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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RSF1-PAK1 (FusionGDB2 ID:78407)

Fusion Gene Summary for RSF1-PAK1

check button Fusion gene summary
Fusion gene informationFusion gene name: RSF1-PAK1
Fusion gene ID: 78407
HgeneTgene
Gene symbol

RSF1

PAK1

Gene ID

51773

5585

Gene nameremodeling and spacing factor 1protein kinase N1
SynonymsHBXAP|RSF-1|XAP8|p325DBK|PAK-1|PAK1|PKN|PKN-ALPHA|PRK1|PRKCL1
Cytomap

11q14.1

19p13.12

Type of geneprotein-codingprotein-coding
Descriptionremodeling and spacing factor 1HBV pX-associated protein 8hepatitis B virus x-associated proteinp325 subunit of RSF chromatin-remodeling complexserine/threonine-protein kinase N1protease-activated kinase 1protein kinase C-like 1protein kinase C-like PKNprotein kinase C-related kinase 1protein kinase PKN-alphaserine-threonine kinase Nserine/threonine protein kinase N
Modification date2020031320200329
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000308488, ENST00000360355, 
ENST00000530604, ENST00000480887, 
ENST00000278568, ENST00000356341, 
ENST00000530617, ENST00000525542, 
ENST00000528203, 
Fusion gene scores* DoF score24 X 20 X 11=528022 X 17 X 10=3740
# samples 3226
** MAII scorelog2(32/5280*10)=-4.04439411935845
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(26/3740*10)=-3.84645474174655
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RSF1 [Title/Abstract] AND PAK1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRSF1(77531573)-PAK1(77103586), # samples:2
Anticipated loss of major functional domain due to fusion event.RSF1-PAK1 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
RSF1-PAK1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
RSF1-PAK1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
RSF1-PAK1 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRSF1

GO:0006334

nucleosome assembly

12972596

HgeneRSF1

GO:0006338

chromatin remodeling

9836642

HgeneRSF1

GO:0006352

DNA-templated transcription, initiation

9836642

HgeneRSF1

GO:0016584

nucleosome positioning

9836642

HgeneRSF1

GO:0043392

negative regulation of DNA binding

12972596

HgeneRSF1

GO:0045892

negative regulation of transcription, DNA-templated

11944984

HgeneRSF1

GO:0045893

positive regulation of transcription, DNA-templated

11788598

HgeneRSF1

GO:0050434

positive regulation of viral transcription

11788598

TgenePAK1

GO:0006357

regulation of transcription by RNA polymerase II

12514133

TgenePAK1

GO:0006468

protein phosphorylation

17332740

TgenePAK1

GO:0035407

histone H3-T11 phosphorylation

18066052


check buttonFusion gene breakpoints across RSF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PAK1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A4OTRSF1chr11

77531573

-PAK1chr11

77103586

-
ChimerDB4ESCATCGA-L5-A4OTRSF1chr11

77531574

-PAK1chr11

77103586

-
ChimerDB4OVTCGA-13-0899-01ARSF1chr11

77451776

-PAK1chr11

77070062

-
ChimerDB4OVTCGA-13-0899RSF1chr11

77475642

-PAK1chr11

77070062

-


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Fusion Gene ORF analysis for RSF1-PAK1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000308488ENST00000278568RSF1chr11

