14151411688.0Zinc fingerC2H2-type 13
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+6121512_15341411688.0Zinc fingerC2H2-type 14
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+6121540_15621411688.0Zinc fingerC2H2-type 15
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612208_2301411688.0Zinc fingerC2H2-type 4
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612235_2581411688.0Zinc fingerC2H2-type 5
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612316_3381411688.0Zinc fingerC2H2-type 6
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612643_6651411688.0Zinc fingerC2H2-type 7
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612671_6931411688.0Zinc fingerC2H2-type 8
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612699_7221411688.0Zinc fingerC2H2-type 9
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612753_7751411688.0Zinc fingerC2H2-type 10
HgeneRREB1chr6:7189555chr6:17765177ENST00000349384+612790_8151411688.0Zinc fingerC2H2-type 11
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+6121246_12681411688.0Zinc fingerC2H2-type 12
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612125_1471411688.0Zinc fingerC2H2-type 3
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+6121393_14151411688.0Zinc fingerC2H2-type 13
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+6121512_15341411688.0Zinc fingerC2H2-type 14
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+6121540_15621411688.0Zinc fingerC2H2-type 15
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612208_2301411688.0Zinc fingerC2H2-type 4
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612235_2581411688.0Zinc fingerC2H2-type 5
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612316_3381411688.0Zinc fingerC2H2-type 6
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612643_6651411688.0Zinc fingerC2H2-type 7
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612671_6931411688.0Zinc fingerC2H2-type 8
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612699_7221411688.0Zinc fingerC2H2-type 9
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612753_7751411688.0Zinc fingerC2H2-type 10
HgeneRREB1chr6:7189555chr6:17765177ENST00000379933+612790_8151411688.0Zinc fingerC2H2-type 11
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+6131246_12681411743.0Zinc fingerC2H2-type 12
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613125_1471411743.0Zinc fingerC2H2-type 3
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+6131393_14151411743.0Zinc fingerC2H2-type 13
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+6131512_15341411743.0Zinc fingerC2H2-type 14
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+6131540_15621411743.0Zinc fingerC2H2-type 15
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613208_2301411743.0Zinc fingerC2H2-type 4
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613235_2581411743.0Zinc fingerC2H2-type 5
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613316_3381411743.0Zinc fingerC2H2-type 6
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613643_6651411743.0Zinc fingerC2H2-type 7
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613671_6931411743.0Zinc fingerC2H2-type 8
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613699_7221411743.0Zinc fingerC2H2-type 9
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613753_7751411743.0Zinc fingerC2H2-type 10
HgeneRREB1chr6:7189555chr6:17765177ENST00000379938+613790_8151411743.0Zinc fingerC2H2-type 11
TgeneKIF13Achr6:7189555chr6:17765177ENST0000025971137391100_113815271806.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST0000025971137391518_154715271806.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST000002597113739359_43615271806.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST000002597113739602_77515271806.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST0000037881435381100_113814791750.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788143538359_43614791750.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788143538602_77514791750.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST0000037882636381100_113814921771.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788263638359_43614921771.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788263638602_77514921771.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST0000037884335371100_113814791758.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788433537359_43614791758.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788433537602_77514791758.0Coiled coilOntology_term=ECO:0000255
TgeneKIF13Achr6:7189555chr6:17765177ENST000002597113739469_51915271806.0DomainNote=FHA
TgeneKIF13Achr6:7189555chr6:17765177ENST0000025971137395_35215271806.0DomainKinesin motor
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788143538469_51914791750.0DomainNote=FHA
TgeneKIF13Achr6:7189555chr6:17765177ENST0000037881435385_35214791750.0DomainKinesin motor
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788263638469_51914921771.0DomainNote=FHA
TgeneKIF13Achr6:7189555chr6:17765177ENST0000037882636385_35214921771.0DomainKinesin motor
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788433537469_51914791758.0DomainNote=FHA
TgeneKIF13Achr6:7189555chr6:17765177ENST0000037884335375_35214791758.0DomainKinesin motor
TgeneKIF13Achr6:7189555chr6:17765177ENST000002597113739102_10915271806.0Nucleotide bindingATP
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788143538102_10914791750.0Nucleotide bindingATP
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788263638102_10914921771.0Nucleotide bindingATP
TgeneKIF13Achr6:7189555chr6:17765177ENST000003788433537102_10914791758.0Nucleotide bindingATP


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Fusion Gene Sequence for RREB1-KIF13A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>78302_78302_1_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000334984_KIF13A_chr6_17765177_ENST00000378816_length(transcript)=1989nt_BP=739nt
ATGCCAGGGAGCCAAGCGTCCTGCCCGGCCGTTGCTCCGACTGTGTGTTCCAGGAGTGGTGGCTCTGAGGTGTGACCCTGCCCACGTTTG
GGCCCAGCCAGGTTCAGCCCCCCAATAAGGAGGGCAGCTTGATAACACAAAGAAAACAGTGTCAACGAGTACTACCAAGAGAAGAAGACA
AGAGGTCAACACAGACTCATTTTCTACTCCGTGTGAATGATAGCTACAGCAGGGGAAAGTTTCATAGTCTATCAGTGGGTCAGAAAATGG
AGTTTTATAGCAGAGGCTTCTTAGAAGCTTAAACCCCTGTCCCAATGACGTCAAGTTCGCCCGCTGGCTTGGAAGGTTCAGACCTATCTT
CCATCAACACCATGATGTCGGCGGTCATGAGTGTAGGGAAGGTCACAGAGAATGGCGGGAGCCCCCAGGGGATCAAGTCCCCCTCGAAGC
CTCCAGGACCAAATCGGATTGGCAGAAGGAACCAGGAAACGAAAGAGGAGAAGTCTTCCTATAACTGCCCCCTGTGTGAGAAGATTTGCA
CTACCCAGCACCAGCTGACCATGCACATTCGCCAGCACAACACAGACACTGGAGGAGCCGACCACTCATGCAGCATCTGCGGAAAGTCAC
TGAGCTCGGCCAGCTCCCTCGATCGCCACATGCTGGTGCACTCTGGCGAGAGGCCTTACAAGTGCACTGTGTGTGGCCAGTCATTTACCA
CCAATGGGAACATGCACAGGACTCTGAGGAGGAAGAAAATGAGCTGGAAGCTATTAACAGGAAGCTAATAAGTTCACAGCCTTATGTACC
TGTGGAGTTTGCTGACTTCAGTGTTTACAATGCCAGCTTGGAGAACAGGGAATGGTTTTCCTCTAAAGTAGATCTGTCAAACTCACGGGT
CTTGGAGAAAGAAGTGTCCCGTAGCCCTACCACCAGCAGTATTACCAGTGGCTACTTTTCCCACAGTGCCTCCAATGCCACCCTGTCTGA
CATGGTGGTCCCTTCTAGTGACAGCTCAGACCAGCTGGCCATTCAGACGAAGGATGCAGACTCCACCGAGCACTCCACACCATCGCTTGT
GCATGATTTCAGGCCGTCCTCAAACAAAGAGTTGACAGAAGTCGAAAAAGGCTTGGTAAAGGACAAGATAATTGTGGTGCCACTCAAGGA
AAACAGTGCCTTAGCCAAAGGGAGCCCATCATCCCAGAGCATCCCTGAGAAAAACTCCAAATCACTGTGCAGGACTGGCTCATGTTCAGA
ACTAGATGCCTGCCCCAGCAAAATTAGCCAGCCAGCCAGGGGATTCTGCCCCAGGGAGGTGACGGTAGAACACACCACCAACATCCTTGA
AGACCATTCTTTCACAGAATTTATGGGAGTGTCAGAGGGAAAAGATTTTGATGGTTTGACAGATTCTTCTGCTGGAGAGCTTTCCAGTAG
GAGGAGTCTACCAAATAAAACAGGCGGCAAGACTGTCTCCGATGGGCTCCACCACCCCAGCCAGCTGCATTCCAAGTTAGAGAATGACCA
GGTAATAATTCCAGAGGCAGCCTTTTGGGTTCTGTGCTGTCAATGAGTATGTCTAACTGTATGTCAACCCCAGAGGCCCTTCACCGCAAC
AACTTGGTAGGAAAGATTCATCCAGTTGTTTGTGACAGCAAAGATGAGCCCACAGAGAAGCAGGCTCACTTCCTGCACAGCTGTCTCTGT
CGGAGAGCAAGTCTGTTTTGGGAACTAGAACGCAATTGTGAAATTATAAGACCAGTGGATTTTTTTACCTGGCACATGGGTTGGTGTTGA
ATGAAGTGTTCAGATGGATAAGGATCAATCTCATATTCATTCCCTGGGATGTTTAGTTACCAGTTTTCCCAAAGTGTTCTGGTAGCATCT
ACCATATTTCATCAAATCTGTGATTCCTTTGATTATTATATGAACCATTATTTTATGTATCATTAAGAAAAAATACTGCCAATTAAACTC

>78302_78302_1_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000334984_KIF13A_chr6_17765177_ENST00000378816_length(amino acids)=346AA_BP=68
MHYPAPADHAHSPAQHRHWRSRPLMQHLRKVTELGQLPRSPHAGALWREALQVHCVWPVIYHQWEHAQDSEEEENELEAINRKLISSQPY
VPVEFADFSVYNASLENREWFSSKVDLSNSRVLEKEVSRSPTTSSITSGYFSHSASNATLSDMVVPSSDSSDQLAIQTKDADSTEHSTPS
LVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSPSSQSIPEKNSKSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNI

--------------------------------------------------------------
>78302_78302_2_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000334984_KIF13A_chr6_17765177_ENST00000378843_length(transcript)=1991nt_BP=739nt
ATGCCAGGGAGCCAAGCGTCCTGCCCGGCCGTTGCTCCGACTGTGTGTTCCAGGAGTGGTGGCTCTGAGGTGTGACCCTGCCCACGTTTG
GGCCCAGCCAGGTTCAGCCCCCCAATAAGGAGGGCAGCTTGATAACACAAAGAAAACAGTGTCAACGAGTACTACCAAGAGAAGAAGACA
AGAGGTCAACACAGACTCATTTTCTACTCCGTGTGAATGATAGCTACAGCAGGGGAAAGTTTCATAGTCTATCAGTGGGTCAGAAAATGG
AGTTTTATAGCAGAGGCTTCTTAGAAGCTTAAACCCCTGTCCCAATGACGTCAAGTTCGCCCGCTGGCTTGGAAGGTTCAGACCTATCTT
CCATCAACACCATGATGTCGGCGGTCATGAGTGTAGGGAAGGTCACAGAGAATGGCGGGAGCCCCCAGGGGATCAAGTCCCCCTCGAAGC
CTCCAGGACCAAATCGGATTGGCAGAAGGAACCAGGAAACGAAAGAGGAGAAGTCTTCCTATAACTGCCCCCTGTGTGAGAAGATTTGCA
CTACCCAGCACCAGCTGACCATGCACATTCGCCAGCACAACACAGACACTGGAGGAGCCGACCACTCATGCAGCATCTGCGGAAAGTCAC
TGAGCTCGGCCAGCTCCCTCGATCGCCACATGCTGGTGCACTCTGGCGAGAGGCCTTACAAGTGCACTGTGTGTGGCCAGTCATTTACCA
CCAATGGGAACATGCACAGGACTCTGAGGAGGAAGAAAATGAGCTGGAAGCTATTAACAGGAAGCTAATAAGTTCACAGCCTTATGTACC
TGTGGAGTTTGCTGACTTCAGTGTTTACAATGCCAGCTTGGAGAACAGGGAATGGTTTTCCTCTAAAGTAGATCTGTCAAACTCACGGGT
CTTGGAGAAAGAAGTGTCCCGTAGCCCTACCACCAGCAGTATTACCAGTGGCTACTTTTCCCACAGTGCCTCCAATGCCACCCTGTCTGA
CATGGTGGTCCCTTCTAGTGACAGCTCAGACCAGCTGGCCATTCAGACGAAGGATGCAGACTCCACCGAGCACTCCACACCATCGCTTGT
GCATGATTTCAGGCCGTCCTCAAACAAAGAGTTGACAGAAGTCGAAAAAGGCTTGGTAAAGGACAAGATAATTGTGGTGCCACTCAAGGA
AAACAGTGCCTTAGCCAAAGGGAGCCCATCATCCCAGAGCATCCCTGAGAAAAACTCCAAATCACTGTGCAGGACTGGCTCATGTTCAGA
ACTAGATGCCTGCCCCAGCAAAATTAGCCAGCCAGCCAGGGGATTCTGCCCCAGGGAGGTGACGGTAGAACACACCACCAACATCCTTGA
AGACCATTCTTTCACAGAATTTATGGGAGTGTCAGAGGGAAAAGATTTTGATGGTTTGACAGATTCTTCTGCTGGAGAGCTTTCCAGTAG
GAGGAGTCTACCAAATAAAACAGGCGGCAAGACTGTCTCCGATGGGCTCCACCACCCCAGCCAGCTGCATTCCAAGTTAGAGAATGACCA
GGTAATAATTCCAGAGGCAGCCTTTTGGGTTCTGTGCTGTCAATGAGTATGTCTAACTGTATGTCAACCCCAGAGGCCCTTCACCGCAAC
AACTTGGTAGGAAAGATTCATCCAGTTGTTTGTGACAGCAAAGATGAGCCCACAGAGAAGCAGGCTCACTTCCTGCACAGCTGTCTCTGT
CGGAGAGCAAGTCTGTTTTGGGAACTAGAACGCAATTGTGAAATTATAAGACCAGTGGATTTTTTTACCTGGCACATGGGTTGGTGTTGA
ATGAAGTGTTCAGATGGATAAGGATCAATCTCATATTCATTCCCTGGGATGTTTAGTTACCAGTTTTCCCAAAGTGTTCTGGTAGCATCT
ACCATATTTCATCAAATCTGTGATTCCTTTGATTATTATATGAACCATTATTTTATGTATCATTAAGAAAAAATACTGCCAATTAAACTC

>78302_78302_2_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000334984_KIF13A_chr6_17765177_ENST00000378843_length(amino acids)=346AA_BP=68
MHYPAPADHAHSPAQHRHWRSRPLMQHLRKVTELGQLPRSPHAGALWREALQVHCVWPVIYHQWEHAQDSEEEENELEAINRKLISSQPY
VPVEFADFSVYNASLENREWFSSKVDLSNSRVLEKEVSRSPTTSSITSGYFSHSASNATLSDMVVPSSDSSDQLAIQTKDADSTEHSTPS
LVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSPSSQSIPEKNSKSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNI

--------------------------------------------------------------
>78302_78302_3_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000349384_KIF13A_chr6_17765177_ENST00000378816_length(transcript)=1989nt_BP=739nt
ATGCCAGGGAGCCAAGCGTCCTGCCCGGCCGTTGCTCCGACTGTGTGTTCCAGGAGTGGTGGCTCTGAGGTGTGACCCTGCCCACGTTTG
GGCCCAGCCAGGTTCAGCCCCCCAATAAGGAGGGCAGCTTGATAACACAAAGAAAACAGTGTCAACGAGTACTACCAAGAGAAGAAGACA
AGAGGTCAACACAGACTCATTTTCTACTCCGTGTGAATGATAGCTACAGCAGGGGAAAGTTTCATAGTCTATCAGTGGGTCAGAAAATGG
AGTTTTATAGCAGAGGCTTCTTAGAAGCTTAAACCCCTGTCCCAATGACGTCAAGTTCGCCCGCTGGCTTGGAAGGTTCAGACCTATCTT
CCATCAACACCATGATGTCGGCGGTCATGAGTGTAGGGAAGGTCACAGAGAATGGCGGGAGCCCCCAGGGGATCAAGTCCCCCTCGAAGC
CTCCAGGACCAAATCGGATTGGCAGAAGGAACCAGGAAACGAAAGAGGAGAAGTCTTCCTATAACTGCCCCCTGTGTGAGAAGATTTGCA
CTACCCAGCACCAGCTGACCATGCACATTCGCCAGCACAACACAGACACTGGAGGAGCCGACCACTCATGCAGCATCTGCGGAAAGTCAC
TGAGCTCGGCCAGCTCCCTCGATCGCCACATGCTGGTGCACTCTGGCGAGAGGCCTTACAAGTGCACTGTGTGTGGCCAGTCATTTACCA
CCAATGGGAACATGCACAGGACTCTGAGGAGGAAGAAAATGAGCTGGAAGCTATTAACAGGAAGCTAATAAGTTCACAGCCTTATGTACC
TGTGGAGTTTGCTGACTTCAGTGTTTACAATGCCAGCTTGGAGAACAGGGAATGGTTTTCCTCTAAAGTAGATCTGTCAAACTCACGGGT
CTTGGAGAAAGAAGTGTCCCGTAGCCCTACCACCAGCAGTATTACCAGTGGCTACTTTTCCCACAGTGCCTCCAATGCCACCCTGTCTGA
CATGGTGGTCCCTTCTAGTGACAGCTCAGACCAGCTGGCCATTCAGACGAAGGATGCAGACTCCACCGAGCACTCCACACCATCGCTTGT
GCATGATTTCAGGCCGTCCTCAAACAAAGAGTTGACAGAAGTCGAAAAAGGCTTGGTAAAGGACAAGATAATTGTGGTGCCACTCAAGGA
AAACAGTGCCTTAGCCAAAGGGAGCCCATCATCCCAGAGCATCCCTGAGAAAAACTCCAAATCACTGTGCAGGACTGGCTCATGTTCAGA
ACTAGATGCCTGCCCCAGCAAAATTAGCCAGCCAGCCAGGGGATTCTGCCCCAGGGAGGTGACGGTAGAACACACCACCAACATCCTTGA
AGACCATTCTTTCACAGAATTTATGGGAGTGTCAGAGGGAAAAGATTTTGATGGTTTGACAGATTCTTCTGCTGGAGAGCTTTCCAGTAG
GAGGAGTCTACCAAATAAAACAGGCGGCAAGACTGTCTCCGATGGGCTCCACCACCCCAGCCAGCTGCATTCCAAGTTAGAGAATGACCA
GGTAATAATTCCAGAGGCAGCCTTTTGGGTTCTGTGCTGTCAATGAGTATGTCTAACTGTATGTCAACCCCAGAGGCCCTTCACCGCAAC
AACTTGGTAGGAAAGATTCATCCAGTTGTTTGTGACAGCAAAGATGAGCCCACAGAGAAGCAGGCTCACTTCCTGCACAGCTGTCTCTGT
CGGAGAGCAAGTCTGTTTTGGGAACTAGAACGCAATTGTGAAATTATAAGACCAGTGGATTTTTTTACCTGGCACATGGGTTGGTGTTGA
ATGAAGTGTTCAGATGGATAAGGATCAATCTCATATTCATTCCCTGGGATGTTTAGTTACCAGTTTTCCCAAAGTGTTCTGGTAGCATCT
ACCATATTTCATCAAATCTGTGATTCCTTTGATTATTATATGAACCATTATTTTATGTATCATTAAGAAAAAATACTGCCAATTAAACTC

>78302_78302_3_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000349384_KIF13A_chr6_17765177_ENST00000378816_length(amino acids)=346AA_BP=68
MHYPAPADHAHSPAQHRHWRSRPLMQHLRKVTELGQLPRSPHAGALWREALQVHCVWPVIYHQWEHAQDSEEEENELEAINRKLISSQPY
VPVEFADFSVYNASLENREWFSSKVDLSNSRVLEKEVSRSPTTSSITSGYFSHSASNATLSDMVVPSSDSSDQLAIQTKDADSTEHSTPS
LVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSPSSQSIPEKNSKSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNI

--------------------------------------------------------------
>78302_78302_4_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000349384_KIF13A_chr6_17765177_ENST00000378843_length(transcript)=1991nt_BP=739nt
ATGCCAGGGAGCCAAGCGTCCTGCCCGGCCGTTGCTCCGACTGTGTGTTCCAGGAGTGGTGGCTCTGAGGTGTGACCCTGCCCACGTTTG
GGCCCAGCCAGGTTCAGCCCCCCAATAAGGAGGGCAGCTTGATAACACAAAGAAAACAGTGTCAACGAGTACTACCAAGAGAAGAAGACA
AGAGGTCAACACAGACTCATTTTCTACTCCGTGTGAATGATAGCTACAGCAGGGGAAAGTTTCATAGTCTATCAGTGGGTCAGAAAATGG
AGTTTTATAGCAGAGGCTTCTTAGAAGCTTAAACCCCTGTCCCAATGACGTCAAGTTCGCCCGCTGGCTTGGAAGGTTCAGACCTATCTT
CCATCAACACCATGATGTCGGCGGTCATGAGTGTAGGGAAGGTCACAGAGAATGGCGGGAGCCCCCAGGGGATCAAGTCCCCCTCGAAGC
CTCCAGGACCAAATCGGATTGGCAGAAGGAACCAGGAAACGAAAGAGGAGAAGTCTTCCTATAACTGCCCCCTGTGTGAGAAGATTTGCA
CTACCCAGCACCAGCTGACCATGCACATTCGCCAGCACAACACAGACACTGGAGGAGCCGACCACTCATGCAGCATCTGCGGAAAGTCAC
TGAGCTCGGCCAGCTCCCTCGATCGCCACATGCTGGTGCACTCTGGCGAGAGGCCTTACAAGTGCACTGTGTGTGGCCAGTCATTTACCA
CCAATGGGAACATGCACAGGACTCTGAGGAGGAAGAAAATGAGCTGGAAGCTATTAACAGGAAGCTAATAAGTTCACAGCCTTATGTACC
TGTGGAGTTTGCTGACTTCAGTGTTTACAATGCCAGCTTGGAGAACAGGGAATGGTTTTCCTCTAAAGTAGATCTGTCAAACTCACGGGT
CTTGGAGAAAGAAGTGTCCCGTAGCCCTACCACCAGCAGTATTACCAGTGGCTACTTTTCCCACAGTGCCTCCAATGCCACCCTGTCTGA
CATGGTGGTCCCTTCTAGTGACAGCTCAGACCAGCTGGCCATTCAGACGAAGGATGCAGACTCCACCGAGCACTCCACACCATCGCTTGT
GCATGATTTCAGGCCGTCCTCAAACAAAGAGTTGACAGAAGTCGAAAAAGGCTTGGTAAAGGACAAGATAATTGTGGTGCCACTCAAGGA
AAACAGTGCCTTAGCCAAAGGGAGCCCATCATCCCAGAGCATCCCTGAGAAAAACTCCAAATCACTGTGCAGGACTGGCTCATGTTCAGA
ACTAGATGCCTGCCCCAGCAAAATTAGCCAGCCAGCCAGGGGATTCTGCCCCAGGGAGGTGACGGTAGAACACACCACCAACATCCTTGA
AGACCATTCTTTCACAGAATTTATGGGAGTGTCAGAGGGAAAAGATTTTGATGGTTTGACAGATTCTTCTGCTGGAGAGCTTTCCAGTAG
GAGGAGTCTACCAAATAAAACAGGCGGCAAGACTGTCTCCGATGGGCTCCACCACCCCAGCCAGCTGCATTCCAAGTTAGAGAATGACCA
GGTAATAATTCCAGAGGCAGCCTTTTGGGTTCTGTGCTGTCAATGAGTATGTCTAACTGTATGTCAACCCCAGAGGCCCTTCACCGCAAC
AACTTGGTAGGAAAGATTCATCCAGTTGTTTGTGACAGCAAAGATGAGCCCACAGAGAAGCAGGCTCACTTCCTGCACAGCTGTCTCTGT
CGGAGAGCAAGTCTGTTTTGGGAACTAGAACGCAATTGTGAAATTATAAGACCAGTGGATTTTTTTACCTGGCACATGGGTTGGTGTTGA
ATGAAGTGTTCAGATGGATAAGGATCAATCTCATATTCATTCCCTGGGATGTTTAGTTACCAGTTTTCCCAAAGTGTTCTGGTAGCATCT
ACCATATTTCATCAAATCTGTGATTCCTTTGATTATTATATGAACCATTATTTTATGTATCATTAAGAAAAAATACTGCCAATTAAACTC

>78302_78302_4_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000349384_KIF13A_chr6_17765177_ENST00000378843_length(amino acids)=346AA_BP=68
MHYPAPADHAHSPAQHRHWRSRPLMQHLRKVTELGQLPRSPHAGALWREALQVHCVWPVIYHQWEHAQDSEEEENELEAINRKLISSQPY
VPVEFADFSVYNASLENREWFSSKVDLSNSRVLEKEVSRSPTTSSITSGYFSHSASNATLSDMVVPSSDSSDQLAIQTKDADSTEHSTPS
LVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSPSSQSIPEKNSKSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNI

--------------------------------------------------------------
>78302_78302_5_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000379933_KIF13A_chr6_17765177_ENST00000378816_length(transcript)=2131nt_BP=881nt
CGGGATGGCAACTGCGGTCACCCTGCTAAAGTCGGGGCGGGGGCGGCGGTCCTCCCCCTCACCCCCCCCAGTCCGAGCGCCGCCGCCGCC
GCCGCCGCCGCCGCCGCGGCCGCTCAGTAACACGTCCCCAGGAGACTCGCAGGAGCAACACGTGATGTGTCTACTTATCAGGGTTGCTCC
GACTGTGTGTTCCAGGAGTGGTGGCTCTGAGGTGTGACCCTGCCCACGTTTGGGCCCAGCCAGGTTCAGCCCCCCAATAAGGAGGGCAGC
TTGATAACACAAAGAAAACAGTGTCAACGAGTACTACCAAGAGAAGAAGACAAGAGGTCAACACAGACTCATTTTCTACTCCGTGTGAAT
GATAGCTACAGCAGGGGAAAGTTTCATAGTCTATCAGTGGGTCAGAAAATGGAGTTTTATAGCAGAGGCTTCTTAGAAGCTTAAACCCCT
GTCCCAATGACGTCAAGTTCGCCCGCTGGCTTGGAAGGTTCAGACCTATCTTCCATCAACACCATGATGTCGGCGGTCATGAGTGTAGGG
AAGGTCACAGAGAATGGCGGGAGCCCCCAGGGGATCAAGTCCCCCTCGAAGCCTCCAGGACCAAATCGGATTGGCAGAAGGAACCAGGAA
ACGAAAGAGGAGAAGTCTTCCTATAACTGCCCCCTGTGTGAGAAGATTTGCACTACCCAGCACCAGCTGACCATGCACATTCGCCAGCAC
AACACAGACACTGGAGGAGCCGACCACTCATGCAGCATCTGCGGAAAGTCACTGAGCTCGGCCAGCTCCCTCGATCGCCACATGCTGGTG
CACTCTGGCGAGAGGCCTTACAAGTGCACTGTGTGTGGCCAGTCATTTACCACCAATGGGAACATGCACAGGACTCTGAGGAGGAAGAAA
ATGAGCTGGAAGCTATTAACAGGAAGCTAATAAGTTCACAGCCTTATGTACCTGTGGAGTTTGCTGACTTCAGTGTTTACAATGCCAGCT
TGGAGAACAGGGAATGGTTTTCCTCTAAAGTAGATCTGTCAAACTCACGGGTCTTGGAGAAAGAAGTGTCCCGTAGCCCTACCACCAGCA
GTATTACCAGTGGCTACTTTTCCCACAGTGCCTCCAATGCCACCCTGTCTGACATGGTGGTCCCTTCTAGTGACAGCTCAGACCAGCTGG
CCATTCAGACGAAGGATGCAGACTCCACCGAGCACTCCACACCATCGCTTGTGCATGATTTCAGGCCGTCCTCAAACAAAGAGTTGACAG
AAGTCGAAAAAGGCTTGGTAAAGGACAAGATAATTGTGGTGCCACTCAAGGAAAACAGTGCCTTAGCCAAAGGGAGCCCATCATCCCAGA
GCATCCCTGAGAAAAACTCCAAATCACTGTGCAGGACTGGCTCATGTTCAGAACTAGATGCCTGCCCCAGCAAAATTAGCCAGCCAGCCA
GGGGATTCTGCCCCAGGGAGGTGACGGTAGAACACACCACCAACATCCTTGAAGACCATTCTTTCACAGAATTTATGGGAGTGTCAGAGG
GAAAAGATTTTGATGGTTTGACAGATTCTTCTGCTGGAGAGCTTTCCAGTAGGAGGAGTCTACCAAATAAAACAGGCGGCAAGACTGTCT
CCGATGGGCTCCACCACCCCAGCCAGCTGCATTCCAAGTTAGAGAATGACCAGGTAATAATTCCAGAGGCAGCCTTTTGGGTTCTGTGCT
GTCAATGAGTATGTCTAACTGTATGTCAACCCCAGAGGCCCTTCACCGCAACAACTTGGTAGGAAAGATTCATCCAGTTGTTTGTGACAG
CAAAGATGAGCCCACAGAGAAGCAGGCTCACTTCCTGCACAGCTGTCTCTGTCGGAGAGCAAGTCTGTTTTGGGAACTAGAACGCAATTG
TGAAATTATAAGACCAGTGGATTTTTTTACCTGGCACATGGGTTGGTGTTGAATGAAGTGTTCAGATGGATAAGGATCAATCTCATATTC
ATTCCCTGGGATGTTTAGTTACCAGTTTTCCCAAAGTGTTCTGGTAGCATCTACCATATTTCATCAAATCTGTGATTCCTTTGATTATTA

>78302_78302_5_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000379933_KIF13A_chr6_17765177_ENST00000378816_length(amino acids)=346AA_BP=68
MHYPAPADHAHSPAQHRHWRSRPLMQHLRKVTELGQLPRSPHAGALWREALQVHCVWPVIYHQWEHAQDSEEEENELEAINRKLISSQPY
VPVEFADFSVYNASLENREWFSSKVDLSNSRVLEKEVSRSPTTSSITSGYFSHSASNATLSDMVVPSSDSSDQLAIQTKDADSTEHSTPS
LVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSPSSQSIPEKNSKSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNI

--------------------------------------------------------------
>78302_78302_6_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000379933_KIF13A_chr6_17765177_ENST00000378843_length(transcript)=2133nt_BP=881nt
CGGGATGGCAACTGCGGTCACCCTGCTAAAGTCGGGGCGGGGGCGGCGGTCCTCCCCCTCACCCCCCCCAGTCCGAGCGCCGCCGCCGCC
GCCGCCGCCGCCGCCGCGGCCGCTCAGTAACACGTCCCCAGGAGACTCGCAGGAGCAACACGTGATGTGTCTACTTATCAGGGTTGCTCC
GACTGTGTGTTCCAGGAGTGGTGGCTCTGAGGTGTGACCCTGCCCACGTTTGGGCCCAGCCAGGTTCAGCCCCCCAATAAGGAGGGCAGC
TTGATAACACAAAGAAAACAGTGTCAACGAGTACTACCAAGAGAAGAAGACAAGAGGTCAACACAGACTCATTTTCTACTCCGTGTGAAT
GATAGCTACAGCAGGGGAAAGTTTCATAGTCTATCAGTGGGTCAGAAAATGGAGTTTTATAGCAGAGGCTTCTTAGAAGCTTAAACCCCT
GTCCCAATGACGTCAAGTTCGCCCGCTGGCTTGGAAGGTTCAGACCTATCTTCCATCAACACCATGATGTCGGCGGTCATGAGTGTAGGG
AAGGTCACAGAGAATGGCGGGAGCCCCCAGGGGATCAAGTCCCCCTCGAAGCCTCCAGGACCAAATCGGATTGGCAGAAGGAACCAGGAA
ACGAAAGAGGAGAAGTCTTCCTATAACTGCCCCCTGTGTGAGAAGATTTGCACTACCCAGCACCAGCTGACCATGCACATTCGCCAGCAC
AACACAGACACTGGAGGAGCCGACCACTCATGCAGCATCTGCGGAAAGTCACTGAGCTCGGCCAGCTCCCTCGATCGCCACATGCTGGTG
CACTCTGGCGAGAGGCCTTACAAGTGCACTGTGTGTGGCCAGTCATTTACCACCAATGGGAACATGCACAGGACTCTGAGGAGGAAGAAA
ATGAGCTGGAAGCTATTAACAGGAAGCTAATAAGTTCACAGCCTTATGTACCTGTGGAGTTTGCTGACTTCAGTGTTTACAATGCCAGCT
TGGAGAACAGGGAATGGTTTTCCTCTAAAGTAGATCTGTCAAACTCACGGGTCTTGGAGAAAGAAGTGTCCCGTAGCCCTACCACCAGCA
GTATTACCAGTGGCTACTTTTCCCACAGTGCCTCCAATGCCACCCTGTCTGACATGGTGGTCCCTTCTAGTGACAGCTCAGACCAGCTGG
CCATTCAGACGAAGGATGCAGACTCCACCGAGCACTCCACACCATCGCTTGTGCATGATTTCAGGCCGTCCTCAAACAAAGAGTTGACAG
AAGTCGAAAAAGGCTTGGTAAAGGACAAGATAATTGTGGTGCCACTCAAGGAAAACAGTGCCTTAGCCAAAGGGAGCCCATCATCCCAGA
GCATCCCTGAGAAAAACTCCAAATCACTGTGCAGGACTGGCTCATGTTCAGAACTAGATGCCTGCCCCAGCAAAATTAGCCAGCCAGCCA
GGGGATTCTGCCCCAGGGAGGTGACGGTAGAACACACCACCAACATCCTTGAAGACCATTCTTTCACAGAATTTATGGGAGTGTCAGAGG
GAAAAGATTTTGATGGTTTGACAGATTCTTCTGCTGGAGAGCTTTCCAGTAGGAGGAGTCTACCAAATAAAACAGGCGGCAAGACTGTCT
CCGATGGGCTCCACCACCCCAGCCAGCTGCATTCCAAGTTAGAGAATGACCAGGTAATAATTCCAGAGGCAGCCTTTTGGGTTCTGTGCT
GTCAATGAGTATGTCTAACTGTATGTCAACCCCAGAGGCCCTTCACCGCAACAACTTGGTAGGAAAGATTCATCCAGTTGTTTGTGACAG
CAAAGATGAGCCCACAGAGAAGCAGGCTCACTTCCTGCACAGCTGTCTCTGTCGGAGAGCAAGTCTGTTTTGGGAACTAGAACGCAATTG
TGAAATTATAAGACCAGTGGATTTTTTTACCTGGCACATGGGTTGGTGTTGAATGAAGTGTTCAGATGGATAAGGATCAATCTCATATTC
ATTCCCTGGGATGTTTAGTTACCAGTTTTCCCAAAGTGTTCTGGTAGCATCTACCATATTTCATCAAATCTGTGATTCCTTTGATTATTA

>78302_78302_6_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000379933_KIF13A_chr6_17765177_ENST00000378843_length(amino acids)=346AA_BP=68
MHYPAPADHAHSPAQHRHWRSRPLMQHLRKVTELGQLPRSPHAGALWREALQVHCVWPVIYHQWEHAQDSEEEENELEAINRKLISSQPY
VPVEFADFSVYNASLENREWFSSKVDLSNSRVLEKEVSRSPTTSSITSGYFSHSASNATLSDMVVPSSDSSDQLAIQTKDADSTEHSTPS
LVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSPSSQSIPEKNSKSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNI

--------------------------------------------------------------
>78302_78302_7_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000379938_KIF13A_chr6_17765177_ENST00000378816_length(transcript)=2212nt_BP=962nt
GAAGCTGGGCGGGGGGCCGAGACGGGGGCCGGGACGACGGCTGGGGCGCCGGGGTCGCCAGCTCCTCGCCCACCTCCCTCCCTGTGGGAG
AAGAGGAGGAGGGGAAGTGACTGCGGAGTTGATGAACTTTGCACATCCAGAAACGCCATTTTGATTCCTTTTCCGGAACAAGTTTGCATC
TCTCCTCGGTCTCTCCCTGAAGCCCACCGGTCCCCAACGCATCATGCCAGGGAGCCAAGCGTCCTGCCCGGCCGTTGCTCCGACTGTGTG
TTCCAGGAGTGGTGGCTCTGAGGTGTGACCCTGCCCACGTTTGGGCCCAGCCAGGTTCAGCCCCCCAATAAGGAGGGCAGCTTGATAACA
CAAAGAAAACAGTGTCAACGAGTACTACCAAGAGAAGAAGACAAGAGGTCAACACAGACTCATTTTCTACTCCGTGTGAATGATAGCTAC
AGCAGGGGAAAGTTTCATAGTCTATCAGTGGGTCAGAAAATGGAGTTTTATAGCAGAGGCTTCTTAGAAGCTTAAACCCCTGTCCCAATG
ACGTCAAGTTCGCCCGCTGGCTTGGAAGGTTCAGACCTATCTTCCATCAACACCATGATGTCGGCGGTCATGAGTGTAGGGAAGGTCACA
GAGAATGGCGGGAGCCCCCAGGGGATCAAGTCCCCCTCGAAGCCTCCAGGACCAAATCGGATTGGCAGAAGGAACCAGGAAACGAAAGAG
GAGAAGTCTTCCTATAACTGCCCCCTGTGTGAGAAGATTTGCACTACCCAGCACCAGCTGACCATGCACATTCGCCAGCACAACACAGAC
ACTGGAGGAGCCGACCACTCATGCAGCATCTGCGGAAAGTCACTGAGCTCGGCCAGCTCCCTCGATCGCCACATGCTGGTGCACTCTGGC
GAGAGGCCTTACAAGTGCACTGTGTGTGGCCAGTCATTTACCACCAATGGGAACATGCACAGGACTCTGAGGAGGAAGAAAATGAGCTGG
AAGCTATTAACAGGAAGCTAATAAGTTCACAGCCTTATGTACCTGTGGAGTTTGCTGACTTCAGTGTTTACAATGCCAGCTTGGAGAACA
GGGAATGGTTTTCCTCTAAAGTAGATCTGTCAAACTCACGGGTCTTGGAGAAAGAAGTGTCCCGTAGCCCTACCACCAGCAGTATTACCA
GTGGCTACTTTTCCCACAGTGCCTCCAATGCCACCCTGTCTGACATGGTGGTCCCTTCTAGTGACAGCTCAGACCAGCTGGCCATTCAGA
CGAAGGATGCAGACTCCACCGAGCACTCCACACCATCGCTTGTGCATGATTTCAGGCCGTCCTCAAACAAAGAGTTGACAGAAGTCGAAA
AAGGCTTGGTAAAGGACAAGATAATTGTGGTGCCACTCAAGGAAAACAGTGCCTTAGCCAAAGGGAGCCCATCATCCCAGAGCATCCCTG
AGAAAAACTCCAAATCACTGTGCAGGACTGGCTCATGTTCAGAACTAGATGCCTGCCCCAGCAAAATTAGCCAGCCAGCCAGGGGATTCT
GCCCCAGGGAGGTGACGGTAGAACACACCACCAACATCCTTGAAGACCATTCTTTCACAGAATTTATGGGAGTGTCAGAGGGAAAAGATT
TTGATGGTTTGACAGATTCTTCTGCTGGAGAGCTTTCCAGTAGGAGGAGTCTACCAAATAAAACAGGCGGCAAGACTGTCTCCGATGGGC
TCCACCACCCCAGCCAGCTGCATTCCAAGTTAGAGAATGACCAGGTAATAATTCCAGAGGCAGCCTTTTGGGTTCTGTGCTGTCAATGAG
TATGTCTAACTGTATGTCAACCCCAGAGGCCCTTCACCGCAACAACTTGGTAGGAAAGATTCATCCAGTTGTTTGTGACAGCAAAGATGA
GCCCACAGAGAAGCAGGCTCACTTCCTGCACAGCTGTCTCTGTCGGAGAGCAAGTCTGTTTTGGGAACTAGAACGCAATTGTGAAATTAT
AAGACCAGTGGATTTTTTTACCTGGCACATGGGTTGGTGTTGAATGAAGTGTTCAGATGGATAAGGATCAATCTCATATTCATTCCCTGG
GATGTTTAGTTACCAGTTTTCCCAAAGTGTTCTGGTAGCATCTACCATATTTCATCAAATCTGTGATTCCTTTGATTATTATATGAACCA

>78302_78302_7_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000379938_KIF13A_chr6_17765177_ENST00000378816_length(amino acids)=346AA_BP=68
MHYPAPADHAHSPAQHRHWRSRPLMQHLRKVTELGQLPRSPHAGALWREALQVHCVWPVIYHQWEHAQDSEEEENELEAINRKLISSQPY
VPVEFADFSVYNASLENREWFSSKVDLSNSRVLEKEVSRSPTTSSITSGYFSHSASNATLSDMVVPSSDSSDQLAIQTKDADSTEHSTPS
LVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSPSSQSIPEKNSKSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNI

--------------------------------------------------------------
>78302_78302_8_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000379938_KIF13A_chr6_17765177_ENST00000378843_length(transcript)=2214nt_BP=962nt
GAAGCTGGGCGGGGGGCCGAGACGGGGGCCGGGACGACGGCTGGGGCGCCGGGGTCGCCAGCTCCTCGCCCACCTCCCTCCCTGTGGGAG
AAGAGGAGGAGGGGAAGTGACTGCGGAGTTGATGAACTTTGCACATCCAGAAACGCCATTTTGATTCCTTTTCCGGAACAAGTTTGCATC
TCTCCTCGGTCTCTCCCTGAAGCCCACCGGTCCCCAACGCATCATGCCAGGGAGCCAAGCGTCCTGCCCGGCCGTTGCTCCGACTGTGTG
TTCCAGGAGTGGTGGCTCTGAGGTGTGACCCTGCCCACGTTTGGGCCCAGCCAGGTTCAGCCCCCCAATAAGGAGGGCAGCTTGATAACA
CAAAGAAAACAGTGTCAACGAGTACTACCAAGAGAAGAAGACAAGAGGTCAACACAGACTCATTTTCTACTCCGTGTGAATGATAGCTAC
AGCAGGGGAAAGTTTCATAGTCTATCAGTGGGTCAGAAAATGGAGTTTTATAGCAGAGGCTTCTTAGAAGCTTAAACCCCTGTCCCAATG
ACGTCAAGTTCGCCCGCTGGCTTGGAAGGTTCAGACCTATCTTCCATCAACACCATGATGTCGGCGGTCATGAGTGTAGGGAAGGTCACA
GAGAATGGCGGGAGCCCCCAGGGGATCAAGTCCCCCTCGAAGCCTCCAGGACCAAATCGGATTGGCAGAAGGAACCAGGAAACGAAAGAG
GAGAAGTCTTCCTATAACTGCCCCCTGTGTGAGAAGATTTGCACTACCCAGCACCAGCTGACCATGCACATTCGCCAGCACAACACAGAC
ACTGGAGGAGCCGACCACTCATGCAGCATCTGCGGAAAGTCACTGAGCTCGGCCAGCTCCCTCGATCGCCACATGCTGGTGCACTCTGGC
GAGAGGCCTTACAAGTGCACTGTGTGTGGCCAGTCATTTACCACCAATGGGAACATGCACAGGACTCTGAGGAGGAAGAAAATGAGCTGG
AAGCTATTAACAGGAAGCTAATAAGTTCACAGCCTTATGTACCTGTGGAGTTTGCTGACTTCAGTGTTTACAATGCCAGCTTGGAGAACA
GGGAATGGTTTTCCTCTAAAGTAGATCTGTCAAACTCACGGGTCTTGGAGAAAGAAGTGTCCCGTAGCCCTACCACCAGCAGTATTACCA
GTGGCTACTTTTCCCACAGTGCCTCCAATGCCACCCTGTCTGACATGGTGGTCCCTTCTAGTGACAGCTCAGACCAGCTGGCCATTCAGA
CGAAGGATGCAGACTCCACCGAGCACTCCACACCATCGCTTGTGCATGATTTCAGGCCGTCCTCAAACAAAGAGTTGACAGAAGTCGAAA
AAGGCTTGGTAAAGGACAAGATAATTGTGGTGCCACTCAAGGAAAACAGTGCCTTAGCCAAAGGGAGCCCATCATCCCAGAGCATCCCTG
AGAAAAACTCCAAATCACTGTGCAGGACTGGCTCATGTTCAGAACTAGATGCCTGCCCCAGCAAAATTAGCCAGCCAGCCAGGGGATTCT
GCCCCAGGGAGGTGACGGTAGAACACACCACCAACATCCTTGAAGACCATTCTTTCACAGAATTTATGGGAGTGTCAGAGGGAAAAGATT
TTGATGGTTTGACAGATTCTTCTGCTGGAGAGCTTTCCAGTAGGAGGAGTCTACCAAATAAAACAGGCGGCAAGACTGTCTCCGATGGGC
TCCACCACCCCAGCCAGCTGCATTCCAAGTTAGAGAATGACCAGGTAATAATTCCAGAGGCAGCCTTTTGGGTTCTGTGCTGTCAATGAG
TATGTCTAACTGTATGTCAACCCCAGAGGCCCTTCACCGCAACAACTTGGTAGGAAAGATTCATCCAGTTGTTTGTGACAGCAAAGATGA
GCCCACAGAGAAGCAGGCTCACTTCCTGCACAGCTGTCTCTGTCGGAGAGCAAGTCTGTTTTGGGAACTAGAACGCAATTGTGAAATTAT
AAGACCAGTGGATTTTTTTACCTGGCACATGGGTTGGTGTTGAATGAAGTGTTCAGATGGATAAGGATCAATCTCATATTCATTCCCTGG
GATGTTTAGTTACCAGTTTTCCCAAAGTGTTCTGGTAGCATCTACCATATTTCATCAAATCTGTGATTCCTTTGATTATTATATGAACCA

>78302_78302_8_RREB1-KIF13A_RREB1_chr6_7189555_ENST00000379938_KIF13A_chr6_17765177_ENST00000378843_length(amino acids)=346AA_BP=68
MHYPAPADHAHSPAQHRHWRSRPLMQHLRKVTELGQLPRSPHAGALWREALQVHCVWPVIYHQWEHAQDSEEEENELEAINRKLISSQPY
VPVEFADFSVYNASLENREWFSSKVDLSNSRVLEKEVSRSPTTSSITSGYFSHSASNATLSDMVVPSSDSSDQLAIQTKDADSTEHSTPS
LVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSPSSQSIPEKNSKSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RREB1-KIF13A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RREB1-KIF13A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RREB1-KIF13A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource