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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ATP2C2-EIF3A (FusionGDB2 ID:7902)

Fusion Gene Summary for ATP2C2-EIF3A

check button Fusion gene summary
Fusion gene informationFusion gene name: ATP2C2-EIF3A
Fusion gene ID: 7902
HgeneTgene
Gene symbol

ATP2C2

EIF3A

Gene ID

9914

8661

Gene nameATPase secretory pathway Ca2+ transporting 2eukaryotic translation initiation factor 3 subunit A
SynonymsSPCA2EIF3|EIF3S10|P167|TIF32|eIF3-p170|eIF3-theta|p180|p185
Cytomap

16q24.1

10q26.11

Type of geneprotein-codingprotein-coding
Descriptioncalcium-transporting ATPase type 2C member 2ATPase 2C2ATPase, Ca++ transporting, type 2C, member 2secretory pathway Ca(2+)-ATPase 2secretory pathway calcium ATPase 2eukaryotic translation initiation factor 3 subunit AEIF3, p180 subunitcentrosomin homologcytoplasmic protein p167eIF-3-thetaeIF3 p167eIF3 p180eIF3 p185eukaryotic translation initiation factor 3 subunit 10eukaryotic translation initiation factor 3
Modification date2020032020200313
UniProtAcc

O75185

Q14152

Ensembl transtripts involved in fusion geneENST00000262429, ENST00000416219, 
ENST00000420010, 		ENST00000369144, 
ENST00000541549, 
Fusion gene scores* DoF score10 X 6 X 6=3608 X 9 X 3=216
# samples 129
** MAII scorelog2(12/360*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/216*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATP2C2 [Title/Abstract] AND EIF3A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATP2C2(84432115)-EIF3A(120817711), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneEIF3A

GO:0001732

formation of cytoplasmic translation initiation complex

17581632

TgeneEIF3A

GO:0075522

IRES-dependent viral translational initiation

9573242|23766293|24357634

TgeneEIF3A

GO:0075525

viral translational termination-reinitiation

21347434


check buttonFusion gene breakpoints across ATP2C2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EIF3A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABE841770ATP2C2chr16

84432115

-EIF3Achr10

120817711

+


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Fusion Gene ORF analysis for ATP2C2-EIF3A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000262429ENST00000369144ATP2C2chr16

84432115

-EIF3Achr10

120817711

+
In-frameENST00000262429ENST00000541549ATP2C2chr16

84432115

-EIF3Achr10

120817711

+
In-frameENST00000416219ENST00000369144ATP2C2chr16

84432115

-EIF3Achr10

120817711

+
In-frameENST00000416219ENST00000541549ATP2C2chr16

84432115

-EIF3Achr10

120817711

+
intron-3CDSENST00000420010ENST00000369144ATP2C2chr16

84432115

-EIF3Achr10

120817711

+
intron-3CDSENST00000420010ENST00000541549ATP2C2chr16

84432115

-EIF3Achr10

120817711

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000262429ATP2C2chr1684432115-ENST00000369144EIF3Achr10120817711+389928820332875280
ENST00000262429ATP2C2chr1684432115-ENST00000541549EIF3Achr10120817711+295028810841926280
ENST00000416219ATP2C2chr1684432115-ENST00000369144EIF3Achr10120817711+389928820332875280
ENST00000416219ATP2C2chr1684432115-ENST00000541549EIF3Achr10120817711+295028810841926280

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000262429ENST00000369144ATP2C2chr1684432115-EIF3Achr10120817711+0.0066167780.9933832
ENST00000262429ENST00000541549ATP2C2chr1684432115-EIF3Achr10120817711+0.0141541830.98584574
ENST00000416219ENST00000369144ATP2C2chr1684432115-EIF3Achr10120817711+0.0066167780.9933832
ENST00000416219ENST00000541549ATP2C2chr1684432115-EIF3Achr10120817711+0.0141541830.98584574

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Fusion Genomic Features for ATP2C2-EIF3A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ATP2C2-EIF3A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:84432115/chr10:120817711)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATP2C2

O75185

EIF3A

Q14152

FUNCTION: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. {ECO:0000250}.FUNCTION: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632, PubMed:11169732). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773, PubMed:27462815). {ECO:0000255|HAMAP-Rule:MF_03000, ECO:0000269|PubMed:11169732, ECO:0000269|PubMed:17581632, ECO:0000269|PubMed:25849773, ECO:0000269|PubMed:27462815}.; FUNCTION: (Microbial infection) Essential for the initiation of translation on type-1 viral ribosomal entry sites (IRESs), like for HCV, PV, EV71 or BEV translation (PubMed:23766293, PubMed:24357634). {ECO:0000269|PubMed:23766293, ECO:0000269|PubMed:24357634}.; FUNCTION: (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426). {ECO:0000269|PubMed:18056426}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEIF3Achr16:84432115chr10:120817711ENST0000036914402282_12001383.0Coiled coilOntology_term=ECO:0000255
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022576_87501383.0Compositional biasNote=Glu-rich
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022925_129401383.0Compositional biasNote=Asp-rich
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022315_49801383.0DomainPCI
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022925_117201383.0RegionNote=25 X 10 AA approximate tandem repeats of [DE]-[DE]-[DE]-R-[SEVGFPILV]-[HPSN]-[RSW]-[RL]-[DRGTIHN]-[EPMANLGDT]
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221003_101201383.0RepeatNote=9
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221013_102201383.0RepeatNote=10
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221023_103201383.0RepeatNote=11
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221033_104201383.0RepeatNote=12
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221043_105201383.0RepeatNote=13
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221054_106301383.0RepeatNote=14
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221064_107301383.0RepeatNote=15
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221074_108301383.0RepeatNote=16
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221084_109301383.0RepeatNote=17
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221094_110301383.0RepeatNote=18
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221104_111301383.0RepeatNote=19
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221114_112301383.0RepeatNote=20
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221124_113301383.0RepeatNote=21
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221134_114301383.0RepeatNote=22
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221144_115201383.0RepeatNote=23%3B truncated
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221153_116201383.0RepeatNote=24
TgeneEIF3Achr16:84432115chr10:120817711ENST000003691440221163_117201383.0RepeatNote=25%3B approximate
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022925_93401383.0RepeatNote=1
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022935_94201383.0RepeatNote=2%3B truncated
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022943_95201383.0RepeatNote=3
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022953_96201383.0RepeatNote=4
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022963_97201383.0RepeatNote=5
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022973_98201383.0RepeatNote=6
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022983_99201383.0RepeatNote=7
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022993_100201383.0RepeatNote=8

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127114_1190947.0Compositional biasNote=Poly-Leu
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127128_1290947.0Topological domainExtracellular
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127151_2310947.0Topological domainCytoplasmic
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-1271_1060947.0Topological domainCytoplasmic
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127253_2930947.0Topological domainExtracellular
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127315_3310947.0Topological domainCytoplasmic
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127353_7500947.0Topological domainExtracellular
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127772_8040947.0Topological domainCytoplasmic
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127826_8370947.0Topological domainExtracellular
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127856_8740947.0Topological domainCytoplasmic
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127896_9050947.0Topological domainExtracellular
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127927_9460947.0Topological domainCytoplasmic
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127107_1270947.0TransmembraneHelical%3B Name%3D1
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127130_1500947.0TransmembraneHelical%3B Name%3D2
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127232_2520947.0TransmembraneHelical%3B Name%3D3
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127294_3140947.0TransmembraneHelical%3B Name%3D4
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127332_3520947.0TransmembraneHelical%3B Name%3D5
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127751_7710947.0TransmembraneHelical%3B Name%3D6
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127805_8250947.0TransmembraneHelical%3B Name%3D7
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127838_8550947.0TransmembraneHelical%3B Name%3D8
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127875_8950947.0TransmembraneHelical%3B Name%3D9
HgeneATP2C2chr16:84432115chr10:120817711ENST00000262429-127906_9260947.0TransmembraneHelical%3B Name%3D10


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Fusion Gene Sequence for ATP2C2-EIF3A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>7902_7902_1_ATP2C2-EIF3A_ATP2C2_chr16_84432115_ENST00000262429_EIF3A_chr10_120817711_ENST00000369144_length(transcript)=3899nt_BP=288nt
GGGTCCGGCCCAGGAGGCTTGGGCGCGCGCAGCCATCCCGGGCCTCGCCGGGGACCTAGGGACGCAGGCAACGCCTGCGCCCGCTCACCA
TGGTCGAGGGACGCGTCTCCGAGTTCCTGAAGAAACTCGGCTTCTCGGGCGGGGGCCGCCAGTACCAGGCGCTGGAGAAGGACGAAGAGG
AAGCCTTGGAGTGAGCTGAAAGCCATCGAGAAAGAGAAGAAGGTGACAGCCCTGCCCCCCAAGGAAGCGTGCAAATGCCAGAAAGAGGAT
TTGGCCAGAGCGTTTTGTTAAGTTCTTGGAGACGTGCTGATGACAGGAAAGATGACCGGGTGGAAGAGCGGGACCCTCCTCGTCGAGTTC
CTCCCCCAGCTCTTTCAAGAGACCGAGAAAGAGACCGAGACCGAGAAAGAGAAGGTGAAAAAGAGAAGGCCTCATGGAGAGCTGAGAAAG
ATAGGGAATCTCTCCGTCGTACTAAAAATGAGACTGATGAAGATGGATGGACCACAGTACGACGTTAAGTCTCAAGATAATGGATTTAAA
CTGGTGTCTTAAATAGGTTTGATCACATTCAAGGATTATTATACTTGTGCTTCAACCAATCTAAATTGGATTCTTTAATGTTGTTTCACC
ATAACACAAAAAGCATGAACTTGTATTAATCCTATATAATAGATTGATCATGCACCATATCCACAGGAGGTTGGAAAAACCATGCCATTT
TCTGGAATTTAAGGGTGTTGCATTATTTCATCAATCATTTGTTGACAAAAAAGAAAAACTAAAAAATAAATTTAAAATGTGACCCTTCAG
GTATTGAGTAACACCTTTATCTTGGTATAGAACTGATACTTTTTTTTTGATTTTGAAATATCTGATAATAATTTGGAATGAAGTAAGGTT
CTGTTAAAATATATTTGAAGACCCTTTAAAGCAGTGAATCTGAAACAATTTTCACACCCTTAAGTGGTTGATACGTACCTATTTTAGGTA
TTTTGAGGTATTTACCATAAACTAAATTTAGAAATTTTTTAGATTCACTTGAAGTAAACATTACAAACATTGGATACGGTGGGGTTTTCT
TTAGATTTTACTTGAGAGAAGGTGAGTACAAAGCAATTTGCAGTTGTTGTAATGACAAGATTACTGCGCAAGTGTGAATCCAAACAGTAT
AGCTTTTAAATTTTAAAGCATTTGGTAAATTATCGCTGAGTTTTTTTCTGTTGCCAATAGCAAACTGCTTTTCCATTAATGGAGAATTCA
TGCCTTTCAAGCATTTTAAATATGACAATATTTATAAATGTATGGTTTGGAGGAATCGTTTAAATTCTCTTTCCTAATTTTCTTTCTTTT
GAAGATAGATTCTTTCAACAAGTAATTTGTAGTAATGACTGTGTTGACTTCAATTTTGGAGCGCAGTAGCTATGTTAAAGATGAACTATT
TGGTCTCATTGAAGCCAACACAGAACTTGCTGCTGTGTTTTTTCTTCAGTGATAAATAAAATACTTACAGAATTTGTTTTAGTGTTGATT
TGTGGTTATAGTATTTTGTTTATAATGGTAAGTTTGCATATTCAGTTGAGTTTTTTTTACTTGAATTTTTATCAGTGCCATTAAATGTCT
GTGTTTAGTATCAATGAAAATGAACCTAAATATAACAAAGAAAGCATATGTGGCTAGGATGTCCCCCTAACATGTCTTCCTTTGTTAATG
CAGGGATGAAGGTGGCTGGAGAAGAGGACCAGCTGAGGAATCTTCAAGCTGGAGAGACTCAAGTCGCCGGGACGATAGGGATAGGGATGA
CCGTCGCCGTGAGAGGGATGACCGGCGTGATCTAAGAGAAAGACGAGATCTAAGAGACGACAGGGACCGAAGAGGACCTCCACTCAGATC
AGAACGTGAAGAAGGTGGATGGAGAGAGAAAGAAAAAGCCAGAGAGGAGAGCTGGGGTCCACCTCGAGAATCAAGGCCATCAGAAGAACG
TGAATGGGACAGAGAAAAAGAAAGGGACAGAGATAATCAAGATCGGGAGGAGAATGACAAGGACCCTGAGAGAGAAAGGGACAGAGAGAG
AGATGTGGATCGAGAGGATCGCTTCAGAAGACCTAGGGAGTGGAGACGTGGAGAAGGGCGAGATGAGGACAGGTCTCATAGAAGAGATGA
AGAGCGGCCCCGGCGTCTGGGGGATGATGAAGATAGAGAGCCCTCTCTTAGACCAGACGATGATCGGGTTCCCCGGCGTGGCATGGATGA
TGACAGAGGCCCTAGACGTGGTCCTGAGGAAGATAGGTTCTCTCGTCGTGGGGCAGACGATGACCGGCCTTCCTGGCGTAACACAGATGA
TGACAGGCCTCCCAGACGAATTGCCGATGAAGACAGGGGAAACTGGCGTCATGCGGATGATGACAGACCACCTAGACGAGGACTGGATGA
GGACAGAGGAAGCTGGCGAACAGCTGATGAGGACAGAGGACCAAGACGTGGGATGGATGATGACCGGGGGCCGAGGCGAGGAGGCGCTGA
TGATGAGCGATCATCCTGGCGTAATGCTGATGATGACCGGGGTCCCAGGCGAGGGTTGGATGATGATCGGGGTCCCAGGCGAGGCATGGA
TGATGACCGGGGTCCCAGGCGAGGCATGGATGATGACCGGGGTCCCAGGCGAGGCATGGATGATGACCGGGGTCCCAGGCGAGGGTTGGA
TGATGATCGAGGACCTTGGAGGAACGCCGATGATGACAGAATTCCCAGGCGTGGTGCAGAGGATGACAGGGGCCCTTGGAGAAACATGGA
TGATGATCGCCTTTCAAGACGTGCTGATGATGATCGGTTTCCCAGACGGGGTGATGACTCAAGACCTGGTCCTTGGAGACCATTAGTCAA
GCCAGGACTCTCGTTGGGGAGATAGAGATTCAGAAGGCACCTGGAGAAAAGGACCTGAAGCAGATTCTGAGTGGAGAAGAGGCCCGCCAG
AGAAAGCGGGAAGAGAGAGAGCGCGCCGAACGAGCAAAACGCGAGGAAGAGCTACGAGAGTATCAGGAGCGGGTGAAGAAATTAGAAGAA
GTGGAAAGGAAAAAACGCCAAAGGGAGTTGGAAATTGAAGAACGAGAACGGCGTAGAGAGGAAGAGAGAAGACTTGGCGATAGTTCCCTT
TCTAGAAAGGAAAAACTTAAACAGTTTGAAGAGCGATTAGCAGAAGAAAGGCATAATCGATTGGAAGAACGGAAAAGGCAGCGTAAAGAA
GAACGCAGGATAACATACTATAGAGAAAAAGAAGAGGAGGAGCAGAGAAGGGCAGAAGAACAAATGCTAAAAGATTACTACAATGCAGCT
AGAACGTGAAAAGGCTCTTGAACATAAGAATCGAATGTCACGAATGCTTGAAGACAGAGATTTATTCGTAATGCGACTCAAAGCTGCACG
GCAGTCTGTTTATGAGATTGACTATTTTGAAAGAGCCAAACGTTTGGAAGAAATTCCTTTGATAAAGAGCGCTTACGAGGAACAGAGAAT
TAAAGACATGGATCTGTGGGAGCAACAAGAGGAAGAAAGAGACCTTGAGGAATTGGATCCAGATTTTATCATGGCTAAACAGGTTGAACA
ACTGGAGAAAGAAAAGAAAGAACTTCAAGAACGCCTAAAGAATCAAGAAAAGAAGAAAAGAGCGCCTTGAGAGTCTGAATATTCAGCGTG
AGAAAGAAGAATTGGAACAGAGGGAAGCTGAACTCCAGAAAGTGCGGAAGGCTGAGGAAGAGAGGCTGCGCCAGGAAGCAAAGGAGAGAG
AGAAGGAGCGTATCTTACAGGAACATGAACAAATCAAAAAGAAAACTGTCCGAGAGCGTTTGGAGCAGATCAAGAAAACAGAACTGGGTG

>7902_7902_1_ATP2C2-EIF3A_ATP2C2_chr16_84432115_ENST00000262429_EIF3A_chr10_120817711_ENST00000369144_length(amino acids)=280AA_BP=
MTRTLREKGTEREMWIERIASEDLGSGDVEKGEMRTGLIEEMKSGPGVWGMMKIESPLLDQTMIGFPGVAWMMTEALDVVLRKIGSLVVG
QTMTGLPGVTQMMTGLPDELPMKTGETGVMRMMTDHLDEDWMRTEEAGEQLMRTEDQDVGWMMTGGRGEEALMMSDHPGVMLMMTGVPGE
GWMMIGVPGEAWMMTGVPGEAWMMTGVPGEAWMMTGVPGEGWMMIEDLGGTPMMTEFPGVVQRMTGALGETWMMIAFQDVLMMIGFPDGV

--------------------------------------------------------------
>7902_7902_2_ATP2C2-EIF3A_ATP2C2_chr16_84432115_ENST00000262429_EIF3A_chr10_120817711_ENST00000541549_length(transcript)=2950nt_BP=288nt
GGGTCCGGCCCAGGAGGCTTGGGCGCGCGCAGCCATCCCGGGCCTCGCCGGGGACCTAGGGACGCAGGCAACGCCTGCGCCCGCTCACCA
TGGTCGAGGGACGCGTCTCCGAGTTCCTGAAGAAACTCGGCTTCTCGGGCGGGGGCCGCCAGTACCAGGCGCTGGAGAAGGACGAAGAGG
AAGCCTTGGAGTGAGCTGAAAGCCATCGAGAAAGAGAAGAAGGTGACAGCCCTGCCCCCCAAGGAAGCGTGCAAATGCCAGAAAGAGGAT
TTGGCCAGAGCGTTTTGTTAAGTTCTTGGAGACGTGCTGATGACAGGAAAGATGACCGGGTGGAAGAGCGGGACCCTCCTCGTCGAGTTC
CTCCCCCAGCTCTTTCAAGAGACCGAGAAAGAGACCGAGACCGAGAAAGAGAAGGTGAAAAAGAGAAGGCCTCATGGAGAGCTGAGAAAG
ATAGGGAATCTCTCCGTCGTACTAAAAATGAGACTGATGAAGATGGATGGACCACAGTACGACGTTAAGTCTCAAGATAATGGATTTAAA
CTGGTGTCTTAAATAGGTTTGATCACATTCAAGGATTATTATACTTGTGCTTCAACCAATCTAAATTGGATTCTTTAATGTTGTTTCACC
ATAACACAAAAAGCATGAACTTGTATTAATCCTATATAATAGATTGATCATGCACCATATCCACAGGAGGTTGGAAAAACCATGCCATTT
TCTGGAATTTAAGGGTGTTGCATTATTTCATCAATCATTTGTTGGGATGAAGGTGGCTGGAGAAGAGGACCAGCTGAGGAATCTTCAAGC
TGGAGAGACTCAAGTCGCCGGGACGATAGGGATAGGGATGACCGTCGCCGTGAGAGGGATGACCGGCGTGATCTAAGAGAAAGACGAGAT
CTAAGAGACGACAGGGACCGAAGAGGACCTCCACTCAGATCAGAACGTGAAGAAGGTGGATGGAGAGAGAAAGAAAAAGCCAGAGAGGAG
AGCTGGGGTCCACCTCGAGAATCAAGGCCATCAGAAGAACGTGAATGGGACAGAGAAAAAGAAAGGGACAGAGATAATCAAGATCGGGAG
GAGAATGACAAGGACCCTGAGAGAGAAAGGGACAGAGAGAGAGATGTGGATCGAGAGGATCGCTTCAGAAGACCTAGGGAGTGGAGACGT
GGAGAAGGGCGAGATGAGGACAGGTCTCATAGAAGAGATGAAGAGCGGCCCCGGCGTCTGGGGGATGATGAAGATAGAGAGCCCTCTCTT
AGACCAGACGATGATCGGGTTCCCCGGCGTGGCATGGATGATGACAGAGGCCCTAGACGTGGTCCTGAGGAAGATAGGTTCTCTCGTCGT
GGGGCAGACGATGACCGGCCTTCCTGGCGTAACACAGATGATGACAGGCCTCCCAGACGAATTGCCGATGAAGACAGGGGAAACTGGCGT
CATGCGGATGATGACAGACCACCTAGACGAGGACTGGATGAGGACAGAGGAAGCTGGCGAACAGCTGATGAGGACAGAGGACCAAGACGT
GGGATGGATGATGACCGGGGGCCGAGGCGAGGAGGCGCTGATGATGAGCGATCATCCTGGCGTAATGCTGATGATGACCGGGGTCCCAGG
CGAGGGTTGGATGATGATCGGGGTCCCAGGCGAGGCATGGATGATGACCGGGGTCCCAGGCGAGGCATGGATGATGACCGGGGTCCCAGG
CGAGGCATGGATGATGACCGGGGTCCCAGGCGAGGGTTGGATGATGATCGAGGACCTTGGAGGAACGCCGATGATGACAGAATTCCCAGG
CGTGGTGCAGAGGATGACAGGGGCCCTTGGAGAAACATGGATGATGATCGCCTTTCAAGACGTGCTGATGATGATCGGTTTCCCAGACGG
GGTGATGACTCAAGACCTGGTCCTTGGAGACCATTAGTCAAGCCAGGACTCTCGTTGGGGAGATAGAGATTCAGAAGGCACCTGGAGAAA
AGGACCTGAAGCAGATTCTGAGTGGAGAAGAGGCCCGCCAGAGAAAGCGGGAAGAGAGAGAGCGCGCCGAACGAGCAAAACGCGAGGAAG
AGCTACGAGAGTATCAGGAGCGGGTGAAGAAATTAGAAGAAGTGGAAAGGAAAAAACGCCAAAGGGAGTTGGAAATTGAAGAACGAGAAC
GGCGTAGAGAGGAAGAGAGAAGACTTGGCGATAGTTCCCTTTCTAGAAAGGAAAAACTTAAACAGTTTGAAGAGCGATTAGCAGAAGAAA
GGCATAATCGATTGGAAGAACGGAAAAGGCAGCGTAAAGAAGAACGCAGGATAACATACTATAGAGAAAAAGAAGAGGAGGAGCAGAGAA
GGGCAGAAGAACAAATGCTAAAAGATTACTACAATGCAGCTAGAACGTGAAAAGGCTCTTGAACATAAGAATCGAATGTCACGAATGCTT
GAAGACAGAGATTTATTCGTAATGCGACTCAAAGCTGCACGGCAGTCTGTTTATGAGATTGACTATTTTGAAAGAGCCAAACGTTTGGAA
GAAATTCCTTTGATAAAGAGCGCTTACGAGGAACAGAGAATTAAAGACATGGATCTGTGGGAGCAACAAGAGGAAGAAAGAGACCTTGAG
GAATTGGATCCAGATTTTATCATGGCTAAACAGGTTGAACAACTGGAGAAAGAAAAGAAAGAACTTCAAGAACGCCTAAAGAATCAAGAA
AAGAAGAAAAGAGCGCCTTGAGAGTCTGAATATTCAGCGTGAGAAAGAAGAATTGGAACAGAGGGAAGCTGAACTCCAGAAAGTGCGGAA
GGCTGAGGAAGAGAGGCTGCGCCAGGAAGCAAAGGAGAGAGAGAAGGAGCGTATCTTACAGGAACATGAACAAATCAAAAAGAAAACTGT

>7902_7902_2_ATP2C2-EIF3A_ATP2C2_chr16_84432115_ENST00000262429_EIF3A_chr10_120817711_ENST00000541549_length(amino acids)=280AA_BP=
MTRTLREKGTEREMWIERIASEDLGSGDVEKGEMRTGLIEEMKSGPGVWGMMKIESPLLDQTMIGFPGVAWMMTEALDVVLRKIGSLVVG
QTMTGLPGVTQMMTGLPDELPMKTGETGVMRMMTDHLDEDWMRTEEAGEQLMRTEDQDVGWMMTGGRGEEALMMSDHPGVMLMMTGVPGE
GWMMIGVPGEAWMMTGVPGEAWMMTGVPGEAWMMTGVPGEGWMMIEDLGGTPMMTEFPGVVQRMTGALGETWMMIAFQDVLMMIGFPDGV

--------------------------------------------------------------
>7902_7902_3_ATP2C2-EIF3A_ATP2C2_chr16_84432115_ENST00000416219_EIF3A_chr10_120817711_ENST00000369144_length(transcript)=3899nt_BP=288nt
GGGTCCGGCCCAGGAGGCTTGGGCGCGCGCAGCCATCCCGGGCCTCGCCGGGGACCTAGGGACGCAGGCAACGCCTGCGCCCGCTCACCA
TGGTCGAGGGACGCGTCTCCGAGTTCCTGAAGAAACTCGGCTTCTCGGGCGGGGGCCGCCAGTACCAGGCGCTGGAGAAGGACGAAGAGG
AAGCCTTGGAGTGAGCTGAAAGCCATCGAGAAAGAGAAGAAGGTGACAGCCCTGCCCCCCAAGGAAGCGTGCAAATGCCAGAAAGAGGAT
TTGGCCAGAGCGTTTTGTTAAGTTCTTGGAGACGTGCTGATGACAGGAAAGATGACCGGGTGGAAGAGCGGGACCCTCCTCGTCGAGTTC
CTCCCCCAGCTCTTTCAAGAGACCGAGAAAGAGACCGAGACCGAGAAAGAGAAGGTGAAAAAGAGAAGGCCTCATGGAGAGCTGAGAAAG
ATAGGGAATCTCTCCGTCGTACTAAAAATGAGACTGATGAAGATGGATGGACCACAGTACGACGTTAAGTCTCAAGATAATGGATTTAAA
CTGGTGTCTTAAATAGGTTTGATCACATTCAAGGATTATTATACTTGTGCTTCAACCAATCTAAATTGGATTCTTTAATGTTGTTTCACC
ATAACACAAAAAGCATGAACTTGTATTAATCCTATATAATAGATTGATCATGCACCATATCCACAGGAGGTTGGAAAAACCATGCCATTT
TCTGGAATTTAAGGGTGTTGCATTATTTCATCAATCATTTGTTGACAAAAAAGAAAAACTAAAAAATAAATTTAAAATGTGACCCTTCAG
GTATTGAGTAACACCTTTATCTTGGTATAGAACTGATACTTTTTTTTTGATTTTGAAATATCTGATAATAATTTGGAATGAAGTAAGGTT
CTGTTAAAATATATTTGAAGACCCTTTAAAGCAGTGAATCTGAAACAATTTTCACACCCTTAAGTGGTTGATACGTACCTATTTTAGGTA
TTTTGAGGTATTTACCATAAACTAAATTTAGAAATTTTTTAGATTCACTTGAAGTAAACATTACAAACATTGGATACGGTGGGGTTTTCT
TTAGATTTTACTTGAGAGAAGGTGAGTACAAAGCAATTTGCAGTTGTTGTAATGACAAGATTACTGCGCAAGTGTGAATCCAAACAGTAT
AGCTTTTAAATTTTAAAGCATTTGGTAAATTATCGCTGAGTTTTTTTCTGTTGCCAATAGCAAACTGCTTTTCCATTAATGGAGAATTCA
TGCCTTTCAAGCATTTTAAATATGACAATATTTATAAATGTATGGTTTGGAGGAATCGTTTAAATTCTCTTTCCTAATTTTCTTTCTTTT
GAAGATAGATTCTTTCAACAAGTAATTTGTAGTAATGACTGTGTTGACTTCAATTTTGGAGCGCAGTAGCTATGTTAAAGATGAACTATT
TGGTCTCATTGAAGCCAACACAGAACTTGCTGCTGTGTTTTTTCTTCAGTGATAAATAAAATACTTACAGAATTTGTTTTAGTGTTGATT
TGTGGTTATAGTATTTTGTTTATAATGGTAAGTTTGCATATTCAGTTGAGTTTTTTTTACTTGAATTTTTATCAGTGCCATTAAATGTCT
GTGTTTAGTATCAATGAAAATGAACCTAAATATAACAAAGAAAGCATATGTGGCTAGGATGTCCCCCTAACATGTCTTCCTTTGTTAATG
CAGGGATGAAGGTGGCTGGAGAAGAGGACCAGCTGAGGAATCTTCAAGCTGGAGAGACTCAAGTCGCCGGGACGATAGGGATAGGGATGA
CCGTCGCCGTGAGAGGGATGACCGGCGTGATCTAAGAGAAAGACGAGATCTAAGAGACGACAGGGACCGAAGAGGACCTCCACTCAGATC
AGAACGTGAAGAAGGTGGATGGAGAGAGAAAGAAAAAGCCAGAGAGGAGAGCTGGGGTCCACCTCGAGAATCAAGGCCATCAGAAGAACG
TGAATGGGACAGAGAAAAAGAAAGGGACAGAGATAATCAAGATCGGGAGGAGAATGACAAGGACCCTGAGAGAGAAAGGGACAGAGAGAG
AGATGTGGATCGAGAGGATCGCTTCAGAAGACCTAGGGAGTGGAGACGTGGAGAAGGGCGAGATGAGGACAGGTCTCATAGAAGAGATGA
AGAGCGGCCCCGGCGTCTGGGGGATGATGAAGATAGAGAGCCCTCTCTTAGACCAGACGATGATCGGGTTCCCCGGCGTGGCATGGATGA
TGACAGAGGCCCTAGACGTGGTCCTGAGGAAGATAGGTTCTCTCGTCGTGGGGCAGACGATGACCGGCCTTCCTGGCGTAACACAGATGA
TGACAGGCCTCCCAGACGAATTGCCGATGAAGACAGGGGAAACTGGCGTCATGCGGATGATGACAGACCACCTAGACGAGGACTGGATGA
GGACAGAGGAAGCTGGCGAACAGCTGATGAGGACAGAGGACCAAGACGTGGGATGGATGATGACCGGGGGCCGAGGCGAGGAGGCGCTGA
TGATGAGCGATCATCCTGGCGTAATGCTGATGATGACCGGGGTCCCAGGCGAGGGTTGGATGATGATCGGGGTCCCAGGCGAGGCATGGA
TGATGACCGGGGTCCCAGGCGAGGCATGGATGATGACCGGGGTCCCAGGCGAGGCATGGATGATGACCGGGGTCCCAGGCGAGGGTTGGA
TGATGATCGAGGACCTTGGAGGAACGCCGATGATGACAGAATTCCCAGGCGTGGTGCAGAGGATGACAGGGGCCCTTGGAGAAACATGGA
TGATGATCGCCTTTCAAGACGTGCTGATGATGATCGGTTTCCCAGACGGGGTGATGACTCAAGACCTGGTCCTTGGAGACCATTAGTCAA
GCCAGGACTCTCGTTGGGGAGATAGAGATTCAGAAGGCACCTGGAGAAAAGGACCTGAAGCAGATTCTGAGTGGAGAAGAGGCCCGCCAG
AGAAAGCGGGAAGAGAGAGAGCGCGCCGAACGAGCAAAACGCGAGGAAGAGCTACGAGAGTATCAGGAGCGGGTGAAGAAATTAGAAGAA
GTGGAAAGGAAAAAACGCCAAAGGGAGTTGGAAATTGAAGAACGAGAACGGCGTAGAGAGGAAGAGAGAAGACTTGGCGATAGTTCCCTT
TCTAGAAAGGAAAAACTTAAACAGTTTGAAGAGCGATTAGCAGAAGAAAGGCATAATCGATTGGAAGAACGGAAAAGGCAGCGTAAAGAA
GAACGCAGGATAACATACTATAGAGAAAAAGAAGAGGAGGAGCAGAGAAGGGCAGAAGAACAAATGCTAAAAGATTACTACAATGCAGCT
AGAACGTGAAAAGGCTCTTGAACATAAGAATCGAATGTCACGAATGCTTGAAGACAGAGATTTATTCGTAATGCGACTCAAAGCTGCACG
GCAGTCTGTTTATGAGATTGACTATTTTGAAAGAGCCAAACGTTTGGAAGAAATTCCTTTGATAAAGAGCGCTTACGAGGAACAGAGAAT
TAAAGACATGGATCTGTGGGAGCAACAAGAGGAAGAAAGAGACCTTGAGGAATTGGATCCAGATTTTATCATGGCTAAACAGGTTGAACA
ACTGGAGAAAGAAAAGAAAGAACTTCAAGAACGCCTAAAGAATCAAGAAAAGAAGAAAAGAGCGCCTTGAGAGTCTGAATATTCAGCGTG
AGAAAGAAGAATTGGAACAGAGGGAAGCTGAACTCCAGAAAGTGCGGAAGGCTGAGGAAGAGAGGCTGCGCCAGGAAGCAAAGGAGAGAG
AGAAGGAGCGTATCTTACAGGAACATGAACAAATCAAAAAGAAAACTGTCCGAGAGCGTTTGGAGCAGATCAAGAAAACAGAACTGGGTG

>7902_7902_3_ATP2C2-EIF3A_ATP2C2_chr16_84432115_ENST00000416219_EIF3A_chr10_120817711_ENST00000369144_length(amino acids)=280AA_BP=
MTRTLREKGTEREMWIERIASEDLGSGDVEKGEMRTGLIEEMKSGPGVWGMMKIESPLLDQTMIGFPGVAWMMTEALDVVLRKIGSLVVG
QTMTGLPGVTQMMTGLPDELPMKTGETGVMRMMTDHLDEDWMRTEEAGEQLMRTEDQDVGWMMTGGRGEEALMMSDHPGVMLMMTGVPGE
GWMMIGVPGEAWMMTGVPGEAWMMTGVPGEAWMMTGVPGEGWMMIEDLGGTPMMTEFPGVVQRMTGALGETWMMIAFQDVLMMIGFPDGV

--------------------------------------------------------------
>7902_7902_4_ATP2C2-EIF3A_ATP2C2_chr16_84432115_ENST00000416219_EIF3A_chr10_120817711_ENST00000541549_length(transcript)=2950nt_BP=288nt
GGGTCCGGCCCAGGAGGCTTGGGCGCGCGCAGCCATCCCGGGCCTCGCCGGGGACCTAGGGACGCAGGCAACGCCTGCGCCCGCTCACCA
TGGTCGAGGGACGCGTCTCCGAGTTCCTGAAGAAACTCGGCTTCTCGGGCGGGGGCCGCCAGTACCAGGCGCTGGAGAAGGACGAAGAGG
AAGCCTTGGAGTGAGCTGAAAGCCATCGAGAAAGAGAAGAAGGTGACAGCCCTGCCCCCCAAGGAAGCGTGCAAATGCCAGAAAGAGGAT
TTGGCCAGAGCGTTTTGTTAAGTTCTTGGAGACGTGCTGATGACAGGAAAGATGACCGGGTGGAAGAGCGGGACCCTCCTCGTCGAGTTC
CTCCCCCAGCTCTTTCAAGAGACCGAGAAAGAGACCGAGACCGAGAAAGAGAAGGTGAAAAAGAGAAGGCCTCATGGAGAGCTGAGAAAG
ATAGGGAATCTCTCCGTCGTACTAAAAATGAGACTGATGAAGATGGATGGACCACAGTACGACGTTAAGTCTCAAGATAATGGATTTAAA
CTGGTGTCTTAAATAGGTTTGATCACATTCAAGGATTATTATACTTGTGCTTCAACCAATCTAAATTGGATTCTTTAATGTTGTTTCACC
ATAACACAAAAAGCATGAACTTGTATTAATCCTATATAATAGATTGATCATGCACCATATCCACAGGAGGTTGGAAAAACCATGCCATTT
TCTGGAATTTAAGGGTGTTGCATTATTTCATCAATCATTTGTTGGGATGAAGGTGGCTGGAGAAGAGGACCAGCTGAGGAATCTTCAAGC
TGGAGAGACTCAAGTCGCCGGGACGATAGGGATAGGGATGACCGTCGCCGTGAGAGGGATGACCGGCGTGATCTAAGAGAAAGACGAGAT
CTAAGAGACGACAGGGACCGAAGAGGACCTCCACTCAGATCAGAACGTGAAGAAGGTGGATGGAGAGAGAAAGAAAAAGCCAGAGAGGAG
AGCTGGGGTCCACCTCGAGAATCAAGGCCATCAGAAGAACGTGAATGGGACAGAGAAAAAGAAAGGGACAGAGATAATCAAGATCGGGAG
GAGAATGACAAGGACCCTGAGAGAGAAAGGGACAGAGAGAGAGATGTGGATCGAGAGGATCGCTTCAGAAGACCTAGGGAGTGGAGACGT
GGAGAAGGGCGAGATGAGGACAGGTCTCATAGAAGAGATGAAGAGCGGCCCCGGCGTCTGGGGGATGATGAAGATAGAGAGCCCTCTCTT
AGACCAGACGATGATCGGGTTCCCCGGCGTGGCATGGATGATGACAGAGGCCCTAGACGTGGTCCTGAGGAAGATAGGTTCTCTCGTCGT
GGGGCAGACGATGACCGGCCTTCCTGGCGTAACACAGATGATGACAGGCCTCCCAGACGAATTGCCGATGAAGACAGGGGAAACTGGCGT
CATGCGGATGATGACAGACCACCTAGACGAGGACTGGATGAGGACAGAGGAAGCTGGCGAACAGCTGATGAGGACAGAGGACCAAGACGT
GGGATGGATGATGACCGGGGGCCGAGGCGAGGAGGCGCTGATGATGAGCGATCATCCTGGCGTAATGCTGATGATGACCGGGGTCCCAGG
CGAGGGTTGGATGATGATCGGGGTCCCAGGCGAGGCATGGATGATGACCGGGGTCCCAGGCGAGGCATGGATGATGACCGGGGTCCCAGG
CGAGGCATGGATGATGACCGGGGTCCCAGGCGAGGGTTGGATGATGATCGAGGACCTTGGAGGAACGCCGATGATGACAGAATTCCCAGG
CGTGGTGCAGAGGATGACAGGGGCCCTTGGAGAAACATGGATGATGATCGCCTTTCAAGACGTGCTGATGATGATCGGTTTCCCAGACGG
GGTGATGACTCAAGACCTGGTCCTTGGAGACCATTAGTCAAGCCAGGACTCTCGTTGGGGAGATAGAGATTCAGAAGGCACCTGGAGAAA
AGGACCTGAAGCAGATTCTGAGTGGAGAAGAGGCCCGCCAGAGAAAGCGGGAAGAGAGAGAGCGCGCCGAACGAGCAAAACGCGAGGAAG
AGCTACGAGAGTATCAGGAGCGGGTGAAGAAATTAGAAGAAGTGGAAAGGAAAAAACGCCAAAGGGAGTTGGAAATTGAAGAACGAGAAC
GGCGTAGAGAGGAAGAGAGAAGACTTGGCGATAGTTCCCTTTCTAGAAAGGAAAAACTTAAACAGTTTGAAGAGCGATTAGCAGAAGAAA
GGCATAATCGATTGGAAGAACGGAAAAGGCAGCGTAAAGAAGAACGCAGGATAACATACTATAGAGAAAAAGAAGAGGAGGAGCAGAGAA
GGGCAGAAGAACAAATGCTAAAAGATTACTACAATGCAGCTAGAACGTGAAAAGGCTCTTGAACATAAGAATCGAATGTCACGAATGCTT
GAAGACAGAGATTTATTCGTAATGCGACTCAAAGCTGCACGGCAGTCTGTTTATGAGATTGACTATTTTGAAAGAGCCAAACGTTTGGAA
GAAATTCCTTTGATAAAGAGCGCTTACGAGGAACAGAGAATTAAAGACATGGATCTGTGGGAGCAACAAGAGGAAGAAAGAGACCTTGAG
GAATTGGATCCAGATTTTATCATGGCTAAACAGGTTGAACAACTGGAGAAAGAAAAGAAAGAACTTCAAGAACGCCTAAAGAATCAAGAA
AAGAAGAAAAGAGCGCCTTGAGAGTCTGAATATTCAGCGTGAGAAAGAAGAATTGGAACAGAGGGAAGCTGAACTCCAGAAAGTGCGGAA
GGCTGAGGAAGAGAGGCTGCGCCAGGAAGCAAAGGAGAGAGAGAAGGAGCGTATCTTACAGGAACATGAACAAATCAAAAAGAAAACTGT

>7902_7902_4_ATP2C2-EIF3A_ATP2C2_chr16_84432115_ENST00000416219_EIF3A_chr10_120817711_ENST00000541549_length(amino acids)=280AA_BP=
MTRTLREKGTEREMWIERIASEDLGSGDVEKGEMRTGLIEEMKSGPGVWGMMKIESPLLDQTMIGFPGVAWMMTEALDVVLRKIGSLVVG
QTMTGLPGVTQMMTGLPDELPMKTGETGVMRMMTDHLDEDWMRTEEAGEQLMRTEDQDVGWMMTGGRGEEALMMSDHPGVMLMMTGVPGE
GWMMIGVPGEAWMMTGVPGEAWMMTGVPGEAWMMTGVPGEGWMMIEDLGGTPMMTEFPGVVQRMTGALGETWMMIAFQDVLMMIGFPDGV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ATP2C2-EIF3A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneEIF3Achr16:84432115chr10:120817711ENST00000369144022664_83501383.0EIF3B


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATP2C2-EIF3A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATP2C2-EIF3A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource