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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SAE1-SLC9A1 (FusionGDB2 ID:79017)

Fusion Gene Summary for SAE1-SLC9A1

check button Fusion gene summary
Fusion gene informationFusion gene name: SAE1-SLC9A1
Fusion gene ID: 79017
HgeneTgene
Gene symbol

SAE1

SLC9A1

Gene ID

10055

6548

Gene nameSUMO1 activating enzyme subunit 1solute carrier family 9 member A1
SynonymsAOS1|HSPC140|SUA1|UBLE1AAPNH|LIKNS|NHE-1|NHE1|PPP1R143
Cytomap

19q13.32

1p36.11

Type of geneprotein-codingprotein-coding
DescriptionSUMO-activating enzyme subunit 1SUMO-1 activating enzyme E1 N subunitSUMO-1 activating enzyme subunit 1activator of SUMO1sentrin/SUMO-activating protein AOS1ubiquitin-like 1-activating enzyme E1Aubiquitin-like protein SUMO-1 activating enzymesodium/hydrogen exchanger 1Na(+)/H(+) exchanger 1Na-Li countertransporterprotein phosphatase 1, regulatory subunit 143solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive)solute carrier family 9 (sod
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000270225, ENST00000392776, 
ENST00000413379, ENST00000598840, 
ENST00000540850, 		ENST00000374086, 
ENST00000490329, ENST00000545949, 
ENST00000263980, 
Fusion gene scores* DoF score17 X 10 X 12=20409 X 7 X 7=441
# samples 1911
** MAII scorelog2(19/2040*10)=-3.42449782852791
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/441*10)=-2.00327513203286
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SAE1 [Title/Abstract] AND SLC9A1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSAE1(47646862)-SLC9A1(27429803), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSAE1

GO:0016925

protein sumoylation

15660128|20164921

HgeneSAE1

GO:0033235

positive regulation of protein sumoylation

10187858

TgeneSLC9A1

GO:0006883

cellular sodium ion homeostasis

24840010

TgeneSLC9A1

GO:0006885

regulation of pH

8901634

TgeneSLC9A1

GO:0010447

response to acidic pH

8901634

TgeneSLC9A1

GO:0045944

positive regulation of transcription by RNA polymerase II

22688515

TgeneSLC9A1

GO:0051453

regulation of intracellular pH

15035633|24840010

TgeneSLC9A1

GO:0070886

positive regulation of calcineurin-NFAT signaling cascade

22688515

TgeneSLC9A1

GO:0071468

cellular response to acidic pH

24840010

TgeneSLC9A1

GO:0098719

sodium ion import across plasma membrane

24840010

TgeneSLC9A1

GO:1902600

proton transmembrane transport

24840010


check buttonFusion gene breakpoints across SAE1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC9A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCSTCGA-N9-A4Q8SAE1chr19

47646862

+SLC9A1chr1

27429803

-


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Fusion Gene ORF analysis for SAE1-SLC9A1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000270225ENST00000374086SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5CDS-intronENST00000270225ENST00000490329SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5CDS-intronENST00000270225ENST00000545949SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5CDS-intronENST00000392776ENST00000374086SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5CDS-intronENST00000392776ENST00000490329SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5CDS-intronENST00000392776ENST00000545949SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5CDS-intronENST00000413379ENST00000374086SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5CDS-intronENST00000413379ENST00000490329SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5CDS-intronENST00000413379ENST00000545949SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5CDS-intronENST00000598840ENST00000374086SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5CDS-intronENST00000598840ENST00000490329SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5CDS-intronENST00000598840ENST00000545949SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5UTR-3CDSENST00000540850ENST00000263980SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5UTR-intronENST00000540850ENST00000374086SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5UTR-intronENST00000540850ENST00000490329SAE1chr19

47646862

+SLC9A1chr1

27429803

-
5UTR-intronENST00000540850ENST00000545949SAE1chr19

47646862

+SLC9A1chr1

27429803

-
In-frameENST00000270225ENST00000263980SAE1chr19

47646862

+SLC9A1chr1

27429803

-
In-frameENST00000392776ENST00000263980SAE1chr19

47646862

+SLC9A1chr1

27429803

-
In-frameENST00000413379ENST00000263980SAE1chr19

47646862

+SLC9A1chr1

27429803

-
In-frameENST00000598840ENST00000263980SAE1chr19

47646862

+SLC9A1chr1

27429803

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000413379SAE1chr1947646862+ENST00000263980SLC9A1chr127429803-2767312181274418
ENST00000598840SAE1chr1947646862+ENST00000263980SLC9A1chr127429803-275830391265418
ENST00000270225SAE1chr1947646862+ENST00000263980SLC9A1chr127429803-2733278291240403
ENST00000392776SAE1chr1947646862+ENST00000263980SLC9A1chr127429803-2701246361208390

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000413379ENST00000263980SAE1chr1947646862+SLC9A1chr127429803-0.0043832650.9956168
ENST00000598840ENST00000263980SAE1chr1947646862+SLC9A1chr127429803-0.0043220610.995678
ENST00000270225ENST00000263980SAE1chr1947646862+SLC9A1chr127429803-0.0043508640.99564916
ENST00000392776ENST00000263980SAE1chr1947646862+SLC9A1chr127429803-0.0047230220.9952769

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Fusion Genomic Features for SAE1-SLC9A1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SAE1-SLC9A1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:47646862/chr1:27429803)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605382_4020556.0IntramembraneName%3DH10
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412500_815495816.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605128_1290556.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605150_1540556.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605175_1910556.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000374086051_120556.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605212_2270556.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605248_2560556.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605277_2940556.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605316_3380556.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST000003740860534_1050556.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605359_3810556.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605403_4100556.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605431_4480556.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605471_4790556.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605500_8150556.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605106_1270556.0TransmembraneHelical%3B Name%3DM2
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605130_1490556.0TransmembraneHelical%3B Name%3DM3
TgeneSLC9A1chr19:47646862chr1:27429803ENST000003740860513_330556.0TransmembraneHelical%3B Name%3DM1
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605155_1740556.0TransmembraneHelical%3B Name%3DM4
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605192_2110556.0TransmembraneHelical%3B Name%3DM5
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605228_2470556.0TransmembraneHelical%3B Name%3DM6
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605257_2760556.0TransmembraneHelical%3B Name%3DM7
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605295_3150556.0TransmembraneHelical%3B Name%3DM8
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605339_3580556.0TransmembraneHelical%3B Name%3DM9
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605411_4300556.0TransmembraneHelical%3B Name%3DM10
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605449_4700556.0TransmembraneHelical%3B Name%3DM11
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605480_4990556.0TransmembraneHelical%3B Name%3DM12

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412382_402495816.0IntramembraneName%3DH10
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412128_129495816.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412150_154495816.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412175_191495816.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST000002639804121_12495816.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412212_227495816.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412248_256495816.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412277_294495816.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412316_338495816.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000026398041234_105495816.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412359_381495816.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412403_410495816.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412431_448495816.0Topological domainCytoplasmic
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412471_479495816.0Topological domainExtracellular
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412106_127495816.0TransmembraneHelical%3B Name%3DM2
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412130_149495816.0TransmembraneHelical%3B Name%3DM3
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000026398041213_33495816.0TransmembraneHelical%3B Name%3DM1
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412155_174495816.0TransmembraneHelical%3B Name%3DM4
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412192_211495816.0TransmembraneHelical%3B Name%3DM5
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412228_247495816.0TransmembraneHelical%3B Name%3DM6
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412257_276495816.0TransmembraneHelical%3B Name%3DM7
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412295_315495816.0TransmembraneHelical%3B Name%3DM8
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412339_358495816.0TransmembraneHelical%3B Name%3DM9
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412411_430495816.0TransmembraneHelical%3B Name%3DM10
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412449_470495816.0TransmembraneHelical%3B Name%3DM11
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412480_499495816.0TransmembraneHelical%3B Name%3DM12


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Fusion Gene Sequence for SAE1-SLC9A1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>79017_79017_1_SAE1-SLC9A1_SAE1_chr19_47646862_ENST00000270225_SLC9A1_chr1_27429803_ENST00000263980_length(transcript)=2733nt_BP=278nt
GTGGCGCGCGGGTCCGGCGGGCGGTTGGCTTGAGCGGGACCGGAGCTGAGGCAGGAAGAGCCGGCGCCATGGTGGAGAAGGAGGAGGCTG
GCGGCGGCATTAGCGAGGAGGAGGCGGCACAGTATGACCGGCAGATCCGCCTGTGGGGACTGGAGGCCCAGAAACGGCTGCGGGCCTCTC
GGGTGCTTCTTGTCGGCTTGAAAGGACTTGGGGCTGAAATTGCCAAGAATCTCATCTTGGCAGGAGTGAAAGGACTGACCATGCTGGATC
ACGAACAGGGCATGACCATTCGGCCCCTGGTAGACCTGTTGGCTGTGAAGAAAAAGCAAGAGACGAAGCGCTCCATCAACGAAGAGATCC
ACACACAGTTCCTGGACCACCTTCTGACAGGCATCGAAGACATCTGTGGCCACTACGGTCACCACCACTGGAAGGACAAGCTCAACCGGT
TTAATAAGAAATATGTGAAGAAGTGTCTGATAGCTGGCGAGCGCTCCAAGGAGCCCCAGCTCATTGCCTTCTACCACAAGATGGAGATGA
AGCAGGCCATCGAGCTGGTGGAGAGCGGGGGCATGGGCAAGATCCCCTCTGCCGTCTCCACCGTCTCCATGCAGAACATCCACCCCAAGT
CCCTGCCTTCCGAGCGCATCCTGCCAGCACTGTCCAAGGACAAGGAGGAGGAGATCCGCAAAATCCTGAGGAACAACTTGCAGAAGACCA
GGCAGCGGCTGCGGTCCTACAACAGACACACGCTGGTGGCAGACCCCTACGAGGAAGCCTGGAACCAGATGCTGCTCCGGAGGCAGAAGG
CCCGGCAGCTGGAGCAGAAGATCAACAACTACCTGACGGTGCCAGCCCACAAGCTGGACTCACCCACCATGTCTCGGGCCCGCATCGGCT
CAGACCCACTGGCCTATGAGCCGAAGGAGGACCTGCCTGTCATCACCATCGACCCGGCTTCCCCGCAGTCACCCGAGTCTGTGGACCTGG
TGAATGAAGAGCTGAAGGGCAAAGTCTTAGGGTTGAGCCGGGATCCTGCAAAGGTGGCTGAGGAGGACGAGGACGACGATGGGGGCATCA
TGATGCGGAGCAAGGAGACTTCGTCCCCAGGAACCGACGATGTCTTCACCCCCGCGCCCAGTGACAGCCCCAGCTCCCAGAGGATACAGC
GCTGCCTCAGTGACCCAGGCCCACACCCTGAGCCTGGGGAGGGAGAACCGTTCTTCCCCAAGGGGCAGTAACACCAGGGCCAGCAGGCAG
CGCCTGTCCCCTCACAGACTCTTCCACCAGAGCAGGGGCTGCTGGGGGCTCCCCTTGCCCTTCCTGACCCGGATTGGCCCTGCCCCTCCC
CCTACCGCATGGCAGCTGGGCCCACAGCCCCCACCCCAGCACAGCTCCTCCCCTGCCGCCTCCCGGGAAGCATCCTCCCCACCAGAGCTG
CCTCCCCAATCCATTTGGCAGAACTGCTGGGGCTGGTGAGGCCGGCCCTGCCCCTCCCTAGATCCAGGCTTCTCCCGGACCTGGACTAGG
GCCTCGGAGGCTCCTCCCTCTGCCTCATCCTCCTCCTCATTCAGACCAATCTTAGTTTCTAACCAAAGAGTCTCTGGCTCAGCTGTGGTC
CCACCCAGGAAGGGAGGGAGCTGAGGCCTCCCTTGAGTAGGCCCTGCTTTATCAGGGGACAAACCAGGGGTACCAGGCACATGGCTGGGG
GAGGGACTGCTGACCCACCAAGGTCTCACACTCCTCCTGCCAGCTCTGTCACCCTGGCCACCACCCAACCTGTCCTTACTCAGAGCTGCG
GGCTGAGGGCATCTCTGAGTGTCTCTGCCTGGAGCAGGGGTGGTTTCTACGGTGACAGTGACGTGACTCAGAGCTTTTCGAACTGTGCTC
CCACGGGGACCACTGGGCCCCTCAGGGGAAGCTGCTAGGGGAAGGACTGGCCGTGGCTCCAGAATGTGCTGCCTTTTTAAGTTTTGTTTG
TTCACACTCCTATATATGATTGTTTGCACAGAGGGCGCTCCTGTTTTTAAAACATTTTGAAAACCCCTGGCTGAACAGTGCTCTGCCTCT
AACTCCCTCCTCACACTCCAGAATTACCCTTCCTCATCTGTGCCTGTCTGTCCAACCCCTCCCCCACGTCTCTCTGCCTGCTGGGCTCTT
AACTGTTGCTCGAAGACTGTGACATCAGAAGTAACTCCCACTCCTAATCAAGAGTCTCTCCAGCCTCACAGATGCTGGCCTCTTGGCACC
TGCCTAGCTCTTGGGCCTGACCTCCAGTCCTGCTGGCCTGCTCTTACTTCCCCCACCCTGGGTTTGGCCCCTGGAACCTTTCCCTTGTGT
GTACCACACCCTGCCTGCTGTGGAGCCCATTGTGGAGGCGGTGGGGGGGAGAAGGCCTCCCCTGAGGATCCCCTGTCCCCTGGGGCTGGT
GGATTGGGCAGAATCCTGGGCCCCCAGAGACCTTTGCCCACACACACTCCTTCCCCTTGTCCCTGGGGCACTCCCCCAGGATTGTGCAAT
AGTCAGAGTGTCCCTTTTTGCAGGGGACTGGGCCATGGGTCCTCGGCCCATCTGTCCATCCTCCTCTCCATGCAAGTGCTGTTTGGGCAG
GAGTCACCATGCAAGGGTGACATCGACAACCACGTACCAAGCCACCGCAGCTGCTGCCACTCTGCTGCCTGTACAGAAGAAACTGAATCT

>79017_79017_1_SAE1-SLC9A1_SAE1_chr19_47646862_ENST00000270225_SLC9A1_chr1_27429803_ENST00000263980_length(amino acids)=403AA_BP=82
MSGTGAEAGRAGAMVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQGMTIRPL
VDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESG
GMGKIPSAVSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINN
YLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSP

--------------------------------------------------------------
>79017_79017_2_SAE1-SLC9A1_SAE1_chr19_47646862_ENST00000392776_SLC9A1_chr1_27429803_ENST00000263980_length(transcript)=2701nt_BP=246nt
AGCGGGACCGGAGCTGAGGCAGGAAGAGCCGGCGCCATGGTGGAGAAGGAGGAGGCTGGCGGCGGCATTAGCGAGGAGGAGGCGGCACAG
TATGACCGGCAGATCCGCCTGTGGGGACTGGAGGCCCAGAAACGGCTGCGGGCCTCTCGGGTGCTTCTTGTCGGCTTGAAAGGACTTGGG
GCTGAAATTGCCAAGAATCTCATCTTGGCAGGAGTGAAAGGACTGACCATGCTGGATCACGAACAGGGCATGACCATTCGGCCCCTGGTA
GACCTGTTGGCTGTGAAGAAAAAGCAAGAGACGAAGCGCTCCATCAACGAAGAGATCCACACACAGTTCCTGGACCACCTTCTGACAGGC
ATCGAAGACATCTGTGGCCACTACGGTCACCACCACTGGAAGGACAAGCTCAACCGGTTTAATAAGAAATATGTGAAGAAGTGTCTGATA
GCTGGCGAGCGCTCCAAGGAGCCCCAGCTCATTGCCTTCTACCACAAGATGGAGATGAAGCAGGCCATCGAGCTGGTGGAGAGCGGGGGC
ATGGGCAAGATCCCCTCTGCCGTCTCCACCGTCTCCATGCAGAACATCCACCCCAAGTCCCTGCCTTCCGAGCGCATCCTGCCAGCACTG
TCCAAGGACAAGGAGGAGGAGATCCGCAAAATCCTGAGGAACAACTTGCAGAAGACCAGGCAGCGGCTGCGGTCCTACAACAGACACACG
CTGGTGGCAGACCCCTACGAGGAAGCCTGGAACCAGATGCTGCTCCGGAGGCAGAAGGCCCGGCAGCTGGAGCAGAAGATCAACAACTAC
CTGACGGTGCCAGCCCACAAGCTGGACTCACCCACCATGTCTCGGGCCCGCATCGGCTCAGACCCACTGGCCTATGAGCCGAAGGAGGAC
CTGCCTGTCATCACCATCGACCCGGCTTCCCCGCAGTCACCCGAGTCTGTGGACCTGGTGAATGAAGAGCTGAAGGGCAAAGTCTTAGGG
TTGAGCCGGGATCCTGCAAAGGTGGCTGAGGAGGACGAGGACGACGATGGGGGCATCATGATGCGGAGCAAGGAGACTTCGTCCCCAGGA
ACCGACGATGTCTTCACCCCCGCGCCCAGTGACAGCCCCAGCTCCCAGAGGATACAGCGCTGCCTCAGTGACCCAGGCCCACACCCTGAG
CCTGGGGAGGGAGAACCGTTCTTCCCCAAGGGGCAGTAACACCAGGGCCAGCAGGCAGCGCCTGTCCCCTCACAGACTCTTCCACCAGAG
CAGGGGCTGCTGGGGGCTCCCCTTGCCCTTCCTGACCCGGATTGGCCCTGCCCCTCCCCCTACCGCATGGCAGCTGGGCCCACAGCCCCC
ACCCCAGCACAGCTCCTCCCCTGCCGCCTCCCGGGAAGCATCCTCCCCACCAGAGCTGCCTCCCCAATCCATTTGGCAGAACTGCTGGGG
CTGGTGAGGCCGGCCCTGCCCCTCCCTAGATCCAGGCTTCTCCCGGACCTGGACTAGGGCCTCGGAGGCTCCTCCCTCTGCCTCATCCTC
CTCCTCATTCAGACCAATCTTAGTTTCTAACCAAAGAGTCTCTGGCTCAGCTGTGGTCCCACCCAGGAAGGGAGGGAGCTGAGGCCTCCC
TTGAGTAGGCCCTGCTTTATCAGGGGACAAACCAGGGGTACCAGGCACATGGCTGGGGGAGGGACTGCTGACCCACCAAGGTCTCACACT
CCTCCTGCCAGCTCTGTCACCCTGGCCACCACCCAACCTGTCCTTACTCAGAGCTGCGGGCTGAGGGCATCTCTGAGTGTCTCTGCCTGG
AGCAGGGGTGGTTTCTACGGTGACAGTGACGTGACTCAGAGCTTTTCGAACTGTGCTCCCACGGGGACCACTGGGCCCCTCAGGGGAAGC
TGCTAGGGGAAGGACTGGCCGTGGCTCCAGAATGTGCTGCCTTTTTAAGTTTTGTTTGTTCACACTCCTATATATGATTGTTTGCACAGA
GGGCGCTCCTGTTTTTAAAACATTTTGAAAACCCCTGGCTGAACAGTGCTCTGCCTCTAACTCCCTCCTCACACTCCAGAATTACCCTTC
CTCATCTGTGCCTGTCTGTCCAACCCCTCCCCCACGTCTCTCTGCCTGCTGGGCTCTTAACTGTTGCTCGAAGACTGTGACATCAGAAGT
AACTCCCACTCCTAATCAAGAGTCTCTCCAGCCTCACAGATGCTGGCCTCTTGGCACCTGCCTAGCTCTTGGGCCTGACCTCCAGTCCTG
CTGGCCTGCTCTTACTTCCCCCACCCTGGGTTTGGCCCCTGGAACCTTTCCCTTGTGTGTACCACACCCTGCCTGCTGTGGAGCCCATTG
TGGAGGCGGTGGGGGGGAGAAGGCCTCCCCTGAGGATCCCCTGTCCCCTGGGGCTGGTGGATTGGGCAGAATCCTGGGCCCCCAGAGACC
TTTGCCCACACACACTCCTTCCCCTTGTCCCTGGGGCACTCCCCCAGGATTGTGCAATAGTCAGAGTGTCCCTTTTTGCAGGGGACTGGG
CCATGGGTCCTCGGCCCATCTGTCCATCCTCCTCTCCATGCAAGTGCTGTTTGGGCAGGAGTCACCATGCAAGGGTGACATCGACAACCA
CGTACCAAGCCACCGCAGCTGCTGCCACTCTGCTGCCTGTACAGAAGAAACTGAATCTTTTTCATATTCTAATAAATCAATGTGAGTTTT

>79017_79017_2_SAE1-SLC9A1_SAE1_chr19_47646862_ENST00000392776_SLC9A1_chr1_27429803_ENST00000263980_length(amino acids)=390AA_BP=69
MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQGMTIRPLVDLLAVKKKQETK
RSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVS
MQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPT
MSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTPAPSDS

--------------------------------------------------------------
>79017_79017_3_SAE1-SLC9A1_SAE1_chr19_47646862_ENST00000413379_SLC9A1_chr1_27429803_ENST00000263980_length(transcript)=2767nt_BP=312nt
AGAAGCACTCCGGGCGTGCTGCCGGCGGCGGTAGGTGGCGCGCGGGTCCGGCGGGCGGTTGGCTTGAGCGGGACCGGAGCTGAGGCAGGA
AGAGCCGGCGCCATGGTGGAGAAGGAGGAGGCTGGCGGCGGCATTAGCGAGGAGGAGGCGGCACAGTATGACCGGCAGATCCGCCTGTGG
GGACTGGAGGCCCAGAAACGGCTGCGGGCCTCTCGGGTGCTTCTTGTCGGCTTGAAAGGACTTGGGGCTGAAATTGCCAAGAATCTCATC
TTGGCAGGAGTGAAAGGACTGACCATGCTGGATCACGAACAGGGCATGACCATTCGGCCCCTGGTAGACCTGTTGGCTGTGAAGAAAAAG
CAAGAGACGAAGCGCTCCATCAACGAAGAGATCCACACACAGTTCCTGGACCACCTTCTGACAGGCATCGAAGACATCTGTGGCCACTAC
GGTCACCACCACTGGAAGGACAAGCTCAACCGGTTTAATAAGAAATATGTGAAGAAGTGTCTGATAGCTGGCGAGCGCTCCAAGGAGCCC
CAGCTCATTGCCTTCTACCACAAGATGGAGATGAAGCAGGCCATCGAGCTGGTGGAGAGCGGGGGCATGGGCAAGATCCCCTCTGCCGTC
TCCACCGTCTCCATGCAGAACATCCACCCCAAGTCCCTGCCTTCCGAGCGCATCCTGCCAGCACTGTCCAAGGACAAGGAGGAGGAGATC
CGCAAAATCCTGAGGAACAACTTGCAGAAGACCAGGCAGCGGCTGCGGTCCTACAACAGACACACGCTGGTGGCAGACCCCTACGAGGAA
GCCTGGAACCAGATGCTGCTCCGGAGGCAGAAGGCCCGGCAGCTGGAGCAGAAGATCAACAACTACCTGACGGTGCCAGCCCACAAGCTG
GACTCACCCACCATGTCTCGGGCCCGCATCGGCTCAGACCCACTGGCCTATGAGCCGAAGGAGGACCTGCCTGTCATCACCATCGACCCG
GCTTCCCCGCAGTCACCCGAGTCTGTGGACCTGGTGAATGAAGAGCTGAAGGGCAAAGTCTTAGGGTTGAGCCGGGATCCTGCAAAGGTG
GCTGAGGAGGACGAGGACGACGATGGGGGCATCATGATGCGGAGCAAGGAGACTTCGTCCCCAGGAACCGACGATGTCTTCACCCCCGCG
CCCAGTGACAGCCCCAGCTCCCAGAGGATACAGCGCTGCCTCAGTGACCCAGGCCCACACCCTGAGCCTGGGGAGGGAGAACCGTTCTTC
CCCAAGGGGCAGTAACACCAGGGCCAGCAGGCAGCGCCTGTCCCCTCACAGACTCTTCCACCAGAGCAGGGGCTGCTGGGGGCTCCCCTT
GCCCTTCCTGACCCGGATTGGCCCTGCCCCTCCCCCTACCGCATGGCAGCTGGGCCCACAGCCCCCACCCCAGCACAGCTCCTCCCCTGC
CGCCTCCCGGGAAGCATCCTCCCCACCAGAGCTGCCTCCCCAATCCATTTGGCAGAACTGCTGGGGCTGGTGAGGCCGGCCCTGCCCCTC
CCTAGATCCAGGCTTCTCCCGGACCTGGACTAGGGCCTCGGAGGCTCCTCCCTCTGCCTCATCCTCCTCCTCATTCAGACCAATCTTAGT
TTCTAACCAAAGAGTCTCTGGCTCAGCTGTGGTCCCACCCAGGAAGGGAGGGAGCTGAGGCCTCCCTTGAGTAGGCCCTGCTTTATCAGG
GGACAAACCAGGGGTACCAGGCACATGGCTGGGGGAGGGACTGCTGACCCACCAAGGTCTCACACTCCTCCTGCCAGCTCTGTCACCCTG
GCCACCACCCAACCTGTCCTTACTCAGAGCTGCGGGCTGAGGGCATCTCTGAGTGTCTCTGCCTGGAGCAGGGGTGGTTTCTACGGTGAC
AGTGACGTGACTCAGAGCTTTTCGAACTGTGCTCCCACGGGGACCACTGGGCCCCTCAGGGGAAGCTGCTAGGGGAAGGACTGGCCGTGG
CTCCAGAATGTGCTGCCTTTTTAAGTTTTGTTTGTTCACACTCCTATATATGATTGTTTGCACAGAGGGCGCTCCTGTTTTTAAAACATT
TTGAAAACCCCTGGCTGAACAGTGCTCTGCCTCTAACTCCCTCCTCACACTCCAGAATTACCCTTCCTCATCTGTGCCTGTCTGTCCAAC
CCCTCCCCCACGTCTCTCTGCCTGCTGGGCTCTTAACTGTTGCTCGAAGACTGTGACATCAGAAGTAACTCCCACTCCTAATCAAGAGTC
TCTCCAGCCTCACAGATGCTGGCCTCTTGGCACCTGCCTAGCTCTTGGGCCTGACCTCCAGTCCTGCTGGCCTGCTCTTACTTCCCCCAC
CCTGGGTTTGGCCCCTGGAACCTTTCCCTTGTGTGTACCACACCCTGCCTGCTGTGGAGCCCATTGTGGAGGCGGTGGGGGGGAGAAGGC
CTCCCCTGAGGATCCCCTGTCCCCTGGGGCTGGTGGATTGGGCAGAATCCTGGGCCCCCAGAGACCTTTGCCCACACACACTCCTTCCCC
TTGTCCCTGGGGCACTCCCCCAGGATTGTGCAATAGTCAGAGTGTCCCTTTTTGCAGGGGACTGGGCCATGGGTCCTCGGCCCATCTGTC
CATCCTCCTCTCCATGCAAGTGCTGTTTGGGCAGGAGTCACCATGCAAGGGTGACATCGACAACCACGTACCAAGCCACCGCAGCTGCTG

>79017_79017_3_SAE1-SLC9A1_SAE1_chr19_47646862_ENST00000413379_SLC9A1_chr1_27429803_ENST00000263980_length(amino acids)=418AA_BP=97
MPAAVGGARVRRAVGLSGTGAEAGRAGAMVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKG
LTMLDHEQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFY
HKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQML
LRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDED

--------------------------------------------------------------
>79017_79017_4_SAE1-SLC9A1_SAE1_chr19_47646862_ENST00000598840_SLC9A1_chr1_27429803_ENST00000263980_length(transcript)=2758nt_BP=303nt
CCGGGCGTGCTGCCGGCGGCGGTAGGTGGCGCGCGGGTCCGGCGGGCGGTTGGCTTGAGCGGGACCGGAGCTGAGGCAGGAAGAGCCGGC
GCCATGGTGGAGAAGGAGGAGGCTGGCGGCGGCATTAGCGAGGAGGAGGCGGCACAGTATGACCGGCAGATCCGCCTGTGGGGACTGGAG
GCCCAGAAACGGCTGCGGGCCTCTCGGGTGCTTCTTGTCGGCTTGAAAGGACTTGGGGCTGAAATTGCCAAGAATCTCATCTTGGCAGGA
GTGAAAGGACTGACCATGCTGGATCACGAACAGGGCATGACCATTCGGCCCCTGGTAGACCTGTTGGCTGTGAAGAAAAAGCAAGAGACG
AAGCGCTCCATCAACGAAGAGATCCACACACAGTTCCTGGACCACCTTCTGACAGGCATCGAAGACATCTGTGGCCACTACGGTCACCAC
CACTGGAAGGACAAGCTCAACCGGTTTAATAAGAAATATGTGAAGAAGTGTCTGATAGCTGGCGAGCGCTCCAAGGAGCCCCAGCTCATT
GCCTTCTACCACAAGATGGAGATGAAGCAGGCCATCGAGCTGGTGGAGAGCGGGGGCATGGGCAAGATCCCCTCTGCCGTCTCCACCGTC
TCCATGCAGAACATCCACCCCAAGTCCCTGCCTTCCGAGCGCATCCTGCCAGCACTGTCCAAGGACAAGGAGGAGGAGATCCGCAAAATC
CTGAGGAACAACTTGCAGAAGACCAGGCAGCGGCTGCGGTCCTACAACAGACACACGCTGGTGGCAGACCCCTACGAGGAAGCCTGGAAC
CAGATGCTGCTCCGGAGGCAGAAGGCCCGGCAGCTGGAGCAGAAGATCAACAACTACCTGACGGTGCCAGCCCACAAGCTGGACTCACCC
ACCATGTCTCGGGCCCGCATCGGCTCAGACCCACTGGCCTATGAGCCGAAGGAGGACCTGCCTGTCATCACCATCGACCCGGCTTCCCCG
CAGTCACCCGAGTCTGTGGACCTGGTGAATGAAGAGCTGAAGGGCAAAGTCTTAGGGTTGAGCCGGGATCCTGCAAAGGTGGCTGAGGAG
GACGAGGACGACGATGGGGGCATCATGATGCGGAGCAAGGAGACTTCGTCCCCAGGAACCGACGATGTCTTCACCCCCGCGCCCAGTGAC
AGCCCCAGCTCCCAGAGGATACAGCGCTGCCTCAGTGACCCAGGCCCACACCCTGAGCCTGGGGAGGGAGAACCGTTCTTCCCCAAGGGG
CAGTAACACCAGGGCCAGCAGGCAGCGCCTGTCCCCTCACAGACTCTTCCACCAGAGCAGGGGCTGCTGGGGGCTCCCCTTGCCCTTCCT
GACCCGGATTGGCCCTGCCCCTCCCCCTACCGCATGGCAGCTGGGCCCACAGCCCCCACCCCAGCACAGCTCCTCCCCTGCCGCCTCCCG
GGAAGCATCCTCCCCACCAGAGCTGCCTCCCCAATCCATTTGGCAGAACTGCTGGGGCTGGTGAGGCCGGCCCTGCCCCTCCCTAGATCC
AGGCTTCTCCCGGACCTGGACTAGGGCCTCGGAGGCTCCTCCCTCTGCCTCATCCTCCTCCTCATTCAGACCAATCTTAGTTTCTAACCA
AAGAGTCTCTGGCTCAGCTGTGGTCCCACCCAGGAAGGGAGGGAGCTGAGGCCTCCCTTGAGTAGGCCCTGCTTTATCAGGGGACAAACC
AGGGGTACCAGGCACATGGCTGGGGGAGGGACTGCTGACCCACCAAGGTCTCACACTCCTCCTGCCAGCTCTGTCACCCTGGCCACCACC
CAACCTGTCCTTACTCAGAGCTGCGGGCTGAGGGCATCTCTGAGTGTCTCTGCCTGGAGCAGGGGTGGTTTCTACGGTGACAGTGACGTG
ACTCAGAGCTTTTCGAACTGTGCTCCCACGGGGACCACTGGGCCCCTCAGGGGAAGCTGCTAGGGGAAGGACTGGCCGTGGCTCCAGAAT
GTGCTGCCTTTTTAAGTTTTGTTTGTTCACACTCCTATATATGATTGTTTGCACAGAGGGCGCTCCTGTTTTTAAAACATTTTGAAAACC
CCTGGCTGAACAGTGCTCTGCCTCTAACTCCCTCCTCACACTCCAGAATTACCCTTCCTCATCTGTGCCTGTCTGTCCAACCCCTCCCCC
ACGTCTCTCTGCCTGCTGGGCTCTTAACTGTTGCTCGAAGACTGTGACATCAGAAGTAACTCCCACTCCTAATCAAGAGTCTCTCCAGCC
TCACAGATGCTGGCCTCTTGGCACCTGCCTAGCTCTTGGGCCTGACCTCCAGTCCTGCTGGCCTGCTCTTACTTCCCCCACCCTGGGTTT
GGCCCCTGGAACCTTTCCCTTGTGTGTACCACACCCTGCCTGCTGTGGAGCCCATTGTGGAGGCGGTGGGGGGGAGAAGGCCTCCCCTGA
GGATCCCCTGTCCCCTGGGGCTGGTGGATTGGGCAGAATCCTGGGCCCCCAGAGACCTTTGCCCACACACACTCCTTCCCCTTGTCCCTG
GGGCACTCCCCCAGGATTGTGCAATAGTCAGAGTGTCCCTTTTTGCAGGGGACTGGGCCATGGGTCCTCGGCCCATCTGTCCATCCTCCT
CTCCATGCAAGTGCTGTTTGGGCAGGAGTCACCATGCAAGGGTGACATCGACAACCACGTACCAAGCCACCGCAGCTGCTGCCACTCTGC

>79017_79017_4_SAE1-SLC9A1_SAE1_chr19_47646862_ENST00000598840_SLC9A1_chr1_27429803_ENST00000263980_length(amino acids)=418AA_BP=97
MPAAVGGARVRRAVGLSGTGAEAGRAGAMVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKG
LTMLDHEQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFY
HKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQML
LRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDED

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SAE1-SLC9A1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412515_545495.0816.0CHP2
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605515_5450556.0CHP2
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412633_815495.0816.0TESC
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605633_8150556.0TESC
TgeneSLC9A1chr19:47646862chr1:27429803ENST00000263980412503_545495.0816.0TESC
TgeneSLC9A1chr19:47646862chr1:27429803ENST0000037408605503_5450556.0TESC


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SAE1-SLC9A1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SAE1-SLC9A1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource