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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:RTTN-DOK6 (FusionGDB2 ID:78600) |
Fusion Gene Summary for RTTN-DOK6 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RTTN-DOK6 | Fusion gene ID: 78600 | Hgene | Tgene | Gene symbol | RTTN | DOK6 | Gene ID | 25914 | 220164 |
| Gene name | rotatin | docking protein 6 | |
| Synonyms | MSSP | DOK5L|HsT3226 | |
| Cytomap | 18q22.2 | 18q22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | rotatin | docking protein 6downstream of tyrosine kinase 6 | |
| Modification date | 20200322 | 20200313 | |
| UniProtAcc | . | Q6PKX4 | |
| Ensembl transtripts involved in fusion gene | ENST00000255674, ENST00000437017, ENST00000454359, ENST00000579986, | ENST00000584435, ENST00000382713, | |
| Fusion gene scores | * DoF score | 5 X 5 X 4=100 | 10 X 8 X 5=400 |
| # samples | 5 | 10 | |
| ** MAII score | log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/400*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RTTN [Title/Abstract] AND DOK6 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | RTTN(67833298)-DOK6(67424992), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across RTTN (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across DOK6 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | MESO | TCGA-SC-A6LN-01A | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + |
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Fusion Gene ORF analysis for RTTN-DOK6 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000255674 | ENST00000584435 | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + |
| 5CDS-intron | ENST00000437017 | ENST00000584435 | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + |
| 5CDS-intron | ENST00000454359 | ENST00000584435 | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + |
| In-frame | ENST00000255674 | ENST00000382713 | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + |
| In-frame | ENST00000437017 | ENST00000382713 | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + |
| In-frame | ENST00000454359 | ENST00000382713 | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + |
| intron-3CDS | ENST00000579986 | ENST00000382713 | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + |
| intron-intron | ENST00000579986 | ENST00000584435 | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000255674 | RTTN | chr18 | 67833298 | - | ENST00000382713 | DOK6 | chr18 | 67424992 | + | 10178 | 2216 | 287 | 2473 | 728 |
| ENST00000454359 | RTTN | chr18 | 67833298 | - | ENST00000382713 | DOK6 | chr18 | 67424992 | + | 9959 | 1997 | 68 | 2254 | 728 |
| ENST00000437017 | RTTN | chr18 | 67833298 | - | ENST00000382713 | DOK6 | chr18 | 67424992 | + | 9959 | 1997 | 68 | 2254 | 728 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000255674 | ENST00000382713 | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + | 0.001657195 | 0.99834275 |
| ENST00000454359 | ENST00000382713 | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + | 0.001662639 | 0.9983374 |
| ENST00000437017 | ENST00000382713 | RTTN | chr18 | 67833298 | - | DOK6 | chr18 | 67424992 | + | 0.001662639 | 0.9983374 |
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Fusion Genomic Features for RTTN-DOK6 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| RTTN | chr18 | 67833297 | - | DOK6 | chr18 | 67424991 | + | 0.000211396 | 0.9997886 |
| RTTN | chr18 | 67833297 | - | DOK6 | chr18 | 67424991 | + | 0.000211396 | 0.9997886 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for RTTN-DOK6 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:67833298/chr18:67424992) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | DOK6 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance. {ECO:0000269|PubMed:15286081}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | DOK6 | chr18:67833298 | chr18:67424992 | ENST00000382713 | 5 | 8 | 263_273 | 246 | 332.0 | Motif | Note=DKFBH motif |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | DOK6 | chr18:67833298 | chr18:67424992 | ENST00000382713 | 5 | 8 | 132_237 | 246 | 332.0 | Domain | IRS-type PTB | |
| Tgene | DOK6 | chr18:67833298 | chr18:67424992 | ENST00000382713 | 5 | 8 | 8_112 | 246 | 332.0 | Domain | Note=PH |
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Fusion Gene Sequence for RTTN-DOK6 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >78600_78600_1_RTTN-DOK6_RTTN_chr18_67833298_ENST00000255674_DOK6_chr18_67424992_ENST00000382713_length(transcript)=10178nt_BP=2216nt GGCCAACGCTGGTTCTATCCCTGCTTGTTGCTTTTTTTTTTCCCTCCGCTTCTTGCGACGGAGACTGCTGTCCAGGAAGTGCGCAGTAGT GATTCTAGAGAGGCTGGAAGCTCTCCTGGCGACGCTGGGGCCGCGAAGGGCTCACGTAATGACTCCTACTCCTGGTGAGCGCAGGCGTTG CGGAACTCACCGTCCCACAGGACGTGTTTCCGGGGGTACATTAATTGTGGCTGGACGCAGTGGCGCGGCAGTTTAATTCTCCGGCGGCTG CAGATTGACGGGACGAGATGGTCCTGGCAGGGCTCATCAGGAAACTCGGTCATCAGCTGGCCGAGATCAGGGAGCGCGCTCTCAAGAGTA TTCTCTGCAAGATTGAGCACAACTTAATCTGCTACGCTGATCTCATTCAGGAGAGGCAACTTTTTCTTCATTTGCTGGAATGGTTCAATT TCCCGTCCGTTCCGATGAAGGAAGAGGTTCTGAACCTGTTAAGCAGATTGGTTAAGTATCCCCCAGCAGTCCAACATTTGGTTGACGTTG GTGCAGTAGAGTTCTTATCTAAGCTTCGGTCTAATGTGGAGCCAAATCTGCAGGCTGAAATTGATGGCATTCTGGATGGACTTTTTCTTC TTCCTTCGGAAGTTCCTGCACTATCTTCTGCCTCATACCAAACCAATCAAACTGAATTGTCAAAAAACCCTGAAATCTTAACAGGATATT TTCCCCAAGACAAAAGTAATTTCCAGCAGATGGAAGTGCCGCCACGACCAGTGGTAAATCAGACTGTGAAGTGCTTGAAGTTTTCTACAT TTCCTTGGCTACCCCTGACCACCACAGACAGACATGTCCTCTCCTCTAATGAAAGCTCTTTAAGAAGTAGTAACCACACTTTAATCTGGA ACACCTGTGAACTATTGAAGGATGTTATCATGCAAGATTTTCCTGCTGAGATTTTCCTTCAAAGGCCAAAAATTGTTCAGAGCCTTTTAT CTCTGTTGAAACTGGCCTTTGGAGATGGAAAGCATCGCCTGGCATTACAGTCGGTGTCCTGCCTGCAGCAGCTGTGCATGTATTTAAGAA ACAGACTTAACTTTCACCGAGATCCAGGTTTTTTCTCCAATAAACACGACACAGTTTCCCAAAATTCTTCTTTGTCTTATTGTCATGAAG CAAGAGGTACTCATCATTCCCAGAATCCTTCCCCAGGAAGCAGCAGCCCTCGGCCTTCTGTGGTTGGGCGCACAGGCCAGCGACCCAGAG GAGATGGCCAGGACTGGGATGCAGCGTCCTCTAGTGGAAGTAGTAGTCATGCTCATGTAAACTCCAGGATATCCGTTCATTCACCTTTGG ATATGGGACACATAGATCTGCCAGAGCTGGAAACTGAAGACACATTGGAACTACAATTCCAGCAGCTCAGTCTTCCCCAGTTTTGTGTCT CCATTCTGGAATCAGCTGTTCCTCTCTTAAGAACAGGTAGCAGACAAGTGATAATAAGAGTTCTGGAATTGCTTACAGAGGATATGACAC TTATTGGTGAAGCAATTTCAACAGATATCTGGGATGACAGCAGCCTTTTTGGTATAGATATGAAGGAGAAACTACTCCTGGTGTTGGGAG CCCTTGGAGAAACCATGTGCTACCATAAAAGTAGTATCAGTTTGGAGCAGCCAGAGGTGATGCTTGTGCACCACAGAATGGCCTTTATCA GCATTTCCCTGTTTGCAGTTCGACTGCTACAAACGCTTCTCCCTGTTGAAAAGGCAAGCGAGTTTTTATCAGAGCCTATGTCAACAGCAT TATTTCTCCTTTCTTTGGACATGCCTATTTCTTTGGAATATCCAAATATTCATGAAGCTGTTGTGGCCTATTTGGAACAGCTGAATTCTG AAAACTACAGTATTTATAAACGAACTGCAGAGGCCGTTTATTCAATTGAATGCACCTGTAACTTCCTGTCTGATATTGGGAAAGAGGGAG AGAAGAATCTCTTAGAATTAGTGGAGCTGGCAGACCAAGCCTTGCGTAGCTTTTCCTATCATCAGCATTTCCCGCTAATAAAGGAAATCA TCAGCATTTGTTCAAAGATCTGGAAATCTGCTCAGGCCAGTCCATTACTACAAGGAGAAAGTCAGAAGGTGCTTCTCCATATGTTGTCTC ACCCATTGCCACGAGTGAAAGCTGAAACTTACCACTGCTGTCTGGAAATCACGAAGCTTCAGACAAGCTTGACTGAACCAATGACATTAT CCAAATCAATATCTCTTCCTCGCAGCGCGTACTGGCATCACATCACTCGTCAGAACAGCGTTGGTGAAATCTACAGTTTGCAAGGTCATG GGTTTGGTTCGTCAAAGATGTCTCGTGCACAGACATTTCCCAGCTACGCCCCAGAACAGAGTGAAGAGGCCCAGCAGCCGTTGTCGCGGT CCAGCAGCTATGGATTCAGCTACAGCTCCAGCCTCATCCAATGACACACAGAGAGCCGCTGTTGACTAGAGAGACAGTCTGTCCTGGACC CGTCTGTGGGGTCATTACCCTCTGCCTCCTGGAAGACCAATTGCAGTACAAATTGAAATGGGTCGGCTCTAGCCCCAGTCCCATTGGAAG GTTAAAAACTGGAGTTCTGCTTCCTTGATTCAGTGGCTAAGTCCTTTATTTATTGAATTTCTTTGGGGGAATCTATGTTTTACATAAATA GAATCCAAATCGTATGAACAGTTATTTAAATAAACAAAATTCTTTGGGTCTGACAGTAACAGAAACCTCAGCACTGGGAAAAGTTGCCCA CACTGGGGTATGCCTGGGTGATGGGCACCTCTCACTGACCTCACAGCGCAGTCCGCCCATCTGAGCACAGGGTCTGTCCTTAGACATAAT GGTGACCCTCCACAAGCTCTGTGGCTTTTAAAGTTCTGACAGGGATAAATACAGTAAGCTCTGCAAATGACATCGTAGCTGCATATAAAT AAACCCAGTGACAATTAAAGGAACATGAAATTCAGAACACACTATTAAGCAGGGCCCTGTAGCTCTACTCGTGTGTGTGTGTGCGTGTGT GTGTGTGTGTGTAGACAAATGGATATTGCTATATCCATCTATATATAACAAGTATATATCAAACATGTGCTGAGGGTGACAGGATATGCT CACTTAAATTGTTGAAAACCATAATTTGGTGCATTAAAGTTAAGATTGTTATGTTGAATAGCTATTTTTAAAATAGTGCTGTAAAAAAAA AAAAAAAAAAGGCTTCTTATTAGCAAAAGTATATGTAATCCAGTCTGTTCCTAACAAGTGTAAGCAAAAATGTGAGAAGGGGAACATTCA GAAGCAAAAGAACCAGTCTAGCTGTCCTACACATCATGTCATACCCTGTCTTTCTGGTGAGCGTTTCCTTGTTGCTGACAATGTTGCTCC CTGTGGCCATCCATCTGAGCTACGTGAGGAGGATTCCATGTGAACGCCGATCAGCTTCCATTTAACCTTGAGAGAAAAGAGAGGTTCTAA ATGAAGAACTCTTTAAGAAAGAAAGAATACACCCATAAAGAACTCAGCTATTTTGCAGTAAAGAGAAGAACAAAATGGGTACAGGATTGT GGATATCATAGATGCTGTTCTCACACAACCACTGGGGGCTTGTAATTTACTGTGTAACCAGAACTTGCAGGGCTTTATTTTTTCTTTTAC TGGACACAGGTTGTCTGAGATTATAAGAAATAAAATAGATCAATAATTTTCATCATCCCTGACACTGATTACAAACCTACAGTGTTTAAA GGGAGGTAGTGAATTCCACGGAAACTGAGTTTGGCTAATTCAGGTCAACAAAGATATATTTGCCCTTAATTCTGGAGTTAAGTAAAAATA AAAATTATCCTGCCTGAATCATCTGATGCTTTGTGCCTAAGATGGTTATCTCTCAAATACTCTAGGGTGGGTTTAAAGAACAGTGAGCTC AGGTCACGCAAGATGAAAACCCAGGTTTTTTTTTTCTTAATAGGAAAATTTTTTAAACTATCCAAATTAGTCTGTTGAAAGGGTACCTTT TTTGCTGATCTCTGATGAGTTGTCTTTTCATCCCTATCTGTAGCTTGAGTGCAGATTGACAATTCATTTCAGTGAATTACTACCGAATAA AAGTGGTTCCGGATCCCTCCTAGATAAATGTGCACTTACAGCAACTACCTAGGCTCTCCAAATCACTCCACTCGGTATGAAAACCCCATC AAGATACTAATCGTAAGAGTTAATGTGGCTGCAAAAAATAATTATCCTAAGCTTTCAGGGATAAAAAGAAAATTACCCAGGTTCTCTGCA CTGTGAATTTTGCTGACACAGCGGAGGAGCAGATGACTGGTTCCTACAACTGTACAGCCTTCCTTGAAATCATAGCTTTTGGGGTTAAAC ACTTGTGAATTTCTTTTGCACATGGCATTTGCTTTTGAAATGCCTTTAGTCAAATACACCAGAGCAACTCCCAGCTGAGACCATTTGAGC ACAGTTCCTAGTGGGGCCACATTCAGAGCAAGCCTCTCGCCGGCTCACTCAGTTGAGCTGTTGCTTAGACACCACAAGTTTCTACAAGGG ACTTATGGGGAACGGCCCTCAGGGGTCCTGGTTCACATCTCAGCTTTATTCATGTGCTGGAAGCACAAACAGCGAGTCCAGGGAGGGATT CTGCTAATCAGATGAGTCTGCTCTTGTGTCTCTTTCTTAGGAGACAAATACCTGTATGTAATTGCTTCAAGAACTCCATTTGGTTCTGAT CATTACCAATGAATATAACTGAAGGAGCACCAAAGATCAGGCATAACCTCGGGCCAGTTCATTCTGAAAATGATGTCGTAAAAAGAGTAT GTGTGAGAGAAATCTCCTTCCCAAGTTTTTAACCAGATCTCGTCACAATGAGGAGAATGCTATAATCTATCTCATGGTACATTTTTGGAG CTTAATTCTAGCATACTCCTCCAAGTACACTCACAATTGTAGCTGAGTCAAGACTGCTAAATGAACAGATAGGAGAACTTATATTAGACT AATATCCTTGACACGAAGCAGGGTTCATTGTAATAAAAACGGCAAACAGATAAATCTTCTACCAAAACCAAAGATGGAAAGTCACTGCAC CAGTCTCCTGGAACTTCATAAAATCAATTTCACTGGAGCAACCAGAAGGGTCATGGAGATGTATACCACTCGCTTGGGCTCGTAGGTTTT TGACTGGGGATGCCTCTACACTTTGTAAGTCATTTCTCCCTTCAAAAATTGTATTATATCTTTAATATATGTGTATTTTTCAATGCGAGG GAGGAATTACTATGAACCAAAGATATCTTTTGGCTCCTTCTGAAAGTGACTCAGTTTGAATTCCATTCAGATTTGTACAGATAAATAGAT GGTCACCATTTCTGCATCAGGTTGGAAGAGACCAATGATAAAGGAACCCAACGTAAGGAATAGCAGTTCTGAAAATAGACAAAGCCTAGA GGAGGTATCTATTTCACTGAGAGATTACACGAGGGGACTTATTTTTTATGTTCCCAATTTTTTCTTCTGATAATATTAATCAATGTACAC ATGATTGATGCATGATATTACACTTAAAATGCAGGAGAGTACAAAACAACCTTGATCCAATAGTTTCCTATTCTGGGGGGTGGGGGCAGA GGCGGAAAAGAAAACACATCTTTCACTTACTTATTGAACAAACAATAAGCACTCAGAACTAATTTATTTATGCAGGTTGCAAATATGTAT GAAGCAATAGGTTCTGGCCACTGCCACAATTTGAAATCAATAAAATAAGAAATATATATTTATATATGAGGGAAGATGCTGTTTGATAGA GCATGTGAAATCAATGGAAACATATTTATTAAAAGTAAACCTCACCTTTTTCACCAAATAGTAACTAGAGAACTAGTCCTAGTATCTTGC GTAATTCTTCTCTGTCTTCATTGGGAAATTATGTTTGAAAATCTTTCATCACCTATAAAATGGTGAGCCTCTTGTACTTTCTATTCAGTG TAGAAAGAGTGGACTGATAAATAACTTTACATTGTTGGTAGTAGTTTCTACAGATCCAGTTTATTGCATGTCGTATCTTTATTGTAGATA TTAAAAACACATGATAAAAATTGATGTGTGCCCCTCCTTGTTTGGCCAGTATCACAGAAAACTTTGTAAAAAAGCATGGGGACCCTACTC CCTAGATTATTTGAGCCATTTACTAAAATTGGCCATTAGTGATACAGTGAAAACAAGCTAAGGAAATGATATTCTCCTAAAAAGTTATAT TCCAGTTTTGATTATTATAACACAGCACAATAAATGGGCAGTATACGTCTAATGGAACTGAGATTTAAGGCTTTAACAATTCGTGTTTTA AAATATTATATTGAAGACTGCACAAAGAGAAAATTATACATGTTTCTCCAATCCTGTGATCATGTCTGTAAATACCTTGCAATTTCAAAT TACTTCATCCGTCATTAACTATATGATCTCCCAAACACAGCCTTCTCAAAATCGATAAAAATTTGCCACTGAATATGCATTAATAGCTAT AACAATGGGTGACATGCCACACAAATTTAGCTTATGCAATTTATGGGGTGTGTGTTTGCAGACTATGAAATGTATGAAGTGCAGTCTCCC ATGGAGAGAATAGAGAGGCAGGATGGCAACTAGTCATGAACGCAACAATTTAGGTTAAATGATAAAGAATACAATGAAATGTCCAGAGTA ACACTTGGTCTCTACCTTTCTAACATTCTAACCCAAGGCCAGTGTCATGGGCTTGGCTTTCTTCCCTGTCGCCTCATACTGAGTATGCAA TTTACAGAGGACATCTGTTGCTTTATGTCTTAAGGCCACTAGAGGAAGTCACTACATTCCCAACAAAGATGTGTCTTTCGGCTTAGTGAA AAACATTTAACAAGAAACAATGTGTAACCAAGTCCCCACAGTAAAATGTGTCTTCAGAAACATGAGAATCACTTTTATATAGCCAACCTC ATTTGAATTTTATCATGAACATAAATTATCGGTGAGACTGGTGTGCGGGGCTGGATCTGTGAGACAAGCTCACACTCTCATGTGTGCATT CTCTATTAACATATTTGGAAGATTGCCCACATTTTCTCTGCAGACCTGCCACAAATCCTTACCTTCTTACTGAAGAATGTGACTATTGTA GCATTCGTGCAATTATGCCAGCAGAGGAGGCACTAGACAGTTTATAGACTCTTATGGAAGTTGGGCACATTTCCCAGGCAGGTGGAATGC TAGCTAGATCTAGAAGCACCCTTAAAGGTCATGTAGAATCAAGGTCCCACTTTATGTTTCCCTTGGGAGAAAACTGAAACCCATGGATGC TGTAATTTGTTTAACGGCAAAGAAAGAGCCAAGAATTGTTTCTCGTAGTTCCAGGGTCCTGATCTAGGAATGTTTCCTTGGCTCCATGGC ATCTCCCAGTTTGACATAGTGGGAGCTGAGAAATGCCATATGGCCTCAAAATAAATAAACCCTTGTACATTTAAGTGTTTTCCCAGATTT TCAGATGCCTCTACTCTTGCTGAACTCATCACCAGCTGTATCAGTAGAGAGGTGTTATGGGGCAATTCATTAGATTTCTGGTAGGTCATG AATGGTTGGTATAAGCTTTATTTACTCATATATTGTCATCCAGTTCTTTGAAATTCAATCTTATCCTAAAGTGGTAGTCAAAGTAAAACA CATTAAGTAGGTGTTTGTGTTTAGCAGTCCTACTAATTCATCACAATCACATAGTAATTGTGATTATAATTTTTGGAATCTTTATCACTT TCTAGCACTTTACGGTGTCATTATTTATGGCATTTTTAACAACTTTGTTGCATAATTGATAACATCAGGGCTACATTTTTTTCATGTGAG CCTCAAGAAGCTTCCATTATCAACAAGAATTGGGGAAATGACTTTTTTACATTATAATACCTTATATATTAGGTTTTTCCTGATAATCTT CAGTAGACAATGATTTAAATTAACTGAAGTTTAAATAAGAAATATGTTAAAATTACTAAATAATATGAAAACCACATTATACTTGTAATT TTCAGACACTTTTCTCCTACCTTAAGATTTTAACATCTTGTAAATATTAATATTTGAAGGGGAGAGGAAAAATACATTTGTAGTAGAAAT ATTCCCTCTAACAATTCTGTTTAACTAGTAAGTTTTTTTTAAGTTATCTTCCATGCCTGCTTCCCTAGTCTGAACTCCACATTCCAGTTG TCAGAAGAATGAATGGATTTAAATTTTCTAATCATTATTTTGGGCCCATGTTAGCAGTTGAAACAATTAAGTTCCTCACTCTTTCCTGCT TTTAGGATGATTTTAGACTGTGAGCATAAAATCAACCCTTTCTGTCAGCACAGAATTGAACATCGAATGGAGCAAGGTCTACACTCTCAG CCTGTAGCTGTGCTAATGTTAGGATTGAATTGTTCTATTAATTCCCTCAAGAGACCCACAGCCTCAAAAGAGTTGCTTATTATCAGATGT CCGAAATTCAGAAACCCAAAGTCAGGCAAAGAAGGAAACTGAGATAATGATTTAATTTTTTTAAGTCACTGCAGGATTTCTCTCAAAGAA AACATCTGAAAATGGTTGAGAAAGTAGTTCCAGATCATTAACTATTTTACAGAGGGACTGAAAGCCAGGGAAAATAAAGAACAGAATGAT AGTAGTATCTTGATATTAAATTTGCATCAGAAATGAGCAAAATATGTCAATATGAAATAATTTGAAATCAAATTCAGATTCACATGTATA GTGCATAGTTCAAGAAATAATGCTTACTCTTGTAAAAAAAAAAAATATATATATATGTATCAGCAGGTAGAGTGTGGGAGCTCCAACTTT GTTGTGAAAGCTGATAACAGAGTATGATTCTTTCCAGTTACAAAATACTGTATTACTTTAGTTATAGCAAGCAGTACATAAATGACATCA ACAACTCAGGCTGCTCCCTGACATAAAAGCCAGTTCCATCTTTACTGCAGATGACAGGAGACTTTCCAAGACCTGCAGAGGCCCCCTCCA CCCCAACCTTAGTGCATGCTCACACACACACACACACACACACACACACACACACACACACACATTTTTGGCTTTTGACCCACTCTGTGT GTTCCACTGAAGTTATCTTTTCCTTAATAGATTCACACAGAATTACCCCATCCTGCAAAATCCTTATCCCTATGAATCTCTAAAATATAT TAAATAATGTGTTATATATTTGCTTTTTGTAAATCTTTATTTAATTAATTTATATATACTTTGTGAAGTCTTATACTGTACATCATAAAG CGATGTCATCTGTAGTTGGTTCAATATAATGTTTATGATCATTTTGATAAGAAATAACTTTGGACATTAGGCCCTTGTTAAGAAATAAAA CACCCATTATAAATTTGCTTCTGTTGGAAAATACATGATTTGGCATACTTCATTTTTAGTAACAATCTATTCTAGATAAATGATAATTTG GGGACATCTGTACTTAAAAACTAGCTGAACTACGTTTTGGGATGAGATGCAAAGCAACAGCTGTCCCTGGAACTGAAATGTGAATTTCTA GCAGAACAGAAAATATTATAATAATGAGGCAATAATAAAATTAGGAAATTAAATTATTTTTAAATCTGTCTGTGTGATTTTTCCCCTTGG TAAAAATACATGAAATACATAATTGAAAAATTACCTTCTTCTGAAGTCGTAGTTTTTAATCTTAACCATCAATAAATAAACCTATTGTTA ACAATGTCTTATTCATAATTCTAAAAAATTTACAAATGATATTGCTATGAGGTTGTGCACTATTAAAGTTTGCTCCATCACTTAAAGGTA AAGCAGTTCAAAAATACTACTTTACATCACAACTTTGCATGGCTGAGATTTTGAACAACTAAATTGATGGTTTTACCCACAAGTTATTTC ATAAAGCTAACACTGTAATATTACTTGGTTTTCTTATACTTTTGTTATCATGTGATGAAATGTAACTATGTAATTAAACAAAATTCTGAC AATCATATTCTGCTAATGTTTAAAATGTTACTTATTCCTTCACTTATTAGCTTGCTATTTTGAAAATAAAGTGAAAGAAGGCCCTTTATT >78600_78600_1_RTTN-DOK6_RTTN_chr18_67833298_ENST00000255674_DOK6_chr18_67424992_ENST00000382713_length(amino acids)=728AA_BP=638 MVLAGLIRKLGHQLAEIRERALKSILCKIEHNLICYADLIQERQLFLHLLEWFNFPSVPMKEEVLNLLSRLVKYPPAVQHLVDVGAVEFL SKLRSNVEPNLQAEIDGILDGLFLLPSEVPALSSASYQTNQTELSKNPEILTGYFPQDKSNFQQMEVPPRPVVNQTVKCLKFSTFPWLPL TTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDFPAEIFLQRPKIVQSLLSLLKLAFGDGKHRLALQSVSCLQQLCMYLRNRLNFH RDPGFFSNKHDTVSQNSSLSYCHEARGTHHSQNPSPGSSSPRPSVVGRTGQRPRGDGQDWDAASSSGSSSHAHVNSRISVHSPLDMGHID LPELETEDTLELQFQQLSLPQFCVSILESAVPLLRTGSRQVIIRVLELLTEDMTLIGEAISTDIWDDSSLFGIDMKEKLLLVLGALGETM CYHKSSISLEQPEVMLVHHRMAFISISLFAVRLLQTLLPVEKASEFLSEPMSTALFLLSLDMPISLEYPNIHEAVVAYLEQLNSENYSIY KRTAEAVYSIECTCNFLSDIGKEGEKNLLELVELADQALRSFSYHQHFPLIKEIISICSKIWKSAQASPLLQGESQKVLLHMLSHPLPRV KAETYHCCLEITKLQTSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQTFPSYAPEQSEEAQQPLSRSSSYGF -------------------------------------------------------------- >78600_78600_2_RTTN-DOK6_RTTN_chr18_67833298_ENST00000437017_DOK6_chr18_67424992_ENST00000382713_length(transcript)=9959nt_BP=1997nt ATTAATTGTGGCTGGACGCAGTGGCGCGGCAGTTTAATTCTCCGGCGGCTGCAGATTGACGGGACGAGATGGTCCTGGCAGGGCTCATCA GGAAACTCGGTCATCAGCTGGCCGAGATCAGGGAGCGCGCTCTCAAGAGTATTCTCTGCAAGATTGAGCACAACTTAATCTGCTACGCTG ATCTCATTCAGGAGAGGCAACTTTTTCTTCATTTGCTGGAATGGTTCAATTTCCCGTCCGTTCCGATGAAGGAAGAGGTTCTGAACCTGT TAAGCAGATTGGTTAAGTATCCCCCAGCAGTCCAACATTTGGTTGACGTTGGTGCAGTAGAGTTCTTATCTAAGCTTCGGTCTAATGTGG AGCCAAATCTGCAGGCTGAAATTGATGGCATTCTGGATGGACTTTTTCTTCTTCCTTCGGAAGTTCCTGCACTATCTTCTGCCTCATACC AAACCAATCAAACTGAATTGTCAAAAAACCCTGAAATCTTAACAGGATATTTTCCCCAAGACAAAAGTAATTTCCAGCAGATGGAAGTGC CGCCACGACCAGTGGTAAATCAGACTGTGAAGTGCTTGAAGTTTTCTACATTTCCTTGGCTACCCCTGACCACCACAGACAGACATGTCC TCTCCTCTAATGAAAGCTCTTTAAGAAGTAGTAACCACACTTTAATCTGGAACACCTGTGAACTATTGAAGGATGTTATCATGCAAGATT TTCCTGCTGAGATTTTCCTTCAAAGGCCAAAAATTGTTCAGAGCCTTTTATCTCTGTTGAAACTGGCCTTTGGAGATGGAAAGCATCGCC TGGCATTACAGTCGGTGTCCTGCCTGCAGCAGCTGTGCATGTATTTAAGAAACAGACTTAACTTTCACCGAGATCCAGGTTTTTTCTCCA ATAAACACGACACAGTTTCCCAAAATTCTTCTTTGTCTTATTGTCATGAAGCAAGAGGTACTCATCATTCCCAGAATCCTTCCCCAGGAA GCAGCAGCCCTCGGCCTTCTGTGGTTGGGCGCACAGGCCAGCGACCCAGAGGAGATGGCCAGGACTGGGATGCAGCGTCCTCTAGTGGAA GTAGTAGTCATGCTCATGTAAACTCCAGGATATCCGTTCATTCACCTTTGGATATGGGACACATAGATCTGCCAGAGCTGGAAACTGAAG ACACATTGGAACTACAATTCCAGCAGCTCAGTCTTCCCCAGTTTTGTGTCTCCATTCTGGAATCAGCTGTTCCTCTCTTAAGAACAGGTA GCAGACAAGTGATAATAAGAGTTCTGGAATTGCTTACAGAGGATATGACACTTATTGGTGAAGCAATTTCAACAGATATCTGGGATGACA GCAGCCTTTTTGGTATAGATATGAAGGAGAAACTACTCCTGGTGTTGGGAGCCCTTGGAGAAACCATGTGCTACCATAAAAGTAGTATCA GTTTGGAGCAGCCAGAGGTGATGCTTGTGCACCACAGAATGGCCTTTATCAGCATTTCCCTGTTTGCAGTTCGACTGCTACAAACGCTTC TCCCTGTTGAAAAGGCAAGCGAGTTTTTATCAGAGCCTATGTCAACAGCATTATTTCTCCTTTCTTTGGACATGCCTATTTCTTTGGAAT ATCCAAATATTCATGAAGCTGTTGTGGCCTATTTGGAACAGCTGAATTCTGAAAACTACAGTATTTATAAACGAACTGCAGAGGCCGTTT ATTCAATTGAATGCACCTGTAACTTCCTGTCTGATATTGGGAAAGAGGGAGAGAAGAATCTCTTAGAATTAGTGGAGCTGGCAGACCAAG CCTTGCGTAGCTTTTCCTATCATCAGCATTTCCCGCTAATAAAGGAAATCATCAGCATTTGTTCAAAGATCTGGAAATCTGCTCAGGCCA GTCCATTACTACAAGGAGAAAGTCAGAAGGTGCTTCTCCATATGTTGTCTCACCCATTGCCACGAGTGAAAGCTGAAACTTACCACTGCT GTCTGGAAATCACGAAGCTTCAGACAAGCTTGACTGAACCAATGACATTATCCAAATCAATATCTCTTCCTCGCAGCGCGTACTGGCATC ACATCACTCGTCAGAACAGCGTTGGTGAAATCTACAGTTTGCAAGGTCATGGGTTTGGTTCGTCAAAGATGTCTCGTGCACAGACATTTC CCAGCTACGCCCCAGAACAGAGTGAAGAGGCCCAGCAGCCGTTGTCGCGGTCCAGCAGCTATGGATTCAGCTACAGCTCCAGCCTCATCC AATGACACACAGAGAGCCGCTGTTGACTAGAGAGACAGTCTGTCCTGGACCCGTCTGTGGGGTCATTACCCTCTGCCTCCTGGAAGACCA ATTGCAGTACAAATTGAAATGGGTCGGCTCTAGCCCCAGTCCCATTGGAAGGTTAAAAACTGGAGTTCTGCTTCCTTGATTCAGTGGCTA AGTCCTTTATTTATTGAATTTCTTTGGGGGAATCTATGTTTTACATAAATAGAATCCAAATCGTATGAACAGTTATTTAAATAAACAAAA TTCTTTGGGTCTGACAGTAACAGAAACCTCAGCACTGGGAAAAGTTGCCCACACTGGGGTATGCCTGGGTGATGGGCACCTCTCACTGAC CTCACAGCGCAGTCCGCCCATCTGAGCACAGGGTCTGTCCTTAGACATAATGGTGACCCTCCACAAGCTCTGTGGCTTTTAAAGTTCTGA CAGGGATAAATACAGTAAGCTCTGCAAATGACATCGTAGCTGCATATAAATAAACCCAGTGACAATTAAAGGAACATGAAATTCAGAACA CACTATTAAGCAGGGCCCTGTAGCTCTACTCGTGTGTGTGTGTGCGTGTGTGTGTGTGTGTGTAGACAAATGGATATTGCTATATCCATC TATATATAACAAGTATATATCAAACATGTGCTGAGGGTGACAGGATATGCTCACTTAAATTGTTGAAAACCATAATTTGGTGCATTAAAG TTAAGATTGTTATGTTGAATAGCTATTTTTAAAATAGTGCTGTAAAAAAAAAAAAAAAAAAGGCTTCTTATTAGCAAAAGTATATGTAAT CCAGTCTGTTCCTAACAAGTGTAAGCAAAAATGTGAGAAGGGGAACATTCAGAAGCAAAAGAACCAGTCTAGCTGTCCTACACATCATGT CATACCCTGTCTTTCTGGTGAGCGTTTCCTTGTTGCTGACAATGTTGCTCCCTGTGGCCATCCATCTGAGCTACGTGAGGAGGATTCCAT GTGAACGCCGATCAGCTTCCATTTAACCTTGAGAGAAAAGAGAGGTTCTAAATGAAGAACTCTTTAAGAAAGAAAGAATACACCCATAAA GAACTCAGCTATTTTGCAGTAAAGAGAAGAACAAAATGGGTACAGGATTGTGGATATCATAGATGCTGTTCTCACACAACCACTGGGGGC TTGTAATTTACTGTGTAACCAGAACTTGCAGGGCTTTATTTTTTCTTTTACTGGACACAGGTTGTCTGAGATTATAAGAAATAAAATAGA TCAATAATTTTCATCATCCCTGACACTGATTACAAACCTACAGTGTTTAAAGGGAGGTAGTGAATTCCACGGAAACTGAGTTTGGCTAAT TCAGGTCAACAAAGATATATTTGCCCTTAATTCTGGAGTTAAGTAAAAATAAAAATTATCCTGCCTGAATCATCTGATGCTTTGTGCCTA AGATGGTTATCTCTCAAATACTCTAGGGTGGGTTTAAAGAACAGTGAGCTCAGGTCACGCAAGATGAAAACCCAGGTTTTTTTTTTCTTA ATAGGAAAATTTTTTAAACTATCCAAATTAGTCTGTTGAAAGGGTACCTTTTTTGCTGATCTCTGATGAGTTGTCTTTTCATCCCTATCT GTAGCTTGAGTGCAGATTGACAATTCATTTCAGTGAATTACTACCGAATAAAAGTGGTTCCGGATCCCTCCTAGATAAATGTGCACTTAC AGCAACTACCTAGGCTCTCCAAATCACTCCACTCGGTATGAAAACCCCATCAAGATACTAATCGTAAGAGTTAATGTGGCTGCAAAAAAT AATTATCCTAAGCTTTCAGGGATAAAAAGAAAATTACCCAGGTTCTCTGCACTGTGAATTTTGCTGACACAGCGGAGGAGCAGATGACTG GTTCCTACAACTGTACAGCCTTCCTTGAAATCATAGCTTTTGGGGTTAAACACTTGTGAATTTCTTTTGCACATGGCATTTGCTTTTGAA ATGCCTTTAGTCAAATACACCAGAGCAACTCCCAGCTGAGACCATTTGAGCACAGTTCCTAGTGGGGCCACATTCAGAGCAAGCCTCTCG CCGGCTCACTCAGTTGAGCTGTTGCTTAGACACCACAAGTTTCTACAAGGGACTTATGGGGAACGGCCCTCAGGGGTCCTGGTTCACATC TCAGCTTTATTCATGTGCTGGAAGCACAAACAGCGAGTCCAGGGAGGGATTCTGCTAATCAGATGAGTCTGCTCTTGTGTCTCTTTCTTA GGAGACAAATACCTGTATGTAATTGCTTCAAGAACTCCATTTGGTTCTGATCATTACCAATGAATATAACTGAAGGAGCACCAAAGATCA GGCATAACCTCGGGCCAGTTCATTCTGAAAATGATGTCGTAAAAAGAGTATGTGTGAGAGAAATCTCCTTCCCAAGTTTTTAACCAGATC TCGTCACAATGAGGAGAATGCTATAATCTATCTCATGGTACATTTTTGGAGCTTAATTCTAGCATACTCCTCCAAGTACACTCACAATTG TAGCTGAGTCAAGACTGCTAAATGAACAGATAGGAGAACTTATATTAGACTAATATCCTTGACACGAAGCAGGGTTCATTGTAATAAAAA CGGCAAACAGATAAATCTTCTACCAAAACCAAAGATGGAAAGTCACTGCACCAGTCTCCTGGAACTTCATAAAATCAATTTCACTGGAGC AACCAGAAGGGTCATGGAGATGTATACCACTCGCTTGGGCTCGTAGGTTTTTGACTGGGGATGCCTCTACACTTTGTAAGTCATTTCTCC CTTCAAAAATTGTATTATATCTTTAATATATGTGTATTTTTCAATGCGAGGGAGGAATTACTATGAACCAAAGATATCTTTTGGCTCCTT CTGAAAGTGACTCAGTTTGAATTCCATTCAGATTTGTACAGATAAATAGATGGTCACCATTTCTGCATCAGGTTGGAAGAGACCAATGAT AAAGGAACCCAACGTAAGGAATAGCAGTTCTGAAAATAGACAAAGCCTAGAGGAGGTATCTATTTCACTGAGAGATTACACGAGGGGACT TATTTTTTATGTTCCCAATTTTTTCTTCTGATAATATTAATCAATGTACACATGATTGATGCATGATATTACACTTAAAATGCAGGAGAG TACAAAACAACCTTGATCCAATAGTTTCCTATTCTGGGGGGTGGGGGCAGAGGCGGAAAAGAAAACACATCTTTCACTTACTTATTGAAC AAACAATAAGCACTCAGAACTAATTTATTTATGCAGGTTGCAAATATGTATGAAGCAATAGGTTCTGGCCACTGCCACAATTTGAAATCA ATAAAATAAGAAATATATATTTATATATGAGGGAAGATGCTGTTTGATAGAGCATGTGAAATCAATGGAAACATATTTATTAAAAGTAAA CCTCACCTTTTTCACCAAATAGTAACTAGAGAACTAGTCCTAGTATCTTGCGTAATTCTTCTCTGTCTTCATTGGGAAATTATGTTTGAA AATCTTTCATCACCTATAAAATGGTGAGCCTCTTGTACTTTCTATTCAGTGTAGAAAGAGTGGACTGATAAATAACTTTACATTGTTGGT AGTAGTTTCTACAGATCCAGTTTATTGCATGTCGTATCTTTATTGTAGATATTAAAAACACATGATAAAAATTGATGTGTGCCCCTCCTT GTTTGGCCAGTATCACAGAAAACTTTGTAAAAAAGCATGGGGACCCTACTCCCTAGATTATTTGAGCCATTTACTAAAATTGGCCATTAG TGATACAGTGAAAACAAGCTAAGGAAATGATATTCTCCTAAAAAGTTATATTCCAGTTTTGATTATTATAACACAGCACAATAAATGGGC AGTATACGTCTAATGGAACTGAGATTTAAGGCTTTAACAATTCGTGTTTTAAAATATTATATTGAAGACTGCACAAAGAGAAAATTATAC ATGTTTCTCCAATCCTGTGATCATGTCTGTAAATACCTTGCAATTTCAAATTACTTCATCCGTCATTAACTATATGATCTCCCAAACACA GCCTTCTCAAAATCGATAAAAATTTGCCACTGAATATGCATTAATAGCTATAACAATGGGTGACATGCCACACAAATTTAGCTTATGCAA TTTATGGGGTGTGTGTTTGCAGACTATGAAATGTATGAAGTGCAGTCTCCCATGGAGAGAATAGAGAGGCAGGATGGCAACTAGTCATGA ACGCAACAATTTAGGTTAAATGATAAAGAATACAATGAAATGTCCAGAGTAACACTTGGTCTCTACCTTTCTAACATTCTAACCCAAGGC CAGTGTCATGGGCTTGGCTTTCTTCCCTGTCGCCTCATACTGAGTATGCAATTTACAGAGGACATCTGTTGCTTTATGTCTTAAGGCCAC TAGAGGAAGTCACTACATTCCCAACAAAGATGTGTCTTTCGGCTTAGTGAAAAACATTTAACAAGAAACAATGTGTAACCAAGTCCCCAC AGTAAAATGTGTCTTCAGAAACATGAGAATCACTTTTATATAGCCAACCTCATTTGAATTTTATCATGAACATAAATTATCGGTGAGACT GGTGTGCGGGGCTGGATCTGTGAGACAAGCTCACACTCTCATGTGTGCATTCTCTATTAACATATTTGGAAGATTGCCCACATTTTCTCT GCAGACCTGCCACAAATCCTTACCTTCTTACTGAAGAATGTGACTATTGTAGCATTCGTGCAATTATGCCAGCAGAGGAGGCACTAGACA GTTTATAGACTCTTATGGAAGTTGGGCACATTTCCCAGGCAGGTGGAATGCTAGCTAGATCTAGAAGCACCCTTAAAGGTCATGTAGAAT CAAGGTCCCACTTTATGTTTCCCTTGGGAGAAAACTGAAACCCATGGATGCTGTAATTTGTTTAACGGCAAAGAAAGAGCCAAGAATTGT TTCTCGTAGTTCCAGGGTCCTGATCTAGGAATGTTTCCTTGGCTCCATGGCATCTCCCAGTTTGACATAGTGGGAGCTGAGAAATGCCAT ATGGCCTCAAAATAAATAAACCCTTGTACATTTAAGTGTTTTCCCAGATTTTCAGATGCCTCTACTCTTGCTGAACTCATCACCAGCTGT ATCAGTAGAGAGGTGTTATGGGGCAATTCATTAGATTTCTGGTAGGTCATGAATGGTTGGTATAAGCTTTATTTACTCATATATTGTCAT CCAGTTCTTTGAAATTCAATCTTATCCTAAAGTGGTAGTCAAAGTAAAACACATTAAGTAGGTGTTTGTGTTTAGCAGTCCTACTAATTC ATCACAATCACATAGTAATTGTGATTATAATTTTTGGAATCTTTATCACTTTCTAGCACTTTACGGTGTCATTATTTATGGCATTTTTAA CAACTTTGTTGCATAATTGATAACATCAGGGCTACATTTTTTTCATGTGAGCCTCAAGAAGCTTCCATTATCAACAAGAATTGGGGAAAT GACTTTTTTACATTATAATACCTTATATATTAGGTTTTTCCTGATAATCTTCAGTAGACAATGATTTAAATTAACTGAAGTTTAAATAAG AAATATGTTAAAATTACTAAATAATATGAAAACCACATTATACTTGTAATTTTCAGACACTTTTCTCCTACCTTAAGATTTTAACATCTT GTAAATATTAATATTTGAAGGGGAGAGGAAAAATACATTTGTAGTAGAAATATTCCCTCTAACAATTCTGTTTAACTAGTAAGTTTTTTT TAAGTTATCTTCCATGCCTGCTTCCCTAGTCTGAACTCCACATTCCAGTTGTCAGAAGAATGAATGGATTTAAATTTTCTAATCATTATT TTGGGCCCATGTTAGCAGTTGAAACAATTAAGTTCCTCACTCTTTCCTGCTTTTAGGATGATTTTAGACTGTGAGCATAAAATCAACCCT TTCTGTCAGCACAGAATTGAACATCGAATGGAGCAAGGTCTACACTCTCAGCCTGTAGCTGTGCTAATGTTAGGATTGAATTGTTCTATT AATTCCCTCAAGAGACCCACAGCCTCAAAAGAGTTGCTTATTATCAGATGTCCGAAATTCAGAAACCCAAAGTCAGGCAAAGAAGGAAAC TGAGATAATGATTTAATTTTTTTAAGTCACTGCAGGATTTCTCTCAAAGAAAACATCTGAAAATGGTTGAGAAAGTAGTTCCAGATCATT AACTATTTTACAGAGGGACTGAAAGCCAGGGAAAATAAAGAACAGAATGATAGTAGTATCTTGATATTAAATTTGCATCAGAAATGAGCA AAATATGTCAATATGAAATAATTTGAAATCAAATTCAGATTCACATGTATAGTGCATAGTTCAAGAAATAATGCTTACTCTTGTAAAAAA AAAAAATATATATATATGTATCAGCAGGTAGAGTGTGGGAGCTCCAACTTTGTTGTGAAAGCTGATAACAGAGTATGATTCTTTCCAGTT ACAAAATACTGTATTACTTTAGTTATAGCAAGCAGTACATAAATGACATCAACAACTCAGGCTGCTCCCTGACATAAAAGCCAGTTCCAT CTTTACTGCAGATGACAGGAGACTTTCCAAGACCTGCAGAGGCCCCCTCCACCCCAACCTTAGTGCATGCTCACACACACACACACACAC ACACACACACACACACACACACACATTTTTGGCTTTTGACCCACTCTGTGTGTTCCACTGAAGTTATCTTTTCCTTAATAGATTCACACA GAATTACCCCATCCTGCAAAATCCTTATCCCTATGAATCTCTAAAATATATTAAATAATGTGTTATATATTTGCTTTTTGTAAATCTTTA TTTAATTAATTTATATATACTTTGTGAAGTCTTATACTGTACATCATAAAGCGATGTCATCTGTAGTTGGTTCAATATAATGTTTATGAT CATTTTGATAAGAAATAACTTTGGACATTAGGCCCTTGTTAAGAAATAAAACACCCATTATAAATTTGCTTCTGTTGGAAAATACATGAT TTGGCATACTTCATTTTTAGTAACAATCTATTCTAGATAAATGATAATTTGGGGACATCTGTACTTAAAAACTAGCTGAACTACGTTTTG GGATGAGATGCAAAGCAACAGCTGTCCCTGGAACTGAAATGTGAATTTCTAGCAGAACAGAAAATATTATAATAATGAGGCAATAATAAA ATTAGGAAATTAAATTATTTTTAAATCTGTCTGTGTGATTTTTCCCCTTGGTAAAAATACATGAAATACATAATTGAAAAATTACCTTCT TCTGAAGTCGTAGTTTTTAATCTTAACCATCAATAAATAAACCTATTGTTAACAATGTCTTATTCATAATTCTAAAAAATTTACAAATGA TATTGCTATGAGGTTGTGCACTATTAAAGTTTGCTCCATCACTTAAAGGTAAAGCAGTTCAAAAATACTACTTTACATCACAACTTTGCA TGGCTGAGATTTTGAACAACTAAATTGATGGTTTTACCCACAAGTTATTTCATAAAGCTAACACTGTAATATTACTTGGTTTTCTTATAC TTTTGTTATCATGTGATGAAATGTAACTATGTAATTAAACAAAATTCTGACAATCATATTCTGCTAATGTTTAAAATGTTACTTATTCCT >78600_78600_2_RTTN-DOK6_RTTN_chr18_67833298_ENST00000437017_DOK6_chr18_67424992_ENST00000382713_length(amino acids)=728AA_BP=638 MVLAGLIRKLGHQLAEIRERALKSILCKIEHNLICYADLIQERQLFLHLLEWFNFPSVPMKEEVLNLLSRLVKYPPAVQHLVDVGAVEFL SKLRSNVEPNLQAEIDGILDGLFLLPSEVPALSSASYQTNQTELSKNPEILTGYFPQDKSNFQQMEVPPRPVVNQTVKCLKFSTFPWLPL TTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDFPAEIFLQRPKIVQSLLSLLKLAFGDGKHRLALQSVSCLQQLCMYLRNRLNFH RDPGFFSNKHDTVSQNSSLSYCHEARGTHHSQNPSPGSSSPRPSVVGRTGQRPRGDGQDWDAASSSGSSSHAHVNSRISVHSPLDMGHID LPELETEDTLELQFQQLSLPQFCVSILESAVPLLRTGSRQVIIRVLELLTEDMTLIGEAISTDIWDDSSLFGIDMKEKLLLVLGALGETM CYHKSSISLEQPEVMLVHHRMAFISISLFAVRLLQTLLPVEKASEFLSEPMSTALFLLSLDMPISLEYPNIHEAVVAYLEQLNSENYSIY KRTAEAVYSIECTCNFLSDIGKEGEKNLLELVELADQALRSFSYHQHFPLIKEIISICSKIWKSAQASPLLQGESQKVLLHMLSHPLPRV KAETYHCCLEITKLQTSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQTFPSYAPEQSEEAQQPLSRSSSYGF -------------------------------------------------------------- >78600_78600_3_RTTN-DOK6_RTTN_chr18_67833298_ENST00000454359_DOK6_chr18_67424992_ENST00000382713_length(transcript)=9959nt_BP=1997nt ATTAATTGTGGCTGGACGCAGTGGCGCGGCAGTTTAATTCTCCGGCGGCTGCAGATTGACGGGACGAGATGGTCCTGGCAGGGCTCATCA GGAAACTCGGTCATCAGCTGGCCGAGATCAGGGAGCGCGCTCTCAAGAGTATTCTCTGCAAGATTGAGCACAACTTAATCTGCTACGCTG ATCTCATTCAGGAGAGGCAACTTTTTCTTCATTTGCTGGAATGGTTCAATTTCCCGTCCGTTCCGATGAAGGAAGAGGTTCTGAACCTGT TAAGCAGATTGGTTAAGTATCCCCCAGCAGTCCAACATTTGGTTGACGTTGGTGCAGTAGAGTTCTTATCTAAGCTTCGGTCTAATGTGG AGCCAAATCTGCAGGCTGAAATTGATGGCATTCTGGATGGACTTTTTCTTCTTCCTTCGGAAGTTCCTGCACTATCTTCTGCCTCATACC AAACCAATCAAACTGAATTGTCAAAAAACCCTGAAATCTTAACAGGATATTTTCCCCAAGACAAAAGTAATTTCCAGCAGATGGAAGTGC CGCCACGACCAGTGGTAAATCAGACTGTGAAGTGCTTGAAGTTTTCTACATTTCCTTGGCTACCCCTGACCACCACAGACAGACATGTCC TCTCCTCTAATGAAAGCTCTTTAAGAAGTAGTAACCACACTTTAATCTGGAACACCTGTGAACTATTGAAGGATGTTATCATGCAAGATT TTCCTGCTGAGATTTTCCTTCAAAGGCCAAAAATTGTTCAGAGCCTTTTATCTCTGTTGAAACTGGCCTTTGGAGATGGAAAGCATCGCC TGGCATTACAGTCGGTGTCCTGCCTGCAGCAGCTGTGCATGTATTTAAGAAACAGACTTAACTTTCACCGAGATCCAGGTTTTTTCTCCA ATAAACACGACACAGTTTCCCAAAATTCTTCTTTGTCTTATTGTCATGAAGCAAGAGGTACTCATCATTCCCAGAATCCTTCCCCAGGAA GCAGCAGCCCTCGGCCTTCTGTGGTTGGGCGCACAGGCCAGCGACCCAGAGGAGATGGCCAGGACTGGGATGCAGCGTCCTCTAGTGGAA GTAGTAGTCATGCTCATGTAAACTCCAGGATATCCGTTCATTCACCTTTGGATATGGGACACATAGATCTGCCAGAGCTGGAAACTGAAG ACACATTGGAACTACAATTCCAGCAGCTCAGTCTTCCCCAGTTTTGTGTCTCCATTCTGGAATCAGCTGTTCCTCTCTTAAGAACAGGTA GCAGACAAGTGATAATAAGAGTTCTGGAATTGCTTACAGAGGATATGACACTTATTGGTGAAGCAATTTCAACAGATATCTGGGATGACA GCAGCCTTTTTGGTATAGATATGAAGGAGAAACTACTCCTGGTGTTGGGAGCCCTTGGAGAAACCATGTGCTACCATAAAAGTAGTATCA GTTTGGAGCAGCCAGAGGTGATGCTTGTGCACCACAGAATGGCCTTTATCAGCATTTCCCTGTTTGCAGTTCGACTGCTACAAACGCTTC TCCCTGTTGAAAAGGCAAGCGAGTTTTTATCAGAGCCTATGTCAACAGCATTATTTCTCCTTTCTTTGGACATGCCTATTTCTTTGGAAT ATCCAAATATTCATGAAGCTGTTGTGGCCTATTTGGAACAGCTGAATTCTGAAAACTACAGTATTTATAAACGAACTGCAGAGGCCGTTT ATTCAATTGAATGCACCTGTAACTTCCTGTCTGATATTGGGAAAGAGGGAGAGAAGAATCTCTTAGAATTAGTGGAGCTGGCAGACCAAG CCTTGCGTAGCTTTTCCTATCATCAGCATTTCCCGCTAATAAAGGAAATCATCAGCATTTGTTCAAAGATCTGGAAATCTGCTCAGGCCA GTCCATTACTACAAGGAGAAAGTCAGAAGGTGCTTCTCCATATGTTGTCTCACCCATTGCCACGAGTGAAAGCTGAAACTTACCACTGCT GTCTGGAAATCACGAAGCTTCAGACAAGCTTGACTGAACCAATGACATTATCCAAATCAATATCTCTTCCTCGCAGCGCGTACTGGCATC ACATCACTCGTCAGAACAGCGTTGGTGAAATCTACAGTTTGCAAGGTCATGGGTTTGGTTCGTCAAAGATGTCTCGTGCACAGACATTTC CCAGCTACGCCCCAGAACAGAGTGAAGAGGCCCAGCAGCCGTTGTCGCGGTCCAGCAGCTATGGATTCAGCTACAGCTCCAGCCTCATCC AATGACACACAGAGAGCCGCTGTTGACTAGAGAGACAGTCTGTCCTGGACCCGTCTGTGGGGTCATTACCCTCTGCCTCCTGGAAGACCA ATTGCAGTACAAATTGAAATGGGTCGGCTCTAGCCCCAGTCCCATTGGAAGGTTAAAAACTGGAGTTCTGCTTCCTTGATTCAGTGGCTA AGTCCTTTATTTATTGAATTTCTTTGGGGGAATCTATGTTTTACATAAATAGAATCCAAATCGTATGAACAGTTATTTAAATAAACAAAA TTCTTTGGGTCTGACAGTAACAGAAACCTCAGCACTGGGAAAAGTTGCCCACACTGGGGTATGCCTGGGTGATGGGCACCTCTCACTGAC CTCACAGCGCAGTCCGCCCATCTGAGCACAGGGTCTGTCCTTAGACATAATGGTGACCCTCCACAAGCTCTGTGGCTTTTAAAGTTCTGA CAGGGATAAATACAGTAAGCTCTGCAAATGACATCGTAGCTGCATATAAATAAACCCAGTGACAATTAAAGGAACATGAAATTCAGAACA CACTATTAAGCAGGGCCCTGTAGCTCTACTCGTGTGTGTGTGTGCGTGTGTGTGTGTGTGTGTAGACAAATGGATATTGCTATATCCATC TATATATAACAAGTATATATCAAACATGTGCTGAGGGTGACAGGATATGCTCACTTAAATTGTTGAAAACCATAATTTGGTGCATTAAAG TTAAGATTGTTATGTTGAATAGCTATTTTTAAAATAGTGCTGTAAAAAAAAAAAAAAAAAAGGCTTCTTATTAGCAAAAGTATATGTAAT CCAGTCTGTTCCTAACAAGTGTAAGCAAAAATGTGAGAAGGGGAACATTCAGAAGCAAAAGAACCAGTCTAGCTGTCCTACACATCATGT CATACCCTGTCTTTCTGGTGAGCGTTTCCTTGTTGCTGACAATGTTGCTCCCTGTGGCCATCCATCTGAGCTACGTGAGGAGGATTCCAT GTGAACGCCGATCAGCTTCCATTTAACCTTGAGAGAAAAGAGAGGTTCTAAATGAAGAACTCTTTAAGAAAGAAAGAATACACCCATAAA GAACTCAGCTATTTTGCAGTAAAGAGAAGAACAAAATGGGTACAGGATTGTGGATATCATAGATGCTGTTCTCACACAACCACTGGGGGC TTGTAATTTACTGTGTAACCAGAACTTGCAGGGCTTTATTTTTTCTTTTACTGGACACAGGTTGTCTGAGATTATAAGAAATAAAATAGA TCAATAATTTTCATCATCCCTGACACTGATTACAAACCTACAGTGTTTAAAGGGAGGTAGTGAATTCCACGGAAACTGAGTTTGGCTAAT TCAGGTCAACAAAGATATATTTGCCCTTAATTCTGGAGTTAAGTAAAAATAAAAATTATCCTGCCTGAATCATCTGATGCTTTGTGCCTA AGATGGTTATCTCTCAAATACTCTAGGGTGGGTTTAAAGAACAGTGAGCTCAGGTCACGCAAGATGAAAACCCAGGTTTTTTTTTTCTTA ATAGGAAAATTTTTTAAACTATCCAAATTAGTCTGTTGAAAGGGTACCTTTTTTGCTGATCTCTGATGAGTTGTCTTTTCATCCCTATCT GTAGCTTGAGTGCAGATTGACAATTCATTTCAGTGAATTACTACCGAATAAAAGTGGTTCCGGATCCCTCCTAGATAAATGTGCACTTAC AGCAACTACCTAGGCTCTCCAAATCACTCCACTCGGTATGAAAACCCCATCAAGATACTAATCGTAAGAGTTAATGTGGCTGCAAAAAAT AATTATCCTAAGCTTTCAGGGATAAAAAGAAAATTACCCAGGTTCTCTGCACTGTGAATTTTGCTGACACAGCGGAGGAGCAGATGACTG GTTCCTACAACTGTACAGCCTTCCTTGAAATCATAGCTTTTGGGGTTAAACACTTGTGAATTTCTTTTGCACATGGCATTTGCTTTTGAA ATGCCTTTAGTCAAATACACCAGAGCAACTCCCAGCTGAGACCATTTGAGCACAGTTCCTAGTGGGGCCACATTCAGAGCAAGCCTCTCG CCGGCTCACTCAGTTGAGCTGTTGCTTAGACACCACAAGTTTCTACAAGGGACTTATGGGGAACGGCCCTCAGGGGTCCTGGTTCACATC TCAGCTTTATTCATGTGCTGGAAGCACAAACAGCGAGTCCAGGGAGGGATTCTGCTAATCAGATGAGTCTGCTCTTGTGTCTCTTTCTTA GGAGACAAATACCTGTATGTAATTGCTTCAAGAACTCCATTTGGTTCTGATCATTACCAATGAATATAACTGAAGGAGCACCAAAGATCA GGCATAACCTCGGGCCAGTTCATTCTGAAAATGATGTCGTAAAAAGAGTATGTGTGAGAGAAATCTCCTTCCCAAGTTTTTAACCAGATC TCGTCACAATGAGGAGAATGCTATAATCTATCTCATGGTACATTTTTGGAGCTTAATTCTAGCATACTCCTCCAAGTACACTCACAATTG TAGCTGAGTCAAGACTGCTAAATGAACAGATAGGAGAACTTATATTAGACTAATATCCTTGACACGAAGCAGGGTTCATTGTAATAAAAA CGGCAAACAGATAAATCTTCTACCAAAACCAAAGATGGAAAGTCACTGCACCAGTCTCCTGGAACTTCATAAAATCAATTTCACTGGAGC AACCAGAAGGGTCATGGAGATGTATACCACTCGCTTGGGCTCGTAGGTTTTTGACTGGGGATGCCTCTACACTTTGTAAGTCATTTCTCC CTTCAAAAATTGTATTATATCTTTAATATATGTGTATTTTTCAATGCGAGGGAGGAATTACTATGAACCAAAGATATCTTTTGGCTCCTT CTGAAAGTGACTCAGTTTGAATTCCATTCAGATTTGTACAGATAAATAGATGGTCACCATTTCTGCATCAGGTTGGAAGAGACCAATGAT AAAGGAACCCAACGTAAGGAATAGCAGTTCTGAAAATAGACAAAGCCTAGAGGAGGTATCTATTTCACTGAGAGATTACACGAGGGGACT TATTTTTTATGTTCCCAATTTTTTCTTCTGATAATATTAATCAATGTACACATGATTGATGCATGATATTACACTTAAAATGCAGGAGAG TACAAAACAACCTTGATCCAATAGTTTCCTATTCTGGGGGGTGGGGGCAGAGGCGGAAAAGAAAACACATCTTTCACTTACTTATTGAAC AAACAATAAGCACTCAGAACTAATTTATTTATGCAGGTTGCAAATATGTATGAAGCAATAGGTTCTGGCCACTGCCACAATTTGAAATCA ATAAAATAAGAAATATATATTTATATATGAGGGAAGATGCTGTTTGATAGAGCATGTGAAATCAATGGAAACATATTTATTAAAAGTAAA CCTCACCTTTTTCACCAAATAGTAACTAGAGAACTAGTCCTAGTATCTTGCGTAATTCTTCTCTGTCTTCATTGGGAAATTATGTTTGAA AATCTTTCATCACCTATAAAATGGTGAGCCTCTTGTACTTTCTATTCAGTGTAGAAAGAGTGGACTGATAAATAACTTTACATTGTTGGT AGTAGTTTCTACAGATCCAGTTTATTGCATGTCGTATCTTTATTGTAGATATTAAAAACACATGATAAAAATTGATGTGTGCCCCTCCTT GTTTGGCCAGTATCACAGAAAACTTTGTAAAAAAGCATGGGGACCCTACTCCCTAGATTATTTGAGCCATTTACTAAAATTGGCCATTAG TGATACAGTGAAAACAAGCTAAGGAAATGATATTCTCCTAAAAAGTTATATTCCAGTTTTGATTATTATAACACAGCACAATAAATGGGC AGTATACGTCTAATGGAACTGAGATTTAAGGCTTTAACAATTCGTGTTTTAAAATATTATATTGAAGACTGCACAAAGAGAAAATTATAC ATGTTTCTCCAATCCTGTGATCATGTCTGTAAATACCTTGCAATTTCAAATTACTTCATCCGTCATTAACTATATGATCTCCCAAACACA GCCTTCTCAAAATCGATAAAAATTTGCCACTGAATATGCATTAATAGCTATAACAATGGGTGACATGCCACACAAATTTAGCTTATGCAA TTTATGGGGTGTGTGTTTGCAGACTATGAAATGTATGAAGTGCAGTCTCCCATGGAGAGAATAGAGAGGCAGGATGGCAACTAGTCATGA ACGCAACAATTTAGGTTAAATGATAAAGAATACAATGAAATGTCCAGAGTAACACTTGGTCTCTACCTTTCTAACATTCTAACCCAAGGC CAGTGTCATGGGCTTGGCTTTCTTCCCTGTCGCCTCATACTGAGTATGCAATTTACAGAGGACATCTGTTGCTTTATGTCTTAAGGCCAC TAGAGGAAGTCACTACATTCCCAACAAAGATGTGTCTTTCGGCTTAGTGAAAAACATTTAACAAGAAACAATGTGTAACCAAGTCCCCAC AGTAAAATGTGTCTTCAGAAACATGAGAATCACTTTTATATAGCCAACCTCATTTGAATTTTATCATGAACATAAATTATCGGTGAGACT GGTGTGCGGGGCTGGATCTGTGAGACAAGCTCACACTCTCATGTGTGCATTCTCTATTAACATATTTGGAAGATTGCCCACATTTTCTCT GCAGACCTGCCACAAATCCTTACCTTCTTACTGAAGAATGTGACTATTGTAGCATTCGTGCAATTATGCCAGCAGAGGAGGCACTAGACA GTTTATAGACTCTTATGGAAGTTGGGCACATTTCCCAGGCAGGTGGAATGCTAGCTAGATCTAGAAGCACCCTTAAAGGTCATGTAGAAT CAAGGTCCCACTTTATGTTTCCCTTGGGAGAAAACTGAAACCCATGGATGCTGTAATTTGTTTAACGGCAAAGAAAGAGCCAAGAATTGT TTCTCGTAGTTCCAGGGTCCTGATCTAGGAATGTTTCCTTGGCTCCATGGCATCTCCCAGTTTGACATAGTGGGAGCTGAGAAATGCCAT ATGGCCTCAAAATAAATAAACCCTTGTACATTTAAGTGTTTTCCCAGATTTTCAGATGCCTCTACTCTTGCTGAACTCATCACCAGCTGT ATCAGTAGAGAGGTGTTATGGGGCAATTCATTAGATTTCTGGTAGGTCATGAATGGTTGGTATAAGCTTTATTTACTCATATATTGTCAT CCAGTTCTTTGAAATTCAATCTTATCCTAAAGTGGTAGTCAAAGTAAAACACATTAAGTAGGTGTTTGTGTTTAGCAGTCCTACTAATTC ATCACAATCACATAGTAATTGTGATTATAATTTTTGGAATCTTTATCACTTTCTAGCACTTTACGGTGTCATTATTTATGGCATTTTTAA CAACTTTGTTGCATAATTGATAACATCAGGGCTACATTTTTTTCATGTGAGCCTCAAGAAGCTTCCATTATCAACAAGAATTGGGGAAAT GACTTTTTTACATTATAATACCTTATATATTAGGTTTTTCCTGATAATCTTCAGTAGACAATGATTTAAATTAACTGAAGTTTAAATAAG AAATATGTTAAAATTACTAAATAATATGAAAACCACATTATACTTGTAATTTTCAGACACTTTTCTCCTACCTTAAGATTTTAACATCTT GTAAATATTAATATTTGAAGGGGAGAGGAAAAATACATTTGTAGTAGAAATATTCCCTCTAACAATTCTGTTTAACTAGTAAGTTTTTTT TAAGTTATCTTCCATGCCTGCTTCCCTAGTCTGAACTCCACATTCCAGTTGTCAGAAGAATGAATGGATTTAAATTTTCTAATCATTATT TTGGGCCCATGTTAGCAGTTGAAACAATTAAGTTCCTCACTCTTTCCTGCTTTTAGGATGATTTTAGACTGTGAGCATAAAATCAACCCT TTCTGTCAGCACAGAATTGAACATCGAATGGAGCAAGGTCTACACTCTCAGCCTGTAGCTGTGCTAATGTTAGGATTGAATTGTTCTATT AATTCCCTCAAGAGACCCACAGCCTCAAAAGAGTTGCTTATTATCAGATGTCCGAAATTCAGAAACCCAAAGTCAGGCAAAGAAGGAAAC TGAGATAATGATTTAATTTTTTTAAGTCACTGCAGGATTTCTCTCAAAGAAAACATCTGAAAATGGTTGAGAAAGTAGTTCCAGATCATT AACTATTTTACAGAGGGACTGAAAGCCAGGGAAAATAAAGAACAGAATGATAGTAGTATCTTGATATTAAATTTGCATCAGAAATGAGCA AAATATGTCAATATGAAATAATTTGAAATCAAATTCAGATTCACATGTATAGTGCATAGTTCAAGAAATAATGCTTACTCTTGTAAAAAA AAAAAATATATATATATGTATCAGCAGGTAGAGTGTGGGAGCTCCAACTTTGTTGTGAAAGCTGATAACAGAGTATGATTCTTTCCAGTT ACAAAATACTGTATTACTTTAGTTATAGCAAGCAGTACATAAATGACATCAACAACTCAGGCTGCTCCCTGACATAAAAGCCAGTTCCAT CTTTACTGCAGATGACAGGAGACTTTCCAAGACCTGCAGAGGCCCCCTCCACCCCAACCTTAGTGCATGCTCACACACACACACACACAC ACACACACACACACACACACACACATTTTTGGCTTTTGACCCACTCTGTGTGTTCCACTGAAGTTATCTTTTCCTTAATAGATTCACACA GAATTACCCCATCCTGCAAAATCCTTATCCCTATGAATCTCTAAAATATATTAAATAATGTGTTATATATTTGCTTTTTGTAAATCTTTA TTTAATTAATTTATATATACTTTGTGAAGTCTTATACTGTACATCATAAAGCGATGTCATCTGTAGTTGGTTCAATATAATGTTTATGAT CATTTTGATAAGAAATAACTTTGGACATTAGGCCCTTGTTAAGAAATAAAACACCCATTATAAATTTGCTTCTGTTGGAAAATACATGAT TTGGCATACTTCATTTTTAGTAACAATCTATTCTAGATAAATGATAATTTGGGGACATCTGTACTTAAAAACTAGCTGAACTACGTTTTG GGATGAGATGCAAAGCAACAGCTGTCCCTGGAACTGAAATGTGAATTTCTAGCAGAACAGAAAATATTATAATAATGAGGCAATAATAAA ATTAGGAAATTAAATTATTTTTAAATCTGTCTGTGTGATTTTTCCCCTTGGTAAAAATACATGAAATACATAATTGAAAAATTACCTTCT TCTGAAGTCGTAGTTTTTAATCTTAACCATCAATAAATAAACCTATTGTTAACAATGTCTTATTCATAATTCTAAAAAATTTACAAATGA TATTGCTATGAGGTTGTGCACTATTAAAGTTTGCTCCATCACTTAAAGGTAAAGCAGTTCAAAAATACTACTTTACATCACAACTTTGCA TGGCTGAGATTTTGAACAACTAAATTGATGGTTTTACCCACAAGTTATTTCATAAAGCTAACACTGTAATATTACTTGGTTTTCTTATAC TTTTGTTATCATGTGATGAAATGTAACTATGTAATTAAACAAAATTCTGACAATCATATTCTGCTAATGTTTAAAATGTTACTTATTCCT >78600_78600_3_RTTN-DOK6_RTTN_chr18_67833298_ENST00000454359_DOK6_chr18_67424992_ENST00000382713_length(amino acids)=728AA_BP=638 MVLAGLIRKLGHQLAEIRERALKSILCKIEHNLICYADLIQERQLFLHLLEWFNFPSVPMKEEVLNLLSRLVKYPPAVQHLVDVGAVEFL SKLRSNVEPNLQAEIDGILDGLFLLPSEVPALSSASYQTNQTELSKNPEILTGYFPQDKSNFQQMEVPPRPVVNQTVKCLKFSTFPWLPL TTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDFPAEIFLQRPKIVQSLLSLLKLAFGDGKHRLALQSVSCLQQLCMYLRNRLNFH RDPGFFSNKHDTVSQNSSLSYCHEARGTHHSQNPSPGSSSPRPSVVGRTGQRPRGDGQDWDAASSSGSSSHAHVNSRISVHSPLDMGHID LPELETEDTLELQFQQLSLPQFCVSILESAVPLLRTGSRQVIIRVLELLTEDMTLIGEAISTDIWDDSSLFGIDMKEKLLLVLGALGETM CYHKSSISLEQPEVMLVHHRMAFISISLFAVRLLQTLLPVEKASEFLSEPMSTALFLLSLDMPISLEYPNIHEAVVAYLEQLNSENYSIY KRTAEAVYSIECTCNFLSDIGKEGEKNLLELVELADQALRSFSYHQHFPLIKEIISICSKIWKSAQASPLLQGESQKVLLHMLSHPLPRV KAETYHCCLEITKLQTSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQTFPSYAPEQSEEAQQPLSRSSSYGF -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for RTTN-DOK6 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for RTTN-DOK6 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for RTTN-DOK6 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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