77531573

-PAK1chr11

77103586

-
5CDS-5UTRENST00000308488ENST00000278568RSF1chr11

77531574

-PAK1chr11

77103586

-
5CDS-5UTRENST00000308488ENST00000356341RSF1chr11

77531573

-PAK1chr11

77103586

-
5CDS-5UTRENST00000308488ENST00000356341RSF1chr11

77531574

-PAK1chr11

77103586

-
5CDS-5UTRENST00000308488ENST00000530617RSF1chr11

77531573

-PAK1chr11

77103586

-
5CDS-5UTRENST00000308488ENST00000530617RSF1chr11

77531574

-PAK1chr11

77103586

-
5CDS-5UTRENST00000360355ENST00000278568RSF1chr11

77531573

-PAK1chr11

77103586

-
5CDS-5UTRENST00000360355ENST00000278568RSF1chr11

77531574

-PAK1chr11

77103586

-
5CDS-5UTRENST00000360355ENST00000356341RSF1chr11

77531573

-PAK1chr11

77103586

-
5CDS-5UTRENST00000360355ENST00000356341RSF1chr11

77531574

-PAK1chr11

77103586

-
5CDS-5UTRENST00000360355ENST00000530617RSF1chr11

77531573

-PAK1chr11

77103586

-
5CDS-5UTRENST00000360355ENST00000530617RSF1chr11

77531574

-PAK1chr11

77103586

-
5CDS-intronENST00000308488ENST00000525542RSF1chr11

77531573

-PAK1chr11

77103586

-
5CDS-intronENST00000308488ENST00000525542RSF1chr11

77531574

-PAK1chr11

77103586

-
5CDS-intronENST00000308488ENST00000525542RSF1chr11

77451776

-PAK1chr11

77070062

-
5CDS-intronENST00000308488ENST00000525542RSF1chr11

77475642

-PAK1chr11

77070062

-
5CDS-intronENST00000308488ENST00000528203RSF1chr11

77531573

-PAK1chr11

77103586

-
5CDS-intronENST00000308488ENST00000528203RSF1chr11

77531574

-PAK1chr11

77103586

-
5CDS-intronENST00000360355ENST00000525542RSF1chr11

77531573

-PAK1chr11

77103586

-
5CDS-intronENST00000360355ENST00000525542RSF1chr11

77531574

-PAK1chr11

77103586

-
5CDS-intronENST00000360355ENST00000525542RSF1chr11

77451776

-PAK1chr11

77070062

-
5CDS-intronENST00000360355ENST00000525542RSF1chr11

77475642

-PAK1chr11

77070062

-
5CDS-intronENST00000360355ENST00000528203RSF1chr11

77531573

-PAK1chr11

77103586

-
5CDS-intronENST00000360355ENST00000528203RSF1chr11

77531574

-PAK1chr11

77103586

-
5UTR-5UTRENST00000530604ENST00000278568RSF1chr11

77531573

-PAK1chr11

77103586

-
5UTR-5UTRENST00000530604ENST00000278568RSF1chr11

77531574

-PAK1chr11

77103586

-
5UTR-5UTRENST00000530604ENST00000356341RSF1chr11

77531573

-PAK1chr11

77103586

-
5UTR-5UTRENST00000530604ENST00000356341RSF1chr11

77531574

-PAK1chr11

77103586

-
5UTR-5UTRENST00000530604ENST00000530617RSF1chr11

77531573

-PAK1chr11

77103586

-
5UTR-5UTRENST00000530604ENST00000530617RSF1chr11

77531574

-PAK1chr11

77103586

-
5UTR-intronENST00000530604ENST00000525542RSF1chr11

77531573

-PAK1chr11

77103586

-
5UTR-intronENST00000530604ENST00000525542RSF1chr11

77531574

-PAK1chr11

77103586

-
5UTR-intronENST00000530604ENST00000528203RSF1chr11

77531573

-PAK1chr11

77103586

-
5UTR-intronENST00000530604ENST00000528203RSF1chr11

77531574

-PAK1chr11

77103586

-
Frame-shiftENST00000308488ENST00000278568RSF1chr11

77451776

-PAK1chr11

77070062

-
Frame-shiftENST00000308488ENST00000356341RSF1chr11

77451776

-PAK1chr11

77070062

-
Frame-shiftENST00000308488ENST00000528203RSF1chr11

77451776

-PAK1chr11

77070062

-
Frame-shiftENST00000308488ENST00000530617RSF1chr11

77451776

-PAK1chr11

77070062

-
Frame-shiftENST00000360355ENST00000278568RSF1chr11

77451776

-PAK1chr11

77070062

-
Frame-shiftENST00000360355ENST00000356341RSF1chr11

77451776

-PAK1chr11

77070062

-
Frame-shiftENST00000360355ENST00000528203RSF1chr11

77451776

-PAK1chr11

77070062

-
Frame-shiftENST00000360355ENST00000530617RSF1chr11

77451776

-PAK1chr11

77070062

-
In-frameENST00000308488ENST00000278568RSF1chr11

77475642

-PAK1chr11

77070062

-
In-frameENST00000308488ENST00000356341RSF1chr11

77475642

-PAK1chr11

77070062

-
In-frameENST00000308488ENST00000528203RSF1chr11

77475642

-PAK1chr11

77070062

-
In-frameENST00000308488ENST00000530617RSF1chr11

77475642

-PAK1chr11

77070062

-
In-frameENST00000360355ENST00000278568RSF1chr11

77475642

-PAK1chr11

77070062

-
In-frameENST00000360355ENST00000356341RSF1chr11

77475642

-PAK1chr11

77070062

-
In-frameENST00000360355ENST00000528203RSF1chr11

77475642

-PAK1chr11

77070062

-
In-frameENST00000360355ENST00000530617RSF1chr11

77475642

-PAK1chr11

77070062

-
intron-3CDSENST00000480887ENST00000278568RSF1chr11

77451776

-PAK1chr11

77070062

-
intron-3CDSENST00000480887ENST00000278568RSF1chr11

77475642

-PAK1chr11

77070062

-
intron-3CDSENST00000480887ENST00000356341RSF1chr11

77451776

-PAK1chr11

77070062

-
intron-3CDSENST00000480887ENST00000356341RSF1chr11

77475642

-PAK1chr11

77070062

-
intron-3CDSENST00000480887ENST00000528203RSF1chr11

77451776

-PAK1chr11

77070062

-
intron-3CDSENST00000480887ENST00000528203RSF1chr11

77475642

-PAK1chr11

77070062

-
intron-3CDSENST00000480887ENST00000530617RSF1chr11

77451776

-PAK1chr11

77070062

-
intron-3CDSENST00000480887ENST00000530617RSF1chr11

77475642

-PAK1chr11

77070062

-
intron-3CDSENST00000530604ENST00000278568RSF1chr11

77451776

-PAK1chr11

77070062

-
intron-3CDSENST00000530604ENST00000278568RSF1chr11

77475642

-PAK1chr11

77070062

-
intron-3CDSENST00000530604ENST00000356341RSF1chr11

77451776

-PAK1chr11

77070062

-
intron-3CDSENST00000530604ENST00000356341RSF1chr11

77475642

-PAK1chr11

77070062

-
intron-3CDSENST00000530604ENST00000528203RSF1chr11

77451776

-PAK1chr11

77070062

-
intron-3CDSENST00000530604ENST00000528203RSF1chr11

77475642

-PAK1chr11

77070062

-
intron-3CDSENST00000530604ENST00000530617RSF1chr11

77451776

-PAK1chr11

77070062

-
intron-3CDSENST00000530604ENST00000530617RSF1chr11

77475642

-PAK1chr11

77070062

-
intron-5UTRENST00000480887ENST00000278568RSF1chr11

77531573

-PAK1chr11

77103586

-
intron-5UTRENST00000480887ENST00000278568RSF1chr11

77531574

-PAK1chr11

77103586

-
intron-5UTRENST00000480887ENST00000356341RSF1chr11

77531573

-PAK1chr11

77103586

-
intron-5UTRENST00000480887ENST00000356341RSF1chr11

77531574

-PAK1chr11

77103586

-
intron-5UTRENST00000480887ENST00000530617RSF1chr11

77531573

-PAK1chr11

77103586

-
intron-5UTRENST00000480887ENST00000530617RSF1chr11

77531574

-PAK1chr11

77103586

-
intron-intronENST00000480887ENST00000525542RSF1chr11

77531573

-PAK1chr11

77103586

-
intron-intronENST00000480887ENST00000525542RSF1chr11

77531574

-PAK1chr11

77103586

-
intron-intronENST00000480887ENST00000525542RSF1chr11

77451776

-PAK1chr11

77070062

-
intron-intronENST00000480887ENST00000525542RSF1chr11

77475642

-PAK1chr11

77070062

-
intron-intronENST00000480887ENST00000528203RSF1chr11

77531573

-PAK1chr11

77103586

-
intron-intronENST00000480887ENST00000528203RSF1chr11

77531574

-PAK1chr11

77103586

-
intron-intronENST00000530604ENST00000525542RSF1chr11

77451776

-PAK1chr11

77070062

-
intron-intronENST00000530604ENST00000525542RSF1chr11

77475642

-PAK1chr11

77070062

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000308488RSF1chr1177475642-ENST00000356341PAK1chr1177070062-33105823031742479
ENST00000308488RSF1chr1177475642-ENST00000530617PAK1chr1177070062-27945823031673456
ENST00000308488RSF1chr1177475642-ENST00000278568PAK1chr1177070062-21185823031766487
ENST00000308488RSF1chr1177475642-ENST00000528203PAK1chr1177070062-20425823031766487
ENST00000360355RSF1chr1177475642-ENST00000356341PAK1chr1177070062-31273991201559479
ENST00000360355RSF1chr1177475642-ENST00000530617PAK1chr1177070062-26113991201490456
ENST00000360355RSF1chr1177475642-ENST00000278568PAK1chr1177070062-19353991201583487
ENST00000360355RSF1chr1177475642-ENST00000528203PAK1chr1177070062-18593991201583487

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000308488ENST00000356341RSF1chr1177475642-PAK1chr1177070062-0.0013528890.99864715
ENST00000308488ENST00000530617RSF1chr1177475642-PAK1chr1177070062-0.0012806590.99871933
ENST00000308488ENST00000278568RSF1chr1177475642-PAK1chr1177070062-0.0022524540.9977475
ENST00000308488ENST00000528203RSF1chr1177475642-PAK1chr1177070062-0.0029340450.99706596
ENST00000360355ENST00000356341RSF1chr1177475642-PAK1chr1177070062-0.0013456740.99865425
ENST00000360355ENST00000530617RSF1chr1177475642-PAK1chr1177070062-0.0012772520.99872273
ENST00000360355ENST00000278568RSF1chr1177475642-PAK1chr1177070062-0.0023834970.9976165
ENST00000360355ENST00000528203RSF1chr1177475642-PAK1chr1177070062-0.0031887680.9968112

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Fusion Genomic Features for RSF1-PAK1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RSF1-PAK1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:77531573/chr11:77103586)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRSF1chr11:77475642chr11:77070062ENST00000308488-21617_84931442.0DomainNote=DDT
HgeneRSF1chr11:77475642chr11:77070062ENST00000360355-21517_84931411.0DomainNote=DDT
TgenePAK1chr11:77475642chr11:77070062ENST00000278568416270_521159554.0DomainProtein kinase
TgenePAK1chr11:77475642chr11:77070062ENST00000356341415270_521159546.0DomainProtein kinase
TgenePAK1chr11:77475642chr11:77070062ENST00000278568416276_284159554.0Nucleotide bindingNote=ATP
TgenePAK1chr11:77475642chr11:77070062ENST00000278568416345_347159554.0Nucleotide bindingNote=ATP
TgenePAK1chr11:77475642chr11:77070062ENST00000356341415276_284159546.0Nucleotide bindingNote=ATP
TgenePAK1chr11:77475642chr11:77070062ENST00000356341415345_347159546.0Nucleotide bindingNote=ATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRSF1chr11:77475642chr11:77070062ENST00000308488-216942_1012931442.0Coiled coilOntology_term=ECO:0000255
HgeneRSF1chr11:77475642chr11:77070062ENST00000360355-215942_1012931411.0Coiled coilOntology_term=ECO:0000255
HgeneRSF1chr11:77475642chr11:77070062ENST00000480887-111942_101201190.0Coiled coilOntology_term=ECO:0000255
HgeneRSF1chr11:77475642chr11:77070062ENST00000308488-2161080_1083931442.0Compositional biasNote=Poly-Ala
HgeneRSF1chr11:77475642chr11:77070062ENST00000308488-2161146_1243931442.0Compositional biasNote=Arg-rich
HgeneRSF1chr11:77475642chr11:77070062ENST00000308488-2161286_1292931442.0Compositional biasNote=Poly-Glu
HgeneRSF1chr11:77475642chr11:77070062ENST00000308488-2161419_1424931442.0Compositional biasNote=Poly-Glu
HgeneRSF1chr11:77475642chr11:77070062ENST00000308488-216226_372931442.0Compositional biasNote=Glu-rich
HgeneRSF1chr11:77475642chr11:77070062ENST00000308488-216875_884931442.0Compositional biasNote=Poly-Glu
HgeneRSF1chr11:77475642chr11:77070062ENST00000360355-2151080_1083931411.0Compositional biasNote=Poly-Ala
HgeneRSF1chr11:77475642chr11:77070062ENST00000360355-2151146_1243931411.0Compositional biasNote=Arg-rich
HgeneRSF1chr11:77475642chr11:77070062ENST00000360355-2151286_1292931411.0Compositional biasNote=Poly-Glu
HgeneRSF1chr11:77475642chr11:77070062ENST00000360355-2151419_1424931411.0Compositional biasNote=Poly-Glu
HgeneRSF1chr11:77475642chr11:77070062ENST00000360355-215226_372931411.0Compositional biasNote=Glu-rich
HgeneRSF1chr11:77475642chr11:77070062ENST00000360355-215875_884931411.0Compositional biasNote=Poly-Glu
HgeneRSF1chr11:77475642chr11:77070062ENST00000480887-1111080_108301190.0Compositional biasNote=Poly-Ala
HgeneRSF1chr11:77475642chr11:77070062ENST00000480887-1111146_124301190.0Compositional biasNote=Arg-rich
HgeneRSF1chr11:77475642chr11:77070062ENST00000480887-1111286_129201190.0Compositional biasNote=Poly-Glu
HgeneRSF1chr11:77475642chr11:77070062ENST00000480887-1111419_142401190.0Compositional biasNote=Poly-Glu
HgeneRSF1chr11:77475642chr11:77070062ENST00000480887-111226_37201190.0Compositional biasNote=Glu-rich
HgeneRSF1chr11:77475642chr11:77070062ENST00000480887-111875_88401190.0Compositional biasNote=Poly-Glu
HgeneRSF1chr11:77475642chr11:77070062ENST00000480887-11117_8401190.0DomainNote=DDT
HgeneRSF1chr11:77475642chr11:77070062ENST00000308488-216891_941931442.0Zinc fingerPHD-type
HgeneRSF1chr11:77475642chr11:77070062ENST00000360355-215891_941931411.0Zinc fingerPHD-type
HgeneRSF1chr11:77475642chr11:77070062ENST00000480887-111891_94101190.0Zinc fingerPHD-type
TgenePAK1chr11:77475642chr11:77070062ENST0000027856841675_88159554.0DomainCRIB
TgenePAK1chr11:77475642chr11:77070062ENST0000035634141575_88159546.0DomainCRIB
TgenePAK1chr11:77475642chr11:77070062ENST0000027856841670_140159554.0RegionNote=Autoregulatory region
TgenePAK1chr11:77475642chr11:77070062ENST0000027856841675_105159554.0RegionNote=GTPase-binding
TgenePAK1chr11:77475642chr11:77070062ENST0000035634141570_140159546.0RegionNote=Autoregulatory region
TgenePAK1chr11:77475642chr11:77070062ENST0000035634141575_105159546.0RegionNote=GTPase-binding


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Fusion Gene Sequence for RSF1-PAK1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>78407_78407_1_RSF1-PAK1_RSF1_chr11_77475642_ENST00000308488_PAK1_chr11_77070062_ENST00000278568_length(transcript)=2118nt_BP=582nt
TTGTTTTCATTCCCCCTGTCACACGAGGCAGTGGCAAGCCCGAAGGGGAGGAGAGAAGGGGGCGGAAAGAGGGCGGAAAGTGAAAGGCGC
CGAGGGCCGCTCTGTCTCCCGTCTGACTCGGTTCTCGACTGCTCCGGGCCGCCGATGTATTGTGGGATCGCGGAGCCGTCCCTGAGACGC
TGGGATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCC
CCCATCGCCTCCTCCTCCATCCTCCAGTTCAAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCG
TGCCCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGG
GTGCTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGC
AAATCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGAATGTGAAGGCTGTGTCTGAGACTCCTGCAGTGCCACCAGTTTCAGAA
GATGAGGATGATGATGATGATGATGCTACCCCACCACCAGTGATTGCTCCACGCCCAGAGCACACAAAATCTGTATACACACGGTCTGTG
ATTGAACCACTTCCTGTCACTCCAACTCGGGACGTGGCTACATCTCCCATTTCACCTACTGAAAATAACACCACTCCACCAGATGCTTTG
ACCCGGAATACTGAGAAGCAGAAGAAGAAGCCTAAAATGTCTGATGAGGAGATCTTGGAGAAATTACGAAGCATAGTGAGTGTGGGCGAT
CCTAAGAAGAAATATACACGGTTTGAGAAGATTGGACAAGGTGCTTCAGGCACCGTGTACACAGCAATGGATGTGGCCACAGGACAGGAG
GTGGCCATTAAGCAGATGAATCTTCAGCAGCAGCCCAAGAAAGAGCTGATTATTAATGAGATCCTGGTCATGAGGGAAAACAAGAACCCA
AACATTGTGAATTACTTGGACAGTTACCTCGTGGGAGATGAGCTGTGGGTTGTTATGGAATACTTGGCTGGAGGCTCCTTGACAGATGTG
GTGACAGAAACTTGCATGGATGAAGGCCAAATTGCAGCTGTGTGCCGTGAGTGTCTGCAGGCTCTGGAGTTCTTGCATTCGAACCAGGTC
ATTCACAGAGACATCAAGAGTGACAATATTCTGTTGGGAATGGATGGCTCTGTCAAGCTAACTGACTTTGGATTCTGTGCACAGATAACC
CCAGAGCAGAGCAAACGGAGCACCATGGTAGGAACCCCATACTGGATGGCACCAGAGGTTGTGACACGAAAGGCCTATGGGCCCAAGGTT
GACATCTGGTCCCTGGGCATCATGGCCATCGAAATGATTGAAGGGGAGCCTCCATACCTCAATGAAAACCCTCTGAGAGCCTTGTACCTC
ATTGCCACCAATGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGAT
GTGGAGAAGAGAGGTTCAGCTAAAGAGCTGCTACAGGTGAGAAAACTGAGGTTTCAAGTGTTTAGTAACTTTTCCATGATAGCTGCATCA
ATTCCTGAAGATTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAAGGAGGCAACAAAGAACAATCACTAAAACCACAC
TCACCCCAGCCTCATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAGAAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGC
TTCTCCCATTTCCTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTA
ATCAGATGATGGCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGGTTTATGATTAAGGGTTTATATAAATAAATG

>78407_78407_1_RSF1-PAK1_RSF1_chr11_77475642_ENST00000308488_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=487AA_BP=0
MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKY
LIKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKP
KMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLV
GDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVG
TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELL

--------------------------------------------------------------
>78407_78407_2_RSF1-PAK1_RSF1_chr11_77475642_ENST00000308488_PAK1_chr11_77070062_ENST00000356341_length(transcript)=3310nt_BP=582nt
TTGTTTTCATTCCCCCTGTCACACGAGGCAGTGGCAAGCCCGAAGGGGAGGAGAGAAGGGGGCGGAAAGAGGGCGGAAAGTGAAAGGCGC
CGAGGGCCGCTCTGTCTCCCGTCTGACTCGGTTCTCGACTGCTCCGGGCCGCCGATGTATTGTGGGATCGCGGAGCCGTCCCTGAGACGC
TGGGATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCC
CCCATCGCCTCCTCCTCCATCCTCCAGTTCAAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCG
TGCCCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGG
GTGCTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGC
AAATCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGAATGTGAAGGCTGTGTCTGAGACTCCTGCAGTGCCACCAGTTTCAGAA
GATGAGGATGATGATGATGATGATGCTACCCCACCACCAGTGATTGCTCCACGCCCAGAGCACACAAAATCTGTATACACACGGTCTGTG
ATTGAACCACTTCCTGTCACTCCAACTCGGGACGTGGCTACATCTCCCATTTCACCTACTGAAAATAACACCACTCCACCAGATGCTTTG
ACCCGGAATACTGAGAAGCAGAAGAAGAAGCCTAAAATGTCTGATGAGGAGATCTTGGAGAAATTACGAAGCATAGTGAGTGTGGGCGAT
CCTAAGAAGAAATATACACGGTTTGAGAAGATTGGACAAGGTGCTTCAGGCACCGTGTACACAGCAATGGATGTGGCCACAGGACAGGAG
GTGGCCATTAAGCAGATGAATCTTCAGCAGCAGCCCAAGAAAGAGCTGATTATTAATGAGATCCTGGTCATGAGGGAAAACAAGAACCCA
AACATTGTGAATTACTTGGACAGTTACCTCGTGGGAGATGAGCTGTGGGTTGTTATGGAATACTTGGCTGGAGGCTCCTTGACAGATGTG
GTGACAGAAACTTGCATGGATGAAGGCCAAATTGCAGCTGTGTGCCGTGAGTGTCTGCAGGCTCTGGAGTTCTTGCATTCGAACCAGGTC
ATTCACAGAGACATCAAGAGTGACAATATTCTGTTGGGAATGGATGGCTCTGTCAAGCTAACTGACTTTGGATTCTGTGCACAGATAACC
CCAGAGCAGAGCAAACGGAGCACCATGGTAGGAACCCCATACTGGATGGCACCAGAGGTTGTGACACGAAAGGCCTATGGGCCCAAGGTT
GACATCTGGTCCCTGGGCATCATGGCCATCGAAATGATTGAAGGGGAGCCTCCATACCTCAATGAAAACCCTCTGAGAGCCTTGTACCTC
ATTGCCACCAATGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGAT
GTGGAGAAGAGAGGTTCAGCTAAAGAGCTGCTACAGCATCAATTCCTGAAGATTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCT
GCAGCTAAGGAGGCAACAAAGAACAATCACTAAAACCACACTCACCCCAGCCTCATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTT
CAGAAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGCTTCTCCCATTTCCTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAA
CCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTAATCAGATGATGGCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGA
TATGAGGGTGGTTTATGATTAAGGGTTTATATAAATAAATGTTTCTAGTCTTCCGTGTGTCAAAATCCTCACCTCCTTCATAACCATCTC
CCACAATTAATTCTTGACTATATAAATTTATGGTTTGATAATATTATCAATTTGTAATCAATTGAGATTTCTTTAGTGCTTGCTTTTCTG
TGACTCAACTGCCCAGACACCTCATTGTACTTGAAAACTGGAACAGCTTGGGAATGCCATGGGGTTTGATAATCTGCCAGGGACATGAAG
AGGCTCAGCTTCCTGGACCATGACTTTGGCTCAGCTGATCCTGACATGGGAGAACAACCACATTTTTCTTTGTGTGTGCTTCTAGCAGCT
GTTCGGGAGGACCTTGACCCAATAGTGTTCCCATGCTGTTTCTTGTGAAATGCTCTCGGCTATGTAGCAGCTTTTGATTCCCTGCATACC
CTAGGCTGCTGCCCCTATCCTGTCCCTTGTTTATAACATTGAGAGGTTTTCTAGGGCACATACTGAGTGAGAGCAGTGTTGAGAAGTCGG
GGAAAATGGTGACTACTTTTAGAGCAAGGCTGGGCATCAGCACCTGTCCAGCTCTACTTGTGTGATGTTTCAGGAACTCAGCCCCTTTTT
CTGCCTAGGATAAGGAGCTGAAAGATTAACTTGGATCTTCTAATGGTCCAAATCTTTTGGTCACAATAAAGAGTCTCCAAATTAGAGACT
GCATGTTAGTTCTGGATGGATTTGGTGGCCTGACATGATACCCTGCCAGCTGTGAGGGGACCCCGTTTTTAAGATGCATGGCCAAGCTCT
CTGCAAATGGAAATGCTTACACTGGGTGTTGGGGATGTTTGCTACCTCCTGCTATTTTTGTGGTTTTGGTTCTCCCACTATGGTAGGACC
CCTGGCCAGCATTGTGGCTTGTCATGTCAGCCCCATTGACTACCTTCTCATGCTCTGAGGTACTACTGCCTCTGCAGCACAAATTTCTAT
TTCTGTCAATAAAAGGAGATGAAAATATTCTATTGGAGTATGCCTTTCTTTTTTCTCTTCGTTTTTTCTTTCCTTTTCTAATTTTTTATA
TGAAATAATGAGTAGTTTCTTCCTGAACCATTTGAGAGTGGTAAGTTGCAGATAGAATGCCCCTTTACCACTATATACCTGAATGTGTAT
TCTTTCTTTTTAACACTTTTATTTTAAATATAAATTAAGAGAAATGGGCCAAAACCATTTGTATTGTTTAAAGAATAATTATAAACACAC

>78407_78407_2_RSF1-PAK1_RSF1_chr11_77475642_ENST00000308488_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=479AA_BP=0
MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKY
LIKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKP
KMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLV
GDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVG
TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELL

--------------------------------------------------------------
>78407_78407_3_RSF1-PAK1_RSF1_chr11_77475642_ENST00000308488_PAK1_chr11_77070062_ENST00000528203_length(transcript)=2042nt_BP=582nt
TTGTTTTCATTCCCCCTGTCACACGAGGCAGTGGCAAGCCCGAAGGGGAGGAGAGAAGGGGGCGGAAAGAGGGCGGAAAGTGAAAGGCGC
CGAGGGCCGCTCTGTCTCCCGTCTGACTCGGTTCTCGACTGCTCCGGGCCGCCGATGTATTGTGGGATCGCGGAGCCGTCCCTGAGACGC
TGGGATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCC
CCCATCGCCTCCTCCTCCATCCTCCAGTTCAAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCG
TGCCCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGG
GTGCTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGC
AAATCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGAATGTGAAGGCTGTGTCTGAGACTCCTGCAGTGCCACCAGTTTCAGAA
GATGAGGATGATGATGATGATGATGCTACCCCACCACCAGTGATTGCTCCACGCCCAGAGCACACAAAATCTGTATACACACGGTCTGTG
ATTGAACCACTTCCTGTCACTCCAACTCGGGACGTGGCTACATCTCCCATTTCACCTACTGAAAATAACACCACTCCACCAGATGCTTTG
ACCCGGAATACTGAGAAGCAGAAGAAGAAGCCTAAAATGTCTGATGAGGAGATCTTGGAGAAATTACGAAGCATAGTGAGTGTGGGCGAT
CCTAAGAAGAAATATACACGGTTTGAGAAGATTGGACAAGGTGCTTCAGGCACCGTGTACACAGCAATGGATGTGGCCACAGGACAGGAG
GTGGCCATTAAGCAGATGAATCTTCAGCAGCAGCCCAAGAAAGAGCTGATTATTAATGAGATCCTGGTCATGAGGGAAAACAAGAACCCA
AACATTGTGAATTACTTGGACAGTTACCTCGTGGGAGATGAGCTGTGGGTTGTTATGGAATACTTGGCTGGAGGCTCCTTGACAGATGTG
GTGACAGAAACTTGCATGGATGAAGGCCAAATTGCAGCTGTGTGCCGTGAGTGTCTGCAGGCTCTGGAGTTCTTGCATTCGAACCAGGTC
ATTCACAGAGACATCAAGAGTGACAATATTCTGTTGGGAATGGATGGCTCTGTCAAGCTAACTGACTTTGGATTCTGTGCACAGATAACC
CCAGAGCAGAGCAAACGGAGCACCATGGTAGGAACCCCATACTGGATGGCACCAGAGGTTGTGACACGAAAGGCCTATGGGCCCAAGGTT
GACATCTGGTCCCTGGGCATCATGGCCATCGAAATGATTGAAGGGGAGCCTCCATACCTCAATGAAAACCCTCTGAGAGCCTTGTACCTC
ATTGCCACCAATGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGAT
GTGGAGAAGAGAGGTTCAGCTAAAGAGCTGCTACAGGTGAGAAAACTGAGGTTTCAAGTGTTTAGTAACTTTTCCATGATAGCTGCATCA
ATTCCTGAAGATTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAAGGAGGCAACAAAGAACAATCACTAAAACCACAC
TCACCCCAGCCTCATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAGAAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGC
TTCTCCCATTTCCTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTA

>78407_78407_3_RSF1-PAK1_RSF1_chr11_77475642_ENST00000308488_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=487AA_BP=0
MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKY
LIKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKP
KMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLV
GDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVG
TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELL

--------------------------------------------------------------
>78407_78407_4_RSF1-PAK1_RSF1_chr11_77475642_ENST00000308488_PAK1_chr11_77070062_ENST00000530617_length(transcript)=2794nt_BP=582nt
TTGTTTTCATTCCCCCTGTCACACGAGGCAGTGGCAAGCCCGAAGGGGAGGAGAGAAGGGGGCGGAAAGAGGGCGGAAAGTGAAAGGCGC
CGAGGGCCGCTCTGTCTCCCGTCTGACTCGGTTCTCGACTGCTCCGGGCCGCCGATGTATTGTGGGATCGCGGAGCCGTCCCTGAGACGC
TGGGATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCC
CCCATCGCCTCCTCCTCCATCCTCCAGTTCAAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCG
TGCCCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGG
GTGCTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGC
AAATCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGAATGTGAAGGCTGTGTCTGAGACTCCTGCAGTGCCACCAGTTTCAGAA
GATGAGGATGATGATGATGATGATGCTACCCCACCACCAGTGATTGCTCCACGCCCAGAGCACACAAAATCTGTATACACACGGTCTGTG
ATTGAACCACTTCCTGTCACTCCAACTCGGGACGTGGCTACATCTCCCATTTCACCTACTGAAAATAACACCACTCCACCAGATGCTTTG
ACCCGGAATACTGAGAAGCAGAAGAAGAAGCCTAAAATGTCTGATGAGGAGATCTTGGAGAAATTACGAAGCATAGTGAGTGTGGGCGAT
CCTAAGAAGAAATATACACGGTTTGAGAAGATTGGACAAGGTGCTTCAGGCACCGTGTACACAGCAATGGATGTGGCCACAGGACAGGAG
GTGGCCATTAAGCAGATGAATCTTCAGCAGCAGCCCAAGAAAGAGCTGATTATTAATGAGATCCTGGTCATGAGGGAAAACAAGAACCCA
AACATTGTGAATTACTTGGACAGTTACCTCGTGGGAGATGAGCTGTGGGTTGTTATGGAATACTTGGCTGGAGGCTCCTTGACAGATGTG
GTGACAGAAACTTGCATGGATGAAGGCCAAATTGCAGCTGTGTGCCGTGAGTGTCTGCAGGCTCTGGAGTTCTTGCATTCGAACCAGGTC
ATTCACAGAGACATCAAGAGTGACAATATTCTGTTGGGAATGGATGGCTCTGTCAAGCTAACTGACTTTGGATTCTGTGCACAGATAACC
CCAGAGCAGAGCAAACGGAGCACCATGGTAGGAACCCCATACTGGATGGCACCAGAGGTTGTGACACGAAAGGCCTATGGGCCCAAGGTT
GACATCTGGTCCCTGGGCATCATGGCCATCGAAATGATTGAAGGGGAGCCTCCATACCTCAATGAAAACCCTCTGAGAGCCTTGTACCTC
ATTGCCACCAATGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGAT
GTGGAGAAGAGAGGTTCAGCTAAAGAGCTGCTACAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACT
GCAACTGAATGACTAATCAGATGATGGCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGGTTTATGATTAAGGGT
TTATATAAATAAATGTTTCTAGTCTTCCGTGTGTCAAAATCCTCACCTCCTTCATAACCATCTCCCACAATTAATTCTTGACTATATAAA
TTTATGGTTTGATAATATTATCAATTTGTAATCAATTGAGATTTCTTTAGTGCTTGCTTTTCTGTGACTCAACTGCCCAGACACCTCATT
GTACTTGAAAACTGGAACAGCTTGGGAATGCCATGGGGTTTGATAATCTGCCAGGGACATGAAGAGGCTCAGCTTCCTGGACCATGACTT
TGGCTCAGCTGATCCTGACATGGGAGAACAACCACATTTTTCTTTGTGTGTGCTTCTAGCAGCTGTTCGGGAGGACCTTGACCCAATAGT
GTTCCCATGCTGTTTCTTGTGAAATGCTCTCGGCTATGTAGCAGCTTTTGATTCCCTGCATACCCTAGGCTGCTGCCCCTATCCTGTCCC
TTGTTTATAACATTGAGAGGTTTTCTAGGGCACATACTGAGTGAGAGCAGTGTTGAGAAGTCGGGGAAAATGGTGACTACTTTTAGAGCA
AGGCTGGGCATCAGCACCTGTCCAGCTCTACTTGTGTGATGTTTCAGGAACTCAGCCCCTTTTTCTGCCTAGGATAAGGAGCTGAAAGAT
TAACTTGGATCTTCTAATGGTCCAAATCTTTTGGTCACAATAAAGAGTCTCCAAATTAGAGACTGCATGTTAGTTCTGGATGGATTTGGT
GGCCTGACATGATACCCTGCCAGCTGTGAGGGGACCCCGTTTTTAAGATGCATGGCCAAGCTCTCTGCAAATGGAAATGCTTACACTGGG
TGTTGGGGATGTTTGCTACCTCCTGCTATTTTTGTGGTTTTGGTTCTCCCACTATGGTAGGACCCCTGGCCAGCATTGTGGCTTGTCATG
TCAGCCCCATTGACTACCTTCTCATGCTCTGAGGTACTACTGCCTCTGCAGCACAAATTTCTATTTCTGTCAATAAAAGGAGATGAAAAT

>78407_78407_4_RSF1-PAK1_RSF1_chr11_77475642_ENST00000308488_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=456AA_BP=0
MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKY
LIKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKP
KMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLV
GDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVG
TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELL

--------------------------------------------------------------
>78407_78407_5_RSF1-PAK1_RSF1_chr11_77475642_ENST00000360355_PAK1_chr11_77070062_ENST00000278568_length(transcript)=1935nt_BP=399nt
GATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCCCCC
ATCGCCTCCTCCTCCATCCTCCAGTTCAAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCGTGC
CCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGGGTG
CTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGCAAA
TCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGAATGTGAAGGCTGTGTCTGAGACTCCTGCAGTGCCACCAGTTTCAGAAGAT
GAGGATGATGATGATGATGATGCTACCCCACCACCAGTGATTGCTCCACGCCCAGAGCACACAAAATCTGTATACACACGGTCTGTGATT
GAACCACTTCCTGTCACTCCAACTCGGGACGTGGCTACATCTCCCATTTCACCTACTGAAAATAACACCACTCCACCAGATGCTTTGACC
CGGAATACTGAGAAGCAGAAGAAGAAGCCTAAAATGTCTGATGAGGAGATCTTGGAGAAATTACGAAGCATAGTGAGTGTGGGCGATCCT
AAGAAGAAATATACACGGTTTGAGAAGATTGGACAAGGTGCTTCAGGCACCGTGTACACAGCAATGGATGTGGCCACAGGACAGGAGGTG
GCCATTAAGCAGATGAATCTTCAGCAGCAGCCCAAGAAAGAGCTGATTATTAATGAGATCCTGGTCATGAGGGAAAACAAGAACCCAAAC
ATTGTGAATTACTTGGACAGTTACCTCGTGGGAGATGAGCTGTGGGTTGTTATGGAATACTTGGCTGGAGGCTCCTTGACAGATGTGGTG
ACAGAAACTTGCATGGATGAAGGCCAAATTGCAGCTGTGTGCCGTGAGTGTCTGCAGGCTCTGGAGTTCTTGCATTCGAACCAGGTCATT
CACAGAGACATCAAGAGTGACAATATTCTGTTGGGAATGGATGGCTCTGTCAAGCTAACTGACTTTGGATTCTGTGCACAGATAACCCCA
GAGCAGAGCAAACGGAGCACCATGGTAGGAACCCCATACTGGATGGCACCAGAGGTTGTGACACGAAAGGCCTATGGGCCCAAGGTTGAC
ATCTGGTCCCTGGGCATCATGGCCATCGAAATGATTGAAGGGGAGCCTCCATACCTCAATGAAAACCCTCTGAGAGCCTTGTACCTCATT
GCCACCAATGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTG
GAGAAGAGAGGTTCAGCTAAAGAGCTGCTACAGGTGAGAAAACTGAGGTTTCAAGTGTTTAGTAACTTTTCCATGATAGCTGCATCAATT
CCTGAAGATTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAAGGAGGCAACAAAGAACAATCACTAAAACCACACTCA
CCCCAGCCTCATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAGAAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGCTTC
TCCCATTTCCTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTAATC
AGATGATGGCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGGTTTATGATTAAGGGTTTATATAAATAAATGTTT

>78407_78407_5_RSF1-PAK1_RSF1_chr11_77475642_ENST00000360355_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=487AA_BP=0
MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKY
LIKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKP
KMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLV
GDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVG
TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELL

--------------------------------------------------------------
>78407_78407_6_RSF1-PAK1_RSF1_chr11_77475642_ENST00000360355_PAK1_chr11_77070062_ENST00000356341_length(transcript)=3127nt_BP=399nt
GATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCCCCC
ATCGCCTCCTCCTCCATCCTCCAGTTCAAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCGTGC
CCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGGGTG
CTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGCAAA
TCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGAATGTGAAGGCTGTGTCTGAGACTCCTGCAGTGCCACCAGTTTCAGAAGAT
GAGGATGATGATGATGATGATGCTACCCCACCACCAGTGATTGCTCCACGCCCAGAGCACACAAAATCTGTATACACACGGTCTGTGATT
GAACCACTTCCTGTCACTCCAACTCGGGACGTGGCTACATCTCCCATTTCACCTACTGAAAATAACACCACTCCACCAGATGCTTTGACC
CGGAATACTGAGAAGCAGAAGAAGAAGCCTAAAATGTCTGATGAGGAGATCTTGGAGAAATTACGAAGCATAGTGAGTGTGGGCGATCCT
AAGAAGAAATATACACGGTTTGAGAAGATTGGACAAGGTGCTTCAGGCACCGTGTACACAGCAATGGATGTGGCCACAGGACAGGAGGTG
GCCATTAAGCAGATGAATCTTCAGCAGCAGCCCAAGAAAGAGCTGATTATTAATGAGATCCTGGTCATGAGGGAAAACAAGAACCCAAAC
ATTGTGAATTACTTGGACAGTTACCTCGTGGGAGATGAGCTGTGGGTTGTTATGGAATACTTGGCTGGAGGCTCCTTGACAGATGTGGTG
ACAGAAACTTGCATGGATGAAGGCCAAATTGCAGCTGTGTGCCGTGAGTGTCTGCAGGCTCTGGAGTTCTTGCATTCGAACCAGGTCATT
CACAGAGACATCAAGAGTGACAATATTCTGTTGGGAATGGATGGCTCTGTCAAGCTAACTGACTTTGGATTCTGTGCACAGATAACCCCA
GAGCAGAGCAAACGGAGCACCATGGTAGGAACCCCATACTGGATGGCACCAGAGGTTGTGACACGAAAGGCCTATGGGCCCAAGGTTGAC
ATCTGGTCCCTGGGCATCATGGCCATCGAAATGATTGAAGGGGAGCCTCCATACCTCAATGAAAACCCTCTGAGAGCCTTGTACCTCATT
GCCACCAATGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTG
GAGAAGAGAGGTTCAGCTAAAGAGCTGCTACAGCATCAATTCCTGAAGATTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCA
GCTAAGGAGGCAACAAAGAACAATCACTAAAACCACACTCACCCCAGCCTCATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAG
AAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGCTTCTCCCATTTCCTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCG
TGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTAATCAGATGATGGCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATAT
GAGGGTGGTTTATGATTAAGGGTTTATATAAATAAATGTTTCTAGTCTTCCGTGTGTCAAAATCCTCACCTCCTTCATAACCATCTCCCA
CAATTAATTCTTGACTATATAAATTTATGGTTTGATAATATTATCAATTTGTAATCAATTGAGATTTCTTTAGTGCTTGCTTTTCTGTGA
CTCAACTGCCCAGACACCTCATTGTACTTGAAAACTGGAACAGCTTGGGAATGCCATGGGGTTTGATAATCTGCCAGGGACATGAAGAGG
CTCAGCTTCCTGGACCATGACTTTGGCTCAGCTGATCCTGACATGGGAGAACAACCACATTTTTCTTTGTGTGTGCTTCTAGCAGCTGTT
CGGGAGGACCTTGACCCAATAGTGTTCCCATGCTGTTTCTTGTGAAATGCTCTCGGCTATGTAGCAGCTTTTGATTCCCTGCATACCCTA
GGCTGCTGCCCCTATCCTGTCCCTTGTTTATAACATTGAGAGGTTTTCTAGGGCACATACTGAGTGAGAGCAGTGTTGAGAAGTCGGGGA
AAATGGTGACTACTTTTAGAGCAAGGCTGGGCATCAGCACCTGTCCAGCTCTACTTGTGTGATGTTTCAGGAACTCAGCCCCTTTTTCTG
CCTAGGATAAGGAGCTGAAAGATTAACTTGGATCTTCTAATGGTCCAAATCTTTTGGTCACAATAAAGAGTCTCCAAATTAGAGACTGCA
TGTTAGTTCTGGATGGATTTGGTGGCCTGACATGATACCCTGCCAGCTGTGAGGGGACCCCGTTTTTAAGATGCATGGCCAAGCTCTCTG
CAAATGGAAATGCTTACACTGGGTGTTGGGGATGTTTGCTACCTCCTGCTATTTTTGTGGTTTTGGTTCTCCCACTATGGTAGGACCCCT
GGCCAGCATTGTGGCTTGTCATGTCAGCCCCATTGACTACCTTCTCATGCTCTGAGGTACTACTGCCTCTGCAGCACAAATTTCTATTTC
TGTCAATAAAAGGAGATGAAAATATTCTATTGGAGTATGCCTTTCTTTTTTCTCTTCGTTTTTTCTTTCCTTTTCTAATTTTTTATATGA
AATAATGAGTAGTTTCTTCCTGAACCATTTGAGAGTGGTAAGTTGCAGATAGAATGCCCCTTTACCACTATATACCTGAATGTGTATTCT
TTCTTTTTAACACTTTTATTTTAAATATAAATTAAGAGAAATGGGCCAAAACCATTTGTATTGTTTAAAGAATAATTATAAACACACTTG

>78407_78407_6_RSF1-PAK1_RSF1_chr11_77475642_ENST00000360355_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=479AA_BP=0
MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKY
LIKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKP
KMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLV
GDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVG
TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELL

--------------------------------------------------------------
>78407_78407_7_RSF1-PAK1_RSF1_chr11_77475642_ENST00000360355_PAK1_chr11_77070062_ENST00000528203_length(transcript)=1859nt_BP=399nt
GATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCCCCC
ATCGCCTCCTCCTCCATCCTCCAGTTCAAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCGTGC
CCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGGGTG
CTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGCAAA
TCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGAATGTGAAGGCTGTGTCTGAGACTCCTGCAGTGCCACCAGTTTCAGAAGAT
GAGGATGATGATGATGATGATGCTACCCCACCACCAGTGATTGCTCCACGCCCAGAGCACACAAAATCTGTATACACACGGTCTGTGATT
GAACCACTTCCTGTCACTCCAACTCGGGACGTGGCTACATCTCCCATTTCACCTACTGAAAATAACACCACTCCACCAGATGCTTTGACC
CGGAATACTGAGAAGCAGAAGAAGAAGCCTAAAATGTCTGATGAGGAGATCTTGGAGAAATTACGAAGCATAGTGAGTGTGGGCGATCCT
AAGAAGAAATATACACGGTTTGAGAAGATTGGACAAGGTGCTTCAGGCACCGTGTACACAGCAATGGATGTGGCCACAGGACAGGAGGTG
GCCATTAAGCAGATGAATCTTCAGCAGCAGCCCAAGAAAGAGCTGATTATTAATGAGATCCTGGTCATGAGGGAAAACAAGAACCCAAAC
ATTGTGAATTACTTGGACAGTTACCTCGTGGGAGATGAGCTGTGGGTTGTTATGGAATACTTGGCTGGAGGCTCCTTGACAGATGTGGTG
ACAGAAACTTGCATGGATGAAGGCCAAATTGCAGCTGTGTGCCGTGAGTGTCTGCAGGCTCTGGAGTTCTTGCATTCGAACCAGGTCATT
CACAGAGACATCAAGAGTGACAATATTCTGTTGGGAATGGATGGCTCTGTCAAGCTAACTGACTTTGGATTCTGTGCACAGATAACCCCA
GAGCAGAGCAAACGGAGCACCATGGTAGGAACCCCATACTGGATGGCACCAGAGGTTGTGACACGAAAGGCCTATGGGCCCAAGGTTGAC
ATCTGGTCCCTGGGCATCATGGCCATCGAAATGATTGAAGGGGAGCCTCCATACCTCAATGAAAACCCTCTGAGAGCCTTGTACCTCATT
GCCACCAATGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTG
GAGAAGAGAGGTTCAGCTAAAGAGCTGCTACAGGTGAGAAAACTGAGGTTTCAAGTGTTTAGTAACTTTTCCATGATAGCTGCATCAATT
CCTGAAGATTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAAGGAGGCAACAAAGAACAATCACTAAAACCACACTCA
CCCCAGCCTCATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAGAAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGCTTC
TCCCATTTCCTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTAATC

>78407_78407_7_RSF1-PAK1_RSF1_chr11_77475642_ENST00000360355_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=487AA_BP=0
MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKY
LIKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKP
KMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLV
GDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVG
TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELL

--------------------------------------------------------------
>78407_78407_8_RSF1-PAK1_RSF1_chr11_77475642_ENST00000360355_PAK1_chr11_77070062_ENST00000530617_length(transcript)=2611nt_BP=399nt
GATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCCCCC
ATCGCCTCCTCCTCCATCCTCCAGTTCAAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCGTGC
CCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGGGTG
CTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGCAAA
TCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGAATGTGAAGGCTGTGTCTGAGACTCCTGCAGTGCCACCAGTTTCAGAAGAT
GAGGATGATGATGATGATGATGCTACCCCACCACCAGTGATTGCTCCACGCCCAGAGCACACAAAATCTGTATACACACGGTCTGTGATT
GAACCACTTCCTGTCACTCCAACTCGGGACGTGGCTACATCTCCCATTTCACCTACTGAAAATAACACCACTCCACCAGATGCTTTGACC
CGGAATACTGAGAAGCAGAAGAAGAAGCCTAAAATGTCTGATGAGGAGATCTTGGAGAAATTACGAAGCATAGTGAGTGTGGGCGATCCT
AAGAAGAAATATACACGGTTTGAGAAGATTGGACAAGGTGCTTCAGGCACCGTGTACACAGCAATGGATGTGGCCACAGGACAGGAGGTG
GCCATTAAGCAGATGAATCTTCAGCAGCAGCCCAAGAAAGAGCTGATTATTAATGAGATCCTGGTCATGAGGGAAAACAAGAACCCAAAC
ATTGTGAATTACTTGGACAGTTACCTCGTGGGAGATGAGCTGTGGGTTGTTATGGAATACTTGGCTGGAGGCTCCTTGACAGATGTGGTG
ACAGAAACTTGCATGGATGAAGGCCAAATTGCAGCTGTGTGCCGTGAGTGTCTGCAGGCTCTGGAGTTCTTGCATTCGAACCAGGTCATT
CACAGAGACATCAAGAGTGACAATATTCTGTTGGGAATGGATGGCTCTGTCAAGCTAACTGACTTTGGATTCTGTGCACAGATAACCCCA
GAGCAGAGCAAACGGAGCACCATGGTAGGAACCCCATACTGGATGGCACCAGAGGTTGTGACACGAAAGGCCTATGGGCCCAAGGTTGAC
ATCTGGTCCCTGGGCATCATGGCCATCGAAATGATTGAAGGGGAGCCTCCATACCTCAATGAAAACCCTCTGAGAGCCTTGTACCTCATT
GCCACCAATGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTG
GAGAAGAGAGGTTCAGCTAAAGAGCTGCTACAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCA
ACTGAATGACTAATCAGATGATGGCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGGTTTATGATTAAGGGTTTA
TATAAATAAATGTTTCTAGTCTTCCGTGTGTCAAAATCCTCACCTCCTTCATAACCATCTCCCACAATTAATTCTTGACTATATAAATTT
ATGGTTTGATAATATTATCAATTTGTAATCAATTGAGATTTCTTTAGTGCTTGCTTTTCTGTGACTCAACTGCCCAGACACCTCATTGTA
CTTGAAAACTGGAACAGCTTGGGAATGCCATGGGGTTTGATAATCTGCCAGGGACATGAAGAGGCTCAGCTTCCTGGACCATGACTTTGG
CTCAGCTGATCCTGACATGGGAGAACAACCACATTTTTCTTTGTGTGTGCTTCTAGCAGCTGTTCGGGAGGACCTTGACCCAATAGTGTT
CCCATGCTGTTTCTTGTGAAATGCTCTCGGCTATGTAGCAGCTTTTGATTCCCTGCATACCCTAGGCTGCTGCCCCTATCCTGTCCCTTG
TTTATAACATTGAGAGGTTTTCTAGGGCACATACTGAGTGAGAGCAGTGTTGAGAAGTCGGGGAAAATGGTGACTACTTTTAGAGCAAGG
CTGGGCATCAGCACCTGTCCAGCTCTACTTGTGTGATGTTTCAGGAACTCAGCCCCTTTTTCTGCCTAGGATAAGGAGCTGAAAGATTAA
CTTGGATCTTCTAATGGTCCAAATCTTTTGGTCACAATAAAGAGTCTCCAAATTAGAGACTGCATGTTAGTTCTGGATGGATTTGGTGGC
CTGACATGATACCCTGCCAGCTGTGAGGGGACCCCGTTTTTAAGATGCATGGCCAAGCTCTCTGCAAATGGAAATGCTTACACTGGGTGT
TGGGGATGTTTGCTACCTCCTGCTATTTTTGTGGTTTTGGTTCTCCCACTATGGTAGGACCCCTGGCCAGCATTGTGGCTTGTCATGTCA
GCCCCATTGACTACCTTCTCATGCTCTGAGGTACTACTGCCTCTGCAGCACAAATTTCTATTTCTGTCAATAAAAGGAGATGAAAATATT

>78407_78407_8_RSF1-PAK1_RSF1_chr11_77475642_ENST00000360355_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=456AA_BP=0
MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKY
LIKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKP
KMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLV
GDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVG
TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RSF1-PAK1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgenePAK1chr11:77475642chr11:77070062ENST00000278568416132_270159.0554.0CRIPAK
TgenePAK1chr11:77475642chr11:77070062ENST00000356341415132_270159.0546.0CRIPAK


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RSF1-PAK1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RSF1-PAK1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource